Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainHEAT_type_2

PIK3R4 MROH1 GCN1

3.03e-0517683IPR021133
DomainHEAT

PIK3R4 MROH1 GCN1

7.10e-0448683PF02985
DomainHEAT

PIK3R4 MROH1 GCN1

1.23e-0358683IPR000357
DomainHEAT_REPEAT

PIK3R4 MROH1 GCN1

2.12e-0370683PS50077
DomainZnf_C2H2

ZNF438 ZBTB38 ZSCAN20 ZNF805 ADAMTS17 ZNF778 ZFR ZNF831 ZNF865

2.48e-03805689IPR007087
PathwayREACTOME_PLATELET_HOMEOSTASIS

PDE1B GNG11 LRP8 ITPR2

5.56e-0576394MM15051
PathwayREACTOME_PLATELET_HOMEOSTASIS

PDE1B GNG11 LRP8 ITPR2

9.02e-0586394M916
Pubmed

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.

ZNF438 ZBTB38 ADAMTS17 KCNQ1 NHEJ1

8.38e-0613670525429064
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

UNC5C LNPK PEAK1 GPRIN1

4.00e-059470432062451
Pubmed

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.

ZBTB38 ADAMTS17 NHEJ1

5.78e-053770319266077
Pubmed

Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.

ZSCAN20 CSMD2

2.17e-041170216429158
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

RPAP1 ZFR TTC17 GCN1 ITPR2

2.79e-0428570532838362
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2D CEBPB MROH1 RPAP1 AHNAK ZNF865 GCN1 BAHCC1 ITPR2

3.65e-04110570935748872
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

KMT2D AHNAK BRD7 ZNF831 GCN1 MECP2

3.68e-0446970627634302
Pubmed

Rb regulates fate choice and lineage commitment in vivo.

CEBPB PPP1R9A

4.71e-041670220686481
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

KMT2D CEBPB

4.71e-041670224368734
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PIK3R4 SLC7A2 LNPK GPRIN1 LRP8 ITPR2

5.38e-0450470634432599
Pubmed

The DNA sequence and comparative analysis of human chromosome 20.

WFDC3 CEBPB LZTS3 ENTPD6 RPS10P5 ZNF831

6.15e-0451770611780052
Pubmed

Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.

NSUN3 KCNQ1

6.68e-041970224165912
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RPAP1 AHNAK PPFIA3 CSMD2 GPRIN1 ZNF831 ITPR2

6.98e-0473670729676528
Pubmed

A novel common variant in DCST2 is associated with length in early life and height in adulthood.

ZBTB38 TTC17

7.41e-042070225281659
Pubmed

Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits.

GRM8 MECP2

7.41e-042070235365601
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2D AHNAK ZFR PEAK1 GPRIN1 GCN1

8.40e-0454970638280479
Pubmed

Genome-wide association analysis identifies 20 loci that influence adult height.

ZBTB38 NHEJ1

8.99e-042270218391952
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

AHNAK UNC5C ZFR PEAK1 GPRIN1 ZNF865 GCN1

9.57e-0477770735844135
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KMT2D AHNAK PPP1R9A PEAK1 PPFIA3 GPRIN1 GCN1 ITPR2

1.20e-03104970827880917
Pubmed

The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.

SKOR1 LRP8

1.46e-032870224491816
Pubmed

Identification of Arx transcriptional targets in the developing basal forebrain.

UNCX SKOR1

1.46e-032870218799476
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

RPAP1 PDE1B RPS10P5 LNPK

1.55e-0324670415345747
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PPP1R9A UNC5C PEAK1 GPRIN1 LRP8

1.61e-0342170536976175
Pubmed

The synaptic vesicle cycle.

CPLX2 PPFIA3

1.79e-033170215217342
Pubmed

HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.

CEBPB MECP2

1.90e-033270211748221
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C CPLX2 ADAMTS17 PEAK1 GNG11

3.87e-07179706948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB UNC5C ADAMTS17 PEAK1 GNG11 MCTP2

5.66e-071917063379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFBP4 AHNAK PEAK1 ZNF831 GRM8

5.70e-0616270558da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellHealthy_Control-Lymphoid-NK-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PPP1R9A UNC5C GZMM SKOR1 MCTP2

9.00e-0617870571e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCell(1)_Control_(PBS)|World / Stress and Cell class

CEBPB IGFBP4 AHNAK PEAK1 GNG11

1.27e-05191705b346e13259cb2d506b923ad44b894c21a3eee4c3
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB UNC5C ADAMTS17 PEAK1 GNG11

1.36e-05194705f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C ADAMTS17 PEAK1 GNG11

1.40e-05195705598b69032a8441a23749b27863d80f7a1fc82a96
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB UNC5C ADAMTS17 PEAK1 GNG11

1.40e-05195705b072fdc2131173f562e55dd78226eaf2c57d3690
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C ADAMTS17 PEAK1 GNG11

1.43e-051967052a885eed52f9b002c7995e11e450c7e8d7ae69e6
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C ADAMTS17 PEAK1 GNG11

1.43e-0519670514246f00c90741a5f8683f377e22e3a7c99661b9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFBP4 AHNAK PEAK1 GRM8

9.41e-05151704f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC3 CEBPB UNCX GPRIN1

9.41e-05151704ced4f7ee377a23a804ae6fde624e8b55b79f1fd8
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC3 CEBPB UNCX GPRIN1

9.41e-05151704b52bb3b88e9a6473f571053537b8beb418678539
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPAP1 ADAMTS17 PANX2 LRP8

9.90e-051537048bc09b8b1a32a8d7ac8201c626d2b306e7cc2972
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ESYT3 ZSCAN20 CASP2 PNO1

1.04e-04155704d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCellBac-SEP-Lymphocyte-T_NK-NK_CD56bright|Bac-SEP / Disease, Lineage and Cell Type

IGFBP4 RPAP1 PPP1R9A GZMM

1.12e-0415870420411158d71699a80f6c1566791af89dea0e1875
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

IGFBP4 PPP1R9A GZMM ZNF831

1.15e-041597049e2067f0d76769717f7048dab505fadd36bbb83e
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCC PROB1 LNPK MECP2

1.15e-0415970408a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCC PROB1 LNPK MECP2

1.15e-041597049bdfa7f5aa7753fe25b787bd43d694b6093d77eb
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFBP4 AHNAK PEAK1 ZNF831

1.23e-041627044d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

1.29e-04164704b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellHealthy-NK_CD56bright|Healthy / disease group, cell group and cell class

IGFBP4 PPP1R9A GZMM MCTP2

1.29e-04164704ed193211965accba60a256d3e6c159f0fc911d8b
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

IGFBP4 PPP1R9A ADAMTS17 MCTP2

1.36e-04166704ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TRANK1 AHNAK LNPK GCN1

1.39e-04167704948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellHealthy-NK_CD56bright|World / disease group, cell group and cell class

IGFBP4 PPP1R9A GZMM MCTP2

1.39e-04167704ab7a570a75ee2018b9fe886cdec79cda27f1563f
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CSMD2 RINL GNG11 ITPR2

1.42e-04168704327b02f19f4a8607c033203824fdc60a1254331f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ESYT3 ZBTB38 GZMM GNG11

1.42e-04168704b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGFBP4 UNC5C ADAMTS17 GNG11

1.49e-041707047fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.52e-041717046a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZSCAN20 GZMM ADAMTS17 MCTP2

1.52e-04171704f16cb64b8844c2668922c786888efaa9f873afcc
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC7A2 CEBPB ENTPD6 LRP8

1.52e-04171704845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.52e-04171704e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|367C / Donor, Lineage, Cell class and subclass (all cells)

GZMM BRD7 RINL MCTP2

1.55e-041727046379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

PPP1R9A ADAMTS17 PEAK1 MCTP2

1.59e-041737044a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GZMM ZNF831 HECA LRP8

1.59e-041737047186add017271382ecafbff8ee87afb45fbfc745
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESYT3 GZMM CASP2 BAHCC1

1.66e-04175704aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRANK1 LZTS3 GZMM NUDT8

1.66e-04175704a3f8c54c77bce9b035a4835945ab341909be4946
ToppCellprimary_visual_cortex-Non-neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC7A2 PPP1R3G GNG11 ITPR2

1.70e-041767042c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF438 CEBPB SKOR1 GCN1

1.73e-041777041d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SLC7A2 IGFBP4 PDE1B UNC5C

1.81e-04179704342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellfrontal_cortex-Non-neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC7A2 PPP1R3G GNG11 ITPR2

1.81e-04179704ef01478bd03eb00f0ff2b6a8ae9244687c5f85aa
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.85e-04180704bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.85e-04180704839defb40f7cfb2711e9025194de636533f51bcd
ToppCellmild_COVID-19-NK_CD56bright|mild_COVID-19 / disease group, cell group and cell class (v2)

IGFBP4 PPP1R9A CSMD2 MCTP2

1.85e-04180704d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.85e-04180704df60970520fba2ac0639faa54096766d07418ca4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNCX CPLX2 SKOR1 GPRIN1

1.85e-041807046ac62bf1251978c8c12e715f7b73144fca619794
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPAP1 UNCX LZTS3 MCC

1.85e-04180704c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.85e-0418070482965ed1b72a1873c24dd4553d39681596057316
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

1.89e-041817044795833e0ec49287bd7809ecfe523fc527565fba
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

1.89e-04181704208cdccc2f0d0f2d8ec321064c63aed206d46c32
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCC PEAK1 GNG11 ITPR2

1.89e-0418170492d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

1.89e-041817049c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.89e-04181704782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.89e-04181704e2481291c236105774c53883e6f20da11941df9b
ToppCellfacs-Marrow-B-cells-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GRM8 MCTP2 LRP8

1.89e-04181704e6c78038b14100e0c9c6fe25e8f0b75c02c33549
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB UNC5C ADAMTS17 PEAK1

1.93e-04182704ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

IGFBP4 MCC GRM8 GNG11

1.93e-04182704a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESYT3 KMT2D CPLX2 MCTP2

1.93e-041827041923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESYT3 KMT2D CPLX2 MCTP2

1.93e-0418270469ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellHealthy_Control-Lymphoid-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

UNC5C GZMM SKOR1 MCTP2

1.97e-04183704b41b1f32022c8632a638cf1c5523c9a24176f568
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PPP1R9A CSMD2 ZNF831 GRM8

2.01e-041847046e17c8151d6dc543de16d804db956c63c3fda414
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

2.05e-041857043b2da51aec057b462749ae39afb8f253afcf38d5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 MCC GRM8 LRP8

2.10e-04186704948815663c212c4311329d503b5991cbbbff9808
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PPP1R9A GZMM ZNF831 MCTP2

2.10e-04186704165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

2.10e-041867045ad37549592eab23f166196ebf0cb9c8ddf26082
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRANK1 PDE1B PANX2 GPRIN1

2.10e-041867043f889083fcffe516388e9b03a5e23af2010ced33
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 UNCX GPRIN1 GRM8

2.10e-04186704d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNCX CPLX2 SKOR1 PANX2

2.14e-04187704ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGFBP4 AHNAK GZMM ZNF831

2.14e-04187704f1ba41f2ec703251a81c46e08d45e70210f298e7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNCX CPLX2 PANX2 GPRIN1

2.14e-041877041b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLX2 PANX2 PPFIA3 ZNF831

2.14e-04187704e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLX2 PANX2 PPFIA3 ZNF831

2.14e-0418770424cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLX2 PANX2 PPFIA3 ZNF831

2.14e-041877042f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GZMM ADAMTS17 ZNF831 MCTP2

2.18e-041887046686dbba990066568aa7573e70a7db8b4758f457
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

SLC7A2 PPP1R9A MCTP2 SPINK5

2.18e-04188704ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

IGFBP4 UNC5C ADAMTS17 PEAK1

2.18e-041887046740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

IGFBP4 PPP1R9A GZMM MCTP2

2.18e-041887048ee359199c61c3b5b498ac35148390db5cc1a836
ToppCellHealthy_donor-NK_CD56bright|Healthy_donor / disease group, cell group and cell class (v2)

IGFBP4 PPP1R9A GZMM MCTP2

2.23e-041897049eac380a3bb4b685effb52d816e1960972660646
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IGFBP4 UNC5C ADAMTS17 PEAK1

2.23e-04189704dc5164591dea45b420798b94dda211be03daa70c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 MCC GRM8 LRP8

2.23e-0418970478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

IGFBP4 PPP1R9A ADAMTS17 MCTP2

2.23e-041897046e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
ToppCellControl-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

GZMM ADAMTS17 ZNF831 MCTP2

2.23e-04189704ee4c1d930534788a7759d92dc8ff9c62e6ee2301
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IGFBP4 PPP1R9A GZMM MCTP2

2.23e-041897043e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 MCC GRM8 LRP8

2.27e-0419070439ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 MCC GRM8 LRP8

2.27e-041907040acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellCOVID-19-Heart-Mito_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 IGFBP4 PROB1 GNG11

2.27e-04190704ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A2 CPLX2 ZFR GPRIN1

2.32e-04191704b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SLC7A2 IGFBP4 PDE1B UNC5C

2.32e-04191704fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB IGFBP4 UNC5C ADAMTS17

2.32e-04191704a05e9a7eb137d804570dd7d8905975d735738767
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD56bright_CD16-|Lung / Manually curated celltypes from each tissue

IGFBP4 GZMM ADAMTS17 MCTP2

2.32e-0419170412ce360dc149c85d5a22cfc1bf53d54aef79edc1
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZBTB38 AHNAK GZMM ZNF831

2.32e-041917044a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP4 PPP1R9A GNG11 BAHCC1

2.36e-04192704959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C ADAMTS17 PEAK1

2.36e-0419270425492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellT/NK_cells-CD56bright_NK_cell|World / Lineage and Cell class

IGFBP4 PPP1R9A GZMM MCTP2

2.36e-04192704528b5b790a0e8966d04ffbc83b049c93bac17537
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC7A2 IGFBP4 UNC5C ADAMTS17

2.36e-04192704f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellMS-NK-|MS / Condition, Cell_class and T cell subcluster

IGFBP4 PPP1R9A GZMM MCTP2

2.36e-04192704f97f5f8226f5c65ca93072ef35d753231bee2490
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC7A2 IGFBP4 UNC5C ADAMTS17

2.36e-04192704df1545670370fb1010c567cd059c2783eab315f7
ToppCellMS-NK|MS / Condition, Cell_class and T cell subcluster

IGFBP4 PPP1R9A GZMM MCTP2

2.36e-04192704f44f5dd30db169fdd16c9d706d17ad44907a17af
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP4 UNC5C ADAMTS17 PEAK1

2.36e-04192704de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB IGFBP4 UNC5C ADAMTS17

2.36e-041927040afb9dbe468e0be442c326e11c5fc0f699b32f23
Diseasecarpal tunnel syndrome

ZNF438 ZBTB38 ADAMTS17 LNPK

4.83e-0589664EFO_0004143
Diseasedisposition index measurement, glucose homeostasis measurement

ZNF438 KCNQ1

2.19e-0410662EFO_0006832, EFO_0006896
DiseaseDevelopmental Academic Disorder

PDE1B MECP2

1.92e-0329662C1330966
DiseaseLearning Disorders

PDE1B MECP2

1.92e-0329662C0023186
DiseaseLearning Disturbance

PDE1B MECP2

1.92e-0329662C0751263
DiseaseAdult Learning Disorders

PDE1B MECP2

1.92e-0329662C0751262
DiseaseLearning Disabilities

PDE1B MECP2

1.92e-0329662C0751265
Diseasehair colour measurement

KMT2D ZBTB38 AHNAK ZNF778 ZNF831 DDB2

2.52e-03615666EFO_0007822
DiseasePapillary Renal Cell Carcinoma

AHNAK UNC5C CASP2

2.99e-03128663C1306837
DiseaseRenal Cell Carcinoma

AHNAK UNC5C CASP2

2.99e-03128663C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

AHNAK UNC5C CASP2

2.99e-03128663C1266043
DiseaseChromophobe Renal Cell Carcinoma

AHNAK UNC5C CASP2

2.99e-03128663C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

AHNAK UNC5C CASP2

2.99e-03128663C1266044
DiseaseIntellectual Disability

ALKBH8 CASP2 MCC LNPK MECP2

3.27e-03447665C3714756
DiseaseMental Retardation, Psychosocial

CASP2 MCC MECP2

3.77e-03139663C0025363
DiseaseProfound Mental Retardation

CASP2 MCC MECP2

3.77e-03139663C0020796

Protein segments in the cluster

PeptideGeneStartEntry
PKGKDSAKRFCEPIG

ESYT3

666

A0FGR9
CTLDKTVGKEAPAGP

BAHCC1

521

Q9P281
EESPDKDGLLKPTCG

ANKRD30B

761

Q9BXX2
FELIKCEDPGTPKFG

CSMD2

1206

Q7Z408
EEPKKTDVAECGPGG

BRD7

636

Q9NPI1
DKDKPLSGGLPDICE

ALKBH8

191

Q96BT7
DSKDQAPCKGDSGGP

GZMM

196

P51124
VPDVDLECPDAKLKG

AHNAK

1826

Q09666
DQPKCSPEKDGLGSS

SLC7A2

441

P52569
KLDPPLDGTECGADK

ADAMTS17

511

Q8TE56
KGDVSFPGGKCDPAD

NUDT8

61

Q8WV74
LKPGSDPDEGDEALK

ITPR2

2126

Q14571
KPLDPERKLEDAGSC

FAM47C

151

Q5HY64
DGEKVLDLCAAPGGK

NSUN3

131

Q9H649
AKKCPFSLELAEGGP

KCNQ1

31

P51787
LGGDAPEEPEKLCGS

MCTP2

146

Q6DN12
ELGEGELPAACLKPA

LZTS3

506

O60299
TGRPPGEAAEEAKKC

HECA

211

Q9UBI9
CPKDLKPVCGDDGQT

SPINK5

1006

Q9NQ38
DPLGLAKLTGPGDKD

PPFIA3

801

O75145
GDKEAELGLPFSPLC

PDE1B

396

Q01064
KGETDGKNPKPCSEA

PEAK1

1426

Q9H792
SELGKCVAGKDLPEG

GCN1

31

Q92616
PPLCGDGLLSGKEET

PNO1

61

Q9NRX1
EPEAKKLCAKGSGPS

DDB2

31

Q92466
ALLPEPKEEDGGCQK

MROH1

876

Q8NDA8
KDASDVKCANGDPPI

GRM8

126

O00222
AKEPPCARAKEEAGA

H1-7

196

Q75WM6
ELDSNKGPDCNKTPG

CCDC82

66

Q8N4S0
DKPGKECADAASPAL

MCC

691

P23508
AELKAEPGFEPADCK

CEBPB

171

P17676
PADCKRKEEAGAPGG

CEBPB

181

P17676
LAKGEVPKGSCEDEP

ATE1

101

O95260
GIPEDKNPFKEKGSC

GNG11

56

P61952
DPGSCRKAEPLASGK

GPRIN1

671

Q7Z2K8
PGCEESDAGKEKLPK

CASP2

341

P42575
RPKKAIPAGCGDEEE

CPLX2

96

Q6PUV4
PLLGGQGPAKDCEKD

LRP8

36

Q14114
EDCGLGLAPAPIKDA

PANX2

551

Q96RD6
GGSLESDGCPKEPAK

MECP2

421

P51608
TAFGLCPKKDDPVLG

SKOR1

401

P84550
CPKKDDPVLGAGEPK

SKOR1

406

P84550
EGQPAKDGKELVSPC

ENTPD6

311

O75354
KKPGEVDDSLEQPCG

SLCO6A1

76

Q86UG4
EKLPEACSIGDGKPF

NHEJ1

196

Q9H9Q4
PGSGDAKKEPGAECF

PPP1R3G

286

B7ZBB8
KLPGGLEPKGELDCH

IGFBP4

236

P22692
GTLDADKCPEVLGPG

PROB1

596

E7EW31
EFGGDGKLDPLCEKA

C10orf53

71

Q8N6V4
DLPEKAEGEPKENGL

PIK3R4

361

Q99570
KKDEDPGPALETAVC

RINL

336

Q6ZS11
KQKLAEFGGECPADP

WFDC3

116

Q8IUB2
GPPAAAACDPTKDDK

ZNF865

196

P0CJ78
PGEKPCELEECGKAS

ZNF778

276

Q96MU6
AEKELCKDPPGDDCG

ZSCAN20

236

P17040
CSVPPGADKKAEAGA

RPS10P5

141

Q9NQ39
DLGPCEGPSKEDKDL

SPANXN3

101

Q5MJ09
EDEECPAGKAKRKSP

RPAP1

506

Q9BWH6
DPDCIKAKVPLGDLD

TTC17

111

Q96AE7
LKGSPGLLDPCEKDP

ZFR

981

Q96KR1
AELDCAVGKAPQDKP

ZBTB38

956

Q8NAP3
ECGNGPDDQGKILPK

XAGE3

81

Q8WTP9
ESPPCCGKEEKKEGD

ZNF831

1356

Q5JPB2
KDDKPTLGAGAPDCS

TRANK1

726

O15050
TAPAPKNGGKDCDGL

UNC5C

341

O95185
GPKADCDKIPSTTEG

ZNF438

321

Q7Z4V0
TLKGDEEAGAEAPPK

XIRP1

356

Q702N8
EDLSQGTCPGDKGKP

ZNF805

76

Q5CZA5
SDSGDPDKESPGCKR

UNCX

91

A6NJT0
PSDALGPDDKKDGDL

KMT2D

1631

O14686
LEAGKLPCEDPELDD

KMT2D

2981

O14686
PDSKKAKECEPPSAG

LNPK

141

Q9C0E8
IDKDGPEEPCAESKA

PPP1R9A

316

Q9ULJ8