Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

6.65e-0651763GO:0030156
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH3 TDRD9 DDX52 CHD7 ATP9A ATP10A CHTF18 HELZ2 MACF1 DDX20 DDX21 KIF2C AFG1L

1.52e-0444117613GO:0016887
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO1 NOMO2 TMCO1 NOMO3

5.83e-0791734GO:0160063
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO1 NOMO2 TMCO1 NOMO3

5.28e-0791714GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO1 NOMO2 TMCO1 NOMO3

4.06e-06141714GO:0072379
DomainDUF2012

NOMO1 NOMO2 NOMO3

3.10e-0641733PF09430
DomainDUF2012

NOMO1 NOMO2 NOMO3

3.10e-0641733IPR019008
Domain-

TANC2 PIK3AP1 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

2.06e-05248173111.25.40.20
DomainAnkyrin_rpt-contain_dom

TANC2 PIK3AP1 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

2.57e-0525417311IPR020683
DomainAnk_2

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

3.30e-0521517310PF12796
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

4.23e-0581733IPR013784
DomainAnk

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

5.41e-0522817310PF00023
DomainPHD

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

6.87e-05751736PF00628
DomainENOYL_COA_HYDRATASE

ECH1 ECHS1 ECHDC3

8.94e-05101733PS00166
DomainZnf_PHD-finger

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

9.20e-05791736IPR019787
DomainANK

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

1.20e-0425117310SM00248
DomainANK_REPEAT

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

1.28e-0425317310PS50088
DomainANK_REP_REGION

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

1.32e-0425417310PS50297
DomainAnkyrin_rpt

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

1.70e-0426217310IPR002110
DomainPHD

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

1.78e-04891736SM00249
DomainZnf_PHD

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

2.01e-04911736IPR001965
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

2.09e-04131733IPR014766
Domain-

NOMO1 NOMO2 NOMO3

2.09e-041317332.60.40.1120
DomainZF_PHD_2

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

2.55e-04951736PS50016
DomainZF_PHD_1

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

2.70e-04961736PS01359
DomainUBA

LATS2 UBAP2L UBQLN3 RAD23B

3.32e-04361734PF00627
DomainZnf_FYVE_PHD

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D FGD6

4.45e-041471737IPR011011
DomainCarboxyPept-like_regulatory

NOMO1 NOMO2 NOMO3

4.83e-04171733IPR008969
DomainECH_1

ECH1 ECHS1 ECHDC3

4.83e-04171733PF00378
DomainCrotonase_core_superfam

ECH1 ECHS1 ECHDC3

4.83e-04171733IPR001753
DomainPecanex_C

PCNX3 PCNX2

5.06e-0441732PF05041
DomainPecanex

PCNX3 PCNX2

5.06e-0441732IPR007735
DomainUBA

LATS2 UBAP2L UBQLN3 RAD23B

7.23e-04441734IPR015940
DomainFYrich_C

KMT2C KMT2D

8.38e-0451732IPR003889
DomainFYrich_N

KMT2C KMT2D

8.38e-0451732IPR003888
DomainCrontonase_C

ECH1 ECHS1

8.38e-0451732IPR014748
DomainFYRC

KMT2C KMT2D

8.38e-0451732SM00542
DomainFYRN

KMT2C KMT2D

8.38e-0451732SM00541
DomainPKD_2

PKDREJ PKD2L2

8.38e-0451732IPR003915
DomainFYRN

KMT2C KMT2D

8.38e-0451732PF05964
DomainFYRC

KMT2C KMT2D

8.38e-0451732PF05965
DomainFYRC

KMT2C KMT2D

8.38e-0451732PS51543
DomainFYRN

KMT2C KMT2D

8.38e-0451732PS51542
Domain-

ECH1 ECHS1 ECHDC3

9.19e-042117333.90.226.10
DomainClpP/crotonase-like_dom

ECH1 ECHS1 ECHDC3

9.19e-04211733IPR029045
DomainUBA

LATS2 UBAP2L UBQLN3 RAD23B

9.30e-04471734PS50030
DomainSH3

TRIO PPP1R13B RIMBP3 TJP1 MACF1 RIMBP3C ARHGEF37 RIMBP3B

9.30e-042161738PS50002
DomainSH3_domain

TRIO PPP1R13B RIMBP3 TJP1 MACF1 RIMBP3C ARHGEF37 RIMBP3B

1.05e-032201738IPR001452
DomainEPHD

BRPF3 KMT2C KMT2D

1.06e-03221733PS51805
DomainSpectrin

TRIO SPTBN5 MACF1

1.21e-03231733PF00435
DomainSH3_2

RIMBP3 TJP1 RIMBP3C ARHGEF37 RIMBP3B

1.22e-03861735PF07653
DomainSH3_2

RIMBP3 TJP1 RIMBP3C ARHGEF37 RIMBP3B

1.22e-03861735IPR011511
DomainRPEL

PHACTR2 MYOCD

1.74e-0371732PS51073
DomainRPEL

PHACTR2 MYOCD

1.74e-0371732SM00707
DomainRPEL

PHACTR2 MYOCD

1.74e-0371732PF02755
DomainRPEL_repeat

PHACTR2 MYOCD

1.74e-0371732IPR004018
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MED6 FYTTD1 GALNT3 PCNX3 MED16 RBM33 NT5E DDX52 TRPS1 DIDO1 CHD7 URB2 ATP9A VIRMA NOMO1 PCF11 KMT2C MYOF URB1 INTS2 EIF2S1 TPX2 HELZ2 MACF1 DDX20 TMCO1 MED12 CEP170B NR1I3 KIF2C RAD23B

3.19e-1114971783131527615
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MTA2 FYTTD1 SPOUT1 IQGAP2 MED16 DDX52 DIDO1 SAMHD1 URB2 MCM10 VIRMA URB1 UBAP2L EIF2S1 TPX2 MACF1 DDX21 MED12 KIF2C

1.50e-087591781935915203
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

4.57e-088178412634303
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 FYTTD1 LIMD1 TRIO TRPS1 LAMA3 PLD3 ECH1 ATP10A ESCO1 TFAP4 HPS3 TASOR2 PCNX2 PIAS4 KMT2C LATS2 INTS2 UBAP2L TJP1 EXOC6B MACF1 ARHGEF37 CATSPERG CEP170B NLK

4.76e-0814891782628611215
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MTA2 TANC2 SPOUT1 PCNX3 TRIO AOC2 ARHGAP17 MIB2 TRAK1 PCNX2 PIAS4 PLEKHG1 KMT2C MYOF URB1 FAT1 KMT2D LATS2 HELZ2 MED12 ABTB2 CEP170B

6.08e-0811051782235748872
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO1 NOMO2 TMCO1 NOMO3

8.19e-089178436261522
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 PHACTR2 LIMD1 TRIO ARHGAP17 VIRMA SYDE1 TRAK1 PLEKHG1 STX5 TJP1 PKP2 MACF1 FGD6 GEN1 ABTB2 CEP170B KIF2C DYRK2

1.08e-078611781936931259
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

1.32e-073178336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

1.32e-073178325576386
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SECISBP2L MTA2 FYTTD1 SPOUT1 IQGAP2 DDX52 DIDO1 SAMHD1 CHD7 PLD3 CWC25 ECH1 ECHS1 VIRMA PSMA8 PCF11 UBAP2L TJP1 TPX2 HELZ2 PKP2 DDX20 DDX21 RAD23B

1.58e-0713711782436244648
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO1 NOMO2 TMCO1 NOMO3

2.13e-0711178432820719
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

5.25e-074178331833031
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

5.25e-074178319091768
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

5.25e-07417839267806
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

1.31e-065178317855024
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MTA2 DDX52 DIDO1 CHD7 URB2 VIRMA TASOR2 URB1 UBAP2L TJP1 HELZ2 MACF1 DDX20 DDX21 MED12

1.54e-066531781522586326
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

TDRD9 TRIO ESCO1 RYR3 ERMN IL1RAPL1 TBX18 AFAP1L2 UBAP2L CHTF18

2.29e-062841781029459677
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 RBM33 PPP1R13B ARHGAP17 CHD7 RIMBP3 PIAS4 NOMO2 WDCP MACF1 YY1AP1 DDX20 CEP170B KIF2C

2.30e-065881781438580884
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FYTTD1 CAND2 SPOUT1 IQGAP2 DDX52 DIDO1 CHD7 KMT2C URB1 STX5 INTS2 UBAP2L LRP2 MACF1 RP2 COG5 DDX21 GEN1 KIF2C

3.34e-0610841781911544199
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MTA2 MED6 MED16 RBM33 C9orf78 DIDO1 CHD7 COPS3 TFAP4 PCF11 KMT2C KMT2D EIF2S1 TPX2 RPUSD2 MED12 PLIN3 KIF2C RAD23B

4.29e-0611031781934189442
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

GRIN1 KMT2C KMT2D

4.54e-067178319556342
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TANC2 FYTTD1 ARHGAP40 LIMD1 TRIO RBM33 C9orf78 ARHGAP17 ECH1 VIRMA SYDE1 PLEKHG1 UBAP2L TPX2 PKP2 ELANE FGD6

5.37e-069161781732203420
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MTA2 SLK LIMD1 PPP1R13B DIDO1 KMT2C KMT2D UBAP2L TJP1 TPX2 MED12 PLIN3 ELP4

5.67e-065491781338280479
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO1 NOMO2 NOMO3

7.24e-068178315257293
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SLK URB2 ATP9A VIRMA TRAK1 PLEKHG1 UBAP2L BRINP2 MACF1 YY1AP1 CEP170B

8.94e-064071781112693553
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MED6 MED16 RBM33 TRPS1 CHD7 PCF11 KMT2D TPX2 MED12

1.09e-05268178933640491
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

C9orf78 DIDO1 CHD7 VIRMA TFAP4 PCF11 MYOF KMT2D UBAP2L CHTF18 TPX2 HELZ2 YY1AP1 DDX20 DDX21

1.18e-057741781515302935
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

ITGA2B PLD3 NOMO1 MYOF NOMO2 LACC1 UBAP2L PAFAH1B2 HELZ2 NOMO3

1.23e-053441781030333137
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

TRIO TRPS1 MCM10 PLD3 CXXC1 SYDE1 KMT2C COL24A1 FAT1 AFAP1L2 RIMBP3C CATSPERG FGD6 NR1I3

1.39e-056891781436543142
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 BRPF3 PLEKHG1 MYOF INTS2 MACF1

1.57e-05103178610574462
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SECISBP2L MTA2 TANC2 CAND2 IQGAP2 CCDC150 COPS3 CWC25 ECHS1 SYDE1 NOMO1 POSTN WDCP PAFAH1B2 EXOC6B DDX20 RP2 FGD6 KIF2C DYRK2

1.57e-0513211782027173435
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MTA2 MYH3 SLK TRIO MED16 NOMO1 PIGQ MYOF LATS2 INTS2 NOMO2 TPX2 BCAR3 NOMO3 DYRK2 RAD23B

1.99e-059101781636736316
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

MTA2 MED6 FYTTD1 DIDO1 SAMHD1 ECH1 PSMA8 TASOR2 UBAP2L EIF2S1 DDX20 DDX21 MED12

2.19e-056241781333729478
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

2.60e-052178231924266
Pubmed

Sulf1A and HGF regulate satellite-cell growth.

HGF SULF1

2.60e-052178220442248
Pubmed

CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.

CHD7 KMT2D

2.60e-052178228475860
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

2.60e-052178228967912
Pubmed

Inhibition of apoptosis in periodontitis.

TNFSF10 TNFRSF10D

2.60e-052178219948942
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

2.60e-052178236601880
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

2.60e-052178228483418
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

2.60e-052178234156443
Pubmed

CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis.

TNFSF10 NT5E

2.60e-052178218566412
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

2.60e-052178227280393
Pubmed

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells.

TNFSF10 EIF2S1

2.60e-052178224525736
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

2.60e-052178236869380
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

2.60e-052178225346535
Pubmed

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain.

TNFSF10 TNFRSF10D

2.60e-05217829430226
Pubmed

Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression.

MYOF TJP1

2.60e-052178222808170
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

CXXC1 KMT2C KMT2D

2.80e-0512178327563068
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH3 SPOUT1 SAMHD1 GRIN1 ANKRD20A3P CXXC1 ESCO1 KMT2C URB1 AFAP1L2 RANBP3L PKHD1 LRP2 ELP4

2.86e-057361781429676528
Pubmed

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.

MED6 MED16 MED12

3.63e-0513178314657022
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

4.60e-0514178317662146
Pubmed

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.

CHD7 COPS3 TFAP4 PIAS4 CHTF18 TPX2 DDX21

4.66e-05183178736129980
Pubmed

Human transcription factor protein interaction networks.

SLK LIMD1 RBM33 DDX52 TRPS1 PPP1R13B DIDO1 CHD7 ECH1 CXXC1 TFAP4 PCF11 KMT2C FAT1 KMT2D UBAP2L WDCP TPX2 LRP2 YY1AP1

4.74e-0514291782035140242
Pubmed

Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.

MYH3 MED6 MED16 MED12

4.74e-0539178438690566
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

SLK DIDO1 MYOF UBAP2L TJP1 EIF2S1 TPX2 ELP4

5.61e-05256178833397691
Pubmed

Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction.

PPP1R13B ITGA2B ELANE

5.73e-0515178329853539
Pubmed

Functional proteomics mapping of a human signaling pathway.

LIMD1 PPP1R13B BTBD2 TRAK1 NOMO1 PIGQ PIAS4 KMT2D PKP2 MACF1 PLIN3 NOMO3

5.83e-055911781215231748
Pubmed

The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.

MED6 MED16 MED12

7.03e-0516178310882111
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

RBM33 C9orf78 ARHGAP17 COPS3 NOMO1 PCF11 NOMO2 EIF2S1 NOMO3 RAD23B

7.35e-054251781024999758
Pubmed

Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.

TNFSF10 TNFRSF10D

7.79e-053178226050621
Pubmed

Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).

CHD7 KMT2D

7.79e-053178228007623
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

7.79e-053178223932714
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

7.79e-053178222183980
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

7.79e-053178221683083
Pubmed

Ontogeny of expression of a receptor for platelet-activating factor in mouse preimplantation embryos and the effects of fertilization and culture in vitro on its expression.

PTAFR PAFAH1B2

7.79e-053178210026115
Pubmed

Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2).

PKDREJ PKD2L2

7.79e-053178210602361
Pubmed

Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A.

ESCO1 CHTF18

7.79e-053178223755103
Pubmed

The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8.

HECTD3 TNFSF10

7.79e-053178224287696
Pubmed

Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.

FAT1 KMT2D

7.79e-053178231123786
Pubmed

Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells.

TNFSF10 TNFRSF10D

7.79e-053178215916713
Pubmed

ELF3 plays an important role in defining TRAIL sensitivity in breast cancer by modulating the expression of decoy receptor 2 (DCR2).

TNFSF10 TNFRSF10D

7.79e-053178238787503
Pubmed

hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling.

HGF SULF1

7.79e-053178214699503
Pubmed

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

MED6 MED16 MED12

8.50e-0517178310235266
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SLK SPOUT1 LIMD1 RBM33 MYOF URB1 UBAP2L TJP1 MACF1 TMCO1 DDX21 GEN1 PLIN3

9.90e-057241781336232890
Pubmed

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

MED6 MED16 MED12

1.02e-0418178310198638
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

TFAP4 NOMO1 PIGQ NOMO2 NOMO3

1.03e-0490178515616553
Pubmed

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.

MED6 MED16 CXXC1 KMT2C

1.08e-0448178427703004
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 LIMD1 PPP1R13B ECH1 PLEKHG1 LATS2 TJP1 PKP2 CEP170B KIF2C

1.09e-044461781024255178
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PIK3AP1 TRIO RBM33 ARHGAP17 CHD7 MCM10 PLD3 CWC25 NOMO2 TJP1 TPX2 DDX20 ELP4

1.12e-047331781334672954
Pubmed

Defining the membrane proteome of NK cells.

MTA2 HGF MED6 MED16 DDX52 ECH1 NOMO1 INTS2 EIF2S1 CHTF18 HELZ2 DDX20 COG5 DDX21 MED12 PLIN3 KIF2C

1.13e-0411681781719946888
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MTA2 MED6 FYTTD1 DDX52 ING5 DIDO1 CHD7 CXXC1 ESCO1 TFAP4 KMT2C URB1 KMT2D INTS2 TPX2 DDX21 KIF2C RAD23B

1.25e-0412941781830804502
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

CXXC1 SPRYD7 KMT2C KMT2D

1.27e-0450178437974198
Pubmed

DNA sequence and analysis of human chromosome 9.

NPR2 SPOUT1 C9orf78 ANKRD20A2P ANKRD20A3P FREM1 ANKRD20A4P ANKRD20A1 RAD23B

1.32e-04370178915164053
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

MED6 SLK MED16 C9orf78 MCM10 ECH1 UBAP2L TPX2 MED12 PLIN3 KIF2C RAD23B

1.33e-046451781225281560
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PIK3AP1 FYTTD1 SAMHD1 MCM10 CXXC1 TRAK1 FAR2 INTS2 SULF1 YY1AP1 ELP4 ANKRD20A1 CFAP46

1.40e-047501781311230166
Pubmed

The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus.

PLEKHG1 KMT2C KMT2D

1.41e-0420178333431871
Pubmed

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.

MED6 MED16 MED12

1.41e-0420178315340084
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2D

1.55e-044178219221051
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C KMT2D

1.55e-044178234645806
Pubmed

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

PPP1R13B LATS2

1.55e-044178221041411
Pubmed

Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2.

MIB2 FAT1

1.55e-044178237031213
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C KMT2D

1.55e-044178228398509
Pubmed

Differential expression of TRAIL and TRAIL receptors in allergic asthmatics following segmental antigen challenge: evidence for a role of TRAIL in eosinophil survival.

TNFSF10 TNFRSF10D

1.55e-044178212421985
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2C KMT2D

1.55e-044178223129768
Pubmed

The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.

KMT2C KMT2D

1.55e-044178224081332
Pubmed

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.

LMOD1 MYOCD

1.55e-044178227144530
Pubmed

Respiratory syncytial virus infection sensitizes cells to apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.

TNFSF10 TNFRSF10D

1.55e-044178212915532
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

PHACTR2 PCNX3 RBM33 AOC2 DIDO1 ERVK-10 FREM1 TASOR2 FAT1 AFAP1L2 TJP1 SULF1 BCAR3 TMCO1 CEP170B CFAP46 DYRK2

1.81e-0412151781715146197
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

MTA2 SPOUT1 HECTD3 DDX52 TRPS1 SAMHD1 NOMO1 DDX20 PLCD1 CATSPERG NOMO3 KIF2C

1.88e-046701781222990118
Cytoband2q24-q31

GALNT3 LRP2

4.47e-05317822q24-q31
GeneFamilyAnkyrin repeat domain containing

TANC2 PPP1R13B ANKRD20A2P MIB2 ANKRD20A3P ANKS4B ANKRD20A4P GABPB2 ABTB2 ANKRD20A1

2.23e-0624211010403
GeneFamilyPHD finger proteins

BRPF3 ING5 DIDO1 CXXC1 KMT2C KMT2D

1.82e-0590110688
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO PLEKHG1 ARHGEF37 FGD6

6.99e-04661104722
GeneFamilyCyclins|Mediator complex

MED6 MED16 MED12

1.05e-033311031061
GeneFamilyDEAD-box helicases

DDX52 DDX20 DDX21

2.12e-03421103499
GeneFamilySmall leucine rich repeat proteoglycans

KERA PODN

2.33e-03121102573
GeneFamilyATPase phospholipid transporting

ATP9A ATP10A

3.66e-031511021210
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA2 TRPS1

3.66e-0315110282
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA2 BDP1 CHD7

4.12e-03531103532
CoexpressionBLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP

AOC2 SAMHD1 POSTN NOMO2 HELZ2 EXOC6B MACF1 NOMO3

4.04e-061371758M34024
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

TRIO BTBD2 TRAK1 SPRYD7 PCF11 POSTN OLFML2A UBA7 TJP1 SULF1 LMOD1 PLCD1 CEP170B DYRK2

4.81e-0648217514M12144
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_21_PRECICTIVE_ICB_RESISTANCE

SPOUT1 TFAP4 NOMO1 ECHDC3 NOMO2 EIF2S1 LRP2 DDX21 NOMO3

1.07e-052061759MM17087
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

SLK IQGAP2 ATP10A RYR3 FAT1 TJP1 SULF1 MACF1 NLK

1.35e-052121759M39221
CoexpressionHEVNER_CORTEX_RADIAL_GLIA_PROGENITORS

MED6 PHACTR2 CAND2 IQGAP2 MCM10 FAT1 GABPB2 TJP1 TPX2 LRP2 ELP4 NLK

3.61e-0543217512MM419
CoexpressionFOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN

PIK3AP1 HGF FYTTD1 TDRD9 TNFSF10 CHD7 ITGA2B URB1 LATS2 LACC1 HELZ2 ELANE LOXL3 ARHGEF37 FGD6 CFAP46

4.33e-0574617516M40863
CoexpressionCUI_TCF21_TARGETS_2_DN

SECISBP2L SLK IQGAP2 NT5E NADK2 PPP1R13B ARHGAP17 ATP10A ESCO1 SGPP1 PLEKHG1 KMT2C MYOF AFAP1L2 LATS2 MACF1 NLK

6.25e-0585417517M1533
CoexpressionGSE27786_LIN_NEG_VS_NKTCELL_DN

FYTTD1 LIMD1 TNFSF10 ATP10A CXXC1 PIAS4 KMT2D HELZ2

6.25e-052001758M4788
CoexpressionGSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP

PIK3AP1 GALNT3 TRPS1 ATP10A ELANE MYOCD BCAR3 ARHGEF37

6.25e-052001758M7490
CoexpressionGSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN

FYTTD1 TRIO RBM33 TRPS1 CHD7 KMT2D GABPB2 DYRK2

6.25e-052001758M8997
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR2 PTAFR FREM1 TRAK1 SGPP1 IL1RAPL1 AFAP1L2 PKHD1 ABTB2

7.01e-08189177990aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

MYH3 ITGA2B PSMA8 RYR3 COL24A1 TPX2 KIF2C AFG1L

3.64e-071671778315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PHACTR2 FREM1 SGPP1 IL1RAPL1 AFAP1L2 PKHD1 ABTB2

9.29e-0718917788ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

LAMA3 ATP10A RYR3 MYOF SULF1 LMOD1 MACF1 MYOCD

9.29e-0718917786b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PHACTR2 PTAFR FREM1 IL1RAPL1 AFAP1L2 PKHD1 ABTB2

9.66e-0719017784836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

NT5E TRPS1 PTAFR ATP10A POSTN MYOF SULF1 PODN

1.01e-06191177880d30d8eedb4c70b58440646325bc04c5700803e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PTAFR FREM1 TRAK1 SGPP1 IL1RAPL1 AFAP1L2 ABTB2

1.01e-06191177896b78b4e819ea6052334bfcbc7abbf35897df885
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TRIO TNFSF10 CHD7 KMT2C TJP1 MACF1 PLEKHO1 FGD6

1.42e-062001778dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF FREM1 IL1RAPL1 TBX18 COL24A1 SULF1 PODN CEP126

1.42e-062001778fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 RYR3 COL24A1 SULF1 PKHD1 LRP2 MYOCD

3.64e-061601777c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 RYR3 COL24A1 SULF1 PKHD1 LRP2 MYOCD

3.64e-06160177725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ITGA2B MCM10 RYR3 COL24A1 TPX2 KIF2C AFG1L

5.64e-0617117774ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell367C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PPP1R13B ARHGAP17 ECHDC3 AFAP1L2 LATS2 PLCD1 CEP126

7.61e-0617917775aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR2 PTAFR FREM1 TRAK1 SGPP1 IL1RAPL1 ABTB2

7.89e-061801777788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPS1 PTAFR FREM1 RYR3 COL24A1 AFAP1L2 VWA2

8.48e-06182177772e65a23cd36085bc880087d3cae92395de918a1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 TRAK1 SGPP1 IL1RAPL1 AFAP1L2 BCAR3 ABTB2

8.79e-061831777d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 RYR3 COL24A1 FAT1 PKHD1 LRP2 MYOCD

9.10e-0618417772cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 RYR3 COL24A1 FAT1 PKHD1 LRP2 MYOCD

9.10e-061841777ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 RYR3 COL24A1 FAT1 PKHD1 LRP2 MYOCD

9.10e-0618417772b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 GALNT3 PLD3 ATP10A PLEKHG1 MYOF BCAR3

9.77e-061861777f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 LAMA3 ATP9A MYOF AFAP1L2 RHPN2 SULF1

9.77e-061861777c116cc9f41971622264434ebe29d18e719b0ae19
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 GALNT3 PLD3 ATP10A PLEKHG1 MYOF BCAR3

9.77e-0618617778f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 LAMA3 PTAFR MYOF PKHD1 PLCD1 ABTB2

1.01e-05187177777886f99c229610abd28c4c370d2c7d1536c9782
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRPS1 POSTN PLEKHG1 COL24A1 FAT1 LMOD1 MYOCD

1.01e-051871777c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

LAMA3 ATP10A RYR3 MYOF LMOD1 MACF1 MYOCD

1.05e-05188177734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTAFR FREM1 TRAK1 SGPP1 IL1RAPL1 AFAP1L2 ABTB2

1.05e-0518817774154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 NEK10 FREM1 IL1RAPL1 PKHD1 ABTB2 NLK

1.16e-0519117773e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Mup5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH3 ATP10A SULF1 PODN MYOCD NR1I3

1.19e-0512717766df92f80b8922ca00eb383f79cd8dda4d602adfc
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

POSTN PLEKHG1 COL24A1 FAT1 LMOD1 MYOCD ABTB2

1.20e-05192177772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SECISBP2L BDP1 TRIO PLEKHG1 EXOC6B YY1AP1 DDX21

1.24e-05193177708696a99309f5b088692ddac8cca35413b5e810d
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

TRIO CHD7 TRAK1 SGPP1 PLEKHG1 BCAR3 GEN1

1.24e-0519317777ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

PHACTR2 ERMN POSTN OLFML2A MYOF SULF1 LMOD1

1.28e-051941777638b9fdce64ed00243b5303800ec66207d5fd640
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

PHACTR2 ERMN POSTN OLFML2A MYOF SULF1 LMOD1

1.28e-051941777e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 NEK10 FREM1 IL1RAPL1 PKHD1 ABTB2 NLK

1.28e-05194177704bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TRIO FAT1 PKHD1 BCAR3 ABTB2 NLK

1.28e-05194177746070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TRIO FAT1 PKHD1 BCAR3 ABTB2 NLK

1.28e-051941777abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 NEK10 FREM1 IL1RAPL1 PKHD1 ABTB2 NLK

1.28e-05194177769bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ARHGAP40 TRIO PTAFR PLEKHG1 MYOF PKHD1

1.33e-051951777938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ARHGAP40 TRIO PTAFR PLEKHG1 MYOF PKHD1

1.33e-051951777d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10A POSTN TBX18 SULF1 CNTN5 LMOD1 MYOCD

1.37e-0519617771522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellBronchial-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SAMHD1 SHISA4 IL1RAPL1 OLFML2A AFAP1L2 LMOD1 ANKRD20A1

1.37e-051961777a90c76d9c57a4491b94a321ba541b792ec5d8e83
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNFSF10 ITGA2B PLD3 RYR3 SGPP1 PKP2 MACF1

1.37e-0519617775bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10A POSTN TBX18 SULF1 CNTN5 LMOD1 MYOCD

1.37e-0519617771c8294014713684b50885e638668f2ce75f357f0
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IQGAP2 KMT2C FAR2 TPX2 ELANE CEP170B KIF2C

1.42e-05197177770704b149b2820b8601d2495b7cd9cbe91eda262
ToppCellBronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SAMHD1 SHISA4 IL1RAPL1 OLFML2A AFAP1L2 LMOD1 ANKRD20A1

1.42e-0519717774a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC150 RYR3 POSTN TPX2 GEN1 KIF2C

1.48e-05132177602491930097b75aaeedab9e8200711b0dc610944
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 RBM33 SAMHD1 KMT2C HELZ2 MACF1 DDX21

1.56e-05200177712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PIK3AP1 TNFSF10 PTAFR MYOF HELZ2 PLEKHO1 FGD6

1.56e-05200177782126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

TANC2 TRIO DIDO1 PCF11 KMT2D FAR2

1.68e-051351776ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

OLFML2A STX5 RANBP3L UBAP2L CHTF18 CATSPERG

2.24e-0514217766a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

OLFML2A STX5 RANBP3L UBAP2L CHTF18 CATSPERG

2.24e-051421776671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

OLFML2A STX5 RANBP3L UBAP2L CHTF18 CATSPERG

2.24e-0514217763557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

OLFML2A STX5 RANBP3L UBAP2L CHTF18 CATSPERG

2.24e-051421776a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FAT1 KMT2D LATS2 TJP1 FGD6 ABTB2

2.42e-0514417760b94d978262a826c9254145aa98c6c30240243f9
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CAND2 RYR3 PIGQ COL24A1 MYOCD ARHGEF37

3.53e-05154177616fdafb5c64d2db321554f87129a962d113f1668
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HGF TDRD9 MED16 NEK10 AOC2 ABTB2

4.37e-051601776c2b5fadb4bac17fafc08831f6d3f4ff96ada7e70
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRPF3 SLK PTAFR ATP9A LACC1 ARHGEF37

5.19e-05165177694a5211072464fc24592bb107a853ce832e816fe
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

DYTN ITGA2B SYDE1 FREM1 FAT1 VWA2

5.37e-0516617769788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

HGF MYH3 TNFSF10 LACC1 HELZ2 PLEKHO1

5.55e-051671776ab6029ba037b6a499da8758864c44e174cde5587
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR2 PTAFR PKDREJ TRAK1 SGPP1 IL1RAPL1

5.93e-0516917760332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NT5E ING5 CHD7 PLEKHG1 URB1 HELZ2

6.33e-051711776bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HGF ITGA2B PLD3 SGPP1 BCAR3 NLK

6.33e-05171177682f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR2 PLD3 ATP9A PKD2L2 RHPN2 BRINP2

6.54e-051721776a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAND2 NADK2 FREM1 MYOF TPX2 KIF2C

6.54e-05172177629c8510f26527d487d0fc3543102d067cdb281a6
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR2 PLD3 ATP9A PKD2L2 RHPN2 BRINP2

6.54e-05172177665b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RYR3 COL24A1 ANKRD20A4P SULF1 VWA2 ANKRD20A1

6.97e-05174177699eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 ATP10A RYR3 FAT1 AFAP1L2 SULF1

7.19e-051751776a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PCNX2 IL1RAPL1 TBX18 SULF1 LRP2 PODN

7.90e-0517817761e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL1RAPL1 TBX18 RHPN2 SULF1 LRP2 PODN

7.90e-051781776bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL1RAPL1 TBX18 RHPN2 SULF1 LRP2 PODN

7.90e-051781776c413861148129be1ee94f2ceb5999840217eebe5
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

ECHDC3 WDCP CHTF18 TPX2 GEN1 AFG1L

8.15e-051791776ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCTE1 GRIN1 RYR3 PKP2 LOXL3 CATSPERG

8.15e-0517917764f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2A AFAP1L2 BRINP2 LMOD1 MYOCD BCAR3

8.40e-051801776a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2A AFAP1L2 BRINP2 LMOD1 MYOCD BCAR3

8.40e-05180177663a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRAK1 SGPP1 PIGQ AFAP1L2 BCAR3 ABTB2

8.40e-051801776023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPS1 FREM1 RYR3 COL24A1 MYOF VWA2

8.40e-051801776e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA2B FREM1 RYR3 COL24A1 TPX2 KIF2C

8.66e-051811776be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 LAMA3 MYOF AFAP1L2 TJP1 SULF1

8.93e-051821776c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 LAMA3 MYOF AFAP1L2 TJP1 SULF1

8.93e-051821776d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL1RAPL1 TBX18 SULF1 LRP2 PODN BCAR3

8.93e-0518217769966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPS1 PTAFR RYR3 COL24A1 AFAP1L2 VWA2

8.93e-05182177605c167158815bf25d509df59ab386e1990712765
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO TNFSF10 SAMHD1 KMT2C HELZ2 FGD6

9.20e-0518317768f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

SECISBP2L PIK3AP1 TNFSF10 PLEKHG1 HELZ2 PLEKHO1

9.20e-051831776dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 IQGAP2 FREM1 SGPP1 AFAP1L2 ABTB2

9.20e-051831776b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

AOC2 OLFML2A CHTF18 MYOCD DYRK2

9.24e-0511417752cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

AOC2 OLFML2A CHTF18 MYOCD DYRK2

9.24e-051141775fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-051841776a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-051841776081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-05184177645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-05184177684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P PKP2 ANKRD20A1

9.48e-05184177642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 GALNT3 PLD3 ATP10A MYOF BCAR3

9.48e-05184177615ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-051841776d31d4116d1d196633784863781fa45673607a421
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-051841776c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

TANC2 CHD7 ANKRD20A4P CHTF18 TPX2 ELANE

9.48e-0518417762fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 GALNT3 PLD3 ATP10A MYOF BCAR3

9.48e-051841776bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL1RAPL1 POSTN COL24A1 LMOD1 PODN MYOCD

9.76e-0518517766712512100ccef456d2e2bd201d0987986c92ac9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L ARHGAP40 LIMD1 PPP1R13B PLEKHG1 FAT1

9.76e-05185177698b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ATP10A RYR3 TJP1 SULF1 NLK

9.76e-0518517769197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL1RAPL1 POSTN COL24A1 LMOD1 PODN MYOCD

9.76e-0518517763b2dfc8f4c87be516265dbecfc251276034d0efd
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BDP1 SLK TASOR2 TJP1 MACF1

7.13e-0550945GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

3.03e-0521632DOID:0080598 (implicated_via_orthology)
Diseasemeningioma (is_marker_for)

HGF KMT2D

9.07e-0531632DOID:3565 (is_marker_for)
Diseasemalaria

MYH3 IL1RAPL1 PLEKHG1 EXOC6B DYRK2

2.62e-041021635EFO_0001068
DiseaseMalignant Cystosarcoma Phyllodes

KMT2D MED12

3.00e-0451632C0600066
DiseasePhyllodes Tumor

KMT2D MED12

3.00e-0451632C0010701
Diseaselung small cell carcinoma (is_implicated_in)

LAMA3 FAT1 KMT2D

4.90e-04281633DOID:5409 (is_implicated_in)
Diseasecongenital heart disease (implicated_via_orthology)

CHD7 KMT2C KMT2D LRP2

5.87e-04691634DOID:1682 (implicated_via_orthology)
Diseasebody surface area

BRPF3 TRPS1 KERA DIDO1 SAMHD1 TFAP4 SPRYD7 COL24A1 PKHD1 MACF1 AFG1L

9.36e-0464316311EFO_0022196
Diseaseprostate carcinoma

TANC2 HGF SLK TRIO TNFSF10 PPP1R13B CHD7 TFAP4 TASOR2 PKHD1 MYOCD CATSPERG RAD23B

1.40e-0389116313EFO_0001663
Diseaseamino acid measurement

TANC2 RYR3 ECHDC3 TBX18 COL24A1 FAR2 CNTN5 BRINP2 LRP2 ELANE MGAM2

1.43e-0367816311EFO_0005134
Diseasephysical activity

PCF11 PLEKHG1 CNTN5 PKHD1

1.46e-03881634EFO_0003940
Diseaseanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine

PHACTR2 MCM10

1.61e-03111632EFO_0803358, EFO_0803362
DiseaseSquamous cell carcinoma of esophagus

DIDO1 KMT2C FAT1 KMT2D

1.93e-03951634C0279626
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2C FAT1 KMT2D

1.98e-03451633DOID:3748 (is_implicated_in)
Diseasepleurisy (implicated_via_orthology)

PTAFR ELANE

2.27e-03131632DOID:10247 (implicated_via_orthology)
DiseaseLeft ventricular noncompaction

MIB2 PKP2

2.64e-03141632C1960469
Diseasecortical surface area measurement

TANC2 HGF NPR2 PCNX3 IQGAP2 CHD7 TFAP4 PIGQ PLEKHG1 COL24A1 TJP1 EXOC6B PKHD1 MACF1 FGD6 RAD23B

3.27e-03134516316EFO_0010736
DiseaseGlioblastoma Multiforme

TNFSF10 FAT1 NLK DYRK2

3.40e-031111634C1621958
Diseasemyopia (is_implicated_in)

HGF LOXL3

3.46e-03161632DOID:11830 (is_implicated_in)
Diseasecorneal resistance factor

KERA CWC25 CXXC1 TFAP4 COL24A1 MYOF RANBP3L TJP1

3.72e-034511638EFO_0010067
Diseaseresponse to phenylephrine

IQGAP2 ATP10A

3.91e-03171632EFO_0010152
Diseasecomplex trait

TRPS1 ARHGAP17 FREM1 PAFAH1B2 CHFR MACF1

4.06e-032711636EFO_0010578
Diseasespine bone mineral density

GALNT3 DDX52 CXXC1 RHPN2

4.36e-031191634EFO_0007701
Diseasefemoral neck bone mineral density

GALNT3 CXXC1 PCNX2 RHPN2 CNTN5

4.75e-031961635EFO_0007785
DiseaseAcute Myeloid Leukemia, M1

HGF TRIO TNFSF10 KMT2C

5.18e-031251634C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

HGF TRIO TNFSF10 KMT2C

5.18e-031251634C1879321

Protein segments in the cluster

PeptideGeneStartEntry
LLILQQQVNPRRAFG

URB2

181

Q14146
QRKNVQTLRAEQALP

ANKRD20A1

351

Q5TYW2
NQKGQLVKRLVPVEQ

CATSPERG

596

Q6ZRH7
NVLLSILNRKGPQEV

CHTF18

446

Q8WVB6
KPLLRSVANVIQQAG

DDX52

521

Q9Y2R4
QEGSQLKALRPVQVR

BDP1

691

A6H8Y1
LKRQRQVLQSTQSPR

AKAP2

736

Q9Y2D5
QRKNVQTLRAEQALP

ANKRD20A8P

351

Q5CZ79
RNQGLQGPLTAEQKR

CWC25

236

Q9NXE8
QLTNALVERKQPLRG

COPS3

106

Q9UNS2
VQAREQNLPRGNLLR

BCAR3

296

O75815
QNLPRGNLLRNKEKS

BCAR3

301

O75815
TLPRGQIVAILQNKD

ARHGEF37

526

A1IGU5
QRKNVQTLRAEQALP

ANKRD20A4P

351

Q4UJ75
RNRSKVAQQPLSLVG

AFAP1L2

386

Q8N4X5
QKQNDLTRPRILKVQ

AFG1L

316

Q8WV93
AKQLLQQQIGPRLGT

CFAP46

866

Q8IYW2
NGVKLQRSPDRVLEN

BRPF3

936

Q9ULD4
LSPKEIVQKVRNGQR

NPR2

731

P20594
PQNGFVRNKVIEQRV

DDX20

626

Q9UHI6
GEQVRLQRQIKRDPQ

CEP170B

381

Q9Y4F5
KTPGQRQLITLQEQV

PIK3AP1

601

Q6ZUJ8
NGRNNLVIDTPRVRK

CHD7

1546

Q9P2D1
RTQRNVINVPGEKRT

PPP1R13B

101

Q96KQ4
QGRVFPTQLQLARQL

ATP10A

1296

O60312
RLRKSQAVLEIPNVQ

CNTN5

346

O94779
ALLQQIGRENPQLLQ

RAD23B

301

P54727
FPGAQVRQNVKNRLL

RBM33

861

Q96EV2
RGTKTPINRNQLSQN

MTA2

536

O94776
LGPLKSVQELRREQQ

NOMO3

696

P69849
VGTARLNRKQIPNDL

PGBD4

351

Q96DM1
RGQDRQQQLQRDPQK

RIMBP3B

666

A6NNM3
RGQDRQQQLQRDPQK

RIMBP3C

666

A6NJZ7
QRKNVQTLRAEQALP

ANKRD20A2P

351

Q5SQ80
QRPQLTRQVLGKEDL

AOC2

556

O75106
QRRAQQTPVQLSKEQ

NR1I3

96

Q14994
NTGLISILEPVKRQQ

FAT1

416

Q14517
PKAGQTLQQRVFQIL

FAR2

46

Q96K12
NLQNNRLTSRGLPEK

PODN

126

Q7Z5L7
EVLRQLQTLAPKGVN

PLD3

146

Q8IV08
LRVLNLANNQVRAPG

TCTE1

336

Q5JU00
LGPLKSVQELRREQQ

NOMO2

696

Q5JPE7
QQQSKPQGEARVRLK

LOXL3

296

P58215
KQRGQRKERSPQQNI

KMT2C

191

Q8NEZ4
PPQKLQALQRVLQSR

LIN7B

31

Q9HAP6
VTLKAPQNQVTLRGR

LAMA3

1106

Q16787
RKIESINQQLLPLGN

LAMA3

2351

Q16787
QQQLLQEETLPRGSR

LIMD1

61

Q9UGP4
VRIQNNPFGIQIQRK

MGAM2

1041

Q2M2H8
RQRLQEIREGLKQPS

LATS2

16

Q9NRM7
NIAKRQGNLSLPLNR

NADK2

336

Q4G0N4
QRNGKLICTRENNPV

SPINK5

856

Q9NQ38
LINNINRRLTPQAVK

EIF2S1

176

P05198
RGKNNTVGLIQLNRP

ECHS1

41

P30084
RQLDGIRNIVLSNPK

ECHDC3

51

Q96DC8
LRNRNPERGSIQNNK

PCNX2

1796

A6NKB5
PERGSIQNNKQVLRN

PCNX2

1801

A6NKB5
RNPERGSIQNAKQAL

PCNX3

1751

Q9H6A9
SQRKVRQISDPIQQI

NEK10

1021

Q6ZWH5
LINGQRPQTKSSREQ

IL1RAPL1

656

Q9NZN1
PVGLRQRNQTEKQST

LMOD1

46

P29536
RLPKVIGNQSLVNEL

ECH1

211

Q13011
ERLPQNGQLQLKIGR

FREM1

1316

Q5H8C1
QIPIKFLIRQAQGLQ

INTS2

686

Q9H0H0
LNSGVPRRILQTVNK

INTS2

801

Q9H0H0
LGPLKSVQELRREQQ

NOMO1

696

Q15155
PKVVVQENLRRLANA

LACC1

221

Q8IV20
GENPQRQRIKRILQN

MED12

1336

Q93074
GANKIVLRDNVPNLR

LRP2

1991

P98164
NLIIQETRQKLGIPQ

MCM10

496

Q7L590
LNAINRRKQVLQQPG

ANKS4B

396

Q8N8V4
RRKQVLQQPGQLVDT

ANKS4B

401

Q8N8V4
APTQKAQIVRLLQER

ATP9A

761

O75110
DNIVLQQPRIGSKRK

EXOC6B

231

Q9Y2D4
KQLRVVNGIPTRTNI

HGF

491

P14210
QQIGTKLVRRLSQRP

PHACTR2

511

O75167
GRRILFQAQSPIQQL

NLK

336

Q9UBE8
EKIPLSGSNQEIRRQ

ERMN

116

Q8TAM6
QRRTQEQLANQGIIP

MYOCD

26

Q8IZQ8
PVGTQTAKIQQQIIR

MACF1

5481

Q9UPN3
LRKEGLPVNNIFQQI

MED16

311

Q9Y2X0
LNIRVISGQQLPKVN

PLCD1

631

P51178
QIQDLKGTNRDPRLN

PCF11

286

O94913
GNFQKRLPQIQRRAT

MCHR2

311

Q969V1
RILNLSKRLQGQLQG

COG5

181

Q9UP83
AGQVLVRLQPQKQVK

ERVK-10

186

P87889
QRKNVQTLRAEQALP

ANKRD20A3P

351

Q5VUR7
LDLNGQLLVAQPRRN

CHFR

266

Q96EP1
TQQQPQPSQKLGRIR

CXXC1

241

Q9P0U4
ALQPVQGLARQVRDI

BORCS6

331

Q96GS4
GLQLELTKNRLQRPS

CCDC150

1041

Q8NCX0
ARRQQLLDQVNPKGV

DYTN

306

A2CJ06
TKRRNILEQKRQNPG

CEP126

961

Q9P2H0
PKGTQVIARNQVRLA

GALNT3

426

Q14435
PNSQIRQNIRRSLKE

DIDO1

666

Q9BTC0
LSPDQRVERLQKIQN

ING5

56

Q8WYH8
ERKLGSRNSNQLQPI

GEN1

386

Q17RS7
QLQPIRIVKTRIRNG

GEN1

396

Q17RS7
ANVQVAQLPAQGRRL

ELANE

131

P08246
NPKANEQLNRRSQRL

ESCO1

111

Q5FWF5
DGSNPQKKQRNILRI

ELP4

241

Q96EB1
IPQKQREITLKGFRN

DDX21

471

Q9NR30
QLRPVVKNERLQNLG

HELZ2

2391

Q9BYK8
RQQLQVTPENRRKVL

BTBD2

296

Q9BX70
RGQVPLVVKALQRQL

CAND2

431

O75155
ANGNIQQRTVLPKLV

DYRK2

586

Q92630
PLQENVTIQKQKRRS

KIF2C

81

Q99661
LEPGLRVTVRLNQQQ

SPOUT1

221

Q5T280
IRKQQRQSPAQVIPL

MED6

81

O75586
IVQLINTRQPQAKII

PAFAH1B2

121

P68402
AKPRALAQQQAVIRG

OLFML2A

276

Q68BL7
LLRRRPEQVDTKNQG

MIB2

451

Q96AX9
RLKLEAIARQQPNGV

GABPB2

386

Q8TAK5
AVRAGRLQLNEKPVQ

RPUSD2

181

Q8IZ73
QAQQLAVRLEPQGLL

SYDE1

361

Q6ZW31
KNRQTQERARLPKIQ

SLK

1061

Q9H2G2
RQNIQKILGLAPSRA

TMCO1

206

Q9UM00
PNRAIRITKNQVSQL

SAMHD1

526

Q9Y3Z3
RVLAQLPVNQQLGKL

TDRD9

596

Q8NDG6
LEPRLLIQQRKGQIV

HPS3

711

Q969F9
LIQQRKGQIVPTELA

HPS3

716

Q969F9
RGQDRQQQLQRDPQK

RIMBP3

666

Q9UFD9
IPNIQKQRKQLARLV

ARHGAP17

131

Q68EM7
NRDRQIRNQQPLKSV

SPATA31A6

1276

Q5VVP1
QPVQQQRNAEVKRRA

PTAFR

216

P25105
RGQNTLRQLLAPVVK

IQGAP2

976

Q13576
VIQRVRINTDQKGAP

PKDREJ

216

Q9NTG1
LPTNVKDQVQQARRQ

PLIN3

351

O60664
IPIQVKQLLAQVRQA

PIGQ

41

Q9BRB3
QLQLARNKVSRIPQG

KERA

146

O60938
RLAQLVGRLQDPQKV

SGPP1

6

Q9BX95
RRRQQLQSPFEGQEI

SHISA4

116

Q96DD7
QGLRLQPAKAQIVRS

TANC2

1601

Q9HCD6
RNSNRGSVVPKQQLL

SECISBP2L

166

Q93073
VTRINQQLDTKLPRQ

MYH3

441

P11055
QERQQLPGQSRLSKQ

PKHD1

4026

P08F94
QLPNTLKQGIERVRA

SKIV2L

1126

Q15477
NAELQLDRQKPRQGR

ITGA2B

536

P08514
NPGQLSRIQDLVARK

PLEKHO1

301

Q53GL0
NPLAQTGRSKLQNQR

RHPN2

26

Q8IUC4
VATQKVNLNQIPLGR

SPRYD7

81

Q5W111
QSVLKELQNRRAGPA

URB1

1081

O60287
QGQTVQRRLTKILLQ

SPTBN5

286

Q9NRC6
NGIQTNKPALRAVRQ

STX5

76

Q13190
GHRNVLRKLLTQPQQ

ABTB2

661

Q8N961
GRRPNLQQVTENLIK

BRINP2

126

Q9C0B6
TKVQQIRRAEPNVLL

NT5E

66

P21589
RNKNRLQLGVQLLPK

COL24A1

126

Q17RW2
QQTVAPQQQRRSLKE

TNFRSF10D

66

Q9UBN6
VRNINQVVKQRSLTP

TRAK1

406

Q9UPV9
ANLLRQNEGQRKPVA

FYTTD1

141

Q96QD9
RPLNIIKQNNGEQII

TRPS1

931

Q9UHF7
KQRPQATAEQIRLAQ

UBAP2L

26

Q14157
VVPNIPNLKQRLQVL

ARHGAP40

371

Q5TG30
PVNRAQSKRIVGQII

UBA7

836

P41226
NQQITRLKIDRNPFA

TBX18

311

O95935
GIQQDLKNKRNPRLV

RYR3

1006

Q15413
NPRARKNRSQIVLFQ

SPDYE21

346

A0A494C086
RVLGTQKLTQPQLEN

RANBP3L

221

Q86VV4
RQLGKPVIEDRILNQ

FGD6

906

Q6ZV73
ANRSIVPISRGQRQK

RP2

216

O75695
PAQKLRNNGISVLVV

VWA2

651

Q5GFL6
LGVPRVRQLKVRNNT

PKD2L2

126

Q9NZM6
PQSVQVDGRARTQKL

TNXA

286

Q16473
KLVQVRNPLNVRNVG

ZNF780B

801

Q9Y6R6
IRNSRELQPGVKAVQ

PIAS4

176

Q8N2W9
NQQVEILGRRAEQLP

ZPBP

271

Q9BS86
QTLILDPAQRKRLQQ

YY1AP1

156

Q9H869
RGIIPNKNRAEQLAS

TJP1

571

Q07157
QKQRVNIVKGNENPR

TASOR2

461

Q5VWN6
NIVKGNENPRNRKQL

TASOR2

466

Q5VWN6
EVQNLRKRPNGVSAV

C9orf78

36

Q9NZ63
QKVVVVNRNLPLNAQ

PLEKHG1

1246

Q9ULL1
KQQNISPLVRERGPQ

TNFSF10

106

P50591
NIQQIRLENTERPKG

WDCP

376

Q9H6R7
RLLQGDTPVRKLQAN

POSTN

806

Q15063
GKNIELAIIRRNQPL

PSMA8

211

Q8TAA3
RGRIQQERKNIRPNI

SULF1

31

Q8IWU6
RQPIALNVRQLKAGT

VIRMA

446

Q69YN4
LNGVPRLLQVLKQTR

PKP2

436

Q99959
KLEREQQQLRTQLLP

TFAP4

211

Q01664
ANPRALQALRQIEQG

UBQLN3

516

Q9H347
QNDVRPIRSIKNFLQ

TRIO

3076

O75962
QGKTPLRKANLQQAI

TPX2

56

Q9ULW0
QVKQFLLLSRQRPGL

HECTD3

441

Q5T447
QLRAQLQGVLAKNPQ

KMT2D

4196

O14686
LRPTQLLQNVARFKG

MYOF

1671

Q9NZM1
RGALQNQKDTVLPRR

GRIN1

906

Q05586