Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhormone binding

RXFP1 IDE ESR2

5.39e-04103313GO:0042562
GeneOntologyMolecularFunctionC-C chemokine receptor activity

CXCR6 GPR75

5.78e-0423312GO:0016493
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

CXCR6 GPR75

7.41e-0426312GO:0001637
GeneOntologyMolecularFunctionchemokine receptor activity

CXCR6 GPR75

7.41e-0426312GO:0004950
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

DNAJB1 ZNF451

1.42e-0336312GO:0140416
GeneOntologyCellularComponentpseudopodium

ACTN4 ACTN2

3.64e-0418332GO:0031143
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

ACTN4 ACTN2

4.06e-0419332GO:0098871
GeneOntologyCellularComponentpostsynaptic cytoskeleton

ACTN4 ACTN2

7.67e-0426332GO:0099571
DomainCul7

CUL9 CUL7

9.07e-063332PF11515
DomainCPH_domain

CUL9 CUL7

9.07e-063332IPR021097
DomainGalactose-bd-like

CNTNAP3 CUL9 CNTNAP3B CUL7

2.20e-0594334IPR008979
DomainEF-hand_Ca_insen

ACTN4 ACTN2

4.52e-056332IPR014837
DomainEFhand_Ca_insen

ACTN4 ACTN2

4.52e-056332PF08726
DomainAPC_su10/DOC_dom

CUL9 CUL7

6.32e-057332IPR004939
DomainAPC10

CUL9 CUL7

6.32e-057332SM01337
DomainDOC

CUL9 CUL7

6.32e-057332PS51284
DomainANAPC10

CUL9 CUL7

6.32e-057332PF03256
DomainCullin_Nedd8

CUL9 CUL7

8.42e-058332PF10557
DomainCullin_Nedd8

CUL9 CUL7

8.42e-058332SM00884
DomainCullin_neddylation_domain

CUL9 CUL7

8.42e-058332IPR019559
DomainCullin_homology

CUL9 CUL7

1.08e-049332IPR016158
DomainCullin_N

CUL9 CUL7

1.35e-0410332IPR001373
DomainCullin

CUL9 CUL7

1.35e-0410332PF00888
DomainCULLIN_2

CUL9 CUL7

1.35e-0410332PS50069
DomainCULLIN_1

CUL9 CUL7

1.35e-0410332PS01256
Domain-

CNTNAP3 CUL9 CUL7

2.87e-04733332.60.120.260
DomainRib_L2_dom2

CUL9 CUL7

4.55e-0418332IPR014722
Domain-

CUL9 CUL7

4.55e-04183322.30.30.30
DomainFA58C

CNTNAP3 CNTNAP3B

6.23e-0421332SM00231
DomainFA58C_3

CNTNAP3 CNTNAP3B

6.23e-0421332PS50022
DomainFA58C_1

CNTNAP3 CNTNAP3B

6.23e-0421332PS01285
DomainFA58C_2

CNTNAP3 CNTNAP3B

6.23e-0421332PS01286
DomainActinin_actin-bd_CS

ACTN4 ACTN2

7.48e-0423332IPR001589
DomainACTININ_2

ACTN4 ACTN2

7.48e-0423332PS00020
DomainACTININ_1

ACTN4 ACTN2

7.48e-0423332PS00019
DomainSpectrin

ACTN4 ACTN2

7.48e-0423332PF00435
DomainEGF

CNTNAP3 CNTNAP3B FRAS1 LRP1B

7.51e-04235334SM00181
DomainF5_F8_type_C

CNTNAP3 CNTNAP3B

8.15e-0424332PF00754
DomainFA58C

CNTNAP3 CNTNAP3B

8.15e-0424332IPR000421
DomainEGF-like_dom

CNTNAP3 CNTNAP3B FRAS1 LRP1B

9.31e-04249334IPR000742
DomainSpectrin_repeat

ACTN4 ACTN2

1.19e-0329332IPR002017
DomainFibrinogen_a/b/g_C_dom

CNTNAP3 CNTNAP3B

1.45e-0332332IPR002181
DomainFIBRINOGEN_C_2

CNTNAP3 CNTNAP3B

1.45e-0332332PS51406
DomainSpectrin/alpha-actinin

ACTN4 ACTN2

1.45e-0332332IPR018159
DomainSPEC

ACTN4 ACTN2

1.45e-0332332SM00150
DomainFIBRINOGEN_C_1

CNTNAP3 CNTNAP3B

1.45e-0332332PS00514
DomainLAM_G_DOMAIN

CNTNAP3 CNTNAP3B

2.05e-0338332PS50025
DomainLaminin_G_2

CNTNAP3 CNTNAP3B

2.26e-0340332PF02210
DomainLDLR_class-A_CS

RXFP1 LRP1B

2.26e-0340332IPR023415
DomainLamG

CNTNAP3 CNTNAP3B

2.73e-0344332SM00282
DomainLdl_recept_a

RXFP1 LRP1B

2.86e-0345332PF00057
Domain-

RXFP1 LRP1B

2.98e-03463324.10.400.10
DomainLDLRA_1

RXFP1 LRP1B

3.25e-0348332PS01209
DomainLDrepeatLR_classA_rpt

RXFP1 LRP1B

3.38e-0349332IPR002172
DomainLDLa

RXFP1 LRP1B

3.38e-0349332SM00192
DomainLDLRA_2

RXFP1 LRP1B

3.38e-0349332PS50068
DomainLaminin_G

CNTNAP3 CNTNAP3B

4.70e-0358332IPR001791
DomainCH

ACTN4 ACTN2

5.87e-0365332SM00033
DomainCH

ACTN4 ACTN2

6.78e-0370332PF00307
Domain-

CUL9 CUL7 WDFY4

6.95e-032223331.25.10.10
Domain-

ACTN4 ACTN2

6.97e-03713321.10.418.10
DomainCH

ACTN4 ACTN2

7.36e-0373332PS50021
DomainCH-domain

ACTN4 ACTN2

7.75e-0375332IPR001715
DomainEGF_3

CNTNAP3 CNTNAP3B LRP1B

8.12e-03235333PS50026
DomainEGF_1

CNTNAP3 CNTNAP3B LRP1B

1.01e-02255333PS00022
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

IRF8 ACTN4 ACTN2 CPQ OR52A1

5.75e-0717133520201926
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3 CNTNAP3B

8.73e-07233231150793
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3 CNTNAP3B

8.73e-07233226807827
Pubmed

Colocalization of α-actinin and synaptopodin in the pyramidal cell axon initial segment.

ACTN4 ACTN2

2.62e-06333221940706
Pubmed

A novel p53-binding domain in CUL7.

CUL9 CUL7

2.62e-06333216875676
Pubmed

Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.

CUL9 CUL7

2.62e-06333217229476
Pubmed

Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.

CUL9 CUL7

2.62e-06333215964813
Pubmed

The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.

CUL9 CUL7

2.62e-06333217298945
Pubmed

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.

ACTN4 ACTN2

2.62e-0633328104223
Pubmed

The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.

ACTN4 ACTN2

2.62e-06333210656685
Pubmed

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

ACTN4 ACTN2

5.23e-06433216807302
Pubmed

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.

ACTN4 ACTN2

5.23e-0643321629252
Pubmed

Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptors.

ACTN4 ACTN2

5.23e-06433216510730
Pubmed

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.

ACTN4 ACTN2

8.72e-06533212837758
Pubmed

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.

ACTN4 ACTN2

8.72e-06533219943616
Pubmed

CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.

CUL9 CUL7

8.72e-06533224793696
Pubmed

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

ACTN4 ACTN2

8.72e-06533215841212
Pubmed

PARC and CUL7 form atypical cullin RING ligase complexes.

CUL9 CUL7

8.72e-06533217332328
Pubmed

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

ACTN4 ACTN2

1.31e-05633218425115
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3 CNTNAP3B

1.31e-05633234143959
Pubmed

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.

ACTN4 ACTN2

1.31e-05633222693585
Pubmed

Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.

ACTN4 ACTN2

1.83e-05733211724819
Pubmed

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.

ACTN4 ACTN2

2.44e-05833220215401
Pubmed

Mice deficient in alpha-actinin-4 have severe glomerular disease.

ACTN4 ACTN2

2.44e-05833212782671
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

ACTN4 ACTN2

3.91e-051033220368620
Pubmed

Origin, fate and dynamics of macrophages at central nervous system interfaces.

IRF8 MRC1

3.91e-051033227135602
Pubmed

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.

CUL9 CUL7

4.78e-051133231570706
Pubmed

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.

ACTN4 ACTN2

5.73e-051233215465019
Pubmed

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.

CUL9 CUL7

7.89e-051433222653443
Pubmed

Filamin C is Essential for mammalian myocardial integrity.

ACTN4 ACTN2

7.89e-051433236706168
Pubmed

Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

ACTN4 ACTN2

9.10e-051533211440986
Pubmed

Genome-wide association study of chronic periodontitis in a general German population.

SEMA6A ACTN2 LRP1B

1.05e-049633324024966
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3 CNTNAP3B

1.18e-041733226389685
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DNAJB1 NHS ARHGEF28 YTHDF2 NSD3 NCKIPSD

1.42e-0486133636931259
Pubmed

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.

DNAJB1 ACTN4 ACTN2

1.61e-0411133321163940
Pubmed

Use of (alternative) coreceptors for HIV entry.

MRC1 CXCR6

1.81e-042133222842622
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3 CNTNAP3B

1.99e-042233226494785
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

CUL9 CUL7

2.38e-042433233705438
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

CUL9 SEMA6A CUL7

2.56e-0413033312421765
Pubmed

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.

ACTN4 ACTN2

3.02e-042733236899856
Pubmed

Specification of CNS macrophage subsets occurs postnatally in defined niches.

IRF8 MRC1

3.02e-042733235444273
Pubmed

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice.

ACTN4 ACTN2

3.25e-042833230947518
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

CNTNAP3 CNTNAP3B

3.49e-042933231491374
Pubmed

Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.

ARHGEF28 ESR2

3.74e-043033238310234
Pubmed

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.

ACTN4 ACTN2

3.99e-043133214630798
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DNAJB1 NHS ACTN4 IDE CUL7 NSD3

4.09e-04104933627880917
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CUL9 FRAS1 SGSM2 ZNF451

5.78e-0440733412693553
InteractionRLN1 interactions

CNTNAP3 CNTNAP3B SEMA6A RXFP1 LRP1B

2.90e-0793315int:RLN1
InteractionCST9L interactions

CNTNAP3 CNTNAP3B SEMA6A CUL7

6.03e-0678314int:CST9L
InteractionFEZF1 interactions

CUL9 CUL7 LRP1B

1.05e-0528313int:FEZF1
InteractionPDLIM1 interactions

ACTN4 ACTN2 CUL7 RHBDF2

1.38e-0596314int:PDLIM1
InteractionRALY interactions

DNAJB1 CUL9 ACTN4 ACTN2 CUL7 ESR2

1.48e-05356316int:RALY
InteractionFBXO2 interactions

CNTNAP3 CNTNAP3B FRAS1 SEMA6A CUL7 LRP1B

3.32e-05411316int:FBXO2
InteractionEFHD2 interactions

DNAJB1 RHBDF2 WDFY4 ESR2

4.15e-05127314int:EFHD2
InteractionTPM4 interactions

IRF8 ACTN4 ACTN2 CUL7 ESR2

4.36e-05259315int:TPM4
InteractionTPM1 interactions

IRF8 ACTN4 ACTN2 WDFY4 ESR2

4.69e-05263315int:TPM1
InteractionHSPA1L interactions

DNAJB1 CUL7 DIS3 ESR2 NCKIPSD

7.33e-05289315int:HSPA1L
InteractionTRGV3 interactions

CNTNAP3 CNTNAP3B FRAS1

8.19e-0555313int:TRGV3
InteractionMAPK11 interactions

CUL7 YTHDF2 ESR2

8.64e-0556313int:MAPK11
InteractionAHNAK interactions

ACTN4 CUL7 RHBDF2 WDFY4 DIS3

1.15e-04318315int:AHNAK
InteractionIGKV2D-28 interactions

CUL9 CUL7

1.50e-0412312int:IGKV2D-28
InteractionPTPRK interactions

CNTNAP3 FRAS1 LRP1B ESR2

1.50e-04177314int:PTPRK
InteractionACTN1 interactions

ACTN4 ACTN2 CUL7 WDFY4 ESR2

1.59e-04341315int:ACTN1
InteractionARPC2 interactions

ACTN4 CUL7 WDFY4 ESR2

1.86e-04187314int:ARPC2
InteractionYWHAH interactions

DNAJB1 NHS ARHGEF28 RHBDF2 YTHDF2 ESR2 NSD3 NCKIPSD

1.99e-041102318int:YWHAH
InteractionRNASE4 interactions

CNTNAP3 LRP1B

2.06e-0414312int:RNASE4
InteractionRAVER1 interactions

ACTN4 ACTN2 DIS3 ESR2

2.14e-04194314int:RAVER1
InteractionZBTB17 interactions

IRF8 DIS3 ESR2

2.23e-0477313int:ZBTB17
Cytoband3p21

CXCR6 NCKIPSD

2.61e-04333323p21
Cytoband6p21.1

CUL9 CUL7

1.53e-03803326p21.1
GeneFamilyActinins

ACTN4 ACTN2

9.27e-0642321112
GeneFamilyCullins

CUL9 CUL7

4.31e-0582321032
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MRC1 CXCR6 ENPP3

1.32e-02394233471
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

1.88e-071763350710689e66deba179b0a8038cdd56b4834984f12
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

1.99e-071783356f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

2.04e-071793351ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

2.16e-071813359de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellNeuronal-Excitatory-eF(C1QL3)|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

3.54e-072003357668ae7ed550583ab59e419c5c9bb9f2d7e8e0d5
ToppCellNeuronal-Excitatory-eF(C1QL3)----L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

3.54e-0720033544f0278cb0e4ffcda4af3719d7f5819a10929b9f
ToppCellNeuronal-Excitatory-eF(C1QL3)---|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

3.54e-0720033523da7790e09575b2ca909ed16806b44223bf1017
ToppCellNeuronal-Excitatory-eF(C1QL3)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

3.54e-0720033591f3df1c5a661ff703835f58a35cee93f18eb15c
ToppCellNeuronal-Excitatory-eF(C1QL3)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 RXFP1 ACTN2 ARHGEF28 LRP1B

3.54e-072003352e2b1d252972b702ade25526ec8461bf613d81b0
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN2 CUL7 CXCR6 ZNF451

6.26e-06163334953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B RXFP1 ACTN2

7.92e-0617333495c723b09254ae7131fe5ba0841472502e83269b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIPK1B MRC1 SEMA6A ENPP3

8.47e-06176334057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIPK1B MRC1 SEMA6A ENPP3

8.47e-06176334b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 ACTN2 ARHGEF28 LRP1B

8.67e-06177334921783ed0fe20294d2f384d9136924b679df01bb
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 RXFP1 ARHGEF28 LRP1B

8.67e-06177334f30d757ee8db7e10d547498dab6560473c6ed7c0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 ACTN2 ARHGEF28 LRP1B

9.06e-06179334445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3 CNTNAP3B NHS ESR2

9.06e-0617933414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell(2)_NK/T-(230)_CD4+/CD25+_Reg_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

MRC1 CUL9 WDFY4 NSD3

9.46e-06181334ad14c7111d4fb924afd233cb114447f195373a7c
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3B NHS ARHGEF28 ENPP3

9.46e-061813346980ea624151da32b7f537f263e40fcb87a02e81
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP3 FRAS1 PRMT8 ACTN2

9.67e-06182334d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP3 FRAS1 PRMT8 ACTN2

9.67e-061823346cde859edfe7607bd7ada89d20258413d06f4207
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NHS FRAS1 ARHGEF28 LRP1B

9.67e-061823349d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.01e-05184334371c1927ac06b77ff462a94cca6acb802f9724ff
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.01e-05184334fbac70333e4f028bfbdd9cc9401427caac9f0c47
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.01e-05184334dd6777a0cb49cd79fc439920c3c930a1e4681bb0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.03e-051853346b832b3e080dfadd21253ac45022192f4d3cb37b
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 DIPK1B CNTNAP3B RXFP1

1.03e-05185334a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.05e-05186334e41f14aee8cfbf76b8d0d4695a6170e2cd92aec8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.05e-05186334b3633cd4e360c5b45060c50b4f606d483e03a89a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.05e-051863349dd31dc9af1704f35c74de726a6c27fa21e9a014
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.08e-0518733423a42c172d5cc36cb8793c0bc2ce357c6c8e5d39
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.08e-051873345ce7cf02990465b6f793205e4be07e8337b3570a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 CNTNAP3B SEMA6A RXFP1

1.08e-05187334e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.08e-0518733417a37fc3a1d62fef3137e5ff26a84c0b8c80e124
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.08e-051873341b0eb29394040555516677b9de75c15e769c4c53
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

NHS FRAS1 ARHGEF28 LRP1B

1.08e-05187334d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.08e-0518733411c773cf3dc1e725b7e4d8edd676c8a94a231d2a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-0518833426c0a94951236a5d17a169920b0a8a9d0dd7d0ed
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-05188334af300574c4e95505f56bf716bcee1e4777944e8e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-051883345df5a0890e17d19f55770525345a656253696887
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-05188334c65fb9a3c910dd6166853f4f3a2f2c2411ccf03b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-05188334e169e9bb85892e52880ee949d0f691d0ea0c8dc9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-051883349e923b0d79495ee1a3a097741a877f25d439eda3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.10e-0518833414dbc985abc2012c9f53deb243d465e4175f419f
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IRF8 MRC1 ARHGEF28 WDFY4

1.10e-05188334d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.12e-05189334389ccb68acb82893709f256315111470cf4beed3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.12e-0518933458465b9407fbce91cca8f199950d6e0054c38fbc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHS ACTN4 RXFP1 LRP1B

1.12e-051893348c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHS ACTN4 RXFP1 LRP1B

1.12e-051893345d902a4660a27548764bf04c6de152b565da835c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.12e-05189334e9fe8d17f4b7cca9bbf3655047e27b2fec5060c1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.12e-051893347ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRF8 MRC1 RHBDF2 WDFY4

1.15e-05190334d4f954e0748898df69e1710df558564db703dd61
ToppCellCOVID-19_Severe-B_intermediate|World / disease group, cell group and cell class

CNTNAP3 IRF8 CNTNAP3B WDFY4

1.17e-05191334f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DNAJB1 NHS SEMA6A LRP1B

1.19e-05192334d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3 MRC1 CNTNAP3B SEMA6A

1.19e-05192334cbe57cda44232b183821ac633b60a2668265e616
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|tumor_Lung / Location, Cell class and cell subclass

CNTNAP3 CNTNAP3B SEMA6A RXFP1

1.22e-0519333421fec35587ffb5c0157e54a821ce3ffd3e24e536
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHS FRAS1 ARHGEF28 LRP1B

1.22e-0519333482e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DIPK1B CNTNAP3B SEMA6A RXFP1

1.22e-05193334ff6e6b825d6c88148216c601580be3c28851ab5c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DIPK1B CNTNAP3B SEMA6A RXFP1

1.24e-05194334fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF8 MRC1 RHBDF2 WDFY4

1.27e-0519533491a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IRF8 MRC1 RHBDF2 WDFY4

1.27e-05195334247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NHS FRAS1 ARHGEF28 LRP1B

1.27e-051953346477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRF8 MRC1 RHBDF2 WDFY4

1.29e-05196334cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellEndothelial-capillary_endothelial_cell_(Cap1)|World / Lineage, Cell type, age group and donor

DIPK1B CNTNAP3B SEMA6A RXFP1

1.29e-051963340ce3ed27d2b9276390952652c17a8d6de13add36
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF8 MRC1 WDFY4 LRP1B

1.32e-0519733489fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DIPK1B CNTNAP3B SEMA6A RXFP1

1.32e-051973346a3c647af41fea923311562575a0d656fbc13cbe
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF8 MRC1 WDFY4 LRP1B

1.35e-05198334898ef4f02443780f9b1fc08b73a165fda0ca5cde
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF8 MRC1 WDFY4 LRP1B

1.35e-0519833442be18aef4f656a86c61630b061826a858c496fd
ToppCell367C|World / Donor, Lineage, Cell class and subclass (all cells)

MRC1 DNAJB1 CPQ CXCR6

1.35e-05198334ab3a178f392204e2d90eb5a3b5de7849986b1eaf
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3 MRC1 CNTNAP3B SEMA6A

1.35e-05198334b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3 MRC1 CNTNAP3B SEMA6A

1.35e-05198334fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.37e-0519933498c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.37e-0519933454167894a16e975d0541cbe3e515bcfa183044f6
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.37e-051993341413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.37e-05199334b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.37e-051993346ce7612ee2ae211eb0f73391e96089ad5431c537
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.40e-05200334ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.40e-05200334f3dc07a7cc8cf041da8fe610d21af595818cf2d8
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.40e-05200334ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 CNTNAP3B RXFP1 LRP1B

1.40e-05200334e3051dcf9b5c8e4dc71a8080b7a7aafea46f2b2b
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO--|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 CNTNAP3B RXFP1 LRP1B

1.40e-052003341ce9599cc9d8158e8842ca56f35fa7809c234849
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.40e-0520033478d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 CNTNAP3B RXFP1 LRP1B

1.40e-052003347b845aabfbdfe893acc9334a5707833761bed60b
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IRF8 MRC1 RHBDF2 WDFY4

1.40e-0520033448ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 CNTNAP3B RXFP1 LRP1B

1.40e-052003340638273fc0910f47fe7a0b6d9a8639b0e9976d13
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DNAJB1 RHBDF2 CXCR6

6.05e-05103333e28236a064a7c86e99e7e2edb1eb777f6034a9b4
ToppCellcontrol-Myeloid-Monocyte-derived_DC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ACTN4 DIS3 YTHDF2

6.96e-05108333e74e73d89d78c8d59dfdd2bd30db54b366a49d23
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MRC1 WDFY4 ENPP3

7.76e-051123339801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IRF8 WDFY4 NSD3

1.23e-04131333a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-mDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRF8 MRC1 WDFY4

1.26e-04132333f8e2ba53063007d7507f1837ad669b0e4333cd23
ToppCellmetastatic_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

FRAS1 SEMA6A ACTN2

1.44e-04138333b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEMA6A CXCR6 NCKIPSD

1.50e-041403337b359bfbd404ab06d799048252f4985d85852048
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IRF8 RXFP1 LRP1B

1.50e-04140333c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 NHS SEMA6A

1.63e-0414433371107275767a0728541a3695715c44874b3e5efc
ToppCellLPS_only-Myeloid-Dendritic_cells-mDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRF8 MRC1 WDFY4

1.74e-0414733326bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3 CNTNAP3B SEMA6A

1.77e-04148333f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRF8 MRC1 WDFY4

1.77e-04148333cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor|bone_marrow / Manually curated celltypes from each tissue

DIPK1B ACTN2 OR52A1

1.81e-04149333078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCellsevere_influenza-Treg|World / disease group, cell group and cell class (v2)

MRC1 ENPP3 GPR75

1.81e-041493332a3a00cdf604c8f3f3863df0ddb06938549bf86d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 NHS RXFP1

1.88e-04151333090b067873740c282865e2d02cf47d5cb3dd7607
Diseasesemaphorin-6A measurement

MRC1 SEMA6A

6.83e-064322EFO_0020721
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN4 ACTN2

1.14e-055322DOID:0111128 (implicated_via_orthology)
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3 CNTNAP3B

3.18e-058322DOID:0060308 (implicated_via_orthology)
DiseasePapillary Renal Cell Carcinoma

CUL7 CPQ LRP1B

3.61e-04128323C1306837
DiseaseRenal Cell Carcinoma

CUL7 CPQ LRP1B

3.61e-04128323C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

CUL7 CPQ LRP1B

3.61e-04128323C1266043
DiseaseChromophobe Renal Cell Carcinoma

CUL7 CPQ LRP1B

3.61e-04128323C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

CUL7 CPQ LRP1B

3.61e-04128323C1266044
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CUL7 CPQ LRP1B

5.51e-04148323C0279702
Diseaserectum cancer

WDFY4 LRP1B

9.55e-0442322EFO_1000657
Diseasecup-to-disc ratio measurement

DNAJB1 FRAS1 ACTN4 NCKIPSD

1.16e-03430324EFO_0006939
Diseasesystemic lupus erythematosus (is_implicated_in)

IRF8 ESR2

2.07e-0362322DOID:9074 (is_implicated_in)
DiseaseC-X-C motif chemokine 10 measurement

FRAS1 ARHGEF28

6.24e-03109322EFO_0008056

Protein segments in the cluster

PeptideGeneStartEntry
TGSSMTYHFQEHYTL

CNTNAP3

1006

Q9BZ76
MTYVSCFYHAFAGAE

ACTN2

246

P35609
LYKYFFFHHSHGDTM

CPQ

426

Q9Y646
MAEHDYHEDYGFSSF

CXCR6

1

O00574
THWEYYAMTSFHYTI

CXCR6

256

O00574
AIMTYVSSFYHAFSG

ACTN4

256

O43707
YFDSYAHFGIHEEML

PRMT8

76

Q9NR22
FVEELFHGSYGTFYM

DIPK1B

281

Q5VUD6
SYTFHGDPHAMFAEF

DNAJB1

91

P25685
EFYFTYDGSHQRHVM

ARHGEF28

31

Q8N1W1
EHHTEMEFSFFYDTV

FRAS1

3491

Q86XX4
TDHSRMHWFSYYTTH

LRP1B

3986

Q9NZR2
YVDSHHEYPAMTFYS

ESR2

36

Q92731
GYTTYDAHHSAFSQM

IRF8

191

Q02556
FYHTTVISHSYCEHM

OR52A1

171

Q9UKL2
ATTFEHYYQHYMADR

CUL7

1261

Q14999
FGFANSYIAMHYHTT

GPR75

506

O95800
FYTMYFEEPDSSGHA

ENPP3

316

O14638
TTFEHFYQHYMADRL

CUL9

1591

Q8IWT3
FTSGEHTNYYFDVSH

IDE

141

P14735
TGSSMTYHFQEHYTL

CNTNAP3B

1006

Q96NU0
HHFYCYMIGHTLSTF

MRC1

511

P22897
HFSVDTEGYYTSMHF

NHS

776

Q6T4R5
FELMHQNGDYTHFYF

SGSM2

896

O43147
AVYFCSGMDNDFHHY

DIS3

751

Q9Y2L1
VFSMGEAVPYAHYEH

NCKIPSD

511

Q9NZQ3
TEFHNGHRYFYEMDE

ZNF451

551

Q9Y4E5
YYSSSFAQHMRIHTG

ZNF599

321

Q96NL3
MHHSSSYGVDYKRSY

SEMA6A

906

Q9H2E6
TEGDMTVQCHYYTHY

WDFY4

2621

Q6ZS81
VFSYGSMFYSVHQSA

RXFP1

596

Q9HBX9
DHSDPMFSSYAYKSH

NSD3

876

Q9BZ95
TTREYCEFMHGYFHE

RHBDF2

611

Q6PJF5
SYKHTTSIFDDFSHY

YTHDF2

546

Q9Y5A9