Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Anaphylatoxin_comp_syst	C4A C4B	1.89e-04	5	82	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	1.89e-04	5	82	2	IPR001840
Domain	TIMP-like_OB-fold	METRN C4A C4B	1.97e-04	26	82	3	IPR008993
Domain	ANATO	C4A C4B	3.94e-04	7	82	2	SM00104
Domain	ANATO	C4A C4B	3.94e-04	7	82	2	PF01821
Domain	ANAPHYLATOXIN_2	C4A C4B	3.94e-04	7	82	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	3.94e-04	7	82	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	3.94e-04	7	82	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	5.24e-04	8	82	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	5.24e-04	8	82	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	5.24e-04	8	82	2	IPR019742
Domain	A2M_N	C4A C4B	8.38e-04	10	82	2	PF01835
Domain	A2M_N	C4A C4B	8.38e-04	10	82	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	8.38e-04	10	82	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	8.38e-04	10	82	2	PS00477
Domain	A2M	C4A C4B	8.38e-04	10	82	2	PF00207
Domain	A2M_N_2	C4A C4B	8.38e-04	10	82	2	IPR011625
Domain	A2M_comp	C4A C4B	8.38e-04	10	82	2	IPR011626
Domain	A2M_N_2	C4A C4B	8.38e-04	10	82	2	PF07703
Domain	A2M_recep	C4A C4B	8.38e-04	10	82	2	PF07677
Domain	A2M_comp	C4A C4B	8.38e-04	10	82	2	PF07678
Domain	Macroglobln_a2	C4A C4B	8.38e-04	10	82	2	IPR001599
Domain	C345C	C4A C4B	2.48e-03	17	82	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	2.78e-03	18	82	2	IPR008930
Domain	NTR	C4A C4B	3.10e-03	19	82	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	3.10e-03	19	82	2	IPR018933
Domain	NTR	C4A C4B	4.54e-03	23	82	2	PS50189
Domain	Netrin_domain	C4A C4B	4.54e-03	23	82	2	IPR001134
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 KMT2C LRFN1 NAPRT MYOM3 PCNX1 PFAS RIPOR1 AKT2 LMNB2 PLXND1 SH2B2 SMURF2	2.43e-06	1105	84	13	35748872
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	5.76e-06	2	84	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	5.76e-06	2	84	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	5.76e-06	2	84	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	5.76e-06	2	84	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	5.76e-06	2	84	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	5.76e-06	2	84	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	5.76e-06	2	84	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	5.76e-06	2	84	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	5.76e-06	2	84	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	5.76e-06	2	84	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	5.76e-06	2	84	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	5.76e-06	2	84	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	5.76e-06	2	84	2	12207352
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	5.76e-06	2	84	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	5.76e-06	2	84	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	5.76e-06	2	84	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	5.76e-06	2	84	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	5.76e-06	2	84	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	5.76e-06	2	84	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	5.76e-06	2	84	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	5.76e-06	2	84	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	5.76e-06	2	84	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	5.76e-06	2	84	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	5.76e-06	2	84	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	5.76e-06	2	84	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	5.76e-06	2	84	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	5.76e-06	2	84	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	5.76e-06	2	84	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	5.76e-06	2	84	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	5.76e-06	2	84	2	2997024
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	5.76e-06	2	84	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	5.76e-06	2	84	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	5.76e-06	2	84	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	5.76e-06	2	84	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	5.76e-06	2	84	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	5.76e-06	2	84	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	5.76e-06	2	84	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	5.76e-06	2	84	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	5.76e-06	2	84	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	5.76e-06	2	84	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	5.76e-06	2	84	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	5.76e-06	2	84	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	5.76e-06	2	84	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	5.76e-06	2	84	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	5.76e-06	2	84	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	5.76e-06	2	84	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	5.76e-06	2	84	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	5.76e-06	2	84	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	5.76e-06	2	84	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	5.76e-06	2	84	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	5.76e-06	2	84	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	5.76e-06	2	84	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	5.76e-06	2	84	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	5.76e-06	2	84	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	5.76e-06	2	84	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	5.76e-06	2	84	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	5.76e-06	2	84	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	5.76e-06	2	84	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	5.76e-06	2	84	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	5.76e-06	2	84	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	5.76e-06	2	84	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	5.76e-06	2	84	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	5.76e-06	2	84	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	5.76e-06	2	84	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	5.76e-06	2	84	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	5.76e-06	2	84	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	5.76e-06	2	84	2	7365238
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	5.76e-06	2	84	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	5.76e-06	2	84	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	5.76e-06	2	84	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	5.76e-06	2	84	2	17971360
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	5.76e-06	2	84	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	5.76e-06	2	84	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	5.76e-06	2	84	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	5.76e-06	2	84	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	5.76e-06	2	84	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	5.76e-06	2	84	2	6881182
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	5.76e-06	2	84	2	3944109
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	5.76e-06	2	84	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	5.76e-06	2	84	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	5.76e-06	2	84	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	5.76e-06	2	84	2	35898513
Pubmed	Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.	C4A C4B	5.76e-06	2	84	2	33353966
Pubmed	Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp).	C4A C4B	5.76e-06	2	84	2	3008092
Pubmed	Wnt5a promotes vasculogenic mimicry and epithelial-mesenchymal transition via protein kinase Cα in epithelial ovarian cancer.	WNT5A PRKCA	5.76e-06	2	84	2	24898696
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	5.76e-06	2	84	2	28873507
Pubmed	The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.	C4A C4B	5.76e-06	2	84	2	6609966
Pubmed	Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.	C4A C4B	5.76e-06	2	84	2	2900855
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	5.76e-06	2	84	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	5.76e-06	2	84	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	5.76e-06	2	84	2	3794341
Pubmed	Complement and c4 null alleles in severe chronic adult periodontitis.	C4A C4B	5.76e-06	2	84	2	17257223
Pubmed	Three extra copies of a C4-related gene in H-2w7 mice are C4/Slp hybrid genes generated by multiple recombinational events.	C4A C4B	5.76e-06	2	84	2	2272665
Pubmed	Multiple C4/Slp genes distinguished by expression after transfection.	C4A C4B	5.76e-06	2	84	2	3023818
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	5.76e-06	2	84	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	5.76e-06	2	84	2	32691186
Pubmed	Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.	C4A C4B	5.76e-06	2	84	2	23259761
Pubmed	Lack of evidence of a specific role for C4A gene deficiency in determining disease susceptibility among C4-deficient patients with systemic lupus erythematosus (SLE).	C4A C4B	5.76e-06	2	84	2	11168010
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	5.76e-06	2	84	2	8390682
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.88e-04	9	52	2	1234
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	4.80e-03	36	52	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	5.07e-03	37	52	2	454
Coexpression	DOUGLAS_BMI1_TARGETS_UP	POGLUT3 WNT5A DCHS1 TCIRG1 CERCAM IGSF9 LMNB2 MAP3K21 DUS3L NCOA5	1.28e-05	563	84	10	M15103
Coexpression	BILD_E2F3_ONCOGENIC_SIGNATURE	SFMBT1 ABHD15 WNT5A SSX2IP ANKRD18A PLXND1 MAP3K21	1.52e-05	248	84	7	M13061
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-\|bone_marrow / Manually curated celltypes from each tissue	CAPN12 ABHD15 IFRD1 DUSP2 ARPC5L PLXND1	1.57e-06	189	84	6	6e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
Disease	Agouti-related protein measurement	RIPOR1 CBFB CDH15	5.36e-05	27	80	3	EFO_0008016
Disease	X-linked infantile spasms	PIGQ SCN1A	2.01e-04	8	80	2	C4552072
Disease	prostate carcinoma (is_implicated_in)	PRKCA AKT2	5.55e-04	13	80	2	DOID:10286 (is_implicated_in)
Disease	Early infantile epileptic encephalopathy with suppression bursts	PIGQ SCN1A	8.50e-04	16	80	2	C0393706
Disease	Usual Interstitial Pneumonia	RTEL1 WNT5A	1.20e-03	19	80	2	C4721509
Disease	Hamman-Rich Disease	RTEL1 WNT5A	1.20e-03	19	80	2	C4721508
Disease	Familial Idiopathic Pulmonary Fibrosis	RTEL1 WNT5A	1.34e-03	20	80	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	RTEL1 WNT5A	1.47e-03	21	80	2	C1800706
Disease	glioma	RTEL1 CYP4F12	1.62e-03	22	80	2	EFO_0005543
Disease	Neurodevelopmental Disorders	KMT2C SCN1A GIGYF2	2.09e-03	93	80	3	C1535926
Disease	uterine fibroid	POGLUT3 RTEL1 KCTD8 PGBD2	2.13e-03	199	80	4	EFO_0000731
Disease	Cholangiocarcinoma	KMT2C PTPN3	2.26e-03	26	80	2	C0206698
Disease	immune system disease	B4GALNT1 ELMO1	2.62e-03	28	80	2	EFO_0000540

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSRERVFTEERARFY	AKT2	241	P31751
RRREDFRRCLFLSFV	LINC00242	26	Q5T6M2
RDIIFELRRIAFDAE	ELMO1	321	Q92556
DAAEVERCLTRRFRD	ANKRD18A	46	Q8IVF6
VLREDSRAAFRLFET	C4B	1631	P0C0L5
DDDFVFTARTRLERL	B4GALNT1	356	Q00973
FERERRSFTEAAIRL	SSX2IP	446	Q9Y2D8
ERAVRETFRKARAVA	SPATA5	706	Q8NB90
FREERARDVAARYSQ	ANKRD45	141	Q5TZF3
REVRFERAEQALRRF	DUS3L	221	Q96G46
SRLFRSRSLREFEEA	ABHD15	306	Q6UXT9
SFRALTEFFRTEERI	ABHD15	411	Q6UXT9
ALVIRRRAVRSFADF	PTPN3	591	P26045
LTSRQFREDDFRRVV	SHMT2	431	P34897
LSSRFRRVDIDEFDE	ARPC5L	6	Q9BPX5
VLDREQRDRYRFTAV	DCHS1	106	Q96JQ0
RDSRARFFIDRDGFL	KCTD8	91	Q6ZWB6
FSESFQERERKERLR	KMT2C	3391	Q8NEZ4
DFASFRVDRIERVAR	HRG	171	P04196
RRVAAFRFELREDGR	METRN	141	Q9UJH8
FRKSVFEEEVRETRR	LMNB2	221	Q03252
RLTDNFIAAVRRRDF	LRFN1	71	Q9P244
RRVRLDEAFDFVKQR	DUSP2	276	Q05923
DFREEVSRRLRYESQ	CALHM2	171	Q9HA72
LRDFEERRRLFVEGC	EID2B	111	Q96D98
EEAVSFRRERSTFRR	PCNX1	776	Q96RV3
FRFADVRAAIRAART	PLXND1	391	Q9Y4D7
ASRVFDREEQERFIF	PCDH9	526	Q9HC56
QAFEEARRRTREFED	CBFB	141	Q13951
DLRDFRDLRDSRDFR	NCOA5	86	Q9HCD5
DRRFHRFNEDRVFDR	CSPP1	301	Q1MSJ5
EAFLLFSRRADIRRI	LRP6	631	O75581
RDADATRIDIYAERR	MORC2	41	Q9Y6X9
DREDFFAVSDCRRRF	MON1A	496	Q86VX9
ARLVRSTRFEEFLQR	OGDH	256	Q02218
SRYRDSRLRVDFERF	CAPN12	666	Q6ZSI9
RRRRFEFDFRDRDDE	GIGYF2	251	Q6Y7W6
LGVRELRIAFREFDR	CABP4	206	P57796
LRIAFREFDRDRDGR	CABP4	211	P57796
EFRDLRFVRTAEILA	DNAH3	361	Q8TD57
RGRIVEDFDREFRCL	FAM83C	286	Q9BQN1
RRFLEDKAAFEREAR	CCDC166	181	P0CW27
RLVHDFTDAVIRERR	CYP4F12	261	Q9HCS2
FRELEAERFRSRLQL	CEP95	796	Q96GE4
RSVFRDVLRAVEERD	IFRD1	336	O00458
DVRFESNFRGRLERL	CERCAM	416	Q5T4B2
DREKTDRFRLRAFAL	CDH15	111	P55291
VLREDSRAAFRLFET	C4A	1631	P0C0L4
AFEIRRLSSVFLRVR	OTOG	606	Q6ZRI0
VIRDVAQFFRVAERT	RTEL1	741	Q9NZ71
EERAERRLTARQSFV	TRMT44	346	Q8IYL2
VAERERVSRLFADAA	TRIM47	261	Q96LD4
ERRARTVRFERAAEF	PPP1R12C	41	Q9BZL4
RVFAFRETREVRGSC	TMEM132C	171	Q8N3T6
EGERDVREHAFFRRI	PRKCA	586	P17252
AAAAAESVRREARLF	MAP3K21	161	Q5TCX8
RDLEAFAERFKQRRI	POU4F2	256	Q12837
DYFRAVLQRDERSER	FNTA	101	P49354
FDTVARSEVLFRSDR	PIGQ	166	Q9BRB3
TRRTFETIFEEPRER	PRR14	491	Q9BWN1
LIDRAFSRFRHREVV	THNSL2	76	Q86YJ6
TVKERERARAAFLAR	PHF24	291	Q9UPV7
FFTRESLAAIERRIA	SCN1A	16	P35498
VFDERTADRAARLRS	ADGRD2	121	Q7Z7M1
DFRRECRDERIREYF	CLP1	291	Q92989
LVADAIRRDRFELIF	PGBD2	211	Q6P3X8
ALFRERRAVVVFVRH	PRXL2C	51	Q7RTV5
EFFDEERRARLLQFV	SMURF2	661	Q9HAU4
AFFRGRDSREERLQL	POGLUT3	311	Q7Z4H8
RYRESREERLTFVGE	TDRKH	36	Q9Y2W6
RFIRREKEIAETRFE	TPR	1201	P12270
VDRVETTRRYRLSFA	PFAS	116	O15067
RDCVRFLRAFRLRDA	NAPRT	61	Q6XQN6
DETRTLEFRRFAAED	PPP1R36	36	Q96LQ0
FLAFRERVNASREVE	PON3	21	Q15166
RRAVAEERFRLEFFV	SH2B2	226	O14492
AEVSSRFEDVRTFLR	RRP8	391	O43159
RFAKEFVDARERERI	WNT5A	191	P41221
RCAALREEFLAFRRR	IGSF9	1141	Q9P2J2
REEFLAFRRRRDATR	IGSF9	1146	Q9P2J2
AVFFLRDTERRRVFQ	nan	346	Q6ZUG5
EVDRRFSGVRRDVFL	YTHDC1	571	Q96MU7
EYEARVRARRDFQRL	VWA5B2	291	Q8N398
RRKRELRTFSFSDDE	SFMBT1	756	Q9UHJ3
REARVLEAVCEFSRR	RIPOR1	936	Q6ZS17
AFQRRFVVDVRRCEE	TCIRG1	46	Q13488
REFRAAEQEAARRIF	NAT8L	81	Q8N9F0
VRRRTFRSSEEEHEF	MYOM3	46	Q5VTT5
AERFRDAFTQELRRG	NCBP2AS2	66	Q69YL0