Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainZnf_C2H2-like

BNC2 ZNF346 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZMAT4 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

7.57e-0979612122IPR015880
DomainZnf_C2H2

BNC2 ZNF346 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZMAT4 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

9.28e-0980512122IPR007087
DomainZnF_C2H2

BNC2 ZNF346 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZMAT4 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

9.92e-0980812122SM00355
Domain-

ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

7.48e-08679121193.30.160.60
Domainzf-C2H2

BNC2 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

1.03e-0769312119PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

1.05e-0769412119IPR013087
DomainZINC_FINGER_C2H2_2

BNC2 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

1.22e-0777512120PS50157
DomainZINC_FINGER_C2H2_1

BNC2 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 PRDM13 ZNF740 ZNF653 ZNF433

1.27e-0777712120PS00028
DomainCNH

TNIK MINK1 MAP4K4

9.16e-05141213SM00036
DomainCNH

TNIK MINK1 MAP4K4

1.14e-04151213PF00780
DomainCNH

TNIK MINK1 MAP4K4

1.14e-04151213PS50219
DomainCNH_dom

TNIK MINK1 MAP4K4

1.14e-04151213IPR001180
DomainPH_BEACH

NBEA LYST

6.14e-0461212PF14844
DomainDH_1

TRIO ARHGEF18 ARHGEF25 SOS2

7.43e-04631214PS00741
DomainKinase-like_dom

TNIK TRIO MINK1 CHD9 CDC7 STK3 JAK2 CLK3 PRKCE KIT MAP4K4

7.98e-0454212111IPR011009
DomainPROTEIN_KINASE_ATP

TNIK TRIO MINK1 CDC7 STK3 JAK2 CLK3 PRKCE KIT MAP4K4

8.11e-0445912110PS00107
DomainProtein_kinase_ATP_BS

TNIK MINK1 CDC7 STK3 JAK2 CLK3 PRKCE KIT MAP4K4

8.14e-043791219IPR017441
DomainZnf_U1

ZNF346 ZMAT4 ZFHX2

8.57e-04291213IPR003604
DomainZnF_U1

ZNF346 ZMAT4 ZFHX2

8.57e-04291213SM00451
DomainRhoGEF

TRIO ARHGEF18 ARHGEF25 SOS2

9.91e-04681214SM00325
DomainRhoGEF

TRIO ARHGEF18 ARHGEF25 SOS2

1.11e-03701214PF00621
DomainDH_2

TRIO ARHGEF18 ARHGEF25 SOS2

1.11e-03701214PS50010
DomainPH-BEACH_dom

NBEA LYST

1.14e-0381212IPR023362
Domain-

NBEA LYST

1.14e-03812122.30.29.40
DomainPH_BEACH

NBEA LYST

1.14e-0381212PS51783
Domain-

TRIO ARHGEF18 ARHGEF25 SOS2

1.17e-037112141.20.900.10
DomainDH-domain

TRIO ARHGEF18 ARHGEF25 SOS2

1.17e-03711214IPR000219
DomainProt_kinase_dom

TNIK TRIO MINK1 CDC7 STK3 JAK2 CLK3 PRKCE KIT MAP4K4

1.31e-0348912110IPR000719
DomainPROTEIN_KINASE_DOM

TNIK TRIO MINK1 CDC7 STK3 JAK2 CLK3 PRKCE KIT MAP4K4

1.39e-0349312110PS50011
DomainBEACH

NBEA LYST

1.45e-0391212PS50197
DomainBeach

NBEA LYST

1.45e-0391212PF02138
Domain-

NBEA LYST

1.45e-03912121.10.1540.10
DomainBeach

NBEA LYST

1.45e-0391212SM01026
DomainBEACH_dom

NBEA LYST

1.45e-0391212IPR000409
DomainDHR-1_domain

DOCK3 DOCK11

2.20e-03111212IPR027007
DomainDHR_2

DOCK3 DOCK11

2.20e-03111212PS51651
DomainDHR_1

DOCK3 DOCK11

2.20e-03111212PS51650
DomainDHR-2

DOCK3 DOCK11

2.20e-03111212PF06920
DomainDOCK

DOCK3 DOCK11

2.20e-03111212IPR026791
DomainDOCK_C

DOCK3 DOCK11

2.20e-03111212IPR010703
DomainDOCK-C2

DOCK3 DOCK11

2.20e-03111212PF14429
DomainDHR-2

DOCK3 DOCK11

2.20e-03111212IPR027357
DomainSer/Thr_kinase_AS

TNIK TRIO MINK1 CDC7 STK3 CLK3 PRKCE MAP4K4

2.28e-033571218IPR008271
DomainS_TKc

TNIK TRIO MINK1 CDC7 STK3 CLK3 PRKCE MAP4K4

2.36e-033591218SM00220
DomainPROTEIN_KINASE_ST

TNIK TRIO MINK1 CDC7 STK3 CLK3 PRKCE MAP4K4

2.48e-033621218PS00108
DomainPkinase

TNIK TRIO MINK1 CDC7 STK3 CLK3 PRKCE MAP4K4

3.39e-033811218PF00069
DomainLRRNT

LRRC4B LINGO2 LRRC4

4.91e-03531213PF01462
DomainZF_MATRIN

ZNF346 ZMAT4

5.95e-03181212PS50171
PathwayWP_HIPPOYAP_SIGNALING

TNIK MINK1 TEAD4 STK3 MAP4K4

1.93e-0722875M39821
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK TRIO GIT1 DOCK11 SYNE1 MINK1 ARHGEF18 NBEA ADAM22 ZNF462 FRY TRIM28 NAV1 GOLGA8B PRKCE PIP4K2C MAP4K4 PCNT

1.02e-089631241828671696
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 USP13 ABCA2 ZNF234 TRIO GIT1 SYNE1 ZNF423 TTLL5 CHD9 NBEA LRRC4 TUBGCP5 ADAM22 BRWD3 ZBTB44 FRY MAP4K4 PCNT SOS2

3.02e-0812851242035914814
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

TNIK TRIO GIT1 SYNE1 PCLO MINK1 ARHGEF18 NBEA ADAM22 PRKCE

7.34e-082811241028706196
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TNIK TRIO GIT1 SYNE1 MINK1 NBEA ADAM22 PRKCE

3.52e-06251124827507650
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

BNC2 ZNF423 MINK1 USP46 JMJD1C ZNF462 VPS13D UGCG USP12 ATP11A MAP4K4

3.71e-065361241115840001
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TRIO MINK1 ARHGEF18 CHD9 CHST11 CPT1A JMJD1C BRWD3 RLF ZNF462 JAK2 NAV1 ZFHX2 PRKCE ATP11A PCNT PDZD2 SOS2

5.82e-0614891241828611215
Pubmed

c-kit delineates a distinct domain of progenitors in the developing kidney.

SFRP1 WT1 KIT

7.15e-0611124316942767
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

TBX4 SYNE1 ZNF740 NUP188 PDZD2

8.55e-0677124524927568
Pubmed

Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms.

JAK2 BRCA1

1.26e-052124238139386
Pubmed

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

BRCA1 KIT

1.26e-052124221765473
Pubmed

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

WT1 KIT

1.26e-05212428382938
Pubmed

Molecular analysis of WT1 and KIT mutations in patients from an Indian population with de novo acute myeloid leukemia: determination of incidence, distribution patterns, and report of a novel KIT mutation.

WT1 KIT

1.26e-052124221504297
Pubmed

The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth.

USP46 USP12

1.26e-052124225855980
Pubmed

Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD816V and JAK2V617F.

JAK2 KIT

1.26e-052124218165278
Pubmed

[Analysis of c-kit and JAK2 gene mutations in t(8;21) acute myeloid leukemia].

JAK2 KIT

1.26e-052124219176031
Pubmed

KIT D816V and JAK2 V617F mutations are seen recurrently in hypereosinophilia of unknown significance.

JAK2 KIT

1.26e-052124226017288
Pubmed

Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice.

JAK2 KIT

1.26e-052124224211109
Pubmed

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

BRCA1 KIT

1.26e-052124221132007
Pubmed

JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor.

JAK2 KIT

1.26e-05212428611693
Pubmed

Adult-onset systemic mastocytosis in monozygotic twins with KIT D816V and JAK2 V617F mutations.

JAK2 KIT

1.26e-052124222608575
Pubmed

Clinical and histopathological features of myeloid neoplasms with concurrent Janus kinase 2 (JAK2) V617F and KIT proto-oncogene, receptor tyrosine kinase (KIT) D816V mutations.

JAK2 KIT

1.26e-052124234060083
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK DOCK3 TRIO GIT1 PCLO MINK1 LRRC4B NBEA ADAM22 TRIM28 XRN1 NAV1 UBR3 MAP4K4 GABRA5

1.39e-0511391241536417873
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO TTLL5 CHD9 NBEA NWD2

1.55e-0587124512465718
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

TNIK MINK1 MAP4K4

1.95e-0515124322797597
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

BNC2 ZNF423 MINK1 JMJD1C ZNF462 VPS13D UGCG USP12 ATP11A MAP4K4

2.44e-055381241010512203
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

TNIK BNC2 TRIO ZNF423 ALDH3A2

3.20e-05101124518519826
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

BNC2 ZNF346 ZNF143 TBX4 ZNF423 WT1 ZNF462 ZBTB44 TRIM28 ZNF740 ATF3 ZNF653

3.37e-058081241220412781
Pubmed

Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice.

JMJD1C JAK2

3.77e-053124232017785
Pubmed

Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism.

USP13 CLK3

3.77e-053124232453420
Pubmed

Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer.

BRCA1 TRIM28

3.77e-053124223991171
Pubmed

Expression of the adaptor protein Lnk in leukemia cells.

JAK2 KIT

3.77e-053124219375649
Pubmed

MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.

STK3 FRY

3.77e-053124219327996
Pubmed

[Tyrosine kinase mutation and acute myeloid leukemia with T (8; 21)].

JAK2 KIT

3.77e-053124219698218
Pubmed

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERĪ±-positive breast cancer through regulation of BRCA1.

ZNF423 BRCA1

3.77e-053124228968398
Pubmed

A JAK2-V617F activating mutation in addition to KIT and FLT3 mutations is associated with clinical outcome in patients with t(8;21)(q22;q22) acute myeloid leukemia.

JAK2 KIT

3.77e-053124219181784
Pubmed

Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (Wsh) homozygotes.

LYST KIT

3.77e-05312423910518
Pubmed

Convergence of signaling by interleukin-3, granulocyte-macrophage colony-stimulating factor, and mast cell growth factor on JAK2 tyrosine kinase.

JAK2 KIT

3.77e-05312427527392
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

3.77e-053124218930710
Pubmed

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.

ZNF423 WT1

3.77e-053124228722653
Pubmed

Incidences and Prognostic Impact of c-KIT, WT1, CEBPA, and CBL Mutations, and Mutations Associated With Epigenetic Modification in Core Binding Factor Acute Myeloid Leukemia: A Multicenter Study in a Korean Population.

WT1 KIT

3.77e-053124225932436
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 ABCA2 TRIO SFI1 INO80 LYST JAK2 ZNF276 TRIM28 ZNF335 SNX8 NAV1 NUP188 PCNT

4.17e-0511051241435748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO GIT1 DOCK11 MINK1 LYST STK3 VPS13D CLK3 XRN1 NAV1 PRKCE MAP4K4

6.20e-058611241236931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 ARHGEF18 TUBGCP5 JMJD1C ZNF462 VPS13D LTN1 UBR3 ATP11A

7.22e-05493124915368895
Pubmed

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.

JAK2 BRCA1

7.53e-054124226575024
Pubmed

A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.

USP46 USP12

7.53e-054124227650958
Pubmed

WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.

USP46 USP12

7.53e-054124239432777
Pubmed

Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.

NBEA LYST

7.53e-054124211102458
Pubmed

Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells.

JAK2 BRCA1

7.53e-054124211163768
Pubmed

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus.

USP46 USP12

7.53e-054124230466959
Pubmed

TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates.

WT1 KIT

7.53e-054124222069478
Pubmed

SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms.

JAK2 BRCA1

7.53e-054124217565041
Pubmed

High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes.

WT1 KIT

7.53e-054124220861915
Pubmed

The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase.

USP46 USP12

7.53e-054124233844468
Pubmed

RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner.

BRCA1 TRIM28

7.53e-054124226766492
Pubmed

Monitoring of minimal residual disease in patients with core binding factor acute myeloid leukemia and the impact of C-KIT, FLT3, and JAK2 mutations on clinical outcome.

JAK2 KIT

7.53e-054124219603346
Pubmed

Wilms tumor gene 1 (WT1), TP53, RAS/BRAF and KIT aberrations in testicular germ cell tumors.

WT1 KIT

7.53e-054124227085458
Pubmed

E1-mediated recruitment of a UAF1-USP deubiquitinase complex facilitates human papillomavirus DNA replication.

USP46 USP12

7.53e-054124224850727
Pubmed

Genetic mutations associated with cigarette smoking in pancreatic cancer.

WT1 JAK2 BRCA1 KIT

7.79e-0563124419351817
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

TRIO MINK1 LYST CDC7 STK3 JAK2 TRIM28 CLK3 BOP1 NUP188 PIP4K2C MAP4K4

1.05e-049101241236736316
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

TRIO CPT1A LTN1 XRN1 MAP4K4 PCNT

1.17e-04212124633853758
Pubmed

Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.

BRCA1 LTN1

1.25e-045124227977889
Pubmed

The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.

GIT1 PCLO

1.25e-045124212473661
Pubmed

Activating mutations in human acute megakaryoblastic leukemia.

JAK2 KIT

1.25e-045124218755984
Pubmed

[Expression of cell cycle molecules in human azoospermic testes].

CDC7 CLK3

1.25e-045124219426592
Pubmed

UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

USP46 USP12

1.25e-045124219075014
Pubmed

Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.

JAK2 KIT

1.25e-045124215007095
Pubmed

Dynamic Epicardial Contribution to Cardiac Interstitial c-Kit and Sca1 Cellular Fractions.

WT1 KIT

1.25e-045124235706902
Pubmed

Stat1 associates with c-kit and is activated in response to stem cell factor.

JAK2 KIT

1.25e-04512429355737
Pubmed

Assembly of high order G alpha q-effector complexes with RGS proteins.

TRIO ARHGEF25

1.25e-045124218936096
Pubmed

WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex.

USP46 USP12

1.25e-045124220147737
Pubmed

Characterisation of Crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern.

WT1 KIT

1.25e-045124211084657
Pubmed

Perforin is a critical physiologic regulator of T-cell activation.

UNC13D LYST

1.25e-045124221606480
Pubmed

Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.

TBX4 CKM DUSP26

1.51e-0429124322972626
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CHD9 INO80 TUBGCP5 BRWD3 EDEM3 BRCA1 TRIM28 TNFSF13B LTN1 XRN1 ZNF740 NUP188 PIP4K2C

1.82e-0411161241331753913
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

TNIK DOCK3 NBEA JAK2 BRCA1 SNX8 SOS2

1.86e-04329124717474147
Pubmed

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect.

UNC13D LYST

1.87e-046124238722309
Pubmed

Fatty Acid Synthase-Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD.

TRIM28 SNX8

1.87e-046124234231239
Pubmed

Discrete protein interactions with the Grb2/c-Cbl complex in SCF- and TPO-mediated myeloid cell proliferation.

JAK2 KIT

1.87e-04612428950973
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZBTB6 TBX4 WT1 RLF ZNF462 ZNF276 BRCA1 TRIM28 ZFHX2 BOP1

2.36e-047091241022988430
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

LRRC4B LINGO2 LRRC4

2.44e-0434124318848646
Pubmed

Tumor suppressor gene mutations in mice.

WT1 BRCA1

2.62e-04712428982467
Pubmed

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development.

RLF TRIM28

2.62e-047124219099580
Pubmed

MAP4K4 and WT1 mediate SOX6-induced cellular senescence by synergistically activating the ATF2-TGFĪ²2-Smad2/3 signaling pathway in cervical cancer.

WT1 MAP4K4

2.62e-047124238383842
Pubmed

SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.

TRIM28 PCNT

2.62e-047124220622265
Pubmed

Control of biochemical reactions through supramolecular RING domain self-assembly.

BRCA1 TRIM28

2.62e-047124212438698
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

TRIO NAV1

2.62e-047124225065758
Pubmed

Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response.

JAK2 PRKCE

2.62e-047124220353823
Pubmed

USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.

USP13 BRCA1

2.62e-047124228569838
Pubmed

Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.

JAK2 KIT

2.62e-047124218270328
Pubmed

Linkage of loci associated with two pigment mutations on mouse chromosome 13.

LYST DHFR2

2.62e-04712421682216
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ZNF346 GIT1 DOCK11 MINK1 INO80 STK3 BRCA1 DHFR2 XRN1 BOP1

2.79e-047241241036232890
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TNIK TRIO ARHGEF18 SPG11 JMJD1C EDEM3 XRN1 NAV1 MAP4K4 ITPRIPL1

3.07e-047331241034672954
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TRIO GIT1 DOCK11 INO80 TUBGCP5 FRY NWD2 BOP1

3.16e-04475124831040226
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DOCK11 PCLO NBEA JAK2 ZBTB44 FRY UGCG PRDM13 NUP188 ITPRIPL1

3.17e-047361241029676528
Pubmed

Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.

ADAMTS2 CAPN6 WT1

3.41e-0438124331624071
Pubmed

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

ZNF346 WT1 PCNT

3.41e-0438124311555636
Pubmed

HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.

BRCA1 KIT

3.48e-048124223039116
Pubmed

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.

JAK2 USP12

3.48e-048124219915573
Pubmed

The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair.

USP46 USP12

3.48e-048124227463890
Pubmed

Genetically determined murine models of immunodeficiency.

LYST KIT

3.48e-04812423297105
InteractionAGAP2 interactions

TNIK TRIO GIT1 SYNE1 PCLO MINK1 ARHGEF18 NBEA PRKCE

4.39e-062101199int:AGAP2
InteractionDLGAP1 interactions

TNIK TRIO GIT1 SYNE1 MINK1 NBEA ADAM22 MAP4K4

1.17e-051801198int:DLGAP1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

BNC2 ZNF492 ZBTB6 ZNF143 ZNF234 ZNF423 WT1 ZSCAN25 RLF ZNF462 ZBTB44 ZNF276 ZNF550 ZBTB25 ZNF335 ZFHX2 ZNF740 ZNF653 ZNF433

2.34e-09718911928
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO ARHGEF18 ARHGEF25 SOS2

3.41e-0466914722
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA LYST

8.82e-0499121230
CoexpressionGSE17721_CTRL_VS_CPG_0.5H_BMDC_UP

ZNF346 ARHGEF18 TEAD4 LYST CDC7 JAK2 PRKCE PIP4K2C SOS2

3.80e-071991219M3754
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

DOCK3 TLCD3B PCLO LRRC4B NBEA CHST11 PRAMEF1 LYST ZNF462 DUSP26 FRY TNFSF13B UGCG NAV1 ZFHX2 GOLGA8B CALN1

1.33e-05110612117M39071
CoexpressionGSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

MAN2A1 DOCK11 ARHGEF18 CHD9 FRY CD300LB ITPRIPL1

1.39e-051691217M9087
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL

ABCA2 GIT1 DOCK11 PCLO NBEA LYST DUSP26 NAV1 ZFHX2 PRKCE

3.12e-0542912110M45694
CoexpressionGSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP

SFI1 VPS13D CLK3 ZNF335 UBR3 ATP11A ZNF653

4.11e-052001217M3312
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

BNC2 SFRP1 TRIO ADAMTS2 DOCK11 CAPN6 CHD9 NBEA JMJD1C RLF ZNF462 ACE2 ZBTB44 VPS13D NAV1

2.39e-0579011515gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d8.VSVOva, CD8+ CD45.1+, Spleen, avg-3

TNIK ABCA2 MAN2A1 TRIO GIMAP5 ARHGEF18 LYST UGCG XRN1 ZFHX2

4.91e-0538711510GSM538392_500
CoexpressionAtlasNK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3

TNIK ABCA2 TRIO GIMAP5 ARHGEF18 CHST11 FRY UGCG ZFHX2 SOS2

8.43e-0541311510GSM538303_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

BNC2 SFRP1 TRIO ADAMTS2 DOCK11 ZNF423 NBEA CHST11 USP46 ARHGEF25 LRRC4 ADAM22 ZNF462 SOS2

9.65e-0579111514gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

TNIK BNC2 FMO1 SFRP1 TRIO ADAMTS2 DOCK11 CAPN6 CHD9 JMJD1C RLF ZNF462 ZBTB44 NAV1

1.07e-0479911514gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

BNC2 SFRP1 TRIO ADAMTS2 DOCK11 CHD9 NBEA SFI1 JMJD1C RLF ZNF462 ACE2 ZBTB44 NAV1

1.10e-0480111514gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasMESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05

DOCK3 ABCA2 SFRP1 ADAMTS2 ZNF423 CAPN6 NBEA ZSCAN25 ARHGEF25 BRWD3 RLF DUSP26 ZBTB44 LTN1 XRN1 GOLGA8B ZNF740 KIT

1.25e-04124511518PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO NBEA LINGO2 ADAM22 FRY GOLGA8B PRKCE

7.08e-081961228676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO NBEA ZMAT4 ADAM22 FRY GOLGA8B PRKCE

7.66e-081981228c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO NBEA ZMAT4 ADAM22 FRY GOLGA8B PRKCE

7.66e-0819812286d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO NBEA ZMAT4 ADAM22 FRY GOLGA8B PRKCE

7.66e-0819812288ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DOCK11 SYNE1 ZNF423 WT1 FRY ATF3

6.89e-0718112275f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DOCK11 SYNE1 ZNF423 WT1 FRY ATF3

6.89e-071811227c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 ADAMTS2 WT1 CDC7 JAK2 UGCG NUP188

9.53e-0719012270fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 TRIO DOCK11 ZNF462 UGCG ATP11A

9.88e-0719112271cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO ADAMTS2 CHST11 TEAD4 UGCG ATP11A MAP4K4

1.02e-0619212278b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK BNC2 ABCA2 SYNE1 SFI1 ADAM22 GOLGA8B

1.21e-061971227e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK BNC2 DOCK11 UNC13D CHST11 LINGO2 KIT

1.26e-061981227cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO NBEA ADAM22 FRY GOLGA8B PRKCE

1.26e-0619812274ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK BNC2 DOCK11 UNC13D CHST11 LINGO2 KIT

1.26e-061981227d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SYNE1 PCLO NBEA LINGO2 ADAM22 FRY PRKCE

1.34e-06200122748d801219bc771d6c7e151dc88ca4c179988de85
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 ZSCAN25 TUBGCP5 ZNF462 KICS2 TTC22

6.54e-06166122689e2b8453180983533faccb4275867861876d7ee
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 ZNF234 GIT1 NBEA ATF3 CFAP70

1.04e-05180122612f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 ZNF234 GIT1 NBEA ATF3 CFAP70

1.04e-0518012261bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 ZNF234 GIT1 NBEA ATF3 CFAP70

1.04e-0518012262a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK GIMAP5 CHD9 LYST XRN1 KIT

1.11e-051821226e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK GIMAP5 CHD9 LYST XRN1 KIT

1.11e-0518212261710eab3037a87609d21838be2d2d29c3bc36651
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 BNC2 TBX4 SYNE1 ARHGEF25 ADAM22

1.21e-051851226e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 FMO1 DOCK11 ZNF462 ATP11A

1.29e-0518712269d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 BNC2 TBX4 SYNE1 ARHGEF25 ADAM22

1.33e-0518812263177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DOCK11 SYNE1 WT1 FRY UGCG

1.33e-051881226b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DOCK11 SYNE1 WT1 FRY UGCG

1.33e-051881226874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 TRIO DOCK11 UGCG ATP11A

1.37e-0518912263b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 SFRP1 DOCK11 WT1 ZMAT4 LINGO2

1.45e-051911226156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 LARGE2 PCLO ZMAT4 FRY LRRIQ1

1.50e-051921226b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 TRIO JMJD1C STK3 PRKCE PDZD2

1.50e-051921226e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BNC2 FMO1 SFRP1 ADAMTS2 WT1 ZMAT4

1.54e-051931226cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK GIMAP5 SYNE1 SFI1 TUBGCP5 GOLGA8B

1.54e-0519312269337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 FMO1 SFRP1 ADAMTS2 DOCK11 WT1

1.54e-051931226adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQCH SYNE1 LRRC4 LRRIQ1 ZFHX2 CFAP70

1.73e-05197122674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LARGE2 PCLO CAPN6 ZMAT4 LRRIQ1 ATF3

1.73e-0519712264ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 ZBTB6 FMO1 MINK1 USP46 ZNF550

1.89e-0520012265ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

MAN2A1 IQCH TUBGCP5 STK3 DHFR2 NUP188

1.89e-0520012264db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

MAN2A1 IQCH TUBGCP5 STK3 DHFR2 NUP188

1.89e-052001226d46a19274c2836ce7494790ce513764dedcadc79
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

MBOAT1 CYP2F1 RWDD3 ACE2 TRIM60

5.65e-05149122582edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

MBOAT1 CYP2F1 RWDD3 ACE2 TRIM60

5.65e-05149122514a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 SYNE1 ZNF423 WT1 UGCG

7.46e-051581225e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 SYNE1 ZNF423 WT1 UGCG

7.46e-051581225d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UNC13D ZSCAN25 ZNF276 ZNF740 KIT

7.46e-05158122591d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FMO1 SFRP1 TNFSF13B KIT CALN1

8.64e-051631225bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

BNC2 LRRC4B ADAM22 ZNF462 KIT

9.96e-05168122545ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TNIK BNC2 NBEA NAV1 KIT

9.96e-051681225c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

TNIK BNC2 NBEA LINGO2 KIT

1.02e-041691225fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF346 USP13 TNFSF13B ATF3 ITPRIPL1

1.05e-0417012258465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIO SNX8 NAV1 USP12 MAP4K4

1.05e-041701225cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

TNIK BNC2 NBEA LINGO2 KIT

1.05e-041701225c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNIK FRY PRDM13 TTC22 KIT

1.14e-0417312251e4afa020fae682521335b440ccd33c16f37156f
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR3 NBEA STK3 EDEM3 SNX8

1.14e-041731225b335ca2a247156eba821943b2b9fc9922230b409
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZNF492 SFRP1 LRRC4B NBEA PCNT

1.14e-041731225b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 SYNE1 ATF3 KIT PDZD2

1.21e-041751225cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK11 SPG11 LYST TNFSF13B SOS2

1.24e-04176122576fdf211bce101e83a27d822cb399487bd107027
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MBOAT1 ADAMTS2 SYNE1 ARHGEF25 ATF3

1.27e-04177122584930899eb2978598bc8a351cbcd9e714e46799d
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CYP2F1 LRRC4 LRRIQ1 CFAP70 CCDC181

1.34e-0417912250e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DOCK3 TBX4 CHST11 FRY UGCG

1.34e-04179122514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CYP2F1 LRRC4 LRRIQ1 CFAP70 CCDC181

1.38e-041801225d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZMAT4 LYST JMJD1C TNFSF13B CD300LB

1.41e-04181122571e55acd1d8e4307e56534c74a50e7be4d1dda0d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 FMO1 ACE2 PDZD2

1.41e-0418112259542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 FMO1 ACE2 PDZD2

1.41e-0418112258f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO CHD9 JMJD1C XRN1 ATF3

1.49e-0418312258f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

TNIK FMO1 DOCK11 ZNF462 ACE2

1.53e-04184122551ed1ebfdef45149541917c66cbacad87072e51f
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD9 LYST JMJD1C XRN1 ATF3

1.53e-0418412251154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

USP13 JMJD1C UGCG ATP11A KIT

1.56e-041851225673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD9 LYST JMJD1C XRN1 ATF3

1.56e-0418512257adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 BNC2 TBX4 ARHGEF25 ADAM22

1.60e-0418612256add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

TNIK BNC2 MAN2A1 ZNF462 KIT

1.60e-041861225def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAMTS2 PCLO JMJD1C NAV1 CALN1

1.60e-04186122523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TNIK BNC2 SFRP1 DOCK11 LINGO2

1.60e-0418612258915436d09775f2828a7678af203b1082b36e21c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ABCA2 SFI1 CDC7 LTN1 PCNT

1.60e-041861225927723ad579bbd9947ff525bd501e222d3fa9289
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

TRIO ARHGEF18 SNX8 PRKCE MAP4K4

1.64e-041871225af1327559f7e01bec070881cae52834917c3da65
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 ADAMTS2 CPT1A ATP11A ATF3

1.69e-0418812257da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK TRIO DOCK11 SYNE1 ZNF462

1.69e-04188122563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHD9 LYST JMJD1C TMEM62 PRKCE

1.73e-041891225b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 BNC2 TBX4 SYNE1 ADAM22

1.73e-0418912257ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 PCLO ZMAT4 FRY LRRIQ1

1.73e-0418912257659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARGE2 BNC2 SFRP1 RWDD3 ATF3

1.73e-0418912256f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK BNC2 FMO1 UGCG ATP11A

1.73e-04189122528b502611829e4a24caff2562545c7db97686099
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARGE2 BNC2 SFRP1 RWDD3 ATF3

1.73e-0418912253b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARGE2 BNC2 SFRP1 RWDD3 ATF3

1.73e-04189122538acb307907fde68b992057714448c1561d69ee3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

UNC13D EFR3B GOLGA8B ALDH3A2 PDZD2

1.73e-0418912255a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellMatrixFB-Fibroblast-C|MatrixFB / shred on cell class and cell subclass (v4)

BNC2 SFRP1 ADAMTS2 ZNF423 WT1

1.77e-041901225d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 LARGE2 PCLO FRY LRRIQ1

1.77e-041901225c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TLCD3B USP13 LRRIQ1 BRCA1 PCNT

1.77e-041901225250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellfacs-GAT-Fat-24m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 MAN2A1 ADAMTS2 WT1 NAV1

1.77e-0419012253720e64129f3f3268b1dc14031a76f41c38241c2
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 MAN2A1 ADAMTS2 WT1 NAV1

1.77e-04190122573a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 MAN2A1 ADAMTS2 WT1 NAV1

1.77e-041901225b55cf1fb586b724295b7b038483249847bb344fc
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

BNC2 FMO1 DOCK11 CAPN6 WT1

1.77e-041901225b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BNC2 FMO1 SFRP1 ADAMTS2 WT1

1.77e-0419012254f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 TBX4 SYNE1 ARHGEF25 ADAM22

1.81e-04191122508042952431ca1a6fd7dfc13f36eb28643979598
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TNIK NBEA ZNF462 ZNF550 KIT

1.81e-041911225afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SFRP1 TRIO DOCK11 WT1 ZMAT4

1.86e-041921225d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellNS-critical-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADAMTS2 FPR3 TNFSF13B XRN1 ATF3

1.90e-0419312250dd83b21e164147abfd511a927615c40a28781a2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GIMAP5 FPR3 JMJD1C CD300LB ATF3

1.90e-0419312259fd2bc726bddf414f3de1c7a5ffd9317d3c98e29
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK USP13 SYNE1 ATP11A PDZD2

1.95e-04194122597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 LARGE2 PCLO FRY LRRIQ1

1.95e-041941225f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADAMTS2 FPR3 TNFSF13B XRN1 ATF3

1.95e-041941225e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMAT4 CDC7 JAK2 TNFSF13B UGCG

1.95e-041941225c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEA LRRC4 LRRIQ1 CFAP70 CCDC181

2.00e-0419512259651ee03738226ee10e901f8b9ec6a417eb9c301
DiseaseIntellectual Disability

TRIO SYNE1 NBEA BRWD3 ZNF462 ACE2 FRY BRCA1 ZNF335 ALDH3A2

1.21e-0544711710C3714756
Diseasevital capacity

BNC2 TBX4 IQCH SYNE1 PCLO WT1 UNC13D LINGO2 INO80 JMJD1C LRRIQ1 CLK3 EFR3B BOP1 PDZD2 SOS2

3.06e-05123611716EFO_0004312
Diseaseportal hypertension (is_implicated_in)

GIMAP5 JAK2

1.55e-0451172DOID:10762 (is_implicated_in)
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

MINK1 SPG11 CPT1A JMJD1C CALN1

1.56e-041271175EFO_0008595, EFO_0020947
Diseasesecreted frizzled-related protein 1 measurement

SFRP1 ZMAT4

2.31e-0461172EFO_0020718
DiseaseLeukemia, Myelocytic, Acute

TRIO WT1 JAK2 BRCA1 KIT

6.45e-041731175C0023467
Diseasethrombosis (implicated_via_orthology)

JAK2 ACE2

6.87e-04101172DOID:0060903 (implicated_via_orthology)
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

CPT1A NWD2

8.38e-04111172OBA_2045197
Diseasesialate O-acetylesterase measurement

LINGO2 GOLGA8B

1.00e-03121172EFO_0803073
Diseasepolyunsaturated fatty acids to total fatty acids percentage

CPT1A JMJD1C ZNF335

1.04e-03501173EFO_0022303
DiseasePeripheral Nervous System Diseases

LYST PRKCE ATF3

1.30e-03541173C4721453
Diseasebehavior

MBOAT1 ZNF423 ZMAT4

1.37e-03551173GO_0007610
DiseaseAcute Myeloid Leukemia, M1

TRIO WT1 JAK2 KIT

1.57e-031251174C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

TRIO WT1 JAK2 KIT

1.57e-031251174C1879321
Diseasecortical thickness

TNIK BNC2 SFRP1 ADAMTS2 ZNF423 JMJD1C ZNF462 VPS13D LRRIQ1 NAV1 PDZD2 SOS2

1.58e-03111311712EFO_0004840
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

TNIK TTLL5 JMJD1C C8B

1.87e-031311174C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

TNIK TTLL5 JMJD1C C8B

1.87e-031311174C4552091
DiseaseJuvenile arthritis

TNIK TTLL5 JMJD1C C8B

1.87e-031311174C3495559
DiseaseJuvenile psoriatic arthritis

TNIK TTLL5 JMJD1C C8B

1.87e-031311174C3714758
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

SPG11 CPT1A JMJD1C ZNF335 CALN1

1.95e-032221175EFO_0008317, EFO_0020943
DiseaseGlobal developmental delay

NBEA ZNF462 ZNF335 GABRA5

1.97e-031331174C0557874
DiseaseAcute myeloid leukemia

JAK2 KIT

2.04e-03171172cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

JAK2 KIT

2.04e-03171172601626
Diseasecreatinine measurement

TBX4 MBOAT1 ARHGEF18 CHD9 INO80 BRWD3 EDEM3 FRY CFAP70 ALDH3A2 SOS2

2.04e-0399511711EFO_0004518
Diseaseapolipoprotein A 1 measurement

UNC13D SPG11 LINGO2 CPT1A ARHGEF25 JMJD1C TMEM62 TNFSF13B SNX8 KIT

2.05e-0384811710EFO_0004614
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

SPG11 CPT1A JMJD1C ZNF335 CALN1

2.07e-032251175EFO_0008317, EFO_0020947
Diseasesevere acute respiratory syndrome, COVID-19

ARHGEF18 ZMAT4 LYST USP12 GOLGA8B ATP11A PDZD2

2.08e-034471177EFO_0000694, MONDO_0100096
DiseaseJuvenile-Onset Still Disease

TNIK TTLL5 JMJD1C C8B

2.08e-031351174C0087031
Diseaseskin pigmentation measurement

BNC2 GIMAP5 ZNF276 ATP11A

2.20e-031371174EFO_0007009
DiseaseMalignant neoplasm of liver

TRIO LINGO2 PRKCE ATF3

2.50e-031421174C0345904
Diseasestomach cancer (is_marker_for)

NBEA JAK2 BRCA1 MAP4K4

2.50e-031421174DOID:10534 (is_marker_for)
DiseaseLiver neoplasms

TRIO LINGO2 PRKCE ATF3

2.50e-031421174C0023903
DiseaseChronic myeloproliferative disorder

KIT PCNT

2.55e-03191172C1292778
DiseaseNon-alcoholic Fatty Liver Disease

CPT1A JAK2 PRKCE

2.74e-03701173C0400966
DiseaseNonalcoholic Steatohepatitis

CPT1A JAK2 PRKCE

2.74e-03701173C3241937
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

DOCK3 GIT1

2.83e-03201172DOID:1094 (is_implicated_in)
DiseaseBipolar Disorder

SFRP1 SYNE1 PCLO USP46 PIP4K2C PCNT GABRA5

2.98e-034771177C0005586
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

SPG11 CPT1A JMJD1C CALN1

3.05e-031501174EFO_0004611, EFO_0020947
Diseasedocosahexaenoic acid to total fatty acids percentage

CPT1A JMJD1C

3.12e-03211172EFO_0022262
Diseaseneutrophil count

BNC2 FMO1 ZNF423 CHD9 JMJD1C JAK2 BRCA1 TNFSF13B UGCG MRPS15 KIT MAP4K4 PCNT

3.33e-03138211713EFO_0004833
DiseaseIGF-1 measurement

DOCK3 MC3R CHST11 LINGO2 ZNF462 JAK2 PIP4K2C

3.38e-034881177EFO_0004627
Diseasepulse pressure measurement

BNC2 IQCH ZNF423 WT1 UNC13D NBEA CHST11 INO80 ARHGEF25 NAV1 UBR3 PRKCE SOS2

3.54e-03139211713EFO_0005763

Protein segments in the cluster

PeptideGeneStartEntry
RSHLHQRKYLKIMPV

TMEM62

561

Q0P6H9
YRMLRHHKKALRAVA

BOP1

656

Q14137
HHVRTLKIMLKVYSR

ARHGEF18

461

Q6ZSZ5
AQLFIKHERRLHMYV

ARHGEF25

236

Q86VW2
HTNKMIFRLLKHAIC

CXorf58

56

Q96LI9
YSVKLHYRNVHLKEM

BNC2

846

Q6ZN30
MFKKHRLSVVHTNTY

ADAM22

251

Q9P0K1
IPSHMIHRTRKQKYF

CLK3

541

P49761
KLFKLASEKHQHMYR

CPT1A

631

P50416
IFPSSAYQHIKMHKR

BRWD3

161

Q6RI45
AYQHIKMHKRILGHL

BRWD3

166

Q6RI45
LYVFSHNHKLIKRMI

ALDH3A2

361

P51648
FIRAKYQMLAFVHKL

GIT1

106

Q9Y2X7
ILYHAFRDHLTMKDI

CALN1

181

Q9BXU9
FHGKEHVQKYLLTLM

ADAMTS2

281

O95450
IFFVNHRKMSELLYH

NWD2

826

Q9ULI1
TLHHAFLALMKYPKV

CYP2F1

306

P24903
ILYEHLKRHKLGMLT

IQCH

941

Q86VS3
MSKLSHKHLVLNYGV

JAK2

601

O60674
VKSMLFYRKNPLHLH

LARGE2

116

Q8N3Y3
ELHNMLRLHKYKKLH

INO80

156

Q9ULG1
TKSLNKLLYHLFRLM

LTN1

1506

O94822
IKLEINMLKKYSHHR

MAP4K4

66

O95819
LSHMLIQRVHYAVKK

MAN2A1

306

Q16706
MIKSVKRAYHRLCLH

KIT

171

P10721
MFLHQHGVIYRDLKL

PRKCE

521

Q02156
LYHAVKEMVRALKIH

JMJD1C

2516

Q15652
THEMLYQVIKKHNFL

EDEM3

371

Q9BZQ6
YGIIAAKIHRNHMIK

FPR3

221

P25089
KTMHYIFPHARIKIT

PCLO

4486

Q9Y6V0
HYRTIMSHKLLKGFA

OR4L1

131

Q8NH43
IYLIMLRRFKHKAHS

PDZD2

171

O15018
VFMKKHSQQLYRHIY

EFR3B

516

Q9Y2G0
AAMLIVFYKLRKRHQ

LRRC4

541

Q9HBW1
MPVYAFKRLFHLKHL

LINGO2

216

Q7L985
IMTAHFHLKRKIGYF

GABRA5

246

P31644
LRVKLMHFVNSLHNY

TUBGCP5

886

Q96RT8
HTSNVKMEKLYLHYL

PCNT

3126

O95613
FKKLMILSTEYRHAH

LRRIQ1

1201

Q96JM4
KHLMLLHYEIFVFLL

GIMAP5

276

Q96F15
AIMKKYSSRFHHPIL

KICS2

166

Q96MD2
SYHFKTALMHLLLRL

ITPRIPL1

446

Q6GPH6
EFMLVYKFARKHHIT

BRCA1

1661

P38398
RSKQLQHHLYMSEAK

CCDC181

486

Q5TID7
KHHCNKVLLRVRMLY

CHD9

1621

Q3L8U1
RRHAFELKMLDKYSH

DOCK11

236

Q5JSL3
KHKVDLFYKLRHVMN

DOCK3

106

Q8IZD9
EYMLNLFKALKRIHQ

CDC7

156

O00311
HFLMKVKAVQYVHRV

CFAP70

901

Q5T0N1
LKMYANHFDLLKHIQ

FMO1

91

Q01740
AMLKERHHTKVQYQL

ABCA2

2306

Q9BZC7
LYEHLHAYVRAKLMN

ACE2

236

Q9BYF1
KNEKQHLIYMLNLHR

ATF3

136

P18847
HFMAIIYTRLHLNKK

UGCG

26

Q16739
HKLIFMIIQKLFRSH

LYST

991

Q99698
YIAFIEGKHIHMKLL

MBOAT1

206

Q6ZNC8
LYVHMFLFARLHVKR

MC3R

206

P41968
VYKEAMNHLGHLKLF

DHFR2

121

Q86XF0
KLSNLAHVMTLYKTH

FRY

2181

Q5TBA9
KLNTDLYHMKHSLRY

GOLGA8B

136

A8MQT2
FKVEMNRKFRLHHLY

CAPN6

426

Q9Y6Q1
YCRMHVTQLHTAKKL

ERVFC1

111

P60507
LYSRKYGLKIHMRTH

PRDM13

581

Q9H4Q3
VAHYKLKPRSLMLHY

C8B

301

P07358
VMLVAFYKLRKQHQL

LRRC4B

591

Q9NT99
SLRNKDMKYALHHVF

OR11H7

291

Q8NGC8
MFSHRLPVHRKYDLK

PIP4K2C

206

Q8TBX8
IKQEINMLKKYSHHR

MINK1

66

Q8N4C8
MQHYISLLLKHRRLV

NAV1

1541

Q8NEY1
HRKDKAHKRYLLMSI

MRPS15

146

P82914
LYAHHAQVEKLARKM

SFI1

336

A8K8P3
YSHQLRSKHLAIKKM

SOS2

406

Q07890
KHQRALHKYSLMKRQ

SNX8

341

Q9Y5X2
KMLHLVTLYHRLKRQ

SYNE1

4751

Q8NF91
HNNHMAKVLTLELYK

CKM

26

P06732
YFLKHLGHKRKVEIM

NBEA

771

Q8NFP9
MKNLRKLVFSRCHHY

PRAMEF1

231

O95521
HHFLIMGRKVKSQYL

SFRP1

266

Q8N474
YLMLYHHLTLVEAIK

DUSP26

166

Q9BV47
HKRNHYMLLVFVKVP

CD300LB

146

A8K4G0
EINHRLKSYMKFLFV

CHST11

171

Q9NPF2
KMLLVHGHFYYIRIS

ATP11A

866

P98196
QKHYFMLRHPKLIKL

NLRP9

281

Q7RTR0
HKFPRKSQLLEHMYT

ZBTB25

356

P24278
FDLLHKKHYFEVLMR

SPG11

2176

Q96JI7
ITLLHLDHMRAKTKY

RWDD3

141

Q9Y3V2
LKGLEYLHFMRKIHR

STK3

131

Q13188
YLHFMRKIHRDIKAG

STK3

136

Q13188
IKQEINMLKKYSHHR

TNIK

66

Q9UKE5
GKKFYLSNHLRRHMI

ZNF653

506

Q96CK0
YKQISTLAMHKRTAH

ZNF143

426

P52747
LLVHYNSVSHLHKMK

ZFHX2

1206

Q9C0A1
REALLMHYLKKHNYS

RLF

1141

Q13129
LREYLMKHQRTHLGK

ZSCAN25

386

Q6NSZ9
FTRAYSLKMHRLKHE

ZBTB44

436

Q8NCP5
ALHLKRFKYMDQLHR

USP12

256

O75317
FMIDRYLQRHVKLIH

ZNF276

476

Q8N554
ALMKKYTRHHSLKFA

TLE7

366

A0A1W2PR48
ARLHEHLKYFVNMKI

XRN1

141

Q8IZH2
NKRYFKLSHLQMHSR

WT1

331

P19544
LLHSRKMLQHYLQNK

NUP188

1491

Q5SRE5
LCEYMINFIHKLKHL

TEAD4

366

Q15561
LELLTQAKSMHHKYQ

TRIM60

246

Q495X7
GKSFRMKIHYQVHLV

ZNF234

406

Q14588
ILNRHKMIHTGEKLY

ZNF492

491

Q9P255
KAFKRRSYLMQHHPI

ZNF550

266

Q7Z398
LALHLKRFKYMEQLH

USP46

251

P62068
KHANKVKRYLAIHGM

ZNF346

96

Q9UL40
HIVLFTLLYKILMDH

UBR3

926

Q6ZT12
IARGYLHKEFLMVLH

TLCD3B

121

Q71RH2
YHTKYKRNMIDHIVL

ZNF462

2261

Q96JM2
LNSMHKYQPRLHIVK

TBX4

186

P57082
DLQKHLLDMHTFVLY

ZNF423

706

Q2M1K9
YAMGHLIQRKKVHVF

TNFSF13B

206

Q9Y275
MRFIQKYHLERHKRV

ZNF740

136

Q8NDX6
KRYTFKMHLLTHIQA

ZNF335

601

Q9H4Z2
IHIRAYLHDLKRAKM

TTC22

341

Q5TAA0
ALMFLSLYLIHKRTH

ZNF433

206

Q8N7K0
KIFHNTLKIHLFSMA

UNC13D

511

Q70J99
RKHASKVRLYYMLHP

ZMAT4

36

Q9H898
QSVYMHLKRHVREKV

USP13

86

Q92995
KDRLYKNIIRMQHTH

TTLL5

131

Q6EMB2
SLFVKHERRLHMYIA

TRIO

2046

O75962
KLIYFQLHRALKMIV

TRIM28

366

Q13263
LHVENYLRHLKMHKL

ZBTB6

311

Q15916
YLRHLKMHKLFLCLQ

ZBTB6

316

Q15916
LKMASLHYNHSAKFL

VPS13D

1286

Q5THJ4