Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TET2 ERG MBTPS2 ASCL1 PITX1 CRTC1 ELF3 SSBP2 SSBP3 ZBTB7B NFAT5 NIPBL NOTCH1 TP73 VDR

2.55e-0513906615GO:0045944
GeneOntologyBiologicalProcesshead development

SCHIP1 AVPR1A ASCL1 SLIT3 SEC24B PITX1 POU3F4 UPF3B SSBP3 NIPBL NOTCH1 TP73

3.04e-059196612GO:0060322
GeneOntologyCellularComponentchromatin

ZBTB34 SP2 ARID1B ERG ASCL1 PITX1 ANKRD17 ELF3 POU3F4 MAP3K7 NFAT5 NIPBL TP73 VDR

1.77e-0414806614GO:0000785
GeneOntologyCellularComponentcaveola

KCND3 IRS1 F2R VDR

4.21e-04111664GO:0005901
DomainSSDP_DNA-bd

SSBP2 SSBP3

3.57e-053652IPR008116
Pubmed

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.

GAD1 ASCL1 POU3F4 NOTCH1

1.93e-072668412397111
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 BMX PTPN13 UBAP2 SEC24B ANKRD17 CRTC1 IRS1 CRYBG3 WNK3 DOP1B

8.51e-07861681136931259
Pubmed

p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1.

NOTCH1 TP73

3.77e-06268235617425
Pubmed

Sodium and potassium regulate endothelial phospholipase C-γ and Bmx.

BMX PLCG1

3.77e-06268224785188
Pubmed

Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells.

PTPN13 IRS1

3.77e-06268212354757
Pubmed

Mash1-expressing cells could differentiate to type III cells in adult mouse taste buds.

GAD1 ASCL1

3.77e-06268229525940
Pubmed

Hypermethylation of adjacent CpG sites is negatively correlated with the expression of lineage oncogene ASCL1 in pulmonary neuroendocrine tumors.

ASCL1 NOTCH1

3.77e-06268228621224
Pubmed

An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.

ASCL1 ELF3

3.77e-06268236840413
Pubmed

Chemotactic Cues for NOTCH1-Dependent Leukemia.

CCR9 NOTCH1

3.77e-06268229666622
Pubmed

Small cell lung cancer, an epithelial to mesenchymal transition (EMT)-like cancer: significance of inactive Notch signaling and expression of achaete-scute complex homologue 1.

ASCL1 NOTCH1

3.77e-06268227785690
Pubmed

Phospholipase Cγ1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity.

PLCG1 NOTCH1

3.77e-06268228698260
Pubmed

The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation.

PTPN13 IRS1

3.77e-06268217638892
Pubmed

Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP.

PLCG1 NFAT5

3.77e-06268220080774
Pubmed

Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

BMX F2R

3.77e-06268220559570
Pubmed

Gene expression in cortical interneuron precursors is prescient of their mature function.

GAD1 POU3F4 SSBP2

6.77e-061968318250082
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

SP2 ELOA2 ERG ASCL1 POU3F4 SSBP2 SSBP3 ZBTB7B TP73 VDR

7.66e-06877681020211142
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TET2 ARID1B UBAP2 SLIT3 HECTD4 ANKRD17 CRTC1 DEPDC5

9.02e-0652968814621295
Pubmed

A census of human transcription factors: function, expression and evolution.

SP2 ERG ASCL1 PITX1 ELF3 POU3F4 ZBTB7B NFAT5 TP73 VDR

1.03e-05908681019274049
Pubmed

Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon.

GAD1 ASCL1 POU3F4

1.07e-052268311124115
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SP2 ERG ASCL1 PITX1 ELF3 POU3F4 ZBTB7B NFAT5

1.10e-0554468828473536
Pubmed

1,25(OH)2D3 induces regulatory T cell differentiation by influencing the VDR/PLC-γ1/TGF-β1/pathway.

PLCG1 VDR

1.13e-05368228926770
Pubmed

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia.

CCR9 NOTCH1

1.13e-05368221984373
Pubmed

Ssdp proteins bind to LIM-interacting co-factors and regulate the activity of LIM-homeodomain protein complexes in vivo.

SSBP2 SSBP3

1.13e-05368212642495
Pubmed

IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.

SCHIP1 IQCJ-SCHIP1

1.13e-05368217045569
Pubmed

BMX Represses Thrombin-PAR1-Mediated Endothelial Permeability and Vascular Leakage During Early Sepsis.

BMX F2R

1.13e-05368231910739
Pubmed

Conservation of the Notch1 signaling pathway in gastrointestinal carcinoid cells.

ASCL1 NOTCH1

1.13e-05368216160079
Pubmed

TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.

ERG NOTCH1

1.13e-05368228783165
Pubmed

Differential regulation of vitamin D receptor (VDR) by the p53 Family: p73-dependent induction of VDR upon DNA damage.

TP73 VDR

1.13e-05368217716971
Pubmed

p42(IP4)/centaurin alpha1, a brain-specific PtdIns(3,4,5)P3/Ins(1,3,4,5)P4-binding protein: membrane trafficking induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor.

PLCG1 F2R

1.13e-05368216341594
Pubmed

Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system.

ASCL1 NOTCH1

1.13e-0536828217843
Pubmed

Notch signaling induces rapid degradation of achaete-scute homolog 1.

ASCL1 NOTCH1

1.13e-05368211940670
Pubmed

The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner.

BMX MAP3K7

1.13e-05368221471444
Pubmed

A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.

SSBP2 SSBP3

1.13e-05368212079286
Pubmed

Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.

GAD1 CADPS2

1.13e-05368221173225
Pubmed

MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis.

ASCL1 NOTCH1

1.13e-05368227705795
Pubmed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

SLIT3 CRTC1 CADPS2 NFAT5 VDR

1.13e-0514968525231870
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

NAT2 IRS1 VDR

1.59e-052568318992263
Pubmed

Human transcription factor protein interaction networks.

TET2 SP2 ARID1B UBAP2 ERG SEC24B PITX1 ANKRD17 ELF3 SSBP2 SSBP3 NIPBL

1.91e-051429681235140242
Pubmed

Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.

SCHIP1 IQCJ-SCHIP1

2.25e-05468227979964
Pubmed

Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development.

SSBP2 SSBP3

2.25e-05468212381786
Pubmed

WNT7B represses epithelial-mesenchymal transition and stem-like properties in bladder urothelial carcinoma.

ELF3 NOTCH1

2.25e-05468234562599
Pubmed

The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling.

ERG VDR

2.25e-05468224926821
Pubmed

REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma.

ASCL1 POU3F4

2.25e-05468235367201
Pubmed

Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study.

ERG NOTCH1

2.25e-05468221835957
Pubmed

Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1.

NOTCH1 TP73

2.25e-05468231712410
Pubmed

The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development.

CCR9 NOTCH1

2.25e-05468218458114
Pubmed

Fast, high-throughput production of improved rabies viral vectors for specific, efficient and versatile transsynaptic retrograde labeling.

GAD1 ASCL1

2.25e-05468236040301
Pubmed

Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.

GAD1 ASCL1 POU3F4

2.26e-052868330796806
Pubmed

Impaired Interneuron Development after Foxg1 Disruption.

GAD1 ASCL1 NOTCH1

2.52e-052968326620267
Pubmed

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.

GAD1 ASCL1 NOTCH1

2.52e-052968317928865
Pubmed

Developmental diversification of cortical inhibitory interneurons.

GAD1 ASCL1 POU3F4 NOTCH1

3.14e-059168429513653
Pubmed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

BMX IRS1 PLCG1

3.40e-053268322974441
Pubmed

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

NAT2 IRS1 VDR

3.40e-053268320437058
Pubmed

Insulin-like growth factor pathway polymorphisms associated with body size in Hispanic and non-Hispanic white women.

IRS1 VDR

3.75e-05568216030120
Pubmed

Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.

SCHIP1 IQCJ-SCHIP1

3.75e-05568218550753
Pubmed

ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK).

IRS1 PLCG1

3.75e-0556829174053
Pubmed

Mutations in DEPDC5 cause familial focal epilepsy with variable foci.

GAD1 DEPDC5

3.75e-05568223542697
Pubmed

Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas.

ASCL1 NOTCH1

3.75e-05568220515335
Pubmed

Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling.

MAP3K7 NFAT5

3.75e-05568218332137
Pubmed

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.

SCHIP1 IQCJ-SCHIP1

3.75e-05568225950943
Pubmed

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.

ASCL1 NOTCH1

3.75e-05568211564735
Pubmed

Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways.

ASCL1 NOTCH1

3.75e-05568223526493
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

ASCL1 NOTCH1

3.75e-05568212242712
Pubmed

Deubiquitinase USP18 promotes the progression of pancreatic cancer via enhancing the Notch1-c-Myc axis.

MAP3K7 NOTCH1

3.75e-05568233051403
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

HECTD4 ANKRD17 CRTC1 DEPDC5

4.92e-051026849734811
Pubmed

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.

CRTC1 NOTCH1

5.62e-05668223832089
Pubmed

PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).

IRS1 VDR

5.62e-05668216489531
Pubmed

Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain.

GAD1 CDH12

5.62e-05668220723620
Pubmed

Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.

MAP3K7 NOTCH1

5.62e-05668229228365
Pubmed

Diazepam binding inhibitor governs neurogenesis of excitatory and inhibitory neurons during embryonic development via GABA signaling.

GAD1 ASCL1

5.62e-05668235998632
Pubmed

Expression of GAD67 and Dlx5 in the taste buds of mice genetically lacking Mash1.

GAD1 ASCL1

5.62e-05668224682237
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SP2 ERG ELF3 POU3F4 ZBTB7B NFAT5 PDLIM5 VDR

7.22e-0570968822988430
Pubmed

Parcellation of the striatal complex into dorsal and ventral districts.

ASCL1 POU3F4 NOTCH1

7.77e-054268332170006
Pubmed

Oscillatory control of factors determining multipotency and fate in mouse neural progenitors.

ASCL1 NOTCH1

7.86e-05768224179156
Pubmed

Notch pathway activation targets AML-initiating cell homeostasis and differentiation.

TET2 NOTCH1

7.86e-05768223359070
Pubmed

Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions.

IRS1 VDR

7.86e-05768218059035
Pubmed

Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.

MAP3K7 NOTCH1

7.86e-05768225535389
Pubmed

Pulmonary neuroendocrine cells function as airway sensors to control lung immune response.

GAD1 ASCL1 SLIT3

1.02e-044668326743624
Pubmed

A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development.

ASCL1 NOTCH1

1.05e-04868210512199
Pubmed

Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality.

ASCL1 NOTCH1

1.05e-04868210393120
Pubmed

Widespread defects in the primary olfactory pathway caused by loss of Mash1 function.

GAD1 ASCL1

1.05e-04868212629181
Pubmed

Ascl1 participates in Cajal-Retzius cell development in the neocortex.

ASCL1 TP73

1.05e-04868221467208
Pubmed

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.

SLC4A4 WNK3

1.05e-04868221317537
Pubmed

Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip.

ASCL1 NOTCH1

1.34e-04968217319963
Pubmed

Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium.

ASCL1 NOTCH1

1.34e-04968217605079
Pubmed

Characterization of the Abracl-Expressing Cell Populations in the Embryonic Mammalian Telencephalon.

GAD1 ASCL1

1.34e-04968237759737
Pubmed

Consequence of the loss of Sox2 in the developing brain of the mouse.

ASCL1 NOTCH1

1.34e-04968218638478
Pubmed

Tyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signaling by insulin.

IRS1 PLCG1

1.34e-04968210455176
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

AVPR1A PITX1 PRKAG1 SSBP3 CADPS2 ZBTB7B

1.37e-0440268624722188
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 ABCG1 PTPN13 KCND3 HECTD4 PRKAG1 ANKRD17 PLCG1 SSBP3 NFAT5 NSMAF

1.39e-041489681128611215
Pubmed

Making sense of Dlx1 antisense RNA.

GAD1 ASCL1

1.68e-041068223415800
Pubmed

Regulation of GATA-3 expression during CD4 lineage differentiation.

ZBTB7B NFAT5

1.68e-041068221357543
Pubmed

A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool.

ASCL1 NOTCH1

1.68e-041068217728344
Pubmed

Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus.

GAD1 ASCL1

1.68e-041068227929058
Pubmed

Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis.

ASCL1 NOTCH1

1.68e-041068223695674
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SP2 ELF3 PLCG1 ZBTB7B NFAT5 PDLIM5 DOP1B VDR

1.77e-0480868820412781
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TET2 PTPN13 ERG ASCL1 HECTD4 PLCG1 CADPS2 NIPBL PDLIM5 DOP1B

1.90e-041285681035914814
Pubmed

MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors.

GAD1 ASCL1 TP73

1.94e-045768321368052
Pubmed

Hoxb1 controls anteroposterior identity of vestibular projection neurons.

GAD1 ASCL1

2.05e-041168222485187
Pubmed

CXCR7 Receptor Controls the Maintenance of Subpial Positioning of Cajal-Retzius Cells.

GAD1 TP73

2.05e-041168225085881
InteractionYWHAH interactions

TET2 PTPN13 UBAP2 LRCH2 NHSL2 SEC24B HECTD4 ANKRD17 CRTC1 IRS1 CRYBG3 MAP3K7 WNK3 DOP1B

1.51e-0511026814int:YWHAH
InteractionJAK1 interactions

MANSC1 ELF3 IRS1 UPF3B PLCG1 CMKLR1 ZBTB7B

2.01e-05248687int:JAK1
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BMX IRS1 PLCG1 CADPS2

1.31e-03206424682
GeneFamilyETS transcription factor family

ERG ELF3

1.92e-0328422534
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SCHIP1 PTPN13 DDR2 SEC24B UGCG ANKRD17 SSBP2 IRS1 CRYBG3 NIPBL PDLIM5 NSMAF DOP1B

2.62e-078566813M4500
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

SP2 ERG AVPR1A KCND3 ASCL1 CCR9 POU3F4 SSBP2 SLC4A4 PDLIM5 TP73 VDR

3.43e-069096812M41018
CoexpressionGSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN

PTPN13 CCR9 SSBP2 ZBTB7B F2R NOTCH1

1.31e-05199686M8542
CoexpressionBENPORATH_ES_WITH_H3K27ME3

PRUNE2 TET2 BMX LRCH2 KCND3 ASCL1 SLIT3 PITX1 POU3F4 F2R TP73 VDR

2.66e-0511156812M10371
CoexpressionBENPORATH_PRC2_TARGETS

TET2 LRCH2 KCND3 ASCL1 PITX1 POU3F4 F2R TP73 VDR

4.49e-05650689M8448
CoexpressionLU_AGING_BRAIN_UP

ABCG1 PTPN13 ASCL1 SLC4A4 NIPBL PDLIM5

6.27e-05263686M5547
CoexpressionBENPORATH_SUZ12_TARGETS

TET2 BMX ERG LRCH2 KCND3 ASCL1 PITX1 POU3F4 F2R TP73 VDR

6.72e-0510356811M9898
CoexpressionCARRILLOREIXACH_MRS3_VS_LOWER_RISK_HEPATOBLASTOMA_DN

PTPN13 LRCH2 DDR2 SSBP2 CRYBG3

7.67e-05168685M45039
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP

PTPN13 UPF3B CMKLR1 F2R DOP1B

9.29e-05175685M6690
CoexpressionBAELDE_DIABETIC_NEPHROPATHY_DN

SCHIP1 KCND3 UGCG SSBP2 IRS1 F2R PDLIM5

1.38e-04437687M4665
CoexpressionGROSS_HIF1A_TARGETS_UP

DDR2 F2R

1.38e-047682M1306
CoexpressionGROSS_HIF1A_TARGETS_UP

DDR2 F2R

1.38e-047682MM548
CoexpressionTOMLINS_PROSTATE_CANCER_UP

ERG F2R PDLIM5

1.54e-0440683M19148
CoexpressionGSE19512_NAUTRAL_VS_INDUCED_TREG_UP

PRUNE2 SCHIP1 ERG CCR9 CMKLR1

1.62e-04197685M8361
CoexpressionGSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP

NHSL2 DDR2 PITX1 ZBTB7B NOTCH1

1.70e-04199685M8538
CoexpressionGSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP

AVPR1A CCR9 HECTD4 SSBP2 F2R

1.74e-04200685M3236
CoexpressionGSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP

NAT2 SCHIP1 DDR2 SEC24B SSBP3

1.74e-04200685M4056
CoexpressionGSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN

PRUNE2 SSBP2 IRS1 CMKLR1 MAP3K7

1.74e-04200685M7240
CoexpressionGSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP

NHSL2 DDR2 SLC4A4 NOTCH1 VDR

1.74e-04200685M7283
CoexpressionGSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP

NHSL2 DDR2 PITX1 ELF3 MAP3K7

1.74e-04200685M7279
CoexpressionGSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP

PTPN13 KCND3 ANKRD17 SSBP2 IRS1

1.74e-04200685M8690
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

TET2 PTPN13 SSBP2 IQCJ-SCHIP1 PDLIM5

2.28e-04212685M39221
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ARID1B PTPN13 ANKRD17 SSBP2 CADPS2 NFAT5

4.88e-07189696830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 ABCA13 PITX1 ELF3 SLC4A4 NOTCH1

6.41e-0719869619d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 BMX NAPEPLD ABCA13 UGCG

5.63e-06164695382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

SCHIP1 ERG LRCH2 CCR9 IQCJ-SCHIP1

5.80e-061656957b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

NAT2 GAD1 POU3F4 IRS1 F2R

6.52e-061696951d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NAT2 GAD1 POU3F4 IRS1 F2R

6.52e-0616969558098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARID1B PTPN13 POU3F4 CADPS2 NFAT5

6.71e-06170695928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRCH2 DDR2 SLIT3 HECTD4 SLC4A4

6.71e-061706955570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

BMX ERG LRCH2 DDR2 PLCG1

7.31e-06173695a81992965137195d20fc498f750975303961a828
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BMX MANSC1 ERG F2R PDLIM5

7.31e-061736953a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D32 ERG CRTC1 SSBP3 NOTCH1

7.51e-061746950fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D32 ERG CRTC1 SSBP3 NOTCH1

7.51e-06174695b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPN13 IQCJ-SCHIP1 CRYBG3 SLC4A4 CADPS2

8.85e-061806955e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERG DDR2 IRS1 SLC4A4 F2R

9.10e-06181695d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

9.59e-061836951645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCND3 DDR2 SLIT3 BEND2 ADGRG4

9.85e-06184695e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

9.85e-0618469534e316ad8e7b8667cd8ad61397281802a252744f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPN13 ABCA13 ELF3 SLC4A4 CADPS2

1.04e-05186695acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

PTPN13 KCND3 ABCA13 SLC4A4 CADPS2

1.09e-05188695ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 ERG IRS1 SLC4A4 CDH12

1.12e-05189695b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 ABCG1 NAPEPLD ABCA13 NFAT5

1.12e-05189695904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PRUNE2 BMX ERG ABCA13 UGCG

1.12e-051896953b35022c0619df6db234613aa53a076899ca9562
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRUNE2 BMX ERG ABCA13 UGCG

1.12e-05189695358ff514f1c8aa46067208ddf1b68396d789c130
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BMX ERG ABCA13 UGCG DOP1B

1.15e-05190695896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GAD1 NAPEPLD KCND3 ASCL1

1.18e-05191695501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GAD1 NAPEPLD KCND3 ASCL1

1.18e-051916958e06cc61eaff1796c2ce014074029408ba88d561
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRUNE2 GAD1 BMX ERG ABCA13

1.21e-05192695072281344d58e85c9a290750b488d0c101f75d54
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 ERG LRCH2 NHSL2 ADGRG4

1.37e-051976950dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC26A8 ABCA13 ELF3 DEPDC5 WNK3

1.40e-051986951fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DDR2 SLIT3 CRTC1 CRYBG3 F2R

1.44e-05199695615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN13 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

1.47e-052006959c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCellLPS_IL1RA-Endothelial-Endothelial-Vein|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ERG IQCJ-SCHIP1 CMKLR1 F2R PDLIM5

1.47e-05200695b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN13 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

1.47e-052006958821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

NHSL2 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

1.47e-052006950f23e72649a274043bf23e0952a9b5707c516acf
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN13 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

1.47e-0520069596b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN13 SLIT3 IQCJ-SCHIP1 SLC4A4 CDH12

1.47e-05200695ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCellsevere-unassigned|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ABCA13 DDR2 UGCG TP73

4.68e-05128694bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 TATDN2 DEPDC5 BEND2

6.28e-05138694a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellremission-multiplets|World / disease stage, cell group and cell class

TBC1D32 ERG ABCA13 UGCG

7.01e-05142694286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCellremission-multiplets|remission / disease stage, cell group and cell class

TBC1D32 ERG ABCA13 UGCG

8.45e-05149694e9974260a5f2999b363f306cae005698c912893a
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PITX1 ADGRG4 VDR

8.55e-05556930b62b4f438a493a30bddb99e1eadd20c92704ee9
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PITX1 ADGRG4 VDR

8.55e-0555693fa556ea954ea868a4b23e410f3b27d69e04794ee
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

9.36e-05153694e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GAD1 AVPR1A KCND3 BEND2

1.06e-04158694944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMX ERG CMKLR1 NOTCH1

1.28e-041666947a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAT2 PTPN13 ELF3 CADPS2

1.28e-04166694c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMX ERG CMKLR1 NOTCH1

1.28e-04166694bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT3 PITX1 F2R NSMAF

1.31e-04167694b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

PRUNE2 ERG SLIT3 IQCJ-SCHIP1

1.31e-04167694c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

TBC1D32 PLCG1 CMKLR1 TP73

1.37e-041696946abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A8 ABCA13 UGCG DOP1B

1.40e-04170694cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

BMX MANSC1 ERG F2R

1.44e-041716941597459c971d6befa991d59dc66b41b6a522f797
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

PRUNE2 ABCG1 NHSL2 SLIT3

1.47e-0417269436a96714a0eb6ac438648135336c9791881ddadb
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN13 LRCH2 DDR2 CRYBG3

1.54e-04174694f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NAPEPLD ASCL1 IQCJ-SCHIP1 CADPS2

1.54e-04174694b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD1 ERG NHSL2 NOTCH1

1.57e-0417569443be63976da5ad0764d24d90919a77ce46068f52
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERG DDR2 HECTD4 MAP3K7

1.57e-041756941d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERG LRCH2 SLIT3 SSBP3

1.57e-04175694316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERG DDR2 HECTD4 MAP3K7

1.57e-04175694427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERG LRCH2 SLIT3 SSBP3

1.57e-04175694a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

AVPR1A DDR2 SLIT3 BEND2

1.60e-041766942015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AVPR1A CDH12 WNK3 DOP1B

1.60e-041766946c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 SLIT3 ELF3 SSBP2

1.64e-04177694b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 SLIT3 CRYBG3 CADPS2

1.64e-041776944c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 SSBP2 F2R NOTCH1

1.64e-04177694ac0cf03e2a1baf84db3ae245d59bbc6ae52c13be
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 SLIT3 IQCJ-SCHIP1 CDH12

1.68e-041786945d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DDR2 SLIT3 SSBP2 PDLIM5

1.68e-0417869478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRUNE2 GAD1 MANSC1 DDR2

1.71e-04179694381ac15d59f31bc613828bdcfbc9192b106b4d18
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ERG DDR2 SLIT3 SSBP3

1.71e-04179694111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.71e-04179694fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 BMX MANSC1 ERG

1.71e-041796948c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 ASCL1 DDR2 PDLIM5

1.71e-041796940b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRUNE2 TET2 UGCG CRYBG3

1.71e-0417969414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AVPR1A IRS1 CDH12 DOP1B

1.75e-04180694cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLIT3 CRYBG3 SLC4A4 CADPS2

1.75e-04180694b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 SLIT3 CRYBG3 CADPS2

1.79e-0418169408f44323bf71b6004a921bbc969c954c75feeb66
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 AVPR1A DDR2 POU3F4

1.79e-041816949842537f9a607d8557c43790008d175edab1f32c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 ASCL1 DDR2 CMKLR1

1.79e-0418169403a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellfacs-Spleen-nan-3m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 SSBP2 PLCG1 NOTCH1

1.79e-04181694be7c7db6b99603759593e6f79cdcaa4bbf234cb7
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX MANSC1 ERG NHSL2

1.79e-041816940ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCG1 LRCH2 AVPR1A ASCL1

1.82e-04182694398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

UGCG CMKLR1 CRYBG3 VDR

1.82e-041826947b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.82e-0418269417ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

ABCG1 ERG NHSL2 CMKLR1

1.86e-041836943c4153479fc4ab2d073d92cee120480015555914
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN13 NAPEPLD KCND3 IQCJ-SCHIP1

1.86e-041836943c516fe5083f02bad1f464ed284010b4131a833c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPN13 ELF3 SLC4A4 CADPS2

1.86e-041836946847c1252d6bb105524f812658112517fd351eab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN13 NAPEPLD KCND3 IQCJ-SCHIP1

1.86e-041836949c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERG AVPR1A IRS1 CDH12

1.86e-04183694e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRCH2 DDR2 IRS1 SLC4A4

1.86e-0418369412daaea821e49bc94a01e2496331e92a80d27339
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.86e-04183694e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMX UGCG F2R NOTCH1

1.86e-04183694b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SP2 UBAP2 SEC24B CRTC1

1.90e-041846949cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCHIP1 BMX ERG F2R

1.90e-0418469416ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.90e-04184694d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|368C / Donor, Lineage, Cell class and subclass (all cells)

SP2 SEC24B CRTC1 ATG4D

1.90e-04184694d48807f9da48bdd015a54c606d2e2a311f181396
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.90e-04184694ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SCHIP1 ERG UGCG F2R

1.94e-04185694808d5e880069aff8866cd2c733b9fe568a37701f
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

PTPN13 ELF3 SLC4A4 CADPS2

1.94e-04185694cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellmild-Myeloid-Immature_Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BMX ERG ABCA13 UGCG

1.94e-04185694d747bc91fc276f12a5572ab0223fc71f829a5110
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 ELF3 SLC4A4 CADPS2

1.98e-04186694e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
DiseaseLarge cell carcinoma of lung

BMX DDR2 WNK3

5.29e-0532673C0345958
DiseaseSquamous cell carcinoma of lung

DDR2 NOTCH1 WNK3

5.29e-0532673C0149782
Diseasewaist circumference

TBC1D32 SLIT3 HECTD4 IQCJ-SCHIP1 CADPS2 NFAT5 CDH12

5.36e-05429677EFO_0004342
DiseaseProstatic Neoplasms

TET2 NAT2 ERG SSBP2 IRS1 MAP3K7 CDH12 VDR

7.61e-05616678C0033578
DiseaseMalignant neoplasm of prostate

TET2 NAT2 ERG SSBP2 IRS1 MAP3K7 CDH12 VDR

7.61e-05616678C0376358
Diseasebody weight

TET2 KCND3 SLIT3 HECTD4 CRTC1 SSBP2 IRS1 SSBP3 CADPS2 MAP3K7 NIPBL

1.18e-0412616711EFO_0004338
DiseaseChildhood Acute Lymphoblastic Leukemia

NAT2 ERG NOTCH1

2.28e-0452673C0023452
Diseaselung non-small cell carcinoma (is_implicated_in)

TET2 ARID1B PLCG1 TP73

2.87e-04139674DOID:3908 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

ARID1B DEPDC5 NIPBL NOTCH1 TP73

3.63e-04268675DOID:162 (implicated_via_orthology)
Diseaseoral squamous cell carcinoma (is_marker_for)

TET2 PTPN13 PLCG1

4.03e-0463673DOID:0050866 (is_marker_for)
DiseaseCoronary Arteriosclerosis

NAT2 HECTD4 IRS1

4.42e-0465673C0010054
DiseaseCoronary Artery Disease

NAT2 HECTD4 IRS1

4.42e-0465673C1956346
DiseaseP wave duration

KCND3 SSBP3

5.23e-0415672EFO_0005094
Diseaseskin pigmentation

CRTC1 CADPS2 MAP3K7

5.27e-0469673EFO_0003784
DiseaseBipolar Disorder

GAD1 ABCA13 SSBP2 PLCG1 PDLIM5 VDR

7.50e-04477676C0005586
Diseasehepatocellular carcinoma (is_implicated_in)

TET2 PTPN13 PLCG1 VDR

7.77e-04181674DOID:684 (is_implicated_in)
DiseaseIGF-1 measurement

AVPR1A SLIT3 PITX1 SLC4A4 NSMAF DOP1B

8.44e-04488676EFO_0004627
DiseasePseudopelade

MBTPS2 VDR

8.47e-0419672C0086873
DiseaseSchizophrenia

GAD1 SLC26A8 AVPR1A ABCA13 SLIT3 CADPS2 PDLIM5 WNK3

8.54e-04883678C0036341
DiseaseLiver carcinoma

NAT2 ARID1B MBTPS2 PITX1 DEPDC5 IRS1

1.03e-03507676C2239176
Diseaselung squamous cell carcinoma (is_implicated_in)

PTPN13 TP73

1.36e-0324672DOID:3907 (is_implicated_in)
Diseaseblood tin measurement

NAT2 SLIT3

1.47e-0325672EFO_0021530
Diseaseatopic dermatitis (is_implicated_in)

NAT2 VDR

1.59e-0326672DOID:3310 (is_implicated_in)
Diseasecerebellum cortex volume change measurement, age at assessment

ABCG1 CRTC1

1.59e-0326672EFO_0008007, EFO_0021497
Diseaseprostate carcinoma, breast carcinoma, ovarian carcinoma

TET2 ZBTB7B

1.72e-0327672EFO_0000305, EFO_0001075, EFO_0001663
Diseaseindole-3-propionate measurement

KCND3 SLIT3

1.72e-0327672EFO_0010501
DiseaseSezary Syndrome

TET2 PLCG1

1.72e-0327672C0036920
Diseaselevel of Sphingomyelin (d42:2) in blood serum

ANKRD17 SLC4A4

1.98e-0329672OBA_2045183
Diseasehematocrit

ARID1B UBAP2 ERG HECTD4 ANKRD17 CRTC1 ZBTB7B NFAT5

2.01e-031011678EFO_0004348
Diseaselevel of Sphingomyelin (d38:1) in blood serum

ANKRD17 SLC4A4

2.12e-0330672OBA_2045180
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

TET2 CCDC195 ARID1B IQCJ-SCHIP1 CADPS2 MAP3K7 NFAT5

2.24e-03801677EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseAdult T-Cell Lymphoma/Leukemia

PLCG1 TP73

2.26e-0331672C0023493

Protein segments in the cluster

PeptideGeneStartEntry
ITSSDMMDSSSFSNL

VDR

191

P11473
TPESNNSVYTSFMKS

PRKAG1

21

P54619
SSSSSYPEEVSMIVN

CRYBG3

1061

Q68DQ2
GTAMNASSYSAEMTE

ABCG1

11

P45844
KMTSAAHSENYSPAS

TBC1D32

481

Q96NH3
ESSMATSTPIYQMSS

ADGRG4

1501

Q8IZF6
KMDAPSSSTTLAQYD

BMX

181

P51813
SSSSDYGQTSKMSPR

ERG

36

P11308
SMSPSILSYMNQSKD

ABCA13

2616

Q86UQ4
SAMYSSEDSTLASVP

ELF3

16

P78545
SSPYSQPMNNSSSLM

ARID1B

1046

Q8NFD5
SSSLMNTQAPPYSMA

ARID1B

1056

Q8NFD5
PYSMAPAMVNSSAAS

ARID1B

1066

Q8NFD5
SQSTPESMLSGKSSY

ANKRD17

2276

O75179
KSTMDNPTTTQYASL

DYNLRB1

31

Q9NP97
AESSSVAMTPTYMDS

DEPDC5

1071

O75140
QANYDPLSDSDSMTS

ELOA2

471

Q8IYF1
MESSMQNYPSTRSPS

KCND3

521

Q9UK17
HSSLAASALSQMMSY

NOTCH1

2351

P46531
SDAAMYNNSEALPTS

DDR2

366

Q16832
AASAMVSSSAPSVYS

DOP1B

1881

Q9Y3R5
SSKNSTETANYPTLM

BEND2

311

Q8NDZ0
LPMDMSSYSKNSSSL

CCDC195

171

A0A1B0GUA6
TSTANTNMFTYEIAP

GAD1

206

Q99259
STDTNGSDNSIPMAY

MAP3K7

486

O43318
YKLSQNSMHSSPASS

NIPBL

126

Q6KC79
YNPTALSMSNVESST

MANSC1

336

Q9H8J5
SPAVSKVTSTNNMAY

PDLIM5

111

Q96HC4
NAETASVSDMGSMYT

HECTD4

3136

Q9Y4D8
DYMNMSPVGDSNTSS

IRS1

731

P35568
MEDSPSNFSNMSTSS

NFAT5

176

O94916
MATAASNPYSILSST

POU3F4

1

P49335
SSDPSSYNSSGQLMA

F2R

391

P25116
TMDQMSSRAASASPY

TP73

71

O15350
SYATDNEKMTSTPET

UPF3B

166

Q9BZI7
TDAQSITYNGSMDSP

FAM189B

261

P81408
LNSMAGSPVSSYSSD

ASCL1

201

P50553
MENAISSSSLYSPGS

CRTC1

511

Q6UUV9
SEAPMVNTVSSAYSE

C19orf44

456

Q9H6X5
PNMADDYGSESTSSM

CCR9

11

P51686
MPSLYESTNGSATSE

CADPS2

996

Q86UW7
AMSTQVAMQNSGSYS

UGCG

251

Q16739
TLAQMMADSPSSYSS

MBTPS2

101

O43462
DFESMNTYLQTSPTS

NAT2

201

P11245
KSLSQTSSYNASMAD

NSMAF

581

Q92636
IEDSSYPVQSSTNTM

CDH12

571

P55289
SPAMYSASSSVASQG

SEC24B

161

O95487
ANMSTQSPVSSEEYD

LRCH2

586

Q5VUJ6
QSYQPQSESASSSSM

PTPN13

1736

Q12923
FFNSMSPLSSQSMFS

PITX1

201

P78337
NPFQSESYSPSMTMS

SSBP2

346

P81877
DSTNSSDNIYTMINP

SSBP3

286

Q9BWW4
MSDYSPNSTGSVQNT

TATDN2

416

Q93075
VGESSQSSYDDPSMM

PRUNE2

1071

Q8WUY3
AFTYMTPSATSQSNQ

NHSL2

396

Q5HYW2
PMSKQSSSYSDRDTT

SCHIP1

331

P0DPB3
MYHPSMASTQSQTQT

SLC26A8

931

Q96RN1
SPMSKQSSSYSDRDT

IQCJ-SCHIP1

406

B3KU38
SYPSHRSFTKMSSMN

CMKLR1

346

Q99788
MNSVSPAAAQYRSSS

ATG4D

1

Q86TL0
SISMLTNYTFSNMSH

SLIT3

786

O75094
NSASPVAMSSSYDQS

UBAP2

606

Q5T6F2
AYTATLTTSSANMPA

ZBTB7B

106

O15156
SNYTAPSATMSSFQG

RNF34

181

Q969K3
TSMAATAAVSPSDYL

SP2

6

Q02086
PTSMMYSENDISNSI

PLCG1

476

P19174
TFYSNNRSPTNSTGM

AVPR1A

386

P37288
PTMSSTDMYHNTTFD

SLC4A4

651

Q9Y6R1
SSQAAGSYLNSSNPM

TET2

1601

Q6N021
SDSEAMMNNPGYESS

ZBTB34

341

Q8NCN2
TSSQPSVAYSSNQTM

WNK3

581

Q9BYP7
SNQSLMTSSQYPKEA

NAPEPLD

6

Q6IQ20