Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF18A DNAH3 ABCC4 TCP1 ABCB5 DCP2 TRPM2 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 CCT6A ARL8B SEPTIN14 CCT6B HFM1 ABCD2

2.59e-0683914420GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF18A DNAH3 ABCC4 TCP1 ABCB5 DCP2 TRPM2 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 CCT6A ARL8B SEPTIN14 CCT6B HFM1 ABCD2

2.64e-0684014420GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF18A DNAH3 ABCC4 TCP1 ABCB5 DCP2 TRPM2 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 CCT6A ARL8B SEPTIN14 CCT6B HFM1 ABCD2

2.64e-0684014420GO:0016818
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF18A DNAH3 ABCC4 TCP1 ABCB5 PEX1 SRP54 CHD8 DDX51 DNAH7 CCT6A CCT6B HFM1 ABCD2

3.86e-0644114414GO:0016887
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRT PTPRA PTPRE PTPRR

5.74e-06171444GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRT PTPRA PTPRE PTPRR

5.74e-06171444GO:0019198
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF18A DNAH3 ABCC4 TCP1 ABCB5 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 CCT6A ARL8B SEPTIN14 CCT6B HFM1 ABCD2

1.22e-0577514418GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

KIF18A DNAH3 ABCC4 WAPL TCP1 ABCB5 PEX1 SRP54 CHD8 DDX51 DNAH7 CCT6A CCT6B HFM1 ABCD2

3.85e-0561414415GO:0140657
GeneOntologyCellularComponentchaperonin-containing T-complex

TCP1 CCT6A CCT6B

5.07e-05111443GO:0005832
DomainChaprnin_Cpn60

TCP1 CCT6A CCT6B

3.35e-0591403IPR001844
DomainChaperonin_TCP-1_CS

TCP1 CCT6A CCT6B

3.35e-0591403IPR002194
Domain-

MPP1 DNAH3 ABCC4 ABCB5 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 PALS1 TRANK1 ARL8B SEPTIN14 HFM1 ABCD2

4.41e-05746140173.40.50.300
DomainTCP1_1

TCP1 CCT6A CCT6B

4.76e-05101403PS00750
DomainTCP1_2

TCP1 CCT6A CCT6B

4.76e-05101403PS00751
DomainTCP1_3

TCP1 CCT6A CCT6B

4.76e-05101403PS00995
DomainChaperone_TCP-1

TCP1 CCT6A CCT6B

4.76e-05101403IPR017998
DomainChap_CCT_zeta

CCT6A CCT6B

5.58e-0521402IPR012722
DomainTyr_Pase_rcpt_a/e-type

PTPRA PTPRE

5.58e-0521402IPR016336
DomainP-loop_NTPase

MPP1 KIF18A DNAH3 ABCC4 ABCB5 PEX1 SRP54 CHD8 DDX51 ARL8A DNAH7 MFN1 PALS1 TRANK1 ARL8B SEPTIN14 HFM1 ABCD2

6.50e-0584814018IPR027417
Domain-

TCP1 CCT6A CCT6B

6.51e-051114033.30.260.10
DomainTCP-1-like_intermed

TCP1 CCT6A CCT6B

6.51e-05111403IPR027410
DomainAAA

DNAH3 ABCC4 ABCB5 PEX1 SRP54 DNAH7 ABCD2

1.07e-041441407SM00382
DomainAAA+_ATPase

DNAH3 ABCC4 ABCB5 PEX1 SRP54 DNAH7 ABCD2

1.07e-041441407IPR003593
DomainGROEL-like_equatorial

TCP1 CCT6A CCT6B

1.41e-04141403IPR027413
Domain-

TCP1 CCT6A CCT6B

1.41e-041414031.10.560.10
DomainPTPc

PTPRT PTPRA PTPRE PTPRR

1.48e-04361404SM00194
DomainTF_GATA-2/3

GATA2 GATA3

1.67e-0431402IPR016374
DomainGroEL-like_apical_dom

TCP1 CCT6A CCT6B

1.76e-04151403IPR027409
DomainCpn60/TCP-1

TCP1 CCT6A CCT6B

1.76e-04151403IPR002423
DomainCpn60_TCP1

TCP1 CCT6A CCT6B

1.76e-04151403PF00118
Domain-

TCP1 CCT6A CCT6B

1.76e-041514033.50.7.10
DomainTYR_PHOSPHATASE_PTP

PTPRT PTPRA PTPRE PTPRR

2.03e-04391404PS50055
DomainPTPase_domain

PTPRT PTPRA PTPRE PTPRR

2.47e-04411404IPR000242
DomainY_phosphatase

PTPRT PTPRA PTPRE PTPRR

2.47e-04411404PF00102
DomainArgonaute_N

AGO1 AGO4

3.31e-0441402IPR032474
DomainArgonaute_Mid_dom

AGO1 AGO4

3.31e-0441402IPR032473
DomainArgoL2

AGO1 AGO4

3.31e-0441402IPR032472
DomainArgoN

AGO1 AGO4

3.31e-0441402PF16486
DomainArgoMid

AGO1 AGO4

3.31e-0441402PF16487
DomainArgoL2

AGO1 AGO4

3.31e-0441402PF16488
DomainRho_GTPase_activation_prot

BCR NF1 DLC1 ARHGAP31 ARHGAP29

5.24e-04881405IPR008936
DomainSAM

ANKS4B DLC1 SHANK2 SAMD11 TP73

5.24e-04881405SM00454
DomainDUF1785

AGO1 AGO4

5.50e-0451402SM01163
DomainSAM_DOMAIN

ANKS4B DLC1 SHANK2 SAMD11 TP73

7.43e-04951405PS50105
DomainSAM

ANKS4B DLC1 SHANK2 SAMD11 TP73

8.17e-04971405IPR001660
DomainArgoL1

AGO1 AGO4

8.20e-0461402PF08699
DomainArgoL1

AGO1 AGO4

8.20e-0461402IPR014811
DomainZnf_FYVE_PHD

TCF20 NSD1 JADE1 KDM2B ZFYVE26 DNMT3B

8.48e-041471406IPR011011
DomainPTPc_motif

PTPRT PTPRA PTPRE PTPRR

1.00e-03591404SM00404
DomainTyr_Pase_cat

PTPRT PTPRA PTPRE PTPRR

1.00e-03591404IPR003595
DomainABC_TM1F

ABCC4 ABCB5 ABCD2

1.18e-03281403PS50929
DomainABC1_TM_dom

ABCC4 ABCB5 ABCD2

1.18e-03281403IPR011527
DomainRhoGAP

BCR DLC1 ARHGAP31 ARHGAP29

1.20e-03621404SM00324
DomainRhoGAP

BCR DLC1 ARHGAP31 ARHGAP29

1.28e-03631404PF00620
DomainRhoGAP_dom

BCR DLC1 ARHGAP31 ARHGAP29

1.36e-03641404IPR000198
DomainRHOGAP

BCR DLC1 ARHGAP31 ARHGAP29

1.36e-03641404PS50238
Domain-

BCR DLC1 ARHGAP31 ARHGAP29

1.36e-036414041.10.555.10
DomainHMG_box_dom

SOX2 SH3GL2 SRY PROX1

1.44e-03651404IPR009071
DomainPIWI

AGO1 AGO4

1.52e-0381402PS50822
DomainPiwi

AGO1 AGO4

1.52e-0381402SM00950
DomainPiwi

AGO1 AGO4

1.52e-0381402PF02171
DomainPiwi

AGO1 AGO4

1.52e-0381402IPR003165
DomainChromodomain-like

ARID4A CHD8 CDYL2

1.74e-03321403IPR016197
DomainSAM/pointed

ANKS4B DLC1 SHANK2 SAMD11 TP73

1.89e-031171405IPR013761
DomainChromo/shadow_dom

ARID4A CHD8 CDYL2

1.91e-03331403IPR000953
DomainCHROMO

ARID4A CHD8 CDYL2

1.91e-03331403SM00298
DomainPAZ

AGO1 AGO4

1.94e-0391402PS50821
DomainPAZ

AGO1 AGO4

1.94e-0391402SM00949
DomainPAZ

AGO1 AGO4

1.94e-0391402PF02170
DomainPAZ_dom

AGO1 AGO4

1.94e-0391402IPR003100
DomainTyr_Pase_AS

PTPRT PTPRA PTPRE PTPRR

2.21e-03731404IPR016130
DomainLAM_G_DOMAIN

CNTNAP3B CNTNAP3 EGFLAM

2.87e-03381403PS50025
DomainLaminin_G_2

CNTNAP3B CNTNAP3 EGFLAM

3.33e-03401403PF02210
DomainZnF_GATA

GATA2 GATA3

3.51e-03121402SM00401
DomainABC_transporter_CS

ABCC4 ABCB5 ABCD2

3.82e-03421403IPR017871
DomainSH3_2

MPP1 SH3GL2 PALS1 SHANK2

3.99e-03861404PF07653
DomainSH3_2

MPP1 SH3GL2 PALS1 SHANK2

3.99e-03861404IPR011511
DomainTYR_PHOSPHATASE_1

PTPRT PTPRA PTPRE PTPRR

3.99e-03861404PS00383
DomainSAM_2

DLC1 SAMD11 TP73

4.09e-03431403PF07647
DomainTYR_PHOSPHATASE_dom

PTPRT PTPRA PTPRE PTPRR

4.16e-03871404IPR000387
DomainTYR_PHOSPHATASE_2

PTPRT PTPRA PTPRE PTPRR

4.16e-03871404PS50056
DomainLamG

CNTNAP3B CNTNAP3 EGFLAM

4.36e-03441403SM00282
DomainPHD

TCF20 NSD1 JADE1 KDM2B

4.51e-03891404SM00249
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH7

4.79e-03141402IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH7

4.79e-03141402IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH7

4.79e-03141402IPR013602
DomainDHC_N2

DNAH3 DNAH7

4.79e-03141402PF08393
DomainMT

DNAH3 DNAH7

4.79e-03141402PF12777
DomainAAA_8

DNAH3 DNAH7

4.79e-03141402PF12780
DomainZnf_PHD

TCF20 NSD1 JADE1 KDM2B

4.88e-03911404IPR001965
Domain-

PTPRT PTPRA PTPRE PTPRR

5.08e-039214043.90.190.10
DomainDHC_fam

DNAH3 DNAH7

5.49e-03151402IPR026983
Domain-

ARID4A ARID5A

5.49e-031514021.10.150.60
DomainBRIGHT

ARID4A ARID5A

5.49e-03151402SM00501
DomainARID_dom

ARID4A ARID5A

5.49e-03151402IPR001606
DomainARID

ARID4A ARID5A

5.49e-03151402PS51011
DomainDynein_heavy

DNAH3 DNAH7

5.49e-03151402PF03028
DomainZnf_GATA

GATA2 GATA3

5.49e-03151402IPR000679
DomainGATA

GATA2 GATA3

5.49e-03151402PF00320
DomainARID

ARID4A ARID5A

5.49e-03151402PF01388
DomainDynein_heavy_dom

DNAH3 DNAH7

5.49e-03151402IPR004273
DomainABC_tran

ABCC4 ABCB5 ABCD2

5.57e-03481403PF00005
DomainABC_TRANSPORTER_2

ABCC4 ABCB5 ABCD2

5.57e-03481403PS50893
DomainZF_PHD_2

TCF20 NSD1 JADE1 KDM2B

5.69e-03951404PS50016
DomainZF_PHD_1

TCF20 NSD1 JADE1 KDM2B

5.90e-03961404PS01359
DomainABC_TRANSPORTER_1

ABCC4 ABCB5 ABCD2

5.90e-03491403PS00211
DomainABC_transporter-like

ABCC4 ABCB5 ABCD2

6.25e-03501403IPR003439
DomainPost-SET_dom

NSD1 SETDB1

6.25e-03161402IPR003616
DomainGATA_ZN_FINGER_1

GATA2 GATA3

6.25e-03161402PS00344
PathwayREACTOME_FOLDING_OF_ACTIN_BY_CCT_TRIC

TCP1 CCT6A CCT6B

5.63e-05101123M27299
PathwayREACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS

TCP1 CCT6A CCT6B

5.63e-05101123MM15004
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 TCF20 SH3GL2 NSD1 CHD8 ARMCX4 BCR ZNF462 PALS1 KCNA1 NF1 AGO1 SHANK2 PABPC3 KCTD16 NGEF MTCL1 CDC73 PROX1

2.49e-089631461928671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WAPL TEX2 CHD8 JADE1 ANKRD50 BCR TRANK1 AGO4 SMG7 ARHGAP31 CCSER2 SENP6 KDM2B

4.06e-075291461314621295
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

SOX2 TCF20 NSD1 CHD8 ZFPM2 NGEF PCCB

4.14e-07109146733554859
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TRAPPC11 TCF20 DDX51 ARL8A CSMD2 DCAF12L2 AP3M1 DNAH7 NF1 KDM2B SYPL1 HFM1 MTCL1 FER1L5

5.55e-076381461431182584
Pubmed

Human transcription factor protein interaction networks.

SOX2 NUSAP1 TCF20 TCP1 ARID4A GATA2 GATA3 CHD8 SPAG9 ZFPM2 PDIA4 ZNF462 CCT6A SETDB1 PALS1 AGO1 SMG7 SAMD11 PABPC3 KDM2B PCCB

6.05e-0714291462135140242
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

WAPL TCF20 TCP1 FBL NSD1 CHD8 SPAG9 USP14 CCT6A PALS1 SMG7 KDM2B HDLBP

6.16e-075491461338280479
Pubmed

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis.

GATA2 GATA3 ZFPM2

7.20e-075146320705609
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GPRASP1 RPS2 TEX2 RPS6 SH3GL2 ARL8A BCR AP3M1 CCT6A KCNA1 NF1 SHANK2 HPCAL1 KCTD16 OSBPL8 PCCB TMCC1 HDLBP

1.51e-0611391461836417873
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

NUSAP1 TCP1 FBL RPS2 RPS6 PEX1 SRP54 CHD8 PRPF6 AP3M1 DNAH7 PDIA4 CCT6A AGO1 SMG7 PABPC3 CCT6B CDC73

1.79e-0611531461829845934
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3B CNTNAP3 NGEF MTCL1

2.06e-0622146426494785
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

TCP1 FBL RPS2 RPS6 PRPF6 CCT6A PABPC3 OSBPL8 PCCB

2.44e-06272146925315684
Pubmed

Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea.

SOX2 GATA3 PROX1

2.51e-067146328118374
Pubmed

Continued expression of GATA3 is necessary for cochlear neurosensory development.

SOX2 GATA2 GATA3 PROX1

2.97e-0624146423614009
Pubmed

Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei.

SOX2 GATA2 GATA3 ZFPM2

3.52e-0625146426718003
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TCF20 TEX2 DCP2 BCR TESK1 LYST DNAH7 NF1 DLC1 SAMD11 CCSER2 OSBPL8 PLEKHM3 MTCL1 TMCC1

3.74e-068611461536931259
Pubmed

Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.

SOX2 GATA2 GATA3

4.00e-068146329197504
Pubmed

Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors.

SOX2 TP73 PROX1

4.00e-068146339268037
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TCF20 FBL RPS2 RPS6 NSD1 CHD8 DDX51 SPAG9 PRPF6 PDIA4 NF1 OSBPL8 HDLBP

4.15e-066531461322586326
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ABCC4 SLC22A23 TRPM2 SRP54 BCR GRHL2 ZNF462 USP14 SHANK2 PTPRE SMG7 HPCAL1 PTPRR LOXL2 NGEF SLC9A7 CDYL2 MICAL3 DENND5A TMCC1

4.48e-0614891462028611215
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

KIF18A TCF20 PRPF6 AP3M1 ZNF518A ZNF462 SENP6 CDC73

4.81e-06222146837071664
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TCP1 TEX2 NAGA CHD8 AP3M1 CFB KRIT1 NF1 AGO1 NGEF HDLBP

5.75e-064751461131040226
Pubmed

Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons.

SOX2 GATA3 PROX1

5.98e-069146325411508
Pubmed

Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.

SOX2 ITGA6 ITGA9

5.98e-069146334133940
Pubmed

Antibody characterisation of two distinct conformations of the chaperonin-containing TCP-1 from mouse testis.

TCP1 CCT6A CCT6B

5.98e-06914637828721
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

DNAH3 TCP1 FBL RPS2 RPS6 PRPF6 ARL8A ZFPM2 PDIA4 CCT6A NF1 ARL8B CCT6B HDLBP

7.94e-068031461436517590
Pubmed

Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

TCP1 CCT6A CCT6B

8.51e-061014637953530
Pubmed

Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions.

SOX2 TP73 PROX1

8.51e-0610146328945921
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

SOX2 ZFPM2 PPP1R3A ZNF462 KCNA1 DLC1 PTPRE MGAT4C PROX1

8.61e-06318146916919269
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRA PTPRE PTPRR

1.17e-051114637832766
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

NUSAP1 WAPL FBL RPS2 RPS6 CHD8 DDX51 PRPF6 PDIA4 SAMD11 CDC73 HDLBP

1.39e-056241461233729478
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DCDC1 TCP1 RPS2 RPS6 CCT6A PABPC3 CCT6B

1.50e-05187146726460568
Pubmed

Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.

ARL8A ARL8B

1.75e-052146214871887
Pubmed

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.

AGO1 AGO4

1.75e-052146233233493
Pubmed

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.

GATA2 GATA3

1.75e-052146216055713
Pubmed

Long non-coding RNA PROX1-AS1 knockdown upregulates microRNA-519d-3p to promote chemosensitivity of retinoblastoma cells via targeting SOX2.

SOX2 PROX1

1.75e-052146234583623
Pubmed

During development intense Sox2 expression marks not only Prox1-expressing taste bud cell but also perigemmal cell lineages.

SOX2 PROX1

1.75e-052146225532873
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

1.75e-052146226807827
Pubmed

In Uncontrolled Diabetes, Hyperglucagonemia and Ketosis Result From Deficient Leptin Action in the Parabrachial Nucleus.

LEPR CCK

1.75e-052146229438473
Pubmed

GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.

GATA2 GATA3

1.75e-052146219371385
Pubmed

An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.

ARL8A ARL8B

1.75e-052146216537643
Pubmed

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.

ARL8A ARL8B

1.75e-052146230174114
Pubmed

The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development.

GATA2 GATA3

1.75e-052146238346193
Pubmed

Gata3 is required in late proneurosensory development for proper sensory cell formation and organization.

SOX2 GATA3

1.75e-052146237537240
Pubmed

The essential role of GATA transcription factors in adult murine prostate.

GATA2 GATA3

1.75e-052146227374105
Pubmed

GATA3 is downregulated during hair cell differentiation in the mouse cochlea.

GATA2 GATA3

1.75e-052146210447238
Pubmed

Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation.

GATA2 GATA3

1.75e-052146219106099
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

1.75e-052146231150793
Pubmed

A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome.

GATA3 ZFPM2

1.75e-052146219723756
Pubmed

Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo.

PTPRA PTPRE

1.75e-052146230615487
Pubmed

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.

GATA2 GATA3

1.75e-052146215328158
Pubmed

An unexpected protein interaction promotes drug resistance in leukemia.

MPP1 ABCC4

1.75e-052146229146910
Pubmed

A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα.

LEPR ZFPM2

1.75e-052146227207553
Pubmed

Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance.

LEPR CCK

1.75e-052146225383904
Pubmed

GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene.

GATA2 GATA3

1.75e-05214627720565
Pubmed

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts.

PTPRA PTPRE

1.75e-052146224694598
Pubmed

Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.

PTPRA PTPRE

1.75e-052146216870705
Pubmed

Regulation of dendritic arborization by BCR Rac1 GTPase-activating protein, a substrate of PTPRT.

BCR PTPRT

1.75e-052146222767509
Pubmed

Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.

AGO1 AGO4

1.75e-052146226995025
Pubmed

Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome.

GATA3 ZFPM2

1.75e-052146214985365
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

BCR DLC1 NGEF ARHGAP29

1.97e-0538146419911011
Pubmed

V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion.

GATA2 GATA3 LBX1

2.01e-0513146324698273
Pubmed

VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance.

GATA2 ITGA9 PROX1

2.01e-0513146331461654
Pubmed

Lens induction requires attenuation of ERK signaling by Nf1.

SOX2 NF1 PROX1

2.01e-0513146321233129
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

MPP1 RPS2 SH3GL2 SPAG9 JADE1 CFAP298 LEPR PDIA4 SETDB1 PTPRA CCSER2 NGEF HAAO CDC73 DENND5A DNMT3B

2.17e-0511241461621900206
Pubmed

Profiling of Parkin-binding partners using tandem affinity purification.

TCP1 RPS2 RPS6 PRPF6 PDIA4 PABPC3 PCCB

2.54e-05203146724244333
Pubmed

Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus.

SOX2 TP73 PROX1

2.55e-0514146323447624
Pubmed

Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.

SOX2 GATA3 PROX1

2.55e-0514146321146598
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

RPS2 TEX2 SRP54 BCR ARHGAP29 MICAL3 MTCL1

3.06e-05209146736779422
Pubmed

TGF-β Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups.

GATA2 GATA3 CCK

3.18e-0515146329689292
Pubmed

The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.

TCP1 CCT6A CCT6B

3.18e-0515146330955883
Pubmed

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.

ITGA6 ITGA9 PROX1

3.18e-0515146323299940
Pubmed

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.

SOX2 GATA3 PROX1

3.90e-0516146322292060
Pubmed

Specification of neurotransmitter identity by Tal1 in thalamic nuclei.

SOX2 GATA2 GATA3

3.90e-0516146328685891
Pubmed

Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.

GATA2 ITGA9 PROX1

3.90e-0516146326542011
Pubmed

Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.

SOX2 RPS6 PROX1

3.90e-0516146336440598
Pubmed

Hdac3 regulates lymphovenous and lymphatic valve formation.

GATA2 ITGA9 PROX1

3.90e-0516146329035278
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPRA PTPRE PTPRR

4.72e-0517146319727691
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CHD8 SPAG9 ZNF518A ZNF462 NLN SMG7 OSBPL8

4.89e-05225146712168954
Pubmed

GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.

GATA2 GATA3

5.24e-053146212041667
Pubmed

HBV suppresses expression of MICA/B on hepatoma cells through up-regulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance.

GATA2 GATA3

5.24e-053146227528231
Pubmed

GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia.

GATA2 GATA3

5.24e-053146217654061
Pubmed

Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells.

GATA2 GATA3

5.24e-053146236806146
Pubmed

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.

GATA2 GATA3

5.24e-053146218202227
Pubmed

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.

LEPR DGAT2

5.24e-053146232561790
Pubmed

Confirmation of mutation landscape of NF1-associated malignant peripheral nerve sheath tumors.

NF1 KDM2B

5.24e-053146228124441
Pubmed

Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns.

LEPR CCK

5.24e-053146217192493
Pubmed

The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

SETDB1 DNMT3B

5.24e-053146216682412
Pubmed

Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells.

PTPRA PTPRE

5.24e-053146212598528
Pubmed

Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.

PTPRA PTPRE

5.24e-053146219812040
Pubmed

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.

AGO1 AGO4

5.24e-053146219946268
Pubmed

Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades.

ITGA9 PROX1

5.24e-053146217287396
Pubmed

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors.

SOX2 SRY

5.24e-053146219349578
Pubmed

JADE1 is dispensable for the brain development in mice.

SOX2 JADE1

5.24e-053146238171233
Pubmed

CD49f enhances multipotency and maintains stemness through the direct regulation of OCT4 and SOX2.

SOX2 ITGA6

5.24e-053146222311737
Pubmed

Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.

GATA2 GATA3

5.24e-053146228232602
Pubmed

Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1.

CCT6A CCT6B

5.24e-05314629013858
Pubmed

Dynamic regulation of Gata factor levels is more important than their identity.

GATA2 GATA3

5.24e-053146217327407
Pubmed

Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase.

POLB DNMT3B

5.24e-053146231963223
Pubmed

Neurochemical characterization of body weight-regulating leptin receptor neurons in the nucleus of the solitary tract.

LEPR CCK

5.24e-053146222869346
Pubmed

MPP1 links the Usher protein network and the Crumbs protein complex in the retina.

MPP1 PALS1

5.24e-053146217584769
InteractionMARK2 interactions

SOX2 GPRASP1 TRAPPC11 ARL8A SSTR3 PTPRA NF1 AGO1 AGO4 ARL8B MTCL1 HDLBP

6.14e-0727414312int:MARK2
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRT PTPRA PTPRE PTPRR

6.19e-06211064813
GeneFamilyChaperonins

TCP1 CCT6A CCT6B

8.47e-05151063587
GeneFamilyArgonaute/PIWI family

AGO1 AGO4

9.32e-0481062408
CoexpressionCUI_TCF21_TARGETS_2_DN

SLC36A4 ARID4A TEX2 POLB GATA3 JADE1 ITGA9 LYST KRIT1 ZNF518A PALS1 AGO4 GVINP1 ARL8B ARHGAP31 LOXL2 ARHGAP29 OSBPL8 MTCL1 CDC73

6.22e-0885414620M1533
CoexpressionCUI_TCF21_TARGETS_2_DN

SLC36A4 ARID4A TEX2 POLB GATA3 JADE1 ITGA9 LYST KRIT1 ZNF518A PALS1 AGO4 ARL8B ARHGAP31 LOXL2 ARHGAP29 OSBPL8 MTCL1 CDC73

5.41e-0788814619MM1018
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GPRASP1 ARID4A GATA3 PEX1 ARL8A CSMD2 LYST PTPRT ZFPM2 GPD1L ZNF462 NLN SHANK2 SAMD11 NGEF SLC9A7 KDM2B MICAL3 MGAT4C

1.30e-05110614619M39071
CoexpressionGSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN

GATA3 BCR GPD1L DLC1 HPCAL1 CCT6B HAAO ABCD2

1.59e-051981468M8379
CoexpressionGSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN

ASAH2 GATA3 POU6F1 DNAH7 KRIT1 AGO4 HAAO CNN2

1.71e-052001468M386
CoexpressionGSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN

MPP1 NUSAP1 C6orf62 NAGA ITGA6 LYST PLEKHM3 TMCC1

1.71e-052001468M8651
CoexpressionGSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN

TEX2 PEX1 ITGA6 SPAG9 POU6F1 LYST ARID5A DENND5A

1.71e-052001468M6943
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

WAPL ARID4A ITGA6 SPAG9 KRIT1 SETDB1 PTPRA DLC1 HPCAL1 CCSER2 ARHGAP29 OSBPL8 MICAL3 MTCL1 DENND5A TMCC1

2.42e-0585614616M4500
CoexpressionGSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP

ASAH2 DDX51 SPAG9 CFAP298 CFB ARL8B ZFYVE26

4.17e-051661467M8987
CoexpressionGSE14415_ACT_VS_CTRL_NATURAL_TREG_DN

FBL POLB PRPF6 PALS1 HPCAL1 CARD6 TMCC1

4.50e-051681467M2962
CoexpressionGSE21033_1H_VS_12H_POLYIC_STIM_DC_UP

MPP1 PCYT1A GATA3 ITGA6 JADE1 ARHGAP31 SLC9A7

6.05e-051761467M7725
CoexpressionGSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP

TEX2 ASAH2 NSD1 GPD1L AGO1 CDYL2 DNMT3B

7.21e-051811467M8579
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

WAPL C6orf62 TCP1 ARID4A RPS2 DCP2 GATA2 GATA3 NSD1 JADE1 AP3M1 LYST ARID5A TRANK1 PTPRA PTPRE GVINP1 CCSER2 OSBPL8 SENP6 CNN2

8.30e-05149214621M40023
CoexpressionGSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_UP

GPRASP1 ARID4A GVINP1 HPCAL1 CCSER2 CCT6B PCCB

1.22e-041971467M9730
CoexpressionNUTT_GBM_VS_AO_GLIOMA_DN

RPS6 PRPF6 BCR PDE8B

1.26e-04461464M2577
CoexpressionGSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP

TCF20 ITGA6 POU6F1 GPD1L AGO4 OSBPL8 CNN2

1.26e-041981467M4408
CoexpressionGSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP

DCP2 GATA2 DDX51 BCR CCK PTPRA ZFYVE26

1.30e-041991467M5205
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP

TCP1 CHD8 DNAH7 PDIA4 CCSER2 OSBPL8 MTCL1

1.30e-041991467M5235
CoexpressionGSE360_L_DONOVANI_VS_T_GONDII_MAC_UP

SRP54 DNAH7 PDIA4 LBX1 CCSER2 CCT6B DENND5A

1.30e-041991467M5233
CoexpressionGSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN

GPRASP1 SLC25A27 TCF20 CARD6 ARHGAP29 SENP6 TMCC1

1.30e-041991467M9253
CoexpressionGSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN

GPRASP1 TRAPPC11 C6orf62 SLC36A4 ARID4A TEX2 MAP2K6

1.34e-042001467M7505
CoexpressionGSE6674_CPG_VS_PL2_3_STIM_BCELL_DN

TEX2 PEX1 ARMCX4 PTPRE SENP6 SYPL1 HDLBP

1.34e-042001467M6938
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL NSD1 ITGA6 SRP54 SPAG9 LYST CCT6A GVINP1 ARHGAP29

7.86e-09178146901dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ZFPM2 PTPRE ARHGAP29 MGAT4C PROX1

1.52e-081921469cbe57cda44232b183821ac633b60a2668265e616
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SPAG9 CSMD2 PTPRT PTPRE NGEF MICAL3 DENND5A

1.36e-071781468a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ZFPM2 PTPRE MICAL3 PROX1

2.06e-071881468c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ZFPM2 PTPRE MICAL3 PROX1

2.24e-0719014686e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

CNTNAP3B SLC22A23 ITGA9 ZFPM2 DLC1 ARHGAP29 MGAT4C PROX1

2.52e-07193146825bdc557055b5bce6a21f8696b48e991c696b979
ToppCellControl-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

RPS2 SLC22A23 ITGA9 ZFPM2 PTPRE MICAL3 MGAT4C PROX1

2.83e-071961468e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

CSMD2 ZNF518A AGO1 AGO4 SAMD11 HFM1 TMCC1

3.21e-0713514673351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SLC22A23 ITGA9 ZFPM2 PTPRE DCAF12L1 PROX1

1.52e-0617014676035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SLC22A23 ITGA9 ZFPM2 PTPRE DCAF12L1 PROX1

1.52e-061701467c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SLC22A23 ITGA9 ZFPM2 PTPRE DCAF12L1 PROX1

1.52e-061701467dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

CNTNAP3B ITGA9 ZFPM2 PTPRE ARHGAP29 MGAT4C PROX1

1.91e-06176146798c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRASP1 NSD1 SRP54 PRPF6 LYST CCT6A HDLBP

1.91e-061761467749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

CNTNAP3B ITGA9 ZFPM2 PTPRE ARHGAP29 MGAT4C PROX1

1.91e-061761467c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ZFPM2 PTPRE PROX1

1.98e-061771467326fde0734ef0d7272693966d346ca479b9d8147
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ARHGAP29 MGAT4C PROX1

2.30e-061811467b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ARHGAP29 MGAT4C PROX1

2.30e-061811467dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

2.47e-0618314674d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCelltumor_Lung-Myeloid_cells-CD141+_DCs|tumor_Lung / Location, Cell class and cell subclass

NAGA PPP1R3A PTPRE SLC24A4 DGAT2 MAP2K6 CNN2

2.56e-061841467f5cad8eb358898ae536cd7a7b37d3ce19528b801
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

CNTNAP3B ITGA9 ZFPM2 PTPRE ARHGAP29 MGAT4C PROX1

2.66e-0618514674a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

CNTNAP3B ITGA9 ZFPM2 PTPRE ARHGAP29 MGAT4C PROX1

2.66e-06185146736ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

2.75e-06186146740070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA2 NSD1 SRP54 LYST CCT6A ARHGAP31 ARHGAP29

2.75e-0618614670ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 MICAL3 MGAT4C PROX1

2.85e-0618714671e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 PTPRE ARHGAP29 PROX1

2.96e-06188146780910dcbb51990f2baed240f319456c0d3fa2065
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.06e-061891467c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DCDC1 GRHL2 DNAH7 ZNF462 KCTD16 ARHGAP29

3.06e-061891467904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 MICAL3 MGAT4C PROX1

3.17e-06190146791bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

CNTNAP3B SLC22A23 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.40e-0619214672496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.40e-061921467f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A GATA2 ITGA6 DLC1 SLC24A4 ARHGAP31 ARHGAP29

3.40e-0619214674bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.40e-061921467690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

CNTNAP3B SLC22A23 ITGA9 ZFPM2 DLC1 ARHGAP29 PROX1

3.51e-06193146718bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.51e-061931467294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.51e-0619314673d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.64e-061941467f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.64e-0619414676ac759828c41ffa974ee82842162caa959351dd1
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL NSD1 ITGA6 SPAG9 CCT6A ARHGAP31 SENP6

3.64e-061941467e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.64e-0619414673b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

3.64e-0619414675d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.64e-0619414675d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RPS2 PTPRE SLC12A3 DGAT2 SLC9A7 MAP2K6 CNN2

3.64e-061941467d21461682fa755f588afe073abb6a777f339c4cc
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DCDC1 SLC22A23 GRHL2 DNAH7 PTPRT SHANK2

3.76e-061951467fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellBAL-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

ZNF462 PTPRE SLC24A4 DGAT2 SLC9A7 PLEKHM3 MAP2K6

3.76e-0619514672d31a1c2878c86a49a278b6c7decafabf26c3a5c
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPP1 CNTNAP3B LINC00305 CNTNAP3 GATA3 LEPR PTPRE

3.76e-061951467ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DCDC1 SLC22A23 GRHL2 DNAH7 PTPRT SHANK2

3.76e-061951467eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellPCW_13-14-Endothelial-Endothelial_mature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B CNTNAP3 GATA2 ITGA6 LEPR PTPRE ARHGAP29

3.76e-06195146731353269591c9eee84872838e91995d4a035da46
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH3 DCDC1 SLC22A23 GRHL2 DNAH7 PTPRT SHANK2

3.89e-06196146787d9881cfec461a5d89b688a83749b618c519485
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

CNTNAP3B GATA2 ITGA6 ITGA9 HPCAL1 ARHGAP31 ARHGAP29

4.02e-061971467ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC36A4 POLB ASAH2 SCG2 MAP2K6 PCCB PROX1

4.16e-06198146762059185afdf66126a6fbc899ce611c47e7a0feb
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 PTPRE MGAT4C PROX1

4.16e-061981467b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 PTPRE MGAT4C PROX1

4.16e-061981467fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCelldistal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH3 DCDC1 SH3GL2 DNAH7 PTPRT CXorf58 TP73

4.44e-062001467f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX2 PTPRT ZNF462 HPCAL1 ARHGAP31 MGAT4C PROX1

4.44e-062001467e90155498397524b812c46f2412320230b445bb6
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

RPS2 RPS6 ITGA6 SSTR3 TRANK1 CCSER2 ABCD2

4.44e-062001467deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SLC22A23 ITGA9 GRHL2 FAAH2 SHANK2

4.51e-0613014666434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP3B SLC22A23 CNTNAP3 ITGA9 ZFPM2 PROX1

9.50e-061481466f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

CSMD2 ZNF518A AGO1 AGO4 HFM1 TMCC1

9.87e-061491466768877bade04ca0321593b8470b5011ad8270431
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH3 DCDC1 GRHL2 DNAH7 PTPRT SHANK2

1.07e-0515114668216462e723fec2797387929dde095370947e10a
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ADAD1 GATA2 ITGA9 DLC1 HFM1 DNMT3B

1.38e-0515814660d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 SLC22A23 ITGA6 JADE1 SLC12A3 TP73

1.48e-0516014661e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TRAV2 GATA3 SSTR3 LYST NEIL3 SPOCD1

1.59e-051621466a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 PTPRT PTPRR SEPTIN14 EGFLAM MGAT4C

1.64e-05163146619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

SOX2 ABCC4 GRHL2 LYST PTPRE CDYL2

1.64e-051631466d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

CNTNAP3B GATA2 ITGA6 LEPR PTPRR ARHGAP29

1.76e-05165146684e553d699ac56df89a77248f7308b9133e1b683
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCDC1 DNAH7 SHANK2 KCTD16 MICAL3 MGAT4C

1.95e-051681466a086c306be430adf0632ba53e98cd8014d2de330
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF462 SLC12A3 SLC24A4 DGAT2 SLC9A7 PLEKHM3

2.02e-051691466e3410ccb3f85811c75694e286115803911169a2f
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF462 SLC12A3 SLC24A4 DGAT2 SLC9A7 PLEKHM3

2.02e-051691466a4f610d07c3ba5537f4497f523669b914f7eddc1
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC4 GATA3 JADE1 PTPRE PTPRR CCSER2

2.09e-05170146655fe16d98ea284d05fb899888e4569c685644c7b
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 MGAT4C PROX1

2.30e-051731466dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

KIF18A GATA2 ITGA9 MTCL1 DENND5A DNMT3B

2.54e-051761466b9da3deaf62622d47eb30b6be7548253eee95597
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 CARD6 ARHGAP29 EGFLAM MGAT4C PROX1

2.62e-051771466dfaed388926ce050730492a532824af68bf4feff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B CNTNAP3 ZFPM2 KCNA1 DLC1 NGEF

2.62e-051771466bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA2 ITGA9 LEPR PTPRE ARHGAP29 PROX1

2.62e-0517714666248c0dcad302de61a66163ee84b3b79096150d7
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NUSAP1 KIF18A GATA2 ITGA6 ARHGAP29 NEIL3

2.70e-051781466ea10117026021c959ffc871fc377cdb3e161d264
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 GATA2 ITGA9 PTPRE ARHGAP29 PROX1

2.70e-0517814664b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

2.70e-051781466ad3de3e03a401dac64431a541899445262246347
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B CNTNAP3 ZFPM2 KCNA1 DLC1 NGEF

2.79e-0517914667954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3B CNTNAP3 ZFPM2 GPD1L EGFLAM ABCD2

2.79e-05179146614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 ZFPM2 DLC1 PTPRE ARHGAP29 PROX1

3.06e-051821466fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 NSD1 SRP54 LYST CCT6A SENP6

3.06e-051821466e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 NSD1 SRP54 LYST CCT6A SENP6

3.06e-0518214661710eab3037a87609d21838be2d2d29c3bc36651
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3B CNTNAP3 ZFPM2 ZNF462 KDM2B EGFLAM

3.06e-0518214667b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B CNTNAP3 ITGA9 ZFPM2 MGAT4C PROX1

3.06e-05182146653c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX2 SH3GL2 FAAH2 SCG2 TP73 PROX1

3.06e-051821466dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 ITGA9 ZFPM2 SLC24A4 HPCAL1 NGEF

3.16e-0518314661645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 ITGA9 ZFPM2 SLC24A4 HPCAL1 NGEF

3.25e-05184146634e316ad8e7b8667cd8ad61397281802a252744f
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 ZFPM2 DLC1 PTPRE ARHGAP29 PROX1

3.25e-051841466453295362888c9a59d0e73c7a5b15914c50ff591
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 ITGA6 PTPRE ARHGAP29 PROX1

3.35e-051851466f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX2 DNAH3 DCDC1 DNAH7 PTPRT TP73

3.35e-0518514663e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

CNTNAP3B ITGA9 PTPRE ARHGAP29 MGAT4C PROX1

3.35e-05185146697a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ARMCX4 ITGA9 BCR ZFPM2 PROX1

3.46e-051861466f23f21781a758541f59c06efa7739d26a03fb478
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|normal_Lung / Location, Cell class and cell subclass

PTPRE SLC12A3 SLC24A4 DGAT2 SLC9A7 CNN2

3.46e-051861466a6698a2f4edd81b67e06531ede0e207dd0309205
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ARMCX4 ITGA9 BCR ZFPM2 PROX1

3.46e-0518614660de87109da9324c597fadf2eb782f0f158afe832
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B ABCC4 ZNF462 KCTD16 MICAL3 MTCL1

3.46e-051861466b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B ITGA9 ZFPM2 ARHGAP29 MGAT4C PROX1

3.46e-05186146620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

ABCC4 GATA2 ZNF462 DLC1 ARHGAP29 MTCL1

3.56e-051871466f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

ABCC4 GATA2 ZNF462 DLC1 ARHGAP29 MTCL1

3.56e-051871466da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

CNTNAP3B ABCC4 GATA2 ITGA9 BCR ARHGAP31

3.56e-05187146640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPS6 GATA2 GATA3 ARMCX4 PTPRR ARHGAP31

3.67e-0518814665bc1537e079c7435196c163bff5f639ea392a33a
DrugGemfibrozil [25812-30-0]; Down 200; 16uM; HL60; HG-U133A

NUSAP1 PCYT1A TRAPPC11 DNAH3 RPS2 TRPM2 PRPF6 KRIT1 HAAO

4.98e-0619714591430_DN
DrugCyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; HL60; HT_HG-U133A

DNAH3 RPS2 PRPF6 NF1 AGO4 CCSER2 CCT6B MAP2K6 DNMT3B

5.19e-0619814591332_DN
DiseaseMalignant neoplasm of breast

TCP1 FBL RPS6 GATA3 ITGA9 TESK1 LEPR PPP1R3A TRMT10A NF1 LBX1 LOXL2 ARHGAP29 ZFYVE26 SPOCD1 TP73 DNMT3B HDLBP

4.79e-06107414318C0006142
Diseasevenous thromboembolism, fibrinogen measurement

LEPR ZFPM2 PCCB HDLBP

3.20e-04671434EFO_0004286, EFO_0004623
Diseaseprimary ciliary dyskinesia (is_implicated_in)

DNAH7 TP73

3.45e-0461432DOID:9562 (is_implicated_in)
DiseaseManic

TRPM2 CCK TRANK1 SHANK2

5.71e-04781434C0338831
DiseaseGonadal Dysgenesis, 46,XY

SRY ZFPM2

6.41e-0481432C0018054
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

6.41e-0481432DOID:0060308 (implicated_via_orthology)
DiseaseBurkitt Lymphoma

GATA3 BCR CCT6B

7.08e-04361433C0006413
Diseaseacute myeloid leukemia (is_implicated_in)

GATA2 NSD1 NF1 DNMT3B

7.56e-04841434DOID:9119 (is_implicated_in)
Diseasecystic fibrosis (implicated_via_orthology)

ABCC4 ABCB5

8.21e-0491432DOID:1485 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP3B TCF20 CNTNAP3 CHD8 SHANK2

8.91e-041521435DOID:0060041 (implicated_via_orthology)
Diseaseautistic disorder (is_implicated_in)

SETDB1 NF1 SHANK2

1.11e-03421433DOID:12849 (is_implicated_in)
Disease46,XY partial gonadal dysgenesis

SRY ZFPM2

1.25e-03111432C4510744
DiseasePancreatic Ductal Adenocarcinoma

ABCB5 ABCD2

1.25e-03111432C1335302
DiseaseGastrointestinal Diseases

CHD8 CCK

1.49e-03121432C0017178
DiseaseFunctional Gastrointestinal Disorders

CHD8 CCK

1.49e-03121432C0559031
DiseaseCholera Infantum

CHD8 CCK

1.49e-03121432C1565321
Diseaseacute myeloid leukemia (is_marker_for)

GATA2 NF1 DNMT3B

1.74e-03491433DOID:9119 (is_marker_for)
DiseaseAutistic Disorder

NSD1 CHD8 NF1 AGO1 SHANK2 HDLBP

1.76e-032611436C0004352
Diseasepeptide measurement

LINC00305 PTPRT NLN DLC1

1.98e-031091434EFO_0010520
DiseaseSarcoma, Spindle Cell

SOX2 NF1

2.04e-03141432C0205945
DiseaseSarcoma, Epithelioid

SOX2 NF1

2.04e-03141432C0205944
Diseaseglucose-dependent insulinotropic peptide measurement

SETDB1 SLC24A4 CARD6

2.19e-03531433EFO_0008464
Diseaseseasonal gut microbiome measurement

DCDC1 ZFPM2 TRMT10A PTPRR

2.19e-031121434EFO_0007753
Diseasequinate measurement

LEPR CFB

2.35e-03151432EFO_0021167
Diseasevascular endothelial growth factor measurement

ZFPM2 ZNF462 MTCL1

2.56e-03561433EFO_0004762
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

ZFPM2 SCG2

2.68e-03161432EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
DiseaseAntibody Deficiency Syndrome

LEPR DNMT3B

3.02e-03171432C0003257
Diseaseserine measurement, amino acid measurement

CCT6A SEPTIN14

3.02e-03171432EFO_0005134, EFO_0009774
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

LEPR DGAT2

3.39e-03181432DOID:0080208 (is_implicated_in)
Diseasecalcium measurement

ABCC4 GATA3 CHD8 ZFPM2 HPCAL1 HFM1 FER1L5 MAP2K6 PCCB

3.62e-036281439EFO_0004838
Diseaseanorectal malformation

TRPM2 CSMD2

3.78e-03191432MONDO_0019938
DiseaseJuvenile Myelomonocytic Leukemia

GATA2 NF1

3.78e-03191432C0349639
Diseasenon-word reading

SLC12A3 SLC24A4 PCCB

4.26e-03671433EFO_0005299
DiseasePrecursor B-cell lymphoblastic leukemia

GATA3 BCR

4.61e-03211432C1292769
Diseaseintrinsic cardiomyopathy (implicated_via_orthology)

CCT6A CCT6B

4.61e-03211432DOID:0060036 (implicated_via_orthology)
DiseaseSarcoma

SOX2 NF1

4.61e-03211432C1261473
DiseaseProfound Mental Retardation

NSD1 CHD8 NF1 SHANK2

4.75e-031391434C0020796
DiseaseMental Retardation, Psychosocial

NSD1 CHD8 NF1 SHANK2

4.75e-031391434C0025363
DiseaseMental deficiency

NSD1 CHD8 NF1 SHANK2

4.75e-031391434C0917816
DiseaseBreast Carcinoma

FBL RPS6 GATA3 LEPR LBX1 LOXL2 TP73 DNMT3B

4.83e-035381438C0678222

Protein segments in the cluster

PeptideGeneStartEntry
QDVLRTNLGPKGTMK

CCT6A

31

P40227
MAAPVKGNRKQSTEG

ARID5A

1

Q03989
MEPVQTANSRNGKKG

CHD8

2381

Q9HCK8
MGDPNSRKKQALNRL

C6orf62

1

Q9GZU0
KGASLQVDQLPQKMQ

CNTNAP3

886

Q9BZ76
IPIQRKGKNGVAIMS

EGFLAM

326

Q63HQ2
GQSSPEKKIRIENGM

ARID4A

861

P29374
QGKKQPAMLRVTGFQ

CSMD2

3286

Q7Z408
MNRSSNVPRKGILKS

CXorf58

1

Q96LI9
QRRKDQMQPGGTAIS

CDC73

406

Q6P1J9
IKQGKNQLFPVVMNG

DNMT3B

781

Q9UBC3
QKLESQLAGIPKMQQ

ABCD2

701

Q9UBJ2
QLKVMFIGGPNTRKD

HAAO

31

P46952
RLMGKGQVQLDPQAL

BCR

996

P11274
PNKFNTLVGEKGAQM

ABCB5

511

Q2M3G0
KEFLLLGPQQGTQMK

GVINP1

211

Q7Z2Y8
QLRKISKDAGMPIQG

AGO1

471

Q9UL18
MNQLPKGSAQIKSQL

ADAD1

326

Q96M93
QSGEQKKRNGIMTNP

ANKRD50

1351

Q9ULJ7
LKGKNQSMRGNGRKQ

DCP2

311

Q8IU60
LRKISKDAGMPIQGQ

AGO4

466

Q9HCK5
FDITIGPKQNMGKTI

AP3M1

291

Q9Y2T2
KAPSGRMSIVKNLQN

CCK

71

P06307
NPGRKIAEMQGKLAT

CCDC154

521

A6NI56
SDGKIKVRGNVNTMP

ARMCX4

486

Q5H9R4
NRKLMAPVNGTQTAK

SLC24A4

61

Q8NFF2
SQSPGLVKQAKQMVG

NSD1

2571

Q96L73
LVKQAKQMVGGQQLP

NSD1

2576

Q96L73
QQEPQLLGTINAKMK

MTCL1

866

Q9Y4B5
MPLGKLSKQQIARGF

PARP3

216

Q9Y6F1
QVTNGQGENKMKNLP

SPAG9

656

O60271
ARKQKAQGMPESGVA

MFN1

291

Q8IWA4
PTVGFNMRKVTKGNV

ARL8B

51

Q9NVJ2
PTVGFNMRKITKGNV

ARL8A

51

Q96BM9
QQKRKIVLDPSGSMN

CFB

256

P00751
KNGNFEMSGVNQKIP

MGAT4C

436

Q9UBM8
GQSMRTEKGLKQLLP

DCDC1

1326

M0R2J8
GNLPANMKKARVIQI

PTPRE

446

P23469
RQGSMKKEFPQNLGG

MICAL3

746

Q7RTP6
AQFPNTLLGNPKKRM

KCNA1

56

Q09470
TMKTVLKIGPNNGKN

NEIL3

561

Q8TAT5
IKKGPVQLIQQSEMR

KCTD16

346

Q68DU8
KEMLNGQKLQGPQTS

GPD1L

291

Q8N335
NPSMVRKFGRNISKG

KIF18A

881

Q8NI77
TNMKPGKIFINKGNV

ASAH2

236

Q9NR71
PKNRGMVIVNGGLKQ

ZFPM2

1036

Q8WW38
GVRCNTPAMGLQKKL

LOXL2

421

Q9Y4K0
MAQQQTGSRKRKAPA

DCAF12L2

1

Q5VW00
GKGRMLQAISPKQSP

PCYT1A

306

P49585
AGKNFPENQILIKRM

PDE8B

761

O95263
GKRGNQSGKNVMVEP

FBL

76

P22087
MGKQNSKLRPEVLQD

HPCAL1

1

P37235
QNLMEFVGGEPSKKR

POU6F1

221

Q14863
PRLKAMTSQARKQNG

LCA10

116

Q71F78
MEGVGKPKIINSFTQ

LEPR

816

P48357
PANQGIRGKRVVLMK

KRIT1

81

O00522
DLQSIQMQLGPRKKV

ANKS4B

381

Q8N8V4
NNVKPIRLNGTKDSM

ITGA6

401

P23229
MNELKQQPINKGGVR

NUSAP1

216

Q9BXS6
QVTLRNKPKDQMGGH

PLEKHM3

466

Q6ZWE6
ASAPPQKQKQMLGER

PABPC3

546

Q9H361
FKMKPIGLQERRGSN

PTPRR

326

Q15256
KQKETQSGAQREMGP

PTPRT

786

O14522
QERKMGNPKISVAGI

PPP1R3A

541

Q16821
EPKRFGNQITMQRKS

HFM1

1096

A2PYH4
LVPGKSFQQQREAMK

PALS1

406

Q8N3R9
RMNGRTVGIVGNQPK

PCCB

346

P05166
QLLTPGKMSQRQGKE

OSBPL8

36

Q9BZF1
SQRNRQLPSDGKKMV

ABCC4

396

O15439
KVHGGMNKLPSVNQL

TP73

416

O15350
GQKINPVLRMFGQSI

ITGA9

416

Q13797
ANKFVQPLLGRKNEM

ARHGAP29

286

Q52LW3
EKRVPTQGMFDKNGI

CCSER2

96

Q9H7U1
NVNRPLTMKKEGIQT

GATA2

381

P23769
NRPLTMKKEGIQTRN

GATA3

351

P23771
IGRRNGQAPNEKMKQ

CFAP298

96

P57076
KSLRQKQGEGPMTYL

GRHL2

256

Q6ISB3
SNLPGSLLKEQKMNR

KDM2B

741

Q8NHM5
QKLRPASQQGVQMKT

CARD6

906

Q9BX69
QNGIKMTNEPPKGLR

DNAH3

3626

Q8TD57
PGQRRMILKQFEQGK

DDX51

541

Q8N8A6
KGKQEMETGQQPSGL

LINC00305

36

Q7Z4B0
GVKMTNEAPKGLRAN

DNAH7

3536

Q8WXX0
NNTPRNIGKDGKFQM

DENND5A

1206

Q6IQ26
MAAANKGNKPRVRSI

C20orf27

1

Q9GZN8
NRIKDVNPMINGIVK

FAAH2

76

Q6GMR7
RLKGQMKTQLSQRPF

LYST

1761

Q99698
MAQQQTGSRKRKAPA

DCAF12L1

1

Q5VU92
KGMISLKVIPNQQSR

MPP1

141

Q00013
DGMTIFGQRQTPKKR

LBX1

111

P52954
MSKRKAPQETLNGGI

POLB

1

P06746
RKNQSGTMFRPGQKV

PEX1

1266

O43933
CKGLFQKLQAMGNPR

CCDC103

191

Q8IW40
QKLQAMGNPRSVKEG

CCDC103

196

Q8IW40
KGASLQVDQLPQKMQ

CNTNAP3B

886

Q96NU0
SSMPGKNAVTLRNRK

DGAT2

246

Q96PD7
RTGNLPANMKKNRVL

PTPRA

551

P18433
KPSNVLINALGQVKM

MAP2K6

181

P52564
RTQAQIMPGARPKNK

GPRASP1

41

Q5JY77
GQRMSGFQINLNPLK

SYPL1

16

Q16563
GGNQKNSPDRVKRPM

SOX2

31

P48431
RISGGNDKQGFPMKQ

RPS6

51

P62753
QDVLRTNLGPKGTMK

CCT6B

31

Q92526
QKLQKMGFTDVGPNN

SEPTIN14

311

Q6ZU15
PTKGKQNVIMFVGLQ

SRP54

96

P61011
KGKEMNGRVSQITQP

SSTR3

366

P32745
ARQLMGNNIKPVVKV

FER1L5

176

A0AVI2
PGKRTVGDQMKKNQA

PRPF6

51

O94906
FTQKNRMNPEGDIKG

SLC22A23

386

A1A5C7
LLKNNMNKNGGTEPS

PROX1

96

Q92786
GPSALEQLLMQQKQK

SMG7

1111

Q92540
LKQGELQQMSGPKTS

NGEF

491

Q8N5V2
GKLTGPNNQKRERMD

SCG2

206

P13521
GSQGMPKRIVNAKIA

TCP1

221

P17987
NMGLKLGPALKIRAQ

SAMD11

586

Q96NU1
KFLKVSQGQLVVMQP

PDIA4

346

P13667
QQKNGVVMPDHGKRR

JADE1

646

Q6IE81
PRVMQRKQSLGKPDQ

DLC1

1246

Q96QB1
KKQGQLRTRPNMGAV

SETDB1

411

Q15047
LQQMNREKLAKPGEG

SHANK2

1631

Q9UPX8
PSGLQIMPLKKSQNG

CDYL2

141

Q8N8U2
KLQPGSVPKINRSMQ

CNN2

66

Q99439
KMGKRNGLHLPEQVQ

NLN

171

Q9BYT8
NLTQGKMCLVPGKTR

TRAPPC11

651

Q7Z392
INTMSKIRGQEKGPG

SH3GL2

71

Q99962
ISVTGGAKNFNMKPR

TRPM2

171

O94759
GPFMEQRRSKGTKNL

SPOCD1

411

Q6ZMY3
MKGLRVAKAFQPSQG

nan

1

Q7L0L9
VIKSRIMNQPRDKQG

SLC25A27

251

O95847
GETTFMAKLGQKRPN

WAPL

36

Q7Z5K2
MGQPSQANTKKLLGT

NF1

2526

P21359
GRMKPNILVVGFKKN

SLC12A3

731

P55017
PKGSPQINRKSGQEM

TMCC1

131

O94876
LKGNPIGLNMLSNNK

SENP6

101

Q9GZR1
KMNKLPSNRGNTLRE

TESK1

86

Q15569
EGVTLRNKMTIPKNG

ARHGAP31

1401

Q2M1Z3
RNKMTIPKNGQRLET

ARHGAP31

1406

Q2M1Z3
FVNKKPGMVLTLNNG

ZNF518A

971

Q6AHZ1
PNKGMELKHGSQKLQ

TCF20

1171

Q9UGU0
NGRKSGVMLDPLQQQ

ZNF462

526

Q96JM2
NSKGNVQDRVKRPMN

SRY

51

Q05066
QLPLGNFVKMNSRKV

TRMT10A

231

Q8TBZ6
GKKGQNLAKITQQMP

HDLBP

381

Q00341
GQVSANMKIQKRIPR

TRANK1

936

O15050
PGKINSVEQNDMLRK

SLC9A7

161

Q96T83
MSQPKQKELAGSVRQ

TEX2

756

Q8IWB9
VLKIMPVQKQTRAGQ

RPS2

106

P15880
LTGVQPARQKVMVKG

USP14

36

P54578
KNLGKQTPSGSRQMD

ZFYVE26

1136

Q68DK2
QMKESKRFPQALNIG

SLC36A4

296

Q6YBV0
LVKGSKPSQQGRYNM

TRAV2

71

A0A0B4J234
NPKLMARLQKGGFDV

UGT2A2

141

P0DTE5
LMIKINQDPLGIQGR

NAGA

301

P17050