Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	abnormal circulating apolipoprotein level	TM6SF2 OSBPL8	1.01e-05	6	12	2	MP:0010332
MousePheno	abnormal apolipoprotein level	TM6SF2 OSBPL8	1.89e-05	8	12	2	MP:0010331
Domain	F-box	FBXO4 FBXO9	2.08e-03	67	19	2	PF00646
Domain	FBOX	FBXO4 FBXO9	2.40e-03	72	19	2	PS50181
Domain	F-box_dom	FBXO4 FBXO9	2.60e-03	75	19	2	IPR001810
Domain	PH	OSBPL8 CDC42BPA	2.23e-02	229	19	2	PF00169
Pubmed	Targeting peroxisome proliferator-activated receptor γ proteasomal degradation by magnolol is a potential avenue for adipogenesis-mediated metabolic homeostasis.	FBXO4 FBXO9	1.55e-05	11	19	2	37203337
Pubmed	Identification of a family of human F-box proteins.	FBXO4 FBXO9	1.86e-04	37	19	2	10531035
Pubmed	A family of mammalian F-box proteins.	FBXO4 FBXO9	2.40e-04	42	19	2	10531037
Pubmed	Defining the membrane proteome of NK cells.	OSBPL8 ARFGEF2 GUSB AQR LGALS8	3.32e-04	1168	19	5	19946888
Pubmed	Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.	FBXO4 FBXO9	4.13e-04	55	19	2	37028429
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXO4 FBXO9	5.08e-04	61	19	2	15520277
Pubmed	Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases.	FBXO4 FBXO9	5.24e-04	62	19	2	29103612
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	TM6SF2 USP38	5.41e-04	63	19	2	11572484
GeneFamily	Cyclins\|F-boxes other	FBXO4 FBXO9	3.48e-04	39	13	2	560
Drug	CAS 79350-37-1	GUSB CPSF4	1.96e-04	25	19	2	CID000002675
Drug	potassium tellurite	GUSB CPSF4	3.64e-04	34	19	2	CID000065186
Drug	Pyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; HL60; HT_HG-U133A	TLCD3A AQR LGALS8	4.36e-04	181	19	3	2957_DN
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	CDC42BPA FBXO9 LGALS8	4.43e-04	182	19	3	1661_UP
Drug	Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	AQR FBXO9 LGALS8	5.42e-04	195	19	3	3519_DN
Drug	Erythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A	AQR CDC42BPA FBXO9	5.42e-04	195	19	3	5329_DN
Drug	Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A	AQR CDC42BPA FBXO9	5.50e-04	196	19	3	1495_UP
Drug	estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A	ARFGEF2 CDC42BPA FBXO9	5.58e-04	197	19	3	1182_UP
Drug	Thiamphenicol [15318-45-3]; Down 200; 11.2uM; PC3; HT_HG-U133A	ARFGEF2 CDC42BPA LGALS8	5.66e-04	198	19	3	1826_DN
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A	CDC42BPA FBXO9 LGALS8	5.66e-04	198	19	3	3754_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	ARFGEF2 CDC42BPA LGALS8	5.66e-04	198	19	3	7003_DN
Drug	Ricinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A	ARFGEF2 CDC42BPA FBXO9	5.66e-04	198	19	3	6206_UP
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ARFGEF2 CPSF4 LGALS8	5.75e-04	199	19	3	7418_UP
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	TLCD3A AQR CDC42BPA	5.75e-04	199	19	3	5353_DN
Drug	FK-506; Down 200; 1uM; MCF7; HG-U133A	CDC42BPA FBXO9 LGALS8	5.75e-04	199	19	3	284_DN
Drug	methoxyamine	GUSB UROC1	6.68e-04	46	19	2	CID000004113
Drug	naringine	GUSB CPSF4	6.68e-04	46	19	2	CID000004441
Drug	imidazole-4-acetic acid	GUSB UROC1	7.27e-04	48	19	2	CID000096215

Protein segments in the cluster

Peptide	Gene	Start	Entry
PYFMMHCHYQGYAAE	ADAM18	86	Q9Y3Q7
FFDYMAVYRMCCPYT	FBXO4	136	Q9UKT5
HASMYYPYLCEIMQF	ARFGEF2	1731	Q9Y6D5
YVVALFMYMCLLGYP	AQR	1206	O60306
YYYVVHPMRYEVRMT	GPR61	141	Q9BZJ8
FSPGMYFEMIIYCDV	LGALS8	261	O00214
TMPFCYRMYFGEHLS	KIAA1109	2456	Q2LD37
HKNMGYYDYISPRFM	OGDHL	946	Q9ULD0
FYGAAVFMYMVPCAY	OR2Z1	251	Q8NG97
YVMTMPYAHCKGILY	OSBPL8	566	Q9BZF1
YYRYIRFFPDGHVMM	FBXO9	296	Q9UK97
YPYAEEVMQMCDRYG	GUSB	386	P08236
HEYDMTKMPECYFYS	CPSF4	86	O95639
MFICAYLPDLMYLDY	DRC3	176	Q9H069
AVMAYDRYMAICYPL	OR6A2	121	O95222
CMYEMLYGETPFYAE	CDC42BPA	271	Q5VT25
YGHIYMYRFCPDIEM	UROC1	71	Q96N76
IPYMIYDSYAMYLCE	TLCD3A	81	Q8TBR7
IHCMMYHYSGFPDLY	USP38	381	Q8NB14
MYMFYVLPFCGLAAY	TM6SF2	271	Q9BZW4