Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity, coupled via Gi/Go

DRD2 DRD3

5.61e-053872GO:0001591
GeneOntologyMolecularFunctionpancreatic polypeptide receptor activity

NPY4R2 NPY4R

1.12e-044872GO:0001602
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity

DRD2 DRD3

1.86e-045872GO:0004952
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN2A SCN5A SCN9A

1.93e-0426873GO:0005248
GeneOntologyBiologicalProcessresponse to histamine

DRD2 DRD3 HRH1

1.50e-0512863GO:0034776
GeneOntologyBiologicalProcessresponse to morphine

DRD2 DRD3 ADCY8

3.07e-0515863GO:0043278
GeneOntologyBiologicalProcessresponse to isoquinoline alkaloid

DRD2 DRD3 ADCY8

3.77e-0516863GO:0014072
GeneOntologyBiologicalProcessepithelial cell differentiation involved in kidney development

LHX1 ASXL1 AMPD2 EDNRA

4.38e-0547864GO:0035850
GeneOntologyBiologicalProcesspositive regulation of cytokinesis

CUL3 DRD2 DRD3 CDC6

8.17e-0555864GO:0032467
GeneOntologyBiologicalProcesscell differentiation involved in kidney development

LHX1 ASXL1 AMPD2 EDNRA

9.40e-0557864GO:0061005
GeneOntologyBiologicalProcesspodocyte differentiation

ASXL1 AMPD2 EDNRA

1.02e-0422863GO:0072112
GeneOntologyBiologicalProcessglomerular epithelial cell differentiation

ASXL1 AMPD2 EDNRA

1.02e-0422863GO:0072311
GeneOntologyBiologicalProcessrenal filtration cell differentiation

ASXL1 AMPD2 EDNRA

1.02e-0422863GO:0061318
GeneOntologyBiologicalProcessnegative regulation of dopamine receptor signaling pathway

DRD2 DRD3

1.03e-044862GO:0060160
GeneOntologyBiologicalProcessglomerular epithelium development

ASXL1 AMPD2 EDNRA

1.17e-0423863GO:0072010
GeneOntologyBiologicalProcessnephron epithelium development

LHX1 ASXL1 AMPD2 KIF26B EDNRA

1.98e-04128865GO:0072009
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

DRD2 DRD3 TRPC1 HRH1 EDNRA

2.37e-04133865GO:0007200
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting dopamine receptor signaling pathway

DRD2 DRD3

2.55e-046862GO:0007195
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN2A SCN5A SCN9A

4.38e-0517863GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN2A SCN5A SCN9A

2.27e-0429863GO:0034706
MousePhenoabnormal nervous system electrophysiology

CUL3 PTCHD1 DRD2 TRPC1 SCN2A SBF2 SCN5A SCN9A STMN2 TAFA4 PDE10A ADCY8

3.11e-083296512MP:0002272
MousePhenoabnormal single cell response

PTCHD1 DRD2 TRPC1 SCN9A ADCY8

5.42e-0735655MP:0003463
MousePhenoabnormal action potential

SCN2A SBF2 SCN5A SCN9A STMN2 TAFA4 PDE10A

2.65e-06133657MP:0005402
DomainARM-type_fold

SMG1 ATR COPG1 XPO6 IFT172 EIF4G1 ASPM TAF2 ARMH3 HEATR3 ARMC8

3.86e-073398511IPR016024
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

1.80e-066853PF11933
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

1.80e-066853IPR024583
DomainNa_channel_asu

SCN2A SCN5A SCN9A

1.07e-0510853IPR001696
DomainNa_trans_assoc

SCN2A SCN5A SCN9A

1.07e-0510853IPR010526
DomainNa_trans_assoc

SCN2A SCN5A SCN9A

1.07e-0510853PF06512
DomainHEAT_REPEAT

SMG1 ATR COPG1 HEATR3 ARMC8

1.66e-0570855PS50077
DomainNPY4_rcpt

NPY4R2 NPY4R

2.05e-052852IPR001933
DomainDopamine_rcpt

DRD2 DRD3

2.03e-045852IPR000929
DomainFATC

SMG1 ATR

2.03e-045852PF02260
DomainARM-like

SMG1 ATR COPG1 XPO6 ASPM HEATR3 ARMC8

2.31e-04270857IPR011989
DomainFAT

SMG1 ATR

3.03e-046852PS51189
DomainFATC

SMG1 ATR

3.03e-046852PS51190
DomainFATC_dom

SMG1 ATR

3.03e-046852IPR003152
DomainPIK_FAT

SMG1 ATR

3.03e-046852IPR014009
DomainFATC

SMG1 ATR

3.03e-046852SM01343
DomainIQ

SCN2A SCN5A SCN9A ASPM

5.09e-0481854SM00015
Domain-

ATR COPG1 XPO6 ASPM HEATR3 ARMC8

5.28e-042228561.25.10.10
DomainNPY_rcpt

NPY4R2 NPY4R

7.22e-049852IPR000611
DomainIQ_motif_EF-hand-BS

SCN2A SCN5A SCN9A ASPM

7.58e-0490854IPR000048
DomainIQ

SCN2A SCN5A SCN9A ASPM

8.57e-0493854PS50096
Domain7TM_GPCR_Srsx

DRD2 DRD3 MC5R HRH1

1.71e-03112854SM01381
DomainMyotubularin-like_Pase_dom

MTMR12 SBF2

1.80e-0314852IPR010569
DomainPPASE_MYOTUBULARIN

MTMR12 SBF2

1.80e-0314852PS51339
DomainMyotubularin_fam

MTMR12 SBF2

1.80e-0314852IPR030564
DomainMyotub-related

MTMR12 SBF2

1.80e-0314852PF06602
DomainIon_trans_dom

TRPC1 SCN2A SCN5A SCN9A

1.82e-03114854IPR005821
DomainIon_trans

TRPC1 SCN2A SCN5A SCN9A

1.82e-03114854PF00520
DomainPI3/4_kinase_CS

SMG1 ATR

2.07e-0315852IPR018936
DomainChannel_four-helix_dom

SCN2A SCN5A SCN9A

2.23e-0357853IPR027359
Domain-

SCN2A SCN5A SCN9A

2.23e-03578531.20.120.350
Domain-

SMG1 ATR

2.36e-03168521.10.1070.11
DomainPI3Kc

SMG1 ATR

2.36e-0316852SM00146
DomainPI3/4_kinase_cat_dom

SMG1 ATR

2.99e-0318852IPR000403
DomainPI3_PI4_kinase

SMG1 ATR

2.99e-0318852PF00454
DomainPI3_4_KINASE_3

SMG1 ATR

2.99e-0318852PS50290
DomainPI3_4_KINASE_1

SMG1 ATR

2.99e-0318852PS00915
DomainPI3_4_KINASE_2

SMG1 ATR

2.99e-0318852PS00916
DomainDAPIN

NLRP9 NLRP8

4.46e-0322852PS50824
DomainPYRIN

NLRP9 NLRP8

4.46e-0322852PF02758
DomainDAPIN

NLRP9 NLRP8

4.46e-0322852IPR004020
DomainPYRIN

NLRP9 NLRP8

4.46e-0322852SM01289
DomainNACHT

NLRP9 NLRP8

4.87e-0323852PS50837
DomainNACHT_NTPase

NLRP9 NLRP8

4.87e-0323852IPR007111
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD2 DRD3 NPY4R MC5R HRH1 GPR45 EDNRA

7.18e-05260567M39397
PathwayREACTOME_DOPAMINE_RECEPTORS

DRD2 DRD3

1.54e-045562M27301
PathwayREACTOME_DOPAMINE_RECEPTORS

DRD2 DRD3

1.54e-045562MM15007
PathwayREACTOME_SIGNALING_BY_GPCR

DRD2 DRD3 NPY4R MC5R HRH1 CCL20 PDE10A ADCY8 GPR45 EDNRA

2.01e-046465610MM14962
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN2A SCN5A SCN9A

2.47e-0431563M877
PathwayWP_MONOAMINE_GPCRS

DRD2 DRD3 HRH1

2.47e-0431563MM15871
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN2A SCN5A SCN9A

2.71e-0432563M27455
PathwayWP_MONOAMINE_GPCRS

DRD2 DRD3 HRH1

2.98e-0433563M39585
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD2 DRD3 NPY4R MC5R HRH1 CCL20 EDNRA

3.13e-04330567M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD2 DRD3 NPY4R MC5R HRH1 CCL20 EDNRA

3.31e-04333567MM14963
PathwayREACTOME_SIGNALING_BY_GPCR

DRD2 DRD3 NPY4R MC5R HRH1 CCL20 PDE10A ADCY8 GPR45 EDNRA

3.91e-047025610M746
PathwayREACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS

ATR CDC6 RFC3

4.19e-0437563M11153
PathwayREACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

GAPVD1 RAB3GAP2 SBF2 CHM

4.43e-0490564M27779
PathwayREACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

GAPVD1 RAB3GAP2 SBF2 CHM

4.62e-0491564MM15518
PathwayPID_ATR_PATHWAY

ATR CDC6 RFC3

4.90e-0439563M46
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

DRD2 DRD3 HRH1

6.11e-0442563M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

DRD2 DRD3 HRH1

6.11e-0442563MM14971
PathwayWP_GPCRS_NONODORANT

DRD2 DRD3 NPY4R MC5R HRH1 EDNRA

6.28e-04266566MM15843
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

DRD2 DRD3 NPY4R MC5R HRH1 EDNRA

7.06e-04272566M13380
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD3 NPY4R MC5R HRH1 GPR45

8.39e-04186565MM15994
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN2A SCN5A SCN9A

1.26e-06987316382098
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN2A SCN5A SCN9A

4.25e-061387315123669
Pubmed

Dissociation of heterotrimeric g proteins in cells.

DRD2 DRD3 NPY4R HRH1 CCL20 EDNRA

6.11e-0617987618577758
Pubmed

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation.

ATR CDC6

6.19e-06287222179839
Pubmed

Striatal dopamine D2/3 receptor availability increases after long-term bariatric surgery-induced weight loss.

DRD2 DRD3

6.19e-06287227184782
Pubmed

N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane.

DRD2 DRD3

6.19e-06287225289757
Pubmed

Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression.

DRD2 DRD3

6.19e-06287212834818
Pubmed

Mapping the landscape of human dopamine D2/3 receptors with [11C]raclopride.

DRD2 DRD3

6.19e-06287231444615
Pubmed

Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa.

DRD2 DRD3

6.19e-06287223154100
Pubmed

Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation.

DRD2 DRD3

6.19e-06287222970199
Pubmed

Association of novelty seeking scores and striatal dopamine D₂/D₃ receptor availability of healthy volunteers: single photon emission computed tomography with ¹²³i-iodobenzamide.

DRD2 DRD3

6.19e-06287220970071
Pubmed

Variability in Action Selection Relates to Striatal Dopamine 2/3 Receptor Availability in Humans: A PET Neuroimaging Study Using Reinforcement Learning and Active Inference Models.

DRD2 DRD3

6.19e-06287232083297
Pubmed

ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells.

ATR CDC6

6.19e-06287219154794
Pubmed

Posterior dopamine D2/3 receptors and brain network functional connectivity.

DRD2 DRD3

6.19e-06287228700819
Pubmed

Decreased c-fos responses to dopamine D(1) receptor agonist stimulation in mice deficient for D(3) receptors.

DRD2 DRD3

6.19e-06287210506202
Pubmed

DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder.

DRD2 DRD3

6.19e-06287223683269
Pubmed

Palmitoylation on the carboxyl terminus tail is required for the selective regulation of dopamine D2 versus D3 receptors.

DRD2 DRD3

6.19e-06287227349735
Pubmed

Effects of the DRD3 Ser9Gly polymorphism on aripiprazole efficacy in schizophrenic patients as modified by clinical factors.

DRD2 DRD3

6.19e-06287219302829
Pubmed

Cerebral morphology and dopamine D2/D3 receptor distribution in humans: a combined [18F]fallypride and voxel-based morphometry study.

DRD2 DRD3

6.19e-06287219457373
Pubmed

Signaling pathways leading to phosphorylation of Akt and GSK-3β by activation of cloned human and rat cerebral D₂and D₃ receptors.

DRD2 DRD3

6.19e-06287220952497
Pubmed

G protein coupling and ligand selectivity of the D2L and D3 dopamine receptors.

DRD2 DRD3

6.19e-06287218218829
Pubmed

Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation.

DRD2 DRD3

6.19e-06287218410503
Pubmed

Association study of dopamine D2, D3 receptor gene polymorphisms with motor fluctuations in PD.

DRD2 DRD3

6.19e-06287211425949
Pubmed

Cortical dopamine D2/D3 receptors and verbal memory in man.

DRD2 DRD3

6.19e-06287220188195
Pubmed

Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake.

DRD2 DRD3

6.19e-06287225511804
Pubmed

Dopamine D2 receptors preferentially regulate the development of light responses of the inner retina.

DRD2 DRD3

6.19e-06287225393815
Pubmed

The dopamine D2 receptors in high-affinity state and D3 receptors in schizophrenia: a clinical [11C]-(+)-PHNO PET study.

DRD2 DRD3

6.19e-06287218987627
Pubmed

Roles of conserved intracellular sequences regions for the proper expression of dopamine D(2) and D(3) receptors.

DRD2 DRD3

6.19e-06287218481021
Pubmed

The candidate gene approach in alcoholism: are there gender-specific differences?

DRD2 DRD3

6.19e-06287214628173
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

6.19e-06287226861708
Pubmed

Cyr61/CCN1 induces CCL20 production by keratinocyte via activating p38 and JNK/AP-1 pathway in psoriasis.

CCN1 CCL20

6.19e-06287228602508
Pubmed

Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase.

DRD2 DRD3

6.19e-06287215102843
Pubmed

DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis.

DRD2 DRD3

6.19e-06287231538542
Pubmed

Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity.

DRD2 DRD3

6.19e-06287222776462
Pubmed

Exploring personality traits related to dopamine D2/3 receptor availability in striatal subregions of humans.

DRD2 DRD3

6.19e-06287226944295
Pubmed

Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients.

DRD2 DRD3

6.19e-06287216959057
Pubmed

Fluorescent ligands for dopamine D2/D3 receptors.

DRD2 DRD3

6.19e-06287233318558
Pubmed

[123I]epidepride binding to cerebellar dopamine D2/D3 receptors is displaceable: implications for the use of cerebellum as a reference region.

DRD2 DRD3

6.19e-06287217175177
Pubmed

Dopamine Receptor Signaling in MIN6 β-Cells Revealed by Fluorescence Fluctuation Spectroscopy.

DRD2 DRD3

6.19e-06287227508444
Pubmed

Dopamine D2 (DAD2) and dopamine D3 (DAD3) receptor gene polymorphisms and treatment outcome in alcohol dependence.

DRD2 DRD3

6.19e-06287212811641
Pubmed

Effects of smoking on D₂/D₃ striatal receptor availability in alcoholics and social drinkers.

DRD2 DRD3

6.19e-06287223649848
Pubmed

Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells.

DRD2 DRD3

6.19e-0628728666994
Pubmed

Distinct genetic patterns of shared and unique genes across four neurodevelopmental disorders.

STXBP1 SCN2A

6.19e-06287232929885
Pubmed

[11 C]raclopride positron emission tomography study of dopamine-D2/3 receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects.

DRD2 DRD3

6.19e-06287231943514
Pubmed

Association Study Between DRD2, DRD3 Genetic Polymorphisms and Adverse Reactions in Chinese Patients on Amisulpride Treatment.

DRD2 DRD3

6.19e-06287239187246
Pubmed

Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D2 and D3 Receptors.

DRD2 DRD3

6.19e-06287227379794
Pubmed

Dopamine D2/3 Binding Potential Modulates Neural Signatures of Working Memory in a Load-Dependent Fashion.

DRD2 DRD3

6.19e-06287230478031
Pubmed

Striatal dopamine D2/3 receptor binding following dopamine depletion in subjects at Ultra High Risk for psychosis.

DRD2 DRD3

6.19e-06287222591910
Pubmed

Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence.

DRD2 DRD3

6.19e-06287216094250
Pubmed

In vivo mesolimbic D2/3 receptor binding predicts posttherapeutic clinical responses in restless legs syndrome: a positron emission tomography study.

DRD2 DRD3

6.19e-06287222234337
Pubmed

Extrastriatal dopamine D 2/3 receptor density and distribution in drug-naive schizophrenic patients.

DRD2 DRD3

6.19e-06287212740603
Pubmed

Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).

DRD2 DRD3

6.19e-06287219011428
Pubmed

Association between DRD2 and DRD3 gene polymorphisms and gastrointestinal symptoms induced by levodopa therapy in Parkinson's disease.

DRD2 DRD3

6.19e-06287227779245
Pubmed

No association of dopamine receptor sensitivity in vivo with genetic predisposition for alcoholism and DRD2/DRD3 gene polymorphisms in alcohol dependence.

DRD2 DRD3

6.19e-06287216759339
Pubmed

-141C Ins/Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population.

DRD2 DRD3

6.19e-06287218496209
Pubmed

Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention.

DRD2 DRD3

6.19e-06287215537671
Pubmed

Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.

DRD2 DRD3

6.19e-06287221663922
Pubmed

Frontal D2/3 Receptor Availability in Schizophrenia Patients Before and After Their First Antipsychotic Treatment: Relation to Cognitive Functions and Psychopathology.

DRD2 DRD3

6.19e-06287226819282
Pubmed

The effect of haloperidol on D2 dopamine receptor subtype mRNA levels in the brain.

DRD2 DRD3

6.19e-0628728313980
Pubmed

Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients.

DRD2 DRD3

6.19e-06287219396436
Pubmed

Association of dopamine D2/3 receptor binding potential measured using PET and [11C]-(+)-PHNO with post-mortem DRD2/3 gene expression in the human brain.

DRD2 DRD3

6.19e-06287232818617
Pubmed

The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors.

DRD2 DRD3

6.19e-06287229337986
Pubmed

Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain.

DRD2 DRD3

6.19e-06287222573693
Pubmed

Dopamine D2/3 receptor availability and amphetamine-induced dopamine release in obesity.

DRD2 DRD3

6.19e-06287224785761
Pubmed

New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion.

DRD2 DRD3

6.19e-06287230626912
Pubmed

Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors.

DRD2 DRD3

6.19e-06287210391470
Pubmed

D2/D3 dopamine receptor binding with [F-18]fallypride correlates of executive function in medication-naïve patients with schizophrenia.

DRD2 DRD3

6.19e-06287228576546
Pubmed

Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson's disease.

DRD2 DRD3

6.19e-06287219669131
Pubmed

Elevation of dopamine induced by cigarette smoking: novel insights from a [11C]-+-PHNO PET study in humans.

DRD2 DRD3

6.19e-06287223954846
Pubmed

Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence.

DRD2 DRD3

6.19e-06287227634830
Pubmed

Contribution of functional dopamine D2 and D3 receptor variants to motor and non-motor symptoms of early onset Parkinson's disease.

DRD2 DRD3

6.19e-06287233039854
Pubmed

Latent-Profile Analysis Reveals Behavioral and Brain Correlates of Dopamine-Cognition Associations.

DRD2 DRD3

6.19e-06287229028935
Pubmed

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice.

DRD2 DRD3

6.19e-06287211864730
Pubmed

A preliminary study of dopamine D2/3 receptor availability and social status in healthy and cocaine dependent humans imaged with [(11)C](+)PHNO.

DRD2 DRD3

6.19e-06287226164205
Pubmed

Dopamine D2/D3 receptor stimulation fails to promote dopaminergic neurogenesis of murine and human midbrain-derived neural precursor cells in vitro.

DRD2 DRD3

6.19e-06287217784836
Pubmed

Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders.

DRD2 DRD3

6.19e-06287211857579
Pubmed

Exploring regulation and function of dopamine D3 receptors in alcohol use disorder. A PET [11C]-(+)-PHNO study.

DRD2 DRD3

6.19e-06287234349232
Pubmed

Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surface.

DRD2 DRD3

6.19e-06287222291025
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

6.19e-06287216847056
Pubmed

Relationship of frontal D(2/3) binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients.

DRD2 DRD3

6.19e-06287222338593
Pubmed

[¹¹C]-(+)-PHNO PET imaging of dopamine D(2/3) receptors in Parkinson's disease with impulse control disorders.

DRD2 DRD3

6.19e-06287225641350
Pubmed

Postnatal ontogeny of dopamine D3 receptors in the mouse brain: autoradiographic evidence for a transient cortical expression.

DRD2 DRD3

6.19e-0628728836575
Pubmed

A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities.

DRD2 DRD3

6.19e-06287239300138
Pubmed

Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors.

DRD2 DRD3

6.19e-06287219217026
Pubmed

Early expression of D3 dopamine receptors in murine embryonic development.

DRD2 DRD3

6.19e-0628728601467
Pubmed

Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum.

DRD2 DRD3

1.85e-05387218644790
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN9A

1.85e-05387219284629
Pubmed

Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects.

DRD2 DRD3

1.85e-05387220452395
Pubmed

Association of dopamine D(3) receptors with actin-binding protein 280 (ABP-280).

DRD2 DRD3

1.85e-05387211911837
Pubmed

Ependyma-expressed CCN1 restricts the size of the neural stem cell pool in the adult ventricular-subventricular zone.

CCN1 FOXJ1

1.85e-05387232009252
Pubmed

Association between dopamine receptor gene polymorphisms and effects of risperidone treatment: A systematic review and meta-analysis.

DRD2 DRD3

1.85e-05387230103286
Pubmed

Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography.

DRD2 DRD3

1.85e-05387212781734
Pubmed

DRD3, but not COMT or DRD2, genotype affects executive functions in healthy and first-episode psychosis adolescents.

DRD2 DRD3

1.85e-05387218351593
Pubmed

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors.

DRD2 DRD3

1.85e-0538727566118
Pubmed

Association study of dopamine receptor genes polymorphisms with the risk of schizophrenia in the Han Chinese population.

DRD2 DRD3

1.85e-05387227591410
Pubmed

Calmodulin mediates Ca2+ sensitivity of sodium channels.

SCN2A SCN5A

1.85e-05387215316014
Pubmed

Enhancement of dopamine-induced signaling responses in the forebrain of mice lacking dopamine D3 receptor.

DRD2 DRD3

1.85e-05387215016423
Pubmed

Prevalence of polymorphisms in the ANKK1, DRD2, DRD3 genes and metabolic syndrome in refractory schizophrenia.

DRD2 DRD3

1.85e-05387229791666
Pubmed

Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors.

DRD2 DRD3

1.85e-0538729354330
Pubmed

The mRNA Expression Status of Dopamine Receptor D2, Dopamine Receptor D3 and DARPP-32 in T Lymphocytes of Patients with Early Psychosis.

DRD2 DRD3

1.85e-05387226561806
Cytoband19q13.42

ZNF765 ZNF845 NLRP9 ZNF813

9.79e-0512587419q13.42
Cytoband10q11.2

NPY4R ALOX5

3.18e-041487210q11.2
Cytoband19q13.41

ZNF320 ZNF28 ZNF888

4.51e-047887319q13.41
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF765 ZNF845 NLRP9 ZNF320 ZNF28 ZNF813 ZNF888 NLRP8

1.93e-031192878chr19q13
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN5A SCN9A

2.46e-0695731203
GeneFamilyDopamine receptors

DRD2 DRD3

9.71e-055572181
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR12 SBF2

9.99e-0415572903
GeneFamilyNLR family

NLRP9 NLRP8

2.80e-0325572666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP9 NLRP8

2.80e-0325572994
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_200

LHX1 EIF4G1 CHM ADCY8 EDNRA DMXL1

3.75e-05157846gudmap_developingGonad_P2_epididymis_200
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_200

INHBB EIF4G1 ASPM CHM EDNRA DMXL1

4.03e-05159846gudmap_developingGonad_e12.5_epididymis_200
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200

EIF4G1 ASPM CHM EDNRA

1.00e-0461844gudmap_developingGonad_e12.5_epididymis_k2_200
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

SMG1 GAPVD1 EIF4G1 ASPM PDE10A CHM DMXL1

1.10e-04275847gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#2_top-relative-expression-ranked_200

EIF4G1 CHM EDNRA DMXL1

1.28e-0465844gudmap_developingGonad_e12.5_ovary_k2_200
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000

LHX1 RNF150 CTNNAL1 CCN1 KIF26B TAF2 AQR

1.62e-04293847gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500

LHX1 SMG1 EIF4G1 ASPM PDE10A CHM EDNRA DMXL1

2.30e-04413848gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500

NOL4 RNF150 INHBB SCN2A AQR

2.52e-04142845gudmap_developingKidney_e13.5_podocyte cells_500_k1
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_200

ZNF845 ATR TRPC1 CCDC150 CCNB1IP1

2.60e-04143845gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_200
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000

SMG1 GAPVD1 EIF4G1 PDE10A CHM EDNRA

2.70e-04225846gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

JAK1 LHX1 SMG1 RGS7BP EIF4G1 ASPM STMN2 CHM ADCY8 EDNRA DMXL1

3.04e-047998411gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

SMG1 GAPVD1 EIF4G1 ASPM CHM EDNRA

3.04e-04230846gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500

LHX1 NOL4 RNF150 INHBB KIF26B SCN2A DKK2 AQR

3.06e-04431848gudmap_developingKidney_e13.5_podocyte cells_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

JAK1 SMG1 EIF4G1 ASPM ATP13A3 TAF2

3.11e-04231846gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

EIF4G1 ASPM CHM EDNRA DMXL1

3.24e-04150845gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100

EIF4G1 CHM EDNRA DMXL1

3.46e-0484844gudmap_developingGonad_e14.5_ epididymis_100
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

STXBP1 IL1RAPL2 KIF26B SCN2A SCN9A STMN2 CYP4X1

8.76e-08188877b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SAT1 KIF26B SCN9A ASPM MC5R TAFA4 ADCY8

1.01e-071928770003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX1 PTCHD1 STXBP1 KIF26B SCN2A STMN2

1.82e-061878761b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INHBB KIF26B TAFA4 ADCY8 DKK2 EDNRA

2.05e-061918769c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CTNNAL1 HRH1 ATP13A3 PDE10A RFC3 DKK2

2.12e-061928767e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SAT1 KIF26B SCN9A ASPM TAFA4 ADCY8

2.18e-06193876c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

CYRIA FBP1 SAT1 SBF2 ATP13A3 ALOX5

2.31e-0619587646ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM STMN2 ATP13A3 C12orf60 SLC12A7

3.70e-06119875c3f1223356e7f245a460ea5568a223e34e458dc1
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

CUL3 ZNF320 ZNF28 SAT1 ZNF888

1.18e-051518752810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOL4 PTCHD1 SCN2A STMN2 RFX6

1.51e-051598757747cef94c55144fddcd024a7495318357f1351b
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_large-bowel / Manually curated celltypes from each tissue

NOL4 STXBP1 STMN2 RFX6 HEATR3

1.86e-0516687513bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCellCD8+_Memory_T_cell-FLU-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

TRPC1 CCDC150 CCL20 CDC6 RFC3

2.21e-0517287545ac433dbb3796f69e886c04457b2971403050ee
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SAT1 STMN2 ATP13A3 GPR45 DKK2

2.47e-0517687577516048aefbe1f48e825052756df0c310c1c486
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SAT1 STMN2 ATP13A3 GPR45 DKK2

2.47e-0517687596779273b94345250cf53ba671203345b43d9e00
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

ZNF845 GAPVD1 ZNF320 XPO6 CCDC150

2.60e-05178875536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF150 TRPC1 SCN5A ADCY8 EDNRA

2.67e-05179875bfc226bcf0b93525992344f968268a261d86fcbf
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF765 ZNF28 CCNB1IP1 RFC3 DMXL1

2.67e-051798755be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF150 TRPC1 SCN5A ADCY8 EDNRA

2.67e-0517987536ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STMN2 ATP13A3 C12orf60 SLC12A7 DKK2

2.75e-05180875baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STMN2 ATP13A3 C12orf60 SLC12A7 DKK2

2.75e-051808752d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STMN2 ATP13A3 C12orf60 SLC12A7 DKK2

2.75e-051808750f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Hippocampus / BrainAtlas - Mouse McCarroll V32

FBP1 SPINK2 MC5R TAFA4

2.81e-0589874b66575739cb5b89234bbb8a3ea2f244e0bd19cff
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FBP1 SPINK2 MC5R TAFA4

2.81e-058987426f01e8530b313dd5e95ea6c20fa362e34b9ed24
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 CCN1 ATP13A3 CHM ATP6V0A2

2.82e-0518187541969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 CCN1 ATP13A3 CHM ATP6V0A2

2.82e-051818753f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBP1 SCN2A SCN5A SCN9A STMN2

2.82e-051818757f99002a6411117cc2361334c7c9228e20c574b4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

2.97e-0518387504d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ADCY8 DKK2 MS4A10

2.97e-051838757961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCellwk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOL4 DRD2 INHBB STMN2 RFX6

3.05e-051848759e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX1 STXBP1 RGS7BP SCN2A STMN2

3.05e-051848757d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SAT1 KIF26B ASPM TAFA4 ADCY8

3.21e-051868756379609b7ace80683f5754b16aa77f11b43766ae
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

3.30e-05187875d413fb4b1531b297af5012a392b88128510c2de8
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STMN2 HRH1 ATP13A3 SLC12A7 DKK2

3.30e-051878757170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

CTNNAL1 HRH1 PDE10A RFC3 DKK2

3.38e-05188875eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHX1 RNF150 SAT1 IL1RAPL2 SCN2A

3.38e-05188875bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

3.38e-051888758de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LHX1 RNF150 SAT1 IL1RAPL2 SCN2A

3.47e-05189875977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INHBB KIF26B ADCY8 DKK2 EDNRA

3.47e-0518987506c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

CTNNAL1 SPINK2 ASPM CDC6 RFC3

3.47e-05189875946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF150 CYRIA SCN9A HRH1 ALOX5

3.47e-051898752586f4088721c5debec86c2b211b739fd33713eb
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CTNNAL1 HRH1 PDE10A RFC3 DKK2

3.56e-0519087507b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

3.56e-05190875305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SAT1 KIF26B ASPM TAFA4 ADCY8

3.56e-051908758c9c230a509afaeee50644153974a5642b01a2b8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

3.56e-051908750acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ASPM TAFA4 ADCY8

3.56e-05190875e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

STXBP1 CCN1 ASPM STMN2 HEATR3

3.56e-0519087539fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LHX1 RNF150 SAT1 IL1RAPL2 SCN2A

3.56e-05190875e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INHBB KIF26B ADCY8 DKK2 EDNRA

3.65e-05191875de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LHX1 PTCHD1 SCN2A STMN2 CYP4X1

3.65e-051918755d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LHX1 PTCHD1 SCN2A STMN2 CYP4X1

3.65e-0519187573dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B SCN9A ADCY8 DKK2 EDNRA

3.74e-05192875dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INHBB KIF26B ADCY8 DKK2 EDNRA

3.83e-051938752c15186d15545804cc262da9137ab825609d4b2c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ZNF845 ATR N4BP2 SBF2 AQR

3.83e-05193875abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 RGS7BP SBF2 SCN9A HRH1

3.83e-05193875aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 RGS7BP SBF2 SCN9A HRH1

3.83e-05193875c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBP1 SCN2A SCN5A SCN9A STMN2

3.83e-051938758851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

CYRIA SAT1 XPO6 SBF2 HEATR3

3.83e-05193875936ca95995599356b794fba32bfd82d8de339365
ToppCellCOPD-Myeloid|COPD / Disease state, Lineage and Cell class

CYRIA FBP1 SAT1 SBF2 ALOX5

3.83e-05193875f58552e286aa27e592497ad78776f58f8ee09841
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-Cortical_hem|1_mon / Sample Type, Dataset, Time_group, and Cell type.

SAT1 CCN1 CALU EDNRA FOXJ1

3.93e-051948756f32422e1c079a2fbf0ab568e6cb8365fd627d9a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBP1 SCN2A SCN5A SCN9A STMN2

3.93e-0519487515224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CTNNAL1 SAT1 CCN1 ATP13A3 DKK2

3.93e-05194875582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF26B ASPM CCDC150 CDC6 RFC3

3.93e-05194875590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CTNNAL1 SAT1 CCN1 ATP13A3 DKK2

3.93e-05194875bda89111386398a072b70e8153b2a762298a047a
ToppCellIPF-Myeloid|IPF / Disease state, Lineage and Cell class

CYRIA FBP1 SAT1 SBF2 ALOX5

4.02e-05195875fdeb958aeaa00f3fc25c4e59efbbc6f4a572c9ce
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

CYRIA SAT1 SBF2 ATP13A3 ALOX5

4.12e-051968754929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBP1 SAT1 ATP13A3 CCL20 ALOX5

4.12e-05196875a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCellSevere|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 CALU EIF4G1 ASPM CDC6

4.22e-05197875df3f58b58f82c42c65b0a09c054b669b34502037
ToppCellHealthy-T/NK_proliferative|World / disease group, cell group and cell class

CCN1 ASPM CCDC150 CDC6 RFC3

4.22e-05197875e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBP1 SAT1 ATP13A3 CCL20 ALOX5

4.33e-05198875dc59442e6a5127d3071a036c206732a21e456a17
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

CYRIA FBP1 SAT1 SBF2 ALOX5

4.33e-0519887533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-11|World / Primary Cells by Cluster

CTNNAL1 CCN1 ASPM CDC6 RFC3

4.33e-05198875672c6faeed54e1397e12c0aac1a5cbd19c684f06
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RNF150 DRD2 SAT1 CYP4X1 CCL20

4.43e-05199875527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYRIA FBP1 SAT1 ATP13A3 CCL20

4.43e-05199875880ba91ccecc6633f6daba7822d9200548a8632f
ToppCellmedial-Endothelial-Artery|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTNNAL1 INHBB HRH1 PDE10A DKK2

4.43e-05199875341c0be18bec66f4cc8bda232dce54edb34b9cda
ToppCelldistal-Endothelial-Bronchial_Vessel_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTNNAL1 CCN1 HRH1 RFC3 DKK2

4.43e-05199875bd9090c13a38a35d50f676fdf11b68eec1340bd3
ToppCell(06)_OLFM4+|World / shred by cell type by condition

SAT1 PDE10A SLC12A7 TRIM38 ALOX5

4.43e-05199875c773b9180dbfec9c19d4098dd43332e6f6050372
ToppCellmedial-2-Endothelial-Artery|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTNNAL1 INHBB HRH1 PDE10A DKK2

4.43e-0519987553c17c0493f82351a039bc64def191311e0f4951
ToppCellmedial-Endothelial-Artery-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTNNAL1 INHBB HRH1 PDE10A DKK2

4.43e-05199875c455f5a2802f2ec6f0e24266de1aaf3203ca8c78
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RNF150 CYRIA SCN9A HRH1 ALOX5

4.54e-05200875179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CTNNAL1 CCN1 HRH1 ATP13A3 DKK2

4.54e-05200875c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

KIF26B SCN9A ASPM TAFA4 ADCY8

4.54e-052008751276bfa911fddada4235e12e3081baa53164574b
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

SAT1 KIF26B SCN9A TAFA4 ADCY8

4.54e-05200875c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellSevere-Developping_Plasmablast|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 CALU EIF4G1 ASPM CDC6

4.54e-052008756d0cd00e52568d23597cc2a4059bd967d7d2dab5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

NOL4 CYRIA STXBP1 SCN2A STMN2

4.54e-0520087544bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CTNNAL1 CCN1 HRH1 ATP13A3 DKK2

4.54e-052008758a2c6c53a39fab86750526083f7254b7413b29af
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal|6m / Sample Type, Dataset, Time_group, and Cell type.

NOL4 CYRIA STXBP1 SCN2A STMN2

4.54e-05200875cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

NOL4 CYRIA STXBP1 SCN2A STMN2

4.54e-052008756f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells|1m / Sample Type, Dataset, Time_group, and Cell type.

CTNNAL1 ASPM TAFA4 CDC6 RFC3

4.54e-0520087513636463e44a99cd886926340bfb35880f95cca6
ToppCellSevere-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 CALU EIF4G1 ASPM CDC6

4.54e-0520087580639e0d2ddaae36ac7634a4f03e8809af7316e3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells-Neuroepithelial_cell|1m / Sample Type, Dataset, Time_group, and Cell type.

CTNNAL1 ASPM TAFA4 CDC6 RFC3

4.54e-052008752a3874634cc4357a64ef9fd4a6bbdfd84236ebac
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SAT1 KIF26B SCN9A TAFA4 ADCY8

4.54e-05200875117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

SAT1 KIF26B SCN9A TAFA4 ADCY8

4.54e-05200875d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DRD3 SPINK2 ASPM CDC6

1.09e-041268746072996987f7b05949adb86c9433e3302c4441d2
ToppCell368C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AADACL2 SCN5A RFC3 ARMH3

2.08e-04149874f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell368C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AADACL2 SCN5A RFC3 ARMH3

2.08e-041498749286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SCN2A PDE10A RFC3 DKK2

2.19e-041518743b4c57bad61e17a573e6f8dc6b917fba5fd56c43
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LHX1 SCN2A STMN2 DKK2

2.30e-0415387479c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ASXL1 INHBB STMN2 ARMH3

2.36e-04154874e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AXDND1 IFT172 CCL20 DKK2

2.73e-041608746005948e400e781cdb876ba350b3ec8991e3945f
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPINK2 TRPC1 SCN5A FOXJ1

2.79e-04161874aee74a2e7a8acd2950341963f1c04b59c7862183
Drugisofloxythepin

DRD2 DRD3 HRH1

1.74e-067853CID000115193
DrugCTK4D3724

DRD2 DRD3 HRH1

4.15e-069853CID000128010
DrugAC1OCEMN

DRD2 DRD3 HRH1

4.15e-069853CID006917765
Drugtegafur/uracil

NLRP9 CCL20 ATP6V0A2 NLRP8

6.82e-0633854CID000104747
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A

CUL3 STXBP1 RAB3GAP2 ARMH3 HEATR3 DMXL1 ATP6V0A2

8.24e-061948571264_DN
DrugChlorprothixene

DRD2 DRD3 HRH1

1.08e-0512853DB01239
DrugSulpiride

DRD2 DRD3

1.38e-052852DB00391
DrugN-n-propyl-N-phenylethyl-4(3-hydroxyphenyl)ethylamine hydrochloride

DRD2 DRD3

1.38e-052852ctd:C016868
DrugRanolazine

SCN5A SCN9A

1.38e-052852DB00243
Drug5-methoxy-1-methyl-2-(n-propylamino)tetralin

DRD2 DRD3

1.38e-052852ctd:C051171
DrugCGS 15855A

DRD2 DRD3

1.38e-052852ctd:C051347
Drug(5,6-dimethoxyindan-2-yl)dipropylamine

DRD2 DRD3

1.38e-052852ctd:C086335
DrugDomperidone

DRD2 DRD3

1.38e-052852DB01184
DrugUH 232

DRD2 DRD3

1.38e-052852ctd:C045971
Drug4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrzolo(3,4-g)quinoline

DRD2 DRD3

1.38e-052852ctd:C416545
Drug3-(3-cyanophenyl)-N-n-propylpiperidine

DRD2 DRD3

1.38e-052852ctd:C094012
Drugiodosulpride

DRD2 DRD3

1.38e-052852ctd:C045105
Drugfluoroclebopride

DRD2 DRD3

1.38e-052852ctd:C083673
DrugGR 218231

DRD2 DRD3

1.38e-052852ctd:C408390
Drugefletirizine

HRH1 ALOX5

1.38e-052852ctd:C121361
DrugN-(4-(2-(4-(3-cyano-5-trifluoromethylphenyl)piperazin-1-yl)ethyl)cyclohexyl)-3-pyridinesulfonic amide

DRD2 DRD3

1.38e-052852ctd:C539157
DrugPiribedil

DRD2 DRD3

1.38e-052852ctd:D010891
DrugAC1L31N6

DRD2 DRD3

1.38e-052852CID000132830
Drugdiphenidol

DRD2 DRD3 HRH1

1.40e-0513853CID000003055
DrugRisperidone

DRD2 DRD3 HRH1

1.77e-0514853DB00734
DrugDB08666

SCN2A SCN5A EIF4G1 HRH1 CCL20

2.21e-0590855CID011840988
DrugA 86929

DRD2 DRD3 EDNRA

2.21e-0515853ctd:C095427
DrugAC1L2AAS

DRD2 DRD3 ADCY8

2.21e-0515853CID000068714
Drugfluphenazine

DRD2 DRD3 SCN9A HRH1 ADCY8

2.72e-0594855CID000003372
DrugPaliperidone

DRD2 DRD3 HRH1

3.29e-0517853DB01267
DrugZonisamide

SCN2A SCN5A SCN9A

3.29e-0517853DB00909
DrugPGW5 compound

DRD2 DRD3 HRH1

3.29e-0517853ctd:C000593032
DrugAC1Q7BEJ

DRD2 DRD3 HRH1 ADCY8

3.65e-0550854CID000001224
Drugmoricizine

SCN5A SCN9A HRH1

3.93e-0518853CID000034632
Drug(1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate)

DRD2 DRD3

4.12e-053852ctd:C461261
DrugDP-6OH-3CA

DRD2 DRD3

4.12e-053852CID000086146
DrugNeuriplege

DRD2 DRD3

4.12e-053852CID000065750
Drug7-(N,N-dipropylamino)-5,6,7,8-tetrahydronaphtho(2,3-b)dihydro-2,3-furan

DRD2 DRD3

4.12e-053852ctd:C090812
Drug7-hydroxy-2-N,N-dipropylaminotetralin

DRD2 DRD3

4.12e-053852ctd:C031349
Drug3-N-methylspiperone

DRD2 DRD3

4.12e-053852ctd:C039167
Drugquinelorane

DRD2 DRD3

4.12e-053852ctd:C047726
DrugFLA908

DRD2 DRD3

4.12e-053852CID000129516
DrugSB-277011

DRD2 DRD3

4.12e-053852CID005311096
DrugDCHAPS

DRD2 DRD3

4.12e-053852CID000129392
Drugnafadotride

DRD2 DRD3

4.12e-053852ctd:C097285
DrugBP 897

DRD2 DRD3

4.12e-053852ctd:C120565
Drugiodoethylspiperone

DRD2 DRD3

4.12e-053852CID000131222
DrugRo 41-9067

DRD2 DRD3 ADCY8

4.66e-0519853CID000125800
DrugMethotrimeprazine

DRD2 DRD3 HRH1

4.66e-0519853DB01403
DrugRP 62203

DRD2 DRD3 HRH1

4.66e-0519853CID000060785
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A

CYRIA STXBP1 ATR CALU CCL20 DMXL1

7.02e-051868561612_UP
DrugNSC186061

DRD2 DRD3 HRH1 ALOX5 ADCY8

8.09e-05118855CID000004163
Drugmetopimazine

DRD2 HRH1

8.22e-054852CID000026388
DrugLidocaine

SCN5A SCN9A

8.22e-054852DB00281
Drugclofluperol

DRD2 DRD3

8.22e-054852CID000025293
DrugPimozide

DRD2 DRD3

8.22e-054852DB01100
DrugNCQ-469

DRD2 DRD3

8.22e-054852CID000127915
Drugspectramide

DRD2 DRD3

8.22e-054852CID000130377
DrugAmisulpride

DRD2 DRD3

8.22e-054852DB06288
Drugsarizotan

DRD2 DRD3

8.22e-054852ctd:C443959
DrugCinnarizine

DRD2 HRH1

8.22e-054852ctd:D002936
Drug3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol

DRD2 DRD3

8.22e-054852ctd:C062458
DrugSKF83959

DRD2 DRD3

8.22e-054852CID000133538
Drugethacizine

SCN9A HRH1

8.22e-054852CID000107841
DrugCAS 66104-23-2

DRD2 DRD3 HRH1 ADCY8

9.11e-0563854CID000004745
DrugTL-99

DRD2 DRD3 ADCY8

9.60e-0524853CID000122132
DrugAnabasine [494-52-0]; Up 200; 24.6uM; HL60; HT_HG-U133A

CYRIA SPAM1 FBP1 IL1RAPL2 TRPC1 ALOX5

9.64e-051978562512_UP
DrugS-(-)-Lisuride

DRD2 DRD3 HRH1 ADCY8

1.03e-0465854CID000003938
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A

LHX1 DRD2 TRPC1 PDE10A GPR45 EDNRA

1.05e-042008564605_UP
DrugOlanzapine

DRD2 DRD3 HRH1

1.09e-0425853DB00334
DrugZiprasidone

DRD2 DRD3 HRH1

1.09e-0425853DB00246
DrugAripiprazole

DRD2 DRD3 HRH1

1.09e-0425853DB01238
Drughydroxamates

DRD2 DRD3 HRH1

1.09e-0425853CID000033630
Druglamotrigine

DRD2 SCN2A HRH1

1.09e-0425853ctd:C047781
DrugN-n-propylnorapomorphine

DRD2 DRD3 ADCY8

1.09e-0425853CID000030137
DrugClozapine

DRD2 DRD3 HRH1

1.23e-0426853DB00363
DrugQuetiapine

DRD2 DRD3 HRH1

1.23e-0426853DB01224
DrugT15550

DRD2 DRD3 HRH1

1.23e-0426853CID000005454
Drugcyamemazine

DRD2 DRD3 HRH1

1.23e-0426853CID000062865
Drugtyramine

DRD2 DRD3 HRH1 ADCY8 EDNRA

1.28e-04130855CID000005610
DrugGBR 12909

DRD2 DRD3 SCN9A HRH1

1.30e-0469854CID000003455
DrugHaloperidol

DRD2 DRD3

1.37e-045852DB00502
DrugRemoxipride

DRD2 DRD3

1.37e-045852DB00409
Drugtilozepine

DRD2 DRD3

1.37e-045852CID000172286
DrugSKF 77434

DRD2 DRD3

1.37e-045852CID000001241
DrugLevodopa

DRD2 DRD3

1.37e-045852DB01235
Drugmoperone

DRD2 DRD3

1.37e-045852CID000004249
Drugdazopride

DRD2 DRD3

1.37e-045852CID000054801
Drughaloperidol hemisuccinate

DRD2 DRD3

1.37e-045852CID000088143
Drugazapride

DRD2 DRD3

1.37e-045852CID003036441
Drug2-di-n-propylaminoindan

DRD2 DRD3

1.37e-045852CID000130402
Drugmezilamine

DRD2 DRD3

1.37e-045852CID000068678
DrugNO 756

DRD2 DRD3

1.37e-045852CID000129967
DrugSKF85174

DRD2 DRD3

1.37e-045852CID000132435
Drugpipotiazine

DRD2 DRD3

1.37e-045852CID000062867
Drug3-iodobenzamide

DRD2 DRD3

1.37e-045852CID000202425
Drugdeclopramide

DRD2 DRD3

1.37e-045852CID000070177
Drugtefludazine

DRD2 DRD3

1.37e-045852CID000071240
Drugrotigotine

DRD2 DRD3

1.37e-045852ctd:C047508
Drugpiquindone

DRD2 DRD3

1.37e-045852CID000121903
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN5A SCN9A

2.73e-0610853DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN5A SCN9A

2.73e-0610853DOID:0080422 (implicated_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

DRD2 DRD3 TRPC1

4.98e-0612853DOID:0050742 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN5A SCN9A

4.98e-0612853DOID:0060170 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

STXBP1 SCN2A SCN9A

6.46e-0613853C0751122
DiseaseDisruptive, Impulse Control, and Conduct Disorders

DRD2 DRD3

2.46e-053852C0021122
DiseaseIntermittent Explosive Disorder

DRD2 DRD3

2.46e-053852C0021776
Diseasefacial height measurement

CYRIA ZNF28 KIAA0825 RAB3GAP2 SCN5A

5.79e-05142855EFO_0007856
Diseaseheroin dependence (biomarker_via_orthology)

DRD2 DRD3

8.15e-055852DOID:9976 (biomarker_via_orthology)
Diseaseresponse to selective serotonin reuptake inhibitor

PTCHD1 MTMR12 KIF26B STMN2

9.45e-0582854EFO_0005658
DiseaseHyperkinesia, Generalized

DRD2 DRD3 ADCY8

1.08e-0432853C0751217
DiseaseHyperkinesia

DRD2 DRD3 ADCY8

1.08e-0432853C3887506
Diseaseepilepsy (implicated_via_orthology)

SCN2A SBF2 SCN5A SCN9A SLC12A7

1.11e-04163855DOID:1826 (implicated_via_orthology)
DiseaseAntihypertensive use measurement

KIAA0825 SBF2 PDE10A RMC1 ADCY8 EDNRA

1.20e-04265856EFO_0009927
Diseaseatrioventricular septal defect (implicated_via_orthology)

CCN1 IFT172

1.71e-047852DOID:0050651 (implicated_via_orthology)
DiseaseEarly Childhood Epilepsy, Myoclonic

STXBP1 SCN9A

2.27e-048852C0393695
DiseaseIdiopathic Myoclonic Epilepsy

STXBP1 SCN9A

2.27e-048852C0338478
DiseaseSymptomatic Myoclonic Epilepsy

STXBP1 SCN9A

2.27e-048852C0338479
DiseaseMyoclonic Encephalopathy

STXBP1 SCN9A

2.27e-048852C0438414
DiseaseBenign Infantile Myoclonic Epilepsy

STXBP1 SCN9A

2.27e-048852C0751120
DiseaseMyoclonic Absence Epilepsy

STXBP1 SCN9A

2.27e-048852C0393703
DiseasePruritus

SCN9A HRH1

2.27e-048852C0033774
Diseaseneuroticism measurement, cognitive function measurement

ASXL1 DRD2 KIAA0825 CALU N4BP2 SCN2A RMC1 ADCY8

2.30e-04566858EFO_0007660, EFO_0008354
DiseaseRecurrent depression

DRD2 DRD3

2.91e-049852C0221480
DiseaseMyoclonic Epilepsy

STXBP1 SCN9A

2.91e-049852C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN2A SCN9A

2.91e-049852C3502809
Diseasemyelodysplastic syndrome

TAF2 TAFA4

3.64e-0410852EFO_0000198
DiseaseEpilepsy, Myoclonic, Infantile

STXBP1 SCN9A

3.64e-0410852C0917800
DiseaseDelirium

DRD2 DRD3

3.64e-0410852C0011206
DiseaseMyoclonic Astatic Epilepsy

STXBP1 SCN9A

4.44e-0411852C0393702
DiseaseLenticulostriate Disorders

DRD2 DRD3

5.31e-0412852C0750951
DiseaseExtrapyramidal Disorders

DRD2 DRD3

5.31e-0412852C0015371
DiseaseBasal Ganglia Diseases

DRD2 DRD3

5.31e-0412852C0004782
DiseaseWithdrawal Symptoms

DRD2 HRH1 ADCY8

6.35e-0458853C0087169
DiseaseDrug Withdrawal Symptoms

DRD2 HRH1 ADCY8

6.35e-0458853C0086189
DiseaseSubstance Withdrawal Syndrome

DRD2 HRH1 ADCY8

6.35e-0458853C0038587
DiseaseDyskinesia, Drug-Induced

DRD2 DRD3

8.40e-0415852C0013386
DiseaseDyskinesia, Medication-Induced

DRD2 DRD3

8.40e-0415852C0751088
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

STXBP1 SCN2A

9.59e-0416852C0393706
DiseaseAlcoholic Intoxication, Chronic

DRD2 DRD3 SAT1 PDE10A DKK2

1.08e-03268855C0001973
DiseaseParkinson's disease (implicated_via_orthology)

DRD2 DRD3 EIF4G1 ATP13A3

1.12e-03157854DOID:14330 (implicated_via_orthology)
Diseaseportal hypertension (implicated_via_orthology)

ALOX5 EDNRA

1.36e-0319852DOID:10762 (implicated_via_orthology)
DiseaseChronic myeloproliferative disorder

ATR CDC6

1.36e-0319852C1292778
DiseaseMood Disorders

DRD2 DRD3 SAT1 ADCY8

1.43e-03168854C0525045
DiseaseInfiltrating duct carcinoma of female breast

SMG1 ATR

1.66e-0321852C3165106
Diseasecigarettes per day measurement

ASXL1 DRD2 STXBP1 SCN2A RMC1 ADCY8

1.68e-03438856EFO_0006525
DiseaseSeckel syndrome

ATR CDC6

1.82e-0322852C0265202
Diseaseanxiety disorder (implicated_via_orthology)

SCN2A SCN9A

1.82e-0322852DOID:2030 (implicated_via_orthology)
Diseasesmoking status measurement

CUL3 NOL4 RNF150 GAPVD1 DRD2 SPINK2 RAB3GAP2 SCN2A RMC1 ADCY8

1.83e-0311608510EFO_0006527
Diseaseheel bone mineral density, urate measurement

NPY4R2 NPY4R PDE10A DKK2

1.92e-03182854EFO_0004531, EFO_0009270
DiseaseEtat Marbre

DRD2 DRD3

1.99e-0323852C0266487
DiseaseWest Syndrome

STXBP1 SCN2A

2.17e-0324852C0037769
Diseasenephrotic syndrome (implicated_via_orthology)

GAPVD1 ALOX5

2.17e-0324852DOID:1184 (implicated_via_orthology)
Diseasetraumatic brain injury (biomarker_via_orthology)

DRD2 PDE10A

2.17e-0324852DOID:0081292 (biomarker_via_orthology)
DiseaseNeurodevelopmental Disorders

CUL3 STXBP1 SCN2A

2.48e-0393853C1535926
Diseasesmoking cessation

CUL3 ASXL1 DRD2 STXBP1 SCN2A

2.51e-03325855EFO_0004319
DiseaseBipolar Disorder

DRD2 DRD3 SAT1 SCN2A PDE10A ADCY8

2.58e-03477856C0005586

Protein segments in the cluster

PeptideGeneStartEntry
CCVEMGLSMIKTIRY

ADCY8

481

P40145
KTCTFTAMCFENMRI

AADACL2

41

Q6P093
EMLVKSQFVACMATC

ATP13A3

531

Q9H7F0
ETFSKNVMMIQSCKC

CCN1

341

O00622
CMKNLMESLDSLLCA

ARMH3

136

Q5T2E6
CCCYQSKSLMTSVPM

EDNRA

386

P25101
MDLRQFLMCLSLCTA

CALU

1

O43852
SSKAYLMSICCMVNE

AQR

86

O60306
SCDMCELARNSVLMS

AMPD2

791

Q01433
MAALMRSKDSSCCLL

DKK2

1

Q9UBU2
SLCKSIMMYACTKNV

DMXL1

541

Q9Y485
MAYMCTSQQTCKVPL

ASPM

401

Q8IZT6
SISLQCACSLKAMIM

ASXL1

1501

Q8IXJ9
ELCSSTMTCMKGTYL

CHM

491

P24386
CLEMYTTEMLKSICL

RGS7BP

131

Q6MZT1
VDTLIMMYKTHCQCI

RFX6

261

Q8HWS3
SCKELADLMTRCMNY

JAK1

816

P23458
ICCLHTMLSLLSKMK

RAB3GAP2

791

Q9H2M9
DCLSTMTSVCKVMLE

CYRIA

221

Q9H0Q0
ALMMALVVLSCKSSC

IFNA14

6

P01570
ICMCLKSIMGDQTSI

KIAA0825

1051

Q8IV33
ETLCKMSAFIQCMSV

NPY4R

111

P50391
DLCCLISSLVQLMMD

MTMR12

396

Q9C0I1
IIRMMNCTLQDCSSL

SBF2

611

Q86WG5
TSNIFAIMNCDKMCV

NLRP8

101

Q86W28
TSICCQAMASMLRKN

NLRP8

966

Q86W28
CCIPTKLSTMSMLYF

INHBB

371

P09529
CKAHLMMITCFDITS

KIF26B

2091

Q2KJY2
CILRMCSTIMNLLSL

GAPVD1

1396

Q14C86
IGLMMTACDLCSVTK

PDE10A

656

Q9Y233
KMLCLMTNLISLFCV

MS4A10

121

Q96PG2
LNCFTCMMCNKQLST

LHX1

86

P48742
MLCAYMCILNTVRKN

GPR45

211

Q9Y5Y3
MSTYANECTLCMKIR

SPINK2

56

P20155
SCSKTMILNFCSYMQ

IFT172

516

Q9UG01
LVMNMLKSSFATCVL

FBP1

81

P09467
EMQLTSAKCLTYMCR

ARMC8

251

Q8IUR7
LASKIFTCCSIMMKH

ATR

1506

Q13535
ISQCMTPDQLMTLCK

HEATR3

531

Q7Z4Q2
KKCSELSCMLQTVTM

CCDC150

351

Q8NCX0
LEKCTMMLLTASKTC

CTNNAL1

231

Q9UBT7
YLSSCCKGMVTAMAL

AXDND1

761

Q5T1B0
KTMCECMSSYLREQG

CUL3

311

Q13618
LGEMSYTTMCIKETC

CYP4X1

361

Q8N118
YATLICMAMQASKAT

FOXJ1

126

Q92949
FKTIMLNCMSLRTAQ

CDC6

226

Q99741
ANMCRCLMALKVPTT

EIF4G1

816

Q04637
MICISVVASMCSLLA

MC5R

121

P33032
IMELLIMVYACKTSC

PRPSAP2

86

O60256
RSMKSCLLLDNYMET

SPAM1

346

P38567
RMCYLTIKEMSCIAE

COPG1

86

Q9Y678
MMCTASILNLCAISI

DRD2

116

P14416
MSLPNSSCLLEDKMC

HRH1

1

P35367
IVAMCCTCTMLTAIS

SLC12A7

156

Q9Y666
VMMCTASILNLCAIS

DRD3

111

P35462
TMEKYMSTCRLILCC

RFC3

151

P40938
MAMSLIQACCSLALS

RNF150

1

Q9ULK6
LAYVLMVCCKLMSAS

TAFA4

21

Q96LR4
MEEATCSICLSLMTN

TRIM38

11

O00635
MVQRAMKDLTYASLC

ALOX5

436

P09917
TMAILCCSMQDCVRS

PTCHD1

281

Q96NR3
MSACFCLAKIANSMV

TAF2

696

Q6P1X5
CVLRNSTYCMKVSMS

IL1RAPL2

116

Q9NP60
MEMLSSCAISFCKSV

SMG1

1501

Q96Q15
SLFNMLIMCTILTNC

SCN5A

131

Q14524
SLFSMLIMCTILTNC

SCN9A

126

Q15858
KNLSQVAMRCRCSSM

SAT1

111

P21673
LVVDQLSMRMLSSCC

STXBP1

31

P61764
LSMRMLSSCCKMTDI

STXBP1

36

P61764
LSSCCKMTDIMTEGI

STXBP1

41

P61764
VTRFLMSCSECQKRM

NOL4

151

O94818
MCCTKSLLLAALMSV

CCL20

1

P78556
MSLCEDMLLCNYRKC

CCNB1IP1

1

Q9NPC3
LCSKVAMAMCSVVQK

C12orf60

86

Q5U649
CALERLMLMYCCLTS

NLRP9

771

Q7RTR0
LMLMYCCLTSVSCDS

NLRP9

776

Q7RTR0
YRNLVSLDISSKCMM

ZNF845

41

Q96IR2
CCLVHRYLTSMRQKM

TRPC1

736

P48995
CLSLDKVIMEMSTCE

UHRF1BP1L

81

A0JNW5
YRNLVSLDISSKCMM

ZNF320

41

A2RRD8
CKMVILSVCSQMLSE

RMC1

386

Q96DM3
MDKCVCLLTAFSERM

SPATA20

666

Q8TB22
MCTILTNCVFMTMSN

SCN2A

136

Q99250
ETLCKMSAFIQCMSV

NPY4R2

111

P0DQD5
YRNLVSLDISSKCMM

ZNF813

41

Q6ZN06
YRNLVSLDISSKCMM

ZNF888

41

P0CJ79
YRNLVSLDISSKCMM

ZNF28

41

P17035
YRNLVSLDISSKCMM

ZNF765

41

Q7L2R6
KMKELSMLSLICSCF

STMN2

11

Q93045
LAMSCINELMSKNCV

XPO6

311

Q96QU8
MLNMCSFDVTNKCLI

ATP6V0A2

311

Q9Y487
MLLSEMTCESQTCLS

N4BP2

951

Q86UW6