Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 CACNA1I CACNA1H HCN2	4.90e-09	152	74	9	GO:0022843
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 CACNA1I CACNA1H HCN2	2.36e-08	182	74	9	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 CACNA1I CACNA1H HCN2	2.60e-08	184	74	9	GO:0022832
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	NALCN HCN3 CACNA1I CACNA1H HCN2	3.77e-08	26	74	5	GO:0005248
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNH6 KCNG2 NALCN KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	5.21e-08	343	74	11	GO:0005261
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	1.00e-07	102	74	7	GO:0005249
GeneOntologyMolecularFunction	monoatomic ion channel activity	KCNH6 KCNG2 NALCN KCNH2 KCNG4 TPTE2 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	1.14e-07	459	74	12	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	1.31e-07	465	74	12	GO:0046873
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNH6 KCNG2 SLC12A9 KCNH2 KCNG4 HCN3 KCNN4 HCN2	1.91e-07	167	74	8	GO:0015079
GeneOntologyMolecularFunction	potassium channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	4.75e-07	128	74	7	GO:0005267
GeneOntologyMolecularFunction	channel activity	KCNH6 KCNG2 NALCN KCNH2 KCNG4 TPTE2 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	4.80e-07	525	74	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNH6 KCNG2 NALCN KCNH2 KCNG4 TPTE2 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	4.90e-07	526	74	12	GO:0022803
GeneOntologyMolecularFunction	sodium channel activity	NALCN HCN3 CACNA1I CACNA1H HCN2	1.38e-06	52	74	5	GO:0005272
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	3.06e-06	627	74	12	GO:0022890
GeneOntologyMolecularFunction	gated channel activity	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 CACNA1I CACNA1H HCN2	3.91e-06	334	74	9	GO:0022836
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 SLC27A1 TPTE2 HCN3 PKD1 SIDT1 KCNN4 CACNA1I CACNA1H HCN2 ABCA10	5.20e-06	1180	74	16	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	5.50e-06	664	74	12	GO:0008324
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 TPTE2 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	6.17e-06	793	74	13	GO:0015075
GeneOntologyMolecularFunction	transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 SLC27A1 TPTE2 HCN3 PKD1 SIDT1 KCNN4 CACNA1I CACNA1H HCN2 ABCA10	1.58e-05	1289	74	16	GO:0005215
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	2.07e-05	758	74	12	GO:0015318
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1I CACNA1H	4.05e-05	3	74	2	GO:0008332
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNH6 KCNH2 KCNN4	1.50e-04	28	74	3	GO:0005242
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNG2 KCNH2 KCNG4	1.50e-04	28	74	3	GO:0005251
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNH6 KCNH2 HCN3 KCNN4 HCN2	1.72e-04	140	74	5	GO:0099094
GeneOntologyMolecularFunction	CTPase activity	ENTPD7 ENTPD4	2.01e-04	6	74	2	GO:0043273
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	NALCN HCN3 CACNA1I CACNA1H HCN2	4.34e-04	171	74	5	GO:0015081
GeneOntologyMolecularFunction	UDP phosphatase activity	ENTPD7 ENTPD4	4.80e-04	9	74	2	GO:0045134
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN3 HCN2	5.98e-04	10	74	2	GO:0005222
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	KCNH6 KCNH2 HCN3 KCNN4 HCN2	7.52e-04	193	74	5	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	KCNH6 KCNH2 HCN3 KCNN4 HCN2	8.25e-04	197	74	5	GO:0022834
GeneOntologyMolecularFunction	GDP phosphatase activity	ENTPD7 ENTPD4	8.73e-04	12	74	2	GO:0004382
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN3 HCN2	1.03e-03	13	74	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN3 HCN2	1.03e-03	13	74	2	GO:0043855
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1I CACNA1H	1.20e-03	14	74	2	GO:0008331
GeneOntologyMolecularFunction	nucleoside diphosphate phosphatase activity	ENTPD7 ENTPD4	2.47e-03	20	74	2	GO:0017110
GeneOntologyMolecularFunction	pyrophosphatase activity	ENTPD7 TMEM250 IQCA1L GNA12 CHD1 YME1L1 ABCA10 ENTPD4 PLPP6	3.75e-03	839	74	9	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ENTPD7 TMEM250 IQCA1L GNA12 CHD1 YME1L1 ABCA10 ENTPD4 PLPP6	3.78e-03	840	74	9	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ENTPD7 TMEM250 IQCA1L GNA12 CHD1 YME1L1 ABCA10 ENTPD4 PLPP6	3.78e-03	840	74	9	GO:0016818
GeneOntologyMolecularFunction	cAMP binding	HCN3 HCN2	3.85e-03	25	74	2	GO:0030552
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 KCNN4 HCN2	1.45e-07	232	74	9	GO:0071805
GeneOntologyBiologicalProcess	potassium ion transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 KCNN4 HCN2	5.53e-07	272	74	9	GO:0006813
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	4.30e-06	922	74	14	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	5.51e-06	942	74	14	GO:0098655
GeneOntologyBiologicalProcess	action potential	KCNH6 KCNG2 KCNH2 KCNG4 CACNA1I CACNA1H HCN2	7.79e-06	201	74	7	GO:0001508
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 TPTE2 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	8.07e-06	1115	74	15	GO:0034220
GeneOntologyBiologicalProcess	membrane depolarization during action potential	KCNH2 CACNA1I CACNA1H HCN2	8.24e-06	36	74	4	GO:0086010
GeneOntologyBiologicalProcess	metal ion transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	1.09e-05	1000	74	14	GO:0030001
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	1.31e-05	1017	74	14	GO:0098660
GeneOntologyBiologicalProcess	monoatomic ion transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 TPTE2 HCN3 GAS6 PKD1 KCNN4 NMUR1 CACNA1I CACNA1H HCN2 GP1BB	2.33e-05	1374	74	16	GO:0006811
GeneOntologyBiologicalProcess	regulation of membrane potential	KCNH6 KCNG2 NALCN KCNH2 KCNG4 HCN3 KCNN4 CACNA1I CACNA1H HCN2	2.98e-05	559	74	10	GO:0042391
GeneOntologyBiologicalProcess	UDP catabolic process	ENTPD7 ENTPD4	3.80e-05	3	74	2	GO:0006256
GeneOntologyBiologicalProcess	pyrimidine nucleoside diphosphate catabolic process	ENTPD7 ENTPD4	3.80e-05	3	74	2	GO:0009140
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside diphosphate catabolic process	ENTPD7 ENTPD4	3.80e-05	3	74	2	GO:0009195
GeneOntologyBiologicalProcess	export from cell	IL11 SNX4 NRXN2 CLASP1 KCNH2 SLC27A1 PKD1 ARFGEF1 KCNN4 SCT CACNA1I CACNA1H TNFRSF11A NCKAP1L	5.25e-05	1153	74	14	GO:0140352
GeneOntologyBiologicalProcess	monoatomic cation transport	KCNH6 KCNG2 NALCN SLC12A9 KCNH2 KCNG4 HCN3 GAS6 PKD1 KCNN4 CACNA1I CACNA1H HCN2 GP1BB	5.45e-05	1157	74	14	GO:0006812
GeneOntologyBiologicalProcess	membrane depolarization	KCNH2 HCN3 CACNA1I CACNA1H HCN2	7.45e-05	121	74	5	GO:0051899
GeneOntologyBiologicalProcess	dephosphorylation	TPTE2 DUSP9 CTDSP1 GNA12 TIPRL PLPP6 NCKAP1L	2.46e-04	347	74	7	GO:0016311
GeneOntologyBiologicalProcess	UDP metabolic process	ENTPD7 ENTPD4	2.64e-04	7	74	2	GO:0046048
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside diphosphate metabolic process	ENTPD7 ENTPD4	2.64e-04	7	74	2	GO:0009193
GeneOntologyBiologicalProcess	negative regulation of endothelial cell apoptotic process	IL11 TNIP2 GAS6	3.98e-04	40	74	3	GO:2000352
GeneOntologyBiologicalProcess	positive regulation of transport	SNX4 CLASP1 OPN3 KCNH2 GAS6 KCNN4 SCT CACNA1I CACNA1H TNFRSF11A CDH1 NCKAP1L	4.37e-04	1081	74	12	GO:0051050
GeneOntologyBiologicalProcess	pyrimidine nucleoside diphosphate metabolic process	ENTPD7 ENTPD4	4.50e-04	9	74	2	GO:0009138
GeneOntologyBiologicalProcess	cell volume homeostasis	SLC12A9 KCNN4 SCT	4.60e-04	42	74	3	GO:0006884
GeneOntologyBiologicalProcess	positive regulation of exocytosis	SNX4 CLASP1 CACNA1I CACNA1H	5.96e-04	107	74	4	GO:0045921
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	SNX4 CLASP1 KCNN4 SCT CACNA1I CACNA1H TNFRSF11A	6.11e-04	404	74	7	GO:1903532
GeneOntologyCellularComponent	monoatomic ion channel complex	KCNH6 KCNG2 NALCN KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	1.02e-07	378	75	11	GO:0034702
GeneOntologyCellularComponent	cation channel complex	KCNG2 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	1.62e-07	235	75	9	GO:0034703
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	9.11e-07	91	75	6	GO:0008076
GeneOntologyCellularComponent	potassium channel complex	KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	2.00e-06	104	75	6	GO:0034705
GeneOntologyCellularComponent	transmembrane transporter complex	KCNH6 KCNG2 NALCN KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	2.50e-06	523	75	11	GO:1902495
GeneOntologyCellularComponent	transporter complex	KCNH6 KCNG2 NALCN KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H HCN2	4.04e-06	550	75	11	GO:1990351
GeneOntologyCellularComponent	plasma membrane protein complex	KCNG2 KCNH2 KCNG4 HCN3 KCNN4 CACNA1I GNA12 CACNA1H HCN2 CDH1 CDH15 GP1BB	2.15e-05	785	75	12	GO:0098797
GeneOntologyCellularComponent	caveola	SLC27A1 CACNA1H CDH1 PTGIS CDH15	4.95e-05	111	75	5	GO:0005901
GeneOntologyCellularComponent	membrane protein complex	KCNH6 KCNG2 SNX4 NALCN KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I GNA12 CACNA1H HCN2 CDH1 CDH15 GP1BB	6.70e-05	1498	75	16	GO:0098796
GeneOntologyCellularComponent	HCN channel complex	HCN3 HCN2	7.59e-05	4	75	2	GO:0098855
GeneOntologyCellularComponent	plasma membrane raft	SLC27A1 CACNA1H CDH1 PTGIS CDH15	1.87e-04	147	75	5	GO:0044853
GeneOntologyCellularComponent	voltage-gated sodium channel complex	CACNA1I CACNA1H	1.67e-03	17	75	2	GO:0001518
GeneOntologyCellularComponent	membrane raft	SLC27A1 CACNA1H TNFRSF11A CDH1 PTGIS CDH15	1.91e-03	362	75	6	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	SLC27A1 CACNA1H TNFRSF11A CDH1 PTGIS CDH15	1.96e-03	364	75	6	GO:0098857
GeneOntologyCellularComponent	calcium channel complex	PKD1 CACNA1I CACNA1H	2.30e-03	73	75	3	GO:0034704
MousePheno	abnormal channel response	KCNH6 NALCN CACNA1H HCN2	1.14e-05	33	60	4	MP:0003484
Domain	Ion_trans_dom	KCNH6 KCNG2 NALCN KCNH2 KCNG4 TPTE2 HCN3 CACNA1I CACNA1H HCN2	2.49e-11	114	74	10	IPR005821
Domain	Ion_trans	KCNH6 KCNG2 NALCN KCNH2 KCNG4 TPTE2 HCN3 CACNA1I CACNA1H HCN2	2.49e-11	114	74	10	PF00520
Domain	Channel_four-helix_dom	KCNG2 NALCN KCNG4 TPTE2 CACNA1I CACNA1H	9.73e-08	57	74	6	IPR027359
Domain	-	KCNG2 NALCN KCNG4 TPTE2 CACNA1I CACNA1H	9.73e-08	57	74	6	1.20.120.350
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH6 KCNH2 HCN3 HCN2	2.21e-07	14	74	4	IPR003938
Domain	CNMP_BINDING_1	KCNH6 KCNH2 HCN3 HCN2	7.51e-06	32	74	4	PS00888
Domain	CNMP_BINDING_2	KCNH6 KCNH2 HCN3 HCN2	7.51e-06	32	74	4	PS00889
Domain	cNMP	KCNH6 KCNH2 HCN3 HCN2	9.62e-06	34	74	4	SM00100
Domain	cNMP_binding	KCNH6 KCNH2 HCN3 HCN2	9.62e-06	34	74	4	PF00027
Domain	cNMP-bd_dom	KCNH6 KCNH2 HCN3 HCN2	1.08e-05	35	74	4	IPR000595
Domain	CNMP_BINDING_3	KCNH6 KCNH2 HCN3 HCN2	1.08e-05	35	74	4	PS50042
Domain	cNMP-bd-like	KCNH6 KCNH2 HCN3 HCN2	1.51e-05	38	74	4	IPR018490
Domain	-	KCNH6 KCNH2 HCN3 HCN2	3.87e-05	48	74	4	2.60.120.10
Domain	K_chnl_volt-dep_Kv6	KCNG2 KCNG4	4.63e-05	3	74	2	IPR003969
Domain	K_chnl_volt-dep_ERG	KCNH6 KCNH2	4.63e-05	3	74	2	IPR003967
Domain	VDCC_T_a1	CACNA1I CACNA1H	4.63e-05	3	74	2	IPR005445
Domain	RmlC-like_jellyroll	KCNH6 KCNH2 HCN3 HCN2	4.93e-05	51	74	4	IPR014710
Domain	Ion_trans_N	HCN3 HCN2	9.24e-05	4	74	2	PF08412
Domain	Ion_trans_N	HCN3 HCN2	9.24e-05	4	74	2	IPR013621
Domain	Sec7_N	GBF1 ARFGEF1	9.24e-05	4	74	2	IPR032691
Domain	Sec7_N	GBF1 ARFGEF1	9.24e-05	4	74	2	PF12783
Domain	GDA1_CD39_NTPase	ENTPD7 ENTPD4	4.27e-04	8	74	2	IPR000407
Domain	GDA1_CD39	ENTPD7 ENTPD4	4.27e-04	8	74	2	PF01150
Domain	GDA1_CD39_NTPASE	ENTPD7 ENTPD4	4.27e-04	8	74	2	PS01238
Domain	PAS_9	KCNH6 KCNH2	6.83e-04	10	74	2	PF13426
Domain	VDCCAlpha1	CACNA1I CACNA1H	6.83e-04	10	74	2	IPR002077
Domain	-	GBF1 ARFGEF1	1.57e-03	15	74	2	1.10.1000.11
Domain	Sec7	GBF1 ARFGEF1	1.57e-03	15	74	2	PF01369
Domain	Sec7_alpha_orthog	GBF1 ARFGEF1	1.57e-03	15	74	2	IPR023394
Domain	Sec7	GBF1 ARFGEF1	1.79e-03	16	74	2	SM00222
Domain	SEC7	GBF1 ARFGEF1	1.79e-03	16	74	2	PS50190
Domain	Sec7_dom	GBF1 ARFGEF1	1.79e-03	16	74	2	IPR000904
Domain	PAS-assoc_C	KCNH6 KCNH2	4.04e-03	24	74	2	IPR000700
Domain	PAS	KCNH6 KCNH2	4.38e-03	25	74	2	PF00989
Domain	Cadherin_cytoplasmic-dom	CDH1 CDH15	4.38e-03	25	74	2	IPR000233
Domain	PAS_fold	KCNH6 KCNH2	4.38e-03	25	74	2	IPR013767
Domain	Cadherin_C	CDH1 CDH15	4.38e-03	25	74	2	PF01049
Domain	PAC	KCNH6 KCNH2	4.73e-03	26	74	2	IPR001610
Domain	PAC	KCNH6 KCNH2	4.73e-03	26	74	2	SM00086
Domain	PAC	KCNH6 KCNH2	4.73e-03	26	74	2	PS50113
Domain	K_chnl_volt-dep_Kv	KCNG2 KCNG4	5.10e-03	27	74	2	IPR003968
Domain	hEGF	GAS6 NOTCH4	5.48e-03	28	74	2	PF12661
Domain	Catenin_binding_dom	CDH1 CDH15	5.87e-03	29	74	2	IPR027397
Domain	-	CDH1 CDH15	5.87e-03	29	74	2	4.10.900.10
Domain	VG_K_chnl	KCNG2 KCNG4	7.55e-03	33	74	2	IPR028325
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	9.76e-08	98	55	7	MM14545
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	1.38e-07	103	55	7	M1073
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNH6 KCNG2 KCNH2 KCNG4	1.89e-05	41	55	4	MM14546
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNH6 KCNG2 KCNH2 KCNG4	2.29e-05	43	55	4	M1056
Pathway	REACTOME_NEURONAL_SYSTEM	KCNH6 KCNG2 NRXN2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	4.30e-05	335	55	8	MM14503
Pathway	REACTOME_NEURONAL_SYSTEM	KCNH6 KCNG2 NRXN2 KCNH2 KCNG4 HCN3 KCNN4 HCN2	1.79e-04	411	55	8	M735
Pathway	REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS	ENTPD7 ENTPD4	4.12e-04	8	55	2	M27737
Pathway	REACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS	ENTPD7 ENTPD4	4.12e-04	8	55	2	MM15486
Pubmed	Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.	PKD1 GNA12 CDH1	1.00e-08	3	76	3	25492927
Pubmed	Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.	GNA12 CDH1 CDH15	2.00e-07	6	76	3	11136230
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNH6 KCNH2 HCN3 KCNN4 CACNA1H HCN2	6.35e-07	139	76	6	16985003
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNH6 KCNG2 KCNH2 KCNG4	1.81e-06	40	76	4	16382104
Pubmed	Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.	KCNH2 HCN3 HCN2	3.59e-06	14	76	3	29107716
Pubmed	A T-type calcium channel required for normal function of a mammalian mechanoreceptor.	CACNA1I CACNA1H	4.71e-06	2	76	2	12808460
Pubmed	Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.	HCN3 HCN2	4.71e-06	2	76	2	18033814
Pubmed	Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.	CACNA1I CACNA1H	4.71e-06	2	76	2	25071191
Pubmed	Hijacking components of the cellular secretory pathway for replication of poliovirus RNA.	GBF1 ARFGEF1	4.71e-06	2	76	2	17079330
Pubmed	Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.	CACNA1I CACNA1H	4.71e-06	2	76	2	36786913
Pubmed	Identification of polycystin-1 and Gα12 binding regions necessary for regulation of apoptosis.	PKD1 GNA12	4.71e-06	2	76	2	20837139
Pubmed	Gα12 is required for renal cystogenesis induced by Pkd1 inactivation.	PKD1 GNA12	4.71e-06	2	76	2	27505895
Pubmed	E-Cadherin Facilitates Protein Kinase D1 Activation and Subcellular Localization.	PKD1 CDH1	4.71e-06	2	76	2	26991955
Pubmed	HCN3 ion channels: roles in sensory neuronal excitability and pain.	HCN3 HCN2	4.71e-06	2	76	2	31290157
Pubmed	Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.	CACNA1I CACNA1H	1.41e-05	3	76	2	23488970
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH6 KCNH2	1.41e-05	3	76	2	14643686
Pubmed	T-type channels: release a brake, engage a gear.	CACNA1I CACNA1H	1.41e-05	3	76	2	26488564
Pubmed	Differential interactions of Na+ channel toxins with T-type Ca2+ channels.	CACNA1I CACNA1H	1.41e-05	3	76	2	18591418
Pubmed	Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.	CACNA1I CACNA1H	1.41e-05	3	76	2	11230107
Pubmed	Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization.	KCNH2 HCN2	1.41e-05	3	76	2	15961404
Pubmed	Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.	CACNA1I CACNA1H	1.41e-05	3	76	2	28846697
Pubmed	Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.	CACNA1I CACNA1H	1.41e-05	3	76	2	33547341
Pubmed	Calmodulin regulates Cav3 T-type channels at their gating brake.	CACNA1I CACNA1H	1.41e-05	3	76	2	28972185
Pubmed	Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.	CACNA1I CACNA1H	1.41e-05	3	76	2	11927664
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH6 KCNH2	1.41e-05	3	76	2	35818223
Pubmed	Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.	CACNA1I CACNA1H	1.41e-05	3	76	2	11897840
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH6 KCNH2	1.41e-05	3	76	2	12634931
Pubmed	Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.	GBF1 ARFGEF1	1.41e-05	3	76	2	18003980
Pubmed	The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).	GBF1 ARFGEF1	1.41e-05	3	76	2	23386609
Pubmed	Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling.	CHD1 CDH1	1.41e-05	3	76	2	19855082
Pubmed	A family of hyperpolarization-activated mammalian cation channels.	HCN3 HCN2	1.41e-05	3	76	2	9634236
Pubmed	Functional expression of the human HCN3 channel.	HCN3 HCN2	2.82e-05	4	76	2	16043489
Pubmed	Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.	HCN3 HCN2	2.82e-05	4	76	2	25042871
Pubmed	Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.	HCN3 HCN2	2.82e-05	4	76	2	26966193
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN3 HCN2	2.82e-05	4	76	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN3 HCN2	2.82e-05	4	76	2	12928435
Pubmed	Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.	CACNA1I CACNA1H	2.82e-05	4	76	2	28165634
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN3 HCN2	2.82e-05	4	76	2	21615589
Pubmed	The RANK/RANK ligand system is involved in interleukin-6 and interleukin-11 up-regulation by human myeloma cells in the bone marrow microenvironment.	IL11 TNFRSF11A	2.82e-05	4	76	2	15377473
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN3 HCN2	2.82e-05	4	76	2	20140458
Pubmed	The armadillo repeat region targets ARVCF to cadherin-based cellular junctions.	CDH1 CDH15	2.82e-05	4	76	2	11058098
Pubmed	mARVCF cellular localisation and binding to cadherins is influenced by the cellular context but not by alternative splicing.	CDH1 CDH15	2.82e-05	4	76	2	11719554
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN3 HCN2	2.82e-05	4	76	2	22748890
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN3 HCN2	2.82e-05	4	76	2	9630217
Pubmed	Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation.	PKD1 CDH1	2.82e-05	4	76	2	27179075
Pubmed	Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.	IL11 SLC27A1	2.82e-05	4	76	2	20360315
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN3 HCN2	4.69e-05	5	76	2	15564593
Pubmed	Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations.	CHD1 CDH1	4.69e-05	5	76	2	31883643
Pubmed	Polycystin: new aspects of structure, function, and regulation.	PKD1 CDH1	4.69e-05	5	76	2	11274246
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN3 HCN2	4.69e-05	5	76	2	34429357
Pubmed	Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons.	HCN3 HCN2	4.69e-05	5	76	2	30886335
Pubmed	The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species.	CDH1 CDH15	7.03e-05	6	76	2	1427864
Pubmed	Receptor protein tyrosine phosphatases are novel components of a polycystin complex.	PKD1 CDH1	7.03e-05	6	76	2	21126580
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	GBF1 TELO2 ARFGEF1 YME1L1	8.20e-05	104	76	4	31240132
Pubmed	Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.	HCN3 HCN2	9.83e-05	7	76	2	27956497
Pubmed	Elevated frequency of loss of heterozygosity in mammary tumors arising in mouse mammary tumor virus/neu transgenic mice.	CDH1 CDH15	9.83e-05	7	76	2	10344755
Pubmed	Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant.	PKD1 CDH1	9.83e-05	7	76	2	12095915
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN3 HCN2	9.83e-05	7	76	2	19421833
Pubmed	The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration.	CDH1 CDH15	9.83e-05	7	76	2	12052883
Pubmed	Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.	PKD1 CDH1	9.83e-05	7	76	2	24153433
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1I CACNA1H	1.31e-04	8	76	2	28330839
Pubmed	Severe acute respiratory syndrome coronavirus protein 6 mediates ubiquitin-dependent proteosomal degradation of N-Myc (and STAT) interactor.	FRY PKD1	1.31e-04	8	76	2	25907116
Pubmed	Notch1 and Jagged1 expression by the developing pulmonary vasculature.	CDH1 NOTCH4	1.31e-04	8	76	2	12242716
Pubmed	Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.	CACNA1I CACNA1H	1.31e-04	8	76	2	34478646
Pubmed	Intracellular calcium plays an essential role in cardiac development.	CACNA1I CACNA1H	1.31e-04	8	76	2	12761855
Pubmed	Notch signaling represses p63 expression in the developing surface ectoderm.	CDH1 NOTCH4	1.68e-04	9	76	2	23924630
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1I CACNA1H	1.68e-04	9	76	2	16382099
Pubmed	Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.	SHROOM1 CDH1	1.68e-04	9	76	2	17666436
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	HCN3 HCN2	2.10e-04	10	76	2	16382102
Pubmed	Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.	PKD1 CDH1	2.10e-04	10	76	2	11113628
Pubmed	Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.	CACNA1I CACNA1H	2.10e-04	10	76	2	24778262
Pubmed	Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.	KCNH6 KCNH2	2.10e-04	10	76	2	26503718
Pubmed	Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.	CDH1 NOTCH4	2.56e-04	11	76	2	16607638
Pubmed	Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.	CDH1 CDH15	3.62e-04	13	76	2	9615235
Pubmed	Genomic organization and chromosomal mapping of the mouse P-cadherin gene.	CDH1 CDH15	4.22e-04	14	76	2	1886768
Pubmed	Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero.	IL11 CDH1	4.22e-04	14	76	2	35803228
Pubmed	Cell-fate transition and determination analysis of mouse male germ cells throughout development.	CDH1 NOTCH4	4.22e-04	14	76	2	34824237
Pubmed	FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis.	TNFRSF11A CDH1	4.86e-04	15	76	2	31552487
Pubmed	ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding.	GBF1 ARFGEF1	4.86e-04	15	76	2	23572552
Pubmed	Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.	ARFGEF1 NCKAP1L	4.86e-04	15	76	2	16417406
Pubmed	Novel pancreas organogenesis markers refine the pancreatic differentiation roadmap of embryonic stem cells.	SCT CDH1	5.54e-04	16	76	2	24390927
Pubmed	Cadherin expression in the developing mouse olfactory system.	CDH1 CDH15	5.54e-04	16	76	2	17278136
Pubmed	Segmental expression of Notch and Hairy genes in nephrogenesis.	CDH1 NOTCH4	6.27e-04	17	76	2	15821257
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	GBF1 KMT2B KCNH2 PCNX4 PKD1 KBTBD11 GNA12 CACNA1H KIAA2013	6.75e-04	1105	76	9	35748872
Pubmed	WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development.	MYMX CDH15	7.05e-04	18	76	2	30389854
Pubmed	Genome-wide association study identifies three novel loci for type 2 diabetes.	C2CD4B DUSP9	7.87e-04	19	76	2	23945395
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	GBF1 ARFGEF1	7.87e-04	19	76	2	30674481
Pubmed	An Ideal PPAR Response Element Bound to and Activated by PPARα.	SLC27A1 CDH15	8.73e-04	20	76	2	26241474
Pubmed	E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.	CDH1 CDH15	8.73e-04	20	76	2	7806582
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	SNX4 SLC12A9 TELO2 ARFGEF1 YME1L1 KIAA2013 GP1BB SEMA4C	1.04e-03	942	76	8	31073040
Pubmed	Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation.	SCT CDH1	1.06e-03	22	76	2	17400205
Pubmed	Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.	CHD1 CDH1	1.16e-03	23	76	2	19841136
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SHROOM1 GBF1 CLASP1 TNIP2 CCDC88B	1.18e-03	361	76	5	26167880
Pubmed	Type II cadherins guide assembly of a direction-selective retinal circuit.	KCNG4 CDH1	1.26e-03	24	76	2	25126785
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GBF1 CLASP1 TELO2 TPTE2 DUSP9 CHD1 TIPRL YME1L1	1.29e-03	974	76	8	28675297
Pubmed	SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology.	CHD1 CDH1	1.37e-03	25	76	2	36343752
Pubmed	Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.	PKD1 CDH1	1.48e-03	26	76	2	37982452
Pubmed	Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.	KCNH6 KCNH2	1.48e-03	26	76	2	31138815
Pubmed	The transcription factor c-Maf controls touch receptor development and function.	KCNG4 CACNA1H	1.60e-03	27	76	2	22345400
Pubmed	Cdc42-mediated tubulogenesis controls cell specification.	CDH1 NOTCH4	1.72e-03	28	76	2	19914171
Interaction	KCNH4 interactions	KCNH6 KCNH2 ARFGEF1	1.02e-05	12	74	3	int:KCNH4
Interaction	GP9 interactions	KCNN4 GLB1L2 YME1L1 ENTPD4 GP1BB	2.35e-05	93	74	5	int:GP9
GeneFamily	Potassium voltage-gated channels	KCNH6 KCNG2 KCNH2 KCNG4	3.13e-06	40	46	4	274
GeneFamily	CD molecules\|Type I classical cadherins	CDH1 CDH15	6.30e-05	5	46	2	1185
GeneFamily	Cyclic nucleotide gated channels	HCN3 HCN2	2.81e-04	10	46	2	250
GeneFamily	Calcium voltage-gated channel subunits	CACNA1I CACNA1H	1.98e-03	26	46	2	253
ToppCell	COVID-19_Moderate-pDC\|World / disease group, cell group and cell class	KCNG2 OPN3 GAS6 SIDT1 SCT CDH1 MYMX NOTCH4	1.34e-09	191	76	8	93adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	2.34e-08	178	76	7	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	Healthy_donor-pDC\|Healthy_donor / disease group, cell group and cell class (v2)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.05e-08	185	76	7	7fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCell	ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, Lineage and Cell Type	KCNG2 OPN3 GAS6 SIDT1 SCT CDH1 NOTCH4	3.05e-08	185	76	7	7564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCell	Healthy_donor-pDC\|World / disease group, cell group and cell class (v2)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.29e-08	187	76	7	aa2cc54487d3c5045ac0c93560944c5a55878e27
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.41e-08	188	76	7	89411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.41e-08	188	76	7	de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.41e-08	188	76	7	879054b780378ae05be68e597c77c931bf0ade03
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.53e-08	189	76	7	209cae68d78c8f72479b169e27c3ff7e143adece
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.53e-08	189	76	7	6c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.53e-08	189	76	7	a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCell	COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease group, lineage and cell class	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.53e-08	189	76	7	c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX NOTCH4	3.53e-08	189	76	7	98ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	KCNG2 GAS6 SCT CDH1 MYMX NOTCH4	4.36e-07	168	76	6	cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	ENTPD7 KCNG2 GAS6 SCT CDH1 NOTCH4	4.68e-07	170	76	6	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	mild_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX	5.01e-07	172	76	6	dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCell	mild_COVID-19-pDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	KCNG2 OPN3 GAS6 SCT CDH1 MYMX	5.54e-07	175	76	6	b87f279a7519710146c49d6acccb0adedc195965
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENTPD7 KCNG2 GAS6 SIDT1 SCT NOTCH4	5.54e-07	175	76	6	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	mild-Myeloid-pDC\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	6.54e-07	180	76	6	38614155fa537d0defda914c531c697be0ef06d8
ToppCell	Healthy/Control-pDC\|World / Disease group and Cell class	OPN3 GAS6 SCT CDH1 MYMX NOTCH4	6.97e-07	182	76	6	97e0eee10905f2cf2bebb09e474629fc224f4397
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SCT CDH1 MYMX NOTCH4	7.67e-07	185	76	6	cc5152d3055375172bdf84f442b233c8fbd422b3
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SCT CDH1 MYMX NOTCH4	7.92e-07	186	76	6	a07694caf7fede06a47636725bcc7f09909cdf07
ToppCell	Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	OPN3 GAS6 SIDT1 SCT CDH1 NOTCH4	7.92e-07	186	76	6	330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCell	CF-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	ENTPD7 KCNG2 OPN3 GAS6 SCT CDH1	8.17e-07	187	76	6	adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCell	COVID-19_Severe-pDC\|World / disease group, cell group and cell class	OPN3 GAS6 SIDT1 SCT MYMX NOTCH4	8.43e-07	188	76	6	4c8e328b8206120708b05ea3c5865a0200dc5c4e
ToppCell	Control-Myeloid-pDC\|Control / Disease group, lineage and cell class	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.69e-07	189	76	6	46770b99da42f11f10cfc67cea8562342d60b867
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	adffa93635da10251f28b2089fd96b189775c8b4
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	9a91bf1ea105029e6412d0d9060bca325299ce26
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	39c8ddc2639bf3e986dae11fbae61a735614b604
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	2c1c079fd411c03bc3f383aa927eea9446716960
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	a95aea3aa707fc4574810706341a5f32b3d00209
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	8.96e-07	190	76	6	18dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCell	COVID-19_Severe-pDC\|COVID-19_Severe / disease group, cell group and cell class	OPN3 GAS6 SIDT1 SCT MYMX NOTCH4	8.96e-07	190	76	6	c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SIDT1 SCT MYMX NOTCH4	9.24e-07	191	76	6	8c487704cbbb5eeff54e8c6fb6fffa1472b5351f
ToppCell	COVID-19_Moderate-pDC\|COVID-19_Moderate / disease group, cell group and cell class	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	9.24e-07	191	76	6	9d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SIDT1 SCT MYMX NOTCH4	9.24e-07	191	76	6	78d523f562d32fc408a20d99b0c61cc103241bc0
ToppCell	Healthy-pDC\|World / disease group, cell group and cell class	KCNG2 OPN3 GAS6 SIDT1 SCT NOTCH4	9.24e-07	191	76	6	6e1d825dc33b915b95f13ccd237a552160a4be98
ToppCell	Healthy-pDC\|Healthy / disease group, cell group and cell class	KCNG2 OPN3 GAS6 SIDT1 SCT NOTCH4	9.53e-07	192	76	6	33d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCell	VE-pDC-\|VE / Condition, Cell_class and T cell subcluster	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	9.82e-07	193	76	6	583724de588fcde3aeda056138c522dc0225a387
ToppCell	control-pDC\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	OPN3 GAS6 SIDT1 SCT CDH1 NOTCH4	9.82e-07	193	76	6	30a6559c9a9e8941861cb259b4836acccc427e68
ToppCell	VE-pDC\|VE / Condition, Cell_class and T cell subcluster	KCNG2 OPN3 GAS6 SCT MYMX NOTCH4	9.82e-07	193	76	6	bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCell	MS-Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	KCNG2 OPN3 GAS6 SIDT1 CDH1 NOTCH4	1.17e-06	199	76	6	c10c8c9322cad4996e4aa11a8680e3d781644ace
ToppCell	Sepsis-ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, condition lineage and cell class	KCNG2 OPN3 GAS6 SIDT1 CDH1 NOTCH4	1.17e-06	199	76	6	a199e67438eeed903d0996605591ec54400fdd66
ToppCell	COVID-19-COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease, condition lineage and cell class	KCNG2 OPN3 GAS6 SIDT1 CDH1 NOTCH4	1.17e-06	199	76	6	9de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell	356C-Myeloid-Dendritic-pDC\|356C / Donor, Lineage, Cell class and subclass (all cells)	KCNG2 OPN3 GAS6 SIDT1 SCT	7.12e-06	156	76	5	d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC12A9 OPN3 SLC27A1 FBXO33 NCKAP1L	9.35e-06	165	76	5	354978d4f35154d7b2e36e94de669e045adef512
ToppCell	Influenza_Severe-pDC\|World / Disease group and Cell class	KCNG2 OPN3 GAS6 SCT NOTCH4	9.62e-06	166	76	5	bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCell	severe-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	OPN3 GAS6 SIDT1 SCT NOTCH4	9.62e-06	166	76	5	ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	KCNG2 OPN3 SIDT1 SCT GNA12	9.91e-06	167	76	5	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|World / disease group, cell group and cell class (v2)	KCNG2 GAS6 SCT TNFRSF11A MYMX	9.91e-06	167	76	5	bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCell	NS-moderate-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KCNG2 OPN3 GAS6 SIDT1 SCT	1.02e-05	168	76	5	d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	KCNG2 GAS6 SCT TNFRSF11A MYMX	1.02e-05	168	76	5	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	Healthy_Control-Lymphoid-pDC\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ENTPD7 KCNG2 SIDT1 SCT GLB1L2	1.05e-05	169	76	5	a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCell	Healthy_Control-Lymphoid-pDC-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ENTPD7 KCNG2 SIDT1 SCT GLB1L2	1.05e-05	169	76	5	338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell	severe_influenza-pDC\|World / disease group, cell group and cell class (v2)	OPN3 GAS6 SCT MYMX NOTCH4	1.08e-05	170	76	5	b9c08af83241666bbdbed9109cadcd088c0f647d
ToppCell	facs-Heart-LV-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF6 C2CD4B KBTBD11 CACNA1I CDH1	1.11e-05	171	76	5	c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCell	facs-Heart-LV-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF6 C2CD4B KBTBD11 CACNA1I CDH1	1.11e-05	171	76	5	55b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 SLC27A1 DUSP9 CDH1 SEMA4C	1.14e-05	172	76	5	30916a902c151907745756d14327e24adc34afef
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR10 SLAMF6 SIDT1 KBTBD11 KCNN4	1.14e-05	172	76	5	30f4979abf0218618a56afb06aa6afc23ad838ec
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B SLAMF6 SIDT1 KBTBD11 KCNN4	1.21e-05	174	76	5	fedadde222df1952d6456f4f3413c01579146e1f
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B SLAMF6 SIDT1 KBTBD11 KCNN4	1.21e-05	174	76	5	e69a011ae9698368923223d3af3243e609c08c83
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENTPD7 KCNG2 SIDT1 SCT NOTCH4	1.21e-05	174	76	5	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	IIF-Myeloid-pDC\|IIF / Disease, Lineage and Cell Type	GAS6 SIDT1 SCT CDH1 NOTCH4	1.24e-05	175	76	5	35cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLAMF6 DUSP9 SIDT1 KBTBD11 KCNN4	1.24e-05	175	76	5	e7b0eda141b638f1aad9938aaa76b1ce80171be9
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KCNG2 OPN3 GAS6 SIDT1 SCT	1.24e-05	175	76	5	97fe431f224b592b3076632d101e19136c138dcc
ToppCell	CF-Lymphoid-pDC\|CF / Disease state, Lineage and Cell class	KCNG2 OPN3 GAS6 SIDT1 SCT	1.28e-05	176	76	5	dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCell	ILEUM-inflamed-(3)_pDC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ENTPD7 KCNG2 OPN3 GAS6 CDH1	1.28e-05	176	76	5	b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBM12B OPN3 HCN3 GNA12 TNFRSF11A	1.31e-05	177	76	5	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B SLAMF6 SIDT1 KBTBD11 KCNN4	1.31e-05	177	76	5	9d2d70d53b919fed3328812889a55e5e1a0759de
ToppCell	facs-Heart-LA-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF6 SIDT1 KBTBD11 KCNN4 NMUR1	1.35e-05	178	76	5	b4b4e021e86d1d523fa40695cb0a91021dee27d1
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	ENTPD7 KCNG2 SIDT1 SCT NOTCH4	1.35e-05	178	76	5	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 SLC27A1 DUSP9 CDH1 SEMA4C	1.39e-05	179	76	5	1757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNG2 OPN3 SIDT1 SCT MYMX	1.39e-05	179	76	5	bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ENTPD7 KCNG2 SIDT1 SCT NOTCH4	1.39e-05	179	76	5	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 SLC27A1 DUSP9 CDH1 SEMA4C	1.39e-05	179	76	5	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ENTPD7 KCNG2 SIDT1 SCT NOTCH4	1.42e-05	180	76	5	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KCNG2 OPN3 GAS6 SIDT1 SCT	1.42e-05	180	76	5	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KCNG2 OPN3 GAS6 SIDT1 SCT	1.42e-05	180	76	5	144818e69613296cde43f29cb8c20899c670b319
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KCNG2 OPN3 GAS6 SIDT1 SCT	1.42e-05	180	76	5	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GAS6 SCT CDH1 MYMX NOTCH4	1.50e-05	182	76	5	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GAS6 SCT CDH1 MYMX NOTCH4	1.50e-05	182	76	5	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GAS6 NPDC1 PTGIS NOTCH4 INKA1	1.54e-05	183	76	5	ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C2CD4B GAS6 NPDC1 PTGIS NOTCH4	1.58e-05	184	76	5	16ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	KCNG2 OPN3 GAS6 SCT NOTCH4	1.58e-05	184	76	5	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	Bac-SEP-Myeloid-pDC\|Bac-SEP / Disease, Lineage and Cell Type	OPN3 GAS6 SIDT1 SCT NOTCH4	1.62e-05	185	76	5	3de50b2042f22b0fb62ff12c76d85cc67649a0bd
ToppCell	normal-na-Myeloid-plasmacytoid_dendritic_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SCT MYMX NOTCH4	1.62e-05	185	76	5	3091870a5bf8ecb963e560b47c8502bae367416c
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	31df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCell	facs-Marrow-KLS-24m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM250 KCNN4 NPDC1 INKA1 GP1BB	1.67e-05	186	76	5	f14722ecc832794dc267bf3f9b8a13274c3addc1
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	b95be984e308d4f9061274a35995ec558d434e74
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	8f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	95c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	b70cd94c651b56dcf2e55554533a5f1130845390
ToppCell	COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease group, lineage and cell class	OPN3 GAS6 SCT MYMX NOTCH4	1.67e-05	186	76	5	3db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAD2 C2CD4B SIDT1 NPDC1 NOTCH4	1.71e-05	187	76	5	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	OPN3 GAS6 SIDT1 SCT NOTCH4	1.71e-05	187	76	5	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	COVID-19_Severe-pDC-\|COVID-19_Severe / Disease condition and Cell class	OPN3 GAS6 SIDT1 SCT MYMX	1.75e-05	188	76	5	9fd1116e31a05554850b8ed3c005ea660dfbd51c
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	OPN3 GAS6 SCT MYMX NOTCH4	1.75e-05	188	76	5	26405ef1b934744e672c642db78834c21d3ba28f
ToppCell	COVID-19_Mild-pDC\|COVID-19_Mild / Disease condition and Cell class	OPN3 GAS6 SIDT1 SCT MYMX	1.75e-05	188	76	5	62d33d2990d4a2d32bd0863147e47f656df1966e
ToppCell	COVID-19_Mild-pDC-\|COVID-19_Mild / Disease condition and Cell class	OPN3 GAS6 SIDT1 SCT MYMX	1.75e-05	188	76	5	a75c2cf2f8dae343c13aaa66b637658b935ed10a
Drug	HCNs	HCN3 CACNA1I CACNA1H HCN2	4.79e-07	20	74	4	CID006857665
Drug	verapamil	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 PKD1 KCNN4 CACNA1I CACNA1H YME1L1 ABCA10	5.05e-07	490	74	11	CID000002520
Drug	pyraclofos	KCNH6 KCNG2 KCNH2 KCNG4 CACNA1I CACNA1H	1.27e-06	106	74	6	CID000093460
Drug	Miconazole	KCNH6 KCNH2 KCNN4	1.82e-06	8	74	3	DB01110
Drug	ZD7288	CACNA1I CACNA1H HCN2	3.89e-06	10	74	3	CID000123983
Drug	diazoxide	KCNH6 KCNG2 KCNH2 KCNG4 HCN3 KCNN4 YME1L1	9.11e-06	227	74	7	CID000003019
Drug	Mibefradil	KCNH2 CACNA1I CACNA1H	9.21e-06	13	74	3	ctd:D020748
Drug	N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine	KCNH6 KCNH2	1.04e-05	2	74	2	ctd:C531033
Drug	potassium	KCNH6 KCNG2 SLC12A9 KCNH2 KCNG4 HCN3 PKD1 KCNN4 SCT CACNA1I CACNA1H HCN2 YME1L1	1.98e-05	1008	74	13	CID000000813
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A_EA	TELO2 OPN3 PCNX4 KCNN4 CTDSP1 SEMA4C	2.35e-05	176	74	6	1011_DN
Drug	SureCN2398996	CACNA1I CACNA1H	3.12e-05	3	74	2	CID010220069
Drug	N-desmethylmethsuximide	CACNA1I CACNA1H	3.12e-05	3	74	2	CID000092154
Drug	1,3-dioxoisoindoline-5-carboxamide	CACNA1I CACNA1H	3.12e-05	3	74	2	CID010679219
Drug	zatebradine	KCNH2 HCN2	3.12e-05	3	74	2	ctd:C043636
Drug	Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A	ENTPD7 DSCAM SLC12A9 KCNH2 CDH1 SEMA4C	3.94e-05	193	74	6	4118_DN
Drug	Lymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A	IL11 FRY GAS6 CACNA1H PTGIS ENTPD4	4.42e-05	197	74	6	3514_UP
Drug	S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ENTPD7 DSCAM SLC12A9 ACADSB KCNH2 CACNA1I	4.54e-05	198	74	6	6473_DN
Drug	compound 30	KCNH2 CACNA1I CACNA1H	4.85e-05	22	74	3	CID005492232
Drug	mibefradil	PKD1 KCNN4 CACNA1I CACNA1H	5.64e-05	64	74	4	CID000060662
Drug	pimozide	KCNH6 KCNH2 PKD1 CACNA1I CACNA1H	5.91e-05	127	74	5	CID000016362
Drug	methsuximide	CACNA1I CACNA1H	6.23e-05	4	74	2	CID000006476
Drug	Amiodarone	KCNH2 CACNA1H	6.23e-05	4	74	2	DB01118
Drug	NS1643	KCNH6 KCNH2	6.23e-05	4	74	2	CID010177784
Drug	CAS 298-57-7	PKD1 CACNA1I CACNA1H PTGIS	9.44e-05	73	74	4	CID000002761
Drug	clofilium	KCNH6 KCNH2 KCNN4 HCN2	9.96e-05	74	74	4	CID000002798
Drug	AC1O7G5C	CACNA1I CACNA1H	1.04e-04	5	74	2	CID006603942
Drug	phensuximide	CACNA1I CACNA1H	1.04e-04	5	74	2	CID000006839
Drug	Flunarizine	CACNA1I CACNA1H	1.04e-04	5	74	2	DB04841
Drug	tetraethylammonium	KCNG2 NRXN2 KCNH2 PKD1 KCNN4 YME1L1	1.20e-04	236	74	6	CID000005413
Drug	jasplakinolide	CACNA1H HCN2 CDH1	1.39e-04	31	74	3	ctd:C057531
Drug	AC1MQ5W8	CACNA1I CACNA1H	1.55e-04	6	74	2	CID003396482
Drug	Doxazosin	KCNH6 KCNH2	1.55e-04	6	74	2	DB00590
Drug	cerebrocrast	CACNA1I CACNA1H	1.55e-04	6	74	2	CID000159556
Drug	Prazosin	KCNH6 KCNH2	1.55e-04	6	74	2	DB00457
Drug	Terazosin	KCNH6 KCNH2	1.55e-04	6	74	2	DB01162
Drug	3,4-dihydroquinazoline	CACNA1I CACNA1H	1.55e-04	6	74	2	CID000583065
Drug	CNS 1145	PKD1 CACNA1I CACNA1H	1.68e-04	33	74	3	CID000190902
Drug	IHC-64	PKD1 CACNA1I CACNA1H	1.68e-04	33	74	3	CID000162753
Disease	short QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	1.86e-05	3	74	2	DOID:0050793 (implicated_via_orthology)
Disease	rheumatoid arthritis	SLAMF6 KMT2B TELO2 TNFRSF11A CCDC88B NOTCH4 GP1BB	1.61e-04	462	74	7	EFO_0000685
Disease	long QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	2.76e-04	10	74	2	DOID:2843 (implicated_via_orthology)
Disease	Nonorganic psychosis	KCNH6 KCNH2 GNA12	7.04e-04	69	74	3	C0349204
Disease	caudal middle frontal gyrus volume measurement	FRY PCNX4	9.25e-04	18	74	2	EFO_0010290
Disease	Agouti-related protein measurement	CDH1 CDH15	2.09e-03	27	74	2	EFO_0008016
Disease	Psychotic Disorders	KCNH6 KCNH2 GNA12	2.12e-03	101	74	3	C0033975
Disease	lysophosphatidylethanolamine 20:4 measurement	CACNA1I FBXO33	2.41e-03	29	74	2	EFO_0010370
Disease	heart conduction disease (implicated_via_orthology)	KCNH6 KCNH2	2.93e-03	32	74	2	DOID:10273 (implicated_via_orthology)
Disease	prostate cancer (implicated_via_orthology)	P4HA3 CHD1	3.12e-03	33	74	2	DOID:10283 (implicated_via_orthology)
Disease	age of onset of Alzheimer disease	DSCAM DPEP3	3.12e-03	33	74	2	OBA_2001000
Disease	Autistic Disorder	NRXN2 ACADSB SCT CACNA1H	4.24e-03	261	74	4	C0004352

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVIARRALLRFLFRQ	ADAD2	286	Q8NCV1
AFLGLRFRQDLRRLL	CCR10	311	P46092
LRTLERENRELRGLL	CCDC88B	461	A6NC98
KLRRERRALLCLLLV	ABCA10	766	Q8WWZ4
IPELRAVLRRFFLRI	ARFGEF1	1816	Q9Y6D6
VRLLRGSRLLRRNFL	ACADSB	6	P45954
ILLDKLLIRLRERGN	CHD1	791	O14646
LLIRLRERGNRVLIF	CHD1	796	O14646
NRRRFLGTEVLLRLI	RBM12B	461	Q8IXT5
LAPERRLLGLLRRYL	P4HA3	41	Q7Z4N8
LLGLSEQLRRRLARA	INKA1	226	Q96EL1
VLGLGALRRRKRLLE	KCNN4	6	O15554
YLLIGLRLRRERLLL	NMUR1	251	Q9HB89
VLLAIFLYLLRLRRI	ENTPD7	561	Q9NQZ7
KVGLVLRVLRALRIL	KCNG4	331	Q8TDN1
IGLLKTARLLRLVRV	KCNH2	521	Q12809
LIGLLKTARLLRLVR	KCNH6	371	Q9H252
GTRRLRLRLLRAESL	C2CD4B	261	A6NLJ0
RLQQLRRLRGLLRVL	FBXO33	31	Q7Z6M2
LLLVLLLCRLRRLRA	GP1BB	166	P13224
LGTLQARLDRLLRRL	IL11	126	P20809
GLRLLLVGIIRDRLI	PCNX4	521	Q63HM2
LGEVRARLLRALRLV	PDCD7	171	Q8N8D1
ERAGLVLRLLRALRV	KCNG2	281	Q9UJ96
RQYLLPLLRRLARRL	MYMX	26	A0A1B0GTQ4
VRRGLLVLRLAERAA	PEAK3	426	Q6ZS72
DLSRLGRDLRRVLIL	CTDSP1	191	Q9GZU7
DFLELLLVDGRLRLR	NRXN2	76	Q9P2S2
LRRLRRGSLSVRALL	DUSP9	51	Q99956
ELLFLLEGIRSLVRR	NCKAP1L	406	P55160
RQLLRLLRQDLGLER	LRRC75B	51	Q2VPJ9
ALLRLLGLRRGLRRL	KMT2B	66	Q9UMN6
LSLLRLLRLSRLIRY	HCN3	216	Q9P1Z3
RHLRLLRLLLSGLVL	NPDC1	11	Q9NQX5
FRRSLLQLLCLRLLR	OPN3	316	Q9H1Y3
IVLALRAGRLELQLR	GAS6	346	Q14393
KILGVLRVLRLLRTL	CACNA1I	1266	Q9P0X4
RRAVRRLVKILLLGA	GNA12	51	Q03113
VGLLRLAIRLLRREE	GBF1	1201	Q92538
LRRRPARTLGLLLLV	GLB1L2	6	Q8IW92
LLLLVVLGFLVLRRL	GLB1L2	16	Q8IW92
RDLLRLQLLRIFELL	FRY	1026	Q5TBA9
ALSRRYLRRLLLLLL	DPEP3	11	Q9H4B8
ILGVLRVLRLLRTLR	CACNA1H	1391	O95180
VILFRLLGVILFRLL	C9orf57	31	Q5W0N0
ELSRLREGARLQRLL	SCT	36	P09683
LLLVLVLLVALRARF	CDH15	616	P55291
ILSLLRLLRLSRLIR	HCN2	331	Q9UL51
LILILLLLLFLRRRA	CDH1	721	P12830
ALLRFRRLLVAELQR	PKD1	3241	P98161
VLLLFVLLLVVRRRR	DSCAM	1606	O60469
VERRRIGLENFLLRI	SNX4	151	O95219
LLLLGVLAARAARRR	SIGLEC15	276	Q6ZMC9
IILLLLVLRKRRDSL	SLAMF6	241	Q96DU3
AALLLLLLLSRRRTR	PTGIS	11	Q16647
RLLRRLLDGVAGRVL	IQCA1L	71	A6NCM1
LAILLYLLRLRRIHR	ENTPD4	576	Q9Y227
LLLLGSRLARVRRAL	SHROOM1	716	Q2M3G4
ARLLARFLREGRLAV	TELO2	121	Q9Y4R8
LLVLSLRRRLREELE	SEMA4C	681	Q9C0C4
ALGALLVLQLIRRRR	NOTCH4	1461	Q99466
LSGAERDLLLRRRLR	KBTBD11	276	O94819
SIRALALRVLREILR	CLASP1	1361	Q7Z460
RDALIARLRARLAAL	TNIP2	41	Q8NFZ5
IGLIRLLRREIAAVF	MRPL10	76	Q7Z7H8
FGLSVLIRVRLELRR	SLC27A1	56	Q6PCB7
QRKLSVLLLLLGRRR	TMEM250	91	H0YL14
VLLLLLGRRRVDFRL	TMEM250	96	H0YL14
LGRRRVDFRLVNELL	TMEM250	101	H0YL14
LLLRFFLRIDGVLIR	TIPRL	181	O75663
LLGFLFLLIVLRRDI	SIDT1	506	Q9NXL6
AEGRLRALLSQLRIR	SLC12A9	781	Q9BXP2
DLLLVALIKGLVRRR	PLPP6	176	Q8IY26
RRTRLILFVLLLFGI	YME1L1	291	Q96TA2
EALGEQALRRRRLLL	TMEM245	136	Q9H330
QALRRRRLLLLLGAG	TMEM245	141	Q9H330
VRLLRLIILIRIFHL	TPTE2	176	Q6XPS3
RRVVLASFLLLLLGL	TMEM134	121	Q9H6X4
RRRRPLFALLLLCAL	TNFRSF11A	6	Q9Y6Q6
VLLLREGLLRRVRCL	KIAA2013	141	Q8IYS2
KFLLRLLRGRLEVDL	NALCN	1491	Q8IZF0