Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionthiolester hydrolase activity

ACOT4 PLA2G6 ACOT1 ACOT6 ABHD17B

1.56e-04472185GO:0016790
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

ACOT4 PLA2G6 ACOT1 ACOT6

1.99e-04272184GO:0047617
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ACOT4 PLA2G6 ACOT1 ACOT6

2.30e-04282184GO:0016289
GeneOntologyMolecularFunctionDNA-dependent protein kinase activity

PRKDC ATM

3.53e-0432182GO:0004677
GeneOntologyMolecularFunctionhistone H2AXS139 kinase activity

PRKDC ATM

3.53e-0432182GO:0035979
DomainARM-type_fold

WAPL TRRAP DNAAF5 PIK3C2G NCAPD2 MROH7 PKP1 AP1G2 HECTD1 UNC79 AP3D1 HEATR4 TOGARAM2 WDFY4 THADA PPP2R5B PRKDC ATM WDFY3

1.29e-0833921319IPR016024
DomainFAT

TRRAP TMTC1 PRKDC ATM

2.42e-0762134PF02259
DomainPIK-rel_kinase_FAT

TRRAP TMTC1 PRKDC ATM

2.42e-0762134IPR003151
Domain-

TRRAP DNAAF5 NCAPD2 MROH7 PKP1 AP1G2 HECTD1 AP3D1 HEATR4 TOGARAM2 WDFY4 PRKDC WDFY3

1.69e-06222213131.25.10.10
DomainARM-like

TRRAP DNAAF5 NCAPD2 MROH7 PKP1 AP1G2 HECTD1 AP3D1 HEATR4 TOGARAM2 WDFY4 PRKDC WDFY3

1.42e-0527021313IPR011989
DomainBAAT_C

ACOT4 ACOT1 ACOT6

1.44e-0552133IPR014940
DomainBAAT_C

ACOT4 ACOT1 ACOT6

1.44e-0552133PF08840
Domain-

TRRAP PIK3C2G PRKDC ATM

2.69e-051621341.10.1070.11
DomainPI3Kc

TRRAP PIK3C2G PRKDC ATM

2.69e-05162134SM00146
DomainFAT

TRRAP PRKDC ATM

2.85e-0562133PS51189
DomainFATC

TRRAP PRKDC ATM

2.85e-0562133PS51190
DomainFATC_dom

TRRAP PRKDC ATM

2.85e-0562133IPR003152
DomainLiprin

PPFIA4 PPFIA2 PPFIA1

2.85e-0562133IPR029515
DomainPIK_FAT

TRRAP PRKDC ATM

2.85e-0562133IPR014009
DomainFATC

TRRAP PRKDC ATM

2.85e-0562133SM01343
DomainPI3_PI4_kinase

TRRAP PIK3C2G PRKDC ATM

4.44e-05182134PF00454
DomainPI3_4_KINASE_1

TRRAP PIK3C2G PRKDC ATM

4.44e-05182134PS00915
DomainPI3_4_KINASE_2

TRRAP PIK3C2G PRKDC ATM

4.44e-05182134PS00916
DomainPI3/4_kinase_cat_dom

TRRAP PIK3C2G PRKDC ATM

4.44e-05182134IPR000403
DomainPI3_4_KINASE_3

TRRAP PIK3C2G PRKDC ATM

4.44e-05182134PS50290
DomainWD40

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

1.98e-0425921311PF00400
DomainWD40

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

2.66e-0426821311SM00320
DomainOA_transporter

SLCO1B3 SLCO5A1 SLCO4C1

2.98e-04122133IPR004156
DomainOATP

SLCO1B3 SLCO5A1 SLCO4C1

2.98e-04122133PF03137
DomainWD40_repeat

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

3.02e-0427221311IPR001680
DomainWD_REPEATS_1

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

3.63e-0427821311PS00678
DomainWD_REPEATS_2

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

3.74e-0427921311PS50082
DomainWD_REPEATS_REGION

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

3.74e-0427921311PS50294
DomainDP

TFDP3 TFDP1

3.85e-0432132PF08781
DomainLatrophilin

ADGRL3 ADGRL1

3.85e-0432132PF02354
DomainVav

VAV3 VAV1

3.85e-0432132IPR028530
DomainTranscrpt_fac_DP

TFDP3 TFDP1

3.85e-0432132IPR015648
DomainTransc_factor_DP_C

TFDP3 TFDP1

3.85e-0432132IPR014889
DomainTalin-1

TLN2 TLNRD1

3.85e-0432132IPR015710
DomainOtopetrin

OTOP3 OTOP1

3.85e-0432132PF03189
DomainGPCR_2_latrophilin_rcpt_C

ADGRL3 ADGRL1

3.85e-0432132IPR003334
DomainDP

TFDP3 TFDP1

3.85e-0432132SM01138
DomainOtopetrin

OTOP3 OTOP1

3.85e-0432132IPR004878
Domain-

FBXW10B WDR43 WDR75 FBXW11 SEMA4B NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

4.60e-04333213122.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW10B WDR43 WDR75 FBXW11 SEMA4B NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

4.86e-0433521312IPR015943
DomainClathrin/coatomer_adapt-like_N

NCAPD2 AP1G2 AP3D1

6.01e-04152133IPR002553
DomainPI3/4_kinase_CS

PIK3C2G PRKDC ATM

6.01e-04152133IPR018936
DomainAdaptin_N

NCAPD2 AP1G2 AP3D1

6.01e-04152133PF01602
DomainWD40_repeat_dom

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

6.31e-0429721311IPR017986
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPB

7.65e-0442132IPR014930
DomainBile_Hydr_Trans

ACOT4 ACOT1

7.65e-0442132PF04775
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPB

7.65e-0442132PD011252
DomainThio_Ohase/aa_AcTrfase

ACOT4 ACOT1

7.65e-0442132IPR006862
DomainAcyl-CoA_thioEstase_long-chain

ACOT4 ACOT1

7.65e-0442132IPR016662
DomainDMPK_coil

CDC42BPG CDC42BPB

7.65e-0442132PF08826
DomainMFS_dom

SLCO1B3 SLC2A9 SLCO5A1 SLCO4C1 SLC15A2 SV2C MFSD5

8.79e-041342137IPR020846
DomainHEAT_REPEAT

DNAAF5 MROH7 AP3D1 HEATR4 PRKDC

1.22e-03702135PS50077
DomainGal_Lectin

ADGRL3 ADGRL1

1.27e-0352132PF02140
DomainGPCR_2_latrophilin

ADGRL3 ADGRL1

1.27e-0352132IPR003924
DomainLectin_gal-bd_dom

ADGRL3 ADGRL1

1.27e-0352132IPR000922
DomainFATC

PRKDC ATM

1.27e-0352132PF02260
DomainSUEL_LECTIN

ADGRL3 ADGRL1

1.27e-0352132PS50228
DomainSAM_2

PPFIA4 PPFIA2 PPFIA1 EPHA4

1.43e-03432134PF07647
Domain-

F8 HECTD1 CPXM2 EPHA4 EPHB1

1.47e-037321352.60.120.260
DomainMFS

SLCO1B3 SLC2A9 SLCO5A1 SLCO4C1 SV2C MFSD5

1.49e-031082136PS50850
DomainOlfact_rcpt

OR5T1 OR6K2 OR13D1 OR8B12 OR5B17 OR8K3 OR3A2 OR2A12 OR4A16 OR52H1 OR10W1 OR51G1

1.92e-0339321312IPR000725
DomainABC_tran

ABCC4 ABCA13 ABCG1 ABCA6

2.16e-03482134PF00005
DomainHEAT

DNAAF5 NCAPD2 HEATR4 PRKDC

2.16e-03482134PF02985
DomainABC_TRANSPORTER_2

ABCC4 ABCA13 ABCG1 ABCA6

2.16e-03482134PS50893
DomainABC_TRANSPORTER_1

ABCC4 ABCA13 ABCG1 ABCA6

2.33e-03492134PS00211
DomainABC_transporter-like

ABCC4 ABCA13 ABCG1 ABCA6

2.51e-03502134IPR003439
DomainCAMSAP_CH

VAV3 VAV1

2.62e-0372132PF11971
DomainCAMSAP_CH

VAV3 VAV1

2.62e-0372132IPR022613
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ABCC4 CCND1 TRRAP DNAAF5 PKD2 PLA2G6 HECTD1 FBXW11 CDC42BPG DIP2B FLNB ITCH PPFIA2 CAPN1 FRMPD1 AAK1 ADGRL1 ZSWIM6 TBL1XR1 CDC42BPB PPP2R2C ABCG1 THADA CMIP KYAT3 RASEF SPIDR PCCA KDM4B RAI1

2.82e-0814892223028611215
Pubmed

Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese population.

GCKR SLC2A9 NR5A1

2.57e-073222325283508
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EXOSC8 TRRAP CCDC3 NCAPD2 AP1G2 TLN2 PLA2G6 HECTD1 AP3D1 DYNC1H1 SEMA4B ADGRL1 FAAP100 CDC42BPB CNPPD1 TLNRD1 THADA KANK3 LRP4 PRKDC WDFY3 MFSD5 RAI1

7.64e-0711052222335748872
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WAPL ZNF302 ZNF624 TLN2 TAF1 HECTD1 PLP1 COG4 DYNC1H1 FBXW11 KLHL4 FLNB PMS2 ITCH ACOT1 CBR1 CDC42BPB TDP2 CNPPD1 UBE2O MRPS9 LRP4 PRKDC ATM WDFY3

8.42e-0712852222535914814
Pubmed

The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.

PPFIA4 PPFIA2 PPFIA1

2.54e-065222319013515
Pubmed

Vav family GEFs link activated Ephs to endocytosis and axon guidance.

VAV3 VAV1 EPHA4

2.54e-065222315848800
Pubmed

Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

ACOT4 ACOT1 ACOT6

2.54e-065222316940157
Pubmed

Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.

PPFIA4 PPFIA2 PPFIA1

5.06e-066222321618221
Pubmed

Genome-wide association study of multiplex schizophrenia pedigrees.

PPFIA2 TMTC1 EXOC2

5.06e-066222322885689
Pubmed

Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.

PPFIA4 PPFIA2 PPFIA1

8.81e-067222311931740
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

WAPL EXOSC8 TRRAP WDR43 FSIP2 CTHRC1 TAF1 BAZ2B TBL1XR1 KIF20B TFDP1 UBE2O FRG1 KDM4B RAI1

9.79e-066082221536089195
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

STRIP2 PPFIA2 PPFIA1 PPP2R2C PPP2R5B

1.12e-0546222518782753
Pubmed

Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis.

IL16 FAH TLNRD1

1.40e-058222311247670
Pubmed

Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.

OTOP3 SLC2A9 OTOP1

1.40e-058222312651873
Pubmed

Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons.

ISL2 EPHA4 EPHB1

2.10e-059222310704386
Pubmed

Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.

PPFIA4 PPFIA2 PPFIA1

2.10e-059222312629171
Pubmed

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

ACOT4 ACOT1 ACOT6

2.10e-059222316103133
Pubmed

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

PPFIA4 PPFIA2 PPFIA1

2.10e-059222312923177
Pubmed

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

TFDP3 CCND1 TFDP1

2.98e-051022237797074
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

TRRAP PRKDC ATM

2.98e-0510222318160036
Pubmed

Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.

PRKDC ATM

4.06e-052222211231155
Pubmed

Latrophilin receptors: novel bronchodilator targets in asthma.

ADGRL3 ADGRL1

4.06e-052222227325752
Pubmed

B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.

VAV3 VAV1

4.06e-052222219586920
Pubmed

Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.

PRKDC ATM

4.06e-052222210464290
Pubmed

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

PRKDC ATM

4.06e-052222227939942
Pubmed

The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.

PRKDC ATM

4.06e-052222221487018
Pubmed

Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.

PRKDC ATM

4.06e-052222226057167
Pubmed

Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.

SLCO1B3 SLC15A2

4.06e-052222229234073
Pubmed

Expression pattern of ATM and cyclin D1 in ductal carcinoma, normal adjacent and normal breast tissues of Iranian breast cancer patients.

CCND1 ATM

4.06e-052222221850541
Pubmed

The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X chromosomes.

PLP1 POU3F4

4.06e-05222227911044
Pubmed

A DP1 pseudogene derived from an aberrantly processed RNA.

TFDP3 TFDP1

4.06e-05222229161421
Pubmed

ATM kinase activity modulates ITCH E3-ubiquitin ligase activity.

ITCH ATM

4.06e-052222223435430
Pubmed

Genetic analysis of the cytoplasmic dynein subunit families.

DYNC1H1 DYNC2H1

4.06e-052222216440056
Pubmed

Modulation of E2F activity is linked to interferon-induced growth suppression of hematopoietic cells.

TFDP3 TFDP1

4.06e-05222229139687
Pubmed

ATM is required for rapid degradation of cyclin D1 in response to gamma-irradiation.

CCND1 ATM

4.06e-052222219071090
Pubmed

Quantitative analysis of Cyclin D1 and CD23 expression in mantle cell lymphoma and B-chronic lymphocytic leukemia.

CCND1 FCER2

4.06e-052222212127555
Pubmed

DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.

PRKDC ATM

4.06e-052222219071136
Pubmed

STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.

STAT4 PRKDC

4.06e-052222218802110
Pubmed

Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.

PRKDC ATM

4.06e-052222212065055
Pubmed

Lyn tyrosine kinase promotes silencing of ATM-dependent checkpoint signaling during recovery from DNA double-strand breaks.

ATM LYN

4.06e-052222225173936
Pubmed

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

PRKDC ATM

4.06e-052222217189255
Pubmed

A new component of the transcription factor DRTF1/E2F.

TFDP3 TFDP1

4.06e-05222228413592
Pubmed

AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.

PRKDC ATM

4.06e-052222222972376
Pubmed

G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.

PRKDC ATM

4.06e-052222226774662
Pubmed

Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis.

TFDP3 TFDP1

4.06e-052222211429786
Pubmed

Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.

SLCO1B3 SLCO4C1

4.06e-052222214993604
Pubmed

Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.

PRKDC LYN

4.06e-05222229748231
Pubmed

DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.

PRKDC ATM

4.06e-052222236727301
Pubmed

A new component of the transcription factor DRTF1/E2F.

TFDP3 TFDP1

4.06e-05222228446173
Pubmed

The diagnosis values of serum STAT4 and sEng in preeclampsia.

STAT4 ENG

4.06e-052222231628681
Pubmed

The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.

FRMPD1 GPSM1

4.06e-052222218566450
Pubmed

Loss of protein phosphatase 2A expression correlates with phosphorylation of DP-1 and reversal of dysplasia through differentiation in a conditional mouse model of cancer progression.

TFDP3 TFDP1

4.06e-052222214633688
Pubmed

Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.

PRKDC ATM

4.06e-052222232674014
Pubmed

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.

CYP4F8 CYP4F12

4.06e-052222216112640
Pubmed

Prognostic significance of ATM and cyclin B1 in pancreatic neuroendocrine tumor.

CCND1 ATM

4.06e-052222222707287
Pubmed

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

VAV1 SOCS1

4.06e-052222210747851
Pubmed

A relative signalling model for the formation of a topographic neural map.

ISL2 EPHA4

4.06e-052222215483613
Pubmed

Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.

DYNC1H1 DYNC2H1

4.06e-052222225502651
Pubmed

Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.

PRKDC ATM

4.06e-052222221245310
Pubmed

Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.

ADSS2 ATM

4.06e-052222219115993
Pubmed

The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.

PRKDC ATM

4.06e-052222217593081
Pubmed

Identification of rare genetic variants in novel loci associated with Paget's disease of bone.

DCSTAMP CTHRC1

4.06e-052222224370779
Pubmed

PPFIA1 and CCND1 are frequently coamplified in breast cancer.

CCND1 PPFIA1

4.06e-052222219787783
Pubmed

Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription.

CCND1 TAF1

4.06e-05222229926939
Pubmed

Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.

PRKDC ATM

4.06e-052222220617180
Pubmed

ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis.

CCND1 ATM

4.06e-052222223318439
Pubmed

DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.

PRKDC ATM

4.06e-052222218172300
Pubmed

The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer.

STAT4 SOCS1

4.06e-052222238774752
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

TRRAP PRKDC ATM

4.08e-0511222320427287
Pubmed

SRC family kinases are required for limb trajectory selection by spinal motor axons.

LYN EPHA4 EPHB1

4.08e-0511222319403835
Pubmed

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1.

CCND1 CACNG5 NR5A1 PLCE1

4.44e-0531222416702404
Pubmed

The synaptic vesicle cycle.

PPFIA4 PPFIA2 PPFIA1 SV2C

4.44e-0531222415217342
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

NCAPD2 MROH7 HECTD1 AP3D1 FLNB MYO1B CDC42BPB PRKDC

5.03e-05202222833005030
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PPFIA4 PPFIA2 PPFIA1

5.41e-051222239624153
Pubmed

A cohesin-RAD21 interactome.

WAPL NCAPD2 DIP2B FLNB CAPN1 CBR1 UBE2O PRKDC

6.18e-05208222822145905
Pubmed

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

FCER2 PRKDC LYN

7.00e-0513222322724066
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5T1 OR6K2 OR13D1 OR8B12 OR8K3 OR2A12 OR4A16 OR52H1 OR10W1 OR51G1

7.33e-053402221011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5T1 OR6K2 OR13D1 OR8B12 OR8K3 OR2A12 OR4A16 OR52H1 OR10W1 OR51G1

7.33e-053402221011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5T1 OR6K2 OR13D1 OR8B12 OR8K3 OR2A12 OR4A16 OR52H1 OR10W1 OR51G1

7.88e-053432221032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5T1 OR6K2 OR13D1 OR8B12 OR8K3 OR2A12 OR4A16 OR52H1 OR10W1 OR51G1

8.47e-053462221014611657
Pubmed

Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord.

ISL2 EPHA4 EPHB1

1.10e-0415222328595615
Pubmed

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

DYNC1H1 ELP2 PRKDC

1.10e-0415222318303054
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL3 ADGRL1

1.21e-043222210994649
Pubmed

Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.

VAV3 VAV1

1.21e-043222217054426
Pubmed

Genetic dissection of EphA receptor signaling dynamics during retinotopic mapping.

ISL2 EPHA4

1.21e-043222221753007
Pubmed

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.

PRKDC ATM

1.21e-04322229766667
Pubmed

Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions.

VAV3 VAV1

1.21e-043222226240279
Pubmed

Identification and characterization of FUS/TLS as a new target of ATM.

PRKDC ATM

1.21e-043222218620545
Pubmed

Severe hypoxia increases expression of ATM and DNA-PKcs and it increases their activities through Src and AMPK signaling pathways.

PRKDC ATM

1.21e-043222230224064
Pubmed

Variation in telangiectasia predisposing genes is associated with overall radiation toxicity.

ATM ENG

1.21e-043222222677372
Pubmed

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

PRKDC ATM

1.21e-043222218644470
Pubmed

SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin.

VAV3 VAV1

1.21e-04322228622875
Pubmed

Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.

PRKDC ATM

1.21e-043222218451257
Pubmed

Expression of the E2F-1/DP-1 transcription factor in murine development.

TFDP3 TFDP1

1.21e-04322228788032
Pubmed

Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.

TFDP3 TFDP1

1.21e-04322228405995
Pubmed

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

PRKDC ATM

1.21e-043222223836881
Pubmed

DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.

PRKDC ATM

1.21e-043222227733644
Pubmed

Cytoplasmic dynein promotes HIV-1 uncoating.

DYNC1H1 DYNC2H1

1.21e-043222225375884
Pubmed

NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and β-catenin accumulation.

NR5A1 PRKDC

1.21e-043222225421435
Pubmed

p53, Cyclin-D1, β-catenin, APC and c-myc in Tumor Tissue from Colorectal and Gastric Cancer Patients with Suspected Lynch Syndrome by the Bethesda Criteria.

CCND1 PMS2

1.21e-043222232102509
Cytoband14q24.3

ACOT4 BBOF1 HEATR4 ACOT1 ACOT6

9.49e-0593223514q24.3
GeneFamilyWD repeat domain containing

FBXW10B WDR43 WDR75 FBXW11 NWD1 TBL1XR1 WDFY4 PPP2R2C GNB4 ELP2 WDFY3

9.99e-0626214711362
GeneFamilyAcyl-CoA thioesterases

ACOT4 ACOT1 ACOT6

6.06e-0510147341
GeneFamilyTranscription factor Dp family

TFDP3 TFDP1

1.96e-0431472987
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL3 ADGRL1

3.90e-0441472918
GeneFamilySterile alpha motif domain containing

PPFIA4 PPFIA2 PPFIA1 EPHA4 EPHB1

7.56e-04881475760
GeneFamilySH2 domain containing

STAT4 VAV3 VAV1 SOCS1 LYN

1.41e-031011475741
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 WDFY3

2.28e-03914721230
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW11

3.44e-03111472559
CoexpressionSCHEIDEREIT_IKK_INTERACTING_PROTEINS

PDK1 CCND1 VAV1 NLRP2 CARD11 ATM

4.73e-06532156M6303
CoexpressionAtlasspleen

GDPD2 GPR55 FCER2 KCNT1 DNASE1L3 OTOA WDFY4 TMTC1 KANK3 CARD11 NR5A1 LYN IGSF21

1.20e-0531520413spleen
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G SCN7A HECTD1 FLNB CPXM2 DYNC2H1 MYO1B TOP6BL PPP2R2C ABCA6 PCCA

2.93e-0918722311f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G SCN7A HECTD1 FLNB CPXM2 DYNC2H1 MYO1B TOP6BL PPP2R2C ABCA6 PCCA

3.28e-0918922311e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 PIK3C2G TLN2 UNC79 ADGRL3 OTOA PPFIA2 PIEZO2 MYH15 PLCE1

3.30e-08184223102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 PIK3C2G TLN2 UNC79 ADGRL3 OTOA PPFIA2 PIEZO2 MYH15 PLCE1

3.30e-08184223102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 PIK3C2G TLN2 UNC79 ADGRL3 OTOA PPFIA2 PIEZO2 MYH15 PLCE1

3.30e-0818422310ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

DOCK4 F8 BMP6 VAV3 DNASE1L3 FLNB TMTC1 CMIP ENG EPHA4

5.17e-08193223102531266bc57339d4e2b22a88817008e32b8c1598
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

DOCK4 F8 BMP6 VAV3 DNASE1L3 FLNB TMTC1 CMIP ENG EPHA4

5.17e-081932231001c2df9206f1527c578e808978e58196c35e72f5
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 DNASE1L3 VAV1 SEMA4B WDFY4 ABHD17B CARD11 LYN IGSF21

2.72e-071762239077f3fe5e3482ea3f639d789bd3d584161b36c02
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 DNASE1L3 VAV1 SEMA4B WDFY4 ABHD17B CARD11 LYN IGSF21

2.72e-071762239fc2ba468677b19b55130c1f06737f40300cd9d2e
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 DCSTAMP STRIP2 OTULINL DNASE1L3 PPFIA4 WDFY4 TBC1D8 CARD11

3.00e-0717822398c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCND1 SCN7A VAV3 KLHL4 ICAM2 ABCG1 PIEZO2 LYN ENG

3.14e-071792239d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CCDC3 PKD2 ADGRL3 FLNB CPXM2 PPFIA2 SLIT3 MYH15 ENPEP

3.78e-071832239818fd886e0188091310825f9145fa53328f2c979
ToppCellP07-Endothelial-capillary_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A TCN2 ICAM2 TLNRD1 PIEZO2 KANK3 LYN ENG

4.34e-07186223972aab20b848dd9e1101a4bc2466e08aed5f8bbb6
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

ABCC4 F8 BMP6 FLNB ICAM2 TMTC1 CMIP ENG EPHA4

4.54e-07187223940ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

F8 CTHRC1 VAV3 FBXO39 KLHL4 CPXM2 TMTC1 KANK3 EPHB1

4.96e-0718922390d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellP03-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A VAV3 TCN2 ICAM2 PIEZO2 KANK3 LYN ENG

5.19e-071902239347c7bf67ade235a4e2320db6a75ce0dab8744f9
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

CCND1 F8 DNASE1L3 FLNB TCN2 ICAM2 ATP9A KANK3 ENG

5.19e-0719022396b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCellP03-Endothelial-unknown_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A VAV3 TCN2 ICAM2 PIEZO2 KANK3 LYN ENG

5.19e-0719022390c7da05fbd3f095dde7550585209c056f0b76990
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

DOCK4 F8 BMP6 DNASE1L3 FLNB ICAM2 TMTC1 CMIP ENG

5.42e-071912239c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 F8 CCDC3 DNASE1L3 TBC1D8 TMTC1 ABCG1 KANK3 EPHA4

5.66e-07192223927ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C2CD4B SLCO1B3 BMP6 ADGRL3 FLNB ICAM2 TLNRD1 ENG EPHB1

5.66e-0719222390aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 C2CD4B BMP6 DNASE1L3 FLNB TMTC1 ABCG1 KANK3 ENG

6.45e-071952239818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B F8 DNASE1L3 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.02e-071972239951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B F8 DNASE1L3 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.02e-0719722397caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

C2CD4B CCDC3 DNASE1L3 CPXM2 TMTC1 ABCG1 KANK3 ENG EPHA4

7.32e-0719822395c82dad416938d5c460069796d808170e7dbc8d9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 BMP6 DNASE1L3 TMTC1 ABCG1 KANK3 ENG EPHA4

7.32e-071982239440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 BMP6 DNASE1L3 TMTC1 ABCG1 KANK3 ENG EPHA4

7.32e-071982239451003a21162eeae90739fdb502bb50b362d80c8
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 F8 CCDC3 ICAM2 TMTC1 ABCG1 KANK3 ENG EPHA4

7.32e-0719822398689090bce9ab6e8f122426a404037e572c6713b
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C2CD4B F8 CTHRC1 DNASE1L3 CPXM2 ICAM2 TMTC1 KANK3 ENG

7.96e-072002239310c75e13be9194312a8b686804edcf13d44caf5
ToppCellCD8+_Memory_T_cell-RSV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IL16 PDK1 CCND1 TLN2 OTULINL PPFIA4 MKNK2 TOGARAM2

1.57e-061612238f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCND1 STRIP2 PLA2G4F PPFIA4 WDFY4 SLCO5A1 CARD11 PLCE1

2.26e-061692238b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDK1 FCER2 VAV1 WDFY4 MYH15 CARD11 ATM LYN

2.36e-061702238a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCND1 STRIP2 FAH DNASE1L3 TBC1D8 SLCO5A1 ULBP1 GNB4

2.81e-0617422387be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR55 DCSTAMP STRIP2 DNASE1L3 VAV1 PPFIA4 WDFY4 CARD11

2.81e-0617422386688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF527 C2CD4B PDK1 SCN7A DNASE1L3 CDC42BPG CDH19 PIEZO2

2.93e-0617522389a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF527 C2CD4B PDK1 SCN7A DNASE1L3 CDC42BPG CDH19 PIEZO2

2.93e-0617522382b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCND1 STRIP2 FAH DNASE1L3 TBC1D8 SLCO5A1 ULBP1 GNB4

2.93e-0617522381b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF527 C2CD4B PDK1 SCN7A DNASE1L3 CDC42BPG CDH19 PIEZO2

2.93e-06175223854c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

CCND1 FSIP2 DNASE1L3 FLNB WDFY4 SLCO5A1 ABCA6 IGSF21

3.76e-0618122385a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 STRIP2 OTULINL DNASE1L3 VAV1 PPFIA4 WDFY4 TBC1D8

3.92e-061822238df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC79 PLP1 ADGRL3 ACOT1 CDH19 OTOP1 CACNG5 IGSF21

3.92e-06182223882ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 STRIP2 OTULINL DNASE1L3 VAV1 PPFIA4 WDFY4 TBC1D8

4.08e-061832238062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

RAD21L1 CCND1 DNASE1L3 WDFY4 SLCO5A1 CARD11 IGSF21 ATP6V0A2

4.25e-061842238c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellwk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

F8 PIK3C2G CCDC3 CTHRC1 KLHL4 TMTC1 KANK3 SV2C

4.79e-06187223855aad84b992412e487a32f4970620189a7380ba6
ToppCellP03-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A VAV3 TCN2 ICAM2 ABCG1 PIEZO2 LYN

4.79e-06187223855618ceec367c1c51ed5c447063d7fbd5c7e0808
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD2 PLP1 ADGRL3 POU3F4 ACOT1 PPP2R2C OTOP1 CACNG5

4.98e-061882238c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD2 PLP1 ADGRL3 POU3F4 ACOT1 PPP2R2C OTOP1 CACNG5

4.98e-0618822383b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCellP07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A TCN2 ICAM2 TLNRD1 KANK3 LYN ENG

4.98e-061882238ee8ff134a639deca2bb3027c4d3291f48c12d171
ToppCellP15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A TLN2 VAV3 ICAM2 ABCG1 PIEZO2 LYN

4.98e-061882238c0a03e33027f52b5c25ffbc8f822128e5160ed20
ToppCellP07-Endothelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND1 SCN7A TCN2 ICAM2 TLNRD1 KANK3 LYN ENG

5.18e-061892238d62b5b5c3cd259befa7afb19f45e3804e2ab80f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 BMP6 CCDC3 ICAM2 TMTC1 ENG EPHA4

5.38e-061902238bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

F8 CTHRC1 KLHL4 CPXM2 TMTC1 KANK3 SV2C EPHB1

5.38e-061902238103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 F8 BMP6 CCDC3 TMTC1 GNB4 ENG EPHA4

5.38e-0619022381519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK4 ABCC4 BMP6 CPXM2 TCN2 TMTC1 CMIP KANK3

5.38e-06190223878e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCND1 SCN7A KLHL4 ICAM2 ABCG1 PIEZO2 KANK3 ENG

5.59e-06191223844c596984c6196f6014e0e405dbe5560841e54ff
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCND1 SCN7A KLHL4 ICAM2 ABCG1 PIEZO2 KANK3 ENG

5.59e-061912238e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C2CD4B SLCO1B3 ADGRL3 TLNRD1 SYT16 TMTC1 ENG EPHB1

5.81e-06192223852acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

VAV3 VAV1 SLC2A9 ZSWIM6 WDFY4 CMIP LYN IGSF21

5.81e-0619222387be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

DOCK4 F8 BMP6 DNASE1L3 FLNB ICAM2 TMTC1 ENG

5.81e-0619222388a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCND1 SCN7A TLN2 ICAM2 KIAA1549 TMTC1 PIEZO2 ENG

5.81e-06192223835f7926628a967f85b26371e795a1b93c6f103ab
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

VAV3 VAV1 SLC2A9 WDFY4 CMIP SPIDR LYN IGSF21

5.81e-061922238a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

VAV3 VAV1 SLC2A9 ZSWIM6 WDFY4 CMIP LYN IGSF21

6.04e-06193223812bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 SLCO1B3 BMP6 VAV3 ADGRL3 KLHL4 BAZ2B PIEZO2

6.04e-061932238e1d546165dcc2392f540162206852c4717d7306f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 BMP6 CCDC3 ICAM2 TMTC1 KANK3 ENG EPHA4

6.04e-0619322386a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL16 TLN2 OTULINL VAV1 OTOA AAK1 GNB4 LYN

6.04e-061932238b52d5661edff83ac4c5fe2bf89d6672016bb827b
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 IL16 SCN7A TLN2 PIEZO2 ABCA6 SLIT3 GPSM1

6.27e-061942238e93de9428c986b8943fc169258847c650cfab0e5
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

VAV3 VAV1 SLC2A9 ZSWIM6 WDFY4 CMIP LYN IGSF21

6.27e-061942238c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 F8 DNASE1L3 TBC1D8 TMTC1 PIEZO2 KANK3 ENG

6.27e-061942238660535b492445063d965095a50e1e299ce04c50a
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

C2CD4B BMP6 FBXO39 KLHL4 ADGRL1 PIEZO2 KANK3 ENG

6.51e-06195223822a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

VAV3 VAV1 SLC2A9 ZSWIM6 WDFY4 CMIP LYN IGSF21

6.51e-0619522385e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN7A TLN2 ICAM2 KIAA1549 TMTC1 ABCG1 PIEZO2 LRP4

6.51e-0619522387e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 UPK1B SEMA4B MYO1B SLC15A2 LYN EPHA4 PLCE1

6.76e-061962238b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 ICAM2 TLNRD1 TMTC1 PIEZO2 KANK3 ENG

6.76e-06196223865d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F8 BMP6 DNASE1L3 TCN2 ICAM2 TLNRD1 KANK3 ENG

6.76e-06196223881900dcc9451ff6606ec940c16b559d73247590e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 UPK1B SEMA4B MYO1B SLC15A2 LYN EPHA4 PLCE1

6.76e-061962238c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 CCND1 F8 ICAM2 TMTC1 PIEZO2 KANK3 ENG

6.76e-061962238d323f7dc41380446e5967c69832bea88351a9331
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR55 FCER2 VAV3 VAV1 UTS2B WDFY4 CARD11 LYN

7.01e-061972238ccabb976b5d4800e87e550640454a893fdb3b1b6
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC3 ICAM2 TMTC1 ABCG1 KANK3 GNB4 ENG EPHA4

7.28e-061982238f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 TBC1D8 TMTC1 PIEZO2 KANK3 ENG EPHA4

7.28e-06198223892416e65a0dc1a4bf931833407620ea05d362f56
ToppCellEndoth-Vasc|World / shred by cell class for parenchyma

C2CD4B F8 DNASE1L3 ICAM2 TMTC1 ABCG1 KANK3 ENG

7.28e-061982238067101d070cfaf84c7d16c6e517f8946690ad502
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

C2CD4B F8 DNASE1L3 CPXM2 TCN2 TMTC1 KANK3 ENG

7.28e-06198223844f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCellcellseq2-Endothelial|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C2CD4B F8 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.83e-06200223881bdf7a1ddc3e82b96526449e662cca26d7297b1
ToppCellcellseq2-Endothelial-Endothelial_Vascular|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C2CD4B F8 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.83e-062002238dc244a5ccec1b793dc4371fb2cd2c3fd4226283e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 DNASE1L3 ICAM2 TLNRD1 TMTC1 KANK3 ENG

7.83e-062002238ced14d83222dbebca85c40540e76824e683354f3
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C2CD4B F8 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.83e-062002238147ceed692655f4ed73b8a57b0b3224def1f3055
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C2CD4B F8 CPXM2 ICAM2 TMTC1 KANK3 ENG EPHA4

7.83e-0620022380afc7a0f87eac48f772759c3b626758089733361
ToppCellTransverse-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

CCND1 DNASE1L3 FLNB WDFY4 ULBP1 SPIDR ATP6V0A2

1.13e-0515122376870f3b5d2bfad849c3203658b5f28f0ae181295
ToppCell18-Distal-Epithelial-Basal_cell|Distal / Age, Tissue, Lineage and Cell class

NIF3L1 ACOT4 F8 PKP1 NLRP2 TBC1D8 SLC15A2

1.51e-051582237183f445967e09e871c93d8e94781ed9fec894169
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B BMP6 VAV3 FBXO39 OTOA ABCG1 EPHB1

1.58e-0515922370a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B BMP6 VAV3 FBXO39 OTOA ABCG1 EPHB1

1.58e-051592237299e2162a82e31196d7f3a110c2db622349edfff
ToppCellBAL-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

CCND1 DNASE1L3 FLNB KIAA1549 TOP6BL WDFY4 SLIT3

1.92e-0516422374bd9629d054545d1e3f9e5c127b5ac2388637106
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B BMP6 SCN7A FBXO39 PIEZO2 SLIT3 EPHB1

2.08e-0516622377286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

C2CD4B BMP6 SCN7A FBXO39 PIEZO2 SLIT3 EPHB1

2.08e-0516622377c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCelldroplet-Lung-LUNG-1m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCND1 STRIP2 FAH DNASE1L3 SLCO5A1 ULBP1 GNB4

2.16e-051672237e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 GDPD2 PIK3C2G PKP1 PLA2G4F TOGARAM2 LRP4

2.16e-05167223702c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD2 DNASE1L3 MMS22L WDFY4 ULBP1 CARD11 CLSPN

2.25e-0516822379b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD2 DNASE1L3 MMS22L WDFY4 ULBP1 CARD11 CLSPN

2.25e-0516822374b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD2 DNASE1L3 MMS22L WDFY4 ULBP1 CARD11 CLSPN

2.25e-051682237c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 F8 TBC1D8 TMTC1 PIEZO2 ENG EPHA4

2.33e-051692237987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DNASE1L3 BAZ2B FRMPD1 ABCA6 ZNF667 CARD11 EPHB1

2.33e-051692237632aa3ab39ec87bafcefec6cddf71129a054d3b0
DiseaseAdenocarcinoma of large intestine

TRRAP TAF1 PMS2 TBL1XR1 CDC42BPB PRKDC ATM

5.48e-06962087C1319315
DiseaseColorectal Carcinoma

ABCC4 ABCA13 SLCO1B3 CCND1 BMP6 ZNF624 DNASE1L3 PMS2 TCN2 ZNF569 MYO1B ADAM29 CNPPD1 ABCG1 ABCA6 GNB4 IGSF21

1.12e-0570220817C0009402
DiseaseX-17653 measurement

ACOT4 HEATR4 ACOT6

2.81e-0592083EFO_0800783
Diseasemelanoma

CCND1 TRRAP GOPC CAPN1 MYO1B SLC15A2 ATM KDM4B RAI1

7.16e-052482089C0025202
Diseaseundecenoylcarnitine (C11:1) measurement

ACOT4 HEATR4 ACOT6

9.37e-05132083EFO_0800588
Diseasedehydroepiandrosterone sulphate measurement

DOCK4 ABCA13 TMTC1 THADA CMIP

1.21e-04682085EFO_0007001
Diseasecardiovascular event measurement, response to placebo

ACOT4 ACOT6

1.48e-0432082EFO_0006919, EFO_0008344
DiseaseMalignant lymphoma - lymphocytic, intermediate differentiation

CCND1 ATM

1.48e-0432082C0555202
DiseaseColorectal Neoplasms

ABCC4 ABCA13 SLCO1B3 TCN2 ZNF569 CNPPD1 ABCG1 ABCA6 GNB4

1.65e-042772089C0009404
DiseaseCarcinoma of bladder

TBL1XR1 ATM EPHA4

2.61e-04182083C0699885
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 WDFY3

2.94e-0442082DOID:2935 (implicated_via_orthology)
Diseasetranscobalamin-2 measurement

TCN2 KANK3

2.94e-0442082EFO_0802139
Diseaselimited scleroderma

STAT4 DNASE1L3 EXOC2

3.08e-04192083EFO_1001017
DiseaseMedulloblastoma

VAV1 PMS2 ATM KDM4B

4.29e-04502084C0025149
Diseasecholesterol to total lipids in small VLDL percentage

ANKRD31 GCKR CMIP ABCA6

4.63e-04512084EFO_0022242
Diseasephosphatidylcholine 34:3 measurement

GCKR MYO1B PPP2R2C

4.82e-04222083EFO_0010377
Diseasetriglycerides to total lipids in very large VLDL percentage

ANKRD31 GCKR CMIP ABCA6

5.36e-04532084EFO_0022340
Diseaseairway responsiveness measurement

ABCC4 WDFY4 MYH15

6.26e-04242083EFO_0006897
Diseasemetabolite measurement

ABCC4 GCKR ACOT4 FBXO39 OTULINL SLC2A9 HEATR4 ACOT6 WDFY4 KYAT3 ENPEP EPHB1

6.69e-0456020812EFO_0004725
Diseasefree cholesterol to total lipids in medium VLDL percentage

ANKRD31 GCKR CMIP ABCA6

7.07e-04572084EFO_0022284
Diseaserenal system measurement, uric acid measurement

PKD2 SLC2A9

7.28e-0462082EFO_0004742, EFO_0004761
Diseasetriglycerides to total lipids in small VLDL percentage

ANKRD31 GCKR CMIP ABCA6

7.56e-04582084EFO_0022338
Diseaseazoospermia (implicated_via_orthology)

CDC42BPG GOPC CDC42BPB

8.91e-04272083DOID:14227 (implicated_via_orthology)
DiseaseX-16935 measurement

ACOT4 ACOT6

1.01e-0372082EFO_0800763
Diseasetriglycerides to total lipids in medium VLDL percentage

ANKRD31 GCKR CMIP ABCA6

1.03e-03632084EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

ANKRD31 GCKR CMIP ABCA6

1.03e-03632084EFO_0022239
DiseaseAdult T-Cell Lymphoma/Leukemia

BMP6 VAV1 CARD11

1.34e-03312083C0023493
DiseaseX-24747 measurement

ACOT4 ACOT6

1.35e-0382082EFO_0022135
DiseasePure Gonadal Dysgenesis, 46, XX

NR5A1 SPIDR

1.35e-0382082C0685837
Diseaseresponse to darapladib, cardiovascular event measurement

ACOT4 ACOT6

1.35e-0382082EFO_0006919, EFO_0008395
DiseaseGonadal Dysgenesis, 46,XX

NR5A1 SPIDR

1.35e-0382082C0949595
Diseasediastolic blood pressure, self reported educational attainment

PIK3C2G SLIT3

1.35e-0382082EFO_0004784, EFO_0006336
Diseasesevere acute respiratory syndrome, COVID-19

HAO1 FBXO47 ADSS2 PIK3C2G ADGRL3 KLHL4 SEMA4B PMS2 WDFY4 ELP2

1.35e-0344720810EFO_0000694, MONDO_0100096
Diseaseferritin measurement

GCKR OTOP3 WDR43 BAZ2B TOGARAM2

1.58e-031192085EFO_0004459
DiseaseEpstein Barr viral capsid antigen seropositivity

THADA CACNG5

1.72e-0392082EFO_0009272
Diseaseacute lymphoblastic leukemia (is_marker_for)

CCND1 TCN2 ENG

1.76e-03342083DOID:9952 (is_marker_for)
Diseasefree cholesterol to total lipids in large LDL percentage

GCKR CMIP ABCA6 KANK3

1.88e-03742084EFO_0022280
Diseasefree cholesterol to total lipids in small VLDL percentage

ANKRD31 GCKR CMIP ABCA6

1.97e-03752084EFO_0022287
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB CMIP

2.14e-03102082GO_0097327, GO_0097328
DiseaseSmall Lymphocytic Lymphoma

CCND1 ATM

2.14e-03102082C0855095
DiseaseB-CELL MALIGNANCY, LOW-GRADE

CCND1 ATM

2.14e-03102082C1868683
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

STAT4 DNASE1L3 FLNB

2.43e-03382083EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Diseasebirth weight, parental genotype effect measurement

CCND1 NLRP13 HKDC1 GPSM1 RAI1 PLCE1

2.48e-031922086EFO_0004344, EFO_0005939
Diseasesmall cell lung carcinoma

BMP6 A2ML1 DYNC2H1 EPHB1

2.50e-03802084EFO_0000702
Diseaseandrogenetic alopecia

CEP78 DIP2B KIF20B THADA PIEZO2

2.57e-031332085EFO_0004191
DiseaseX-11308 measurement

HEATR4 ACOT6

2.61e-03112082EFO_0800693
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG CDC42BPB

2.61e-03112082DOID:0060669 (implicated_via_orthology)
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 PLCE1

2.61e-03112082DOID:3717 (is_implicated_in)
Diseaseresponse to cisplatin, response to antineoplastic agent

HAO1 VAV3

2.61e-03112082GO_0072718, GO_0097327
Diseasegout

GCKR PKD2 HSP90AB3P CDC42BPG SLC2A9 ABCG1

2.75e-031962086EFO_0004274
Diseasemismatch repair cancer syndrome (is_implicated_in)

PMS2 TFDP1

3.12e-03122082DOID:0112182 (is_implicated_in)
Diseasealpha-hydroxybutyric acid measurement

ABCC4 GCKR

3.12e-03122082EFO_0010458
Diseaseintracranial aneurysm (is_implicated_in)

PKD2 ENG

3.12e-03122082DOID:10941 (is_implicated_in)
Diseasematrix metalloproteinase measurement

PLA2G6 DYNC2H1

3.66e-03132082EFO_0004744
DiseaseX-24588 measurement

SLCO1B3 HEATR4

3.66e-03132082EFO_0800898
DiseaseConnective Tissue Diseases

PKD2 PIEZO2

3.66e-03132082C0009782
Diseaselymphocyte count

IL16 GCKR PLA2G6 OBI1 AP3D1 VAV1 FLNB MMS22L NWD1 PPFIA1 HKDC1 THADA UBE2O CMIP KYAT3 CARD11 ATM KDM4B RAI1 PLCE1

3.70e-03146420820EFO_0004587
Diseaseamyloid-beta measurement

ABCC4 STAT4 WDR75 SHOC1 TOGARAM2 THADA CMIP PRKDC

3.86e-033552088EFO_0005194
DiseaseGastric Adenocarcinoma

TRRAP ATM EPHB1

3.94e-03452083C0278701
Diseasecholesterol to total lipids in large VLDL percentage

ANKRD31 GCKR ABCA6

3.94e-03452083EFO_0022236
Diseaseuric acid measurement

GCKR PKD2 CDC42BPG SLC2A9 DYNC2H1 AAK1 TOP6BL PPP2R5B ABCA6 SLC15A2 KDM4B

4.21e-0361020811EFO_0004761
Diseasediffuse large B-cell lymphoma

CDC42BPB EXOC2

4.26e-03142082EFO_0000403
DiseaseProstatic Neoplasms

ABCC4 IL16 CCND1 HAO1 VAV3 TCN2 TBL1XR1 CBR1 RLIM PRKDC ATM

4.53e-0361620811C0033578
DiseaseMalignant neoplasm of prostate

ABCC4 IL16 CCND1 HAO1 VAV3 TCN2 TBL1XR1 CBR1 RLIM PRKDC ATM

4.53e-0361620811C0376358
Diseaseurate measurement

GCKR PKD2 HSP90AB3P CDC42BPG SLC2A9 CAPN1 AAK1 TOP6BL TBC1D8 CMIP LRP4 NR5A1 KDM4B EPHA4

4.67e-0389520814EFO_0004531
Diseaseovarian carcinoma (is_implicated_in)

CCND1 SOCS1

4.89e-03152082DOID:4001 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

TBL1XR1 ATM

4.89e-03152082C0496930
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

GCKR TMTC1

4.89e-03152082EFO_0006833, EFO_0006896
DiseaseBenign neoplasm of bladder

TBL1XR1 ATM

4.89e-03152082C0154017
DiseaseCarcinoma in situ of bladder

TBL1XR1 ATM

4.89e-03152082C0154091
DiseaseYKL40 measurement

GCKR PPFIA4

4.89e-03152082EFO_0004869
DiseaseX-17654 measurement

HEATR4 ACOT6

4.89e-03152082EFO_0800784
Diseasecholestasis (biomarker_via_orthology)

ABCC4 SLCO1B3 ENG

5.01e-03492083DOID:13580 (biomarker_via_orthology)
Diseasecholesteryl esters to total lipids in small VLDL percentage

ANKRD31 GCKR ABCA6

5.01e-03492083EFO_0022256
Diseaseprostate cancer (is_marker_for)

SLCO1B3 BMP6 PMS2 ENG KDM4B

5.07e-031562085DOID:10283 (is_marker_for)
Diseasetriacylglycerol 50:5 measurement

GCKR MYO1B

5.56e-03162082EFO_0010412
Diseaseendometriosis (biomarker_via_orthology)

VAV1 LYN

5.56e-03162082DOID:289 (biomarker_via_orthology)
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

CCND1 ATM

5.56e-03162082C0334634
Diseasegout, hyperuricemia

PKD2 SLC2A9

5.56e-03162082EFO_0004274, EFO_0009104
Diseasevenous thromboembolism

F8 ITCH TOGARAM2 ADAM29 NLRP2 PIEZO2 LRP4 SV2C IGSF21

5.58e-034602089EFO_0004286
Diseasesitting height ratio

PKD2 EXOC2 EPHB1

5.61e-03512083EFO_0007118
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

GCKR CMIP LRP4 EPHB1

6.16e-031032084EFO_0008595, EFO_0020944
Diseasephospholipids in large LDL measurement

ANKRD31 GCKR ABCA6

6.24e-03532083EFO_0022174
Diseasecholesteryl esters to total lipids in very large VLDL percentage

GCKR CMIP ABCA6

6.24e-03532083EFO_0022258
Diseasecyclic adenosine monophosphate measurement

ABCC4 NT5C1B

6.27e-03172082EFO_0010473
Diseaserenal fibrosis (implicated_via_orthology)

GPR21 ENG

6.27e-03172082DOID:0050855 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

DIP2B KDM4B

6.27e-03172082DOID:0060307 (is_implicated_in)
Diseasecholesterol to total lipids in very large VLDL percentage

GCKR CMIP ABCA6

6.58e-03542083EFO_0022244
DiseaseMetastatic melanoma

TAF1 PRKDC EPHA4

6.58e-03542083C0278883
Diseaseecosanoids measurement

SLCO1B3 ACOT4 ACOT6

6.92e-03552083EFO_0020044

Protein segments in the cluster

PeptideGeneStartEntry
ALSSCALFNMVDGRK

NT5C1B

311

Q96P26
LLSRKLAQCGVMFDF

PPP2R5B

76

Q15173
ELCLSMASFLKGITA

ACOT1

236

Q86TX2
RSCAIVTFMNKTLGT

ADAM29

311

Q9UKF5
LMSLSLSFLICNKGR

FAM223B

21

A6NKX1
SSSKGSLRLCDMRAA

PPP2R2C

241

Q9Y2T4
CTFTKMRSNSALRVL

CTHRC1

126

Q96CG8
GLDSASCFQVVSLMK

ABCG1

246

P45844
FLVRTSNGMKCALKR

AAK1

61

Q2M2I8
FSSIMKCDTGLRNSF

ACTRT3

276

Q9BYD9
AKQLAGMITFTCNLA

COG4

91

Q9H9E3
DKRSASNAFMVCGVL

ADGRL1

311

O94910
SDCLMVVQFLRNFGK

BAZ2B

1091

Q9UIF8
GLCIALFSSSMRNVQ

ABCA6

41

Q8N139
MVSQGLRCLKNSATS

A2ML1

1116

A8K2U0
DKRSASNAFMICGIL

ADGRL3

306

Q9HAR2
FGQMECLKLIASSRF

AP1G2

66

O75843
AGLLALSSMKSLCSL

CMIP

726

Q8IY22
ALCTRLAIMVNGSFK

ABCA13

4921

Q86UQ4
DLCLSMASFLKGITA

ACOT6

236

Q3I5F7
KSRLQLLGATCMFVA

CCND1

96

P24385
LGDTGSDMNKFCRSR

CEP78

81

Q5JTW2
RTKGFSLESCRSMVN

CAPN1

581

P07384
QAAFNLKMRAACTGR

BBOF1

386

Q8ND07
RLGQAQGSLSFCMLE

ENG

171

P17813
GIRMSFQNLLAKICF

AP3D1

1076

O14617
ATRCDFTLSKTNMAR

CPXM2

711

Q8N436
SQMSSDARGLLKSIC

NWD1

376

Q149M9
RASLRKCSVMFIGSL

MROH7

1211

Q68CQ1
CLKLASRAAFQGAMK

RAI1

1301

Q7Z5J4
CFLSSGFKLGRKMIQ

RAD21L1

366

Q9H4I0
MTSCEDINFLGFTKR

PATE2

81

Q6UY27
LSERSISFNGCLLQM

OR6K2

86

Q8NGY2
AVGKSSFLMRLCKNE

RASEF

551

Q8IZ41
SGLTGAKLQDCMSRA

EXOSC8

241

Q96B26
SMLTVKLFGIACATN

PIK3C2G

556

O75747
GRQKMTSLSSCFAQL

GOPC

66

Q9HD26
LADFGSCLRLNTNGM

CDC42BPG

211

Q6DT37
GSVNACEKTSFMFLR

PDK1

66

Q15118
FCNFTQRIEKGLMTA

KIAA1549

1061

Q9HCM3
RCLMTHNKGVSFSLA

LY6G6F

201

Q5SQ64
MKDFVRLQSSFLLCT

OOSP3

1

A0A2R8YFM6
GRAMFLVAKCQVASA

ANAPC5

661

Q9UJX4
LRCISEMNRLFSGKA

FBXW10B

231

O95170
ALLQTRKNCSMFIGS

ANKRD31

106

Q8N7Z5
ALLAGVSTQAFCSMK

OTOA

466

Q7RTW8
GACMSLLSVRVFFKK

EPHB1

181

P54762
NFTRCGLMLTLATNL

OTOP3

226

Q7RTS5
KTITLLGCATQMAFF

OR10W1

81

Q8NGF6
MSVFKLACADTRLNQ

OR2A12

181

Q8NGT7
ASQMSFCELFKDIGR

KIAA0895

396

Q8NCT3
GLSMLQDSGATLCRN

EURL

171

Q9NYK6
LLTKFQSSRMDDQRC

GPSM1

501

Q86YR5
EKLLNDGFSMLLRAC

MMS22L

646

Q6ZRQ5
NLRTIAKSGTKACME

HSP90AB3P

101

Q58FF7
ACRANVKSGAIMSAL

PPFIA4

851

O75335
AKMDNGEACFILSSR

KCNT1

426

Q5JUK3
MRLLEKLCSSAAGSS

C2CD4B

1

A6NLJ0
SNLVCKVSDFGMSRV

EPHA4

756

P54764
ICMFLQRAGKNKSSL

FSIP2

861

Q5CZC0
SSFLVDCSKAGSNML

FLNB

2531

O75369
LSRLMQCVSSFSKNG

EXOC2

836

Q96KP1
MVLQRNSCAKDLTSF

MKNK2

381

Q9HBH9
DKIAISLSACMGQLF

OR4A16

86

Q8NH70
ACIVKMGLSSVLRSA

OR51G1

141

Q8NGK1
RMLVAASLACAFTNA

OR3A2

151

P47893
LQKMSFSRLVCDNTR

LPO

661

P22079
LMSLSLSFLICNKGR

FAM223A

21

Q8IWN6
LRFSNGLMVTCSKDR

FBXW11

326

Q9UKB1
LLDGMTCNLRAKSFS

DCSTAMP

121

Q9H295
KKFQVTMRGLLSCLS

FBXO39

106

Q8N4B4
TKLRMELQVSSGFVC

FCER2

146

P06734
LKEEFRLAMALSGCQ

HAO1

336

Q9UJM8
FRSISRSLMLCNAKT

IL16

16

Q14005
RSLMLCNAKTSDDGS

IL16

21

Q14005
CILGRLSEKSSGQMA

KIF20B

96

Q96Q89
LSLCDLAGSERTMKT

KIF20B

376

Q96Q89
CLSKRLNSIRSFEMN

OBI1

506

Q5W0B1
VLFMLLNAKGTTVCT

DIP2B

1006

Q9P265
SSQGCDAFLRHKMTL

KDM4B

231

O94953
AMSNACKELAIFLTT

LEPROTL1

61

O95214
CRANVKSGAIMSALS

PPFIA1

901

Q13136
NLGNCSTTAMKLFDD

LNPEP

831

Q9UIQ6
MRTFVSGACDASSKL

GNB4

196

Q9HAV0
LMSLRKTAECGATVF

GDPD2

241

Q9HCC8
FRNRGMTALLKVSSC

F8

716

P00451
LCSIFGSNKDLMGLA

NLRP2

691

Q9NX02
TKLLRSSVLGFACKM

ENPEP

741

Q07075
ADMIFLRTSEKNGSC

ATP9A

171

O75110
ESCFSDRGSLKSIMQ

CDC42BPB

406

Q9Y5S2
MATATLKRNSGTCLF

CDC42BPB

1331

Q9Y5S2
CLSREAGGNMSIQFL

PCCA

616

P05165
GCLFIDKMDSRTFTN

PDF

221

Q9HBH1
VCSSKMGALSTERLQ

PLA2G4F

426

Q68DD2
LALSAKGRLMTCSLD

FAAP100

421

Q0VG06
RAKQSISFFLQLSMC

GPR55

261

Q9Y2T6
TSSMFTGDLECQKLL

KLHL4

386

Q9C0H6
KRGSMCNTLFSDAIL

OTULINL

221

Q9NUU6
TICRFEGLQLSFKNM

POU3F4

231

P49335
AMLQRFSGQSKARCI

GCKR

521

Q14397
FKANGFMALRNSLCL

OR56B2P

151

Q8NGI1
LRSSCLRGMNLASFF

ABCC4

311

O15439
NEKRMRLLQFVTGTC

ITCH

821

Q96J02
LGSLMKSCNLEIFRA

PRAMEF12

66

O95522
GVSKSDLLCFLTALM

OTOP1

86

Q7RTM1
SRKNIISFTGCMTQL

OR8B12

86

Q8NGG6
NKSISFLGCATQMFL

OR5T1

101

Q8NG75
KMALLASNSCFIRCN

FRG1

146

Q14331
ALRLNTMSKFTFTDC

DYNC2H1

1901

Q8NCM8
LQSAMALFACKTLGL

DYNC2H1

3686

Q8NCM8
SLMQCAGESITLFKN

ATM

751

Q13315
QCSLFSVMELARLKS

CNPPD1

391

Q9BV87
MSACGRKALTLLSSV

CACNG5

1

Q9UF02
VLCGMSSDERKAFLQ

HECTD1

2526

Q9ULT8
AVTLKCNFKTDGRMR

IGSF21

41

Q96ID5
KIADFLNSFDMSCRS

BRK1

31

Q8WUW1
MRICSFNVRSFGESK

DNASE1L3

21

Q13609
SFLCSTKLTQNGDML

DOCK4

571

Q8N1I0
DSRLMCSSVQKALFE

CCDC3

181

Q9BQI4
TESRSRLCMGSQKLL

FRMPD1

1456

Q5SYB0
SLMTLDSLQKCIFSF

CYP4F8

196

P98187
SLMTLDSLQKCIFSF

CYP4F12

196

Q9HCS2
QAFSRISGNVCLDMK

HEATR4

651

Q86WZ0
DCVMGSFKNQTFLIS

BMP6

261

P22004
SSRGFLDKMLCGNSL

CATIP

91

Q7Z7H3
MKTNFFGTRDVCTEL

CBR1

111

P16152
SESLMCKIADFGLAR

LYN

376

P07948
CFSFMASKAVNGRTI

FBXO47

336

Q5MNV8
FKNQMSTIAGDCLLS

DYNC1H1

3496

Q14204
GFAISAALLMACSLQ

SLC2A9

146

Q9NRM0
RLFCMGDVNAKASQT

KANK3

681

Q6NY19
EGICLSQASKLGLMS

GPR63

281

Q9BZJ6
IFLSMTSILQRGCSK

HGSNAT

321

Q68CP4
ELRKCAFISQASATM

FAH

101

P16930
LKCLAMINRFQFVSG

ELP2

441

Q6IA86
SCRIINTFLKTSGGM

DNAAF5

721

Q86Y56
FQRGLKRLSGAMCTS

GPR21

311

Q99679
LVSKCGINFSSLRKM

SLC15A2

366

Q16348
RLLNSGGAMEFTICK

CARD11

991

Q9BXL7
RFKRLACMFGSAVQS

CDH19

756

Q9H159
QLDKSMCSQFSFRAG

C4orf51

56

C9J302
MFLAQRSLCSLSGRA

KYAT3

1

Q6YP21
RKTGTRNMFSICSAV

MFSD5

401

Q6N075
CRANVKSGAIMSALS

PPFIA2

921

O75334
IQIGDTFRLSFCMSN

OR5B17

156

Q8NGF7
KCQVGFSSSDLVMRA

ISL2

91

Q96A47
IFMSERKSISFIGCA

OR13D1

116

Q8NGV5
KSAMGISFRSFCIIL

OR52H1

151

Q8NGJ2
GSDICFMQKIKASRS

PKP1

141

Q13835
MNKILSSTVCFGLLT

UTS2B

1

Q765I0
AFGLLCRMADQTFIS

NR5A1

261

Q13285
NMCGLLSIFTKVLSD

THADA

226

Q6YHU6
GRKQSLLICMSVNGF

SV2C

216

Q496J9
ALLLFSMVTKFCSGL

STRIP2

246

Q9ULQ0
LTGSTRSSFRKMCLQ

TOP6BL

406

Q8N6T0
RSSFRKMCLQTLQAA

TOP6BL

411

Q8N6T0
KLFLLNSVGQEMSRC

SYT16

546

Q17RD7
ILLTLNGCVDFMSKN

TEDDM1

76

Q5T9Z0
SQCLGSQRAFMKEGL

TOGARAM2

386

Q6ZUX3
FSFPCRQMSIDKGTL

HKDC1

601

Q2TB90
MACLLSSLKANGSRG

OGA

861

O60502
VCVQNKLGSMFLSET

PLCE1

956

Q9P212
LKLCADFKRTGMDSN

TAF1

846

P21675
AAFLMGINSSELVKC

MYH15

396

Q9Y2K3
SQMRNLRKLFISDGC

PRAMEF22

231

A3QJZ6
RNSMKVFLKQGECAS

SEMA4B

741

Q9NPR2
RESAKLAMICSGVSL

SLCO5A1

501

Q9H2Y9
FSLGLTQMNCETIKS

SHOC1

1231

Q5VXU9
RMLLKRGCNVNSTSS

PLA2G6

301

O60733
SSKAARSGLRMCDLV

ADSS2

171

P30520
EKLFDFLGSLLTMCS

HERC2P3

811

Q9BVR0
RNFSCLAVLDLMSRG

ICAM2

186

P13598
CNSSRSFMDLKALLS

NIF3L1

21

Q9GZT8
LRMNSAGRQKAFSTC

OR8K3

226

Q8NH51
SRQRNCFFALSVKMA

SOCS1

106

O15524
GNLLASCSDDMTLKI

TBL1XR1

361

Q9BZK7
AAMAGLAFTCLKRSN

TCN2

196

P20062
IECFMTRTSKGNRIA

ABHD17B

66

Q5VST6
DICLSMASFLKNVSA

ACOT4

236

Q8N9L9
AASLALGKFCMISAT

NCAPD2

1036

Q15021
NMEELLNLCSGKFTS

CLSPN

936

Q9HAW4
MLRSNLIGCVSNDTF

SLIT3

611

O75094
RKCGKAFNQMSSLLL

ZNF667

256

Q5HYK9
SGSCSAEDLKMARSL

TFDP1

311

Q14186
CGKAFMRSSSLIIHQ

ZNF624

561

Q9P2J8
RAQGMATLVFSRSCK

TEX13D

606

A0A0J9YY54
TASFTTKIGLCVNMR

TTLL8

161

A6PVC2
FLGCFSDLRKISAMN

WDFY3

721

Q8IZQ1
CVLTFKLNIFLTGMN

TMTC1

96

Q8IUR5
AGAIRLAMAKALCSF

MRPS9

341

P82933
MSKARQLEGKSCSLV

SPIDR

536

Q14159
FLCSMFVNSLLLSKE

WDR75

746

Q8IWA0
QILGGFLVSKFRMTC

SLCO4C1

436

Q6ZQN7
SNRRFVLCGTNVKAM

STAT4

371

Q14765
LAMRSFGENDALKTC

RLIM

556

Q9NVW2
LCSSKDDGQALMILS

TBC1D8

711

O95759
MSQFLCLKNIRTFLS

VAV1

66

P15498
TTSCKACQMLLRGTF

VAV1

526

P15498
TRRCNGFKMFLAALS

SLCO1B3

21

Q9NPD5
TMQGHTGRLLKSLCF

PIEZO2

51

Q9H5I5
ILKLSNGARCSMNTE

UBE2O

221

Q9C0C9
MNSNLGITAACKLRF

TDP2

301

O95551
QSCLQILGFLDSMAS

WDFY4

761

Q6ZS81
KFLSFMNLTCAVGTT

WAPL

1161

Q7Z5K2
REQFKLGVKCMSTSA

TLNRD1

211

Q9H1K6
LSTTMSRCAKDLFGF

PKD2

586

Q13563
LAMNLCTFISAASKF

SLC66A3

116

Q8N755
SGSCSAEDLKMARNL

TFDP3

306

Q5H9I0
MAKDNSTVRCFQGLL

UPK1B

1

O75841
ACRKSVMIGTALNTS

PMS2

811

P54278
GLSSLLCNFTKSMEE

PRKDC

226

P78527
LASSARTLALQCAMK

ZSWIM6

976

Q9HCJ5
NECGKAFTRKSALRM

ZNF41

456

P51814
GKAFSQCSLLNLHMR

ZNF569

556

Q5MCW4
CLRDDSGRMALSKTF

TSSK1B

161

Q9BXA7
ANLSRKAVSDMLTAC

TLN2

2206

Q9Y4G6
VMNKSRCESLLFNES

SCN7A

1101

Q01118
MCYRKSLQLASQRGS

TTC37

1421

Q6PGP7
RDVTMFFQKISLGDC

ULBP1

176

Q9BZM6
CFDLTGQTRRLKMDA

THAP2

61

Q9H0W7
KECGIAFMNSSSLLN

ZNF485

161

Q8NCK3
SQLFGTLMILKSACS

TRRAP

2266

Q9Y4A5
RSETMCLAQLFLQSG

ATP6V0A2

6

Q9Y487
LAAGFCSDKMSLLLV

WDR43

336

Q15061
KMRLSTCFNAFIAGI

UNC79

1331

Q9P2D8
CKAMSQGLVTFRDVA

ZNF527

6

Q8NB42
MSQFLCLKNIRTFLT

VAV3

66

Q9UKW4
CMNCGKSFSRVSLLI

ZNF302

366

Q9NR11
ILETAKRQMFSLCGT

KLHL38

251

Q2WGJ6
KTCSPGMNSFLIFAR

LRP4

1041

O75096
SRMSKCSRFLNDTSL

MYO1B

491

O43795
LGIFQTMNLTSLCEK

NLRP13

86

Q86W25
GSNLLSICKTAEFQM

PLP1

221

P60201