Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

LRRC8C MFHAS1 NLRX1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL FBXL19 LRRC58 STK11IP LRRC8D BGN CNOT6 TSKU LRRC14B SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TBCEL TPBG PHLPP2 NLRP13 GP5

5.63e-20321181293.80.10.10
DomainLRR_8

LRRC8C MFHAS1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL LRRC58 LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TPBG PHLPP2 GP5

6.41e-2017118123PF13855
DomainLeu-rich_rpt

LRRC8C MFHAS1 NLRX1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL FBXL19 LRRC58 STK11IP LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TPBG PHLPP2 NLRP13 GP5

9.41e-2027118127IPR001611
DomainL_dom-like

LRRC8C MFHAS1 NLRX1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL FBXL19 LRRC58 STK11IP LRRC8D BGN CNOT6 TSKU LRRC14B SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TBCEL TPBG PHLPP2 NLRP13 GP5

1.02e-1932818129IPR032675
DomainLRR_TYP

LRRC8C MFHAS1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL LRRC58 LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TPBG PHLPP2 GP5

1.43e-1917718123SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC8C MFHAS1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL LRRC58 LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TPBG PHLPP2 GP5

1.43e-1917718123IPR003591
DomainLRR_1

LRRC8C MFHAS1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL FBXL19 LRRC58 LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB RTN4RL2 TPBG PHLPP2 GP5

1.28e-1821918124PF00560
DomainLRR

LRRC8C MFHAS1 LRRK2 LRTM1 PIDD1 LINGO3 TLR7 CHADL LRRC58 STK11IP LRRC8D BGN CNOT6 TSKU SLITRK2 LRFN2 LGI3 LRRC1 LRRC7 SCRIB TPBG PHLPP2 GP5

2.63e-1820118123PS51450
DomainLRRNT

LRTM1 LINGO3 TLR7 CHADL BGN TSKU SLITRK2 LRFN2 RTN4RL2 TPBG GP5

2.82e-099818111IPR000372
DomainLRRNT

LRTM1 LINGO3 TLR7 CHADL BGN TSKU SLITRK2 LRFN2 RTN4RL2 TPBG GP5

2.82e-099818111SM00013
DomainCys-rich_flank_reg_C

LRTM1 LINGO3 TLR7 CHADL SLITRK2 LRFN2 LGI3 RTN4RL2 TPBG GP5

1.67e-089018110IPR000483
DomainLRRCT

LRTM1 LINGO3 TLR7 CHADL SLITRK2 LRFN2 LGI3 RTN4RL2 TPBG GP5

1.67e-089018110SM00082
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.85e-04121813PF15371
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.85e-04121813IPR027970
DomainLRRCT

TLR7 LGI3 TPBG GP5

2.48e-04321814PF01463
DomainHedgehog_signalling_dom

SHH DHH

2.78e-0431812IPR000320
DomainHintN

SHH DHH

2.78e-0431812SM00306
DomainHintC

SHH DHH

2.78e-0431812SM00305
DomainHedgehog

SHH DHH

2.78e-0431812IPR001657
DomainRyanodine_rcpt

RYR1 RYR2

2.78e-0431812IPR003032
DomainHH_signal

SHH DHH

2.78e-0431812PF01085
DomainHint

SHH DHH

2.78e-0431812PF01079
DomainHedgehog_sig/DD-Pept_Zn-bd_dom

SHH DHH

2.78e-0431812IPR009045
DomainHint_dom

SHH DHH

2.78e-0431812IPR001767
DomainRyanrecept_TM4-6

RYR1 RYR2

2.78e-0431812IPR009460
DomainRyR

RYR1 RYR2

2.78e-0431812PF02026
Domain-

SHH DHH

2.78e-04318123.30.1380.10
DomainRR_TM4-6

RYR1 RYR2

2.78e-0431812PF06459
DomainHint_dom_N

SHH DHH

2.78e-0431812IPR003587
DomainHint_dom_C

SHH DHH

2.78e-0431812IPR003586
DomainRyan_recept

RYR1 RYR2

2.78e-0431812IPR013333
DomainROC_dom

MFHAS1 LRRK2

5.53e-0441812IPR020859
DomainROC

MFHAS1 LRRK2

5.53e-0441812PS51424
DomainHedgehog/Intein_dom

SHH DHH

5.53e-0441812IPR028992
Domain-

SHH DHH

5.53e-04418122.170.16.10
DomainLRRC8_Pannexin-like

LRRC8C LRRC8D

9.16e-0451812IPR021040
DomainPannexin_like

LRRC8C LRRC8D

9.16e-0451812PF12534
DomainRIH_assoc-dom

RYR1 RYR2

1.37e-0361812IPR013662
DomainTRP_2

TRPC4 TRPC5

1.37e-0361812PF08344
DomainIns145_P3_rec

RYR1 RYR2

1.37e-0361812PF08709
DomainTRP_dom

TRPC4 TRPC5

1.37e-0361812IPR013555
DomainRIH_assoc

RYR1 RYR2

1.37e-0361812PF08454
DomainRIH_dom

RYR1 RYR2

1.37e-0361812IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2

1.37e-0361812IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2

1.37e-0361812IPR015925
Domain-

RYR1 RYR2

1.37e-03618121.25.10.30
DomainRYDR_ITPR

RYR1 RYR2

1.37e-0361812PF01365
DomainLRRNT

LINGO3 BGN SLITRK2 TPBG

1.73e-03531814PF01462
DomainTRPC_channel

TRPC4 TRPC5

1.90e-0371812IPR002153
DomainZnF_UBR1

UBR5 UBR3

1.90e-0371812SM00396
DomainZF_UBR

UBR5 UBR3

1.90e-0371812PS51157
Domainzf-UBR

UBR5 UBR3

1.90e-0371812PF02207
DomainZnf_UBR

UBR5 UBR3

1.90e-0371812IPR003126
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

SHH DHH DISP2

2.55e-0571293MM15187
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

SHH DHH DISP2

4.05e-0581293M27444
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

SHH DHH LRP2

6.04e-0591293M47893
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MTMR12 PHF24 BEND3 HEATR5A ADCY6 RUSC2 ARFGEF3 LRFN2 KANSL1 RPAP1 UBR5 FNIP1 DISP2 LRRC7 SCRIB SPEN CLEC16A

6.69e-114071831712693553
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MAN2A2 PGAP3 MYCBP2 MFHAS1 NLRX1 RTTN MED14 AMBRA1 FBXL19 BCR STK11IP ABCA7 RYR1 PLEKHH3 TBC1D24 GGT7 KANSL1 RPAP1 TMCC2 DISP2 BRAT1 SPEN IQGAP3 EP300

4.74e-0911051832435748872
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MTMR12 DGKA L2HGDH AMBRA1 YTHDC2 COLGALT1 BCR DICER1 ADCY6 RUSC2 RPAP1 ANAPC2 IFT122 SCRIB RIOK2 CLEC16A IQGAP3 SORL1

1.22e-086501831838777146
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 DDX60 SYTL2 LRRK2 YTHDC2 RYR1 LRP2 SCRIB SPEN IQGAP3 SORL1

1.56e-082081831133230847
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

YTHDC2 BCR DICER1 ARFGEF3 UBR5 ARHGAP29 FNIP1 AKAP11 SCRIB

1.81e-06209183936779422
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 DICER1 ADCY6 UBR5 SPON1 TMCC2 AKAP11 SCRIB CLEC16A

3.32e-06225183912168954
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

TLK2 YTHDC2 PTK6 SPATA31D4 SPATA31D3 NYNRIN CCDC17 ICA1L SLC39A7

4.41e-06233183937704626
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

CAND2 MYCBP2 NLRX1 L2HGDH AMBRA1 CHD1L BCR STK11IP AAAS RPAP1 VPS51 BRAT1 CLEC16A IQGAP3

4.50e-066061831436538041
Pubmed

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.

LRRK2 PTK6 EP300

7.87e-068183326751287
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TBRG4 CAND2 SGSH SEC31A GTF3C3 GGT7 ARFGEF3 CNNM4 AAAS RPAP1 UBR5 ANAPC2 SCRIB TMEM143 VPS51 BRAT1 IQGAP3

1.12e-059421831731073040
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYCBP2 ARHGEF38 L2HGDH CHD1L BCR LRRC8D PTK6 DNAH1 ARFGEF3 CNNM4 LRFN2 INTS2 CLMN MICAL2 LRRC1 FNIP1 LRRC7 IFT122 TMEM143 CLEC16A ICA1L EP300

1.31e-0514891832228611215
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

SLC39A3 SEC31A PTK6 KCNQ4 CLK3 LTC4S VPS51 EP300 SLC39A7

1.71e-05276183928319085
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

TLK2 BEND3 BCR DICER1 UBR5 SLAIN1 IFT122 EP300

2.57e-05223183833187986
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TBRG4 CAND2 AMBRA1 BCR DICER1 TBC1D24 CNOT6 INTS2 ANAPC2 MED12L AKAP11 ACAP3

2.63e-055291831214621295
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

2.75e-052183217259277
Pubmed

The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway.

LRRC1 SCRIB

2.75e-052183231513346
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

2.75e-052183214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

2.75e-052183226009179
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

2.75e-052183232899693
Pubmed

The anaphase promoting complex is required for memory function in mice.

APC2 ANAPC2

2.75e-052183221191042
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

2.75e-052183222457348
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

2.75e-052183223677990
Pubmed

Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice.

SHH DHH

2.75e-052183224135022
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

2.75e-052183232033274
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

2.75e-052183215033925
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

2.75e-052183217624425
Pubmed

Identification of a novel in-frame deletion in KCNQ4 (DFNA2A) and evidence of multiple phenocopies of unknown origin in a family with ADSNHL.

KCNQ4 PCDH15

2.75e-052183223443030
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

2.75e-052183234899056
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

2.75e-052183217593972
Pubmed

Antigen receptor signals rescue B cells from TLR tolerance.

TLR7 BCR

2.75e-052183219648281
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

2.75e-052183226317356
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

2.75e-05218329687496
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

2.75e-052183230542613
Pubmed

Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity.

LRRK2 FBXL18

2.75e-052183227890708
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

2.75e-052183215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

2.75e-052183211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

2.75e-052183211673462
Pubmed

Dicer1 Ablation Impairs Responsiveness of Cerebellar Granule Neuron Precursors to Sonic Hedgehog and Disrupts Expression of Distinct Cell Cycle Regulator Genes.

SHH DICER1

2.75e-052183227600805
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

2.75e-052183225370123
Pubmed

AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera.

SHH ADCY6

2.75e-052183229903911
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

2.75e-052183218618700
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

2.75e-052183230038709
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC4 TRPC5 RYR1 RYR2

4.76e-0538183430786075
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

TBRG4 DPCD TRAPPC8 ARHGAP29 AKAP11 RIOK2 SMAD9

5.55e-05183183731932471
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TLK2 CRTC3 CAND2 MYCBP2 AMBRA1 FBXL19 BCR DICER1 ADCY6 TEFM CNOT6 CNNM4 CCDC154 IFT122 MINDY4 VPS51 IQGAP3 SORL1 SMAD9

7.53e-0513211831927173435
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

NLRX1 L2HGDH BCR STK11IP DICER1 GTF3C3 GGH CNNM4 AAAS CLMN FHOD1 LRRC1 AKAP11

7.66e-056861831328380382
Pubmed

[Hedgehog signaling pathway and its impact on development of cancer therapy].

SHH DHH

8.23e-053183218788453
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2

8.23e-053183218403125
Pubmed

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

TRPC4 TRPC5

8.23e-053183228790178
Pubmed

AC6 regulates the microtubule-depolymerizing kinesin KIF19A to control ciliary length in mammals.

SHH ADCY6

8.23e-053183232683324
Pubmed

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

SHH DHH

8.23e-053183219561611
Pubmed

Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.

APC2 ANAPC2

8.23e-053183212471060
Pubmed

The hedgehog signaling pathway in the mouse ovary.

SHH DHH

8.23e-053183217392501
Pubmed

Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.

TRPC4 TRPC5

8.23e-053183230755645
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2

8.23e-05318327876312
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

8.23e-053183224123915
Pubmed

Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.

RYR1 RYR2

8.23e-053183223278119
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2

8.23e-053183222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2

8.23e-053183210788707
Pubmed

Mettl3-mediated m6 A modification of Lrp2 facilitates neurogenesis through Ythdc2 and elicits antidepressant-like effects.

YTHDC2 LRP2

8.23e-053183235716070
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2

8.23e-05318327621815
Pubmed

Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.

ABCA7 SORL1

8.23e-053183228789839
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2

8.23e-053183210473538
Pubmed

Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.

TRPC4 TRPC5

8.23e-053183234199280
Pubmed

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.

SHH DHH

8.23e-053183219074837
Pubmed

Evolution of the hedgehog gene family.

SHH DHH

8.23e-05318328849902
Pubmed

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A.

RUSC1 RUSC2

8.23e-053183230262884
Pubmed

The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.

SHH DHH

8.23e-053183218063705
Pubmed

Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression.

DICER1 UBR5

8.23e-053183238280476
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2

8.23e-053183218434746
Pubmed

The world according to hedgehog.

SHH DHH

8.23e-05318329009843
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2

8.23e-05318329204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2

8.23e-053183221881589
Pubmed

Hedgehog signal transduction: from flies to vertebrates.

SHH DHH

8.23e-053183210579908
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2

8.23e-053183212213830
Pubmed

TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity.

TRPC4 TRPC5

8.23e-053183232359120
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2

8.23e-05318329242641
Pubmed

Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.

RYR1 RYR2

8.23e-053183223454728
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2

8.23e-053183225239916
Pubmed

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

TRPC4 TRPC5

8.23e-053183228325835
Pubmed

LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission.

LRRC1 SCRIB

8.23e-053183227321929
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2

8.23e-053183218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2

8.23e-053183211159936
Pubmed

Intracellular calcium release channel expression during embryogenesis.

RYR1 RYR2

8.23e-05318329986730
Pubmed

A new role for Hedgehogs in juxtacrine signaling.

SHH DHH

8.23e-053183224342078
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2

8.23e-05318327959768
Pubmed

The NLR gene family: a standard nomenclature.

NLRX1 NLRP13

8.23e-053183218341998
Pubmed

Comparative biological responses to human Sonic, Indian, and Desert hedgehog.

SHH DHH

8.23e-053183211472839
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2

8.23e-05318324600883
Pubmed

Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.

TRPC4 TRPC5

8.23e-053183230108272
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2

8.23e-05318327635066
Pubmed

LRP2/megalin is required for patterning of the ventral telencephalon.

SHH LRP2 SMAD9

9.23e-0517183315623804
Pubmed

Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.

TRPC4 TRPC5 RYR1

9.23e-0517183322411552
Pubmed

Notum attenuates Wnt/β-catenin signaling to promote tracheal cartilage patterning.

SHH LGI3 LRRC7

1.10e-0418183329428562
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

NLRX1 MED14 CHADL HID1 ANAPC2 PRKCH SPEN EP300

1.36e-04283183818854154
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LRRC8C PGAP3 USP22 DGKA PIDD1 GAL3ST2 PARVG RYR1 RPAP1 LRP2 LRRC7 SCRIB GP5

1.54e-047361831329676528
Pubmed

Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability.

SHH DHH

1.64e-044183233063110
Pubmed

Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.

TRPC4 TRPC5

1.64e-044183218261457
Pubmed

The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

TRPC4 TRPC5

1.64e-044183220164195
Pubmed

Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.

SHH DHH

1.64e-04418329053312
Cytoband9q21.32

SPATA31D4 SPATA31D1 SPATA31D3

5.76e-051918339q21.32
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

1.10e-0431102287
GeneFamilyVolume regulated anion channel subunits

LRRC8C LRRC8D

3.62e-04511021158
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR5 UBR3

7.55e-0471102785
GeneFamilyClassical BAR domain containing

ARHGEF38 ICA1L

1.00e-03811021292
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BCR PLEKHH3 PLEKHG6 FGD5 ACAP3 PHLPP2

1.63e-032061106682
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBRG4 GPR25 CHADL PLEKHH3 RPAP1 AKAP11 BRAT1 TMEM82 TRDMT1

3.76e-081701839d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

USP22 HEATR5A CHD1L GTF3C3 TBC1D24 MZF1 IFT122 ICA1L CFAP46

1.07e-071921839445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Mega-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

SLC39A3 L2HGDH CHD1L TSKU GGH IFT122 GPAT2 IQGAP3

1.15e-0618818388e80e0714883e5c5e372d933682c5b55ebef7e62
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HEATR5A GTF3C3 TBC1D24 MZF1 OXNAD1 IFT122 ICA1L CFAP46

1.19e-061891838c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MAN2A2 ABCA7 MICAL2 TMCC2 HBM ACKR1 EP300 TBCEL

1.40e-061931838be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAN2A2 CHADL ARFGEF3 CLMN LGI3 TMCC2 LRP2 SLAIN1

1.63e-06197183882b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-Treg|Bac-SEP / Disease, condition lineage and cell class

ST6GALNAC1 CCR10 L2HGDH SUOX CCDC154 OXNAD1 SLAIN1 VPS51

1.75e-061991838e0b6136e28b813299b7ffbe37f1cf830e60cd7d8
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

PLEKHH3 DHH MZF1 UCN ANAPC2 LTC4S ACKR1

3.68e-061551837a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

DDX60 GGT7 CNNM4 UCN TMEM143 EP300 TPBG

4.35e-061591837037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCelldroplet-Fat-SCAT-30m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC5 CYP27A1 PIGZ CD68 LTC4S RTN4RL2 SLC27A5

4.53e-06160183761eefe84c8e30d8a3812f5b48d26ed01739aa1ce
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 ARHGEF38 PIDD1 PIGZ CNNM4 FCGBP DISP2

6.75e-0617018379bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 ARHGEF38 PIDD1 PIGZ CNNM4 FCGBP DISP2

6.75e-0617018372c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

DMGDH CYP27A1 PLEKHG6 NYNRIN CD68 LRRC7 CCDC17

6.75e-061701837439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 ARHGEF38 HID1 ARFGEF3 FCGBP DISP2

7.02e-06171183748125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

DNHD1 COLGALT1 ABCA7 SLC26A1 DNAH1 FCGBP LPO

7.29e-061721837f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

TLK2 TBRG4 L2HGDH HID1 NYNRIN ARHGAP29 TMEM143

7.29e-061721837fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCell390C-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAN2A2 NLRX1 CHADL STK11IP FBXL18 LTC4S TMEM143

9.45e-0617918373edcd1356e49b1f5514c585861999e079ca5e579
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

MAN2A2 NLRX1 MED14 CHADL STK11IP FBXL18 TMEM143

9.45e-061791837e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HID1 BCR TBC1D24 C20orf141 DHH PRKCH FGD5

1.05e-051821837d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LRRC58 ADCY6 RYR2 KANSL1 UBR5 NYNRIN

1.30e-0518818376468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LRRC58 ADCY6 RYR2 KANSL1 UBR5 NYNRIN

1.30e-0518818377a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 LRRC58 ADCY6 RYR2 KANSL1 UBR5 NYNRIN

1.30e-0518818379cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

HEATR5A GTF3C3 TBC1D24 MZF1 IFT122 ICA1L CFAP46

1.30e-0518818378f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 SHH HID1 ARFGEF3 LRP2 SLAIN1 IQGAP3

1.35e-051891837c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C DHH LRRC1 PRKCH FGD5 LTC4S ACKR1

1.49e-051921837717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ ARFGEF3 FCGBP PLEKHG6

1.54e-051931837402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C BCR LRRC1 PRKCH FGD5 LTC4S ACKR1

1.54e-0519318377261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ ARFGEF3 FCGBP PLEKHG6

1.54e-0519318377ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 SYTL2 LRRK2 ARHGEF38 XKR4 CLMN ARHGAP29

1.59e-051941837e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 SYTL2 ARHGEF38 XKR4 CLMN ARHGAP29 CLEC16A

1.65e-051951837938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 ARHGEF38 HID1 PIGZ ARFGEF3 FCGBP

1.65e-0519518377ff04c45a02df01e3816f3c1d43585a93182a730
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 SYTL2 ARHGEF38 XKR4 CLMN ARHGAP29 CLEC16A

1.65e-051951837d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 ARHGEF38 HID1 PIGZ ARFGEF3 FCGBP

1.65e-05195183709605533aa5947bb2e5a6725c1ce89f79d330bf5
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

ST6GALNAC1 DGKA RYR1 TSKU FCGBP NYNRIN SORL1

1.76e-05197183778ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

CCR10 PAQR6 HID1 ADCY6 PLEKHH3 ARFGEF3 LRRC14B

1.76e-051971837a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

CCR10 PAQR6 HID1 ADCY6 PLEKHH3 ARFGEF3 LRRC14B

1.76e-05197183720822fce311326765b71337ce501ba44ea14f58f
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ FCGBP PLEKHG6 PTGDR2

1.82e-0519818379c5d7852f03468394e726c444cac92a043fc6d0e
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ FCGBP PLEKHG6 PTGDR2

1.82e-051981837f95f38cc747fb3549a791288bf8d0518c049ac96
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 ARHGEF38 TACC2 ARFGEF3 MICAL2 LGI3 LRP2

1.94e-052001837b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHADL ARFGEF3 CLMN LGI3 TMCC2 LRP2 SLAIN1

1.94e-052001837159377d904394d91e09913131e9a93e08189955a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHADL ARFGEF3 CLMN LGI3 TMCC2 LRP2 SLAIN1

1.94e-0520018370bfd41c12887479ceb62c3db0a3c3ba5007eb62b
ToppCellMS-CD4-CD8_2|MS / Condition, Cell_class and T cell subcluster

PTK6 CNNM4 MICAL2 SCRIB GPAT2 SORL1

3.54e-05149183608fb6be5599c5988890c851ce5ac6781c319948e
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC5 BTBD17 CD68 LTC4S RTN4RL2 SLC27A5

4.25e-05154183673de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC5 BTBD17 CD68 LTC4S RTN4RL2 SLC27A5

4.25e-05154183656fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 CAPN12 LRRK2 ARHGEF38 TACC2 FCGBP

4.74e-05157183631d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGAP3 HK3 TTC16 TLR7 SPATA31D3 CD68

4.74e-051571836c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGAP3 HK3 TTC16 TLR7 SPATA31D3 CD68

4.74e-0515718367fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGAP3 HK3 TTC16 TLR7 SPATA31D3 CD68

4.74e-0515718366b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

SYTL2 GAL3ST2 MFSD14A DISP2 LTC4S IQGAP3

5.45e-05161183644f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNHD1 HID1 MZF1 MICAL2 DISP2 SMAD9

5.84e-051631836b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 CAPN12 LRRK2 ARHGEF38 TACC2 HID1

5.84e-051631836e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNHD1 HID1 MZF1 MICAL2 DISP2 SMAD9

5.84e-0516318362913ccdd4613472cd82077d4993e1d9f8b223398
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-late_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPCD TMCC2 LTC4S HBM PTGDR2 TBCEL

6.46e-051661836b4e5466a33578103d197cf67f37e7ec88e09281f
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

HEATR5A MZF1 OXNAD1 IFT122 ICA1L CFAP46

6.46e-051661836a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBRG4 RUSC1 TLR7 PARVG BCR CD68

6.68e-051671836b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBRG4 RUSC1 TLR7 PARVG BCR CD68

6.68e-051671836e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ST6GALNAC1 CRTC3 DDX60 DGKA TMCC2 OXNAD1

6.90e-0516818365e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DMGDH DPCD PLEKHG6 NYNRIN LRRC7 CCDC17

7.61e-0517118367c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 SYTL2 ADCY6 PLEKHH3 ARHGAP29 TPBG

7.86e-0517218360be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY6 PLEKHH3 LRFN2 KCNQ4 RTN4RL2 TBCEL

8.11e-051731836d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY6 PLEKHH3 LRFN2 KCNQ4 RTN4RL2 TBCEL

8.11e-0517318363c852ffe22f4a5b632463086b08c669310684e80
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SHH ARFGEF3 FCGBP UCN SCRIB

8.64e-051751836019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SHH ARFGEF3 FCGBP UCN SCRIB

9.49e-0517818369099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 PIGZ FCGBP CLMN DISP2

9.78e-051791836c833ded1f9e87be2ba2037820d92a389560b711c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN12 LRRK2 XKR4 SPON1 LRP2 GP5

9.78e-05179183658ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TRPC4 HID1 RYR2 ARFGEF3 FCGBP SMAD9

1.01e-041801836a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellIIH-CD8-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

PIDD1 CNOT6 AAAS SPON1 IFT122 BRAT1

1.01e-041801836d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

LRRK2 ARHGEF38 TACC2 ARFGEF3 MICAL2 LRP2

1.01e-041801836198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellsevere-CD8+_T_naive|severe / disease stage, cell group and cell class

DNHD1 ZGRF1 TBC1D24 TEFM PTK6 OXNAD1

1.01e-04180183694fe530367b170777f4051a4034cff06d80dbb83
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

DNHD1 ZGRF1 TBC1D24 TEFM PTK6 OXNAD1

1.04e-04181183669eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAN2A2 MICAL2 TMCC2 HBM EP300 TBCEL

1.07e-0418218360c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PAQR6 CHADL XKR4 SLITRK2 NEUROG1 IQGAP3

1.07e-041821836f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

CCR10 HID1 PLEKHH3 ARFGEF3 CLMN TBCEL

1.10e-041831836ab5aaafcfd7b97330be6774be4c72611ca85257c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

CCR10 HID1 PLEKHH3 ARFGEF3 CLMN TBCEL

1.10e-041831836193bfb787c1b36c8fabf4b00fafb5b398de6b999
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PAQR6 CHADL XKR4 SLITRK2 NEUROG1 ZDHHC22

1.10e-041831836f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR6 BGN RUSC2 CDAN1 MICAL2 TPBG

1.10e-041831836ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CHADL ADCY6 RYR2 KCNQ4 MED12L GP5

1.10e-0418318369c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 DNAH1 ARFGEF3 SLITRK2 PCDH15 LRP2

1.14e-0418418362cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 DNAH1 ARFGEF3 SLITRK2 PCDH15 LRP2

1.14e-0418418362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ FCGBP SLAIN1

1.14e-041841836886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRRK2 ARHGEF38 TACC2 ARFGEF3 MICAL2 LRP2

1.14e-041841836369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 SYTL2 HID1 PIGZ FCGBP SLAIN1

1.14e-041841836936b39377eebea3961d702532779f6cd27953be7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 DNAH1 ARFGEF3 SLITRK2 PCDH15 LRP2

1.14e-041841836ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

RUSC1 ADCY6 GGH MED12L LTC4S GPAT2

1.14e-041841836030d5ef5e44e4d973862128fe01f7e8ef0092a06
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DHH ARHGAP29 PRKCH FGD5 MINDY4 ACKR1

1.17e-0418518360ab1be455f2cd883c9d1522ca78112c37833352e
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

BCR LRRC1 ARHGAP29 FGD5 ACKR1 SMAD9

1.17e-041851836f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MICAL2 TMCC2 MED12L HBM TBCEL PHLPP2

1.21e-041861836e5014443e9d6e25943308483e20d48b776ae5373
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MICAL2 TMCC2 MED12L HBM TBCEL PHLPP2

1.21e-041861836affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MICAL2 TMCC2 MED12L HBM TBCEL PHLPP2

1.21e-04186183640d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPC4 PAQR6 CHADL XKR4 SLITRK2 ZDHHC22

1.21e-0418618363113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C DHH PRKCH FGD5 LTC4S ACKR1

1.21e-04186183692092f11ecce22c14f244e42c499af0822977e6f
ToppCellControl-Epithelial_alveolar-AT_2-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST6GALNAC1 RFNG DNAH1 LGI3 SCRIB

1.22e-041171835c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

LRRC1 ARHGAP29 PRKCH FGD5 ACKR1 SMAD9

1.24e-0418718362d20193a6cacdfa4877457c97b0077408942186c
ToppCell10x5'v1-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CHADL ADCY6 RYR2 KCNQ4 MED12L GP5

1.24e-04187183634cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

BCR PCDH15 ARHGAP29 PRKCH FGD5 SMAD9

1.24e-0418718367876dcb4800c2e54874df3d933efb79307a64a97
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APC2 BTBD17 PAQR6 CHADL ZDHHC22 SEZ6

1.28e-0418818369fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

LRRC1 ARHGAP29 PRKCH FGD5 ACKR1 SMAD9

1.28e-041881836d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CHADL ADCY6 RYR2 KCNQ4 MED12L GP5

1.28e-041881836c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APC2 BTBD17 PAQR6 CHADL ZDHHC22 SEZ6

1.28e-041881836459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPCD MICAL2 TMCC2 HBM ACKR1 TBCEL

1.28e-0418818363467149de45b47a5015486ef94bec070e9c3ffc2
Diseaseneurodegenerative disease (implicated_via_orthology)

MTMR12 TRPC4 TRPC5 LRRK2 TBC1D24 UBR3 CLEC16A

2.76e-051451767DOID:1289 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

1.06e-0431762DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

1.06e-0431762DOID:8545 (implicated_via_orthology)
Diseaseprimary pulmonary hypertension (is_implicated_in)

RYR1 SMAD9

5.22e-0461762DOID:14557 (is_implicated_in)
Diseasebirth measurement, spontaneous preterm birth

SORL1 SMAD9

7.28e-0471762EFO_0006917, EFO_0006921
DiseaseMalignant neoplasm of breast

HK3 TRPC4 APC2 ARHGEF38 MED14 TACC2 TRAPPC8 BGN CNNM4 ARHGAP29 LRRC7 FGD5 SPEN CTU1 EP300 SORL1

7.39e-04107417616C0006142
Diseasebenign neoplasm (implicated_via_orthology)

LRRC1 SCRIB

9.67e-0481762DOID:0060072 (implicated_via_orthology)
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

SHH DHH

1.24e-0391762DOID:0050338 (implicated_via_orthology)
DiseaseNonsyndromic Deafness

TBC1D24 KCNQ4 PCDH15 STRC

1.42e-03811764C3711374
Diseasevisual epilepsy (is_implicated_in)

L2HGDH TBC1D24

1.88e-03111762DOID:11832 (is_implicated_in)
Diseasekidney cancer (implicated_via_orthology)

LRRC1 SCRIB

1.88e-03111762DOID:263 (implicated_via_orthology)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 LRRK2 PIDD1 RYR1 RIOK2

1.98e-031481765C0279702
Diseasenicotine dependence (implicated_via_orthology)

TRPC4 TRPC5

2.24e-03121762DOID:0050742 (implicated_via_orthology)
DiseaseAsthma, Aspirin-Induced

LTC4S PTGDR2

2.64e-03131762C1319853
DiseaseMetabolic Bone Disorder

CYP27A1 LRP2

3.07e-03141762C0005944
DiseaseArthritis, Psoriatic

FBXL19 CD68

3.07e-03141762C0003872
Diseaseearly cardiac repolarization measurement

MYCBP2 HBM

3.07e-03141762EFO_0004885
Diseasemean reticulocyte volume

FLOT2 NLRX1 RTTN BEND3 MAU2 ABCA7 TBC1D24 CNOT6 KANSL1 NYNRIN TMCC2 SLC27A5

3.17e-0379917612EFO_0010701
DiseaseOsteopenia

CYP27A1 LRP2

3.53e-03151762C0029453
Diseaseserum selenium measurement

DMGDH USP22 SHH

3.93e-03531763EFO_0005266
Disease2-hydroxyglutarate measurement

L2HGDH GAL3ST2

4.02e-03161762EFO_0021506
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

UBR5 ARHGAP29

4.02e-03161762C0334634
DiseaseIGFBP-3 measurement

MFHAS1 CLEC16A TMEM82

4.14e-03541763EFO_0004626
DiseaseDiffuse Large B-Cell Lymphoma

SEC31A SPEN EP300

4.36e-03551763C0079744
DiseaseEye Abnormalities

SHH IFT122

4.54e-03171762C0015393
DiseaseDrug habituation

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0013170
DiseaseDrug abuse

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0013146
DiseasePrescription Drug Abuse

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C4316881
DiseaseSubstance-Related Disorders

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0236969
DiseaseDrug Use Disorders

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0013222
DiseaseDrug Dependence

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C1510472
DiseaseSubstance Dependence

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0038580
DiseaseSubstance Use Disorders

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

CHD1L XKR4 PCDH15 PRKCH

5.06e-031151764C0029231
DiseaseSubstance abuse problem

CHD1L XKR4 PCDH15 PRKCH

5.22e-031161764C0740858
DiseaseIntellectual Disability

TLK2 APC2 RTTN L2HGDH GTF3C3 KANSL1 MED12L LRP2

5.57e-034471768C3714756
DiseaseCannabis use, age at onset

RYR2 LRRC7

5.66e-03191762EFO_0004847, EFO_0007585

Protein segments in the cluster

PeptideGeneStartEntry
ALHFSRPASLLLLLS

BTN2A3P

6

Q96KV6
LSILHANPQLLAAFI

EP300

2071

Q09472
GLRSLAQHPSALRFL

BRAT1

126

Q6PJG6
GSLFPHLSLRSEDLI

AAAS

126

Q9NRG9
RNLGLDSHFLLPTSD

CCDC17

371

Q96LX7
PTSAHLLQLALADLL

CCR10

76

P46092
LNFLADHRLFPALQS

CCDC116

301

Q8IYX3
SLLADRLLHQFSFSP

ANAPC2

521

Q9UJX6
LPEANLLTFLFLLDH

BCR

1171

P11274
TSRCLALFLLLNHPT

CALCR

6

P30988
LLTAVLLAFHAAPAR

ADCY6

161

O43306
FASHLQRLILTPLSA

ARHGEF38

411

Q9NXL2
SHAFQGLSLLLLLLT

GPR25

196

O00155
NRLLAELPASVHALT

FLOT2

396

Q14254
LLGLHSELFLELLSN

BTBD17

86

A6NE02
LENRPLAATSSHLLL

CFAP46

1346

Q8IYW2
AQRITLAEALLHPFF

CLK3

606

P49761
ARARDLPALAAALAH

ACAP3

676

Q96P50
PLLLALFCHQATRTL

ACKR1

301

Q16570
AVSLELPDILNSLHF

AKAP11

76

Q9UKA4
VLRALSSAVPANLHL

DNHD1

1806

Q96M86
LLRSPLFSILNGLHL

DNHD1

1911

Q96M86
ASLAFHPTAQLLLIA

AMBRA1

141

Q9C0C7
PLLDVDHTSSRLNLL

DICER1

986

Q9UPY3
LSGHLPALSSRLDLQ

CCDC154

406

A6NI56
LLHFLLDRDFLSPQT

DISP2

411

A7MBM2
ELATLSNLFLAEPHL

CDAN1

1191

Q8IWY9
GPLFLLFTLLLQHRS

ABCA7

1741

Q8IZY2
DASLRLLLRHAPQLS

FBXL19

586

Q6PCT2
LLLRHAPQLSALDLS

FBXL19

591

Q6PCT2
ALADLPSLEFLRLNA

RTN4RL2

246

Q86UN3
HLLVALAKRFQPDLS

PARVG

141

Q9HBI0
VNARSLLHLLSSFSP

RFNG

151

Q9Y644
GNFASRLLVHLFPEL

BEND3

571

Q5T5X7
PAVHLDLLSLRLQAA

CD68

286

P34810
LSLESRLFHSLPQLR

LRTM1

111

Q9HBL6
RLFHSLPQLRELDLS

LRTM1

116

Q9HBL6
PLARSHVALLSAAFF

GPR6

221

P46095
PETLFNISRFLLHSL

IFT122

971

Q9HBG6
RLSLLLSDSPNLLAA

MED12L

301

Q86YW9
HNLNAALDALRSVLP

NEUROG1

106

Q92886
SFNRLAHLPDSLSCL

MFHAS1

166

Q9Y4C4
LASARALILRHPSLS

L2HGDH

61

Q9H9P8
RLSSLFPFALLQRHS

MTMR12

701

Q9C0I1
LHSLRTLAVDENFLP

LRRC7

321

Q96NW7
SILPSFRELALLFEH

KCNQ4

371

P56696
NFPELLSLRTALILH

DDX60

96

Q8IY21
NLSDSLARGRLHPDL

GGT7

586

Q9UJ14
LLAHFLPAALRAALL

LTC4S

126

Q16873
HLPALLASLILLQAA

LPO

6

P22079
GSLSFLPTLRELHLD

BGN

271

P21810
LGLLSENCLHSPRLA

FGD5

1001

Q6ZNL6
LHSALLRLLATNYPH

INTS2

706

Q9H0H0
LEVDNVPRHLSLALF

DGKA

61

P23743
HPLLSQSYELRAELL

KANSL1

111

Q7Z3B3
VLLHFQDPALQLSDL

LRRK2

1581

Q5S007
HNETLAALRAPLDLT

LINGO3

511

P0C6S8
FRADSLSPSQLLHVL

LRRC14B

191

A6NHZ5
LLTERIHLRNPSAAF

GGCT

26

O75223
IFALSNSLRSLHLDP

LRP2

2391

P98164
AALALARAAREHPSL

NLRX1

851

Q86UT6
LLTGFLFASHLPERL

PAQR6

231

Q6TCH4
LAAHRRLLEETLAPF

HK3

476

P52790
LHLALSDLLASASLP

PTGDR2

71

Q9Y5Y4
SLFLFRLGLAPQIHD

IQGAP3

146

Q86VI3
SLSLHNNLLTYLPRE

LRRC58

216

Q96CX6
AGNRLLHLPLSLTAL

LRRC1

366

Q9BTT6
ALLVALFIPEHTNLS

MFSD14A

441

Q96MC6
LASLARDALVHARLP

MED14

136

O60244
RLHLNEAVSFLSLPE

PTK6

136

Q13882
INPLLSILRHAADLL

OXNAD1

181

Q96HP4
LRDPNSFLLIHLTEF

PLEKHG6

466

Q3KR16
ALHPFTGELSLLRSL

PCDH15

866

Q96QU1
LLRQLPASNFNSLHF

ARHGAP29

806

Q52LW3
ALTLLLLAGFLHSDL

GAL3ST2

21

Q9H3Q3
ALPALDAALASLRNL

DNAH1

2916

Q9P2D7
PLLRLKAAHASLSND

APC2

911

O95996
LQALLSIALEPARAH

CAPN12

571

Q6ZSI9
LLILSPFLQETDHRF

HEATR5A

721

Q86XA9
LLLSLAVEPLTANFH

GGH

181

Q92820
AFAPLRLLHALGALL

DHH

356

O43323
ALPFQLDSLLHAHLS

FCGBP

4561

Q9Y6R7
NASALHPSLRLFSLS

CRTC3

356

Q6UUV7
NALREFLTSDLSPHL

FNDC11

46

Q9BVV2
FLPALITAVLTNHLA

FNIP1

451

Q8TF40
LVHSAERLALAPAAR

CTU1

266

Q7Z7A3
HSARLFIQSLEGLLP

ARFGEF3

671

Q5TH69
DRHQLPLDDALLSFA

DPCD

146

Q9BVM2
SASELHKLLQPFLLR

CHD1L

246

Q86WJ1
LHFLLASGQLSPREA

CYP27A1

311

Q02318
LTHLAQLSAELLPVF

GPAT2

536

Q6NUI2
LVSFLTFDLLHRPAG

C20orf141

76

Q9NUB4
HPSLFAELDAALLNA

C1orf112

431

Q9NSG2
DSIRLLDHLFANVIP

DMGDH

546

Q9UI17
SSLPCDFHLLNLRTL

MAN2A2

1046

P49641
SLTLSRNHLAFLPSA

GP5

246

P40197
RNHLAFLPSALFLHS

GP5

251

P40197
FLPSALFLHSHNLTL

GP5

256

P40197
LRAALSPLADLHALV

HBM

76

Q6B0K9
LAPALRARLTHFLDQ

FHOD1

921

Q9Y613
ALRALPSLFSLHLQD

CHADL

516

Q6NUI6
IALLARNAAHALPTT

COLGALT1

56

Q8NBJ5
FSLRNLHAFSVEPLL

COLGALT1

541

Q8NBJ5
LAHSSRFLPSQLFDL

ICA1L

391

Q8NDH6
LQPILAEALHILASF

CAND2

646

O75155
PRLFSNHAAQLHTLL

MAU2

371

Q9Y6X3
DPRLHNFLELAESIL

RYR1

4156

P21817
VDPLHQLILLFSRTA

RYR2

3661

Q92736
HTFILSAPAQLGLLR

PKD1L1

1846

Q8TDX9
LIPSDHFSLFAQLEL

CNOT6

526

Q9ULM6
LPHLCSVLLAFARLN

TBRG4

366

Q969Z0
ELERIPHAIFSLSNL

LRRC8D

646

Q7L1W4
AFNILTRHLDLDPLD

MICAL2

31

O94851
FLRLSTHEDPQLLEA

PIDD1

66

Q9HB75
LPLLHLAFRASSTDA

NYNRIN

1741

Q9P2P1
QHPAVVSAFRALLLL

PGAP3

191

Q96FM1
LQPLSVLTFHLDLLF

RUSC1

651

Q9BVN2
LPFSLDLLFQHRLLQ

RUSC2

1166

Q8N2Y8
ELLLRHSANPLLDLL

RTTN

1171

Q86VV8
CLDLPLLRGSHLNSF

SYTL2

801

Q9HCH5
SLRLLSALRFLNLSH

STK11IP

181

Q8N1F8
HTPTNFLLLSLALAD

TAAR5

66

O14804
LLALALPLAAALAFS

SPON1

16

Q9HCB6
SIPFRAADLLLHSKA

SORL1

201

Q92673
TNSFLHILDILPRLQ

TRDMT1

96

O14717
ELPFLFEQAHALLLR

PLEKHH3

511

Q7Z736
AFAPFRLAHALLAAL

SHH

376

Q15465
RLAHALLAALAPART

SHH

381

Q15465
HLLRKAPQDSSLAAI

TMCC2

196

O75069
AFLRHLTLAQLPSVL

FBXL18

531

Q96ME1
EHARPLAESLLLAIA

HID1

136

Q8IV36
LSLPSNVFRFVLLTH

SLITRK2

171

Q9H156
GTLPILRLAHFFLLN

RNF6

581

Q9Y252
LRSRAASAAAAPHLL

SLAIN1

46

Q8ND83
LFLPNLTLFLDSRHF

ST6GALNAC1

296

Q9NSC7
SPVRLLSLAFALSAH

SLC39A3

166

Q9BRY0
ISFLSHDIPALLERQ

SPATA31D4

401

Q6ZUB0
FSHPSLCLRSLQALL

MYCBP2

216

O75592
LSIQNSSLFPILLHF

TEFM

236

Q96QE5
PDGFTQLRSLAHLAL

SCRIB

121

Q14160
PDFLSHESLLLLQQL

PHF24

266

Q9UPV7
ATPHLDALARRSLLF

SGSH

46

P51688
LLALTPLHQAALAER

STRC

1291

Q7RTU9
LLAKFRSASLHSEPL

SMAD9

156

O15198
APLHLDARISLSTLQ

GTF3C3

486

Q9Y5Q9
APALGAHSLLRLTLA

TLK2

386

Q86UE8
FSIAQDALHIPRLLE

CLMN

251

Q96JQ2
NDVLTDHLLNRLFLP

CLEC16A

276

Q2KHT3
ISPQLLLAAHRFLAT

CNNM4

546

Q6P4Q7
ADRLSPFLAARHFNL

TBC1D24

476

Q9ULP9
HALLRKLQFLFELPS

VPS51

171

Q9UID3
ISFLSHDIPALLERQ

SPATA31D3

401

P0C874
VQALTHTPLLRDFFL

USP22

191

Q9UPT9
ARLFSPALLHGALFL

ZDHHC22

41

Q8N966
LPIAASSSLDAHIRL

WDR61

76

Q9GZS3
SHFSILFSLQPGLLR

MINDY4

676

Q4G0A6
ESHLSRLAPDLLASI

SPEN

3636

Q96T58
QLLRLLIQEFHSSPA

TMEM143

81

Q96AN5
DLQHNALTRLPDTLF

PHLPP2

576

Q6ZVD8
VLLALAPLFHDLQRS

SLC26A1

426

Q9H2B4
PHGLSLAAAALALTL

SLC27A5

61

Q9Y2P5
NSPRHRSLLQILLSF

SLC39A7

161

Q92504
PVNISFLSHDILALL

SPATA31D1

401

Q6ZQQ2
HLLATFLESAPQLVL

XKR4

306

Q5GH76
SLLALLAHGLSLEAP

SEZ6

11

Q53EL9
SADALLSRLAHPVSL

TACC2

2641

O95359
LSLSDHLLRATLNLL

USP9Y

2151

O00507
LSAFSHQEARFLIPL

PIGZ

381

Q86VD9
LAQLDPSLVAFLRSH

RPAP1

251

Q9BWH6
APHRTLNLLLSLGLA

TMEM82

146

A0PJX8
LHFLPSLIQLDLSFN

TLR7

336

Q9NYK1
HLIALSSLNREFRPF

RIOK2

451

Q9BVS4
LHFTLEPEAASLLLQ

YTHDC2

1111

Q9H6S0
LPFLRITSLLQHHLF

UBR3

1651

Q6ZT12
SLKARTLPDDLHFLN

ZGRF1

1026

Q86YA3
LTRLNHLSFAELLKP

TRAPPC8

31

Q9Y2L5
GAFEHLPSLRQLDLS

TPBG

136

Q13641
QSLSLSLDDLHNFPR

SUOX

241

P51687
VLLFSRALHLDPQLV

TTC16

81

Q8NEE8
LRLISLFTANSHLGP

TRPC5

491

Q9UL62
LRFASSPLRVLENHA

SEC31A

246

O94979
IPLDTAHLDLSSNRL

TSKU

56

Q8WUA8
RRDNPSLSIDLTFHL

UCN

81

P55089
SLARLFPNLRSISLH

TBCEL

221

Q5QJ74
RLISLFTANSHLGPL

TRPC4

491

Q9UBN4
TLPNSRGEHLLLFLV

UBR5

1266

O95071
ILSLARNHPFLTQLF

PRKCH

406

P24723
LERIPHAVFSLLSLQ

LRRC8C

601

Q8TDW0
SLRSLHLDSNRLPSL

LRFN2

101

Q9ULH4
DGAFSHLPLLQFLLL

LGI3

81

Q8N145
RAADPLNLSFLLDEH

NLRP13

61

Q86W25
FAHALLLPSDLRSEQ

MZF1

301

P28698