Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	preribosome, large subunit precursor	ZNF622 MDN1	4.39e-04	21	31	2	GO:0030687
Domain	ZnF_U1	ZFHX2 ZNF622	1.12e-03	29	32	2	SM00451
Domain	Znf_U1	ZFHX2 ZNF622	1.12e-03	29	32	2	IPR003604
Domain	-	TOMM70 TRAPPC8 CLUH	5.25e-03	207	32	3	1.25.40.10
Domain	USP_CS	USP17L7 USP26	5.70e-03	66	32	2	IPR018200
Domain	ConA-like_dom	MEP1A CLSTN1 TRIM9	6.14e-03	219	32	3	IPR013320
Domain	USP_1	USP17L7 USP26	6.39e-03	70	32	2	PS00972
Domain	UCH	USP17L7 USP26	6.57e-03	71	32	2	PF00443
Domain	USP_2	USP17L7 USP26	6.57e-03	71	32	2	PS00973
Domain	USP_3	USP17L7 USP26	6.75e-03	72	32	2	PS50235
Domain	USP_dom	USP17L7 USP26	6.75e-03	72	32	2	IPR028889
Domain	Peptidase_C19_UCH	USP17L7 USP26	6.75e-03	72	32	2	IPR001394
Domain	-	MTMR3 ZNRF3 TRIM9 MAP3K1	6.96e-03	449	32	4	3.30.40.10
Domain	TPR-like_helical_dom	TOMM70 TRAPPC8 CLUH	7.28e-03	233	32	3	IPR011990
Domain	Znf_RING/FYVE/PHD	MTMR3 ZNRF3 TRIM9 MAP3K1	7.51e-03	459	32	4	IPR013083
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	POLRMT TBC1D8 LRIG2 ZNF622 MDN1 TRAPPC8 CLUH VANGL1 BAG2	9.27e-06	1487	34	9	33957083
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TBC1D8 TOMM70 ADGRE5 MDN1 ZNRF3 TRIM9 BAG2	6.31e-05	1061	34	7	33845483
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MTMR3 POLRMT ZNF622 TOMM70 MDN1 CLUH VANGL1 BAG2	7.67e-05	1496	34	8	32877691
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	POLRMT TOMM70 MDN1 CLUH BAG2	1.36e-04	515	34	5	31617661
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	USP26 TOMM70 MDN1 TRAPPC8	1.41e-04	272	34	4	18187620
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	MTMR3 ZBTB39 MDN1	1.45e-04	104	34	3	9205841
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	LRIG2 ZNF622 TOMM70 VANGL1 BAG2	1.60e-04	533	34	5	25544563
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	POLRMT ZNF622 TOMM70 STAMBPL1 BAG2	1.80e-04	547	34	5	37267103
Pubmed	The DNA sequence of human chromosome 22.	MTMR3 ZNF74 CACNA1I ZNRF3	2.05e-04	300	34	4	10591208
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MTMR3 POLRMT LRIG2 TOMM70 CLUH VANGL1	3.27e-04	974	34	6	28675297
Pubmed	A protein interaction landscape of breast cancer.	POLRMT TOMM70 MDN1 CLUH BAG2	3.56e-04	634	34	5	34591612
Pubmed	Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs.	FAM106C FAM106A	3.70e-04	29	34	2	11997339
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	MDN1 CLUH VANGL1 BAG2	6.03e-04	399	34	4	37536630
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	USP17L7 LRRC8C ZNF622 MDN1 TRIM9	7.01e-04	736	34	5	29676528
Interaction	USP17L7 interactions	USP17L7 USP26	3.65e-05	6	32	2	int:USP17L7
Interaction	RHOV interactions	TBC1D8 ZNF622 ADGRE5 MDN1 VANGL1	3.78e-05	243	32	5	int:RHOV
Cytoband	1p13.1	LRIG2 VANGL1	2.77e-04	33	34	2	1p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	LRIG2 ATXN7L2 VANGL1	5.16e-04	211	34	3	chr1p13
Cytoband	Ensembl 112 genes in cytogenetic band chr6p12	MEP1A BAG2	4.99e-03	142	34	2	chr6p12
Cytoband	17p11.2	FAM106C FAM106A	6.22e-03	159	34	2	17p11.2
ToppCell	356C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZFHX2 ADGRE5 CLUH VANGL1	8.16e-06	169	34	4	fec669968a77060bd77ee8695034e35a642c984f
ToppCell	356C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZFHX2 ADGRE5 CLUH VANGL1	8.16e-06	169	34	4	0425d2580ed325178f522c0093ff4623de6ce7a8
Disease	lysophosphatidylethanolamine 20:4 measurement	LRIG2 CACNA1I	3.99e-04	29	30	2	EFO_0010370
Disease	urate measurement, body mass index	TRIM9 MAP3K1	4.27e-04	30	30	2	EFO_0004340, EFO_0004531
Disease	sleep duration, low density lipoprotein cholesterol measurement	TDRD15 ATXN7L2	3.87e-03	91	30	2	EFO_0004611, EFO_0005271
Disease	familial hyperlipidemia	TDRD15 ATXN7L2	5.21e-03	106	30	2	MONDO_0001336

Protein segments in the cluster

Peptide	Gene	Start	Entry
NYHSMESILQHLAFC	VANGL1	416	Q8TAA9
HLMTYLEDTSLCQFH	USP26	656	Q9BXU7
MSTELLANYCHSSLH	FAM106A	86	Q4KMX7
QCSHLSSFAILMAHY	ADGRE5	526	P48960
CSSDKTDMNRHHYSL	CLSTN1	406	O94985
CSALSSMLERHLSTH	ATXN7L2	436	Q5T6C5
MSTELLANYCHSSLH	FAM106C	86	P0CH98
LYSVSCHLHMETSDF	MDN1	1411	Q9NU22
SPVLSHSYCLHQEVM	OR51G2	176	Q8NGK0
ILAICSDSHLHTPMY	OR7C1	46	O76099
AKSHLMSLYSACSSE	BAG2	131	O95816
ATYCHTRLLIHSMCT	CACNA1I	1471	Q9P0X4
TRLLIHSMCTSHYLD	CACNA1I	1476	Q9P0X4
SLDSSHMMLTALHCY	POLRMT	1126	O00411
SRQLSAMSCSSAHLH	MTMR3	971	Q13615
CLNSSPLSHHSQLMF	MAP3K1	966	Q13233
TAHMTLHYDTVCQET	TDRD15	271	B5MCY1
ASSINLIHCSHFESM	SLC26A8	636	Q96RN1
MASLSCLLNYDVSHT	NT5DC3	501	Q86UY8
MYNCTTTHTLLDHCT	MEP1A	256	Q16819
MHLALYCFASSQLST	CLUH	1066	O75153
VSMDAYLNHASICCH	XKRY	111	O14609
SLSSHMSLLHSRNSC	ZFHX2	436	Q9C0A1
LSSVDLHTHCSYQLM	STAMBPL1	356	Q96FJ0
ASLVFHSTSMCSDHR	TBC1D8	411	O95759
MAHLYSLCDAAHAQT	TOMM70	581	O94826
CGHYSSTLNLMSKHV	ZBTB39	666	O15060
VSTCTDHELENHSMY	TRIM9	226	Q9C026
CSLEMNYSSNSSLEH	ZNRF3	661	Q9ULT6
FSCSSLLSMHLRVHT	ZNF74	341	Q16587
FLNHYLACMLVASSS	TRAPPC8	141	Q9Y2L5
NYMLSREDSQTCHLH	USP17L7	106	P0C7H9
ITDCLFCSHHSSSLM	ZNF622	251	Q969S3
FSCNHTMAHLFSKLS	LRRC8C	306	Q8TDW0
SASSMSCHRLQDHAF	LRIG2	1036	O94898