Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

PGA4 PGA5 CTSE PGA3

7.03e-0637674GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

PGA4 PGA5 CTSE PGA3

7.84e-0638674GO:0070001
GeneOntologyMolecularFunctionNAD(P)H dehydrogenase (quinone) activity

NQO1 NQO2

1.10e-045672GO:0003955
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

TNIK TGFBR1 NRG1 NEU1 TENM3 DDR2 DVL2 TENM1 SRF CUX1

4.75e-064946810GO:0031346
GeneOntologyBiologicalProcessneuron projection development

TNIK NRG1 NEU1 ARHGEF28 PLAA TENM3 DDR2 DVL2 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

1.48e-0512856815GO:0031175
GeneOntologyBiologicalProcessneuron development

TNIK NRG1 NEU1 ARHGEF28 PLAA TENM3 DDR2 DVL2 TENM1 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

1.63e-0514636816GO:0048666
GeneOntologyBiologicalProcessregulation of cell projection organization

TNIK TGFBR1 NRG1 NEU1 TENM3 DDR2 DVL2 TENM1 SRF TNR ULK2 CUX1

2.24e-058636812GO:0031344
GeneOntologyBiologicalProcessneuron projection morphogenesis

TNIK ARHGEF28 PLAA DVL2 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

5.80e-058026811GO:0048812
GeneOntologyBiologicalProcessneuron projection extension

PLAA SRF BCAN TNR ULK2 RNF157

6.20e-05207686GO:1990138
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TNIK ARHGEF28 PLAA DVL2 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

7.01e-058196811GO:0120039
GeneOntologyBiologicalProcessregulation of developmental growth

TGFBR1 NRG1 PLAA CAPN3 SRF TNR ULK2 RNF157

7.14e-05421688GO:0048638
GeneOntologyBiologicalProcesscell projection morphogenesis

TNIK ARHGEF28 PLAA DVL2 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

7.56e-058266811GO:0048858
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

TNIK TGFBR1 NRG1 NEU1 TENM3 DDR2 TENM1 SRF TNR ULK2 CUX1

9.35e-058466811GO:0120035
GeneOntologyBiologicalProcesscell morphogenesis

SOX6 TNIK NRG1 ARHGEF28 PLAA DVL2 SRF BCAN PAX2 TNR ULK2 CUX1 RNF157

1.22e-0411946813GO:0000902
GeneOntologyBiologicalProcessregulation of neuron projection development

TNIK NRG1 NEU1 TENM3 DDR2 SRF TNR ULK2 CUX1

1.74e-04612689GO:0010975
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix organization

TGFBR1 PHLDB1 DDR2

1.91e-0434683GO:1903055
GeneOntologyBiologicalProcesspositive regulation of filopodium assembly

TGFBR1 TENM1 SRF

2.26e-0436683GO:0051491
GeneOntologyBiologicalProcessheart trabecula morphogenesis

TGFBR1 NRG1 SRF

2.66e-0438683GO:0061384
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

1.14e-067683GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

5.33e-0611683GO:0031906
GeneOntologyCellularComponentendosome lumen

PGA4 PGA5 PGA3

3.70e-0443683GO:0031904
GeneOntologyCellularComponentGolgi lumen

MUC17 MUC19 MUC16 BCAN

4.41e-04109684GO:0005796
GeneOntologyCellularComponentperineuronal net

BCAN TNR

4.61e-0410682GO:0072534
GeneOntologyCellularComponentperisynaptic extracellular matrix

BCAN TNR

5.63e-0411682GO:0098966
GeneOntologyCellularComponentapical part of cell

TNIK TGFBR1 NRG1 MUC17 DDR2 DVL2 MFSD4B SLC29A2

6.54e-04592688GO:0045177
GeneOntologyCellularComponentsynapse-associated extracellular matrix

BCAN TNR

7.95e-0413682GO:0099535
GeneOntologyCellularComponentapical plasma membrane

TNIK TGFBR1 NRG1 MUC17 DDR2 MFSD4B SLC29A2

1.01e-03487687GO:0016324
DomainAspartic_peptidase_N

PGA4 PGA5 CTSE PGA3

5.25e-097674IPR012848
DomainA1_Propeptide

PGA4 PGA5 CTSE PGA3

5.25e-097674PF07966
DomainAspartic_peptidase_A1

PGA4 PGA5 CTSE PGA3

3.12e-0810674IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 CTSE PGA3

3.12e-0810674IPR033121
DomainAsp

PGA4 PGA5 CTSE PGA3

3.12e-0810674PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 CTSE PGA3

3.12e-0810674PS51767
Domain-

PGA4 PGA5 CTSE PGA3

7.33e-08126742.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 CTSE PGA3

7.33e-0812674PS00141
DomainAspartic_peptidase_AS

PGA4 PGA5 CTSE PGA3

1.06e-0713674IPR001969
DomainPeptidase_aspartic_dom

PGA4 PGA5 CTSE PGA3

3.47e-0717674IPR021109
DomainFlavodoxin_2

NQO1 NQO2

1.27e-052672PF02525
DomainFlavodoxin_fold

NQO1 NQO2

1.27e-052672IPR003680
DomainTox-GHH_dom

TENM3 TENM1

7.57e-054672IPR028916
DomainTen_N

TENM3 TENM1

7.57e-054672IPR009471
DomainTen_N

TENM3 TENM1

7.57e-054672PF06484
DomainTENEURIN_N

TENM3 TENM1

7.57e-054672PS51361
DomainTox-GHH

TENM3 TENM1

7.57e-054672PF15636
DomainYD

TENM3 TENM1

1.26e-045672IPR006530
DomainEGF_3

NRG1 TENM3 MUC17 TENM1 BCAN TNR

1.96e-04235676PS50026
DomainEGF

NRG1 TENM3 MUC17 TENM1 BCAN TNR

1.96e-04235676SM00181
DomainEGF-like_dom

NRG1 TENM3 MUC17 TENM1 BCAN TNR

2.67e-04249676IPR000742
DomainEGF_1

NRG1 TENM3 MUC17 TENM1 BCAN TNR

3.04e-04255676PS00022
DomainEGF-like_CS

NRG1 TENM3 MUC17 TENM1 BCAN TNR

3.44e-04261676IPR013032
DomainEGF_2

NRG1 TENM3 MUC17 TENM1 BCAN TNR

3.73e-04265676PS01186
DomainFlavoprotein-like_dom

NQO1 NQO2

5.60e-0410672IPR029039
Domain-

NQO1 NQO2

5.60e-04106723.40.50.360
DomainNHL

TENM3 TENM1

9.64e-0413672PS51125
DomainSEA

MUC17 MUC16

1.12e-0314672SM00200
Domain-

MUC17 MUC16

1.29e-03156723.30.70.960
DomainEGF_extracell

TENM3 TENM1 TNR

1.30e-0360673IPR013111
DomainEGF_2

TENM3 TENM1 TNR

1.30e-0360673PF07974
DomainPDZ

IL16 PCLO DVL2 MPP7

2.12e-03151674PS50106
DomainPDZ

IL16 PCLO DVL2 MPP7

2.17e-03152674IPR001478
DomainSEA

MUC17 MUC16

2.80e-0322672PF01390
DomainSEA

MUC17 MUC16

3.06e-0323672PS50024
DomainSEA_dom

MUC17 MUC16

3.06e-0323672IPR000082
DomaintRNA-bd_arm

SOX6 CUX1

3.33e-0324672IPR010978
DomainK_chnl_volt-dep_Kv

KCND1 KCNS2

4.20e-0327672IPR003968
DomainFHA

PHLDB1 STARD9

5.51e-0331672PF00498
DomainVG_K_chnl

KCND1 KCNS2

6.23e-0333672IPR028325
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGA3

8.58e-0611543M39726
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC19 MUC16

6.73e-0521543MM15706
PathwayREACTOME_SURFACTANT_METABOLISM

PGA4 PGA5 PGA3

2.00e-0430543M27566
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

NEU1 MUC17 MUC16 BCAN RFT1

2.12e-04143545M27275
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

7.47e-0936933017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

7.47e-09369321989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

7.47e-0936939855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

7.47e-0936939797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

7.47e-0936932478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

7.47e-0936933815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

7.47e-09369310675278
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

7.47e-0936937926498
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

7.47e-0936933780036
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

7.47e-0936939561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

7.47e-09369321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

7.47e-09369319800305
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

7.47e-0936932901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

7.47e-0936933839486
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

7.47e-09369324170207
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

7.47e-0936933467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

7.47e-0936934586732
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

7.47e-0936933014868
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

7.47e-0936932892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

7.47e-09369324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

7.47e-0936931455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

7.47e-0936932831884
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

7.47e-0936932799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

7.47e-09369319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

7.47e-0936931968039
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

7.47e-0936932032552
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

7.47e-0936938053437
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

7.47e-0936931812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

7.47e-0936937923573
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

7.47e-0936932566575
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

7.47e-0936939061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

7.47e-09369312588289
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

7.47e-0936932229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

7.47e-09369325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

7.47e-09369319890696
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

7.47e-09369323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

7.47e-09369311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

7.47e-0936931956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

7.47e-0936938540382
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

7.47e-0936938244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

7.47e-09369321407214
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

7.47e-09369322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

7.47e-09369320981206
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

7.47e-0936936774973
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

7.47e-0936938504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

7.47e-09369321970995
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

7.47e-0936936300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

7.47e-09369322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

7.47e-09369324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

7.47e-0936938038355
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

7.47e-09369320428942
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

7.47e-0936932227273
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

7.47e-0936939525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

7.47e-0936937886402
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

7.47e-09369323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

7.47e-09369324125879
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

7.47e-09369317379991
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

7.47e-0936938751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

7.47e-0936933554488
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

7.47e-09369321547904
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

7.47e-09369323521833
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

2.99e-08469323047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

2.99e-08469311915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

2.99e-0846938322031
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

2.99e-08469317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

2.99e-08469312698190
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

7.45e-08569322066020
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK ZNF536 PHLDB1 TENM3 STARD9 ULK2 ADCY3 RNF157 PRRC2B

1.15e-0740769912693553
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

NRG1 TENM3 PAX2

2.60e-07769310625539
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TNIK PCLO ADCY3 MED13 PRRC2B

2.20e-061056959628581
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

ZNF536 POM121C ZNF281 CUX1 PRRC2B

3.59e-0611669530804394
Pubmed

Null association of NQO1 609C>T and NQO2 -3423G>A polymorphisms with susceptibility and prognosis of Esophageal cancer in north Indian population and meta-analysis.

NQO1 NQO2

3.88e-06269222770696
Pubmed

Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy.

NQO1 NQO2

3.88e-06269210945627
Pubmed

BALT development and augmentation of hyperoxic lung injury in mice deficient in NQO1 and NQO2.

NQO1 NQO2

3.88e-06269216678022
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

3.88e-0626927663352
Pubmed

Analysis of WDFY4 rs7097397 and PHLDB1 rs7389 polymorphisms in Chinese patients with systemic lupus erythematosus.

PHLDB1 WDFY4

3.88e-06269235188604
Pubmed

Cancer-associated variants of human NQO1: impacts on inhibitor binding and cooperativity.

NQO1 NQO2

3.88e-06269231431515
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

3.88e-0626922714789
Pubmed

Mouse NRH:quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression.

NQO1 NQO2

3.88e-06269210903442
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

3.88e-0626923197840
Pubmed

In vivo role of NAD(P)H:quinone oxidoreductase 1 in metabolic activation of mitomycin C and bone marrow cytotoxicity.

NQO1 NQO2

3.88e-06269217804703
Pubmed

NQO1 and NQO2 regulation of humoral immunity and autoimmunity.

NQO1 NQO2

3.88e-06269216905546
Pubmed

NAD(P)H:quinone oxidoreductase 1 and nrh:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism.

NQO1 NQO2

3.88e-06269217332305
Pubmed

Two minor NQO1 and NQO2 alleles predict poor response of breast cancer patients to adjuvant doxorubicin and cyclophosphamide therapy.

NQO1 NQO2

3.88e-06269221946896
Pubmed

Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity.

NQO1 NQO2

3.88e-06269215935811
Pubmed

Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.

PGA4 PGA5

3.88e-0626922415509
Pubmed

Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.

NQO1 NQO2

3.88e-0626922843525
Pubmed

Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Characterization of the mechanism of inhibition in both cell-free and cellular systems.

NQO1 NQO2

3.88e-06269221718050
Pubmed

Genetic differences in induction of cytosol reduced-NAD(P):menadione oxidoreductase and microsomal aryl hydrocarbon hydroxylase in the mouse.

NQO1 NQO2

3.88e-062692833115
Pubmed

No associations between Parkinson's disease and polymorphisms of the quinone oxidoreductase (NQO1, NQO2) genes.

NQO1 NQO2

3.88e-06269215694256
Pubmed

Role of NQO1 609C>T and NQO2-3423G>A polymorphisms in susceptibility to gastric cancer in Kashmir valley.

NQO1 NQO2

3.88e-06269221294640
Pubmed

Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.

NQO1 NQO2

3.88e-06269212351651
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC17 MUC19 MUC16

5.97e-061869318834073
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

PGA4 PGA5 PGA3

5.97e-061869336057966
Pubmed

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells.

NRG1 SRF

1.16e-05369226885614
Pubmed

Association analyses between polymorphisms of the phase II detoxification enzymes (GSTM1, NQO1, NQO2) and alcohol withdrawal symptoms.

NQO1 NQO2

1.16e-05369212960511
Pubmed

Genomic structure and chromosomal localization of the mouse LIM domain-binding protein 1 gene, Ldb1.

COL17A1 PAX2

1.16e-0536929503020
Pubmed

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS.

BCAN TNR

1.16e-05369219141078
Pubmed

Cumulus cells of euploid versus whole chromosome 21 aneuploid embryos reveal differentially expressed genes.

DVL2 SRF

1.16e-05369234417138
Pubmed

An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2.

NQO1 NQO2

1.16e-05369211688992
Cytoband1q31

BCAN CTSE

3.74e-04196921q31
GeneFamilyCD molecules|Mucins

MUC17 MUC19 MUC16

1.51e-0521423648
GeneFamilyPDZ domain containing

IL16 PCLO DVL2 MPP7

4.19e-041524241220
CoexpressionGSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP

SOX6 KAT6A TENM1 AHDC1 CUX1 KRT73

1.07e-05189696M4199
CoexpressionGSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN

KIF23 EHMT1 CTSE WDFY4 CUX1 RNF157

1.47e-05200696M304
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 NRG1 ZNF536 ARHGEF28 TENM3 PAX2

2.45e-07168696a086c306be430adf0632ba53e98cd8014d2de330
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 NRG1 ZNF536 ARHGEF28 TENM3 PAX2

3.44e-07178696544379f5a6145429762258d426b876bb36c112f5
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EBF2 SOX6 PHLDB1 STARD9 DDR2 ADCY3

3.79e-07181696451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 TNIK TGFBR1 TENM3 PAX2 TOP6BL

5.19e-071916963e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 TNIK TGFBR1 TENM3 PAX2 TOP6BL

5.69e-0719469604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 TNIK TGFBR1 TENM3 PAX2 TOP6BL

5.69e-0719469669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ARHGEF28 TOP6BL MPP7 FOXI1

5.63e-06164695d847d509bb1791638032ade6755d8164586b5bd5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ARHGEF28 TOP6BL MPP7 FOXI1

5.98e-061666956fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ARHGEF28 TOP6BL MPP7 FOXI1

6.52e-061696954b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ARHGEF28 TOP6BL MPP7 FOXI1

6.52e-06169695a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRG1 ZNF536 PHLDB1 DDR2 MAML2

7.51e-06174695f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGEF28 PAX2 TOP6BL MPP7 FOXI1

7.94e-0617669545028197364c64e93e3ffe86aff773d47a477d49
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ARHGEF28 PCLO TENM1 PAX2

8.85e-06180695358923e4228035a3e90e2957392089219e90dcd7
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 PHLDB1 BCAN MAML2 TNR

9.34e-061826958a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 PHLDB1 BCAN MAML2 TNR

9.34e-06182695e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

EBF2 IL16 PHLDB1 DDR2 MN1

9.85e-061846952b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF536 TENM3 TENM1 ITGA9

1.04e-0518669596f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 IL16 DDR2 TOP6BL MAML2

1.06e-051876954ea486991f66c29728d127171a07b81404ec0b78
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 NRG1 ARHGEF28 PCLO PAX2

1.06e-05187695d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EBF2 PHLDB1 STARD9 DDR2 ADCY3

1.15e-051906954eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EBF2 PHLDB1 STARD9 DDR2 ADCY3

1.15e-051906957be4341e2909101d756f14031c21e705eb45e69a
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 PHLDB1 STARD9 DDR2 MAML2

1.18e-0519169570c067c54084bfb02c29bab085f4defd477194fb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 ARHGEF28 PCLO PAX2 CUX1

1.24e-0519369582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 ARHGEF28 PCLO PAX2 CUX1

1.24e-051936953866667dd221612589ae50f5c52f73a183a49ce6
ToppCellLA|World / Chamber and Cluster_Paper

EBF2 IL16 DDR2 TOP6BL MAML2

1.24e-05193695d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

EBF2 PHLDB1 DDR2 TOP6BL MAML2

1.27e-05194695d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

EBF2 PHLDB1 DDR2 TOP6BL MAML2

1.30e-05195695a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF536 TENM3 STARD9 TENM1 BCAN

1.37e-05197695e239caae24f40564a24ad909754f5436f767ccdb
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF536 TENM3 TENM1 ITGA9

1.47e-05200695a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 PHLDB1 DDR2 MN1 ADCY3

1.47e-05200695ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF536 TENM3 TENM1 ITGA9

1.47e-0520069533b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL3 ARHGEF28 PCLO MUC16 MPP7

1.47e-05200695d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 IL16 TENM3 DDR2 RNF157

1.47e-05200695b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF536 TENM3 TENM1 ITGA9

1.47e-052006959719fabddc34051949468a7520289e3c750de4f8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 IL16 STARD9 DDR2 TENM1

1.47e-052006950c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 IL16 TENM3 DDR2 RNF157

1.47e-052006957c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF536 DDR2 TENM1 ITGA9

3.30e-051176940602bbad908cb28c5093b74d717da5f2af577943
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

ACSL3 KIF23 MUC19 PAX2

4.97e-05130694169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF536 ARHGEF28 DDR2 ITGA9

1.09e-041596940dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.11e-041606941e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX6 ZNF536 WDFY4 RNF157

1.14e-0416169476c993a4533362db2250c88b3ee3ede55362d54e
ToppCellRSV-Healthy-6|Healthy / Virus stimulation, Condition and Cluster

TGFBR1 SRF AGBL2 POM121C

1.22e-041646941b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 ERICH3 MUC16 AGBL2

1.22e-041646940e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX6 ZNF536 WDFY4 RNF157

1.22e-041646945638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellRSV-Healthy-6|RSV / Virus stimulation, Condition and Cluster

TGFBR1 SRF AGBL2 POM121C

1.22e-04164694ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STARD9 TOP6BL WDFY4 ADCY3

1.25e-0416569476abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 TENM3 ITGA9 TNR

1.28e-0416669443f84d3cd58e93ce00c241656c4cba27604b4932
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.37e-041696942a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL16 KCND1 TNR MPP7

1.40e-0417069428fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL16 KCND1 TNR MPP7

1.40e-04170694239cb4b801b2d71a6facb386f2684c0851504151
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.50e-041736940bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|356C / Donor, Lineage, Cell class and subclass (all cells)

PDCD1 TOP6BL MFSD4B RNF157

1.50e-04173694e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DNAAF3 ERICH3 ARHGEF28 AGBL2

1.54e-04174694f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.57e-0417569477c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DNAAF3 ERICH3 ARHGEF28 AGBL2

1.57e-04175694c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.57e-0417569498947a226b5a2ac7091ff9d34243ea7736add973
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 PCLO NQO1 MPP7

1.57e-04175694f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DDR2 MAML2 MN1

1.57e-041756940c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF536 TENM3 TENM1

1.60e-04176694322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.60e-04176694cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TOP6BL MPP7 FOXI1

1.60e-04176694c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellHealthy-RBC|World / disease group, cell group and cell class

SOX6 KIF23 PGA5 CTSE

1.64e-041776942ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 IL16 CAPN3 RNF157

1.64e-041776947853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAAF3 KCND1 ITGA9 MPP7

1.64e-04177694227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ZNF536 IL16 DDR2

1.64e-041776949ec7f1e64312d26d434b3312b58386715dbad644
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAAF3 KCND1 ITGA9 MPP7

1.64e-0417769466ffa279147961080c104242a08b176e301d80e3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ZNF536 IL16 DDR2

1.64e-04177694016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellHealthy-RBC|Healthy / disease group, cell group and cell class

SOX6 KIF23 PGA5 CTSE

1.64e-04177694945d72ab52efa9a9468daace9f9ec676a891d963
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 IL16 CAPN3 RNF157

1.64e-04177694395f005f019aabb18738d3a10a04c37f216deda3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAAF3 KCND1 ITGA9 MPP7

1.64e-041776940cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 IL16 CAPN3 RNF157

1.64e-041776949a5bf67a801826d094f679dd2189b62296c9694f
ToppCell3'_v3-Lung-Myeloid_Mac-Erythrophagocytic_macrophages|Lung / Manually curated celltypes from each tissue

MUC17 ITGA9 CTSE MN1

1.68e-04178694b63cee443cc1b7416112bf610d7c9d41e4fa37ed
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 PDCD1 ZNF536 TENM1

1.68e-04178694c982a73955c9c193bcab21d60d453afcc09cd586
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DDR2 MAML2 MN1

1.68e-04178694e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF536 IL16 KIF23 FEM1C

1.68e-04178694c87945146b2734141f07b39d268e0d8086ee0364
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF536 TENM3 TENM1

1.71e-04179694d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

SOX6 TNIK PHLDB1 PCLO

1.71e-041796941526a130565a97c291a25a7a988089bffc1515c1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 TGFBR1 MUC19 TOP6BL

1.71e-04179694d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DDR2 MAML2 MN1

1.75e-04180694392bc71a69653ba12de31bed4e9357f181094641
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 ARHGEF28 TENM3 MUC19

1.79e-041816949de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZNF536 PHLDB1 DDR2 ITGA9

1.79e-04181694d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DDR2 MAML2 MN1

1.79e-041816948fd64404e57c22c204d835fc5626f73554257b19
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 NRG1 PAX2 MAML2

1.79e-041816946956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ARHGEF28 PCLO TENM1

1.79e-041816946980ea624151da32b7f537f263e40fcb87a02e81
ToppCellfacs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 SRF ADCY3 CUX1

1.82e-0418269422d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 BCAN MAML2 TNR

1.82e-04182694a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 BCAN MAML2 TNR

1.82e-04182694831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ACSL3 NRG1 ZNF536 PHLDB1

1.82e-04182694ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 BCAN MAML2 TNR

1.82e-041826943cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 BCAN MAML2 TNR

1.82e-041826945d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 ARHGEF28 TENM1 PAX2

1.86e-041836946878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

ARHGEF28 COL17A1 MUC17 MUC16

1.86e-0418369415d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF536 TENM3 TENM1

1.86e-0418369404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

EBF2 TOP6BL MPP7 FOXI1

1.86e-041836945c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK TENM1 MAML2 RNF157

1.86e-04183694f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF536 TENM3 TENM1

1.90e-041846941158a55c1990fd23d270cb6510d0951c4bfcddc5
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 PHLDB1 CAPN3 MAML2

1.90e-04184694a2191dd5546efd357b23e625beb3c5820476f243
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

ARHGEF28 COL17A1 MUC17 MUC16

1.90e-04184694d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 BCAN MAML2 TNR

1.94e-04185694efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 SOX6 PHLDB1 DDR2

1.94e-041856948f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
Diseaseoveractive bladder syndrome (biomarker_via_orthology)

NRG1 NQO1

3.04e-054672DOID:0070355 (biomarker_via_orthology)
Diseaseneurotic disorder

SOX6 TENM3 PCLO AGBL2

8.40e-05101674EFO_0004257
Diseaseresponse to platinum based chemotherapy, response to antineoplastic agent

ZNF536 FOXI1

1.06e-047672EFO_0004647, GO_0097327
Diseasethiamine measurement

NRG1 MAML2

2.26e-0410672EFO_0010540
Diseasefructose measurement

TNIK NRG1

3.90e-0413672EFO_0010477
Diseaseunipolar depression, bipolar disorder

SOX6 ZNF536 STARD9 PCLO

4.45e-04156674EFO_0003761, MONDO_0004985
Diseaseuric acid measurement

TNIK NRG1 DNAJC13 TOP6BL RFT1 SLC29A2 PRRC2B

4.64e-04610677EFO_0004761
Diseasehearing loss

PHLDB1 ARHGEF28 DVL2

4.83e-0467673EFO_0004238
DiseaseContact Dermatitis

NRG1 NQO1 NQO2

5.73e-0471673C0011616
DiseaseContact hypersensitivity

NRG1 NQO1 NQO2

5.73e-0471673C0162351
DiseaseMalignant neoplasm of breast

NRG1 NQO1 TENM1 EHMT1 ITGA9 FEM1C NQO2 ZNF281 CUX1

6.96e-041074679C0006142
Diseaseresponse to antidepressant

MUC19 ITGA9 FEM1C CUX1

7.00e-04176674GO_0036276
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

MAML2 CUX1

1.04e-0321672EFO_0004616, EFO_0010726, EFO_1000786
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC16

1.36e-0324672DOID:12894 (is_marker_for)
DiseaseEarly Pregnancy Loss

TGFBR1 IL16 TNR

1.98e-03109673C3830362
DiseaseMiscarriage

TGFBR1 IL16 TNR

1.98e-03109673C4552766
DiseaseSpontaneous abortion

TGFBR1 IL16 TNR

1.98e-03109673C0000786
DiseaseAbortion, Tubal

TGFBR1 IL16 TNR

1.98e-03109673C0000822
Diseasecentral nervous system cancer, glioma

PHLDB1 MAML2

1.98e-0329672EFO_0000326, EFO_0005543
Diseasestroke outcome severity measurement

DNAAF3 PLAA TNR

2.25e-03114673EFO_0009603

Protein segments in the cluster

PeptideGeneStartEntry
IPSGPSEGGSSSTMY

COL17A1

976

Q9UMD9
SEGGSSSTMYVSGPP

COL17A1

981

Q9UMD9
MTVTYTTEAGVGTPG

ERICH3

1421

Q5RHP9
GSTSMIFSTGPYSTN

CUX1

501

P39880
SPYGIMSSSPTVGSS

EBF2

506

Q9HAK2
GGYMVPKGTTASATS

AHDC1

1066

Q5TGY3
PAYPGSSSMSTITSG

DVL2

391

O14641
DIYGGTMLSSGSGPV

RFT1

356

Q96AA3
ITGMPASTEGAYVSS

NRG1

136

Q02297
ETVSITYGTGSMTGI

PGA5

131

P0DJD9
SEGYSPVTMGSGSVT

ARHGEF28

76

Q8N1W1
YSIPIMEDGGGGSST

BCAN

406

Q96GW7
DGYGMTPLLSASVTG

FEM1C

211

Q96JP0
TSSMGITYPTGDTNV

MUC16

9251

Q8WXI7
TTLGYGDMVPSTIAG

KCND1

371

Q9NSA2
SVSGGYSMLPGGCVT

KRT73

486

Q86Y46
GVTGGNTYSVPAVTM

DDR2

531

Q16832
SVYMSSNPEGGAGSE

CTSE

216

P14091
TTGEVMDYSSKTTGP

PCLO

3031

Q9Y6V0
EGYTTKGSQTMTSSG

PCLO

3701

Q9Y6V0
TEYATIVFPSGMGTS

PDCD1

246

Q15116
VSPTVTGASGMAGTT

MUC19

1721

Q7Z5P9
TGYTETSGPSAGVTV

MUC19

3151

Q7Z5P9
SSDSSYMSGSPGGSP

IL16

511

Q14005
SMTTVGYGDVVPGTT

KCNS2

371

Q9ULS6
MPALSTGSGSDTGLY

MPP7

1

Q5T2T1
SVTTGGTAEMYTKTG

NQO2

146

P16083
TSVYGASMATTFPSG

MFSD4B

326

Q5TF39
SITTGGSGSMYSLQG

NQO1

146

P15559
GSYPTSTLAGMVPGS

PAX2

351

Q02962
ETVSITYGTGSMTGI

PGA3

131

P0DJD8
MSSLTGAYTSGIPSS

POM121C

371

A8CG34
MQPTAQYSGGSSTIS

MAML2

811

Q8IZL2
TSITGIMSPTSFVYG

ITGA9

771

Q13797
PSSYDSTMGGSICGN

KAT6A

1566

Q92794
MTTPAGSGSGFGSVS

DNAAF3

1

Q8N9W5
SYTMESTFGGSTLGN

AGBL2

626

Q5U5Z8
YTGPSNATAGMETEG

ADCY3

731

O60266
TIGSTYMAASGVTPD

ADCY3

976

O60266
GVAGYLTAGTSTSVM

DNAJC13

2211

O75165
MTSGANSSGSYLPSE

CCDC196

1

A0A1B0GTZ2
FLSSMTAYVSGGSPT

FOXI1

281

Q12951
IDDGTNMTYGTSPSG

CAPN3

266

P20807
GSAEQTAPGDSTGYM

EHMT1

466

Q9H9B1
ETVSITYGTGSMTGI

PGA4

131

P0DJD7
YGVTGSGKTHTMTGS

KIF23

111

Q02241
GIMSNSTSTPDSYGG

MN1

1106

Q10571
EGTSMPTSTYSEGRT

MUC17

851

Q685J3
ADGTSMPTSTYSEGS

MUC17

1086

Q685J3
PAEGTSMPTSTYSEG

MUC17

1321

Q685J3
EGTSMPTSTYTEGRT

MUC17

1676

Q685J3
DGTSMPTPAYSEGST

MUC17

1971

Q685J3
GTSMPTSTYSEGSTP

MUC17

2561

Q685J3
EGTSMPISTYSEGST

MUC17

3091

Q685J3
TVSSMSGSYIAPGTE

RNF157

531

Q96PX1
GSLFGQLGTMPSTYS

SLC29A2

146

Q14542
SEEGSYSQDMTGVTP

TOP6BL

91

Q8N6T0
GPSGYSSLATLEGSM

NEU1

366

Q99519
RGTESMDTTYSPIGG

TENM1

366

Q9UKZ4
TTVGSRRPGGMTSTY

SUPT5H

751

O00267
GSGKTYTMLGTPASV

STARD9

106

Q9P2P6
SGMTSGYNSSPALSG

STARD9

4406

Q9P2P6
EYGSMDTTPGGTVLE

MED13

856

Q9UHV7
MYAPTSGLGDGSLTV

SRF

416

P11831
IYDMTTSGSGSGLPL

TGFBR1

181

P36897
TTGTGVVYPGAITMA

SOX6

736

P35712
YTSGSTGLPKGVMIS

ACSL3

286

O95573
TYDTAGLTMPTATLG

CIZ1

106

Q9ULV3
TEYGMGSSTKASFTP

TNIK

961

Q9UKE5
SSSTTGLPDMTGSVY

UBAP2

1006

Q5T6F2
GAGRYVPGSASMGTT

PLAA

496

Q9Y263
MYATNGPLTSGTIST

TNR

1021

Q92752
STVMGTSTEYSVSGG

WDFY4

1041

Q6ZS81
SYSVEMPTVSSSGGI

ZNF281

436

Q9Y2X9
SSGVNYSSFGGVSMP

PRRC2B

1891

Q5JSZ5
TATPGYTMASGSVYS

TENM3

266

Q9P273
PTSPGAMSVGSSYEN

PHLDB1

236

Q86UU1
MSAAPLVGYSSSGSE

USB1

1

Q9BQ65
GVYPGMVGSGASSSC

ZNF536

1116

O15090
MYSGSVSGSSCGSSP

ULK2

286

Q8IYT8