Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP6 LRP1B

1.55e-0516623GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP6 LRP1B

3.64e-0521623GO:0030228
GeneOntologyMolecularFunctionstructural constituent of muscle

NEBL CSRP1 OBSCN

3.22e-0443623GO:0008307
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 NID1 FST

5.34e-0451623GO:0043394
GeneOntologyCellularComponentZ disc

FLNA NEBL SYNE2 CSRP1 OBSCN

7.90e-05151615GO:0030018
GeneOntologyCellularComponentI band

FLNA NEBL SYNE2 CSRP1 OBSCN

1.23e-04166615GO:0031674
GeneOntologyCellularComponentaxonal growth cone

FLNA LRP1 APC

3.07e-0445613GO:0044295
GeneOntologyCellularComponentsarcomere

FLNA NEBL SYNE2 CSRP1 OBSCN

7.96e-04249615GO:0030017
GeneOntologyCellularComponentWnt signalosome

APC LRP6

9.79e-0416612GO:1990909
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

NID1 TNXB

1.11e-0317612GO:0098637
GeneOntologyCellularComponentmyofibril

FLNA NEBL SYNE2 CSRP1 OBSCN

1.20e-03273615GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

FLNA NEBL SYNE2 CSRP1 OBSCN

1.57e-03290615GO:0043292
HumanPhenoHyperlipoproteinemia

UBR1 SYNE2 LRP6 ALB

2.15e-0540224HP:0010980
DomainEGF

NELL1 FCGBP PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

4.22e-092356110SM00181
DomainEGF-like_dom

NELL1 FCGBP PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

7.36e-092496110IPR000742
DomainEGF

PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

7.48e-09126618PF00008
DomainEGF_3

NELL1 PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

6.66e-08235619PS50026
DomainLdl_recept_b

LRP1 LRP6 NID1 LRP1B

1.01e-0714614PF00058
DomainLDLRB

LRP1 LRP6 NID1 LRP1B

1.01e-0714614PS51120
DomainEGF_1

NELL1 PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

1.34e-07255619PS00022
DomainLY

LRP1 LRP6 NID1 LRP1B

1.37e-0715614SM00135
DomainLDLR_classB_rpt

LRP1 LRP6 NID1 LRP1B

1.37e-0715614IPR000033
DomainEGF_CA

NELL1 PAMR1 LRP1 NID1 HABP2 LRP1B NOTCH2

1.39e-07122617SM00179
DomainEGF-like_Ca-bd_dom

NELL1 PAMR1 LRP1 NID1 HABP2 LRP1B NOTCH2

1.55e-07124617IPR001881
DomainEGF-like_CS

NELL1 PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

1.63e-07261619IPR013032
DomainEGF_2

NELL1 PAMR1 LRP1 LRP6 NID1 HABP2 LRP1B TNXB NOTCH2

1.85e-07265619PS01186
Domain-

LRP1 LRP6 NID1 LRP1B

7.77e-06396142.120.10.30
DomainEGF_CA

NELL1 LRP1 NID1 LRP1B NOTCH2

8.94e-0686615PF07645
DomainDUF5050

LRP1 LRP1B

1.05e-052612IPR032485
DomainDUF5050

LRP1 LRP1B

1.05e-052612PF16472
DomainGrowth_fac_rcpt_

NELL1 LRP1 NID1 LRP1B TNXB NOTCH2

1.17e-05156616IPR009030
Domain6-blade_b-propeller_TolB-like

LRP1 LRP6 NID1 LRP1B

1.52e-0546614IPR011042
DomainEGF_Ca-bd_CS

NELL1 LRP1 NID1 LRP1B NOTCH2

1.61e-0597615IPR018097
DomainEGF_CA

NELL1 LRP1 NID1 LRP1B NOTCH2

1.78e-0599615PS01187
DomainASX_HYDROXYL

NELL1 LRP1 NID1 LRP1B NOTCH2

1.87e-05100615PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL1 LRP1 NID1 LRP1B NOTCH2

2.47e-05106615IPR000152
DomainVWC_out

NELL1 FCGBP MUC5AC

3.09e-0519613SM00215
DomaincEGF

LRP1 NID1 LRP1B

8.17e-0526613IPR026823
DomaincEGF

LRP1 NID1 LRP1B

8.17e-0526613PF12662
DomainVWC

NELL1 FCGBP MUC5AC

2.58e-0438613SM00214
DomainLDLR_class-A_CS

LRP1 LRP6 LRP1B

3.00e-0440613IPR023415
DomainVWF_dom

NELL1 FCGBP MUC5AC

3.48e-0442613IPR001007
DomainLdl_recept_a

LRP1 LRP6 LRP1B

4.27e-0445613PF00057
Domain-

LRP1 LRP6 LRP1B

4.55e-04466134.10.400.10
DomainLDLRA_1

LRP1 LRP6 LRP1B

5.16e-0448613PS01209
DomainLDLRA_2

LRP1 LRP6 LRP1B

5.49e-0449613PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP6 LRP1B

5.49e-0449613IPR002172
DomainLDLa

LRP1 LRP6 LRP1B

5.49e-0449613SM00192
DomainFol_N

FCGBP FST

5.66e-0411612IPR003645
DomainFOLN

FCGBP FST

5.66e-0411612SM00274
DomainEGF_3

NELL1 NID1

6.78e-0412612PF12947
DomainTIL

FCGBP MUC5AC

6.78e-0412612PF01826
Domain-

HSPA4L HSPA4

6.78e-04126122.60.34.10
DomainEGF_dom

NELL1 NID1

6.78e-0412612IPR024731
DomainHSP70_peptide-bd

HSPA4L HSPA4

6.78e-0412612IPR029047
DomainC8

FCGBP MUC5AC

6.78e-0412612PF08742
Domain-

HSPA4L HSPA4

8.00e-04136121.20.1270.10
DomainUnchr_dom_Cys-rich

FCGBP MUC5AC

8.00e-0413612IPR014853
DomainHeat_shock_70_CS

HSPA4L HSPA4

8.00e-0413612IPR018181
DomainHSP70_C

HSPA4L HSPA4

8.00e-0413612IPR029048
DomainC8

FCGBP MUC5AC

8.00e-0413612SM00832
DomainTIL_dom

FCGBP MUC5AC

9.31e-0414612IPR002919
DomainEGF_extracell

NELL1 LRP1B TNXB

9.94e-0460613IPR013111
DomainEGF_2

NELL1 LRP1B TNXB

9.94e-0460613PF07974
DomainVWD

FCGBP MUC5AC

1.22e-0316612SM00216
DomainVWF_type-D

FCGBP MUC5AC

1.22e-0316612IPR001846
DomainVWFD

FCGBP MUC5AC

1.22e-0316612PS51233
DomainHSP70

HSPA4L HSPA4

1.22e-0316612PF00012
DomainVWD

FCGBP MUC5AC

1.22e-0316612PF00094
DomainHSP70_2

HSPA4L HSPA4

1.38e-0317612PS00329
DomainHSP70_3

HSPA4L HSPA4

1.38e-0317612PS01036
DomainHSP70_1

HSPA4L HSPA4

1.38e-0317612PS00297
DomainHsp_70_fam

HSPA4L HSPA4

1.55e-0318612IPR013126
DomainActinin_actin-bd_CS

FLNA SYNE2

2.54e-0323612IPR001589
DomainACTININ_2

FLNA SYNE2

2.54e-0323612PS00020
DomainACTININ_1

FLNA SYNE2

2.54e-0323612PS00019
DomainVWC

NELL1 MUC5AC

3.76e-0328612PF00093
DomainVWFC_1

NELL1 MUC5AC

6.15e-0336612PS01208
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF462 FLNA NRIP1 IRS4 OGT ZNF644 FIZ1 LRP1 APC KIAA1958

4.09e-09418631034709266
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

FLNA OGT CSRP1 OBSCN KPRP ALB RALGAPA2 MUC5AC HSPA4

7.91e-0756463921565611
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP6 LRP1B

9.25e-071163324639464
Pubmed

Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.

LRP1 LRP6

3.23e-06263226031789
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

3.23e-06263215963947
Pubmed

Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.

HSPA4L HSPA4

3.23e-06263210524232
Pubmed

Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis.

APC LRP6

3.23e-06263234359960
Pubmed

A panel of a mitogenic (PDGF), biochemical (albumin) and demographic (age) parameters for the non-invasive assessment of hepatic fibrosis.

PDGFA ALB

3.23e-06263230924403
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP6 LRP1B

7.36e-062163321337463
Pubmed

[Effect of osmotic response element binding protein on mucus secretion with hypertonicity in human airway epithelial cells].

MUC5AC HSPA4

9.68e-06363221418859
Pubmed

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.

NRIP1 APC

9.68e-06363224667635
Pubmed

Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.

NID1 ALB NOTCH2

9.78e-062363323386589
Pubmed

The P2Y2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells.

FLNA LRP1

1.93e-05463227522265
Pubmed

TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase.

TRAF1 TNFRSF17

1.93e-05463210903733
Pubmed

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.

LRP1 NOTCH2

1.93e-05463238462037
Pubmed

Morphofunctional studies of the glomerular wall in mice lacking entactin-1.

NID1 ALB

1.93e-05463214566019
Pubmed

The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway.

LRP1 LRP6

1.93e-05463214739301
Pubmed

Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.

OSR2 LRP6 NOTCH2

2.46e-053163330254141
Pubmed

Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene.

IRS4 PDGFA

4.82e-05663210067860
Pubmed

Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.

APC MUC5AC

4.82e-05663216142311
Pubmed

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors.

APC LRP6

4.82e-05663212626757
Pubmed

Suppression of C/EBP alpha expression in biliary cell differentiation from hepatoblasts during mouse liver development.

NID1 ALB

4.82e-05663215519652
Pubmed

New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.

NELL1 IRS4 FST

5.33e-054063319864314
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

FLNA FAM120B IRS4 OGT HSPA4L ALB HSPA4

6.20e-0555163734728620
Pubmed

Cooperation Between MYC and β-Catenin in Liver Tumorigenesis Requires Yap/Taz.

APC ALB

6.74e-05763231965581
Pubmed

A novel HSF1-mediated death pathway that is suppressed by heat shock proteins.

HSPA4L HSPA4

6.74e-05763217024176
Pubmed

Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis.

FLNA NID1

6.74e-05763217172441
Pubmed

DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.

APC LRP6

6.74e-05763229431745
Pubmed

Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System.

LRP1 APC

8.98e-05863227280679
Pubmed

Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.

ALB HSPA4

8.98e-05863221276792
Pubmed

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.

NID1 FST NOTCH2

1.04e-045063324449835
Pubmed

MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.

APC LRP6

1.15e-04963220128690
Pubmed

The role of notch signaling in the development of intrahepatic bile ducts.

ALB NOTCH2

1.15e-04963215578515
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 NID1

1.15e-04963210772929
Pubmed

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

HSPA4L HSPA4

1.44e-041063219171884
Pubmed

Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl).

APC ALB

1.44e-04106327590736
Pubmed

Gsk3β is required in the epithelium for palatal elevation in mice.

PDGFA OSR2

1.44e-041063220981831
Pubmed

The regulation and deregulation of Wnt signaling by PARK genes in health and disease.

APC LRP6

1.44e-041063224115276
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

IRS4 HSPA4L OBSCN HSPA4

1.54e-0414863435676246
Pubmed

Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis.

TTLL6 OSR2

1.76e-041163236825984
Pubmed

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.

FLNA OGT

1.76e-041163233849069
Pubmed

Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice.

HSPA4L HSPA4

2.11e-041263223980576
Pubmed

Heat-shock protein HSPA4 is required for progression of spermatogenesis.

HSPA4L HSPA4

2.11e-041263221487003
Pubmed

Insulin receptor substrate 4 associates with the protein IRAS.

IRS4 HSPA4

2.11e-041263211912194
Pubmed

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.

APC LRP6

2.11e-041263222682247
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DOCK11 HSPA4L APC NID1 ALB HSPA4

2.21e-0447563631040226
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA FAM120B OGT HSPA4L CSRP1 APC SPIRE1 ALB PFN2 HSPA4

2.36e-041431631037142655
Pubmed

Developmental plasticity of epithelial stem cells in tooth and taste bud renewal.

OSR2 FST

2.49e-041363231427537
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ZNF462 NRIP1 SYNE2 OBSCN OSR2 NOTCH2

2.82e-0449763623414517
Pubmed

Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

OSR2 FST

2.90e-041463225645944
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP6

2.90e-041463217389516
Pubmed

Beta-catenin is temporally regulated during normal liver development.

APC ALB

2.90e-041463215057752
Pubmed

Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.

NID1 ALB

2.90e-041463226724533
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP1B

2.90e-041463215082773
Pubmed

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

IRS4 HSPA4

2.90e-041463221151955
Pubmed

Quantitative interaction proteomics of neurodegenerative disease proteins.

OGT SYNE2 OBSCN NID1 HSPA4

3.03e-0432363525959826
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

NRIP1 LRP1 ALB NOTCH2

3.54e-0418463432908313
Pubmed

Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.

NRIP1 IRS4 KPRP

3.62e-047663336560452
Pubmed

Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.

FLNA LRP6

3.81e-041663227789627
Pubmed

A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.

UBR1 STARD9

3.81e-04166327633422
Pubmed

The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.

APC LRP6

3.81e-041663219576224
Pubmed

Modifier genes and protective alleles in humans and mice.

APC NOTCH2

3.81e-041663212787792
Pubmed

The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development.

FST CA8

3.81e-041663228467908
Pubmed

Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.

ALB NOTCH2

3.81e-041663219185577
Pubmed

Local network topology in human protein interaction data predicts functional association.

TRAF1 TNFRSF17

3.81e-041663219641626
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF462 OGT ZNF644 KPRP ALB

4.43e-0435163538297188
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

IRS4 HSPA4L SYNE2 HSPA4

4.58e-0419763420811636
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

FLNA FCGBP NEBL CSRP1 KPRP NID1 ALB PFN2

4.82e-04101663819056867
Pubmed

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution.

APC NOTCH2

4.85e-041863236899896
Pubmed

USP15 Enhances Re-epithelialization Through Deubiquitinating EIF4A1 During Cutaneous Wound Repair.

FLNA ALB

4.85e-041863232671073
Pubmed

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

SYNE2 KPRP

4.85e-041863233361760
Pubmed

Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway.

MUC5AC NOTCH2

5.41e-041963227122169
Pubmed

Lhx2-/- mice develop liver fibrosis.

PDGFA ALB

5.41e-041963215536133
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNA OGT OBSCN LRP1

6.25e-0421463422199357
Pubmed

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

FLNA HSPA4L HSPA4

6.34e-049263323055941
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

TRAF1 APC LRP6 FST NOTCH2

6.57e-0438363519453261
Pubmed

Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa.

FLNA ALB

6.63e-04216326457647
Pubmed

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.

NID1 NOTCH2

6.63e-042163221703454
Pubmed

Notch signaling maintains Leydig progenitor cells in the mouse testis.

PDGFA NOTCH2

6.63e-042163218927153
Pubmed

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.

OGT HSPA4

6.63e-042163212670868
Pubmed

HEY1 functions are regulated by its phosphorylation at Ser-68.

FLNA SYNE2 APC

6.96e-049563327129302
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

TRAF1 OGT KPRP ALB

7.17e-0422263435941108
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

MUC5AC NOTCH2

7.29e-042263234998785
Pubmed

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

FAM120B WDR27

7.29e-042263221980299
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NRIP1 HSPA4L SYNE2 APC ALB

7.80e-0439863535016035
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

HSPA4L HSPA4

7.97e-042363221231916
Pubmed

Role of β-catenin in development of bile ducts.

APC ALB

7.97e-042363226856660
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

NRIP1 ALB

7.97e-042363219737349
Pubmed

Hepatocyte nuclear factor 1β controls nephron tubular development.

OSR2 NOTCH2

7.97e-042363223362349
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

LRP6 FST NOTCH2

8.08e-0410063324859004
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP1B NOTCH2

8.32e-0410163323382219
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

FLNA IRS4 CSRP1

8.80e-0410363321706016
Pubmed

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.

IRS4 HSPA4L ALB HSPA4

9.00e-0423663436339263
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

IRS4 DOCK11 STARD9 SYNE2 APC SPIRE1 NOTCH2

9.23e-0486163736931259
Pubmed

Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ERα) and Biochemical Characterization of the ERα-Hsp70 Interaction.

HSPA4L HSPA4

9.43e-042563227483141
Pubmed

Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis.

OSR2 NOTCH2

1.02e-032663233328221
Pubmed

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

FLNA CSRP1

1.02e-032663223382103
Pubmed

Hes1 in the somatic cells of the murine ovary is necessary for oocyte survival and maturation.

PDGFA FST

1.02e-032663223274689
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

ALB NOTCH2

1.02e-032663219369401
Pubmed

Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.

MUC5AC NOTCH2

1.10e-032763232878924
InteractionDPRX interactions

ZNF644 KPRP ALB

2.08e-0518613int:DPRX
InteractionZNF383 interactions

UBR1 ZNF644 LRP6

2.47e-0519613int:ZNF383
InteractionSULF2 interactions

UBR1 DOCK11 APC LRP1B NOTCH2

3.01e-05119615int:SULF2
InteractionFIZ1 interactions

OGT FIZ1 NOTCH2

4.48e-0523613int:FIZ1
InteractionNTN5 interactions

APC LRP1B NOTCH2

5.10e-0524613int:NTN5
GeneFamilyLow density lipoprotein receptors

LRP1 LRP6 LRP1B

2.61e-0613393634
GeneFamilyHeat shock 70kDa proteins

HSPA4L HSPA4

6.04e-0417392583
CoexpressionBOQUEST_STEM_CELL_UP

OGT PAMR1 LRP1 OSR2 FST LRP1B NOTCH2

2.76e-06261627M1834
CoexpressionVERRECCHIA_EARLY_RESPONSE_TO_TGFB1

LRP1 APC NID1 NOTCH2

8.21e-0654624M4737
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

ZNF462 NRIP1 ZNF142 IRS4 DOCK11 STARD9 SYNE2 LRP1 OSR2 LRP6 NID1

1.35e-057906111gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

ZNF462 NRIP1 IRS4 DOCK11 STARD9 SYNE2 LRP1 OSR2 LRP6 NID1 TNXB

1.50e-057996111gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

ZNF462 FAM120B IRS4 OGT NEBL DOCK11 SYNE2 KIAA1958 PFN2 UNC5D NOTCH2

8.53e-059676111PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

ZNF462 NRIP1 ZNF142 DOCK11 STARD9 SYNE2 LRP1 OSR2 LRP6 NID1

8.70e-058016110gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_200

NRIP1 IRS4 SYNE2 OSR2 NID1

1.15e-04166615gudmap_developingGonad_e18.5_epididymis_200
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500

NRIP1 DOCK11 STARD9 SYNE2 LRP1

1.47e-04175615gudmap_developingGonad_e14.5_ epididymis_500_k4
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500

NRIP1 IRS4 DOCK11 SYNE2 LRP1 OSR2 NID1

1.59e-04406617gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500

NRIP1 DOCK11 STARD9 SYNE2 LRP1 OSR2 NID1

1.77e-04413617gudmap_developingGonad_e14.5_ epididymis_500
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 FST TNXB

2.99e-071946263d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 OSR2 NID1 FST TNXB

2.99e-07194626ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB CA8

3.18e-07196626ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

FLNA PAMR1 LRP1 OSR2 NID1 TNXB

3.58e-072006269d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 OSR2 NID1 FST TNXB

3.58e-07200626f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP NEBL FST LRP1B MGAM2

3.21e-06163625be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL1 FLNA CSRP1 FAM227A NID1

4.30e-06173625f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 LRP1 OSR2 FST NOTCH2

4.42e-061746259c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 LRP1 OSR2 FST NOTCH2

4.42e-06174625bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 NEBL DOCK11 ASIC5 UNC5D

4.67e-06176625327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL1 FLNA STARD9 FAM227A NID1

4.81e-06177625e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP HABP2 MUC5AC ZMYND12 CA8

4.81e-061776252af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 LRP1 OSR2 FST TNXB

5.22e-06180625c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 STARD9 CSRP1 NID1 CA8

5.22e-06180625280ff5c8f292be1b88120db5ff1788b750644856
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 LRP1 OSR2 FST TNXB

5.22e-0618062532c6a3886428d82fb4355d987c6d2645f333447b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 STARD9 CSRP1 NID1 CA8

5.22e-06180625fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 NEBL DOCK11 ASIC5 UNC5D

5.50e-061826255e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 OSR2 NID1 TNXB CA8

5.96e-0618562501bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCellP03|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA OGT NEBL CSRP1 NID1

5.96e-06185625a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCellfacs-Trachea-nan-24m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

6.28e-0618762571385068e3fd0bfa7822ae176113a49460c8636b
ToppCellfacs-Trachea-nan-24m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

6.28e-06187625b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCellfacs-Trachea-nan-24m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

6.28e-06187625e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA CSRP1 LRP1 NID1 FST

6.61e-061896259e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 NEBL DOCK11 SYNE2 UNC5D

6.61e-06189625904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 TNXB

6.61e-06189625bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

6.61e-0618962556f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLNA NEBL LRP1 NID1 NOTCH2

6.61e-061896250c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA PAMR1 CSRP1 NID1 FST

6.78e-061906252e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA PAMR1 CSRP1 NID1 FST

6.78e-061906250028f886c789ba238c031eae5d96acaed4af8c25
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 TNXB

6.78e-06190625f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 TNXB

6.78e-06190625c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 TNXB

6.78e-0619062547077579496c5340e99f61499427a3a36b566da3
ToppCelldroplet-Mammary_Gland-nan-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 OSR2 NID1 TNXB

6.96e-061916258022059e434fd411dc539819f969bd4f94861281
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 NEBL DOCK11 SYNE2 UNC5D

6.96e-06191625d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

6.96e-061916251caf726bd07fdca389e678fc16304a6ef1790423
ToppCell(2)_Fibroblasts-(21)_Fibro-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PAMR1 LRP1 OSR2 TNXB CA8

6.96e-061916255ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

6.96e-061916253d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.14e-06192625321850b0f881420c2d57d3e825e365c82fa511ab
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.14e-06192625fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

7.14e-06192625beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.14e-061926257a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.14e-06192625cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCellfacs-Trachea-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.14e-06192625e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCellfacs-Heart-RV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 NID1 FST TNXB NOTCH2

7.32e-0619362576f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCellMesenchymal_cells-Endosteal_fibro.|Mesenchymal_cells / Lineage and Cell class

PAMR1 LRP1 OSR2 NID1 TNXB

7.50e-061946259a4b5de4d1d8a0aa76fed7b36548ea628f3009cc
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA TRAF1 OSR2 NID1 TNXB

7.50e-06194625775600880bb77781de48085d8744c1030223de1f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

7.50e-06194625240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 LRP1 NID1 FST TNXB

7.50e-0619462502b8102be9414d6964cd71019613edff6d88b893
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

7.50e-06194625ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA TRAF1 OSR2 NID1 TNXB

7.50e-0619462504ecb609d233a4b12e275c604810937830363e17
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

7.69e-06195625d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

PAMR1 LRP1 NID1 TNXB NOTCH2

7.69e-06195625f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA PAMR1 NRTN CSRP1 FST

7.69e-06195625bff7685784688425bebd78b0f284a6d4475a9415
ToppCellMesenchymal_cells-Endosteal_fibro.|World / Lineage and Cell class

PAMR1 LRP1 OSR2 NID1 TNXB

7.69e-06195625d53974d1866e23c894ffd492ea11d20422919b11
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 CSRP1 LRP1 NID1 CA8

7.69e-0619562544d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

7.89e-0619662565f2f51e17f1869f3468813127b96d3048d8ad41
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 LRP1 NID1 FST TNXB

7.89e-06196625d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

7.89e-06196625e4ed897900a6472738bc6be2fb4817192727225d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNA PDGFA CSRP1 NID1 FST

7.89e-06196625ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCellfacs-SCAT-Fat-18m-Mesenchymal|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LRP1 NID1 FST TNXB

7.89e-061966252cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNA PDGFA CSRP1 NID1 FST

7.89e-0619662570b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

AJAP1 STARD9 SYNE2 RALGAPA2 LRP1B

7.89e-061966254ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellPND01-Mesenchymal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEBL PAMR1 CSRP1 LRP1 NID1

8.08e-06197625292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEBL TTLL6 FAM227A HABP2 ALB

8.08e-061976256e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNA PAMR1 LRP1 NID1 TNXB

8.49e-0619962538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NELL1 LRP1 NID1 FST TNXB

8.49e-0619962530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL1 FLNA CSRP1 NID1 PFN2

8.49e-061996253d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NELL1 PAMR1 LRP1 NID1 TNXB

8.49e-061996256b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NELL1 LRP1 NID1 FST TNXB

8.70e-062006259b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

FLNA PAMR1 CSRP1 OSR2 NID1

8.70e-06200625c5e051f1aac8dda376c342a9932785a23450e073
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

NELL1 CSRP1 LRP1 NID1 TNXB

8.70e-0620062564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 NID1 FST TNXB

8.70e-06200625db6281b5d4032116310db379d9175d790994c99c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 OSR2 NID1 TNXB

8.70e-06200625cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 NID1 FST TNXB

8.70e-062006256f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNA PAMR1 CSRP1 NID1 TNXB

8.70e-0620062587827041663013f5e7273168dc8709d69840e7ce
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAMR1 CSRP1 APC LRP1B NOTCH2

8.70e-0620062507d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAMR1 CSRP1 APC LRP1B NOTCH2

8.70e-06200625d0812817ef99608994193787a62d39adeb2070ca
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZNF462 FLNA LRP1 NID1 TNXB

8.70e-0620062509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 NID1 FST TNXB

8.70e-0620062510f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell3'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 OSR2 NID1 TNXB

8.70e-0620062587177c973e722ac7d9ee503b9cfacd84fc67865d
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CSRP1 LRP1 NID1 FST TNXB

8.70e-0620062544a68bacdb3d5bf563bd35952176995850933a81
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

LRP1 OSR2 NID1 FST TNXB

8.70e-06200625f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

STARD9 LRP1 OSR2 NID1 TNXB

8.70e-062006253dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

ZNF462 PAMR1 LRP1 NID1 TNXB

8.70e-06200625a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 OSR2 NID1 TNXB

8.70e-06200625cbf6a6c3db88bac37bd084a3a914b12b3af524eb
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

FLNA PAMR1 CSRP1 NID1 TNXB

8.70e-0620062502cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

NELL1 CSRP1 LRP1 NID1 TNXB

8.70e-06200625a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LRP1 NID1 FST TNXB

8.70e-06200625a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CSRP1 LRP1 NID1 FST TNXB

8.70e-06200625dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAMR1 CSRP1 APC LRP1B NOTCH2

8.70e-06200625cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK11 LRP1 LRP6 NID1 NOTCH2

8.70e-06200625bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

NRIP1 SYNE2 APC NID1

4.12e-05138624817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FCGBP ALB LRP1B CA8

6.00e-051526241b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL DOCK11 SEMA4A UNC5D

6.15e-05153624d6526d17826470534b766df144c74e73eb83fdad
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KPRP ASIC5 LRP1B UNC5D

7.68e-05162624bf886e22ff2a20353499004b53f25fb9e6574896
ComputationalGenes in the cancer module 202.

FLNA NEBL PFN2

1.58e-0428413MODULE_202
Diseasephosphatidylcholine measurement

NELL1 LINC01559 SYNE2 ABHD3 ALB TNXB UNC5D

2.22e-06284627EFO_0010226
Diseasecoronary artery calcification

ZNF462 LINC01559 STARD9 LRP6 WDR27 LRP1B HSPA4

4.37e-05450627EFO_0004723
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

NELL1 MUC5AC

1.55e-049622EFO_0009824
Diseasegallbladder cancer (is_implicated_in)

APC LRP1B

3.34e-0413622DOID:3121 (is_implicated_in)
DiseaseHereditary Diffuse Gastric Cancer

FCGBP APC ALB FST NOTCH2

3.80e-04293625C1708349
DiseaseMalignant neoplasm of breast

FLNA NRIP1 PDGFA ZNF644 SYNE2 OBSCN PHF7 FST NOTCH2

3.88e-041074629C0006142
DiseaseStomach Neoplasms

FCGBP APC ALB FST NOTCH2

4.04e-04297625C0038356
DiseaseMalignant neoplasm of stomach

FCGBP APC ALB FST NOTCH2

4.23e-04300625C0024623
Diseaseurate measurement

NEBL LRP1 FRMD8 NID1 PHF7 HABP2 FST NOTCH2

5.51e-04895628EFO_0004531
Diseasesphingomyelin 14:0 measurement

SYNE2 NID1

5.79e-0417622EFO_0010390
Diseaseresponse to anticonvulsant

NELL1 NEBL NID1

7.72e-0485623GO_0036277
DiseaseCraniosynostosis

ZNF462 NELL1

8.05e-0420622C0010278
Diseasecholangiocarcinoma (is_implicated_in)

APC ALB

9.77e-0422622DOID:4947 (is_implicated_in)
DiseaseLiver Failure, Acute

ALB FST

1.16e-0324622C0162557
Diseasediabetes mellitus (implicated_via_orthology)

OGT LRP1

1.37e-0326622DOID:9351 (implicated_via_orthology)
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC SEMA4A

1.37e-0326622C0009405
DiseaseEarly Pregnancy Loss

TRAF1 HABP2 FST

1.58e-03109623C3830362
DiseaseMiscarriage

TRAF1 HABP2 FST

1.58e-03109623C4552766
DiseaseSpontaneous abortion

TRAF1 HABP2 FST

1.58e-03109623C0000786
DiseaseAbortion, Tubal

TRAF1 HABP2 FST

1.58e-03109623C0000822
DiseaseHereditary Nonpolyposis Colorectal Cancer

APC SEMA4A

1.70e-0329622C1333990
Diseasecolorectal cancer (implicated_via_orthology)

APC NOTCH2

1.82e-0330622DOID:9256 (implicated_via_orthology)
Diseaseright ventricular ejection fraction measurement

OBSCN HSPA4

1.82e-0330622EFO_0021816

Protein segments in the cluster

PeptideGeneStartEntry
DCTPTYTDVISETLC

FAM227A

461

F5H4B4
TYETTLEKCCAAADP

ALB

376

P02768
YDVCATIDQCPTRIE

FAM78B

21

Q5VT40
CSHECVRASVPVYTD

AJAP1

356

Q9UKB5
TPRTYCCANTEDLET

ABHD3

186

Q8WU67
AQPCCRPTAYEDEVS

NRTN

161

Q99748
AYCDVPNVSCDIAAS

NOTCH2

1096

Q04721
CRIAPTEYTCEDNVN

LRP1B

3796

Q9NZR2
IANEYSDRCTPACIS

HSPA4

26

P34932
CYPDDPTASEESCRQ

MGAM2

916

Q2M2H8
VLAARYPCDVEDCEA

FRMD8

156

Q9BZ67
ADVDECSTTFPCSQR

LRP1

2981

Q07954
SERCPRCSQAVYAAE

CSRP1

116

P21291
RTCYDIDECSEQPSV

NID1

706

P14543
PCSTDVCDSDYAPSR

LRP6

1531

O75581
DESSYSNCVPIDLSC

NRIP1

431

P48552
YTFCESPRSVQCRAE

MUC5AC

1986

P98088
EPVCASDNATYASEC

FST

281

P19883
ERTHTDERPYTCDIC

OSR2

191

Q8N2R0
EEPNEYARCIAVCSL

RALGAPA2

1151

Q2PPJ7
DCVPGYIRVDDFSCT

NELL1

461

Q92832
EYSCVCGEERTSASL

OBSCN

3341

Q5VST9
CSVIRDSLYVDGDCT

PFN2

71

P35080
CDVSACSAQDVAYPE

HABP2

271

Q14520
ECVPVDLSNCITSSY

DOCK11

591

Q5JSL3
CLAEETAPYESNEAC

FCGBP

5036

Q9Y6R7
DLEDGTCRVTYCPTE

FLNA

2096

P21333
SPNYVVCRDCEVTND

CA8

71

P35219
YESCCPTSREAAVEA

FEM1A

286

Q9BSK4
SLPELYCCEERSSFE

C1orf100

126

Q5SVJ3
SSCPVSCEEIEYPAT

ASIC5

371

Q9NY37
AAAEPSEDTLYQCDC

FIZ1

321

Q96SL8
APCQSEVSYVQCEAS

KPRP

111

Q5T749
TAAVCVYPARVCDAV

DERA

96

Q9Y315
DTCPYFSISELCLES

FAM120B

186

Q96EK7
EAEDCYNTALRLCPT

OGT

311

O15294
AIYEEITACSSSPCF

PAMR1

231

Q6UXH9
ETGRIYVVDPFSECC

IRS4

1041

O14654
CLLPSSEEDYSCTQA

SYNE2

6851

Q8WXH0
ECEECSPAAATDYIP

PHF7

296

Q9BWX1
RVPRANCSVYESCVD

SEMA4A

491

Q9H3S1
AAYADELVRCPSCSF

RNF216

596

Q9NWF9
SYCETLLEPECSSRV

STARD9

2576

Q9P2P6
TYCVEDTPICFSRCS

APC

1261

P25054
YLLCVPDEDTSCSTI

LINC01559

21

Q495D7
TNPREYAACSLDDCI

ERVK-25

926

P63136
SELTCSICTDYLTDP

TRIM77

11

I1YAP6
ECACATTSLNPDYRE

PDGFA

176

P04085
IANEYSDRCTPACIS

HSPA4L

26

O95757
QSSRSLEEFCYPVEC

SPIRE1

541

Q08AE8
YVSEDCSIRTCPSNC

TNXB

611

P22105
GETTYSCRDCAIDPT

UBR1

106

Q8IWV7
VAGDLEVDCYRAPCS

TRAF1

156

Q13077
EVDCYRAPCSESQEE

TRAF1

161

Q13077
TSYSRPCTDNLDDIC

TTLL6

246

Q8N841
EDESTSCYCLLDPFA

UNC5D

651

Q6UXZ4
EAPAERVCAACTVTY

ZMYND12

21

Q9H0C1
TRYTEDCFSDSNCVP

ZNF644

301

Q9H582
DTSRPYECSECEITF

ZNF212

311

Q9UDV6
TVVVYDCDVCSFASP

ZNF462

1026

Q96JM2
DTYACPVCREEFRLS

ZNF142

251

P52746
SSCAREAYPVECAVP

WDR27

486

A2RRH5
PRGLEYTVEECTCED

TNFRSF17

116

Q02223
TRDSCDFSYCSEPSE

KIAA1958

116

Q8N8K9
DRSEISEIYPSFSCC

NEBL

896

O76041
SEIYPSFSCCSEVTR

NEBL

901

O76041