Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	NAD+-protein poly-ADP-ribosyltransferase activity	TNKS PARP9 SIRT6 TNKS2	7.27e-06	28	90	4	GO:0003950
GeneOntologyMolecularFunction	NAD+-protein ADP-ribosyltransferase activity	TNKS PARP9 SIRT6 TNKS2	9.67e-06	30	90	4	GO:1990404
GeneOntologyMolecularFunction	pentosyltransferase activity	TNKS PARP9 SIRT6 TNKS2	1.18e-04	56	90	4	GO:0016763
GeneOntologyBiologicalProcess	protein poly-ADP-ribosylation	TNKS PARP9 TNKS2	1.25e-05	11	89	3	GO:0070212
GeneOntologyBiologicalProcess	mitotic sister chromatid cohesion, telomeric	ATRX TNKS	1.84e-05	2	89	2	GO:0099404
GeneOntologyBiologicalProcess	maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	1.84e-05	2	89	2	GO:0099403
GeneOntologyBiologicalProcess	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	1.84e-05	2	89	2	GO:1904908
GeneOntologyBiologicalProcess	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	1.84e-05	2	89	2	GO:1904907
GeneOntologyBiologicalProcess	protein localization to chromosome	ATRX TONSL TNKS BRD3 SIRT6 TNKS2	3.21e-05	140	89	6	GO:0034502
GeneOntologyBiologicalProcess	negative regulation of maintenance of sister chromatid cohesion	ATRX TNKS	5.51e-05	3	89	2	GO:0034092
GeneOntologyBiologicalProcess	negative regulation of maintenance of mitotic sister chromatid cohesion	ATRX TNKS	5.51e-05	3	89	2	GO:0034183
GeneOntologyBiologicalProcess	interleukin-3 production	SLC11A1 SYK	1.10e-04	4	89	2	GO:0032632
GeneOntologyBiologicalProcess	peptidyl-threonine phosphorylation	CDC42BPA TRPC5 TNKS APP CDC42BPB	1.41e-04	115	89	5	GO:0018107
GeneOntologyBiologicalProcess	peptidyl-threonine modification	CDC42BPA TRPC5 TNKS APP CDC42BPB	2.08e-04	125	89	5	GO:0018210
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance	ATRX TNKS SIRT6 TNKS2	2.66e-04	72	89	4	GO:0032206
GeneOntologyBiologicalProcess	negative regulation of sister chromatid cohesion	ATRX TNKS	2.73e-04	6	89	2	GO:0045875
GeneOntologyCellularComponent	chromosome, subtelomeric region	ATRX SIRT6	2.00e-05	2	94	2	GO:0099115
GeneOntologyCellularComponent	FACT complex	TONSL SUPT16H	1.19e-04	4	94	2	GO:0035101
Domain	KELK	CDC42BPA CDC42BPB	2.40e-05	2	92	2	IPR031597
Domain	KELK	CDC42BPA CDC42BPB	2.40e-05	2	92	2	PF15796
Domain	NPIP	NPIPB13 NPIPB3 NPIPB5	4.05e-05	14	92	3	IPR009443
Domain	Poly(ADP-ribose)pol_cat_dom	TNKS PARP9 TNKS2	7.48e-05	17	92	3	IPR012317
Domain	PARP_CATALYTIC	TNKS PARP9 TNKS2	7.48e-05	17	92	3	PS51059
Domain	PARP	TNKS PARP9 TNKS2	7.48e-05	17	92	3	PF00644
Domain	-	TNKS PARP9 TNKS2	7.48e-05	17	92	3	3.90.228.10
Domain	Quinoprotein_ADH-like_supfam	CFAP251 WDR87 EML1 CFAP57	1.34e-04	53	92	4	IPR011047
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	1.43e-04	4	92	2	IPR014930
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	1.43e-04	4	92	2	PD011252
Domain	DMPK_coil	CDC42BPA CDC42BPB	1.43e-04	4	92	2	PF08826
Domain	C1_1	CDC42BPA PDZD8 UNC13C CDC42BPB	1.78e-04	57	92	4	PF00130
Domain	WGR_domain	TNKS PARP9 TNKS2	2.17e-04	24	92	3	IPR008893
Domain	ZF_DAG_PE_1	CDC42BPA PDZD8 UNC13C CDC42BPB	2.79e-04	64	92	4	PS00479
Domain	ZF_DAG_PE_2	CDC42BPA PDZD8 UNC13C CDC42BPB	2.79e-04	64	92	4	PS50081
Domain	C1	CDC42BPA PDZD8 UNC13C CDC42BPB	2.97e-04	65	92	4	SM00109
Domain	PE/DAG-bd	CDC42BPA PDZD8 UNC13C CDC42BPB	3.15e-04	66	92	4	IPR002219
Domain	ZINC_FINGER_C2H2_2	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	4.12e-04	775	92	12	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	4.22e-04	777	92	12	PS00028
Domain	Znf_C2H2-like	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	5.24e-04	796	92	12	IPR015880
Domain	Znf_C2H2	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	5.78e-04	805	92	12	IPR007087
Domain	zf-C2H2	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	5.93e-04	693	92	11	PF00096
Domain	ZnF_C2H2	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	5.98e-04	808	92	12	SM00355
Domain	PH-BEACH_dom	NBEA NSMAF	6.59e-04	8	92	2	IPR023362
Domain	-	NBEA NSMAF	6.59e-04	8	92	2	2.30.29.40
Domain	PH_BEACH	NBEA NSMAF	6.59e-04	8	92	2	PS51783
Domain	Ank_2	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	6.79e-04	215	92	6	PF12796
Domain	BEACH_dom	NBEA NSMAF	8.45e-04	9	92	2	IPR000409
Domain	BEACH	NBEA NSMAF	8.45e-04	9	92	2	PS50197
Domain	Beach	NBEA NSMAF	8.45e-04	9	92	2	PF02138
Domain	-	NBEA NSMAF	8.45e-04	9	92	2	1.10.1540.10
Domain	Beach	NBEA NSMAF	8.45e-04	9	92	2	SM01026
Domain	Ank	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	9.22e-04	228	92	6	PF00023
Domain	-	CFAP251 WDR87 NBEA EML1 CFAP57 PLXNA1 NSMAF	1.29e-03	333	92	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	CFAP251 WDR87 NBEA EML1 CFAP57 PLXNA1 NSMAF	1.33e-03	335	92	7	IPR015943
Domain	-	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.42e-03	248	92	6	1.25.40.20
Domain	ANK	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.51e-03	251	92	6	SM00248
Domain	ANK_REPEAT	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.57e-03	253	92	6	PS50088
Domain	Ankyrin_rpt-contain_dom	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.60e-03	254	92	6	IPR020683
Domain	ANK_REP_REGION	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.60e-03	254	92	6	PS50297
Domain	WD40	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	1.77e-03	259	92	6	PF00400
Domain	-	ZNF655 ZNF587 ZFP91 ZSCAN26 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	1.86e-03	679	92	10	3.30.160.60
Domain	Ankyrin_rpt	TRPC5 SOWAHD TONSL ASB1 TNKS TNKS2	1.87e-03	262	92	6	IPR002110
Domain	WD40	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	2.10e-03	268	92	6	SM00320
Domain	Znf_UBP	USP44 USP22	2.10e-03	14	92	2	IPR001607
Domain	zf-UBP	USP44 USP22	2.10e-03	14	92	2	PF02148
Domain	ZF_UBP	USP44 USP22	2.10e-03	14	92	2	PS50271
Domain	CNH	CDC42BPA CDC42BPB	2.10e-03	14	92	2	SM00036
Domain	Znf_C2H2/integrase_DNA-bd	ZNF655 ZNF587 ZFP91 ZSCAN26 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	2.18e-03	694	92	10	IPR013087
Domain	WD40_repeat	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	2.26e-03	272	92	6	IPR001680
Domain	TPR_8	IFIT1B TONSL IFIT5	2.27e-03	53	92	3	PF13181
Domain	CNH	CDC42BPA CDC42BPB	2.42e-03	15	92	2	PF00780
Domain	CNH	CDC42BPA CDC42BPB	2.42e-03	15	92	2	PS50219
Domain	CNH_dom	CDC42BPA CDC42BPB	2.42e-03	15	92	2	IPR001180
Domain	WD_REPEATS_1	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	2.52e-03	278	92	6	PS00678
Domain	WD_REPEATS_2	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	2.57e-03	279	92	6	PS50082
Domain	WD_REPEATS_REGION	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	2.57e-03	279	92	6	PS50294
Domain	PBD	CDC42BPA CDC42BPB	2.75e-03	16	92	2	SM00285
Domain	WD40_repeat_dom	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	3.49e-03	297	92	6	IPR017986
Domain	TPR	IFIT1B TONSL IFIT5 GPSM1	3.80e-03	129	92	4	SM00028
Domain	TPR_repeat	IFIT1B TONSL IFIT5 GPSM1	4.23e-03	133	92	4	IPR019734
Domain	CRIB	CDC42BPA CDC42BPB	4.30e-03	20	92	2	PS50108
Domain	CRIB_dom	CDC42BPA CDC42BPB	4.74e-03	21	92	2	IPR000095
Pubmed	Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.	SYK TNKS TNKS2	7.08e-07	7	96	3	22153076
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	GMPS AARS1 ADNP2 TNKS BRD3 ZNF217 DOT1L TNKS2 APP	1.66e-06	398	96	9	35016035
Pubmed	Tankyrase is necessary for canonical Wnt signaling during kidney development.	TNKS TNKS2	7.54e-06	2	96	2	20549720
Pubmed	Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.	TNKS TNKS2	7.54e-06	2	96	2	27494558
Pubmed	CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.	NFATC1 SYK	7.54e-06	2	96	2	31921172
Pubmed	Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.	CDC42BPA CDC42BPB	7.54e-06	2	96	2	10198171
Pubmed	Regulation of tankyrase activity by a catalytic domain dimer interface.	TNKS TNKS2	7.54e-06	2	96	2	30055800
Pubmed	Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.	CDC42BPA CDC42BPB	7.54e-06	2	96	2	18263588
Pubmed	Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.	TNKS TNKS2	7.54e-06	2	96	2	24291818
Pubmed	Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.	TNKS TNKS2	7.54e-06	2	96	2	18612384
Pubmed	Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy.	TNKS TNKS2	7.54e-06	2	96	2	28723574
Pubmed	Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.	TNKS TNKS2	7.54e-06	2	96	2	18026951
Pubmed	Structural insights into SAM domain-mediated tankyrase oligomerization.	TNKS TNKS2	7.54e-06	2	96	2	27328430
Pubmed	Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.	TNKS TNKS2	7.54e-06	2	96	2	24116873
Pubmed	Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1.	TNKS TNKS2	7.54e-06	2	96	2	15795250
Pubmed	Amyloid cross-sequence interaction between Aβ(1-40) and αA(66-80) in relation to the pathogenesis of cataract.	CRYAA APP	7.54e-06	2	96	2	33626371
Pubmed	Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.	TNKS TNKS2	7.54e-06	2	96	2	29263426
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AARS1 NEUROD2 ATRX ZNF655 ZNF451 NISCH ADNP2 PDZD8 IFIT5 NBEA TNKS TNKS2 APP CDC42BPB	1.17e-05	1285	96	14	35914814
Pubmed	Genomic analysis of mouse retinal development.	STK16 CFAP251 USP22 NFATC1 TONSL SUPT16H ADNP2 PDZD8 ARRDC3 EML1 TNKS2 CEP164	2.16e-05	1006	96	12	15226823
Pubmed	Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation.	TNKS TNKS2	2.26e-05	3	96	2	32442396
Pubmed	Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells.	ATRX TNKS	2.26e-05	3	96	2	26373281
Pubmed	Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.	TNKS TNKS2	2.26e-05	3	96	2	11739745
Pubmed	The ancient regulatory-protein family of WD-repeat proteins.	CFAP251 CFAP57	2.26e-05	3	96	2	8090199
Pubmed	Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.	TNKS TNKS2	2.26e-05	3	96	2	25939383
Pubmed	Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.	TNKS TNKS2	2.26e-05	3	96	2	33923443
Pubmed	TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.	TNKS TNKS2	2.26e-05	3	96	2	11454873
Pubmed	Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.	TNKS TNKS2	2.26e-05	3	96	2	21251231
Pubmed	Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.	TNKS TNKS2	2.26e-05	3	96	2	26246473
Pubmed	Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.	TNKS TNKS2	2.26e-05	3	96	2	33361107
Pubmed	Neuregulin-1 exerts protective effects against neurotoxicities induced by C-terminal fragments of APP via ErbB4 receptor.	ERBB4 APP	2.26e-05	3	96	2	22739235
Pubmed	Divergent origins and concerted expansion of two segmental duplications on chromosome 16.	NPIPB3 NPIPB5	2.26e-05	3	96	2	11948212
Pubmed	Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.	TNKS TNKS2	2.26e-05	3	96	2	27441654
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GMPS PTPRB CDC42BPA SUPT16H PDZD8 NBEA CPD BRD3 APP CDC42BPB ADCY9 HDLBP	3.24e-05	1049	96	12	27880917
Pubmed	Functional proteomics mapping of a human signaling pathway.	SEC24D PRSS8 EVC2 ATRX EXPH5 ZNF587 ZNF451 TNKS2 HDLBP	3.88e-05	591	96	9	15231748
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	AARS1 FAT1 SUPT16H IFIT5 PARP9 ZNF217 CDC42BPB	3.91e-05	332	96	7	37433992
Pubmed	PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.	TNKS TNKS2	4.51e-05	4	96	2	38272024
Pubmed	Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells.	SYK KIR2DS2	4.51e-05	4	96	2	9490415
Pubmed	Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.	TNKS TNKS2	4.51e-05	4	96	2	30260955
Pubmed	Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction.	SYK DOT1L	4.51e-05	4	96	2	34635982
Pubmed	Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression.	TNKS TNKS2	4.51e-05	4	96	2	36383218
Pubmed	A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.	CDC42BPA CDC42BPB	4.51e-05	4	96	2	18854160
Pubmed	The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182).	TNKS TNKS2	4.51e-05	4	96	2	11854288
Pubmed	WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases.	CFAP251 CFAP57	4.51e-05	4	96	2	11814058
Pubmed	Systemic lupus erythematosus: association with KIR and SLC11A1 polymorphisms, ethnic predisposition and influence in clinical manifestations at onset revealed by ancestry genetic markers in an urban Brazilian population.	SLC11A1 KIR2DS2	4.51e-05	4	96	2	21233146
Pubmed	E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.	TNKS TNKS2	4.51e-05	4	96	2	26513298
Pubmed	Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.	CDC42BPA CDC42BPB	4.51e-05	4	96	2	9418861
Pubmed	Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14.	TNKS TNKS2	4.51e-05	4	96	2	11278563
Pubmed	The WD repeat: a common architecture for diverse functions.	CFAP251 CFAP57	4.51e-05	4	96	2	10322433
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ATRX POLA1 ZNF451 ZFP91 ZSCAN26 SUPT16H ADNP2 BRD3 DOT1L	4.83e-05	608	96	9	36089195
Pubmed	Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase).	TNKS TNKS2	7.50e-05	5	96	2	11802774
Pubmed	Tankyrase represses autoinflammation through the attenuation of TLR2 signaling.	TNKS TNKS2	7.50e-05	5	96	2	35362478
Pubmed	The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation.	TNKS TNKS2	7.50e-05	5	96	2	22473005
Pubmed	Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate.	SPTA1 SYK	7.50e-05	5	96	2	23533167
Pubmed	Diversity of WD-repeat proteins.	CFAP251 CFAP57	7.50e-05	5	96	2	18925368
Pubmed	Syk mediates IL-17-induced CCL20 expression by targeting Act1-dependent K63-linked ubiquitination of TRAF6.	TRAF3IP2 SYK	7.50e-05	5	96	2	25202827
Pubmed	Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.	TNKS TNKS2	1.12e-04	6	96	2	34128958
Pubmed	Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.	TNKS TNKS2	1.12e-04	6	96	2	19759537
Pubmed	Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.	TNKS TNKS2	1.12e-04	6	96	2	21799911
Pubmed	Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.	TNKS TNKS2	1.12e-04	6	96	2	26845027
Pubmed	Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles.	TNKS TNKS2	1.12e-04	6	96	2	10988299
Pubmed	The broad-spectrum antiviral functions of IFIT and IFITM proteins.	IFIT1B IFIT5	1.12e-04	6	96	2	23237964
Pubmed	Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.	CDC42BPA CDC42BPB	1.12e-04	6	96	2	25107909
Pubmed	ATRX proximal protein associations boast roles beyond histone deposition.	ATRX ZNF655 SUPT16H DOT1L	1.21e-04	91	96	4	34780483
Pubmed	RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.	TNKS TNKS2	1.57e-04	7	96	2	21478859
Pubmed	MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.	CDC42BPA CDC42BPB	1.57e-04	7	96	2	29162624
Pubmed	Two new behavioral QTLs, Emo4 and Reb1, map to mouse Chromosome 1: Congenic strains and candidate gene identification studies.	ERBB4 ASB1	1.57e-04	7	96	2	16465591
Pubmed	Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.	APP ABCD2	1.57e-04	7	96	2	16223892
Pubmed	TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.	SYK APP	1.57e-04	7	96	2	29518356
Pubmed	Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.	TNKS TNKS2	1.57e-04	7	96	2	25547115
Pubmed	Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.	TNKS TNKS2	1.57e-04	7	96	2	31554794
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	FAT1 CDC42BPA EXPH5 SIGLEC6 CPD CDC42BPB PLXNA1 ADCY9	1.84e-04	569	96	8	30639242
Pubmed	A "double adaptor" method for improved shotgun library construction.	CCDC88C ERBB4 ASB1 TNKS CPD BRD3 EML1 CALN1	1.95e-04	574	96	8	8619474
Pubmed	Osteoprotection by semaphorin 3A.	NFATC1 PLXNA1	2.09e-04	8	96	2	22522930
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MPP3 CCDC88C FAT1 CDC42BPA NFATC1 NISCH PDZD8 DOT1L CDC42BPB PLXNA1 ADCY9	2.38e-04	1105	96	11	35748872
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CDC42BPA NISCH CPD CDC42BPB HDLBP	2.50e-04	202	96	5	24639526
Pubmed	ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.	USP44 USP22	2.68e-04	9	96	2	29669287
Pubmed	Siglec-15 protein regulates formation of functional osteoclasts in concert with DNAX-activating protein of 12 kDa (DAP12).	NFATC1 SYK	2.68e-04	9	96	2	22451653
Pubmed	Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis.	TNKS TNKS2	2.68e-04	9	96	2	19766477
Pubmed	Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner.	TNKS TNKS2	2.68e-04	9	96	2	12080061
Pubmed	USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization.	SEC24D SIRT6 APP	3.03e-04	47	96	3	33903120
Pubmed	A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.	TONSL SUPT16H	3.34e-04	10	96	2	21055985
Pubmed	Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.	ERBB4 PLXNA1	4.08e-04	11	96	2	25315821
Pubmed	Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.	TNKS TNKS2	4.08e-04	11	96	2	20937264
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CAND2 CDC42BPA SUPT16H TNKS TNKS2 ZNF417 CDC42BPB	4.65e-04	497	96	7	23414517
Pubmed	An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation.	EML1 CDC42BPB	4.89e-04	12	96	2	11867214
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	GMPS AARS1 USP22 ATRX POLA1 ZNF451 ZFP91 SUPT16H BRD3 SIRT6	4.98e-04	1014	96	10	32416067
Pubmed	Sex-specific effect of insulin-dependent diabetes 4 on regulation of diabetes pathogenesis in the nonobese diabetic mouse.	SLC11A1 HDLBP	5.77e-04	13	96	2	15905556
Pubmed	PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.	CDC42BPA CDC42BPB	6.71e-04	14	96	2	18586681
Pubmed	A trans-eQTL network regulates osteoclast multinucleation and bone mass.	EML1 DOT1L	6.71e-04	14	96	2	32553114
Pubmed	Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.	TNKS TNKS2	6.71e-04	14	96	2	35733260
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CAND2 CDC42BPA ATRX ZNF451 NISCH SUPT16H PDZD8 CPD APP CDC42BPB ADCY9 HDLBP	8.08e-04	1487	96	12	33957083
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	TNKS TNKS2	8.82e-04	16	96	2	28619731
Pubmed	High-throughput RNAi screening reveals novel regulators of telomerase.	TNKS TNKS2	8.82e-04	16	96	2	21531765
Pubmed	Family-wide analysis of poly(ADP-ribose) polymerase activity.	TNKS TNKS2	8.82e-04	16	96	2	25043379
Pubmed	Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis.	SPTA1 HDLBP	9.98e-04	17	96	2	9250876
Pubmed	Large-scale concatenation cDNA sequencing.	CCDC88C ERBB4 ASB1 TNKS BRD3 EML1 CALN1	1.02e-03	568	96	7	9110174
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERBB4 FAT1 USP22 ZFP91 SUPT16H ADNP2 BRD3 APP ADCY9 ZNF829	1.03e-03	1116	96	10	31753913
Pubmed	A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease.	SPTA1 APP	1.12e-03	18	96	2	16049941
Pubmed	Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.	CRYAA APP	1.12e-03	18	96	2	1783381
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ATRX NFATC1 ZNF451 TONSL ZNF217 DOT1L HDLBP	1.24e-03	588	96	7	38580884
Cytoband	16p12.2	NPIPB4 NPIPB3 NPIPB5	6.54e-05	37	96	3	16p12.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF655 ZNF587 ZNF451 ZFP91 ZSCAN26 ADNP2 ZNF571 ZNF217 ZNF700 ZNF417 ZNF829 ZNF563	8.17e-06	718	65	12	28
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TNKS PARP9 TNKS2	2.91e-05	17	65	3	684
GeneFamily	WD repeat domain containing	CFAP251 WDR87 NBEA EML1 CFAP57 NSMAF	3.53e-04	262	65	6	362
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA NSMAF	4.51e-04	9	65	2	1230
GeneFamily	Ankyrin repeat domain containing	SOWAHD TONSL ASB1 TNKS TNKS2	1.77e-03	242	65	5	403
ToppCell	COVID-19_Mild-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CFAP251 EXPH5 OSBP2 CFAP57 ADCY9	6.97e-06	124	95	5	5ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRYAA SLC15A3 ABCD2 PLXNA1 ADCY9	2.32e-05	159	95	5	0c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCell	ASK428-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	FILIP1 FAT1 PTPRB SIGLEC6 NBEA	3.02e-05	168	95	5	c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88C CFAP251 NBEA CFAP57 KIAA2012	3.11e-05	169	95	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GMPS PTPRB PARP9 EML1 MAP3K6	3.38e-05	172	95	5	94093d356b0252b440deda4e1b0ac332b31513f6
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYAA DDX60 NISCH SYK ARRDC3	3.67e-05	175	95	5	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SUPT16H TNKS ARRDC3 HDLBP	3.77e-05	176	95	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	DDX60 NPIPB3 OSBP2 TNKS NPIPB5	3.77e-05	176	95	5	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C FILIP1 PTPRB ATRX TNKS	3.98e-05	178	95	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NARF DPY19L1 ASB1 ABCD2 PLXNA1	3.98e-05	178	95	5	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 ADNP2 EML1 KIAA2012 MAP3K6	4.09e-05	179	95	5	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CEP104 PTPRB SLC11A1 DPY19L1 ADCY9	4.09e-05	179	95	5	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DDX60 IFIT5 PARP9 ZNF217 ARRDC3	4.54e-05	183	95	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ERBB4 CFAP251 TEKT4 CFAP57	4.78e-05	185	95	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 NEUROD2 EXPH5 UNC13C CALN1	4.91e-05	186	95	5	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	severe_influenza-RBC\|World / disease group, cell group and cell class (v2)	NARF FAT1 SPTA1 IFIT1B OSBP2	5.03e-05	187	95	5	f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 NBEA TEKT4 CFAP57 KIAA2012	5.03e-05	187	95	5	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 NEUROD2 EXPH5 UNC13C CALN1	5.03e-05	187	95	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 NEUROD2 EXPH5 UNC13C CALN1	5.29e-05	189	95	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	DDX60 IFIT5 PARP9 ARRDC3 SLC15A3	5.56e-05	191	95	5	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MPP3 PRSS8 CDC42BPA NBEA GPSM1	5.70e-05	192	95	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MPP3 PRSS8 CDC42BPA NBEA GPSM1	5.70e-05	192	95	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	GMPS DPY19L1 UHMK1 PDZD8 PARP9	5.70e-05	192	95	5	4e689bca7a242f8482e25f273656e2caba8821c0
ToppCell	Influenza_Severe-RBC\|Influenza_Severe / Disease group and Cell class	NARF SPTA1 ZNF451 IFIT1B OSBP2	5.70e-05	192	95	5	f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPIPB4 NPIPB11 SPTA1 ZNF451 OSBP2	5.84e-05	193	95	5	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	severe_influenza-RBC\|severe_influenza / disease group, cell group and cell class (v2)	NARF SPTA1 ZNF451 IFIT1B OSBP2	5.84e-05	193	95	5	ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 NEUROD2 EXPH5 UNC13C CALN1	5.84e-05	193	95	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 ATRX NISCH NBEA TNKS2	6.14e-05	195	95	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 CFAP251 PTPRB EML1 APP	6.29e-05	196	95	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	MPP3 TRAF3IP2 FAT1 ZNF571 CFAP57	6.44e-05	197	95	5	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP44 MPP3 FILIP1 SEC24D FAT1	6.60e-05	198	95	5	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CDC42BPA ATRX EXPH5 PARP9 HDLBP	6.60e-05	198	95	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	NEUROD2 ATRX NBEA EML1 APP	6.75e-05	199	95	5	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 PLEKHS1 TEKT4 CFAP57 KIAA2012	6.92e-05	200	95	5	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 PLEKHS1 TEKT4 CFAP57 KIAA2012	6.92e-05	200	95	5	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA DPY19L1 ARRDC3 EML1 APP	6.92e-05	200	95	5	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERBB4 SPTA1 IFIT1B OSBP2	1.11e-04	116	95	4	c1a8d8068efb0e6b88f230df351094b69a4e56e2
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ERBB4 SPTA1 IFIT1B OSBP2	1.11e-04	116	95	4	3a11fde2b0a0dad26f6876a3ab3949edfb8b97e2
ToppCell	PBMC-Control-Hematopoietic-RBC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERBB4 SPTA1 IFIT1B OSBP2	1.11e-04	116	95	4	ca72dfb23c3335cb6bb0d1be5dc032e044eaff1a
ToppCell	Control-Hematopoietic_R\|Control / Disease group, lineage and cell class	ERBB4 SPTA1 IFIT1B OSBP2	1.15e-04	117	95	4	48c909e3e068d1da5d39f1cf23a321d5e1f31a74
ToppCell	Control-Hematopoietic_R-RBC\|Control / Disease group, lineage and cell class	ERBB4 SPTA1 IFIT1B OSBP2	1.15e-04	117	95	4	2f8fa933b76f40d2f07391b0f7394483e25bd642
ToppCell	PBMC-Control-Hematopoietic-RBC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB4 SPTA1 IFIT1B OSBP2	1.19e-04	118	95	4	e1fb21a8ec0f7b8b828d12e5dc8b470dbf3dc810
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB4 SPTA1 IFIT1B OSBP2	1.19e-04	118	95	4	25d35c13d51a347e305f3a3ce239800cf118848e
ToppCell	PBMC-Control-Hematopoietic-RBC-RBC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB4 SPTA1 IFIT1B OSBP2	1.19e-04	118	95	4	68a891a0597d206ad5f66c6e087126f020e972b5
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA CDC42BPB	4.75e-04	11	88	2	DOID:0060669 (implicated_via_orthology)
Disease	atrial fibrillation	FILIP1 ERBB4 CAND2 NFATC1 SOWAHD SYK	8.64e-04	371	88	6	EFO_0000275
Disease	mean platelet volume	MPP3 NARF CFAP251 NFATC1 POLA1 SPTA1 SYK BRD3 ZNF217 CDC42BPB	9.18e-04	1020	88	10	EFO_0004584
Disease	neck circumference	USP44 CALN1	1.45e-03	19	88	2	EFO_0011043
Disease	azoospermia (implicated_via_orthology)	CDC42BPA CDC42BPB	2.94e-03	27	88	2	DOID:14227 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGCLLEYVHEHKDNI	ERBB4	801	Q15303
EALELHDYHDIIKHP	BRD3	341	Q15059
EELLSGKINRHEHYF	CALR3	361	Q96L12
HDKGYTDQDLERILH	ABCD2	571	Q9UBJ2
RHDSGYEVHHQKLVF	APP	676	P05067
KALIRYGADVDVNHH	ASB1	161	Q9Y576
VYDKHHDAAHEIIET	DOT1L	26	Q8TEK3
EELKHILYHAFRDHL	CALN1	176	Q9BXU9
YFNHKDILIGHERDD	ARRDC3	81	Q96B67
TTEAYELHLKERHHI	ADNP2	886	Q6IQ32
RSYKDHLEVLDIHHT	CFAP251	776	Q8TBY9
EYLRKVINTLADHHH	NPIPB3	36	Q92617
YKDTLHLIGEHHDGV	KIR2DS2	66	P43631
IENNHILYLGRKEHD	PARP9	546	Q8IXQ6
EYLRKVINTLADHHH	NPIPB12	36	F8W0I5
GRNGEVHYYLKEHHE	FAT1	2111	Q14517
DIYGAVHDLRLHRVH	PTPRB	1931	P23467
EHGRALEYHKHDLLL	GPSM1	81	Q86YR5
AHGRKAHHYTIEREL	SYK	56	P43405
LRTEKEKQDVYHHEH	CFAP57	751	Q96MR6
YHHEHIEDLLDKQSR	CFAP57	761	Q96MR6
EELKALAERGIGYHH	DDX60	1251	Q8IY21
HQLKGEYEELHAHTK	CCDC88C	1266	Q9P219
YLHDNHIVHRDIKGD	MAP3K6	761	O95382
EPHHRKEHYLSSVQE	PLXNA1	151	Q9UIW2
IHFKYLKEGESDHHV	PDZD8	791	Q8NEN9
EVQPKSHHRAHYETE	NFATC1	431	O95644
VRKHQFDHGELVYHA	DPY19L1	441	Q2PZI1
KVGRDYDVHHLHRGL	KIAA2012	771	Q0VF49
THLIQKHERAGYLDE	EVC2	621	Q86UK5
RHGNITERHKKHYNE	EXPH5	251	Q8NEV8
EYLRKVINTLADHHH	NPIPB5	36	A8MRT5
SHHHFLYGLLEEDQK	SLC11A1	531	P49279
IHQLHYVHRDIKPDN	CDC42BPB	191	Q9Y5S2
EYLRKVINTLADHHH	NPIPB4	36	C9JG80
EDLEYHHLLDKAVHC	OSBP2	556	Q969R2
LDPTQFRVHHYHKDE	POLA1	1241	P09884
FRVHHYHKDEENDAL	POLA1	1246	P09884
EYLRKVINTLADHHH	NPIPB11	36	E5RHQ5
KDYIRHLHDSQHVAV	CPT1C	321	Q8TCG5
LQIHKEHIVGYHEHD	ATRX	2241	P46100
REKLIDHYLGHNSED	CEP104	166	O60308
RLENITDDHKHQIHY	IFIT5	366	Q13325
DLKDGHHHYEGAVVI	GMPS	16	P49915
LAETYAEIGHHRKAE	IFIT1B	346	Q5T764
KDGFHRLRQHHDEYE	CPD	1331	O75976
LHYHGDVEADLHRTK	ADCY9	1006	O60503
QLHEHYKIHKEAVTG	NSMAF	621	Q92636
VVLHVAYHEGREKRH	GJB7	91	Q6PEY0
HYAGHNDDVKCLAVH	EML1	266	O00423
IHGKHNERQDDHGYI	CRYAA	96	P02489
LNHVEDGLKDHYDIR	CAND2	1111	O75155
GVLEMERLHYIHHNE	SLC15A3	426	Q8IY34
EYLRKVINTLADHHH	NPIPB13	36	A6NJU9
DFIEHYAHLGLKGHR	PURG	121	Q9UJV8
LHHNKFLEHGEYKEN	MPP3	446	Q13368
VTHIEKRYGLHEHRD	RELL2	171	Q8NC24
HDGHFYALKRILCHE	STK16	41	O75716
HRRTVYELENEKHKH	FILIP1	176	Q7Z7B0
ESDIHLAEHHKQVLY	NBEA	421	Q8NFP9
EQELHYAVLHFHKVQ	SIGLEC6	421	O43699
CEELEDARYKLHHHL	TEKT4	296	Q8WW24
AKHGRHEELILVHDF	SOWAHD	156	A6NJG2
HHKEAYEVKLGAHQL	PRSS8	91	Q16651
HDRHADLRIHGYVDE	SIRT6	246	Q8N6T7
LGKHQHMHDRDDLYA	SUPT16H	751	Q9Y5B9
SVHQLHYVHRDIKPD	CDC42BPA	191	Q5VT25
HLDHIGRRLDHYEKP	SEC24D	401	O94855
LGQVEHRVHQKSYHV	CEP164	811	Q9UPV0
LDEDEHGLHTKYIHR	TRAF3IP2	486	O43734
YKDHHHRGSIEIDQN	PLEKHS1	56	Q5SXH7
HKIETLYRHCQDEHD	ZNF451	646	Q9Y4E5
LQIHARTHIGEKHYE	ZNF700	691	Q9H0M5
HARHLAGYEQQDAHE	USP22	251	Q9UPT9
ETRDIHDYIKHLGHM	UNC13C	301	Q8NB66
KHNDLDDVGKDVYHH	AARS1	81	P49588
KDHHGAVRHYEEELR	TONSL	366	Q96HA7
EYLLHHGADVHAKDK	TNKS	701	O95271
DTAYLHQHQKQHIGE	ZNF587	131	Q96SQ5
VKHRYSDFHDLHEKL	NISCH	46	Q9Y2I1
DTAYLHQHQKQHIGE	ZNF417	131	Q8TAU3
RHQQHKHEIDSYDDR	SPTA1	411	P02549
VNAIIHKGFDERHAY	TNKS2	1036	Q9H2K2
NHHRIHAGEKLYECE	ZNF829	341	Q3KNS6
HLAQHVRIHNEEKPY	ZSCAN26	436	Q16670
HIRVDSGHKPHEYQE	ZNF563	121	Q8TA94
LEHQRVHHEEKAYEY	ZNF655	346	Q8N720
YHLERHHKEKQTDVA	ZNF217	516	O75362
HRDDHSEELDPQKYH	TRPC5	271	Q9UL62
RHAKHHTDQRDYICE	ZFP91	361	Q96JP5
DYVEINIDHKFHRHL	HDLBP	436	Q00341
HLAKHEAIVYRHRQA	WDR87	2566	Q6ZQQ6
YLTQHEKIHGEKHYE	ZNF571	461	Q7Z3V5
LAFLHHEGYVHADLK	UHMK1	146	Q8TAS1
VLKSHQAHQRHLYDE	SPATA6	386	Q9NWH7
HVACGRYIEEHALKH	USP44	46	Q9H0E7
DGHLAHIFRHAAKEL	NARF	296	Q9UHQ1
ENLLSYDMHLHHDRG	NEUROD2	356	Q15784