Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-9 ERVK-8 ERVK-19 ERVK-25	2.00e-06	37	113	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-9 ERVK-8 ERVK-19 ERVK-25	2.30e-06	38	113	5	GO:0070001
GeneOntologyMolecularFunction	ATP hydrolysis activity	MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 HSPA2 VCP	4.14e-05	441	113	11	GO:0016887
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RAP2A ARL13A MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 RAP2C HSPA2 VCP	1.22e-04	775	113	14	GO:0017111
GeneOntologyMolecularFunction	indanol dehydrogenase activity	AKR1B10 AKR1B15	1.89e-04	4	113	2	GO:0047718
GeneOntologyMolecularFunction	allyl-alcohol dehydrogenase activity	AKR1B10 AKR1B15	1.89e-04	4	113	2	GO:0047655
GeneOntologyMolecularFunction	pyrophosphatase activity	RAP2A ARL13A MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 RAP2C HSPA2 VCP	2.77e-04	839	113	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RAP2A ARL13A MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 RAP2C HSPA2 VCP	2.80e-04	840	113	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RAP2A ARL13A MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 RAP2C HSPA2 VCP	2.80e-04	840	113	14	GO:0016818
GeneOntologyMolecularFunction	geranylgeranyl reductase activity	AKR1B10 AKR1B15	4.69e-04	6	113	2	GO:0045550
GeneOntologyMolecularFunction	ATP-dependent activity	MSH2 KATNA1 ATAD2 ATP10A DNAH12 DDX50 MACF1 ATP1A2 ATP1A4 HSPA2 VCP	7.25e-04	614	113	11	GO:0140657
GeneOntologyMolecularFunction	histone H3K9 monomethyltransferase activity	SETDB1 PRDM16	8.69e-04	8	113	2	GO:0140948
GeneOntologyMolecularFunction	NADP+ binding	AKR1B10 AKR1B15	1.11e-03	9	113	2	GO:0070401
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A2 ATP1A4	1.39e-03	10	113	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A2 ATP1A4	1.39e-03	10	113	2	GO:0005391
GeneOntologyMolecularFunction	histone H3K9me2 methyltransferase activity	SETDB1 PRDM16	1.39e-03	10	113	2	GO:0140947
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8	1.69e-03	11	113	2	GO:0004523
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A2 ATP1A4	1.69e-03	11	113	2	GO:0008556
Domain	TAU_MAP_1	MAP2 MAP4	9.72e-05	3	107	2	PS00229
Domain	TAU_MAP_2	MAP2 MAP4	9.72e-05	3	107	2	PS51491
Domain	Tubulin-binding	MAP2 MAP4	9.72e-05	3	107	2	PF00418
Domain	MAP_tubulin-bd_rpt	MAP2 MAP4	9.72e-05	3	107	2	IPR001084
Domain	MAP2/MAP4/Tau	MAP2 MAP4	9.72e-05	3	107	2	IPR027324
Domain	ARM-type_fold	USP34 UBR4 RICTOR URB1 MROH1 EIF2B5 LTN1 SERAC1 STAG3	1.45e-04	339	107	9	IPR016024
Domain	Actinin_actin-bd_CS	DST SYNE2 MACF1	2.98e-04	23	107	3	IPR001589
Domain	Spectrin	DST SYNE2 MACF1	2.98e-04	23	107	3	PF00435
Domain	ACTININ_2	DST SYNE2 MACF1	2.98e-04	23	107	3	PS00020
Domain	ACTININ_1	DST SYNE2 MACF1	2.98e-04	23	107	3	PS00019
Domain	-	DST MACF1	4.80e-04	6	107	2	3.90.1290.10
Domain	GAR	DST MACF1	4.80e-04	6	107	2	PS51460
Domain	-	DST MACF1	4.80e-04	6	107	2	3.30.920.20
Domain	P-type_ATPase_IIC	ATP1A2 ATP1A4	4.80e-04	6	107	2	IPR005775
Domain	GAS_dom	DST MACF1	4.80e-04	6	107	2	IPR003108
Domain	GAS2	DST MACF1	4.80e-04	6	107	2	PF02187
Domain	GAS2	DST MACF1	4.80e-04	6	107	2	SM00243
Domain	CH	IQGAP2 DST SYNE2 MACF1	5.27e-04	65	107	4	SM00033
Domain	ATPase_AAA_CS	KATNA1 ATAD2 VCP	5.99e-04	29	107	3	IPR003960
Domain	Spectrin_repeat	DST SYNE2 MACF1	5.99e-04	29	107	3	IPR002017
Domain	Plectin_repeat	DST MACF1	6.70e-04	7	107	2	IPR001101
Domain	Plectin	DST MACF1	6.70e-04	7	107	2	PF00681
Domain	PLEC	DST MACF1	6.70e-04	7	107	2	SM00250
Domain	CH	IQGAP2 DST SYNE2 MACF1	6.98e-04	70	107	4	PF00307
Domain	-	IQGAP2 DST SYNE2 MACF1	7.37e-04	71	107	4	1.10.418.10
Domain	Spectrin/alpha-actinin	DST SYNE2 MACF1	8.03e-04	32	107	3	IPR018159
Domain	-	ATP10A ATP1A2 ATP1A4	8.03e-04	32	107	3	3.40.1110.10
Domain	-	ATP10A ATP1A2 ATP1A4	8.03e-04	32	107	3	2.70.150.10
Domain	SPEC	DST SYNE2 MACF1	8.03e-04	32	107	3	SM00150
Domain	CH	IQGAP2 DST SYNE2 MACF1	8.18e-04	73	107	4	PS50021
Domain	Vps4_C	KATNA1 VCP	8.90e-04	8	107	2	PF09336
Domain	Vps4_C	KATNA1 VCP	8.90e-04	8	107	2	IPR015415
Domain	CH-domain	IQGAP2 DST SYNE2 MACF1	9.05e-04	75	107	4	IPR001715
Domain	ARM-like	RICTOR ATAD2 MROH1 LTN1 SERAC1 STAG3 ARMH4	9.31e-04	270	107	7	IPR011989
Domain	AAA	KATNA1 ATAD2 VCP	9.61e-04	34	107	3	PS00674
Domain	ATPase_P-typ_cyto_domN	ATP10A ATP1A2 ATP1A4	1.05e-03	35	107	3	IPR023299
Domain	P_typ_ATPase	ATP10A ATP1A2 ATP1A4	1.14e-03	36	107	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP10A ATP1A2 ATP1A4	1.14e-03	36	107	3	IPR018303
Domain	ATPASE_E1_E2	ATP10A ATP1A2 ATP1A4	1.14e-03	36	107	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP10A ATP1A2 ATP1A4	1.23e-03	37	107	3	IPR008250
Domain	E1-E2_ATPase	ATP10A ATP1A2 ATP1A4	1.23e-03	37	107	3	PF00122
Domain	ALDOKETO_REDUCTASE_1	AKR1B10 AKR1B15	1.42e-03	10	107	2	PS00798
Domain	Aldo/ket_reductase_CS	AKR1B10 AKR1B15	1.42e-03	10	107	2	IPR018170
Domain	Aldo/keto_reductase	AKR1B10 AKR1B15	1.42e-03	10	107	2	IPR020471
Domain	ALDOKETO_REDUCTASE_2	AKR1B10 AKR1B15	1.42e-03	10	107	2	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1B10 AKR1B15	1.42e-03	10	107	2	PS00063
Domain	SET	SMYD4 SETDB1 PRDM16	2.32e-03	46	107	3	SM00317
Domain	SET_dom	SMYD4 SETDB1 PRDM16	2.95e-03	50	107	3	IPR001214
Domain	SET	SMYD4 SETDB1 PRDM16	2.95e-03	50	107	3	PS50280
Domain	AAA	KATNA1 ATAD2 VCP	3.30e-03	52	107	3	PF00004
Domain	ATPase_AAA_core	KATNA1 ATAD2 VCP	3.67e-03	54	107	3	IPR003959
Domain	-	ATP1A2 ATP1A4	3.70e-03	16	107	2	1.20.1110.10
Domain	-	AKR1B10 AKR1B15	3.70e-03	16	107	2	3.20.20.100
Domain	ATPase_P-typ_TM_dom	ATP1A2 ATP1A4	3.70e-03	16	107	2	IPR023298
Domain	NADP_OxRdtase_dom	AKR1B10 AKR1B15	4.18e-03	17	107	2	IPR023210
Domain	ATPase_P-typ_cation-transptr_C	ATP1A2 ATP1A4	4.18e-03	17	107	2	IPR006068
Domain	Cation_ATPase_C	ATP1A2 ATP1A4	4.18e-03	17	107	2	PF00689
Domain	Aldo_ket_red	AKR1B10 AKR1B15	4.18e-03	17	107	2	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1B10 AKR1B15	4.18e-03	17	107	2	IPR001395
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	4.69e-03	18	107	2	PF00690
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	4.69e-03	18	107	2	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP1A2 ATP1A4	5.22e-03	19	107	2	IPR004014
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP34 NFASC LRIG2 DST AKAP9 LTN1 MACF1 ATP1A2	1.75e-09	101	115	8	9872452
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-9 ERVK-8 ERVK-19	5.50e-08	12	115	4	14557543
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 NFASC MED13L DSCAML1 URB1 DST SYNE2 MACF1 PRDM16	6.57e-08	225	115	9	12168954
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	CUL2 IQGAP2 MAP2 MAP4 UBR4 MSH2 EDC4 CHAMP1 DST SYNE2 MACF1 FYN	1.06e-07	498	115	12	36634849
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 MAP4 UBR4 MSH2 EDC4 ATAD2 URB1 DST SYNE2 MACF1 HSPA2 VCL VCP	2.71e-07	653	115	13	22586326
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	6.99e-07	6	115	3	15063128
Pubmed	Maternal diabetes alters transcriptional programs in the developing embryo.	HIF1A MAP2 SEMA3A VCL	3.80e-06	32	115	4	19538749
Pubmed	Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.	SETDB1 EIF2B5 MACF1 VCL	6.16e-06	36	115	4	16097034
Pubmed	[Expression and clinical significance of hypoxia-inducible factor-1alpha and angiopoietin-2 in laryngeal squamous cell carcinoma].	HIF1A ANGPT2	1.08e-05	2	115	2	18727515
Pubmed	Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse.	AKR1B10 AKR1B15	1.08e-05	2	115	2	34954342
Pubmed	Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.	AKR1B10 AKR1B15	1.08e-05	2	115	2	25120755
Pubmed	Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.	AKR1B10 AKR1B15	1.08e-05	2	115	2	21087085
Pubmed	Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.	AKR1B10 AKR1B15	1.08e-05	2	115	2	8526877
Pubmed	AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.	AKR1B10 AKR1B15	1.08e-05	2	115	2	36518763
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.08e-05	2	115	2	11002341
Pubmed	HIF1α-dependent upregulation of ATAD2 promotes proliferation and migration of stomach cancer cells in response to hypoxia.	HIF1A ATAD2	1.08e-05	2	115	2	31959473
Pubmed	Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn.	HIF1A ANGPT2	1.08e-05	2	115	2	11801735
Pubmed	Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.	AKR1B10 AKR1B15	1.08e-05	2	115	2	33644071
Pubmed	PRDM16 suppresses HIF-targeted gene expression in kidney cancer.	HIF1A PRDM16	1.08e-05	2	115	2	32251515
Pubmed	Functional expression of novel human and murine AKR1B genes.	AKR1B10 AKR1B15	1.08e-05	2	115	2	21276782
Pubmed	Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.	AKR1B10 AKR1B15	1.08e-05	2	115	2	31911858
Pubmed	FBXO30 functions as a tumor suppressor and an E3 ubiquitin ligase for hZIP1‑mediated HIF‑1α degradation in renal cell carcinoma.	HIF1A FBXO30	1.08e-05	2	115	2	36799168
Pubmed	Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.	HIF1A SEMA3A	1.08e-05	2	115	2	31929360
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.08e-05	2	115	2	9060628
Pubmed	Effect of chronic intermittent hypoxia-induced HIF-1α/ATAD2 expression on lung cancer stemness.	HIF1A ATAD2	1.08e-05	2	115	2	35672694
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.08e-05	2	115	2	9460924
Pubmed	The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.	ATP1A2 ATP1A4	1.08e-05	2	115	2	10555956
Pubmed	Interphase and monoastral-mitotic phenotypes of overexpressed MAP4 are modulated by free tubulin concentrations.	MAP2 MAP4	1.08e-05	2	115	2	12890753
Pubmed	1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.	AKR1B10 AKR1B15	1.08e-05	2	115	2	7578036
Pubmed	Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.	AKR1B10 AKR1B15	1.08e-05	2	115	2	8541228
Pubmed	Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1 alpha.	HIF1A ANGPT2	1.08e-05	2	115	2	16629644
Pubmed	Developmental study of the distribution of hypoxia-induced factor-1 alpha and microtubule-associated protein 2 in children's brainstem: comparison between controls and cases with signs of perinatal hypoxia.	HIF1A MAP2	1.08e-05	2	115	2	24780770
Pubmed	Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers.	CUL2 HIF1A	1.08e-05	2	115	2	20078552
Pubmed	Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.	HIF1A SEMA3A	1.08e-05	2	115	2	32012286
Pubmed	The human testis-enriched HSPA2 interacts with HIF-1α in epidermal keratinocytes, yet HIF-1α stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity.	HIF1A HSPA2	1.08e-05	2	115	2	38641179
Pubmed	Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.	HIF1A IRAK3	1.08e-05	2	115	2	25746953
Pubmed	Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.	AKR1B10 AKR1B15	1.08e-05	2	115	2	25538260
Pubmed	Disruption of the actin network enhances MAP-2c and Fyn-induced process outgrowth.	MAP2 FYN	1.08e-05	2	115	2	16145685
Pubmed	SEMA3A and IGSF10 Are Novel Contributors to Combined Pituitary Hormone Deficiency (CPHD).	SEMA3A IGSF10	1.08e-05	2	115	2	32612575
Pubmed	Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan.	ANK3 NFASC	1.08e-05	2	115	2	29963618
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-9 ERVK-8 ERVK-19 ERVK-25	1.57e-05	94	115	5	21542922
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANK3 FOXP2 IQGAP2 UBR4 NFASC EDC4 LRIG2 HOOK3 DST AKAP9 SYNE2 MACF1 QSER1	1.88e-05	963	115	13	28671696
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CUL2 USP34 IQGAP2 UBR4 MSH2 EDC4 URB1 HOOK3 DST DDX50 SYNE2 EIF2B5 LTN1 ZNF740 HSPA2 VCP	2.16e-05	1440	115	16	30833792
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	HIF1A FOXP2 DSCAML1 SEMA3A SYNE2 MACF1 TAF1 FYN	2.65e-05	358	115	8	32460013
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ANK3 MAP4 UBR4 KATNA1 ATP10A SYCP2 DDX50 MACF1	2.81e-05	361	115	8	26167880
Pubmed	MicroRNA-574-3p Regulates HIF-α Isoforms Promoting Gastric Cancer Epithelial-Mesenchymal Transition via Targeting CUL2.	CUL2 HIF1A	3.24e-05	3	115	2	34655362
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	3.24e-05	3	115	2	12399109
Pubmed	Hypoxia-Inducible Factor-1α in SM22α-Expressing Cells Modulates Alveolarization.	HIF1A ANGPT2	3.24e-05	3	115	2	37290124
Pubmed	Post-translational control of beige fat biogenesis by PRDM16 stabilization.	CUL2 PRDM16	3.24e-05	3	115	2	35978186
Pubmed	Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.	CUL2 HIF1A	3.24e-05	3	115	2	25326537
Pubmed	Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.	AKR1B10 AKR1B15	3.24e-05	3	115	2	17381426
Pubmed	Correlation between semaphorin3A-induced facilitation of axonal transport and local activation of a translation initiation factor eukaryotic translation initiation factor 4E.	SEMA3A FYN	3.24e-05	3	115	2	15240808
Pubmed	Notch signaling mediates hypoxia-induced tumor cell migration and invasion.	HIF1A MAML1	3.24e-05	3	115	2	18427106
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	3.24e-05	3	115	2	9971820
Pubmed	Binding of Fyn to MAP-2c through an SH3 binding domain. Regulation of the interaction by ERK2.	MAP2 FYN	3.24e-05	3	115	2	11546790
Pubmed	Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.	MAP2 FYN	3.24e-05	3	115	2	31452242
Pubmed	A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase.	AKR1B10 AKR1B15	3.24e-05	3	115	2	7510692
Pubmed	Effect of hindlimb unweighting on expression of hypoxia-inducible factor-1alpha vascular endothelial growth factor, angiopoietin, and their receptors in mouse skeletal muscle.	HIF1A ANGPT2	3.24e-05	3	115	2	17705680
Pubmed	Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.	HIF1A RICTOR	3.24e-05	3	115	2	29425506
Pubmed	SEMA3A signaling controls layer-specific interneuron branching in the cerebellum.	SEMA3A FYN	3.24e-05	3	115	2	23602477
Pubmed	Vinculin knockout results in heart and brain defects during embryonic development.	MAP2 VCL	3.24e-05	3	115	2	9486805
Pubmed	Fyn phosphorylates human MAP-2c on tyrosine 67.	MAP2 FYN	3.24e-05	3	115	2	15536091
Pubmed	Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma.	HIF1A ANGPT2	3.24e-05	3	115	2	25100134
Pubmed	MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2.	HIF1A ANGPT2	3.24e-05	3	115	2	35163556
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	3.24e-05	3	115	2	10516026
Pubmed	Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer.	HIF1A ANGPT2	3.24e-05	3	115	2	16338068
Pubmed	Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology.	MAP2 MAP4	3.24e-05	3	115	2	37258650
Pubmed	miR-582 negatively regulates pre-B cell proliferation and survival through targeting Hif1α and Rictor.	HIF1A RICTOR	3.24e-05	3	115	2	35115499
Pubmed	Angiopoietin-2 Promotes Mechanical Stress-induced Extracellular Matrix Degradation in Annulus Fibrosus Via the HIF-1α/NF-κB Signaling Pathway.	HIF1A ANGPT2	3.24e-05	3	115	2	37475697
Pubmed	Noncentrosomal microtubules and type II myosins potentiate epidermal cell adhesion and barrier formation.	MAP2 MAP4	3.24e-05	3	115	2	23091070
Pubmed	Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells.	HIF1A HSPA2	3.24e-05	3	115	2	26164067
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CUL2 UBR4 CDC45 SMYD4 SETDB1 DST ARHGAP29 MACF1 VCP	3.31e-05	481	115	9	28190767
Pubmed	QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.	ANK3 DST AKAP9	3.85e-05	20	115	3	33397958
Pubmed	Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury.	HIF1A ANGPT2 VCL	3.85e-05	20	115	3	21270129
Pubmed	UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.	CUL2 HIF1A UBR4 VCP	5.46e-05	62	115	4	18775313
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MAP4 EDC4 CREB5 URB1 ATP1A2 HSPA2	5.93e-05	202	115	6	24639526
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL2 FRAS1 RICTOR CDC45 SMYD4 DST EIF2B5 PAM QSER1 MICU2	6.23e-05	650	115	10	38777146
Pubmed	Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.	RAP2A RAP2C	6.48e-05	4	115	2	16540189
Pubmed	Renal cell carcinoma risk in type 2 von Hippel-Lindau disease correlates with defects in pVHL stability and HIF-1alpha interactions.	CUL2 HIF1A	6.48e-05	4	115	2	16261165
Pubmed	Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.	SEMA3A FYN	6.48e-05	4	115	2	16540575
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A2 ATP1A4	6.48e-05	4	115	2	21849490
Pubmed	Dynamic HIF1A regulation during human placental development.	CUL2 HIF1A	6.48e-05	4	115	2	16611863
Pubmed	Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics.	MAP2 MAP4	6.48e-05	4	115	2	8631898
Pubmed	ZER1 Contributes to the Carcinogenic Activity of High-Risk HPV E7 Proteins.	CUL2 UBR4	6.48e-05	4	115	2	36346242
Pubmed	The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1.	HIF1A ANGPT2	6.48e-05	4	115	2	18720385
Pubmed	Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.	AKR1B10 AKR1B15	6.48e-05	4	115	2	21179467
Pubmed	Humanized Foxp2 specifically affects cortico-basal ganglia circuits.	FOXP2 MAP2	6.48e-05	4	115	2	21111790
Pubmed	Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments.	ANK3 NFASC	6.48e-05	4	115	2	11724816
Pubmed	PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector.	RAP2A ARHGAP29	6.48e-05	4	115	2	15752761
Pubmed	Brain microvasculature and hypoxia-related proteins in Alzheimer's disease.	HIF1A ANGPT2	6.48e-05	4	115	2	21904637
Pubmed	Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.	CUL2 HIF1A	6.48e-05	4	115	2	11865071
Pubmed	Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.	MAP2 MAP4	6.48e-05	4	115	2	10542369
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	6.48e-05	4	115	2	8954775
Pubmed	Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.	IQGAP2 VCP	6.48e-05	4	115	2	28970065
Pubmed	The protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.	MAP2 FYN	6.48e-05	4	115	2	22403409
Pubmed	Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex.	SEMA3A FYN	6.48e-05	4	115	2	12372285
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-19	6.48e-05	4	115	2	7983737
Pubmed	Role of exon 2-encoded beta -domain of the von Hippel-Lindau tumor suppressor protein.	CUL2 HIF1A	6.48e-05	4	115	2	11024059
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 MED13L ADCY2 SETDB1 AKAP9 MROH1 PACS2 MACF1	6.53e-05	407	115	8	12693553
Pubmed	Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes.	CUL2 HIF1A CDC45	6.78e-05	24	115	3	34195792
Interaction	FBXO30 interactions	HIF1A RICTOR FBXO30 SETDB1 VCL	1.29e-05	56	109	5	int:FBXO30
Interaction	FTCD interactions	USP34 HIF1A DST HSPA2	1.73e-05	29	109	4	int:FTCD
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A2 ATP1A4	3.61e-04	7	76	2	1208
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	4.80e-04	8	76	2	939
GeneFamily	AAA ATPases	KATNA1 ATAD2 VCP	1.44e-03	53	76	3	413
GeneFamily	Aldo-keto reductases	AKR1B10 AKR1B15	1.77e-03	15	76	2	399
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CUL2 USP34 HIF1A MSH2 MED13L CREB5 SETDB1 DST AKAP9 SYNE2 LTN1 ARHGAP29 MACF1 MICU2 FYN VCL	4.48e-07	856	108	16	M4500
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN	CLCA4 HIF1A COPZ2 STON1 AKR1B10 ARHGAP29 TMEM184B TMEM100	1.83e-06	200	108	8	M3450
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	IQGAP2 NFASC ATP10A DST PAM MACF1 FYN ARMH4	2.83e-06	212	108	8	M39221
Coexpression	LIAO_HAVE_SOX4_BINDING_SITES	MAP4 HSPBAP1 AKR1B10 PAM	2.45e-05	41	108	4	M15025
Coexpression	IKEDA_MIR133_TARGETS_UP	HIF1A MAML1 AKAP9 RAP2C	3.26e-05	44	108	4	M2377
Coexpression	IKEDA_MIR133_TARGETS_UP	HIF1A MAML1 AKAP9 RAP2C	3.57e-05	45	108	4	MM929
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	IQGAP2 MAP2 MUC16 ZC3H12B ATAD2 ADCY2 SEMA3A IGSF10 AKR1B10 SYNE2 LTN1 PWWP3B FYN ARMH4	2.83e-05	768	106	14	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	COPZ2 STON1 IQGAP2 MUC16 ZC3H12B ADCY2 SEMA3A IGSF10 KCNJ3 AKR1B10 SYNE2 LTN1 PWWP3B ARMH4	3.04e-05	773	106	14	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	FRAS1 COPZ2 IQGAP2 MAP2 MUC16 ZC3H12B ADCY2 SEMA3A IGSF10 KCNJ3 AKR1B10 LTN1 QSER1 ARMH4	3.21e-05	777	106	14	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_500	FOXP2 ATAD2 ADCY2 SEMA3A HOOK3	5.67e-05	82	106	5	gudmap_developingKidney_e15.5_Peripheral blastema_500_k3
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#2_top-relative-expression-ranked_500	MAP2 SEMA3A LRIG2 ARHGAP29 PAM	8.39e-05	89	106	5	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k2_500
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 MAP2 DSCAML1 CREB5 DST SULT1C2 SYNE2 VCL CACNA2D3	1.08e-09	189	110	9	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 MAP2 DSCAML1 CREB5 DST SULT1C2 SYNE2 VCL CACNA2D3	1.08e-09	189	110	9	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP4 HOOK3 DST AKAP9 PAM MACF1 FYN TMEM100	2.47e-08	190	110	8	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 FOXP2 DSCAML1 SULT1C2 KCNJ3 PRDM16 CACNA2D3	3.03e-08	195	110	8	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 MAP2 NFASC ATP10A FYN SLC4A11 ARMH4	3.67e-07	183	110	7	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN SLC4A11 ARMH4	3.95e-07	185	110	7	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 ANK3 DSCAML1 SULT1C2 KCNJ3 SYNE2 CACNA2D3	4.25e-07	187	110	7	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 FOXP2 SULT1C2 KCNJ3 PRDM16 CACNA2D3	5.44e-07	194	110	7	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 FOXP2 SULT1C2 KCNJ3 PRDM16 CACNA2D3	5.83e-07	196	110	7	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	T_cells-CTLs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RAP2A IQGAP2 SYNE2 MACF1 FYN PRDM16 VCL	6.03e-07	197	110	7	2de34e20915a247bee75aa40495e23c20bb23e18
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 DST SULT1C2 SYNE2 ARHGAP29 MACF1 TMEM100	6.67e-07	200	110	7	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ZC3H12B ATP10A SYNE2 ARHGAP29 PAM ATP1A2 FYN	6.67e-07	200	110	7	7136936d05ab344a560cf159684c881063b5430d
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ANK3 NFASC RICTOR SYNE2 MACF1 FYN	2.51e-06	156	110	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FOXP2 ADCY2 DSCAML1 SEMA3A CACNA2D3	2.91e-06	160	110	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FOXP2 ADCY2 DSCAML1 SEMA3A CACNA2D3	2.91e-06	160	110	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	3.85e-06	168	110	6	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	3.85e-06	168	110	6	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANK3 MAP2 MSH2 CDC45 SYCP2 SLC4A11	4.26e-06	171	110	6	b113fbebb89056af0b9c775d2fb6552206a80467
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	4.41e-06	172	110	6	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 FOXP2 MUC16 ADCY2 FER1L6 SYCP2	4.71e-06	174	110	6	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 IGSF10 KCNJ3 PAM MACF1 ATP1A2	5.03e-06	176	110	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 MUC16 FER1L6 URB1 MACF1 SLC4A11	5.54e-06	179	110	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	FOXP2 MUC16 ADCY2 FER1L6 SYCP2 SLC4A11	5.54e-06	179	110	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	5.54e-06	179	110	6	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 FOXP2 MAGI3 DSCAML1 PRDM16 CACNA2D3	5.54e-06	179	110	6	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	5.91e-06	181	110	6	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	5.91e-06	181	110	6	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 FOXP2 MAGI3 SYNE2 PRDM16 CACNA2D3	6.49e-06	184	110	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ATP10A DSCAML1 CREB5 DST PAM MACF1	6.49e-06	184	110	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ANK3 MAP4 DST PAM ATP1A2 VCL	6.49e-06	184	110	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	6.70e-06	185	110	6	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A DST FYN ARMH4	6.70e-06	185	110	6	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FOXP2 IQGAP2 MAP2 DSCAML1 ATP1A2 PRDM16	6.90e-06	186	110	6	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FOXP2 DSCAML1 SYNE2 ARHGAP29 CACNA2D3	6.90e-06	186	110	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIF1A FOXP2 DSCAML1 SYNE2 ARHGAP29 CACNA2D3	7.12e-06	187	110	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 FOXP2 MAGI3 SYNE2 PRDM16 CACNA2D3	7.12e-06	187	110	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 DSCAML1 SYNE2 ARHGAP29 VCL CACNA2D3	7.34e-06	188	110	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 DSCAML1 KCNJ3 SYNE2 ARHGAP29 SLC4A11	7.57e-06	189	110	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 FOXP2 MAGI3 KCNJ3 PRDM16 CACNA2D3	7.57e-06	189	110	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP2A ANGPT2 ANK3 TMEM100 HSPA2 VCL	7.57e-06	189	110	6	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 DSCAML1 SYNE2 ARHGAP29 SLC4A11 CACNA2D3	8.03e-06	191	110	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	ANGPT2 MAP2 NFASC ATP1A2 PRDM16 HSPA2	8.03e-06	191	110	6	2da83c493e60ad0278848957645277d76737a188
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIF1A MAP2 ATP10A CREB5 MACF1 FYN	8.28e-06	192	110	6	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRAS1 ANK3 LRIG2 AKAP9 SYNE2 MACF1	8.53e-06	193	110	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 DSCAML1 CREB5 SYNE2 ARHGAP29 CACNA2D3	8.78e-06	194	110	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 CREB5 SULT1C2 SYNE2 ARHGAP29	8.78e-06	194	110	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 ANK3 MAGI3 SYNE2 PWWP3B PRDM16	9.04e-06	195	110	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MUC16 MAGI3 ADCY2 FER1L6 SLC4A11	9.04e-06	195	110	6	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 FOXP2 MAGI3 KCNJ3 PRDM16	9.31e-06	196	110	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 FOXP2 SULT1C2 KCNJ3 CACNA2D3	9.31e-06	196	110	6	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 FRAS1 ANK3 AKAP9 SYNE2 MACF1	9.58e-06	197	110	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	ANGPT2 MAP2 NFASC ATP1A2 PRDM16 HSPA2	9.86e-06	198	110	6	89986c7756541df364df516329d10775ba0e78a4
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 ANK3 RICTOR AKAP9 SYNE2 MACF1	1.01e-05	199	110	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FRAS1 MAGI3 DSCAML1 SYNE2 SLC4A11 CACNA2D3	1.01e-05	199	110	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 DST SYNE2 ARHGAP29 MACF1 TMEM100	1.04e-05	200	110	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 DST SYNE2 ARHGAP29 MACF1 FYN	1.04e-05	200	110	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 IQGAP2 MUC16 ADCY2 SYCP2 SLC4A11	1.04e-05	200	110	6	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 DST SYNE2 ARHGAP29 MACF1 TMEM100	1.04e-05	200	110	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 ANKUB1 DSCAML1 ARHGAP29 CACNA2D3	2.83e-05	143	110	5	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANKUB1 C1orf87 MUC16 DNAH12 SYNE2	4.29e-05	156	110	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	6.10e-05	168	110	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ANGPT2 ANK3 ADCY2 URB1 SYNE2	6.27e-05	169	110	5	bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CLCA4 MAP2 CREB5 DST HSPA2	6.82e-05	172	110	5	bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CLCA4 MAP2 CREB5 DST HSPA2	6.82e-05	172	110	5	aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	6.82e-05	172	110	5	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 ANK3 FOXP2 MAGI3 PRDM16	7.01e-05	173	110	5	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	7.20e-05	174	110	5	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGSL1 MAP2 ADCY2 DSCAML1 ATP1A2	7.40e-05	175	110	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	FRAS1 ANK3 CREB5 KCNJ3 CACNA2D3	7.60e-05	176	110	5	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	COVID-19-Myeloid-MoAM4\|COVID-19 / Condition, Lineage and Cell class	RAP2A DSCAML1 DST ATP1A4 CACNA2D3	7.81e-05	177	110	5	ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	7.81e-05	177	110	5	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MAGI3 DSCAML1 PRDM16 CACNA2D3	7.81e-05	177	110	5	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 CREB5 SULT1C2 PRDM16 CACNA2D3	8.02e-05	178	110	5	dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	8.02e-05	178	110	5	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DSCAML1 SULT1C2 SYNE2 ARHGAP29 SLC4A11	8.02e-05	178	110	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 SEMA3A DST ARHGAP29 MACF1	8.02e-05	178	110	5	ad3de3e03a401dac64431a541899445262246347
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK3 FOXP2 SYNE2 PRDM16 CACNA2D3	8.23e-05	179	110	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|metastatic_Brain / Location, Cell class and cell subclass	ANGPT2 HSPBAP1 USP51 ARHGAP29 TMEM100	8.23e-05	179	110	5	56fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4 IGSF10 PAM MACF1 FYN	8.45e-05	180	110	5	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4 IGSF10 PAM MACF1 FYN	8.45e-05	180	110	5	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 IQGAP2 SYNE2 FYN FSBP	8.45e-05	180	110	5	d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell	severe-CD8+_T_naive\|World / disease stage, cell group and cell class	RGSL1 ANK3 SETDB1 ZNF852 PACS2	8.67e-05	181	110	5	69eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MAGI3 DSCAML1 PRDM16 CACNA2D3	8.67e-05	181	110	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FOXP2 DSCAML1 ARHGAP29 CACNA2D3	8.67e-05	181	110	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 IQGAP2 KCNJ3 PRDM16	8.67e-05	181	110	5	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FOXP2 DSCAML1 ARHGAP29 CACNA2D3	8.90e-05	182	110	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 DSCAML1 SULT1C2 KCNJ3 CACNA2D3	8.90e-05	182	110	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 CREB5 SEMA3A DST ARHGAP29	9.13e-05	183	110	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	IQGAP2 NFASC ATP10A FYN ARMH4	9.13e-05	183	110	5	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	9.13e-05	183	110	5	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	9.13e-05	183	110	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	MUC16 ADCY2 FER1L6 SYCP2 SLC4A11	9.13e-05	183	110	5	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	9.13e-05	183	110	5	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 NFASC ATP10A FYN ARMH4	9.13e-05	183	110	5	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 IQGAP2 KCNJ3 PRDM16	9.13e-05	183	110	5	b5ede5a0048c585b73c00e88aeddbcaf669347b1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	AKAP9 SYNE2 MACF1 FYN	1.44e-04	49	59	4	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	ATAD2 DST SYNE2 MACF1	1.56e-04	50	59	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Computational	Genes in the cancer module 372.	FOXP2 MSH2 ATAD2	2.93e-04	24	59	3	MODULE_372
Disease	neuroblastoma, cutaneous melanoma	STON1 MAGI3 FYN	1.46e-04	28	108	3	EFO_0000389, EFO_0000621
Disease	parenchymal hematoma, response to recombinant tissue-plasminogen activator	DSCAML1 SEMA3A	1.97e-04	6	108	2	EFO_0020101, EFO_0600080
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A2 ATP1A4	2.75e-04	7	108	2	DOID:0060178 (implicated_via_orthology)
Disease	symmetrical dimethylarginine measurement	AKR1B10 AKR1B15	4.70e-04	9	108	2	EFO_0006523
Disease	schizophrenia (is_marker_for)	ANK3 MAP2 SETDB1	5.66e-04	44	108	3	DOID:5419 (is_marker_for)
Disease	hippocampal volume	MAP2 MED13L KATNA1 DSCAML1 AKAP9 PAM	8.01e-04	297	108	6	EFO_0005035
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK3 SYNE2	8.55e-04	12	108	2	DOID:11726 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	ATP1A2 ATP1A4	8.55e-04	12	108	2	DOID:863 (implicated_via_orthology)
Disease	Migraine Disorders	ATP1A2 PRDM16	1.01e-03	13	108	2	C0149931
Disease	cutaneous melanoma	STON1 MED13L SYNE2 FYN	1.04e-03	121	108	4	EFO_0000389
Disease	Schizophrenia	ANK3 FOXP2 NFASC SEMA3A CBLIF SETDB1 SLC26A8 KCNJ3 ERVK-8 FYN	1.51e-03	883	108	10	C0036341
Disease	diabetic retinopathy (implicated_via_orthology)	HIF1A ANGPT2	1.54e-03	16	108	2	DOID:8947 (implicated_via_orthology)
Disease	cutaneous melanoma, hair color	MED13L ATP10A SYNE2	1.54e-03	62	108	3	EFO_0000389, EFO_0003924
Disease	macrophage inflammatory protein 1b measurement	CLCA4 ANK3 MAP4 ZNF852	1.60e-03	136	108	4	EFO_0008219
Disease	response to phenylephrine	IQGAP2 ATP10A	1.74e-03	17	108	2	EFO_0010152
Disease	Bipolar Disorder	HIF1A ANK3 MAP2 ADCY2 CBLIF ATP1A2 FYN	1.89e-03	477	108	7	C0005586
Disease	lung cancer (is_implicated_in)	RICTOR MSH2 SETDB1	2.56e-03	74	108	3	DOID:1324 (is_implicated_in)
Disease	schizophrenia (is_implicated_in)	ANK3 FOXP2 FYN	2.97e-03	78	108	3	DOID:5419 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	NFASC KCNA10 ATP1A2 ATP1A4	3.08e-03	163	108	4	DOID:1826 (implicated_via_orthology)
Disease	frailty measurement	ANK3 FOXP2	3.19e-03	23	108	2	EFO_0009885
Disease	electrocardiography	STON1 PAM ATP1A2 MICU2 FYN PRDM16 VCL	3.40e-03	530	108	7	EFO_0004327
Disease	Anhedonia	ANK3 SETDB1	3.48e-03	24	108	2	C0178417

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTEFTTGMILPTKAM	AHSA2P	156	Q719I0
APLTHKMNKMVTSEE	ERVK-25	21	P61579
SKIMVEDKVSFENMT	AKAP9	1046	Q99996
EVFTKKMIESMSRPS	CCDC117	191	Q8IWD4
APLTHKMNKMVTSEE	ERVK-19	21	O71037
APLTHKMNKMVTSEE	ERVK-8	21	Q902F8
APLTHKMNKMVTSEE	ERVK-9	21	Q9UKH3
FPKSKVTDIMDVVTM	CXorf58	166	Q96LI9
PSSESTKTTKMVEAM	ADGRG4	346	Q8IZF6
TMEVTEMSPSKNSFI	ADGRG4	1271	Q8IZF6
KNKMVSSAFTTEMIE	ADGRG4	1621	Q8IZF6
SSFTPTSLMEDMKVS	ARMH4	396	Q86TY3
DTFPSMKEQMVFEKN	COPZ2	66	Q9P299
MMSTSNSAKDPTVAK	ANGPT2	261	O15123
MATFVELSTKAKMPI	AKR1B10	1	O60218
TKMENKPTSSELQKM	PAM	836	P19021
SKKNMSVTFALDEPM	ARL13A	256	Q5H913
AKDFEVAMQKMIPAS	ATAD2	676	Q6PL18
MLSKHTAFSSPMEKD	ATP10A	516	O60312
SLKTETQTMHQKPMT	C1orf87	41	Q8N0U7
APLTHKMNKMVTSEE	HERVK_113	21	P61574
APLTHKMNKMVTSEE	HERV-K104	21	P61576
APLTHKMNKMVTSEE	ERVK-19	21	P61572
APLTHKMNKMVTSEE	ERVK-6	21	Q69383
APLTHKMNKMVTSEE	ERVK-9	21	P61573
PFMETSAKSKTMVDE	RAP2A	141	P10114
PFMETSAKSKSMVDE	RAP2C	141	Q9Y3L5
DMTSEVLQITMSPDK	RAD1	171	O60671
SEVMKMDLSESSKPL	QSER1	791	Q2KHR3
SETKPKLMTPDAFMT	EDC4	586	Q6P2E9
DVTTKLKAMQEFGTM	LTN1	76	O94822
EMTLKFPSIKTDNML	CREB5	41	Q02930
KQDFTNSKLLMMPSV	MAML1	456	Q92585
EMSTTLKIMSSKEPS	MUC16	3201	Q8WXI7
VKTTDMLNTSMEPVT	MUC16	4491	Q8WXI7
LFTSPIMTKSAEMTV	MUC16	5551	Q8WXI7
SMPRSSAMKKIESET	MUC16	6346	Q8WXI7
EMMDSFQFLVKDSKP	FRAS1	2526	Q86XX4
PMVSMVSTQLTEFKM	MED13L	901	Q71F56
KTTDMAPSKETEMAL	MAP4	246	P27816
MVEKSLPSKMTNKTT	MAGI3	1361	Q5TCQ9
AMNEKVKKFMETTDP	DST	4216	Q03001
LKPVESSDMKMTQLF	HIF1A	361	Q16665
SSDMKMTQLFTKVES	HIF1A	366	Q16665
KNVSVMTMIFKESSP	EIF2B5	176	Q13144
FPEEISSMVLTKMKE	HSPA2	116	P54652
KPLNLVSSVTMSKNM	FOXP2	421	O15409
TSMAKMHIFQPEISK	DNAH12	2271	Q6ZR08
MEIEQSVKSFKMPSS	KCT2	176	Q8NC54
PTGTMKMSVDEFQKV	LRRC74A	436	Q0VAA2
MTQKTPFECSQSEVM	IRAK3	501	Q9Y616
ATPTMSMTVVTKEKN	PACS2	796	Q86VP3
MTAIQELMSKESPVS	HOOK3	151	Q86VS8
AAQMEDKKPFILSSM	MROH1	381	Q8NDA8
TLMNMAASFDIPKEK	RICTOR	451	Q6R327
EVLKSMDAMSSPTKT	MACF1	4486	Q9UPN3
MDAMSSPTKTETVKA	MACF1	4491	Q9UPN3
NMSKTVLSQTMFTDP	KCNA10	256	Q16322
MSSSMEPITQDKRVS	NFASC	176	O94856
EQNSLTAKTTMIMPS	ARHGAP29	1086	Q52LW3
TAKTTMIMPSALQEK	ARHGAP29	1091	Q52LW3
MGMKSMSTVPQFETT	HSPBAP1	76	Q96EW2
MTTENGKISTTDVPM	ADCY2	516	Q08462
KSSKIMDSFKNMVPQ	ATP1A2	151	P50993
VVFATMSLMESPEKD	CDC45	376	O75419
KTTAMSKNINPTMSS	IGSF10	866	Q6WRI0
PLKFMMSKNTSVPVS	ICE2	346	Q659A1
QRKNPMFKFETTMTS	CBLIF	351	P27352
APLTHKMNKMVTSEE	ERVK-25	21	P61570
APLTHKMNKMVTSEE	ERVK-6	21	Q69384
MTTVAMPVFSKQNET	CACNA2D3	476	Q8IZS8
DISKSMFLTVKIPAM	DSCAML1	776	Q8TD84
SKENKMDMTSPEQSR	CHAMP1	666	Q96JM3
MSPESFLEEAQIMKK	FYN	306	P06241
TANPKVTFKMSEIMI	DPP8	336	Q6V1X1
FKITTSMQKDTPQEM	CUL2	651	Q13617
VPSTMDLVKSKSMDA	DDX50	516	Q9BQ39
TTVTEKHKMNVPETM	ANK3	826	Q12955
KQRTEMSSKAMPDSF	ANK3	2811	Q12955
KMLKNTKPMTTFQEE	C17orf80	121	Q9BSJ5
PTTMEDFEMALKKVS	KATNA1	456	O75449
APLTHKMNKMVTSEE	HERVK_113	21	Q902F9
MMDPFQVEKVKQSTD	CCDC168	976	Q8NDH2
MMSKATDKVSKPREQ	FBXO30	141	Q8TB52
EFLSKVKQMPFTEMS	MSH2	886	P43246
TSVVPKMLMNFLSEK	OR1L8	76	Q8NGR8
STMAPKMIFDLLTEK	OR4C5	96	Q8NGB2
PKMNSSIMANVTKAF	FER1L6	256	Q2WGJ9
MEKCTKSSSTMQVEP	RTL4	1	Q6ZR62
PKASGTMFTEKMTTT	RTL9	621	Q8NET4
QMPSLKMASSKETRI	RGSL1	291	A5PLK6
PKMKSTKTAMEVART	SLC4A11	241	Q8NBS3
KMLLEASTKPEMSTV	SERAC1	506	Q96JX3
MKMQEKDSLTESFPA	SMYD4	196	Q8IYR2
QPSTEKAMEPTMKFS	SYNE2	1076	Q8WXH0
KAMEPTMKFSLASVL	SYNE2	1081	Q8WXH0
APMKSISSSLKETMN	TMEM184B	331	Q9Y519
DAREPMAVTSQTKKM	PWWP3B	521	Q5H9M0
ITMMAPVESKFSQST	TAF1	311	P21675
MEPKAETETKTQTEM	SLC26A8	886	Q96RN1
MPQNKSTKFMDTVIF	IQGAP2	906	Q13576
FTSTTVPKMIVDMQT	OR7E24	91	Q6IFN5
PQMSAIETMTEKLES	PRDM16	896	Q9HAZ2
FSVMFEQMERKTSVK	MICU2	111	Q8IYU8
SKTKEMSNSMTPSQK	SEMA3A	686	Q14563
TGQPFDTMKVKMQTF	SLC25A15	26	Q9Y619
TMTKQEADDMSIPIS	URB1	731	O60287
EPMFSMKTSSASALE	SETDB1	396	Q15047
MATFVELSTKAKMPI	AKR1B15	1	C9JRZ8
TVMVDGFTKPKMTSK	ANKUB1	346	A6NFN9
KSSKIMESFKNMVPQ	ATP1A4	161	Q13733
FPDKVQTEKASIMFM	CLCA4	226	Q14CN2
MTPFLASTKESRMKE	USP51	621	Q70EK9
MFSSRNKEMPIDQKS	STON1	206	Q9Y6Q2
IVTPEMFKKMSNSEI	STAG3	146	Q9UJ98
TEMDGMSTKKNVFII	VCP	606	P55072
QETSFEKMKENPMTN	SULT1C2	226	O00338
EKMKENPMTNRSTVS	SULT1C2	231	O00338
MEEPTSSTNENKMKS	SPANXN4	1	Q5MJ08
TPSKRKMSEASMIVS	SYCP2	471	Q9BX26
TKKVMEMIPQISSFC	FSBP	101	O95073
SKTISPMVMDAKAVA	VCL	791	P18206
SLKMTPFRASLTKME	nan	26	Q9UF83
APLTHKMNKMVTSEE	ERVK-8	21	P61575
HMAATMEKSPKSEVV	TMEM100	16	Q9NV29
MTATAEVETPKMEKS	ZC3H12B	1	Q5HYM0
AMTSKTLEKAMTEPS	MAP2	511	P11137
EDRMPMNVKSVTKHS	ZNF844	581	Q08AG5
MMESSELTPKQEIFK	ZNF852	51	Q6ZMS4
MTMPASKKSTVKAEI	ZNF454	86	Q8N9F8
MASSAKSAEMPTISK	SPZ1	1	Q9BXG8
VTMMKEKVNTHFSFP	USP34	2096	Q70CQ2
SLVPTAASKKMMLSQ	ZNF740	16	Q8NDX6
FTAMMKSAKLPQTVK	UBR4	151	Q5T4S7
MSSTMKESAFQSEPR	UBR4	1736	Q5T4S7
LVSKTTKMLSDPMSQ	KCNJ3	451	P48549
TMKPFTANMQSDIKV	BPIFA4P	121	Q86YQ2
DQTLSSLMVQMPKET	LRIG2	931	O94898