Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of female receptivity	NCOA2 NCOA1	5.31e-05	4	62	2	GO:0045925
GeneOntologyBiologicalProcess	cellular response to Thyroglobulin triiodothyronine	NCOA2 NCOA1	5.31e-05	4	62	2	GO:1904017
Domain	DUF1518	NCOA2 NCOA1	3.46e-05	3	64	2	PF07469
Domain	DUF1518	NCOA2 NCOA1	3.46e-05	3	64	2	IPR010011
Domain	Nuc_rcpt_coact_Ncoa-typ	NCOA2 NCOA1	3.46e-05	3	64	2	IPR014920
Domain	SRC-1	NCOA2 NCOA1	3.46e-05	3	64	2	IPR014935
Domain	Src1_rcpt_coact	NCOA2 NCOA1	3.46e-05	3	64	2	IPR008955
Domain	Nuclear_rcpt_coactivator	NCOA2 NCOA1	3.46e-05	3	64	2	IPR017426
Domain	DUF1518	NCOA2 NCOA1	3.46e-05	3	64	2	SM01151
Domain	SRC-1	NCOA2 NCOA1	3.46e-05	3	64	2	PF08832
Domain	-	NCOA2 NCOA1	3.46e-05	3	64	2	4.10.630.10
Domain	Nuc_rec_co-act	NCOA2 NCOA1	3.46e-05	3	64	2	PF08815
Domain	Nuc_rcpt_coact	NCOA2 NCOA1	1.72e-04	6	64	2	IPR009110
Domain	WD40	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	2.57e-04	259	64	6	PF00400
Domain	WD40	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	3.08e-04	268	64	6	SM00320
Domain	WD40_repeat	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	3.34e-04	272	64	6	IPR001680
Domain	WD_REPEATS_1	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	3.75e-04	278	64	6	PS00678
Domain	WD_REPEATS_2	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	3.82e-04	279	64	6	PS50082
Domain	WD_REPEATS_REGION	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	3.82e-04	279	64	6	PS50294
Domain	WD40_repeat_dom	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	5.32e-04	297	64	6	IPR017986
Domain	Hist_deacetyl	HDAC10 HDAC2	6.23e-04	11	64	2	PF00850
Domain	His_deacetylse_dom	HDAC10 HDAC2	6.23e-04	11	64	2	IPR023801
Domain	-	HDAC10 HDAC2	6.23e-04	11	64	2	3.40.800.20
Domain	His_deacetylse	HDAC10 HDAC2	6.23e-04	11	64	2	IPR000286
Domain	-	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	9.65e-04	333	64	6	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	9.95e-04	335	64	6	IPR015943
Domain	-	CRNN NINL PLCD1 RCN3 STAT5A	2.00e-03	261	64	5	1.10.238.10
Domain	EFh	CRNN NINL PLCD1 RCN3	2.11e-03	158	64	4	SM00054
Domain	-	RTKN2 MYO7A PLEKHA4 EPB41L5 PLCD1 RASAL1	2.18e-03	391	64	6	2.30.29.30
Domain	WD40_repeat_CS	WDR97 KIF21A WDSUB1 HIRA	2.42e-03	164	64	4	IPR019775
Domain	EF-hand-dom_pair	CRNN NINL PLCD1 RCN3 STAT5A	3.01e-03	287	64	5	IPR011992
Domain	EF_Hand_1_Ca_BS	CRNN NINL PLCD1 RCN3	3.06e-03	175	64	4	IPR018247
Domain	PAS	NCOA2 NCOA1	3.30e-03	25	64	2	PF00989
Domain	PAS_fold	NCOA2 NCOA1	3.30e-03	25	64	2	IPR013767
Domain	PH_dom-like	RTKN2 MYO7A PLEKHA4 EPB41L5 PLCD1 RASAL1	3.34e-03	426	64	6	IPR011993
Domain	EF_HAND_1	CRNN NINL PLCD1 RCN3	5.27e-03	204	64	4	PS00018
Domain	PAS	NCOA2 NCOA1	5.37e-03	32	64	2	SM00091
Domain	FERM_N	MYO7A EPB41L5	5.70e-03	33	64	2	PF09379
Domain	FERM_N	MYO7A EPB41L5	5.70e-03	33	64	2	IPR018979
Domain	PAS	NCOA2 NCOA1	6.04e-03	34	64	2	IPR000014
Domain	PAS	NCOA2 NCOA1	6.04e-03	34	64	2	PS50112
Domain	PH	RTKN2 PLEKHA4 PLCD1 RASAL1	7.88e-03	229	64	4	PF00169
Domain	EF_HAND_2	CRNN NINL PLCD1 RCN3	8.11e-03	231	64	4	PS50222
Domain	EF_hand_dom	CRNN NINL PLCD1 RCN3	8.24e-03	232	64	4	IPR002048
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL	NCOA2 CYP8B1 NCOA1	1.23e-05	14	47	3	M27074
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL	NCOA2 CYP8B1 NCOA1	1.23e-05	14	47	3	MM14748
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	TXNRD1 NCOA2 NRF1 MTF1 NCOA1	4.37e-05	118	47	5	M27316
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	NCOA2 CYP8B1 NCOA1	5.87e-05	23	47	3	M1926
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	NCOA2 CYP8B1 NCOA1	5.87e-05	23	47	3	MM14741
Pathway	REACTOME_ENDOGENOUS_STEROLS	NCOA2 CYP8B1 NCOA1	7.59e-05	25	47	3	M11184
Pathway	REACTOME_ENDOGENOUS_STEROLS	NCOA2 CYP8B1 NCOA1	9.61e-05	27	47	3	MM14844
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	HDAC10 MAML3 HDAC2	1.07e-04	28	47	3	M6177
Pathway	PID_REG_GR_PATHWAY	NCOA2 NCOA1 STAT5A HDAC2	1.57e-04	82	47	4	M115
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS	NCOA2 CYP8B1 NCOA1	1.77e-04	33	47	3	M5967
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS	NCOA2 CYP8B1 NCOA1	1.77e-04	33	47	3	MM14737
Pathway	REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	NCOA2 MTF1 NCOA1	3.64e-04	42	47	3	M27172
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	NCOA2 CYP8B1 NCOA1	4.18e-04	44	47	3	M499
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	NCOA2 CYP8B1 NCOA1	4.47e-04	45	47	3	MM14751
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	HDAC10 MAML3 HDAC2	5.41e-04	48	47	3	M611
Pathway	KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY	NCOA2 NCOA1	5.87e-04	11	47	2	M47503
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS	NCOA2 NRF1 NCOA1	8.07e-04	55	47	3	M27145
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	NCOA2 MTF1 NCOA1	8.07e-04	55	47	3	M27001
Pathway	BIOCARTA_EXTRINSIC_PATHWAY	FGB PROS1	8.29e-04	13	47	2	M4470
Pathway	BIOCARTA_EXTRINSIC_PATHWAY	FGB PROS1	8.29e-04	13	47	2	MM1395
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	HDAC10 MAML3 HDAC2	9.42e-04	58	47	3	M29616
Pathway	PID_ERB_GENOMIC_PATHWAY	NCOA2 NCOA1	1.11e-03	15	47	2	M119
Pathway	PID_ERA_GENOMIC_PATHWAY	NCOA2 NCOA1 STAT5A	1.25e-03	64	47	3	M200
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	NCOA2 CYP8B1 NCOA1	1.25e-03	64	47	3	M5650
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	NCOA2 CYP8B1 NCOA1	1.37e-03	66	47	3	MM14839
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	NCOA2 NCOA1	1.61e-03	18	47	2	M4862
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	NCOA2 NCOA1	1.61e-03	18	47	2	MM15034
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	NCOA2 NCOA1	1.61e-03	18	47	2	M26942
Pathway	REACTOME_METABOLISM_OF_STEROIDS	NCOA2 MTF1 CYP8B1 NCOA1	1.70e-03	154	47	4	M27832
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	NCOA2 NCOA1	1.79e-03	19	47	2	MM14612
Pathway	KEGG_CHRONIC_MYELOID_LEUKEMIA	CRKL STAT5A HDAC2	1.83e-03	73	47	3	M321
Pathway	REACTOME_SIGNALING_BY_NOTCH1	HDAC10 MAML3 HDAC2	1.91e-03	74	47	3	M616
Pathway	BIOCARTA_AMI_PATHWAY	FGB PROS1	1.99e-03	20	47	2	M15394
Pubmed	SRC-1 and TIF2 control energy balance between white and brown adipose tissues.	NCOA2 NCOA1	3.33e-06	2	64	2	12507421
Pubmed	Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or erythropoietin.	CRKL STAT5A	3.33e-06	2	64	2	9837784
Pubmed	Usefulness of measurement of fibrinogen, D-dimer, D-dimer/fibrinogen ratio, C reactive protein and erythrocyte sedimentation rate to assess the pathophysiology and mechanism of ischaemic stroke.	FGB CRP	3.33e-06	2	64	2	21296900
Pubmed	Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.	NCOA2 NCOA1	3.33e-06	2	64	2	15070739
Pubmed	Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.	NCOA2 NCOA1	3.33e-06	2	64	2	11897715
Pubmed	Tumor necrosis factor-alpha suppresses the expression of steroid receptor coactivator-1 and -2: a possible mechanism contributing to changes in steroid hormone responsiveness.	NCOA2 NCOA1	3.33e-06	2	64	2	15231721
Pubmed	Distinct steady-state nuclear receptor coregulator complexes exist in vivo.	NCOA2 NCOA1	3.33e-06	2	64	2	9751728
Pubmed	Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis.	NCOA2 NCOA1	3.33e-06	2	64	2	25148457
Pubmed	NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain.	NCOA1 STAT5A	9.99e-06	3	64	2	12954634
Pubmed	The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.	NCOA2 NCOA1	9.99e-06	3	64	2	21035760
Pubmed	Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.	NCOA2 NCOA1	9.99e-06	3	64	2	24550004
Pubmed	Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.	NCOA2 NCOA1	9.99e-06	3	64	2	21059860
Pubmed	RORgammat recruits steroid receptor coactivators to ensure thymocyte survival.	NCOA2 NCOA1	9.99e-06	3	64	2	16148126
Pubmed	Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse.	NCOA2 NCOA1	9.99e-06	3	64	2	16914740
Pubmed	Clinical implications of adiponectin and inflammatory biomarkers in type 2 diabetes mellitus.	FGB CRP	9.99e-06	3	64	2	20075509
Pubmed	Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.	NCOA2 NCOA1	9.99e-06	3	64	2	16675958
Pubmed	Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.	NCOA2 NCOA1	9.99e-06	3	64	2	9506940
Pubmed	Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.	NCOA2 NCOA1	9.99e-06	3	64	2	28390937
Pubmed	The role of SRC1 and SRC2 in steroid-induced SDF1 expression in normal and ectopic endometrium.	NCOA2 NCOA1	9.99e-06	3	64	2	24586072
Pubmed	Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human.	NCOA2 NCOA1	9.99e-06	3	64	2	17045797
Pubmed	Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.	NCOA2 NCOA1	9.99e-06	3	64	2	23927929
Pubmed	Simple laboratory score improves the preoperative diagnosis of adnexal mass.	FGB CRP	9.99e-06	3	64	2	26499778
Pubmed	Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts.	NCOA2 NCOA1	9.99e-06	3	64	2	33574497
Pubmed	Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.	NCOA2 NCOA1	9.99e-06	3	64	2	18845648
Pubmed	The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.	NCOA2 NCOA1	9.99e-06	3	64	2	12138202
Pubmed	Genetic variation in estrogen receptor, C-reactive protein and fibrinogen does not predict the plasma levels of inflammation markers after longterm hormone replacement therapy.	FGB CRP	9.99e-06	3	64	2	17264952
Pubmed	Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.	NCOA2 NCOA1	9.99e-06	3	64	2	14757047
Pubmed	Structure and chromosomal locations of mouse steroid receptor coactivator gene family.	NCOA2 NCOA1	9.99e-06	3	64	2	10501088
Pubmed	IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.	FGB CRP	9.99e-06	3	64	2	19272152
Pubmed	Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators.	NCOA2 NCOA1	9.99e-06	3	64	2	12114525
Pubmed	Inflammation and chemerin in colorectal cancer.	FGB CRP	9.99e-06	3	64	2	26628300
Pubmed	Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.	NCOA2 NCOA1	9.99e-06	3	64	2	15983373
Pubmed	The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.	NCOA2 NCOA1	9.99e-06	3	64	2	16423883
Pubmed	miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.	NCOA2 NCOA1	2.00e-05	4	64	2	26066330
Pubmed	Diagnostic accuracy of fibrinogen to differentiate appendicitis from nonspecific abdominal pain in children.	FGB CRP	2.00e-05	4	64	2	27760719
Pubmed	Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.	NCOA2 NCOA1	2.00e-05	4	64	2	11818499
Pubmed	Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins.	NCOA2 NCOA1	2.00e-05	4	64	2	10454563
Pubmed	P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.	NCOA2 NCOA1	2.00e-05	4	64	2	18267973
Pubmed	Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.	NCOA2 NCOA1	2.00e-05	4	64	2	15331759
Pubmed	Thrombopoietin and interleukin-2 induce association of CRK with STAT5.	CRKL STAT5A	2.00e-05	4	64	2	11097834
Pubmed	Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.	NCOA2 NCOA1	2.00e-05	4	64	2	12024042
Pubmed	Isolation and characterization of a novel class II histone deacetylase, HDAC10.	HDAC10 HDAC2	2.00e-05	4	64	2	11739383
Pubmed	Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells.	NCOA2 NCOA1	2.00e-05	4	64	2	17513608
Pubmed	Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome.	OTC GLA	2.00e-05	4	64	2	2890215
Pubmed	Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.	NCOA2 NCOA1	2.00e-05	4	64	2	19095746
Pubmed	Erythropoietin induces tyrosine phosphorylation of Jak2, STAT5A, and STAT5B in primary cultured human erythroid precursors.	CRKL STAT5A	2.00e-05	4	64	2	9657743
Pubmed	Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?	FGB CRP	2.00e-05	4	64	2	27044366
Pubmed	Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha.	NCOA2 NCOA1	2.00e-05	4	64	2	10594042
Pubmed	Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-alpha depends on the coactivator subtype, the type of estrogen response element, and the promoter context.	NCOA2 NCOA1	2.00e-05	4	64	2	12403846
Pubmed	Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.	NCOA2 NCOA1	2.00e-05	4	64	2	22560224
Pubmed	A simple method to screen ligands of peroxisome proliferator-activated receptor delta.	NCOA2 NCOA1	2.00e-05	4	64	2	16930961
Pubmed	Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.	NCOA2 NCOA1	2.00e-05	4	64	2	26267537
Pubmed	Isoform-specific transcriptional regulation by thyroid hormone receptors: hormone-independent activation operates through a steroid receptor mode of co-activator interaction.	NCOA2 NCOA1	2.00e-05	4	64	2	11435616
Pubmed	Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10.	HDAC10 HDAC2	2.00e-05	4	64	2	35143520
Pubmed	Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.	NCOA2 NCOA1	2.00e-05	4	64	2	15563453
Pubmed	Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene.	NCOA2 NCOA1	3.32e-05	5	64	2	10652338
Pubmed	Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members.	NCOA2 NCOA1	3.32e-05	5	64	2	17950690
Pubmed	SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.	NCOA2 NCOA1	3.32e-05	5	64	2	17476305
Pubmed	Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.	NCOA2 NCOA1	3.32e-05	5	64	2	17854779
Pubmed	Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes.	NCOA2 NCOA1	3.32e-05	5	64	2	18511550
Pubmed	Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription.	NCOA2 NCOA1	3.32e-05	5	64	2	11514567
Pubmed	Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.	NCOA2 NCOA1	3.32e-05	5	64	2	11014206
Pubmed	Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.	NCOA2 NCOA1	3.32e-05	5	64	2	14993927
Pubmed	Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.	NCOA2 NCOA1	3.32e-05	5	64	2	12714702
Pubmed	Regulation of transcription by a protein methyltransferase.	NCOA2 NCOA1	3.32e-05	5	64	2	10381882
Pubmed	Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1.	NCOA2 NCOA1	3.32e-05	5	64	2	15721253
Pubmed	SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.	NCOA2 NCOA1	3.32e-05	5	64	2	12514218
Pubmed	Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.	NCOA2 NCOA1	3.32e-05	5	64	2	11376110
Pubmed	Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.	NCOA2 NCOA1	3.32e-05	5	64	2	18798693
Pubmed	Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.	NCOA2 NCOA1	3.32e-05	5	64	2	12554772
Pubmed	RBCK1, an E3 ubiquitin ligase, interacts with and ubiquinates the human pregnane X receptor.	NCOA2 NCOA1	3.32e-05	5	64	2	23160820
Pubmed	SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.	NCOA2 NCOA1	3.32e-05	5	64	2	9812974
Pubmed	A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.	NCOA2 NCOA1	3.32e-05	5	64	2	15026545
Pubmed	The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding.	NCOA2 NCOA1	3.32e-05	5	64	2	10757795
Pubmed	2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.	NCOA2 NCOA1	3.32e-05	5	64	2	12796488
Pubmed	MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions.	BLOC1S1 HDAC2	3.32e-05	5	64	2	12639951
Pubmed	Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status.	NCOA2 NCOA1	3.32e-05	5	64	2	10803578
Pubmed	Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.	CRKL STAT5A	4.98e-05	6	64	2	11167825
Pubmed	A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.	NCOA2 NCOA1	4.98e-05	6	64	2	16373399
Pubmed	Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines.	NCOA2 NCOA1	4.98e-05	6	64	2	12630920
Pubmed	Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells.	NCOA2 NCOA1	4.98e-05	6	64	2	16728408
Pubmed	Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.	NCOA2 NCOA1	4.98e-05	6	64	2	24811170
Pubmed	Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.	NCOA2 NCOA1	4.98e-05	6	64	2	16923966
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	NCOA2 TIA1 NCOA1	6.96e-05	43	64	3	26487511
Pubmed	Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.	NCOA2 NCOA1	6.96e-05	7	64	2	21195347
Pubmed	BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.	NCOA2 NCOA1	6.96e-05	7	64	2	16860316
Pubmed	The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.	NCOA2 NCOA1	6.96e-05	7	64	2	9192892
Pubmed	Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells.	NCOA2 NCOA1	6.96e-05	7	64	2	11117530
Pubmed	Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome.	CRKL HIRA	6.96e-05	7	64	2	11242111
Pubmed	Comparison of the physical and recombination maps of the mouse X chromosome.	OTC GLA	6.96e-05	7	64	2	2571569
Pubmed	Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.	NCOA2 NCOA1	6.96e-05	7	64	2	21478865
Pubmed	Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.	NCOA2 NCOA1	6.96e-05	7	64	2	9590696
Pubmed	Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions.	NCOA2 NCOA1	6.96e-05	7	64	2	15641800
Pubmed	Efficient linkage of 10 loci in the proximal region of the mouse X chromosome.	OTC GLA	6.96e-05	7	64	2	2110546
Pubmed	The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.	NCOA2 NCOA1	6.96e-05	7	64	2	12709428
Pubmed	Polycomb subunit BMI1 determines uterine progesterone responsiveness essential for normal embryo implantation.	NCOA2 NCOA1	6.96e-05	7	64	2	29202468
Pubmed	The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.	NCOA2 NCOA1	9.27e-05	8	64	2	12082103
Pubmed	Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities.	NCOA2 NCOA1	9.27e-05	8	64	2	11050077
Pubmed	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.	NCOA2 NCOA1	9.27e-05	8	64	2	11971985
Pubmed	Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes.	NCOA2 NCOA1	9.27e-05	8	64	2	12145209
Cytoband	4q28	FGB MAML3	6.84e-05	9	64	2	4q28
Cytoband	1p22.3	CLCA1 DNAI3	4.34e-04	22	64	2	1p22.3
Cytoband	18q23	TXNL4A RBFA	7.58e-04	29	64	2	18q23
Cytoband	Ensembl 112 genes in cytogenetic band chr18q23	TXNL4A RBFA	1.44e-03	40	64	2	chr18q23
GeneFamily	WD repeat domain containing	WDR97 KIF21A TLE6 DNAI3 WDSUB1 HIRA	8.14e-05	262	50	6	362
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA2 NCOA1	9.93e-04	17	50	2	486
GeneFamily	EF-hand domain containing	CRNN NINL PLCD1 RCN3	3.12e-03	219	50	4	863
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	KCNT2 KIF21A EPB41L5 NINL FHOD3 MAML3	3.44e-05	204	64	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4	KCNT2 KIF21A EPB41L5 NINL MAML3	3.62e-05	124	64	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TMPRSS9 CYP8B1 FGB CTSE RHCE CRP	2.92e-07	187	64	6	edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TMPRSS9 CYP8B1 FGB CTSE RHCE CRP	3.11e-07	189	64	6	7899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TMPRSS9 CYP8B1 FGB CTSE RHCE CRP	3.21e-07	190	64	6	a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SYT16 RTKN2 KCNT2 EPB41L5 CTSE	5.94e-06	179	64	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMPRSS9 GALNT17 ABCA6 FHOD3 DNAI3	6.11e-06	180	64	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMPRSS9 GALNT17 ABCA6 FHOD3 DNAI3	6.11e-06	180	64	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 NCOA2 EPB41L5 NCOA1 MAML3	9.69e-06	198	64	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNT2 ABCA6 PLEKHA4 ADAMTSL2 PROS1	9.93e-06	199	64	5	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNT2 ABCA6 PLEKHA4 ADAMTSL2 PROS1	9.93e-06	199	64	5	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TMPRSS9 MYO7A DNAI3 RHCE	4.67e-05	138	64	4	2709fb83dfe6c2e27050b08b678a6d6b25d47906
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	5.97e-05	147	64	4	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	6.62e-05	151	64	4	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	droplet-Liver-nan-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	6.62e-05	151	64	4	7758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCell	droplet-Liver-nan-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	6.62e-05	151	64	4	b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCell	droplet-Liver-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	6.80e-05	152	64	4	1febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCell	droplet-Liver-nan-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTC CYP8B1 FGB CRP	6.80e-05	152	64	4	faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12B KIF21A FGB TLE6	6.80e-05	152	64	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12B KIF21A FGB TLE6	6.80e-05	152	64	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYT16 RTKN2 CTSE	8.87e-05	60	64	3	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYT16 RTKN2 CTSE	8.87e-05	60	64	3	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	GALNT17 KCNT2 ABCA6 ADAMTSL2	9.78e-05	167	64	4	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA1 RCN3 RASAL1 RHCE	1.12e-04	173	64	4	e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	OTC CYP8B1 FGB CRP	1.15e-04	174	64	4	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	KCNT2 CYP8B1 FGB CRP	1.15e-04	174	64	4	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 TRPM7 PRRC2C ADAMTSL2	1.20e-04	176	64	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KCNT2 CYP8B1 FGB CRP	1.20e-04	176	64	4	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	RTKN2 KCNT2 EPB41L5 CTSE	1.31e-04	180	64	4	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMPRSS9 ABCA6 FHOD3 DNAI3	1.33e-04	181	64	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	TXNRD1 KCNT2 ABCA6 ADAMTSL2	1.33e-04	181	64	4	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	RTKN2 KCNT2 EPB41L5 CTSE	1.36e-04	182	64	4	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTKN2 GPR50 CTSE DNAH8	1.36e-04	182	64	4	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	IPF-Epithelial-ATI\|World / Disease state, Lineage and Cell class	RTKN2 KCNT2 EPB41L5 CTSE	1.39e-04	183	64	4	31fef35ecf30162662f24d335d8f0cceacc07039
ToppCell	COVID-19-lung-Epithelial\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RTKN2 TIA1 BLOC1S1 CTSE	1.39e-04	183	64	4	3a5d00006a195b5a5c27e7ace615e5de73145e97
ToppCell	IPF-Epithelial-ATI\|IPF / Disease state, Lineage and Cell class	RTKN2 KCNT2 EPB41L5 CTSE	1.39e-04	183	64	4	c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	RUSC1 RASAL1 HDAC2 PROS1	1.42e-04	184	64	4	030d5ef5e44e4d973862128fe01f7e8ef0092a06
ToppCell	IPF-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	RTKN2 KCNT2 EPB41L5 CTSE	1.48e-04	186	64	4	d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCell	Control-Epithelial-ATI\|Control / Disease state, Lineage and Cell class	RTKN2 KCNT2 EPB41L5 CTSE	1.51e-04	187	64	4	fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	GALNT17 TRPM7 KIF21A FHOD3	1.51e-04	187	64	4	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	ASK454-Epithelial-Type_1\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	RTKN2 KCNT2 EPB41L5 CTSE	1.54e-04	188	64	4	13f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCell	15-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	OTC FGB CTSE RHCE	1.54e-04	188	64	4	c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell	15-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	OTC FGB CTSE RHCE	1.54e-04	188	64	4	2534684e4932c1255c24a26ca2277ac7af0a118b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNT2 ABCA6 DNAH8 ADAMTSL2	1.57e-04	189	64	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNT2 ABCA6 DNAH8 ADAMTSL2	1.57e-04	189	64	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	GALNT17 TRPM7 KIF21A FHOD3	1.57e-04	189	64	4	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMPRSS9 CLCA1 KCNE1	1.59e-04	73	64	3	51bcbb57ee6c45cad88cb3e2cedab2cf3503b2a5
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	NCOA2 RTKN2 EPSTI1 DNAH8	1.64e-04	191	64	4	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	LAM-Epithelial-AT1\|LAM / Condition, Lineage and Cell class	RTKN2 KCNT2 EPB41L5 CTSE	1.64e-04	191	64	4	66875b2ec2c510489407f3e433a90cdf74a15094
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GALNT17 KCNT2 ABCA6 RCN3	1.67e-04	192	64	4	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	GALNT17 TRPM7 KIF21A FHOD3	1.67e-04	192	64	4	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TXNRD1 TANC2 NCOA2 MAML3	1.71e-04	193	64	4	779276e775cb2492e8dd36436295a536084a6415
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 ABCA6 RCN3 ADAMTSL2	1.74e-04	194	64	4	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 SYT16 RTKN2 RASAL1	1.74e-04	194	64	4	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 ABCA6 RCN3 ADAMTSL2	1.74e-04	194	64	4	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 SYT16 RTKN2 RASAL1	1.74e-04	194	64	4	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	facs-Heart-RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 ABCA6 RCN3 ADAMTSL2	1.74e-04	194	64	4	c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PRRC2C MAML3 PROS1	1.77e-04	195	64	4	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.77e-04	195	64	4	68f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	RTKN2 KCNT2 EPB41L5 CTSE	1.77e-04	195	64	4	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.77e-04	195	64	4	2a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 NCOA2 NCOA1 MAML3	1.81e-04	196	64	4	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.81e-04	196	64	4	eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SYT16 RTKN2 EPB41L5 CTSE	1.81e-04	196	64	4	150554fa06868d29b0608189862eef6505ba757f
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	TXNRD1 KCNT2 ABCA6 ADAMTSL2	1.81e-04	196	64	4	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.84e-04	197	64	4	c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.84e-04	197	64	4	734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell	ASK440-Epithelial-Type_1\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	RTKN2 KCNT2 EPB41L5 CTSE	1.84e-04	197	64	4	1eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCell	ASK428-Epithelial-Type_1\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	RTKN2 KCNT2 EPB41L5 CTSE	1.84e-04	197	64	4	9ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RTKN2 KCNT2 EPB41L5 CTSE	1.84e-04	197	64	4	e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCell	Biopsy_IPF-Epithelial-AT1\|Biopsy_IPF / Sample group, Lineage and Cell type	RTKN2 KCNT2 EPB41L5 CTSE	1.88e-04	198	64	4	75bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FHOD3 RCN3 ADAMTSL2 PROS1	1.88e-04	198	64	4	63f7d25201613bd3404c28fb936954190bca91d3
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FHOD3 RCN3 ADAMTSL2 PROS1	1.88e-04	198	64	4	a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FHOD3 RCN3 ADAMTSL2 PROS1	1.88e-04	198	64	4	d1e1bdd36c84e1bac21ba137f018defe98456a8c
ToppCell	ASK428-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RTKN2 KCNT2 EPB41L5 CTSE	1.88e-04	198	64	4	0047a9ef7684230ac5179efea94461480e90bdaf
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYT16 RTKN2 EPB41L5 CTSE	1.92e-04	199	64	4	f8846446ebbc4948cdc69640782db1358bbdc486
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SYT16 RTKN2 EPB41L5 CTSE	1.92e-04	199	64	4	fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYT16 RTKN2 EPB41L5 CTSE	1.92e-04	199	64	4	3e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCell	background-Hepatocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	CYP8B1 FGB CRP PROS1	1.95e-04	200	64	4	423cca10df6ae0489a8fe7e7df87e70364dac022
Disease	colon carcinoma (is_marker_for)	IGF2R CRKL	3.34e-04	13	62	2	DOID:1520 (is_marker_for)
Disease	breast carcinoma (is_marker_for)	IGF2R NCOA1 CRP	3.68e-04	66	62	3	DOID:3459 (is_marker_for)
Disease	DiGeorge Syndrome	CRKL HIRA	5.11e-04	16	62	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	CRKL HIRA	5.11e-04	16	62	2	C0795907
Disease	Shprintzen syndrome	CRKL HIRA	5.11e-04	16	62	2	C0220704
Disease	Nephritis, Tubulointerstitial	GLA CRP	8.89e-04	21	62	2	C0041349
Disease	hypertrophic cardiomyopathy	TXNRD1 FHOD3 TNKS1BP1	9.71e-04	92	62	3	EFO_0000538
Disease	Degenerative polyarthritis	TXNRD1 PLCD1 RCN3	1.00e-03	93	62	3	C0029408
Disease	Osteoarthrosis Deformans	TXNRD1 PLCD1 RCN3	1.00e-03	93	62	3	C0086743
Disease	prostate carcinoma (is_marker_for)	CRKL HDAC2	1.07e-03	23	62	2	DOID:10286 (is_marker_for)
Disease	Nephritis, Interstitial	GLA CRP	1.16e-03	24	62	2	C0027707
Disease	remnant cholesterol measurement	IGF2R ABCA6 RHCE	1.54e-03	108	62	3	EFO_0010815
Disease	Epilepsy	TXNRD1 TANC2 KCNT2	1.58e-03	109	62	3	C0014544
Disease	hearing threshold measurement	SLC32A1 GALNT17	1.59e-03	28	62	2	EFO_0007618
Disease	free cholesterol measurement	IGF2R ABCA6 RHCE	1.75e-03	113	62	3	EFO_0008591

Protein segments in the cluster

Peptide	Gene	Start	Entry
QMVIGLSENQGIATW	DMAC1	86	Q96GE9
QTGQWIGMVENFNQA	BLOC1S1	101	P78537
TGIDPTGQQQMWQAI	ABCA6	1441	Q8N139
DMLVIGNFGLSWNQQ	GLA	266	P06280
GNFGLSWNQQVTQMA	GLA	271	P06280
NIIAGGCINGQIVMW	DNAI3	411	Q8IWG1
GQRLVTWNNMVKNTG	DISP1	231	Q96F81
GLVWQGQVAELTTQM	RBFA	261	Q8N0V3
EILGNWNMFVGSQAT	RCN3	301	Q96D15
MQGSEQQWIEFGGNA	RBM12B	226	Q8IXT5
NLGQQLGQGKELWMA	RASAL1	511	O95294
VTMLQNISDNWLGGA	QRFPR	101	Q96P65
SLMGTVQQGAQSWQQ	MAML3	951	Q96JK9
QVDGQWLMVTGQQQL	HSPB9	71	Q9BQS6
IGGWDLSQLQCQMVG	GPR50	91	Q13585
WQIALDNIQVGGTVM	CTSE	256	P14091
LEQSGGCWNMNSGNS	EPSTI1	301	Q96J88
DMNTENGGWTVIQNR	FGB	271	P02675
GGNVLITDTWISMGQ	OTC	256	P00480
MQQGGWVLLQNCHLG	DNAH8	3956	Q96JB1
VEQNWATLQGGEMTI	NRF1	356	Q16656
TNQGLNVMVWNQNGK	ADAMTSL2	306	Q86TH1
RGQEGQQSPEQWQKM	KCNT2	466	Q6UVM3
VTRMNINGQWEGEVN	CRKL	266	P46109
QTQTQPGSGQRWMQV	CRNN	376	Q9UBG3
EMWNGGCQIVALNFQ	PLCD1	566	P51178
QSNGSQQAWGMRSAL	EPB41L5	401	Q9HCM4
GFTVNLPWNQVGMGN	HDAC10	221	Q969S8
GMNGVINRNETIQWL	FHOD3	181	Q2V2M9
GSQSLVGDIGNVNMW	CRP	166	P02741
RWNFIQNGAIMNKGT	GALNT17	551	Q6IS24
LWQETVQQGGNMSGL	KCNE1	16	P15382
GGQGQDSGKVVIWNM	HIRA	31	P54198
VGFMQWDNNGNTGNA	FAM111B	461	Q6SJ93
NRQQTDMAVNWAGGL	HDAC2	126	Q92769
LTKLWQETVQQGGNM	KCNE1B	16	A0A087WTH5
QEKEGISNWLGNMLQ	CYP8B1	246	Q9UNU6
SIMAGSWGGLNQTQL	MT-ND2	161	P03891
EGNSWNLGVVQMSPQ	IGF2R	1146	P11717
QRLWMAEAQSGTGQL	RUSC1	466	Q9BVN2
GFLNQQQMVEGLISW	RTKN2	291	Q8IZC4
MIGWIALGQNSSGEE	SYT16	606	Q17RD7
QQQLWMVEDTLAGLG	PLEKHA4	481	Q9H4M7
VMGEQNLQWILNGAT	MTF1	566	Q14872
DMKAWQQGAIGNNNV	NCOA1	1281	Q15788
WASNKQGGQGDGIQV	PRRC2C	121	Q9Y520
LGTSQIGMSQPGTWQ	SATL1	161	Q86VE3
IGMSQPGTWQTGLSQ	SATL1	166	Q86VE3
IQCDWTMAGQQQGVF	TANC2	971	Q9HCD6
QVLAMWTQEGIQNGR	NINL	326	Q9Y2I6
ITTGGDVINNGLWNM	PROS1	371	P07225
MAGWIQAQQLQGDAL	STAT5A	1	P42229
SKGLTLQNSQWMNGT	CLCA1	491	A8K7I4
SDINGWAQGNMGGNS	NCOA2	1351	Q15596
MIEAVQNHIGSLNWG	TXNRD1	251	Q16881
TVWNGNGMIGFQVLL	RHCE	351	P18577
VWNLVTGQEIMSLGG	KIF21A	1371	Q7Z4S6
MQSGRGSQQWSAGTL	WDR97	881	A6NE52
VGQMDWGNNLGLRDL	TNKS1BP1	1306	Q9C0C2
CMISGWGNTQEGNAT	TMPRSS9	626	Q7Z410
AGWNVTNAIQGMFVL	SLC32A1	121	Q9H598
KVFIWNNMGSQGIQE	ZBTB10	556	Q96DT7
MIDLGTGNNNKINWA	TXNL4A	91	P83876
GTTVLWNTENGQMLA	WDSUB1	76	Q8N9V3
NKWDAENAIQQMGGQ	TIA1	156	P31483
ENAIQQMGGQWLGGR	TIA1	161	P31483
GQQWLVGSLEQAMLD	TRPM7	431	Q96QT4
LLGMANGQQWLQSTS	TLE6	476	Q9H808
EQVMNSGWANGINER	MYO7A	1641	Q13402