Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RNF7 RNF168 UBE3D TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL ASB4 DTX3L TNFAIP3 UHRF2 RFPL3 MAP3K1 TRIM51G	7.59e-11	473	82	16	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RNF7 RNF168 UBE3D TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL ASB4 DTX3L TNFAIP3 UHRF2 RFPL3 MAP3K1 TRIM51G	2.43e-10	512	82	16	GO:0019787
GeneOntologyMolecularFunction	acyltransferase activity	KMT2C RNF7 RNF168 UBE3D TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL ASB4 DTX3L TNFAIP3 UHRF2 CREBBP EP300 RFPL3 MAP3K1 TRIM51G	2.46e-10	775	82	19	GO:0016746
GeneOntologyMolecularFunction	aminoacyltransferase activity	RNF7 RNF168 UBE3D TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL ASB4 DTX3L TNFAIP3 UHRF2 RFPL3 MAP3K1 TRIM51G	4.25e-10	532	82	16	GO:0016755
GeneOntologyMolecularFunction	zinc ion binding	TRIM66 RNF7 DDAH1 KDM5A TRIM9 RBBP6 TRIM62 PHF14 TRIM71 KDM2A ZNFX1 UPF1 TNFAIP3 CREBBP EP300 SEC23B MAP3K1 TRIM51G KPNB1	2.50e-09	891	82	19	GO:0008270
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RNF7 RNF168 UBE3D TRIM9 RBBP6 TRIM62 TRIM71 RFFL ASB4 DTX3L UHRF2 RFPL3 TRIM51G	3.70e-09	372	82	13	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RNF7 RNF168 UBE3D TRIM9 RBBP6 TRIM62 TRIM71 RFFL ASB4 DTX3L UHRF2 RFPL3 TRIM51G	8.29e-09	398	82	13	GO:0061659
GeneOntologyMolecularFunction	transition metal ion binding	TRIM66 DPYD RNF7 DDAH1 KDM5A TRIM9 RBBP6 TRIM62 PHF14 TRIM71 KDM2A ZNFX1 UPF1 TNFAIP3 CREBBP EP300 PPM1N SEC23B MAP3K1 TRIM51G KPNB1	8.77e-09	1189	82	21	GO:0046914
GeneOntologyMolecularFunction	histone modifying activity	KMT2C SETD2 RNF168 KDM5A KDM2A DTX3L CREBBP EP300	4.55e-06	229	82	8	GO:0140993
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	1.67e-05	2	82	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	1.67e-05	2	82	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	4.98e-05	3	82	2	GO:0043993
GeneOntologyMolecularFunction	neuregulin binding	ERBB4 ITGB4	2.47e-04	6	82	2	GO:0038132
GeneOntologyMolecularFunction	SMAD binding	USP9X USP9Y CREBBP EP300	4.34e-04	86	82	4	GO:0046332
GeneOntologyMolecularFunction	histone binding	RNF168 KDM5A PHF14 DTX3L UHRF2 NPM3	7.78e-04	265	82	6	GO:0042393
GeneOntologyMolecularFunction	ADP binding	MAT1A MYO18A ATP1A1	1.01e-03	48	82	3	GO:0043531
GeneOntologyMolecularFunction	histone ubiquitin ligase activity	RNF168 DTX3L	1.07e-03	12	82	2	GO:0140852
GeneOntologyMolecularFunction	co-SMAD binding	USP9X USP9Y	1.07e-03	12	82	2	GO:0070410
GeneOntologyMolecularFunction	STAT family protein binding	DTX3L EP300	1.26e-03	13	82	2	GO:0097677
GeneOntologyMolecularFunction	transcription coactivator binding	ZBTB49 CREBBP EP300	1.42e-03	54	82	3	GO:0001223
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	CREBBP EP300	1.69e-03	15	82	2	GO:0010484
GeneOntologyMolecularFunction	K63-linked deubiquitinase activity	USP9X TNFAIP3	1.93e-03	16	82	2	GO:0061578
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP EP300	3.33e-03	21	82	2	GO:0042975
GeneOntologyMolecularFunction	p53 binding	RFFL CREBBP EP300	3.92e-03	77	82	3	GO:0002039
GeneOntologyBiologicalProcess	protein ubiquitination	RNF7 RNF168 UBE3D TRIM9 RBBP6 MTOR RNF141 USP9X TRIM62 TRIM71 CENPS RFFL ASB4 DTX3L TNFAIP3 UHRF2 RFPL3 MAP3K1 TRIM51G	3.07e-10	811	82	19	GO:0016567
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	RNF7 RNF168 UBE3D TRIM9 RBBP6 MTOR RNF141 USP9X TRIM62 TRIM71 CENPS RFFL ASB4 DTX3L TNFAIP3 UHRF2 RFPL3 MAP3K1 TRIM51G	1.53e-09	893	82	19	GO:0032446
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	RNF7 RNF168 UBE3D TRIM9 RBBP6 MTOR RNF141 USP9X TRIM62 TRIM71 CENPS RFFL ASB4 DTX3L TNFAIP3 USP9Y UHRF2 RFPL3 MAP3K1 TRIM51G	1.77e-09	1009	82	20	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	RNF7 RNF168 UBE3D TRIM9 RBBP6 MTOR RNF141 USP9X TRIM62 TRIM71 CENPS RFFL ASB4 DTX3L TNFAIP3 USP9Y UHRF2 RFPL3 MAP3K1 TRIM51G	5.13e-09	1074	82	20	GO:0043687
GeneOntologyBiologicalProcess	protein autoubiquitination	UBE3D RNF141 TRIM71 ASB4 DTX3L UHRF2	6.70e-07	78	82	6	GO:0051865
GeneOntologyBiologicalProcess	protein polyubiquitination	RNF168 UBE3D TRIM62 TRIM71 RFFL DTX3L TNFAIP3 RFPL3 MAP3K1	2.20e-06	289	82	9	GO:0000209
GeneOntologyBiologicalProcess	chromatin organization	KMT2C SETD2 MMS22L RNF168 KDM5A PHF14 KDM2A ZNFX1 DTX3L UHRF2 OGG1 CREBBP EP300 NPM3	1.08e-05	896	82	14	GO:0006325
GeneOntologyBiologicalProcess	regulation of protein localization	SETD2 ERBB4 FBN1 MALRD1 RNF168 KALRN MTOR CEP290 MYO18A DTX3L ITGB1 CREBBP EP300 RFPL3 TXN	2.19e-05	1087	82	15	GO:0032880
GeneOntologyBiologicalProcess	regulation of cellular response to heat	MTOR CREBBP EP300	3.27e-05	16	82	3	GO:1900034
GeneOntologyBiologicalProcess	chromatin remodeling	KMT2C SETD2 RNF168 KDM5A KDM2A ZNFX1 DTX3L UHRF2 OGG1 CREBBP EP300 NPM3	3.49e-05	741	82	12	GO:0006338
GeneOntologyBiologicalProcess	protein-DNA complex organization	KMT2C SETD2 MMS22L RNF168 KDM5A PHF14 KDM2A ZNFX1 DTX3L UHRF2 OGG1 CREBBP EP300 NPM3	3.61e-05	999	82	14	GO:0071824
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process	RNF7 RNF168 UBE3D TRIM9 RBBP6 USP9X TRIM71 RFFL DTX3L TNFAIP3 MAP3K1	4.47e-05	640	82	11	GO:0006511
GeneOntologyBiologicalProcess	modification-dependent protein catabolic process	RNF7 RNF168 UBE3D TRIM9 RBBP6 USP9X TRIM71 RFFL DTX3L TNFAIP3 MAP3K1	5.21e-05	651	82	11	GO:0019941
GeneOntologyBiologicalProcess	modification-dependent macromolecule catabolic process	RNF7 RNF168 UBE3D TRIM9 RBBP6 USP9X TRIM71 RFFL DTX3L TNFAIP3 MAP3K1	5.58e-05	656	82	11	GO:0043632
GeneOntologyBiologicalProcess	developmental growth	CCN4 KMT2C EYS ERBB4 RBBP6 MTOR USP9X SLIT3 EIF4G2 KDM2A SLITRK6 ITGB1 EP300	5.90e-05	911	82	13	GO:0048589
GeneOntologyBiologicalProcess	positive regulation of cell growth involved in cardiac muscle cell development	CCN4 MTOR EP300	6.58e-05	20	82	3	GO:0061051
GeneOntologyBiologicalProcess	positive regulation of cardiac muscle tissue growth	CCN4 ERBB4 MTOR EP300	7.28e-05	56	82	4	GO:0055023
GeneOntologyBiologicalProcess	regulation of cellular localization	SETD2 ERBB4 FBN1 MALRD1 RNF168 KALRN MTOR CEP290 MYO18A DTX3L ITGB1 CREBBP EP300 RFPL3 TXN	7.62e-05	1212	82	15	GO:0060341
GeneOntologyBiologicalProcess	N-terminal peptidyl-lysine acetylation	CREBBP EP300	9.32e-05	4	82	2	GO:0018076
GeneOntologyBiologicalProcess	positive regulation of heart growth	CCN4 ERBB4 MTOR EP300	9.55e-05	60	82	4	GO:0060421
GeneOntologyBiologicalProcess	DNA damage response	SETD2 MMS22L RNF168 RBBP6 MTOR USP9X KDM2A CENPS DTX3L UPF1 OGG1 CREBBP EP300	9.92e-05	959	82	13	GO:0006974
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	FBN1 USP9X USP9Y ITGB1 CREBBP EP300 MAP3K1	1.15e-04	276	82	7	GO:0007179
GeneOntologyBiologicalProcess	response to light stimulus	EYS RNF168 MTOR OGG1 ITGB1 CREBBP EP300 TAFA2	1.39e-04	382	82	8	GO:0009416
GeneOntologyBiologicalProcess	regulation of muscle atrophy	MTOR EP300	1.55e-04	5	82	2	GO:0014735
GeneOntologyBiologicalProcess	response to radiation	EYS RNF168 MTOR OGG1 ITGB1 CREBBP EP300 TAFA2 TXN	1.72e-04	503	82	9	GO:0009314
GeneOntologyBiologicalProcess	positive regulation of dendritic spine development	KALRN MTOR EIF4G2 CREBBP	1.74e-04	70	82	4	GO:0060999
GeneOntologyBiologicalProcess	developmental cell growth	CCN4 MTOR USP9X SLIT3 EIF4G2 ITGB1 EP300	1.96e-04	301	82	7	GO:0048588
GeneOntologyBiologicalProcess	heart development	CCN4 SETD2 ERBB4 FBN1 MTOR CEP290 SLIT3 EIF4G2 KDM2A ITGB1 EP300	1.97e-04	757	82	11	GO:0007507
GeneOntologyBiologicalProcess	axon extension	USP9X SLIT3 EIF4G2 ITGB1 EP300	2.03e-04	135	82	5	GO:0048675
GeneOntologyBiologicalProcess	positive regulation of organ growth	CCN4 ERBB4 MTOR EP300	2.05e-04	73	82	4	GO:0046622
GeneOntologyBiologicalProcess	DNA repair	SETD2 MMS22L RNF168 USP9X KDM2A CENPS DTX3L UPF1 OGG1 CREBBP	2.44e-04	648	82	10	GO:0006281
GeneOntologyBiologicalProcess	double-strand break repair	SETD2 MMS22L RNF168 KDM2A DTX3L OGG1 CREBBP	3.07e-04	324	82	7	GO:0006302
GeneOntologyBiologicalProcess	canonical NF-kappaB signal transduction	TRIM62 MYO18A TNFAIP3 CREBBP EP300 PPM1N RFPL3	3.43e-04	330	82	7	GO:0007249
GeneOntologyBiologicalProcess	epigenetic regulation of gene expression	RNF168 KDM5A KDM2A ZNFX1 UHRF2 OGG1 EP300	3.43e-04	330	82	7	GO:0040029
GeneOntologyBiologicalProcess	protein localization to organelle	SETD2 MMS22L ERBB4 VPS13D KALRN MTOR USP9X DTX3L TNFAIP3 CREBBP EP300 KPNB1 TXN	3.51e-04	1091	82	13	GO:0033365
GeneOntologyBiologicalProcess	proteolysis involved in protein catabolic process	RNF7 RNF168 UBE3D TRIM9 RBBP6 USP9X TRIM71 RFFL DTX3L TNFAIP3 MAP3K1	3.60e-04	812	82	11	GO:0051603
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	FBN1 USP9X USP9Y ITGB1 CREBBP EP300 MAP3K1	3.82e-04	336	82	7	GO:0071560
GeneOntologyBiologicalProcess	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	USP9X TNFAIP3	4.30e-04	8	82	2	GO:0071947
GeneOntologyBiologicalProcess	response to transforming growth factor beta	FBN1 USP9X USP9Y ITGB1 CREBBP EP300 MAP3K1	4.32e-04	343	82	7	GO:0071559
GeneOntologyBiologicalProcess	regulation of cell growth involved in cardiac muscle cell development	CCN4 MTOR EP300	4.62e-04	38	82	3	GO:0061050
GeneOntologyBiologicalProcess	positive regulation of molecular function	RNF7 ERBB4 FBN1 KALRN MTOR USP9X TRIM62 DTX3L ITGB1 CREBBP EP300 PREX2 RFPL3 MAP3K1 TXN	4.62e-04	1430	82	15	GO:0044093
GeneOntologyBiologicalProcess	circadian rhythm	DPYD KDM5A MTOR USP9X KDM2A EP300	4.64e-04	248	82	6	GO:0007623
GeneOntologyBiologicalProcess	multicellular organism growth	KMT2C RBBP6 MTOR KDM2A SLITRK6 EP300	4.74e-04	249	82	6	GO:0035264
GeneOntologyBiologicalProcess	regulation of dendritic spine development	KALRN MTOR EIF4G2 CREBBP	4.77e-04	91	82	4	GO:0060998
GeneOntologyBiologicalProcess	rhythmic process	DPYD KDM5A MTOR USP9X KDM2A CREBBP EP300	5.76e-04	360	82	7	GO:0048511
GeneOntologyBiologicalProcess	regulation of cardiac muscle tissue growth	CCN4 ERBB4 MTOR EP300	6.81e-04	100	82	4	GO:0055021
GeneOntologyBiologicalProcess	intracellular protein transport	VPS13D VPS39 USP9X CEP290 RFFL ITGB1 EP300 SEC23B KPNB1 TXN	6.91e-04	740	82	10	GO:0006886
GeneOntologyBiologicalProcess	establishment of mitotic spindle localization	INSC ITGB1 KPNB1	7.13e-04	44	82	3	GO:0040001
GeneOntologyBiologicalProcess	regulation of heart growth	CCN4 ERBB4 MTOR EP300	8.77e-04	107	82	4	GO:0060420
GeneOntologyBiologicalProcess	regulation of viral process	TRIM62 ZNFX1 CREBBP RFPL3 MAP3K1	8.80e-04	186	82	5	GO:0050792
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	3.13e-05	2	29	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	3.13e-05	2	29	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	3.13e-05	2	29	2	HP:0001042
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	9.36e-05	3	29	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	9.36e-05	3	29	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	9.36e-05	3	29	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	9.36e-05	3	29	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	9.36e-05	3	29	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	9.36e-05	3	29	2	HP:0005895
HumanPheno	Skin appendage neoplasm	CREBBP EP300 SEC23B	1.28e-04	18	29	3	HP:0012842
HumanPheno	Autistic behavior	KMT2C DPYD SETD2 MTOR USP9X CEP290 ZNFX1 ATP1A1 CREBBP NDUFS1 EP300 SEC23B	1.67e-04	678	29	12	HP:0000729
HumanPheno	Trichiasis	CREBBP EP300	1.86e-04	4	29	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	1.86e-04	4	29	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	1.86e-04	4	29	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	1.86e-04	4	29	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	1.86e-04	4	29	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	1.86e-04	4	29	2	HP:0031207
HumanPheno	Deep plantar creases	MTOR CREBBP EP300	2.06e-04	21	29	3	HP:0001869
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	3.10e-04	5	29	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	3.10e-04	5	29	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	3.10e-04	5	29	2	HP:0030421
HumanPheno	Abnormality of the plantar skin of foot	DSG1 MTOR ITGB4 CREBBP EP300 SEC23B	3.27e-04	171	29	6	HP:0100872
HumanPheno	Minor feet anomalies	MTOR CREBBP EP300	3.95e-04	26	29	3	HP:0010613
HumanPheno	Abnormal feet morphology	MTOR CREBBP EP300	3.95e-04	26	29	3	HP:0010611
HumanPheno	Diagnostic behavioral phenotype	KMT2C DPYD SETD2 MTOR USP9X CEP290 ZNFX1 ATP1A1 CREBBP NDUFS1 EP300 SEC23B	4.24e-04	747	29	12	HP:0025783
HumanPheno	Large foramen magnum	CREBBP EP300	4.63e-04	6	29	2	HP:0002700
HumanPheno	Smooth philtrum	DYM FBN1 MTOR USP9X CREBBP EP300	5.00e-04	185	29	6	HP:0000319
HumanPheno	Prominent forehead	DPYD SETD2 FBN1 MTOR USP9X CREBBP EP300	5.05e-04	261	29	7	HP:0011220
Domain	Znf_RING/FYVE/PHD	TRIM66 KMT2C RNF7 RNF168 KDM5A TRIM9 RBBP6 RNF141 TRIM62 PHF14 TRIM71 KDM2A RFFL DTX3L UHRF2 RNF17 RFPL3 MAP3K1	1.06e-12	459	82	18	IPR013083
Domain	-	TRIM66 KMT2C RNF7 RNF168 KDM5A TRIM9 RBBP6 RNF141 TRIM62 PHF14 TRIM71 KDM2A RFFL DTX3L UHRF2 RFPL3 MAP3K1	8.55e-12	449	82	17	3.30.40.10
Domain	ZF_RING_2	KMT2C RNF7 RNF168 TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL DTX3L UHRF2 RNF17 RFPL3 MAP3K1	4.25e-11	298	82	14	PS50089
Domain	RING	KMT2C RNF7 RNF168 TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL DTX3L UHRF2 RNF17 RFPL3 MAP3K1	5.78e-11	305	82	14	SM00184
Domain	Znf_RING	KMT2C RNF7 RNF168 TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL DTX3L UHRF2 RNF17 RFPL3 MAP3K1	1.39e-10	326	82	14	IPR001841
Domain	ZF_RING_1	RNF168 TRIM9 RBBP6 RNF141 TRIM62 TRIM71 RFFL DTX3L UHRF2 RNF17 RFPL3 MAP3K1	5.12e-09	291	82	12	PS00518
Domain	Znf_PHD-finger	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	1.28e-06	79	82	6	IPR019787
Domain	ARM-type_fold	DOCK2 ZYG11A MTOR INSC USP9X EIF4G2 ZNFX1 USP9Y MAP3K1 KPNB1	2.28e-06	339	82	10	IPR016024
Domain	PHD	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	2.59e-06	89	82	6	SM00249
Domain	Znf_PHD	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	2.94e-06	91	82	6	IPR001965
Domain	Znf_FYVE_PHD	TRIM66 KMT2C KDM5A PHF14 KDM2A RFFL UHRF2	3.76e-06	147	82	7	IPR011011
Domain	ZF_PHD_2	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	3.79e-06	95	82	6	PS50016
Domain	ZF_PHD_1	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	4.03e-06	96	82	6	PS01359
Domain	zf-C3HC4	RNF7 RNF168 TRIM9 RNF141 TRIM62 DTX3L UHRF2 RFPL3	6.08e-06	223	82	8	PF00097
Domain	Znf_RING_CS	TRIM9 RNF141 TRIM62 TRIM71 DTX3L UHRF2 RNF17	7.44e-06	163	82	7	IPR017907
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	1.90e-05	2	82	2	IPR014744
Domain	ZnF_TAZ	CREBBP EP300	1.90e-05	2	82	2	SM00551
Domain	-	CREBBP EP300	1.90e-05	2	82	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	1.90e-05	2	82	2	IPR010303
Domain	-	CREBBP EP300	1.90e-05	2	82	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	1.90e-05	2	82	2	PF09030
Domain	zf-TAZ	CREBBP EP300	1.90e-05	2	82	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	1.90e-05	2	82	2	PS50134
Domain	KAT11	CREBBP EP300	1.90e-05	2	82	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	1.90e-05	2	82	2	IPR000197
Domain	KIX	CREBBP EP300	1.90e-05	2	82	2	PF02172
Domain	HAT_KAT11	CREBBP EP300	1.90e-05	2	82	2	PF08214
Domain	KIX	CREBBP EP300	1.90e-05	2	82	2	PS50952
Domain	CBP_P300_HAT	CREBBP EP300	1.90e-05	2	82	2	IPR031162
Domain	DUF902	CREBBP EP300	1.90e-05	2	82	2	PF06001
Domain	-	CREBBP EP300	1.90e-05	2	82	2	1.10.246.20
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	1.90e-05	2	82	2	IPR013178
Domain	KIX_dom	CREBBP EP300	1.90e-05	2	82	2	IPR003101
Domain	CBP_P300_HAT	CREBBP EP300	1.90e-05	2	82	2	PS51727
Domain	PHD	TRIM66 KMT2C KDM5A PHF14 UHRF2	1.96e-05	75	82	5	PF00628
Domain	ConA-like_dom	EYS MALRD1 TRIM9 TRIM62 SLIT3 ITGB4 RFPL3	5.00e-05	219	82	7	IPR013320
Domain	Growth_fac_rcpt_	CCN4 EYS ERBB4 FBN1 SLIT3 LRP1B	6.40e-05	156	82	6	IPR009030
Domain	L_dom-like	ZYG11A ERBB4 LRRC37A3 SLIT3 KDM2A SLITRK6 OGN LRRD1	9.58e-05	328	82	8	IPR032675
Domain	EGF_1	EYS FBN1 MALRD1 SLIT3 ITGB1 LRP1B ITGB4	1.30e-04	255	82	7	PS00022
Domain	EGF-like_CS	EYS FBN1 MALRD1 SLIT3 ITGB1 LRP1B ITGB4	1.50e-04	261	82	7	IPR013032
Domain	ARM-like	DOCK2 ZYG11A MTOR INSC USP9X USP9Y KPNB1	1.84e-04	270	82	7	IPR011989
Domain	Chemokine-like_FAM19A2	TAFA1 TAFA2	1.89e-04	5	82	2	IPR020350
Domain	Chemokine-like_2FAM19A2	TAFA1 TAFA2	1.89e-04	5	82	2	PD298472
Domain	TAFA	TAFA1 TAFA2	1.89e-04	5	82	2	PF12020
Domain	Zinc_finger_PHD-type_CS	TRIM66 KDM5A PHF14 KDM2A	1.91e-04	65	82	4	IPR019786
Domain	-	TRIM66 TRIM9 TRIM62 TRIM71	2.68e-04	71	82	4	4.10.45.10
Domain	Nuc_rcpt_coact	CREBBP EP300	2.82e-04	6	82	2	IPR009110
Domain	zf-B_box	TRIM66 TRIM9 TRIM62 TRIM71	2.83e-04	72	82	4	PF00643
Domain	Integrin_B_tail	ITGB1 ITGB4	3.94e-04	7	82	2	SM01242
Domain	Integrin_bsu_tail	ITGB1 ITGB4	3.94e-04	7	82	2	IPR012896
Domain	Integrin_B_tail	ITGB1 ITGB4	3.94e-04	7	82	2	PF07965
Domain	LRR_1	LRRC37A3 SLIT3 KDM2A SLITRK6 OGN LRRD1	4.05e-04	219	82	6	PF00560
Domain	ZF_BBOX	TRIM66 TRIM9 TRIM62 TRIM71	4.24e-04	80	82	4	PS50119
Domain	Znf_B-box	TRIM66 TRIM9 TRIM62 TRIM71	4.44e-04	81	82	4	IPR000315
Domain	-	ZYG11A LRRC37A3 SLIT3 KDM2A SLITRK6 OGN LRRD1	5.24e-04	321	82	7	3.80.10.10
Domain	INB	ITGB1 ITGB4	5.24e-04	8	82	2	SM00187
Domain	Integrin_bsu_VWA	ITGB1 ITGB4	5.24e-04	8	82	2	IPR002369
Domain	Integrin_beta	ITGB1 ITGB4	5.24e-04	8	82	2	PF00362
Domain	BROMODOMAIN_1	TRIM66 CREBBP EP300	5.69e-04	37	82	3	PS00633
Domain	Bromodomain	TRIM66 CREBBP EP300	6.16e-04	38	82	3	PF00439
Domain	Integrin_bsu	ITGB1 ITGB4	6.72e-04	9	82	2	IPR015812
Domain	INTEGRIN_BETA	ITGB1 ITGB4	6.72e-04	9	82	2	PS00243
Domain	PSI_integrin	ITGB1 ITGB4	6.72e-04	9	82	2	PF17205
Domain	Integin_beta_N	ITGB1 ITGB4	6.72e-04	9	82	2	IPR033760
Domain	BROMODOMAIN_2	TRIM66 CREBBP EP300	7.71e-04	41	82	3	PS50014
Domain	Bromodomain	TRIM66 CREBBP EP300	8.28e-04	42	82	3	IPR001487
Domain	BROMO	TRIM66 CREBBP EP300	8.28e-04	42	82	3	SM00297
Domain	-	TRIM66 CREBBP EP300	8.28e-04	42	82	3	1.20.920.10
Domain	NHL_repeat	TRIM71 LRP1B	8.38e-04	10	82	2	IPR001258
Domain	NHL	TRIM71 LRP1B	8.38e-04	10	82	2	PF01436
Domain	EGF_Ca-bd_CS	EYS FBN1 SLIT3 LRP1B	8.77e-04	97	82	4	IPR018097
Domain	LRR_8	LRRC37A3 SLIT3 SLITRK6 OGN LRRD1	9.38e-04	171	82	5	PF13855
Domain	EGF_CA	EYS FBN1 SLIT3 LRP1B	9.47e-04	99	82	4	PS01187
Domain	LRR_TYP	LRRC37A3 SLIT3 SLITRK6 OGN LRRD1	1.09e-03	177	82	5	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC37A3 SLIT3 SLITRK6 OGN LRRD1	1.09e-03	177	82	5	IPR003591
Domain	EGF_2	EYS FBN1 MALRD1 SLIT3 LRP1B ITGB4	1.10e-03	265	82	6	PS01186
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS FBN1 SLIT3 LRP1B	1.22e-03	106	82	4	IPR000152
Domain	Leu-rich_rpt	LRRC37A3 SLIT3 KDM2A SLITRK6 OGN LRRD1	1.23e-03	271	82	6	IPR001611
Domain	LRR	LRRC37A3 SLIT3 SLITRK6 OGN LRRD1	1.92e-03	201	82	5	PS51450
Domain	Bbox_C	TRIM66 TRIM9	1.93e-03	15	82	2	IPR003649
Domain	BBC	TRIM66 TRIM9	1.93e-03	15	82	2	SM00502
Domain	EGF_CA	EYS FBN1 SLIT3 LRP1B	2.05e-03	122	82	4	SM00179
Domain	EGF-like_Ca-bd_dom	EYS FBN1 SLIT3 LRP1B	2.17e-03	124	82	4	IPR001881
Domain	Post-SET_dom	KMT2C SETD2	2.20e-03	16	82	2	IPR003616
Domain	PostSET	KMT2C SETD2	2.20e-03	16	82	2	SM00508
Domain	POST_SET	KMT2C SETD2	2.20e-03	16	82	2	PS50868
Domain	EGF	EYS MALRD1 SLIT3 LRP1B	2.30e-03	126	82	4	PF00008
Domain	EGF_extracell	ITGB1 LRP1B ITGB4	2.33e-03	60	82	3	IPR013111
Domain	EGF_2	ITGB1 LRP1B ITGB4	2.33e-03	60	82	3	PF07974
Domain	ZF_ZZ_2	CREBBP EP300	2.78e-03	18	82	2	PS50135
Domain	CTCK_1	CCN4 SLIT3	2.78e-03	18	82	2	PS01185
Domain	ZF_ZZ_1	CREBBP EP300	2.78e-03	18	82	2	PS01357
Domain	ZZ	CREBBP EP300	2.78e-03	18	82	2	PF00569
Domain	-	ZYG11A MTOR INSC USP9X KPNB1	2.95e-03	222	82	5	1.25.10.10
Domain	Znf_ZZ	CREBBP EP300	3.10e-03	19	82	2	IPR000433
Domain	ZnF_ZZ	CREBBP EP300	3.10e-03	19	82	2	SM00291
Domain	BBOX	TRIM66 TRIM9 TRIM71	3.47e-03	69	82	3	SM00336
Domain	EGF	EYS FBN1 MALRD1 SLIT3 LRP1B	3.76e-03	235	82	5	SM00181
Domain	EGF_3	EYS FBN1 MALRD1 SLIT3 LRP1B	3.76e-03	235	82	5	PS50026
Domain	EPHD	KMT2C PHF14	4.15e-03	22	82	2	PS51805
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	CREBBP EP300 TXN	8.18e-06	10	59	3	M27945
Pathway	PID_IFNG_PATHWAY	MTOR CREBBP EP300 MAP3K1	2.26e-05	40	59	4	M161
Pathway	WP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS	SETD2 MTOR CEP290 CREBBP EP300	2.90e-05	86	59	5	M39375
Pathway	PID_TNF_PATHWAY	RFFL TNFAIP3 MAP3K1 TXN	3.96e-05	46	59	4	M128
Pathway	WP_TNFALPHA_SIGNALING	RFFL TNFAIP3 CREBBP MAP3K1 TXN	4.02e-05	92	59	5	M39662
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	CREBBP EP300 TXN	6.43e-05	19	59	3	M46442
Pathway	PID_NFAT_3PATHWAY	CREBBP EP300 MAP3K1 KPNB1	6.95e-05	53	59	4	M113
Pathway	PID_MYC_REPRESS_PATHWAY	ALDH9A1 ITGB1 ITGB4 EP300	1.37e-04	63	59	4	M254
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	KMT2C SETD2 CREBBP EP300	1.55e-04	65	59	4	M39682
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	1.71e-04	5	59	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	1.71e-04	5	59	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	1.71e-04	5	59	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	1.71e-04	5	59	2	M27228
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	RNF7 UBE3D TRIM9 RBBP6 TRIM71 ASB4 DTX3L	2.39e-04	299	59	7	MM15711
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	2.56e-04	6	59	2	M22062
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	RNF7 UBE3D TRIM9 RBBP6 TRIM71 ASB4 DTX3L	2.86e-04	308	59	7	M1070
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	3.57e-04	7	59	2	MM1573
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	TNFAIP3 CREBBP EP300 MAP3K1	3.79e-04	82	59	4	M1002
Pathway	WP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA	SETD2 CREBBP EP300	3.80e-04	34	59	3	M39771
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	4.74e-04	8	59	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	4.74e-04	8	59	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	4.74e-04	8	59	2	M48024
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	4.74e-04	8	59	2	M46443
Pathway	PID_RAC1_REG_PATHWAY	DOCK2 KALRN PREX2	5.29e-04	38	59	3	M241
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	MTOR CREBBP EP300	5.29e-04	38	59	3	M27255
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	RNF7 UBE3D TRIM9 RBBP6 TRIM71 ASB4 DTX3L	5.46e-04	343	59	7	MM15712
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	6.08e-04	9	59	2	M47451
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	FBN1 USP9X ITGB1 EP300	6.37e-04	94	59	4	M1041
Pathway	PID_TCPTP_PATHWAY	ITGB1 CREBBP KPNB1	7.12e-04	42	59	3	M91
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	UHRF2 CREBBP EP300	8.16e-04	44	59	3	M27295
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	9.24e-04	11	59	2	MM1521
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300	9.24e-04	11	59	2	M48021
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	9.24e-04	11	59	2	M26924
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	KMT2C SETD2 KDM5A KDM2A CREBBP EP300	9.34e-04	272	59	6	M29619
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	DTX3L CREBBP EP300	9.91e-04	47	59	3	M7946
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	RNF7 UBE3D TRIM9 RBBP6 TRIM71 ASB4 DTX3L	1.01e-03	381	59	7	M1066
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	1.11e-03	12	59	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	1.11e-03	12	59	2	M27765
Pathway	PID_TAP63_PATHWAY	OGG1 ITGB4 EP300	1.48e-03	54	59	3	M256
Pathway	BIOCARTA_CD40_PATHWAY	TNFAIP3 MAP3K1	1.52e-03	14	59	2	MM1362
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP EP300	1.52e-03	14	59	2	M27808
Pathway	REACTOME_SYNDECAN_INTERACTIONS	ITGB1 ITGB4	1.52e-03	14	59	2	MM14923
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	1.75e-03	15	59	2	MM1339
Pathway	BIOCARTA_CD40_PATHWAY	TNFAIP3 MAP3K1	1.75e-03	15	59	2	M16697
Pathway	BIOCARTA_BCELLSURVIVAL_PATHWAY	MTOR ITGB1	1.75e-03	15	59	2	M4835
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	1.75e-03	15	59	2	M10183
Pathway	REACTOME_LAMININ_INTERACTIONS	ITGB1 ITGB4	1.75e-03	15	59	2	MM14922
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	1.75e-03	15	59	2	MM1439
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP EP300	1.75e-03	15	59	2	M953
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	FBN1 CREBBP EP300	1.92e-03	59	59	3	M39886
Pathway	PID_SMAD2_3PATHWAY	MAP3K1 KPNB1	1.99e-03	16	59	2	M228
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP EP300	1.99e-03	16	59	2	M27121
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.99e-03	16	59	2	M1296
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.99e-03	16	59	2	MM1420
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	1.99e-03	16	59	2	M8516
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES	CREBBP EP300	1.99e-03	16	59	2	M27940
Pathway	WP_EBOLA_VIRUS_INFECTION_IN_HOST	VPS39 ITGB1 CREBBP EP300	2.06e-03	129	59	4	M39693
Pathway	BIOCARTA_BCELLSURVIVAL_PATHWAY	MTOR ITGB1	2.25e-03	17	59	2	MM1353
Pathway	BIOCARTA_TNFR2_PATHWAY	TNFAIP3 MAP3K1	2.25e-03	17	59	2	M10082
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	2.25e-03	17	59	2	MM1509
Pathway	BIOCARTA_TNFR2_PATHWAY	TNFAIP3 MAP3K1	2.25e-03	17	59	2	MM1517
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	CREBBP EP300	2.25e-03	17	59	2	M48025
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK2 DSG1 KALRN RBBP6 USP9X ITGB1 PREX2	2.28e-03	439	59	7	MM15595
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2C SETD2 KDM5A KDM2A CREBBP EP300	5.44e-09	57	84	6	18022353
Pubmed	Mutations in CREBBP and EP300 genes affect DNA repair of oxidative damage in Rubinstein-Taybi syndrome cells.	OGG1 CREBBP EP300	1.36e-08	3	84	3	31504229
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	RNF7 CEP290 EIF4G2 KDM2A CREBBP EP300	1.76e-08	69	84	6	32238831
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C CREBBP EP300	5.43e-08	4	84	3	28398509
Pubmed	A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer.	CREBBP EP300 KPNB1	2.70e-07	6	84	3	32494626
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TRIM66 FBN1 KALRN KDM5A TRIM9 VPS39 USP9X CEP290 EIF4G2 ZNFX1 USP9Y LRP1B CREBBP EP300 KPNB1	4.08e-07	1285	84	15	35914814
Pubmed	Cooperation between Myc and YY1 provides novel silencing transcriptional targets of alpha3beta1-integrin in tumour cells.	ITGB1 ITGB4 CREBBP	7.54e-07	8	84	3	16878156
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KMT2C SETD2 RNF168 LUC7L3 KDM5A RBBP6 CEP290 EIF4G2 PHF14 KDM2A CENPS EP300 NPM3 KPNB1	2.53e-06	1294	84	14	30804502
Pubmed	A human MAP kinase interactome.	KMT2C RBBP6 CEP290 MYO18A KDM2A TNFAIP3 ITGB4 CREBBP EP300	2.75e-06	486	84	9	20936779
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	FCF1 RNF168 LUC7L3 DSG1 RBBP6 MAT1A MYO18A UPF1 TNFAIP3 ATP1A1 KPNB1 TXN	2.96e-06	949	84	12	36574265
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ZBTB49 KMT2C SETD2 KDM5A UBE3D VPS39 USP9X PHF14 KDM2A UPF1 ITGB1 NDUFS1 EP300 PREX2	3.38e-06	1327	84	14	32694731
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	CCN4 KMT2C ERBB4 EFCAB6 SLIT3 TNFAIP3 TAFA2	3.78e-06	265	84	7	19240061
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	5.76e-06	2	84	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	5.76e-06	2	84	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	5.76e-06	2	84	2	19729597
Pubmed	Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes.	MTOR TXN	5.76e-06	2	84	2	28939765
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	5.76e-06	2	84	2	39287984
Pubmed	Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs.	FBN1 TNFAIP3	5.76e-06	2	84	2	36289219
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	5.76e-06	2	84	2	20717166
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	5.76e-06	2	84	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	5.76e-06	2	84	2	11559821
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	5.76e-06	2	84	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	5.76e-06	2	84	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	5.76e-06	2	84	2	24522976
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	5.76e-06	2	84	2	21847097
Pubmed	p300 Acetylates JHDM1A to inhibit osteosarcoma carcinogenesis.	KDM2A EP300	5.76e-06	2	84	2	31307234
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9X USP9Y	5.76e-06	2	84	2	12895410
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	5.76e-06	2	84	2	34813504
Pubmed	A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy.	ITGB1 ITGB4	5.76e-06	2	84	2	29700202
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	5.76e-06	2	84	2	20301699
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	5.76e-06	2	84	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	5.76e-06	2	84	2	37816914
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	5.76e-06	2	84	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	5.76e-06	2	84	2	10918613
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	5.76e-06	2	84	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	5.76e-06	2	84	2	31898871
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	5.76e-06	2	84	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	5.76e-06	2	84	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	5.76e-06	2	84	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	5.76e-06	2	84	2	32690000
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	5.76e-06	2	84	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	5.76e-06	2	84	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	5.76e-06	2	84	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	5.76e-06	2	84	2	24089570
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9X USP9Y	5.76e-06	2	84	2	8922996
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	5.76e-06	2	84	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	5.76e-06	2	84	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	5.76e-06	2	84	2	22303793
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	5.76e-06	2	84	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	5.76e-06	2	84	2	34019788
Pubmed	Asprosin promotes β-cell apoptosis by inhibiting the autophagy of β-cell via AMPK-mTOR pathway.	FBN1 MTOR	5.76e-06	2	84	2	32557691
Pubmed	Spatiotemporally-regulated interaction between β1 integrin and ErbB4 that is involved in fibronectin-dependent cell migration.	ERBB4 ITGB1	5.76e-06	2	84	2	21217148
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	5.76e-06	2	84	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	5.76e-06	2	84	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	5.76e-06	2	84	2	24551300
Pubmed	Immunohistochemical localization of beta1 and beta4 integrins in mouse endometrium during implantation and early pregnancy.	ITGB1 ITGB4	5.76e-06	2	84	2	16268053
Pubmed	Integrators of epidermal growth and differentiation: distinct functions for beta 1 and beta 4 integrins.	ITGB1 ITGB4	5.76e-06	2	84	2	9388785
Pubmed	Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition.	MTOR USP9X	5.76e-06	2	84	2	37260183
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	5.76e-06	2	84	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	5.76e-06	2	84	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	5.76e-06	2	84	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	5.76e-06	2	84	2	30135524
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	5.76e-06	2	84	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	5.76e-06	2	84	2	29217654
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	5.76e-06	2	84	2	10049825
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	5.76e-06	2	84	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	5.76e-06	2	84	2	29170789
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	5.76e-06	2	84	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	5.76e-06	2	84	2	12646247
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9X USP9Y	5.76e-06	2	84	2	12925892
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	5.76e-06	2	84	2	11867645
Pubmed	UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.	MTOR UPF1	5.76e-06	2	84	2	34520393
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	5.76e-06	2	84	2	11963968
Pubmed	Expanding the molecular signature of ossifying fibromyxoid tumors with two novel gene fusions: CREBBP-BCORL1 and KDM2A-WWTR1.	KDM2A CREBBP	5.76e-06	2	84	2	27537276
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	5.76e-06	2	84	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	5.76e-06	2	84	2	12696060
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	5.76e-06	2	84	2	36109165
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	5.76e-06	2	84	2	12242694
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	5.76e-06	2	84	2	31182547
Pubmed	Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.	CREBBP EP300	5.76e-06	2	84	2	30635043
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	5.76e-06	2	84	2	27648933
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	5.76e-06	2	84	2	10610021
Pubmed	Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.	CREBBP EP300	5.76e-06	2	84	2	37314181
Pubmed	Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.	CREBBP EP300	5.76e-06	2	84	2	12397173
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	5.76e-06	2	84	2	15641773
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.	CREBBP EP300	5.76e-06	2	84	2	9733868
Pubmed	Rubinstein-Taybi syndrome in Chinese population with four novel mutations.	CREBBP EP300	5.76e-06	2	84	2	33063428
Pubmed	EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.	CREBBP EP300	5.76e-06	2	84	2	34506759
Pubmed	Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.	CREBBP EP300	5.76e-06	2	84	2	22177454
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	RNF7 TRIM9 RNF141 DTX3L UHRF2	5.82e-06	105	84	5	22493164
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SETD2 LUC7L3 DSG1 RBBP6 USP9X ATP1A1 CREBBP EP300 SEC23B KPNB1	6.95e-06	695	84	10	23602568
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2C SETD2 RBBP6 USP9X KDM2A UPF1 CREBBP EP300 KPNB1	7.34e-06	549	84	9	38280479
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	ERBB4 DDAH1 KALRN MTOR UPF1 SEC23B KPNB1	9.27e-06	304	84	7	32235678
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	RNF168 RFFL UHRF2 RNF17 MAP3K1	1.03e-05	118	84	5	19690564
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	MTOR USP9X EP300	1.08e-05	18	84	3	33323119
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SETD2 LUC7L3 KALRN KDM5A RBBP6 MYO18A TRIM71 UPF1 USP9Y NDUFS1 SEC23B KPNB1	1.11e-05	1082	84	12	38697112
Pubmed	Functional proteomics mapping of a human signaling pathway.	RNF168 RBBP6 TRIM62 EIF4G2 KDM2A TNFAIP3 UHRF2 CREBBP KPNB1	1.32e-05	591	84	9	15231748
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	DYM FBN1 TRIM9 VPS39 MTOR CEP290 MYO18A UPF1 ALDH9A1 ITGB1	1.41e-05	754	84	10	33060197
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	EYS USP9X KDM2A OGG1 CREBBP EP300 KPNB1	1.64e-05	332	84	7	37433992
Pubmed	The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.	CREBBP EP300	1.73e-05	3	84	2	18070920
Interaction	UBE2D1 interactions	RNF7 RNF168 USP9X TRIM62 TRIM71 RFFL ASB4 DTX3L TNFAIP3 UHRF2 CREBBP EP300 MAP3K1	2.21e-10	294	83	13	int:UBE2D1
Interaction	CUL4A interactions	RNF7 ERBB4 DDAH1 KALRN MTOR USP9X SHCBP1 ASB4 PRR14L UPF1 ATP1A1 EP300 SEC23B MAP3K1 KPNB1	1.86e-06	854	83	15	int:CUL4A
Interaction	TRIM8 interactions	RNF7 RNF168 TRIM9 RNF141 TNFAIP3 UHRF2	3.56e-06	100	83	6	int:TRIM8
Interaction	UBE2D2 interactions	RNF7 RNF168 USP9X TRIM62 RFFL DTX3L UHRF2 MAP3K1 TXN	6.39e-06	318	83	9	int:UBE2D2
Interaction	H3-4 interactions	ANO4 KMT2C SETD2 MMS22L KDM5A CEP290 KDM2A CREBBP EP300 KPNB1	1.52e-05	448	83	10	int:H3-4
Interaction	EED interactions	FCF1 LUC7L3 KDM5A RBBP6 VPS39 USP9X CEP290 MYO18A TRIM71 KDM2A UPF1 ATP1A1 UHRF2 NDUFS1 SEC23B NPM3 KPNB1 TXN	1.91e-05	1445	83	18	int:EED
Interaction	UBE2D3 interactions	RNF7 RNF168 TRIM62 RFFL DTX3L TNFAIP3 UHRF2 MAP3K1	2.17e-05	283	83	8	int:UBE2D3
Interaction	PROX1 interactions	TRIM66 INSC CREBBP EP300	2.41e-05	41	83	4	int:PROX1
Interaction	PSD2 interactions	ZBTB49 SETD2 EP300	2.96e-05	15	83	3	int:PSD2
GeneFamily	Ring finger proteins	RNF7 RNF168 TRIM9 RNF141 TRIM62 TRIM71 RFFL DTX3L UHRF2 RNF17	5.07e-09	275	52	10	58
GeneFamily	PHD finger proteins	TRIM66 KMT2C KDM5A PHF14 KDM2A UHRF2	2.18e-07	90	52	6	88
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM66 TRIM9 TRIM62 TRIM71 TRIM51G	7.70e-06	95	52	5	59
GeneFamily	CD molecules\|Integrin beta subunits	ITGB1 ITGB4	2.88e-04	9	52	2	1159
GeneFamily	UPF1 like RNA helicases	ZNFX1 UPF1	4.39e-04	11	52	2	1169
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.07e-03	17	52	2	486
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.21e-03	18	52	2	91
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5A KDM2A	2.15e-03	24	52	2	485
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C SETD2	4.29e-03	34	52	2	487
GeneFamily	Tudor domain containing	UHRF2 RNF17	5.07e-03	37	52	2	780
GeneFamily	Fibronectin type III domain containing	KALRN TRIM9 ITGB4	1.09e-02	160	52	3	555
GeneFamily	Ubiquitin specific peptidases	USP9X USP9Y	1.13e-02	56	52	2	366
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KALRN PREX2	1.55e-02	66	52	2	722
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KMT2C SETD2 USP9X KDM2A PRR14L CREBBP EP300	1.71e-06	180	83	7	M8239
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	KMT2C SETD2 RBBP6 USP9X ZNFX1 DTX3L TNFAIP3	5.71e-08	183	84	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF141 USP9X EIF4G2 ATP1A1 ITGB1 ITGB4 MAP3K1	9.78e-08	198	84	7	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPYD KALRN SLIT3 SLITRK6 OGN PREX2	1.83e-06	194	84	6	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 DDAH1 FBN1 KALRN SLIT3 PREX2	2.00e-06	197	84	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 DDAH1 FBN1 KALRN SLIT3 PREX2	2.00e-06	197	84	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 DDAH1 FBN1 KALRN SLIT3 PREX2	2.00e-06	197	84	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDAH1 RNF168 MTOR TRIM62 CENPS	1.35e-05	161	84	5	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 DDAH1 FBN1 ASB4 TAFA2	1.66e-05	168	84	5	f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANO4 ERBB4 DDAH1 MAP3K1 TAFA2	1.81e-05	171	84	5	f9ae7964a3740f559431125c17c660549798cccc
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANO4 ERBB4 DDAH1 MAP3K1 TAFA2	1.97e-05	174	84	5	a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANO4 FBN1 SLIT3 OGN LRP1B	2.08e-05	176	84	5	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANO4 FBN1 SLIT3 OGN LRP1B	2.08e-05	176	84	5	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	KALRN MYO18A LRP1B ITGB4 PREX2	2.14e-05	177	84	5	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CCN4 KALRN TRIM9 STARD9 SLIT3	2.26e-05	179	84	5	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A USP9X EIF4G2 ATP1A1 ITGB1	2.44e-05	182	84	5	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANO4 FBN1 STARD9 SLITRK6 OGN	2.64e-05	185	84	5	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SLIT3 TAFA1 OGN LRP1B TAFA2	2.71e-05	186	84	5	8915436d09775f2828a7678af203b1082b36e21c
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	VPS13D RBBP6 CREBBP EP300 MAP3K1	2.71e-05	186	84	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANO4 FBN1 STARD9 SLITRK6 OGN	2.78e-05	187	84	5	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 KALRN TRIM9 STARD9 SLIT3	2.78e-05	187	84	5	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 KALRN TRIM9 STARD9 SLIT3	2.78e-05	187	84	5	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 KALRN TRIM9 STARD9 SLIT3	2.85e-05	188	84	5	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	MMS22L ERBB4 ABCA5 ATP1A1 LRP1B	2.85e-05	188	84	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 MALRD1 ABCA5 ATP1A1 LRP1B	2.93e-05	189	84	5	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DPYD SLITRK6 OGN LRP1B PREX2	3.00e-05	190	84	5	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATP8B4 INSC STARD9 SLIT3 TNFAIP3	3.08e-05	191	84	5	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATP8B4 INSC STARD9 SLIT3 TNFAIP3	3.08e-05	191	84	5	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPYD KALRN OGN LRP1B PREX2	3.08e-05	191	84	5	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATP8B4 INSC STARD9 SLIT3 TNFAIP3	3.08e-05	191	84	5	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN STARD9 SLIT3	3.08e-05	191	84	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	Control-Lymphoid_T/NK-NK_CD56bright\|Control / Disease group, lineage and cell class	ATP8B4 INSC STARD9 SLIT3 TNFAIP3	3.08e-05	191	84	5	e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATP8B4 INSC STARD9 SLIT3 TNFAIP3	3.08e-05	191	84	5	c023ca893ceae19b54967096f6e2588dc39fa268
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPYD DDAH1 KALRN SLIT3 TAFA1	3.16e-05	192	84	5	5c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN SLIT3 PREX2	3.23e-05	193	84	5	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN SLIT3 PREX2	3.23e-05	193	84	5	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	Fibroblasts-CD34+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	INSC SLIT3 SLITRK6 OGN PREX2	3.40e-05	195	84	5	c6b5249ac8714b1b701cde31d00ab53f28355c36
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN SLIT3 PREX2	3.48e-05	196	84	5	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN SLIT3 PREX2	3.48e-05	196	84	5	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	(2)_NK/T-(231)_CD4+/CD45RO+_Memory_T_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	TNFAIP3 ITGB1 MAP3K1 NPM3 TXN	3.48e-05	196	84	5	5267acead12207f238d9afa3eef8ac1168b47082
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 FBN1 KALRN SLIT3 PREX2	3.57e-05	197	84	5	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INSC TAFA1 PHF14 SLITRK6 ITGB1	3.57e-05	197	84	5	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	LUC7L3 KDM5A RBBP6 CEP290 PHF14	3.57e-05	197	84	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X EIF4G2 ATP1A1 NDUFS1 MAP3K1	3.65e-05	198	84	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN4 INSC SLITRK6 ITGB1 PREX2	3.65e-05	198	84	5	d83707b69fb64721ac3cff90ba58cdd999d6b386
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TRIM9 INSC SLITRK6 OGN NPM3	3.65e-05	198	84	5	d9d3520705a1142083782f077a0c5604d3ea99af
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DDAH1 FBN1 KALRN SLIT3 PREX2	3.65e-05	198	84	5	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT3 TAFA1 PHF14 SLITRK6 ITGB1	3.65e-05	198	84	5	75d104eead681f6bf47c4dd24913cc768c9a1717
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYD ERBB4 TRIM9 INSC SLITRK6	3.65e-05	198	84	5	c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X EIF4G2 ATP1A1 NDUFS1 MAP3K1	3.65e-05	198	84	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X EIF4G2 ATP1A1 ITGB1 MAP3K1	3.74e-05	199	84	5	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CCN4 FBN1 TRIM9 SLIT3 OGN	3.74e-05	199	84	5	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	KMT2C DPYD ERBB4 DYM LRRC37A3	3.74e-05	199	84	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 SLIT3 SLITRK6 OGN PREX2	3.74e-05	199	84	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYD ERBB4 TRIM9 INSC SLITRK6	3.74e-05	199	84	5	8d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	CCN4 FBN1 SLIT3 SLITRK6 OGN	3.83e-05	200	84	5	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO4 RNF141 EIF4G2 ATP1A1 ITGB1	3.83e-05	200	84	5	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C SETD2 KDM2A DTX3L TNFAIP3	3.83e-05	200	84	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	ANO4 FBN1 INSC SLITRK6 ITGB1	3.83e-05	200	84	5	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KMT2C SETD2 RBBP6 KDM2A TNFAIP3	3.83e-05	200	84	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	CCN4 FBN1 SLIT3 SLITRK6 OGN	3.83e-05	200	84	5	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	CCN4 FBN1 SLIT3 SLITRK6 OGN	3.83e-05	200	84	5	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	facs-Aorta-Heart-24m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB49 TESMIN VPS39 SHCBP1	7.38e-05	118	84	4	171afacd54b2e447f9f8c4511e93ff4504cd47cc
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	RNF7 INSC RNF141 ITGB4	1.04e-04	129	84	4	b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	TRIM9 TRIM62 USP9Y ITGB4	1.11e-04	131	84	4	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 MMS22L MALRD1 TAFA1	1.21e-04	134	84	4	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 CCN4 SLIT3 RNF17	1.77e-04	148	84	4	f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 CCN4 SLIT3 RNF17	1.77e-04	148	84	4	4b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 CCN4 SLIT3 RNF17	1.77e-04	148	84	4	55826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	CCN4 FBN1 OGN MAP3K1	1.81e-04	149	84	4	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CCN4 DDAH1 STARD9 TAFA1	1.91e-04	151	84	4	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	facs-Skin-nan-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZYG11A USP9Y RNF17 TXN	2.11e-04	155	84	4	fa2776d258e0420b2895de1008e292ad7725dac0
ToppCell	Adult-Immune-mast_cell-D122\|Adult / Lineage, Cell type, age group and donor	ATP8B4 TESMIN TRIM9 LRP1B	2.11e-04	155	84	4	7c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANO4 ERBB4 MAP3K1 TAFA2	2.16e-04	156	84	4	896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB4 MALRD1 ASB4 ATP1A1	2.33e-04	159	84	4	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 DDAH1 ASB4 TAFA2	2.44e-04	161	84	4	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB4 ABCA5 USP9Y LRP1B	2.50e-04	162	84	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHCBP1 TAFA1 TRIM71 LRP1B	2.56e-04	163	84	4	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHCBP1 TAFA1 TRIM71 LRP1B	2.56e-04	163	84	4	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM9 SLIT3 LRRD1 PREX2	2.56e-04	163	84	4	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KALRN TAFA1 ATP1A1 TAFA2	2.56e-04	163	84	4	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KALRN TAFA1 ATP1A1 TAFA2	2.56e-04	163	84	4	431221a41d396b09170476179590eaf8a55266d8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM9 SLIT3 LRRD1 PREX2	2.56e-04	163	84	4	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	EFCAB6 TAFA1 TNFAIP3 ITGB1	2.62e-04	164	84	4	8f3255d7f67890389a768453492243ea982eb38a
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 SLIT3 OGN LRRD1	2.68e-04	165	84	4	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	INSC SLITRK6 ITGB4 RFPL3	2.68e-04	165	84	4	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 SLIT3 OGN LRRD1	2.80e-04	167	84	4	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAT1A TRIM71 ASB4 RNF17	2.87e-04	168	84	4	e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAT1A TRIM71 ASB4 RNF17	2.87e-04	168	84	4	16b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSC TAFA1 TRIM71 LRRD1	2.93e-04	169	84	4	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSC TAFA1 TRIM71 LRRD1	2.93e-04	169	84	4	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 FBN1 SLIT3 SLITRK6	2.93e-04	169	84	4	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSC TAFA1 TRIM71 LRRD1	2.93e-04	169	84	4	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	INSC SLITRK6 ITGB4 RFPL3	2.93e-04	169	84	4	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 PRR14L OGN PREX2	3.00e-04	170	84	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 KALRN STARD9 ITGB4	3.00e-04	170	84	4	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 KALRN STARD9 ITGB4	3.00e-04	170	84	4	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 KALRN STARD9 ITGB4	3.00e-04	170	84	4	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	368C-Lymphocytic-ILC\|368C / Donor, Lineage, Cell class and subclass (all cells)	TESMIN UBE3D TAFA1 TAFA2	3.07e-04	171	84	4	3b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell	368C-Lymphocytic-ILC-ILC-2\|368C / Donor, Lineage, Cell class and subclass (all cells)	TESMIN UBE3D TAFA1 TAFA2	3.07e-04	171	84	4	fd01076574dcc82bfd4a1538812500543b16794f
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZBTB49 MALRD1 LRRC37A3 SLITRK6	3.07e-04	171	84	4	04346d4eb726875e3537e215ea081a0318ca4ddd
Disease	stomach carcinoma (is_marker_for)	KMT2C ERBB4 KDM5A TNFAIP3	6.22e-07	24	84	4	DOID:5517 (is_marker_for)
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	8.01e-06	2	84	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	8.01e-06	2	84	2	cv:C4551859
Disease	Menke-Hennekam syndrome	CREBBP EP300	8.01e-06	2	84	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	8.01e-06	2	84	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	8.01e-06	2	84	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	8.01e-06	2	84	2	C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	8.01e-06	2	84	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	8.01e-06	2	84	2	C0035934
Disease	Adenoid Cystic Carcinoma	KMT2C SETD2 ITGB4 CREBBP EP300	1.01e-05	100	84	5	C0010606
Disease	lung adenocarcinoma (is_implicated_in)	KMT2C SETD2 ERBB4 LRP1B	1.17e-05	49	84	4	DOID:3910 (is_implicated_in)
Disease	colorectal cancer (is_implicated_in)	SETD2 ERBB4 TNFAIP3 LRP1B EP300	2.54e-05	121	84	5	DOID:9256 (is_implicated_in)
Disease	severe acute respiratory syndrome, COVID-19	EYS MALRD1 USP9X TAFA1 PHF14 CENPS LRP1B PREX2	4.15e-05	447	84	8	EFO_0000694, MONDO_0100096
Disease	body weight	TRIM66 DPYD SETD2 MMS22L EYS ERBB4 UBE3D MTOR SLIT3 KDM2A LRP1B KPNB1 TAFA2	5.55e-05	1261	84	13	EFO_0004338
Disease	Klatskin's tumor (is_implicated_in)	KMT2C PREX2	7.96e-05	5	84	2	DOID:4927 (is_implicated_in)
Disease	Breast Carcinoma	DPYD SETD2 ERBB4 VPS39 MTOR EP300 MAP3K1 TXN	1.50e-04	538	84	8	C0678222
Disease	Carcinoma, Transitional Cell	KMT2C CREBBP EP300	2.19e-04	41	84	3	C0007138
Disease	head and neck squamous cell carcinoma (is_marker_for)	ERBB4 OGG1	2.22e-04	8	84	2	DOID:5520 (is_marker_for)
Disease	alcohol use disorder (implicated_via_orthology)	ERBB4 KDM5A ATP1A1 CREBBP EP300	2.42e-04	195	84	5	DOID:1574 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KMT2C ERBB4 MAP3K1	2.90e-04	45	84	3	DOID:3748 (is_implicated_in)
Disease	coronary artery calcification	ZBTB49 EYS DSG1 TRIM9 STARD9 EIF4G2 LRP1B	3.02e-04	450	84	7	EFO_0004723
Disease	Neoplasm Metastasis	CCN4 DPYD ITGB1 OGN TXN	3.96e-04	217	84	5	C0027627
Disease	pneumococcal bacteremia	DOCK2 CCN4	4.33e-04	11	84	2	EFO_1001925
Disease	body surface area	TRIM66 DDAH1 DYM FBN1 UBE3D MTOR SLIT3 KDM2A	4.96e-04	643	84	8	EFO_0022196
Disease	Sarcomatoid Renal Cell Carcinoma	SETD2 MTOR OGG1 LRP1B	4.98e-04	128	84	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	SETD2 MTOR OGG1 LRP1B	4.98e-04	128	84	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	SETD2 MTOR OGG1 LRP1B	4.98e-04	128	84	4	C1266044
Disease	Papillary Renal Cell Carcinoma	SETD2 MTOR OGG1 LRP1B	4.98e-04	128	84	4	C1306837
Disease	Renal Cell Carcinoma	SETD2 MTOR OGG1 LRP1B	4.98e-04	128	84	4	C0007134
Disease	mood instability measurement	MMS22L EYS LRP1B EP300	4.98e-04	128	84	4	EFO_0008475
Disease	irritable bowel syndrome	FCF1 ERBB4 ASB4 EP300	5.44e-04	131	84	4	EFO_0000555
Disease	homostachydrine measurement	EYS ERBB4	6.12e-04	13	84	2	EFO_0021164
Disease	lung non-small cell carcinoma (is_implicated_in)	KMT2C KDM2A LRP1B MAP3K1	6.80e-04	139	84	4	DOID:3908 (is_implicated_in)
Disease	Bladder Neoplasm	KMT2C MTOR CREBBP EP300	6.98e-04	140	84	4	C0005695
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	SETD2 CREBBP EP300	7.11e-04	61	84	3	C1961102
Disease	Malignant neoplasm of urinary bladder	KMT2C MTOR CREBBP EP300	7.17e-04	141	84	4	C0005684
Disease	Mammary Carcinoma, Human	DPYD SETD2 VPS39 MTOR EP300 MAP3K1 TXN	7.54e-04	525	84	7	C4704874
Disease	Mammary Neoplasms, Human	DPYD SETD2 VPS39 MTOR EP300 MAP3K1 TXN	7.54e-04	525	84	7	C1257931
Disease	Mammary Neoplasms	DPYD SETD2 VPS39 MTOR EP300 MAP3K1 TXN	7.71e-04	527	84	7	C1458155
Disease	serum dimethylarginine measurement	ERBB4 DDAH1 LRP1B	7.81e-04	63	84	3	EFO_0005418
Disease	acute graft vs. host disease, donor genotype effect measurement	EYS KALRN	8.21e-04	15	84	2	EFO_0004599, EFO_0007892
Disease	Lymphoma, Follicular, Grade 2	TNFAIP3 CREBBP	8.21e-04	15	84	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	TNFAIP3 CREBBP	8.21e-04	15	84	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	TNFAIP3 CREBBP	8.21e-04	15	84	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	TNFAIP3 CREBBP	8.21e-04	15	84	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	TNFAIP3 CREBBP	8.21e-04	15	84	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	TNFAIP3 CREBBP	8.21e-04	15	84	2	C0079758
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	SETD2 MTOR OGG1 LRP1B	8.59e-04	148	84	4	C0279702
Disease	Colorectal Carcinoma	KMT2C DPYD KALRN ABCA5 KDM2A UHRF2 EP300 PREX2	8.77e-04	702	84	8	C0009402
Disease	Malignant neoplasm of breast	DPYD SETD2 ERBB4 KALRN VPS39 MTOR DTX3L EP300 MAP3K1 TXN	9.42e-04	1074	84	10	C0006142
Disease	prostate cancer (is_marker_for)	KMT2C ERBB4 KDM5A EP300	1.04e-03	156	84	4	DOID:10283 (is_marker_for)
Disease	Astrocytosis	ITGB1 ITGB4	1.06e-03	17	84	2	C3887640
Disease	Gliosis	ITGB1 ITGB4	1.06e-03	17	84	2	C0017639
Disease	stomach cancer (is_implicated_in)	KMT2C LRP1B MAP3K1	1.15e-03	72	84	3	DOID:10534 (is_implicated_in)
Disease	migraine disorder, endometriosis	EYS ERBB4 LRP1B	1.20e-03	73	84	3	EFO_0001065, MONDO_0005277
Disease	lung non-small cell carcinoma (is_marker_for)	KDM5A KDM2A ITGB1 PREX2	1.40e-03	169	84	4	DOID:3908 (is_marker_for)
Disease	glomerulonephritis (biomarker_via_orthology)	FBN1 ITGB1	1.47e-03	20	84	2	DOID:2921 (biomarker_via_orthology)
Disease	Lymphoma, Follicular	TNFAIP3 CREBBP	1.47e-03	20	84	2	C0024301
Disease	Leukemia, Myelocytic, Acute	KMT2C SETD2 CREBBP EP300	1.53e-03	173	84	4	C0023467
Disease	leptin measurement	DOCK2 SLIT3 LRP1B	1.62e-03	81	84	3	EFO_0005000
Disease	hepatocellular carcinoma (is_marker_for)	MTOR TNFAIP3 LRP1B PREX2 MAP3K1	1.71e-03	301	84	5	DOID:684 (is_marker_for)
Disease	thyroxine measurement	ERBB4 STARD9 TRIM71	1.74e-03	83	84	3	EFO_0005130
Disease	cholangiocarcinoma (is_implicated_in)	OGG1 PREX2	1.78e-03	22	84	2	DOID:4947 (is_implicated_in)
Disease	household income	DPYD MMS22L ERBB4 KALRN LRP1B	1.79e-03	304	84	5	EFO_0009695
Disease	information processing speed	DSG1 INSC LRP1B	1.86e-03	85	84	3	EFO_0004363
Disease	unipolar depression, neuroticism measurement	ANO4 EYS	2.12e-03	24	84	2	EFO_0003761, EFO_0007660
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SLIT3 EP300	2.12e-03	24	84	2	DOID:3827 (biomarker_via_orthology)
Disease	Brain Diseases	MAT1A OGG1	2.30e-03	25	84	2	C0006111
Disease	visuospatial function measurement	DDAH1 LRRD1	2.49e-03	26	84	2	EFO_0803533
Disease	visceral adipose tissue measurement	TRIM66 DPYD MMS22L ERBB4 MTOR SLITRK6	2.53e-03	481	84	6	EFO_0004765
Disease	Squamous cell carcinoma of esophagus	KMT2C CREBBP EP300	2.55e-03	95	84	3	C0279626
Disease	indole-3-propionate measurement	SLIT3 EIF4G2	2.68e-03	27	84	2	EFO_0010501
Disease	Encephalopathies	MAT1A OGG1	2.68e-03	27	84	2	C0085584
Disease	Sezary Syndrome	KMT2C CREBBP	2.68e-03	27	84	2	C0036920

Protein segments in the cluster

Peptide	Gene	Start	Entry
ERLKVKELMGCQCCE	ABCA5	1271	Q8WWZ7
KELMGCQCCEEKPSI	ABCA5	1276	Q8WWZ7
CQCCEEKPSIMVSNL	ABCA5	1281	Q8WWZ7
EENGIKMCKPCTDIC	ERBB4	316	Q15303
ICVECDPQCEKMEDG	ERBB4	551	Q15303
ECTECGRKMHQICVL	EP300	1246	Q09472
CVLTNCRDDMTCVKE	ALDH9A1	376	P49189
TVGCLCEEVALDKEM	CENPS	26	Q8N2Z9
EMANVDCVKILCDRG	ASB4	116	Q9Y574
VDCKECGRKMHQICV	CREBBP	1281	Q92793
LCLSVCPIVDCIKMV	DPYD	991	Q12882
LELACMCKTVICCRV	ATP8B4	776	Q8TF62
VSLITDGCECCKMCA	CCN4	66	O95388
KEVCQATDIIMCPVC	ANO4	386	Q32M45
ECDTCAICRVQVMDA	RNF7	46	Q9UBF6
EMCQTCLGVCAEHKE	ITGB1	631	P05556
EKLIVPSHMACCLCQ	LRRC37A3	1016	O60309
NIPEKISCCAMLECL	LRRD1	386	A4D1F6
LGATIKCCEEKCTQM	KMT2C	291	Q8NEZ4
MDCVTECKEDQFRCK	LRP1B	3626	Q9NZR2
ETDFQICLLCKEMCG	TRIM71	6	Q2Q1W2
DCIKISNDVMCICSP	EYS	346	Q5T1H1
LTMLCLTEGAKDECN	NPM3	66	O75607
ESLMSDQCPCLCIKE	MMS22L	281	Q6ZRQ5
LLKCIELCCGSVKEM	ATP1A1	456	P05023
ELLECLDLEKSSCCM	MYO18A	1151	Q92614
DPCCQICNVMALEIK	FAM205C	101	A6NFA0
LCKGSLDNMTCILVC	PPM1N	311	Q8N819
GLECSDIEKAVELMC	KALRN	2081	O60229
KENDEMPTCLLCVCL	OGN	86	P20774
CETVCKTGMVLLCGE	MAT1A	56	Q00266
EKQMEVCEVCGAFLI	LUC7L3	186	O95232
VGTKVADCICLMALD	OGG1	246	O15527
ARECCSIVCMAAKEV	KIF25-AS1	61	Q9Y6Z4
RVQLKDMGEDLECLC	EIF4G2	241	P78344
MDAGIICDVCTCELQ	ITGB4	446	P16144
MDHILICCVCLGDNS	PHF14	316	O94880
ADGMSAECECNIKIL	DSG1	246	Q02413
CLDVGLAAMVCKELT	KDM5A	626	P29375
ICKDIMTDAVVIPCC	RBBP6	261	Q7Z6E9
ICRSDGHCIEKMQKC	MALRD1	1056	Q5VYJ5
ELLMNADVICCTCVG	UPF1	616	Q92900
ETQDFEKKLMECCIC	KDM2A	631	Q9Y2K7
VEVIMCVCAEDGKTL	DOCK2	446	Q92608
KEKGICVICMDTISN	DTX3L	556	Q8TDB6
CCLLKVFICQMSEEE	DYM	111	Q7RTS9
ICKMQEVLEECGCSL	EFCAB6	986	Q5THR3
LLSMEAEVCEKIGCL	CEP290	921	O15078
AKCIPCITDCVMAEI	FCF1	96	Q9Y324
CITDCVMAEIEKLGQ	FCF1	101	Q9Y324
CKDINECETPGICMN	FBN1	611	P35555
KAAGVCLMLLATCCE	KPNB1	346	Q14974
TECECMCVLQAKPIS	INSC	86	Q1MX18
SMSELEKVDGLLTCC	DDAH1	261	O94760
SCEENVCRSLKDCEM	PRR14L	1131	Q5THK1
DGEMLCENVKDCTVL	PRR14L	1266	Q5THK1
CCRDLMEEKFDQVCQ	MTOR	361	P42345
EAQIMCSSICKCIGC	TESMIN	386	Q9Y4I5
VVEACCSVLSMVCAD	MAP3K1	631	Q13233
CEMEPCLEGEECKTL	TAFA1	96	Q7Z5A9
CHMQPCLEGEECKVL	TAFA2	96	Q8N3H0
DEQVCCEALEVMTLC	USP9X	1281	Q93008
CDSLCNCEEKDGTML	SLITRK6	31	Q9H5Y7
VAGNCRMCLVEIEKA	NDUFS1	71	P28331
CKICMDSPIDCVLLE	RFFL	316	Q8WZ73
EELIECATGKMELCA	SHCBP1	586	Q8NEM2
CCVCVEAKEGHLSVM	STARD9	4606	Q9P2P6
ACALDQTGLLEMKCC	SEC23B	351	Q15437
DCQDVASECEVKCMP	TXN	61	P10599
CELCLLMTEECTTII	RNF17	56	Q9BXT8
MDLVCPEKCRCEGTI	SLIT3	501	O75094
KLEQSFMCVCCQELV	UHRF2	726	Q96PU4
VIHMEEKPCKCEECG	ZNF99	501	A8MXY4
CKNILACRSEELCME	TNFAIP3	721	P21580
VKQLTDEEECCICMD	RNF141	146	Q8WVD5
VEMCCVSSDNHCKLE	UBE3D	186	Q7Z6J8
GKLQTALKEVEMCVC	PREX2	1031	Q70Z35
MSLECGCTVCLKCIN	RFPL3	51	O75679
VCCEALEVMTLCFAL	USP9Y	1286	O00507
LSECQCGICMEILVE	RNF168	11	Q8IYW5
CGEDCLNRLLMIECS	SETD2	1516	Q9BYW2
GEDCVQLCSEMVTIK	ZNFX1	1391	Q9P2E3
CEKAPKEATVMCEQC	TRIM9	171	Q9C026
EMFCEVDKSLLCLLC	TRIM51G	101	A0A3B3IT33
DCIKEVCLEMLGESA	ZBED9	846	Q6R2W3
QGLLCDCMLVVKGVC	ZBTB49	21	Q6ZSB9
EVLKLFCETCDMLTC	TRIM66	71	O15016
MACSLKDELLCSICL	TRIM62	1	Q9BVG3
CLCLDKVEVEMKTCE	UHRF1BP1	81	Q6BDS2
CKMLVEEEGLQLLCD	ZYG11A	706	Q6WRX3
QVKCIITEEKVCMVC	VPS39	841	Q96JC1
IKAESVCICFIDDCM	VPS13D	2706	Q5THJ4