Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calmodulin binding	TRPV1 IQGAP2 MYO9B MKNK2 OBSCN GRIN1 IQGAP1 TRPV4 IQGAP3 INVS	1.75e-06	230	124	10	GO:0005516
GeneOntologyMolecularFunction	actin filament binding	IQGAP2 MYO9B ACTN4 IQGAP1 TLN2 TRPV4 PPP1R9B IQGAP3	8.76e-05	227	124	8	GO:0051015
GeneOntologyMolecularFunction	small GTPase binding	RGPD2 ANKFY1 IQGAP2 MYO9B RGPD1 MYRIP IQGAP1 FGD6 IQGAP3	1.80e-04	321	124	9	GO:0031267
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	IQGAP2 OBSCN JPH2 IQGAP1	2.42e-04	49	124	4	GO:0005547
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE2A PDE4A PDE8B	3.30e-04	22	124	3	GO:0004115
GeneOntologyMolecularFunction	GTPase binding	RGPD2 ANKFY1 IQGAP2 MYO9B RGPD1 MYRIP IQGAP1 FGD6 IQGAP3	4.19e-04	360	124	9	GO:0051020
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE2A PDE4A PDE8B	4.30e-04	24	124	3	GO:0047555
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE2A PDE4A PDE8B	4.86e-04	25	124	3	GO:0004114
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE2A PDE4A PDE8B	6.13e-04	27	124	3	GO:0004112
GeneOntologyMolecularFunction	centromeric DNA binding	MSH2 KIF2C	7.87e-04	7	124	2	GO:0019237
GeneOntologyMolecularFunction	actin binding	IQGAP2 MYO9B MYRIP ACTN4 MEFV IQGAP1 TLN2 TRPV4 PPP1R9B IQGAP3	8.19e-04	479	124	10	GO:0003779
GeneOntologyMolecularFunction	interleukin-17 receptor activity	IL17RC IL17RA	1.05e-03	8	124	2	GO:0030368
GeneOntologyMolecularFunction	calcium channel activity	TRPV1 TRPC7 GRIN1 TRPV4 TRPV3	1.27e-03	129	124	5	GO:0005262
GeneOntologyMolecularFunction	cytoskeletal protein binding	IQGAP2 MYO9B OBSCN MYRIP EML2 ACTN4 SPAG6 CLIP1 MEFV IQGAP1 NFKB1 TLN2 TRPV4 PPP1R9B IQGAP3 KIF2C	1.28e-03	1099	124	16	GO:0008092
GeneOntologyMolecularFunction	phosphatidylinositol-4-phosphate binding	OBSCN JPH2 CERT1	1.44e-03	36	124	3	GO:0070273
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	ANKFY1 IQGAP2 OBSCN JPH2 CERT1 IQGAP1	1.53e-03	199	124	6	GO:1901981
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in mitotic cytokinesis	IQGAP2 IQGAP1 IQGAP3	2.07e-07	3	123	3	GO:1902407
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly	IQGAP2 IQGAP1 IQGAP3	2.07e-07	3	123	3	GO:1903475
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1 IQGAP3	2.07e-07	3	123	3	GO:1903479
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1 IQGAP3	8.24e-07	4	123	3	GO:2000689
GeneOntologyBiologicalProcess	actin filament-based process	RAP1GDS1 CARMIL2 IQGAP2 MYO9B PCLO OBSCN MYRIP ACTN4 SIX4 BCAR1 SPAG6 IQGAP1 TLN2 TRPV4 PPP1R9B FGD6 NLRP4 IQGAP3	7.76e-06	912	123	18	GO:0030029
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly	IQGAP2 IQGAP1 IQGAP3	1.69e-05	9	123	3	GO:0000915
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in cytokinesis	IQGAP2 IQGAP1 IQGAP3	1.69e-05	9	123	3	GO:0000912
GeneOntologyBiologicalProcess	actin cytoskeleton organization	RAP1GDS1 CARMIL2 IQGAP2 PCLO OBSCN ACTN4 SIX4 BCAR1 SPAG6 IQGAP1 TLN2 TRPV4 PPP1R9B FGD6 NLRP4 IQGAP3	2.32e-05	803	123	16	GO:0030036
GeneOntologyBiologicalProcess	actomyosin contractile ring organization	IQGAP2 IQGAP1 IQGAP3	2.41e-05	10	123	3	GO:0044837
GeneOntologyBiologicalProcess	cyclic nucleotide catabolic process	PDE2A PDE4A PDE8B	7.18e-05	14	123	3	GO:0009214
GeneOntologyCellularComponent	ruffle	PDE4A CARMIL2 MYO9B BCAR1 CLIP1 MEFV IQGAP1 TLN2 TRPV4 PPP1R9B FGD6	3.52e-08	206	122	11	GO:0001726
GeneOntologyCellularComponent	cell cortex	IQGAP2 MYO9B PCLO MYRIP EXOC3 ACTN4 CLIP1 IQGAP1 NEDD4 INSC TRPV4 PPP1R9B NLRP4 IQGAP3	3.64e-08	371	122	14	GO:0005938
GeneOntologyCellularComponent	cell leading edge	TRPV1 PDE4A CARMIL2 IQGAP2 MYO9B GRIN1 BCAR1 CLIP1 MEFV IQGAP1 TLN2 TRPV4 PPP1R9B FGD6 CLRN2	2.29e-07	500	122	15	GO:0031252
GeneOntologyCellularComponent	pinosome	ANKFY1 CARMIL2 CLIP1	3.09e-05	11	122	3	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANKFY1 CARMIL2 CLIP1	3.09e-05	11	122	3	GO:0044354
GeneOntologyCellularComponent	cell-cell junction	CARMIL2 CNTNAP1 OBSCN ACTN4 IQGAP1 NECTIN2 TLN2 TRPV4 PPP1R9B PATJ PCDH9 IQGAP3 NOTCH1	4.24e-05	591	122	13	GO:0005911
GeneOntologyCellularComponent	lamellipodium	CARMIL2 IQGAP2 MYO9B BCAR1 MEFV TRPV4 PPP1R9B FGD6	6.24e-05	230	122	8	GO:0030027
GeneOntologyCellularComponent	t-UTP complex	NOL11 UTP4	1.01e-04	3	122	2	GO:0034455
GeneOntologyCellularComponent	cortical cytoskeleton	PCLO MYRIP ACTN4 IQGAP1 TRPV4 PPP1R9B	1.11e-04	129	122	6	GO:0030863
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYRIP ACTN4 IQGAP1 TRPV4 PPP1R9B	2.15e-04	93	122	5	GO:0030864
GeneOntologyCellularComponent	perinuclear region of cytoplasm	RGPD2 PDE2A PDE4A TRPC7 MYO9B PCLO RGPD1 MYRIP EXOC3 ACTN4 CERT1 EPG5 NEDD4 PDE8B PATJ	3.58e-04	934	122	15	GO:0048471
GeneOntologyCellularComponent	axonemal central apparatus	SPAG6 HYDIN	4.99e-04	6	122	2	GO:1990716
GeneOntologyCellularComponent	growth cone	PCLO EXOC3 GRIN1 IQGAP1 TRPV4 PPP1R9B PCDH9	5.96e-04	245	122	7	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	PCLO EXOC3 GRIN1 IQGAP1 TRPV4 PPP1R9B PCDH9	7.20e-04	253	122	7	GO:0030427
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD2 RGPD1	9.24e-04	8	122	2	GO:1990723
GeneOntologyCellularComponent	neuron projection membrane	TRPV1 GRIN1 PPP1R9B CLRN2	1.36e-03	82	122	4	GO:0032589
GeneOntologyCellularComponent	leading edge membrane	TRPV1 PDE4A GRIN1 TRPV4 PPP1R9B CLRN2	1.47e-03	210	122	6	GO:0031256
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD2 RGPD1	1.47e-03	10	122	2	GO:0044614
GeneOntologyCellularComponent	anchoring junction	CARMIL2 CNTNAP1 OBSCN ACTN4 BCAR1 IQGAP1 NECTIN2 TLN2 TRPV4 PPP1R9B PATJ PCDH9 IQGAP3 NOTCH1	1.68e-03	976	122	14	GO:0070161
GeneOntologyCellularComponent	actin cytoskeleton	CARMIL2 IQGAP2 MYO9B MYRIP ACTN4 BCAR1 IQGAP1 TLN2 TRPV4 PPP1R9B	2.04e-03	576	122	10	GO:0015629
GeneOntologyCellularComponent	cell-cell contact zone	OBSCN NECTIN2 TLN2 PCDH9	2.25e-03	94	122	4	GO:0044291
Domain	-	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	8.02e-11	248	122	15	1.25.40.20
Domain	ANK	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	9.50e-11	251	122	15	SM00248
Domain	ANK_REPEAT	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	1.06e-10	253	122	15	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	1.12e-10	254	122	15	IPR020683
Domain	ANK_REP_REGION	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	1.12e-10	254	122	15	PS50297
Domain	Ank_2	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV3 NOTCH1 INVS ANKRD16	1.34e-10	215	122	14	PF12796
Domain	Ankyrin_rpt	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	1.73e-10	262	122	15	IPR002110
Domain	Ank	ANKRD31 TRPV1 ANKFY1 TRPC7 ASZ1 ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	2.92e-10	228	122	14	PF00023
Domain	RasGAP_C	IQGAP2 IQGAP1 IQGAP3	2.72e-07	3	122	3	IPR000593
Domain	RasGAP_C	IQGAP2 IQGAP1 IQGAP3	2.72e-07	3	122	3	PF03836
Domain	TRPV1-4_channel	TRPV1 TRPV4 TRPV3	1.08e-06	4	122	3	IPR008347
Domain	IQ	IQGAP2 MYO9B OBSCN IQGAP1 IQGAP3 INVS	6.95e-06	71	122	6	PF00612
Domain	IQ	IQGAP2 MYO9B OBSCN IQGAP1 IQGAP3 INVS	1.49e-05	81	122	6	SM00015
Domain	IQ_motif_EF-hand-BS	IQGAP2 MYO9B OBSCN IQGAP1 IQGAP3 INVS	2.73e-05	90	122	6	IPR000048
Domain	IQ	IQGAP2 MYO9B OBSCN IQGAP1 IQGAP3 INVS	3.29e-05	93	122	6	PS50096
Domain	Med12	MED12L MED12	4.23e-05	2	122	2	PF09497
Domain	Mediator_Med12_catenin-bd	MED12L MED12	4.23e-05	2	122	2	IPR021989
Domain	Med12-PQL	MED12L MED12	4.23e-05	2	122	2	PF12144
Domain	Med12-LCEWAV	MED12L MED12	4.23e-05	2	122	2	PF12145
Domain	Med12	MED12L MED12	4.23e-05	2	122	2	SM01281
Domain	Mediator_Med12	MED12L MED12	4.23e-05	2	122	2	IPR019035
Domain	TRPV4_channel	TRPV1 TRPV4	4.23e-05	2	122	2	IPR008348
Domain	Mediator_Med12_LCEWAV	MED12L MED12	4.23e-05	2	122	2	IPR021990
Domain	TRP_channel	TRPV1 TRPC7 TRPV4	4.32e-05	11	122	3	IPR004729
Domain	RasGAP	IQGAP2 IQGAP1 IQGAP3	9.39e-05	14	122	3	SM00323
Domain	RasGAP_CS	IQGAP2 IQGAP1 IQGAP3	9.39e-05	14	122	3	IPR023152
Domain	-	IQGAP2 ACTN4 IQGAP1 CEP95 IQGAP3	1.01e-04	71	122	5	1.10.418.10
Domain	RasGAP	IQGAP2 IQGAP1 IQGAP3	1.17e-04	15	122	3	PF00616
Domain	RAS_GTPASE_ACTIV_1	IQGAP2 IQGAP1 IQGAP3	1.17e-04	15	122	3	PS00509
Domain	RAS_GTPASE_ACTIV_2	IQGAP2 IQGAP1 IQGAP3	1.17e-04	15	122	3	PS50018
Domain	CH-domain	IQGAP2 ACTN4 IQGAP1 CEP95 IQGAP3	1.31e-04	75	122	5	IPR001715
Domain	-	IQGAP2 IQGAP1 IQGAP3	1.43e-04	16	122	3	1.10.506.10
Domain	RasGAP_dom	IQGAP2 IQGAP1 IQGAP3	2.07e-04	18	122	3	IPR001936
Domain	PDEase	PDE2A PDE4A PDE8B	2.44e-04	19	122	3	IPR023088
Domain	PDEase_I	PDE2A PDE4A PDE8B	3.32e-04	21	122	3	PF00233
Domain	PDEASE_I	PDE2A PDE4A PDE8B	3.32e-04	21	122	3	PS00126
Domain	PDEase_CS	PDE2A PDE4A PDE8B	3.32e-04	21	122	3	IPR023174
Domain	-	PDE2A PDE4A PDE8B	3.82e-04	22	122	3	1.10.1300.10
Domain	PDEase_catalytic_dom	PDE2A PDE4A PDE8B	4.38e-04	23	122	3	IPR002073
Domain	HD/PDEase_dom	PDE2A PDE4A PDE8B	4.98e-04	24	122	3	IPR003607
Domain	HDc	PDE2A PDE4A PDE8B	4.98e-04	24	122	3	SM00471
Domain	SEFIR	IL17RC IL17RA	6.24e-04	6	122	2	PF08357
Domain	SEFIR_dom	IL17RC IL17RA	6.24e-04	6	122	2	IPR013568
Domain	SEFIR	IL17RC IL17RA	6.24e-04	6	122	2	PS51534
Domain	CH	IQGAP2 ACTN4 IQGAP1 IQGAP3	8.63e-04	65	122	4	SM00033
Domain	Rab_bind	RGPD2 RGPD1	8.70e-04	7	122	2	PF16704
Domain	GCC2_Rab_bind	RGPD2 RGPD1	8.70e-04	7	122	2	IPR032023
Domain	CH	IQGAP2 ACTN4 IQGAP1 IQGAP3	1.14e-03	70	122	4	PF00307
Domain	CH	IQGAP2 ACTN4 IQGAP1 IQGAP3	1.33e-03	73	122	4	PS50021
Domain	-	RGPD2 RGPD1	1.84e-03	10	122	2	1.10.220.60
Domain	Grip	RGPD2 RGPD1	2.24e-03	11	122	2	SM00755
Domain	GRIP	RGPD2 RGPD1	2.24e-03	11	122	2	PF01465
Domain	ZF_FYVE	ANKFY1 MYRIP FGD6	2.25e-03	40	122	3	PS50178
Domain	ARM	RAP1GDS1 SPAG6 INSC	2.25e-03	40	122	3	SM00185
Domain	Rho_GTPase_activation_prot	IQGAP2 MYO9B IQGAP1 IQGAP3	2.65e-03	88	122	4	IPR008936
Domain	Ran_BP1	RGPD2 RGPD1	2.68e-03	12	122	2	PF00638
Domain	RANBD1	RGPD2 RGPD1	2.68e-03	12	122	2	PS50196
Domain	GRIP_dom	RGPD2 RGPD1	2.68e-03	12	122	2	IPR000237
Domain	GRIP	RGPD2 RGPD1	2.68e-03	12	122	2	PS50913
Domain	RanBD	RGPD2 RGPD1	3.15e-03	13	122	2	SM00160
Domain	Ran_bind_dom	RGPD2 RGPD1	3.15e-03	13	122	2	IPR000156
Domain	START	CERT1 ACOT11	3.15e-03	13	122	2	SM00234
Domain	Armadillo	RAP1GDS1 SPAG6 INSC	3.58e-03	47	122	3	IPR000225
Domain	DEATH-like_dom	HMBOX1 MEFV NFKB1 NLRP4	4.05e-03	99	122	4	IPR011029
Domain	START_lipid-bd_dom	CERT1 ACOT11	4.20e-03	15	122	2	IPR002913
Domain	START	CERT1 ACOT11	4.20e-03	15	122	2	PF01852
Domain	START	CERT1 ACOT11	4.20e-03	15	122	2	PS50848
Domain	WW_DOMAIN_1	IQGAP2 IQGAP1 NEDD4	4.51e-03	51	122	3	PS01159
Domain	WW_DOMAIN_2	IQGAP2 IQGAP1 NEDD4	4.51e-03	51	122	3	PS50020
Domain	WW_dom	IQGAP2 IQGAP1 NEDD4	4.76e-03	52	122	3	IPR001202
Domain	Syntaxin/epimorphin_CS	STX5 STX17	4.78e-03	16	122	2	IPR006012
Domain	SYNTAXIN	STX5 STX17	4.78e-03	16	122	2	PS00914
Domain	Lig_chan-Glu_bd	GRID1 GRIN1	6.05e-03	18	122	2	PF10613
Domain	Glu/Gly-bd	GRID1 GRIN1	6.05e-03	18	122	2	IPR019594
Domain	Lig_chan-Glu_bd	GRID1 GRIN1	6.05e-03	18	122	2	SM00918
Domain	Iontro_rcpt	GRID1 GRIN1	6.05e-03	18	122	2	IPR001320
Domain	Iono_rcpt_met	GRID1 GRIN1	6.05e-03	18	122	2	IPR001508
Domain	Lig_chan	GRID1 GRIN1	6.05e-03	18	122	2	PF00060
Domain	PBPe	GRID1 GRIN1	6.05e-03	18	122	2	SM00079
Pathway	REACTOME_TRP_CHANNELS	TRPV1 TRPC7 TRPV4 TRPV3	3.36e-05	28	94	4	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPV1 TRPC7 TRPV4 TRPV3	3.36e-05	28	94	4	M27241
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS	IQGAP2 CLIP1 IQGAP1 IQGAP3	3.88e-05	29	94	4	MM15219
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS	IQGAP2 CLIP1 IQGAP1 IQGAP3	5.78e-05	32	94	4	M27491
Pubmed	The biology of IQGAP proteins: beyond the cytoskeleton.	IQGAP2 IQGAP1 IQGAP3	4.42e-08	3	124	3	25722290
Pubmed	Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.	IQGAP2 IQGAP1 IQGAP3	4.42e-08	3	124	3	25229330
Pubmed	IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.	IQGAP2 IQGAP1 IQGAP3	4.42e-08	3	124	3	22493426
Pubmed	Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice.	TRPV1 TRPV4 TRPV3	4.42e-08	3	124	3	23536486
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	HMBOX1 EXOSC9 ZNF143 NRF1 IQGAP2 EXOC3 ACTN4 MSH2 CLIP1 IQGAP1 ZFP36L2 NFKB1 NECTIN2 UQCRC2 FGD6 PCDH9 IMMT IQGAP3 INVS KIF2C	4.75e-08	1321	124	20	27173435
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPP2 RGPD2 PDE2A PDE4A CAD ANKFY1 NOP56 IQGAP2 CNTNAP1 RGPD1 GRIN1 CLIP1 IQGAP1 NEDD4 TLN2 PPP1R9B KIF2C	6.19e-08	963	124	17	28671696
Pubmed	Quantitative Real-Time PCR detection of TRPV1-4 gene expression in human leukocytes from healthy and hyposensitive subjects.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	18983665
Pubmed	Expression of transient receptor potential vanilloid (TRPV) families 1, 2, 3 and 4 in the mouse olfactory epithelium.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	19839244
Pubmed	Nicotinic acid is a common regulator of heat-sensing TRPV1-4 ion channels.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	25752528
Pubmed	Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.	IQGAP2 IQGAP1 IQGAP3	1.76e-07	4	124	3	28970065
Pubmed	Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	17521436
Pubmed	Dissecting domain-specific evolutionary pressure profiles of transient receptor potential vanilloid subfamily members 1 to 4.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	25333484
Pubmed	Functional expression of transient receptor potential vanilloid-related channels in chronically hypoxic human pulmonary arterial smooth muscle cells.	TRPV1 TRPV4 TRPV3	1.76e-07	4	124	3	18787888
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TPP2 EXOSC9 CAD NOP56 IQGAP2 NOL11 MSH2 IQGAP1 UTP4 CTNNBL1 TIMELESS UQCRC2 GMPPB IQGAP3	2.39e-07	704	124	14	29955894
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PDE2A PDE4A NRF1 MYO9B OBSCN LAMA5 EML2 GRID1 SMG5 FANCA ZFP36L2 C19orf44 TLN2 IQGAP3 MED12 NOTCH1 ANKRD16	4.29e-07	1105	124	17	35748872
Pubmed	TRPV3 is a temperature-sensitive vanilloid receptor-like protein.	TRPV1 TRPV4 TRPV3	4.40e-07	5	124	3	12077606
Pubmed	Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior.	TRPV1 TRPV4 TRPV3	4.40e-07	5	124	3	30842533
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EXOSC9 CAD ANKFY1 NOP56 PCLO NOL11 ACTN4 MSH2 IQGAP1 MTHFD1 UCHL1 UTP4 CTNNBL1 TLN2 ATM UQCRC2 IMMT IQGAP3 MGAM2	7.37e-07	1425	124	19	30948266
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	IQGAP2 PCLO CNTNAP1 ACTN4 GRIN1 IQGAP1 NEDD4 TLN2 PPP1R9B	8.14e-07	281	124	9	28706196
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	CHL1 ACADS AKNAD1 MSH2 CLIP1 CEP95 TLN2 IQGAP3	8.69e-07	208	124	8	33230847
Pubmed	Th17-associated cytokines promote human airway smooth muscle cell proliferation.	IL17RC NFKB1 IL17RA	8.78e-07	6	124	3	22898922
Pubmed	Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.	TRPV1 TRPV4 TRPV3	1.53e-06	7	124	3	18701070
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPV1 TRPC7 TRPV4 TRPV3	1.55e-06	24	124	4	33884443
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPV1 TRPC7 TRPV4 TRPV3	1.84e-06	25	124	4	16382100
Pubmed	An introduction to TRP channels.	TRPV1 TRPC7 TRPV4 TRPV3	2.53e-06	27	124	4	16460286
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EXOSC9 PDE2A RAP1GDS1 PEG3 CNTNAP1 ANKRD49 MYRIP ZBTB47 BRCC3 ACTN4 SMG5 IQGAP1 ZNF512B TLN2 ATM PBX3 IMMT	3.33e-06	1285	124	17	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 PDE2A CAD RAP1GDS1 CARMIL2 IQGAP2 IGHV1-69-2 PCLO CNTNAP1 ACTN4 GRIN1 IQGAP1 MTHFD1 UCHL1 TLN2 PPP1R9B UQCRC2 IMMT	3.37e-06	1431	124	18	37142655
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EXOSC9 CAD NOP56 MYO9B NOL11 EXOC3 ACTN4 MSH2 IQGAP1 ZNF512B MTHFD1 UCHL1 UTP4 UQCRC2 IMMT	3.93e-06	1024	124	15	24711643
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPP2 CAD EXOC3 BRCC3 ACTN4 MSH2 SIX4 BCAR1 ZNF512B NFKB1 NECTIN2 PPP1R9B UQCRC2 STX17 NOTCH1	5.25e-06	1049	124	15	27880917
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPV1 TRPC7 TRPV4 TRPV3	5.81e-06	33	124	4	19834762
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CAD ANKFY1 NOP56 MYO9B NOL11 EXOC3 ACTN4 MSH2 IQGAP1 MTHFD1 UTP4 CTNNBL1 UQCRC2 GMPPB IMMT MED12 KIF2C	6.57e-06	1353	124	17	29467282
Pubmed	IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.	IQGAP2 IQGAP1 IQGAP3	9.51e-06	12	124	3	18604197
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD2 CNTNAP1 RGPD1	1.23e-05	13	124	3	31427429
Pubmed	Possible involvement of TRPV1 and TRPV4 in nociceptive stimulation- induced nocifensive behavior and neuroendocrine response in mice.	TRPV1 TRPV4	1.26e-05	2	124	2	26314785
Pubmed	Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission.	TRPV1 TRPV4	1.26e-05	2	124	2	29791836
Pubmed	Orphan glutamate receptor delta1 subunit required for high-frequency hearing.	GRID1 GRIN1	1.26e-05	2	124	2	17438141
Pubmed	The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.	TRPV4 TRPV3	1.26e-05	2	124	2	25351988
Pubmed	Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.	TRPV4 TRPV3	1.26e-05	2	124	2	19164517
Pubmed	TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation.	TRPV4 TRPV3	1.26e-05	2	124	2	21586160
Pubmed	Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects.	TRPV1 TRPV4	1.26e-05	2	124	2	29018170
Pubmed	The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells.	TRPV1 TRPV4	1.26e-05	2	124	2	21562271
Pubmed	Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition.	PDE2A PDE4A	1.26e-05	2	124	2	25230992
Pubmed	Dynamic and permissive roles of TRPV1 and TRPV4 channels for thermosensation in mouse supraoptic magnocellular neurosecretory neurons.	TRPV1 TRPV4	1.26e-05	2	124	2	24155319
Pubmed	Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens.	TRPV1 TRPV4	1.26e-05	2	124	2	34884463
Pubmed	Genetic and pharmacological evidence for low-abundance TRPV3 expression in primary vagal afferent neurons.	TRPV1 TRPV3	1.26e-05	2	124	2	26843581
Pubmed	Interaction between NF-κB signaling and Notch signaling in gliogenesis of mouse mesencephalic neural crest cells.	NFKB1 NOTCH1	1.26e-05	2	124	2	21983543
Pubmed	Functional roles of TRPV1 and TRPV4 in control of lower urinary tract activity: dual analysis of behavior and reflex during the micturition cycle.	TRPV1 TRPV4	1.26e-05	2	124	2	25761879
Pubmed	Spinophilin negatively controlled the function of transient receptor potential vanilloid 1 in dorsal root ganglia neurons of mice.	TRPV1 PPP1R9B	1.26e-05	2	124	2	31563651
Pubmed	[Proteasome inhibitor induces apoptosis and influences the expression of Notch1 and NF-kappaB in multiple myeloma RPMI8226 cells].	NFKB1 NOTCH1	1.26e-05	2	124	2	18549623
Pubmed	Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways.	NFKB1 NOTCH1	1.26e-05	2	124	2	21308734
Pubmed	Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4.	TRPV1 TRPV4	1.26e-05	2	124	2	21994383
Pubmed	SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.	TRPV1 TRPV3	1.26e-05	2	124	2	22162417
Pubmed	Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.	TRPV1 TRPV4	1.26e-05	2	124	2	26146187
Pubmed	Acute heat-evoked temperature sensation is impaired but not abolished in mice lacking TRPV1 and TRPV3 channels.	TRPV1 TRPV3	1.26e-05	2	124	2	24925072
Pubmed	Coassembly of Warm Temperature-Sensitive Transient Receptor Potential Vanilloid (TRPV) 3 and TRPV4 Channel Complexes with Distinct Functional Properties.	TRPV4 TRPV3	1.26e-05	2	124	2	35361697
Pubmed	[Transient receptor potential (TRP) channel and cough].	TRPV1 TRPV4	1.26e-05	2	124	2	18552442
Pubmed	TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes.	TRPV4 TRPV3	1.26e-05	2	124	2	15004014
Pubmed	Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis.	FANCA ATM	1.26e-05	2	124	2	18224251
Pubmed	Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis.	ACTN4 UCHL1	1.26e-05	2	124	2	24662305
Pubmed	Increased levels of NOTCH1, NF-kappaB, and other interconnected transcription factors characterize primitive sets of hematopoietic stem cells.	NFKB1 NOTCH1	1.26e-05	2	124	2	19686049
Pubmed	Nuclear factor κB-dependent neurite remodeling is mediated by Notch pathway.	NFKB1 NOTCH1	1.26e-05	2	124	2	21832199
Pubmed	Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.	IQGAP2 IQGAP3	1.26e-05	2	124	2	29073199
Pubmed	Fanconi Anemia and Ataxia Telangiectasia in Siblings who Inherited Unique Combinations of Novel FANCA and ATM Null Mutations.	FANCA ATM	1.26e-05	2	124	2	30339652
Pubmed	Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.	IQGAP2 IQGAP1	1.26e-05	2	124	2	24998570
Pubmed	TRPV1 and TRPV4 channels: potential therapeutic targets for ischemic conditioning-induced cardioprotection.	TRPV1 TRPV4	1.26e-05	2	124	2	25449039
Pubmed	IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood.	IL17RC IL17RA	1.26e-05	2	124	2	18097068
Pubmed	Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain.	NFKB1 NOTCH1	1.26e-05	2	124	2	11418662
Pubmed	Recurrent activations of transient receptor potential vanilloid-1 and vanilloid-4 promote cellular proliferation and migration in esophageal squamous cell carcinoma cells.	TRPV1 TRPV4	1.26e-05	2	124	2	30761248
Pubmed	TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.	TRPV1 TRPV4	1.26e-05	2	124	2	23021218
Pubmed	IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.	IQGAP2 IQGAP1	1.26e-05	2	124	2	20977743
Pubmed	ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.	NRF1 ATM	1.26e-05	2	124	2	30642892
Pubmed	Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma.	TRPV1 TRPV4	1.26e-05	2	124	2	20639579
Pubmed	Osmoregulatory thirst in mice lacking the transient receptor potential vanilloid type 1 (TRPV1) and/or type 4 (TRPV4) receptor.	TRPV1 TRPV4	1.26e-05	2	124	2	25100078
Pubmed	[ALPHA-ACTININS AND SIGNAL TRANSDUCTION PATHWAYS].	ACTN4 NFKB1	1.26e-05	2	124	2	26995963
Pubmed	Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.	IQGAP2 IQGAP1	1.26e-05	2	124	2	18180285
Pubmed	[Notch1 signaling participates in the release of inflammatory mediators in mouse RAW264.7 cells via activating NF-κB pathway].	NFKB1 NOTCH1	1.26e-05	2	124	2	29169413
Pubmed	The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Pneumococcal Nasal Colonization and Subsequent Development of Invasive Disease.	TRPV1 TRPV4	1.26e-05	2	124	2	34804016
Pubmed	Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression.	NFKB1 ATM	1.26e-05	2	124	2	22096476
Pubmed	Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens.	TRPV1 TRPV4	1.26e-05	2	124	2	31229503
Pubmed	DNA Repair Gene Expression Levels as Indicators of Breast Cancer in the Breast Cancer Family Registry.	MSH2 ATM	1.26e-05	2	124	2	27466510
Pubmed	Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.	TRPV1 TRPV4	1.26e-05	2	124	2	25069877
Pubmed	TRPV1 and TRPV4 play pivotal roles in delayed onset muscle soreness.	TRPV1 TRPV4	1.26e-05	2	124	2	23799042
Pubmed	Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling.	NFKB1 NOTCH1	1.26e-05	2	124	2	17604336
Pubmed	Smaller bladder capacity and stronger bladder contractility in patients with ketamine cystitis are associated with elevated TRPV1 and TRPV4.	TRPV1 TRPV4	1.26e-05	2	124	2	33664402
Pubmed	Role of Trpv1 and Trpv4 in surgical incision-induced tissue swelling and Fos-like immunoreactivity in the central nervous system of mice.	TRPV1 TRPV4	1.26e-05	2	124	2	29733975
Pubmed	The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration.	TRPV1 TRPV4	1.26e-05	2	124	2	36870285
Pubmed	Warm temperatures activate TRPV4 in mouse 308 keratinocytes.	TRPV4 TRPV3	1.26e-05	2	124	2	12783886
Pubmed	Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer.	IL17RC IL17RA	1.26e-05	2	124	2	11706037
Pubmed	Changes in transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 in patients with lower urinary tract dysfunction.	TRPV1 TRPV4	1.26e-05	2	124	2	35437956
Pubmed	Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells.	TRPV1 TRPV4	1.26e-05	2	124	2	34445178
Pubmed	Role of TH17 Responses in Increasing Herpetic Keratitis in the Eyes of Mice Infected with HSV-1.	IL17RC IL17RA	1.26e-05	2	124	2	32516406
Pubmed	Notch1 induces cell cycle arrest and apoptosis in human cervical cancer cells: involvement of nuclear factor kappa B inhibition.	NFKB1 NOTCH1	1.26e-05	2	124	2	17316355
Pubmed	Differential localizations of the transient receptor potential channels TRPV4 and TRPV1 in the mouse urinary bladder.	TRPV1 TRPV4	1.26e-05	2	124	2	19029406
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	CAD NOP56 MSH2 IQGAP1 UCHL1 UQCRC2	1.36e-05	144	124	6	35681168
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD2 CAD ACADS PCLO CNTNAP1 RGPD1 ACTN4 GRIN1 STX5 MTHFD1 UCHL1 PITPNM3 TLN2 PPP1R9B UQCRC2	1.39e-05	1139	124	15	36417873
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	TPP2 RAP1GDS1 CNTNAP1 ACTN4 GRIN1 UCHL1 PPP1R9B UQCRC2 IMMT	1.51e-05	403	124	9	30562941
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPV1 TRPC7 TRPV4 TRPV3	1.87e-05	44	124	4	19322198
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 CAD NOL11 ACTN4 MSH2 IQGAP1 UTP4 ATM UQCRC2 IMMT MED12	2.34e-05	653	124	11	22586326
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EXOSC9 CAD NOL11 LAMA5 E4F1 SIX4 IQGAP1 ZFP36L2 MTHFD1 UTP4 CTNNBL1 UQCRC2 PATJ IMMT IQGAP3 MED12 KIF2C	2.41e-05	1497	124	17	31527615
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	CAD NOP56 ACADS LAMA5 ACTN4 IQGAP1 NEDD4 MTHFD1 UCHL1 AHSG UQCRC2 IMMT	3.18e-05	803	124	12	36517590
Interaction	KCNA3 interactions	CHL1 CAD NOP56 ACADS AKNAD1 EXOC3 MSH2 CLIP1 IQGAP1 MTHFD1 CEP95 NECTIN2 TLN2 PATJ IMMT IQGAP3 MED12 NOTCH1 KIF2C	1.37e-06	871	123	19	int:KCNA3
Interaction	AKAP5 interactions	TRPV1 GRIN1 IQGAP1 TRPV4 PPP1R9B TRPV3	1.10e-05	82	123	6	int:AKAP5
Interaction	RGPD2 interactions	RGPD2 RGPD1 EXOC3 CLRN2	2.08e-05	27	123	4	int:RGPD2
Interaction	BRCA1 interactions	HMBOX1 TPP2 CAD NOP56 PEG3 OBSCN ZBTB47 NOL11 BRCC3 MSH2 CLIP1 IQGAP1 FANCA STX5 MTHFD1 UTP4 NFKB1 PPP1R9B ATM MED12 KIF2C	2.08e-05	1249	123	21	int:BRCA1
Interaction	RABEP2 interactions	PPP1R21 RAP1GDS1 EXOC3 BRCC3 CLIP1 ASB7	2.26e-05	93	123	6	int:RABEP2
Interaction	TOP3B interactions	PDE2A PDE4A CAD NRF1 MYO9B OBSCN LAMA5 EML2 GRID1 ACTN4 SMG5 IQGAP1 FANCA ZFP36L2 AHSG C19orf44 TLN2 PPP1R9B IMMT IQGAP3 MED12 NOTCH1 ANKRD16	2.50e-05	1470	123	23	int:TOP3B
Interaction	AGAP2 interactions	IQGAP2 PCLO ACTN4 GRIN1 IQGAP1 NEDD4 TLN2 PPP1R9B	4.49e-05	210	123	8	int:AGAP2
Cytoband	5q13.3	ANKRD31 IQGAP2 CERT1 PDE8B	2.49e-06	35	124	4	5q13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	CARMIL2 CMTM4 ZDHHC1 UTP4 HYDIN	1.46e-04	183	124	5	chr16q22
Cytoband	Xq13	CXCR3 MED12	5.54e-04	13	124	2	Xq13
Cytoband	2p11.2	RGPD2 RGPD1 IMMT	7.10e-04	64	124	3	2p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5q13	ANKRD31 IQGAP2 CERT1 PDE8B	7.96e-04	152	124	4	chr5q13
GeneFamily	Ankyrin repeat domain containing	ANKRD31 TRPV1 ANKFY1 ASZ1 ASPG ANKRD49 ASB12 ASB7 NFKB1 TRPV4 TRPV3 NOTCH1 INVS ANKRD16	1.74e-11	242	91	14	403
GeneFamily	Transient receptor potential cation channels	TRPV1 TRPC7 TRPV4 TRPV3	1.12e-05	28	91	4	249
GeneFamily	Phosphodiesterases	PDE2A PDE4A PDE8B	2.31e-04	24	91	3	681
GeneFamily	StAR related lipid transfer domain containing	CERT1 ACOT11	2.52e-03	15	91	2	759
GeneFamily	Syntaxins	STX5 STX17	2.87e-03	16	91	2	818
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500	CAD ASZ1 NOP56 TDH MSH2 SIX4 UCHL1 UTP4 ATM NLRP4 KIF2C	1.82e-05	396	122	11	gudmap_dev gonad_e13.5_M_GermCell_Oct_500
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MYRIP ACTN4 BCAR1 MMRN2 TRPV4 NOTCH1	6.07e-08	189	124	8	d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MYRIP ACTN4 BCAR1 MMRN2 TRPV4 NOTCH1	6.07e-08	189	124	8	476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MYRIP ACTN4 BCAR1 MMRN2 TRPV4 NOTCH1	6.07e-08	189	124	8	3fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	LRRC32 ZBTB47 GRID1 HSPA12B ZFP36L2 MMRN2 CPXM1	9.91e-07	188	124	7	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	Endothelial\|World / shred by cell class for turbinate	PDE2A LRRC32 MYRIP HSPA12B ABCA8 MMRN2	1.10e-05	179	124	6	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	droplet-Kidney-nan-18m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 HSPA12B UCHL1 MMRN2 TIMELESS	1.46e-05	188	124	6	ca3be1942b179b512ab242acded31f1e3748c753
ToppCell	facs-GAT-Fat-24m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 HSPA12B NECTIN2 MMRN2 NOTCH1	1.55e-05	190	124	6	da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 ACTN4 HSPA12B MMRN2 TIMELESS	1.55e-05	190	124	6	1ff2295c9fc94ea21fff286706b739d0deb032d0
ToppCell	facs-GAT-Fat-24m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 HSPA12B NECTIN2 MMRN2 NOTCH1	1.55e-05	190	124	6	3395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 ACTN4 HSPA12B MMRN2 TIMELESS	1.55e-05	190	124	6	61f2f9fb4b8f47a2a669f6b052214d2ce0c194cd
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC32 MYRIP UCHL1 NECTIN2 MMRN2 TRPV4	1.55e-05	190	124	6	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	facs-GAT-Fat-24m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 HSPA12B NECTIN2 MMRN2 NOTCH1	1.55e-05	190	124	6	e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 ACTN4 HSPA12B MMRN2 TIMELESS	1.55e-05	190	124	6	d415c8f3d69a8142e95307aeabc6d0e812cd5165
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MSH2 FANCA TIMELESS PBX3 IQGAP3 KIF2C	1.55e-05	190	124	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LRRC32 MYRIP HSPA12B MMRN2 TRPV4 NOTCH1	1.59e-05	191	124	6	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 BCAR1 HSPA12B NECTIN2 MMRN2	1.64e-05	192	124	6	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSAD1 DEAF1 LRRC32 LAMA5 MMRN2 PBX3	1.79e-05	195	124	6	6a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCell	facs-GAT-Fat-3m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 BCAR1 HSPA12B NECTIN2 MMRN2	1.85e-05	196	124	6	b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCell	facs-GAT-Fat-3m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 BCAR1 HSPA12B NECTIN2 MMRN2	1.85e-05	196	124	6	ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCell	facs-GAT-Fat-3m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LAMA5 BCAR1 HSPA12B NECTIN2 MMRN2	1.85e-05	196	124	6	039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 JPH2 LAMA5 MED12L PATJ PCDH9	1.85e-05	196	124	6	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	1.90e-05	197	124	6	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	1.90e-05	197	124	6	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 BCAR1 HSPA12B NECTIN2 MMRN2	1.95e-05	198	124	6	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDE2A MYRIP LAMA5 BCAR1 HSPA12B MMRN2	1.95e-05	198	124	6	122215d9288533ad03562cf777e846504863df9a
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDE2A MYRIP LAMA5 BCAR1 HSPA12B MMRN2	1.95e-05	198	124	6	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ABCA8 INSC UCHL1 PCDH9 NOTCH1	1.95e-05	198	124	6	c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 BCAR1 HSPA12B NECTIN2 MMRN2	1.95e-05	198	124	6	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	10x3'2.3-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	2.01e-05	199	124	6	41f046646fff65b7e51b63d3204f76ef32054781
ToppCell	Control-Control-Others-HSPC\|Control / Disease, condition lineage and cell class	SPAG6 NEDD4 UCHL1 MED12L CPXM1 PCDH9	2.01e-05	199	124	6	b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ABCA8 INSC UCHL1 PCDH9 NOTCH1	2.01e-05	199	124	6	8d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	2.01e-05	199	124	6	ef7f7f7c861827574b120f48cf4052c563929081
ToppCell	10x5'v1-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	2.07e-05	200	124	6	2488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	2.07e-05	200	124	6	ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell	10x5'v1-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A LRRC32 MYRIP BCAR1 NECTIN2 MMRN2	2.07e-05	200	124	6	e786544cf6f891550c4be55ebb4928c92297b504
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ABCA8 INSC UCHL1 PCDH9 NOTCH1	2.07e-05	200	124	6	553e9612874480f4d2a45671462e266cd0a09321
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM3 PARP9 IQGAP3 NOTCH1 KIF2C	3.31e-05	131	124	5	419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|normal_Lung / Location, Cell class and cell subclass	NOL11 ZFP36L2 WNT10A TRPV4 INVS	1.02e-04	166	124	5	ff32422390852546e0cb216192452e9c47bd9509
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPG LRRC32 MYRIP TRPV4 PCDH9	1.05e-04	167	124	5	f01b96173deda0239fa482989873cf308e49d48c
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPG LRRC32 MYRIP TRPV4 PCDH9	1.05e-04	167	124	5	5fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell	3'_v3-blood-Hematopoietic_progenitors-HSC-MPP\|blood / Manually curated celltypes from each tissue	PCLO UCHL1 MED12L CPXM1 PCDH9	1.14e-04	170	124	5	1443d7fccc81088dd42dcbb9361e269872542274
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	PDE2A PEG3 JPH2 ABCA8 PDE8B	1.14e-04	170	124	5	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	PDE2A PEG3 JPH2 ABCA8 PDE8B	1.14e-04	170	124	5	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	PDE2A PEG3 JPH2 ABCA8 PDE8B	1.14e-04	170	124	5	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	EXOSC9 PATJ HBM PCDH9 ANKRD16	1.17e-04	171	124	5	78491478ba65bad45238fe114f5251b2adea323d
ToppCell	Lymphoid-Lymphoid-B_cells_(cycle)\|Lymphoid / shred on cell class and cell subclass (v4)	PDE4A NOP56 WNT10A ATP11C KIF2C	1.20e-04	172	124	5	f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO GRIN1 FANCA ACOT11 PITPNM3	1.27e-04	174	124	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.27e-04	174	124	5	ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.27e-04	174	124	5	d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.27e-04	174	124	5	2453419842fd22d066631615403393bfe4449bb8
ToppCell	wk_20-22-Hematologic-Myeloid-Promonocyte-like\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TRPV1 MEFV IL17RA IQGAP3 KIF2C	1.30e-04	175	124	5	654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CXCR3 ANKRD49 ZFP36L2 ACOT11 ATP11C	1.30e-04	175	124	5	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.30e-04	175	124	5	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.30e-04	175	124	5	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CXCR3 MED12L WNT10A NLRP4 PCDH9	1.30e-04	175	124	5	9d6135e183179968555670abec39dff9da2c3219
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RGPD2 PDE4A ZFY ACOT11 UQCRC2	1.34e-04	176	124	5	581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 BCAR1 HSPA12B UCHL1 MMRN2	1.34e-04	176	124	5	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	Control-Lymphoid-pDC\|Control / Condition, Lineage and Cell class	CXCR3 CNTNAP1 MED12L ASPRV1 PCDH9	1.34e-04	176	124	5	5de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 BCAR1 HSPA12B UCHL1 MMRN2	1.34e-04	176	124	5	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	PBMC-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	CXCR3 CARMIL2 LAMA5 PATJ FGD6	1.37e-04	177	124	5	974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell	3'_v3-blood-Hematopoietic_progenitors\|blood / Manually curated celltypes from each tissue	PCLO UCHL1 MED12L CPXM1 PCDH9	1.37e-04	177	124	5	22c77077951889e63489abfabf90900655655c82
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ZDHHC1 UCHL1 MMRN2 TLN2	1.45e-04	179	124	5	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	CXCR3 PDE4A STX5 UTP4 CTNNBL1	1.45e-04	179	124	5	c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCell	facs-Skin-Anagen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 TDH IL17RC CLIP1 ASPRV1	1.45e-04	179	124	5	4a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ABCA8 INSC UCHL1 NOTCH1	1.52e-04	181	124	5	f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 ACTN4 AHSG MMRN2	1.56e-04	182	124	5	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA5 IL17RC ZDHHC1 UCHL1 HYDIN	1.60e-04	183	124	5	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	Basal\|World / shred by cell class for mouse tongue	LAMA5 NEDD4 MTHFD1 WNT10A TRPV4	1.60e-04	183	124	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE2A MYRIP LAMA5 HSPA12B MMRN2	1.60e-04	183	124	5	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO OBSCN GRID1 TLN2 HYDIN	1.65e-04	184	124	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	CMTM4 PEG3 ZBTB47 CPXM1 TRPV4	1.65e-04	184	124	5	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO OBSCN GRID1 TLN2 HYDIN	1.65e-04	184	124	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO OBSCN GRID1 TLN2 HYDIN	1.65e-04	184	124	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	lymphoid-NK_cell-TNFRSF18+IL7R-_NK_cell\|lymphoid / Lineage, cell class and subclass	CXCR3 ACTN4 INSC MMRN2 HBM	1.65e-04	184	124	5	62a3918705a3fcf3ef25c9ceb80f575a2e56ef76
ToppCell	droplet-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	1d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCell	droplet-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	76caad53d55fff5acca27bf190a6de7b27437d9f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	1fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE2A LRRC32 MMRN2 TIMELESS NOTCH1	1.65e-04	184	124	5	2467207aaea307873ab286f89cfc7668a227a694
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	LRRC32 CNTNAP1 GRID1 HSPA12B CPXM1	1.69e-04	185	124	5	e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	PDE2A LRRC32 MYRIP HSPA12B MMRN2	1.69e-04	185	124	5	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 MYRIP HSPA12B MMRN2 PCDH9	1.69e-04	185	124	5	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HMBOX1 PDE2A GRID1 HSD3B7 MMRN2	1.69e-04	185	124	5	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	Endothelial-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	PDE2A LRRC32 MYRIP HSPA12B MMRN2	1.69e-04	185	124	5	dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LRRC32 MYRIP HSPA12B NEDD4 MMRN2	1.69e-04	185	124	5	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 PCLO CNTNAP1 PITPNM3 PATJ	1.73e-04	186	124	5	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	COVID-19_Convalescent-PLT_4\|World / Disease Group and Platelet Clusters	HMBOX1 LRRC32 CNTD1 ZNHIT2 FGD6	1.73e-04	186	124	5	5954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ABCA8 UCHL1 CPXM1 TLN2 ANKRD16	1.73e-04	186	124	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	Endothelial-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	PDE2A LRRC32 MYRIP HSPA12B MMRN2	1.73e-04	186	124	5	796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RSAD1 CAD CPXM1 NOTCH1	1.73e-04	186	124	5	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	ABCA8 UCHL1 CPXM1 TLN2 ANKRD16	1.73e-04	186	124	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RSAD1 CAD CPXM1 NOTCH1	1.73e-04	186	124	5	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RSAD1 CAD CPXM1 NOTCH1	1.73e-04	186	124	5	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ABCA8 INSC UCHL1 NOTCH1	1.73e-04	186	124	5	76535681667c8afb884fa72b6edfee9e1e46335b
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA8 INSC UCHL1 PCDH9 NOTCH1	1.77e-04	187	124	5	dfc2b95d70daf533bc0cc4ce78af9f65dd75a25b
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A LRRC32 UCHL1 MMRN2 NOTCH1	1.77e-04	187	124	5	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 HMBOX1 EXOC3 INSC PCDH9	1.77e-04	187	124	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RGPD1 LAMA5 IQGAP1 CPXM1 FGD6	1.77e-04	187	124	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 PCLO CNTNAP1 PITPNM3 PATJ	1.77e-04	187	124	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
Drug	CID5148062	TRPV1 NFKB1 TRPV4 TRPV3	3.76e-07	12	122	4	CID005148062
Drug	PPAHV	TRPV1 TRPV4 TRPV3	1.49e-06	5	122	3	CID003035862
Drug	drimanial	TRPV1 TRPV4 TRPV3	2.97e-06	6	122	3	CID000636975
Drug	phorbol-12,13-dibenzoate	TRPV1 TRPV4 TRPV3 ASPRV1	3.56e-06	20	122	4	CID000072294
Drug	isovelleral	TRPV1 TRPV4 TRPV3	5.17e-06	7	122	3	CID000037839
Drug	Iobenguane sulfate; Up 200; 10.8uM; HL60; HG-U133A	TRPV1 CAD CNTNAP1 EML2 NECTIN2 TLN2 TIMELESS NOTCH1	1.22e-05	199	122	8	1729_UP
Disease	Bladder Neoplasm	TRPV1 ANKFY1 FANCA NECTIN2 ATM NOTCH1	2.52e-05	140	121	6	C0005695
Disease	Malignant neoplasm of urinary bladder	TRPV1 ANKFY1 FANCA NECTIN2 ATM NOTCH1	2.62e-05	141	121	6	C0005684
Disease	Colorectal Carcinoma	CHL1 CAD PEG3 OBSCN EML2 GRID1 MSH2 ABCA8 ZFP36L2 MMRN2 ATP11C UQCRC2	3.30e-05	702	121	12	C0009402
Disease	Malignant neoplasm of breast	PDE2A OBSCN SIX4 BCAR1 SPAG6 CLIP1 EPG5 NEDD4 STX5 NECTIN2 TIMELESS ATM ZNHIT2 MED12 NOTCH1	3.48e-05	1074	121	15	C0006142
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	WNT10A ATM NOTCH1	3.62e-05	16	121	3	C0334634
Disease	Bipolar Disorder	PDE4A TRPC7 ACADS PCLO GRID1 GRIN1 NEDD4 MTHFD1 TIMELESS	1.60e-04	477	121	9	C0005586
Disease	Candidiasis, Chronic Mucocutaneous	IL17RC IL17RA	2.47e-04	6	121	2	C0006845
Disease	Mental Depression	PDE4A DEAF1 PCLO GRID1 TIMELESS MED12	6.46e-04	254	121	6	C0011570
Disease	Peripheral T-Cell Lymphoma	NECTIN2 ATM	7.35e-04	10	121	2	C0079774
Disease	Alopecia Areata	CXCR3 STX17	7.35e-04	10	121	2	C0002171
Disease	apolipoprotein B to apolipoprotein A1 ratio	CERT1 ABCA8 NECTIN2	1.08e-03	49	121	3	EFO_0021897
Disease	Liver carcinoma	IQGAP2 ASPG IQGAP1 UCHL1 PITPNM3 ATM IQGAP3 KIF2C	1.19e-03	507	121	8	C2239176
Disease	Depressive disorder	PDE4A DEAF1 PCLO GRID1 TIMELESS MED12	1.26e-03	289	121	6	C0011581
Disease	alcohol and nicotine codependence	RGPD2 RGPD1	1.26e-03	13	121	2	EFO_0004776
Disease	colorectal cancer (is_implicated_in)	MSH2 CTNNBL1 TRPV3 ATM	1.58e-03	121	121	4	DOID:9256 (is_implicated_in)
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM NOTCH1	1.69e-03	15	121	2	C0496930
Disease	Benign neoplasm of bladder	ATM NOTCH1	1.69e-03	15	121	2	C0154017
Disease	Carcinoma in situ of bladder	ATM NOTCH1	1.69e-03	15	121	2	C0154091
Disease	Abnormal behavior	MED12L TRPV4	1.93e-03	16	121	2	C0233514
Disease	Pontoneocerebellar hypoplasia	EXOSC9 PCLO	1.93e-03	16	121	2	cv:C1261175
Disease	response to opioid	MSH2 PBX3 PCDH9	2.04e-03	61	121	3	EFO_0008541
Disease	Carcinoma of bladder	ATM NOTCH1	2.44e-03	18	121	2	C0699885
Disease	corneal resistance factor	DEAF1 EXOC3 ABCA8 NEDD4 WNT10A CPXM1 XYLB	2.64e-03	451	121	7	EFO_0010067
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MSH2 ATM	2.72e-03	19	121	2	C2936783
Disease	dentures	WNT10A PBX3 MED12	3.01e-03	70	121	3	EFO_0010078
Disease	dental caries, dentures	WNT10A PBX3 MED12	3.01e-03	70	121	3	EFO_0003819, EFO_0010078
Disease	Adenocarcinoma of prostate	FANCA ATM	3.02e-03	20	121	2	C0007112
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ANKRD31 CERT1 ABCA8 NECTIN2 AHSG	3.10e-03	239	121	5	EFO_0008317, EFO_0020945
Disease	breast cancer (is_implicated_in)	MSH2 FANCA NFKB1 ATM	3.44e-03	150	121	4	DOID:1612 (is_implicated_in)
Disease	tooth agenesis	NOL11 WNT10A	3.65e-03	22	121	2	EFO_0005410
Disease	reticulocyte count	PPP1R21 ACADS IQGAP2 MYO9B CLIP1 ZFP36L2 NFKB1 TLN2 ASPRV1 HBM MED12	3.85e-03	1045	121	11	EFO_0007986
Disease	platelet-to-lymphocyte ratio	EXOSC9 PDE4A IQGAP2 IQGAP1 MED12L C19orf44	3.91e-03	363	121	6	EFO_0008446
Disease	Prostatic Neoplasms	ASZ1 IL17RC BCAR1 ZFP36L2 NECTIN2 ATM PATJ MED12	3.95e-03	616	121	8	C0033578
Disease	Malignant neoplasm of prostate	ASZ1 IL17RC BCAR1 ZFP36L2 NECTIN2 ATM PATJ MED12	3.95e-03	616	121	8	C0376358
Disease	Immunologic Deficiency Syndromes	EPG5 ATM	3.99e-03	23	121	2	C0021051
Disease	reticulocyte measurement	ACADS IQGAP2 MYO9B ACTN4 CLIP1 ZFP36L2 NFKB1 TLN2 ASPRV1 HBM MED12	4.08e-03	1053	121	11	EFO_0010700

Protein segments in the cluster

Peptide	Gene	Start	Entry
SDHQVLNDAEVAALL	CXCR3	6	P49682
EAAVHAENLITALVN	EPG5	1641	Q9HCE0
AQENHAVISIDDVEG	CNTNAP1	451	P78357
LQIQAAVAAGDVHTV	ASB7	16	Q9H672
QALHRAAVTGQDEAI	ANKRD16	241	Q6P6B7
GHDNTDVSIAVVDLL	CTNNBL1	151	Q8WYA6
AASEAATAISHQAIQ	ACADS	351	P16219
AAVAAVQSAVHELLE	BCAR1	506	P56945
TAIQGDVTQAHEVAA	HSD3B7	61	Q9H2F3
DVTQAHEVAAAVAGA	HSD3B7	66	Q9H2F3
VAALEQLAQHVAAAI	CARMIL2	101	Q6F5E8
ASNSVILHLDVGDEV	C1QL4	196	Q86Z23
SDLAAHQDRVEQIAA	ACTN4	461	O43707
AVIAVDGINHDVTTA	CPXM1	641	Q96SM3
VVHVDAAQAFLLLSD	ACOT11	431	Q8WXI4
AARDGHTQVVALLVA	ASZ1	156	Q8WWH4
ALLVAHGAEVNTQDE	ASZ1	166	Q8WWH4
LANELSVDEAALHAA	IQGAP1	206	P46940
SVDEAALHAAVIAIN	IQGAP1	211	P46940
AEANAFSVLQHVLGA	UQCRC2	281	P22695
DLTTHAVDAVVNAAN	PARP9	126	Q8IXQ6
AVDAVVNAANEDLLH	PARP9	131	Q8IXQ6
NGVALTALDQDHVAV	NOL11	261	Q9H8H0
ENFHVVETLADNAII	CERT1	476	Q9Y5P4
NISETASVLAENAAH	ANKRD31	1586	Q8N7Z5
AAVDENGNNALHLAV	ANKFY1	966	Q9P2R3
TAVTAAHAVAAAVQN	PBX3	311	P40426
HTLVLAAEEGALVAA	IL17RA	666	Q96F46
LENANAVSEGVVHED	NOP56	61	O00567
VEHSVEGAQRAAAIA	JPH2	366	Q9BR39
HAAVSADAQGVFQIL	NOTCH1	1966	P46531
AAHNSIEVGAVFAVL	MED12L	1166	Q86YW9
AVVDNELNAVNDGHL	NEDD4	126	P46934
VHGTILANANIDVVD	CHL1	406	O00533
VSHENINLVDGIADA	MGAM2	151	Q2M2H8
SALHVAEAAGNLAVV	ASPG	536	Q86U10
LQNAVDAVSLAVDAH	MMRN2	536	Q9H8L6
QVLLAHGADVDSLDV	ASB12	81	Q8WXK4
LVNHAVAQNEEGDAA	ECHDC2	206	Q86YB7
HQVEALAAAGVDHVI	GMPPB	36	Q9Y5P6
HNILIATSVADEGID	DDX58	691	O95786
ANIEAAILESHGIDV	HMBOX1	341	Q6NT76
HDGNIIDAASIAAIV	EXOSC9	141	Q06265
QTHLEDAGAAIAAAE	PCLO	4906	Q9Y6V0
HFNELEASVVVQDVA	MKNK2	176	Q9HBH9
VIQLHATDADIGSNA	PCDH9	271	Q9HC56
ADKEAGAVAAVILVH	PDE2A	151	O00408
STAAEVEAQREHQAA	PDE4A	841	P27815
DQLDEVAALIAATVH	PDE8B	641	O95263
LNSEAAAHAVATLAE	NRF1	406	Q16656
AAHAVATLAEATLQG	NRF1	411	Q16656
LRGIEQAVQSHAVAE	IMMT	546	Q16891
HLLAASQNRIVDGAV	MED12	1206	Q93074
ANFHIIDNVDLVVSA	NLRP4	576	Q96MN2
IGAQAHAVNVILDAE	MEFV	591	O15553
ELIAQGADVHAVTVD	ANKRD49	126	Q8WVL7
ANEDARQEVGVAVHT	LAMA5	1116	O15230
VAAATGTHAEVQLVQ	IGHV1-69-2	11	A0A0G2JMI3
TLETEAAQHQAVVDG	PPP1R21	146	Q6ZMI0
ESAVLQHAVQAALGA	HSPA12B	491	Q96MM6
LANELSVDEAAVHAA	IQGAP3	196	Q86VI3
SVDEAAVHAAVLAIN	IQGAP3	201	Q86VI3
AAAAAAQEVEANVHV	PEG3	1366	Q9GZU2
QVAHSEVQAEAGASA	OBSCN	986	Q5VST9
LAAQLHQGRVDVDAT	LRRC32	581	Q14392
QSAELVHIDLGVAFE	ATM	2881	Q13315
DLVAAALVDHIQFGD	HYDIN	3646	Q4G0P3
GQSAAVTVQADEVHV	DEAF1	541	O75398
NDTRVVHAAKAALAA	AHSG	156	P02765
PIANHVISADAIEAL	C19orf44	566	Q9H6X5
SAAALHFAIQQVREE	FANCA	1226	O15360
EDGNVTVQHAALSAL	RAP1GDS1	371	P52306
VAAGDSSHQENVNVL	AKNAD1	201	Q5T1N1
DAHNVQAVIDSLALD	CEP95	61	Q96GE4
HSEATRAEAAAVVAQ	INSC	336	Q1MX18
DSIIHIGAIFEENAA	GRID1	21	Q9ULK0
DLVAIHTDGNEQISV	EML2	451	O95834
AVRVTAAHTAEAQAE	E4F1	6	Q66K89
VGAAVQHVDNLRAAL	HBM	66	Q6B0K9
DAVVQHSQLAAAVEN	EXOC3	101	O60645
VVGLQEHLVNSADDV	KIF2C	431	Q99661
NDVLAQLDAVVSFAH	MSH2	596	P43246
IHAITAANNLVAAAI	MTHFD1	446	P11586
AVGIIAASAFIQNHE	CNTD1	256	Q8N815
ATSHVGEIEQELALA	CLIP1	381	P30622
SADGDNVHLVLNVSE	IL17RC	286	Q8NAC3
AILDAVHGNIEDAVT	RGPD1	646	P0DJD0
HFAVADGNVTVVDVL	INVS	226	Q9Y283
AVLEAVAQAAHLPAD	RSAD1	111	Q9HA92
SHLIANADVQSIAVA	UTP4	231	Q969X6
LAQTVVDAGAVAHLA	SPAG6	201	O75602
ALQAAAHASVDIKNV	SMG5	991	Q9UPR3
ITFAILDAVHGNIED	RGPD2	651	P0DJD1
EAALHAAVIAINEAV	IQGAP2	211	Q13576
AAGAAADQVQLHSEL	SIX4	76	Q9UIU6
ENVLGAQLDVEAAHS	STX5	306	Q13190
SVEHQNIALEVDAFG	ABCA8	931	O94911
VQAVQAVHLESDAFL	BRCC3	6	P46736
EAIIGTDVLQDHNAI	ASPRV1	281	Q53RT3
AALNHRAGAEIAAVI	CMTM4	141	Q8IZR5
ASAHAANLVVVAISQ	CLRN2	196	A0PK11
QDQAAETIEALHAAG	ATP11C	656	Q8NB49
EGQDVVEAILAHLNT	TIMELESS	841	Q9UNS1
EQVAIVAQDLAAFHT	ZNF143	561	P52747
NTVLHALVEVADNTA	TRPV1	286	Q8NER1
VDLQNASHSEAVEAI	PATJ	1131	Q8NI35
DSIADHVNSAAVNVE	STX17	201	P56962
ALAVVIEVANHANDT	FGD6	1046	Q6ZV73
GASHNREILQVLADV	XYLB	441	O75191
IVDAANAVISHIDQT	TPP2	1076	P29144
VNAANVHEVLSAASL	ZBTB47	81	Q9UFB7
NVTANHRANDVIAAE	PITPNM3	631	Q9BZ71
VAAIAISEHVENAGV	CAD	1146	P27708
SAQVAVFHLQEIAED	ZNF512B	686	Q96KM6
VFASAEEALQAAAHV	ZNHIT2	256	Q9UHR6
QAHAVVAEEVAALTG	ZNHIT2	366	Q9UHR6
QAAADLNQSAGEVVH	TLN2	1246	Q9Y4G6
AALLIAAGADVNAHA	TRPV3	231	Q8NET8
VAASAIQGIQIAIHE	WNT10A	81	Q9GZT5
LAIQTHNFAAVAAAA	ZFP36L2	376	P47974
GNTVLHALVAIADNT	TRPV4	321	Q9HBA0
AVNITGLHNILDVAA	TDH	141	Q8IZJ6
VHLTAVSIDPADANV	ZDHHC1	96	Q8WTX9
VAAAAAAVHEQQIDE	ZFY	331	P08048
ALQLAVGNEHLEVTE	TRPC7	81	Q9HCX4
NEAIQAAHDAVAQEG	UCHL1	136	P09936
ELENAVSGHVVLEAT	MYO9B	1436	Q13459
DLEDQVATAAAQVHH	MYRIP	736	Q8NFW9
GEVIQAEVTVHAALE	PPP1R9B	316	Q96SB3
NESAHISDAVGVVAQ	GRIN1	276	Q05586
ISDAVGVVAQAVHEL	GRIN1	281	Q05586
TAVQDENGDSVLHLA	NFKB1	536	P19838
SAVAQGSQLVIHAVD	NECTIN2	306	Q92692