Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-diphosphoinositol pentakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	2.49e-06	2	32	2	GO:0033857
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	7.46e-06	3	32	2	GO:0018858
GeneOntologyMolecularFunction	inositol hexakisphosphate 3-kinase activity	PPIP5K1 PPIP5K2	1.49e-05	4	32	2	GO:0052724
GeneOntologyMolecularFunction	inositol hexakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.49e-05	4	32	2	GO:0052723
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	1.49e-05	4	32	2	GO:0102391
GeneOntologyMolecularFunction	AMPA glutamate receptor activity	GRIA1 GRIA3	1.49e-05	4	32	2	GO:0004971
GeneOntologyMolecularFunction	inositol hexakisphosphate 5-kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000832
GeneOntologyMolecularFunction	diphosphoinositol pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000829
GeneOntologyMolecularFunction	inositol hexakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000828
GeneOntologyMolecularFunction	inositol-1,3,4,5,6-pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000827
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	6.92e-05	8	32	2	GO:0004321
GeneOntologyMolecularFunction	glutamate-gated calcium ion channel activity	GRIA1 GRIA3	6.92e-05	8	32	2	GO:0022849
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSM2B	1.36e-04	11	32	2	GO:0031956
GeneOntologyMolecularFunction	inositol phosphate kinase activity	PPIP5K1 PPIP5K2	1.36e-04	11	32	2	GO:0180030
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIA1 GRIA3	3.33e-04	17	32	2	GO:0004970
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 ACSM2A MYO7A ATP2A2 KIF26B ACSM2B	3.78e-04	614	32	6	GO:0140657
GeneOntologyMolecularFunction	C-acyltransferase activity	ACSM2A ACSM2B	5.13e-04	21	32	2	GO:0016408
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	GRIA1 GRIA3 SLC6A14	6.27e-04	105	32	3	GO:0015171
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA1 GRIA3	6.72e-04	24	32	2	GO:0099507
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSM2A ACSM2B	7.89e-04	26	32	2	GO:0015645
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	GRIA1 GRIA3 ATP2A2 SLC4A11 SLC6A14	8.03e-04	465	32	5	GO:0046873
GeneOntologyMolecularFunction	CoA-ligase activity	ACSM2A ACSM2B	8.52e-04	27	32	2	GO:0016405
GeneOntologyMolecularFunction	glutamate receptor activity	GRIA1 GRIA3	8.52e-04	27	32	2	GO:0008066
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH3 MYO7A KIF26B	8.81e-04	118	32	3	GO:0003774
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSM2A ACSM2B	1.12e-03	31	32	2	GO:0016878
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	GRIA1 GRIA3	1.12e-03	31	32	2	GO:0099604
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	GRIA1 GRIA3 SLC4A11 SLC6A14	1.18e-03	293	32	4	GO:0008514
GeneOntologyMolecularFunction	spectrin binding	ANK3 MYO7A	1.35e-03	34	32	2	GO:0030507
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	GRIA1 GRIA3 ATP2A2	1.79e-03	151	32	3	GO:0015085
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSM2A ACSM2B	1.96e-03	41	32	2	GO:0016877
GeneOntologyMolecularFunction	phosphotransferase activity, phosphate group as acceptor	PPIP5K1 PPIP5K2	1.96e-03	41	32	2	GO:0016776
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	GRIA1 GRIA3 ATP2A2 SLC4A11 SLC6A14	3.00e-03	627	32	5	GO:0022890
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GRIA1 GRIA3	3.76e-03	57	32	2	GO:1904315
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	GRIA1 GRIA3 ATP2A2 SLC4A11 SLC6A14	3.83e-03	664	32	5	GO:0008324
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GRIA1 GRIA3	4.16e-03	60	32	2	GO:0099529
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	GRIA1 GRIA3 SLC6A14	4.36e-03	207	32	3	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	GRIA1 GRIA3 SLC6A14	4.42e-03	208	32	3	GO:0005342
GeneOntologyMolecularFunction	transmitter-gated channel activity	GRIA1 GRIA3	4.86e-03	65	32	2	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GRIA1 GRIA3	4.86e-03	65	32	2	GO:0022824
GeneOntologyMolecularFunction	microtubule motor activity	DNAH3 KIF26B	5.61e-03	70	32	2	GO:0003777
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GRIA1 GRIA3	6.42e-03	75	32	2	GO:0098960
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GRIA1 GRIA3 ATP2A2 SLC4A11 SLC6A14	6.69e-03	758	32	5	GO:0015318
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GRIA1 GRIA3	6.75e-03	77	32	2	GO:0005230
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GRIA1 GRIA3 ATP2A2 SLC4A11 SLC6A14	8.06e-03	793	32	5	GO:0015075
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	USP34 ATG4C	8.36e-03	86	32	2	GO:0004197
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GRIA1 GRIA3	1.12e-02	100	32	2	GO:0030594
GeneOntologyMolecularFunction	amyloid-beta binding	GRIA1 GRIA3	1.16e-02	102	32	2	GO:0001540
Domain	Acid_Pase_AS	PPIP5K1 PPIP5K2	4.25e-05	6	32	2	IPR033379
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PPIP5K2	5.94e-05	7	32	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PPIP5K2	5.94e-05	7	32	2	PS00616
Domain	His_Pase_clade-2	PPIP5K1 PPIP5K2	7.91e-05	8	32	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PPIP5K2	7.91e-05	8	32	2	PF00328
Domain	AMP-bd_C	ACSM2A ACSM2B	3.81e-04	17	32	2	IPR025110
Domain	AMP-binding_C	ACSM2A ACSM2B	3.81e-04	17	32	2	PF13193
Domain	Iontro_rcpt	GRIA1 GRIA3	4.28e-04	18	32	2	IPR001320
Domain	Lig_chan	GRIA1 GRIA3	4.28e-04	18	32	2	PF00060
Domain	Lig_chan-Glu_bd	GRIA1 GRIA3	4.28e-04	18	32	2	PF10613
Domain	PBPe	GRIA1 GRIA3	4.28e-04	18	32	2	SM00079
Domain	Iono_rcpt_met	GRIA1 GRIA3	4.28e-04	18	32	2	IPR001508
Domain	Glu/Gly-bd	GRIA1 GRIA3	4.28e-04	18	32	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIA1 GRIA3	4.28e-04	18	32	2	SM00918
Domain	His_PPase_superfam	PPIP5K1 PPIP5K2	5.30e-04	20	32	2	IPR029033
Domain	-	PPIP5K1 PPIP5K2	5.30e-04	20	32	2	3.40.50.1240
Domain	AMP-binding_CS	ACSM2A ACSM2B	9.01e-04	26	32	2	IPR020845
Domain	AMP_BINDING	ACSM2A ACSM2B	1.05e-03	28	32	2	PS00455
Domain	AMP-binding	ACSM2A ACSM2B	1.20e-03	30	32	2	PF00501
Domain	AMP-dep_Synth/Lig	ACSM2A ACSM2B	1.20e-03	30	32	2	IPR000873
Domain	ANF_receptor	GRIA1 GRIA3	1.82e-03	37	32	2	PF01094
Domain	ANF_lig-bd_rcpt	GRIA1 GRIA3	1.82e-03	37	32	2	IPR001828
Domain	Peripla_BP_I	GRIA1 GRIA3	2.03e-03	39	32	2	IPR028082
Domain	IQ	IQCH MYO7A	8.47e-03	81	32	2	SM00015
Domain	IQ_motif_EF-hand-BS	IQCH MYO7A	1.04e-02	90	32	2	IPR000048
Domain	IQ	IQCH MYO7A	1.10e-02	93	32	2	PS50096
Pathway	REACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE	ACSM2A ACSM2B	4.51e-05	6	25	2	MM14693
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	6.31e-05	7	25	2	MM14598
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	1.08e-04	9	25	2	M26968
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	PPIP5K1 PPIP5K2	1.35e-04	10	25	2	M27051
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	PPIP5K1 PPIP5K2	1.35e-04	10	25	2	MM14709
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA1 GRIA3	3.57e-04	16	25	2	MM15048
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA1 GRIA3	4.04e-04	17	25	2	M5488
Pathway	WP_NRXN1_DELETION_SYNDROME	GRIA1 GRIA3	4.54e-04	18	25	2	M48098
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA1 GRIA3	5.63e-04	20	25	2	MM15485
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA1 GRIA3	6.21e-04	21	25	2	M27736
Pathway	REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION	GRIA1 GRIA3	6.21e-04	21	25	2	M838
Pathway	WP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA	GRIA1 GRIA3	6.82e-04	22	25	2	M39795
Pathway	REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION	GRIA1 GRIA3	6.82e-04	22	25	2	MM15104
Pathway	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	GRIA1 GRIA3	1.19e-03	29	25	2	MM15028
Pathway	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	GRIA1 GRIA3	1.36e-03	31	25	2	M7223
Pathway	KEGG_BUTANOATE_METABOLISM	OXCT2 ACSM2A	1.64e-03	34	25	2	M3397
Pathway	REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS	GRIA1 GRIA3	1.73e-03	35	25	2	MM15109
Pathway	WP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION	GRIA1 GRIA3	2.37e-03	41	25	2	M39655
Pathway	REACTOME_ASPIRIN_ADME	ACSM2A ACSM2B	2.73e-03	44	25	2	M45014
Pathway	REACTOME_ASPIRIN_ADME	ACSM2A ACSM2B	2.85e-03	45	25	2	MM15694
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	PPIP5K1 PPIP5K2	3.24e-03	48	25	2	MM14589
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	PPIP5K1 PPIP5K2	3.24e-03	48	25	2	M26964
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	8.20e-07	2	32	2	19634011
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	8.20e-07	2	32	2	16521160
Pubmed	Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3.	GRIA1 GRIA3	8.20e-07	2	32	2	27708157
Pubmed	Synaptic plasticity through activation of GluA3-containing AMPA-receptors.	GRIA1 GRIA3	8.20e-07	2	32	2	28762944
Pubmed	Distinct effects of AMPAR subunit depletion on spatial memory.	GRIA1 GRIA3	8.20e-07	2	32	2	37876813
Pubmed	Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	18981179
Pubmed	Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility.	GRIA1 GRIA3	8.20e-07	2	32	2	20579352
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	8.20e-07	2	32	2	29948332
Pubmed	Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3.	GRIA1 GRIA3	8.20e-07	2	32	2	28103481
Pubmed	A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning.	GRIA1 GRIA3	8.20e-07	2	32	2	17928436
Pubmed	The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	28126903
Pubmed	Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	17690096
Pubmed	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	17702752
Pubmed	NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.	GRIA1 GRIA3	2.46e-06	3	32	2	36070750
Pubmed	PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.	PPIP5K1 PPIP5K2	2.46e-06	3	32	2	31852976
Pubmed	An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.	GRIA1 GRIA3	2.46e-06	3	32	2	32569783
Pubmed	Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.	GRIA1 GRIA3	2.46e-06	3	32	2	36223737
Pubmed	Persistent synaptic scaling independent of AMPA receptor subunit composition.	GRIA1 GRIA3	2.46e-06	3	32	2	23864664
Pubmed	AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.	GRIA1 GRIA3	2.46e-06	3	32	2	34426577
Pubmed	AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy.	GRIA1 GRIA3	2.46e-06	3	32	2	15145077
Pubmed	Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain.	GRIA1 GRIA3	2.46e-06	3	32	2	28290985
Pubmed	Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.	GRIA1 GRIA3	2.46e-06	3	32	2	26585043
Pubmed	Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.	GRIA1 GRIA3	2.46e-06	3	32	2	14687553
Pubmed	Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2.	GRIA1 GRIA3	2.46e-06	3	32	2	29180434
Pubmed	Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.	GRIA1 GRIA3	2.46e-06	3	32	2	15144856
Pubmed	Synaptic AMPA receptor plasticity and behavior.	GRIA1 GRIA3	2.46e-06	3	32	2	19217372
Pubmed	Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.	GRIA1 GRIA3	2.46e-06	3	32	2	19409270
Pubmed	Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.	GRIA1 GRIA3	2.46e-06	3	32	2	12700243
Pubmed	Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1.	GRIA1 GRIA3	2.46e-06	3	32	2	21135237
Pubmed	Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.	GRIA1 GRIA3	2.46e-06	3	32	2	12172541
Pubmed	Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting.	GRIA1 GRIA3	2.46e-06	3	32	2	28630296
Pubmed	LTP requires a reserve pool of glutamate receptors independent of subunit type.	GRIA1 GRIA3	2.46e-06	3	32	2	23235828
Pubmed	A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.	GRIA1 GRIA3	4.92e-06	4	32	2	10688364
Pubmed	Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit.	GRIA1 GRIA3	4.92e-06	4	32	2	29515177
Pubmed	Chromosomal localization of human glutamate receptor genes.	GRIA1 GRIA3	4.92e-06	4	32	2	1319477
Pubmed	AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.	GRIA1 GRIA3	4.92e-06	4	32	2	12692557
Pubmed	GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.	GRIA1 GRIA3	4.92e-06	4	32	2	26932439
Pubmed	Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.	GRIA1 GRIA3	4.92e-06	4	32	2	12125045
Pubmed	AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.	GRIA1 GRIA3	4.92e-06	4	32	2	9221927
Pubmed	Interaction proteomics reveals brain region-specific AMPA receptor complexes.	GRIA1 GRIA3	4.92e-06	4	32	2	25337787
Pubmed	Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.	GRIA1 GRIA3	4.92e-06	4	32	2	17828255
Pubmed	Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.	GRIA1 GRIA3	4.92e-06	4	32	2	31231192
Pubmed	The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.	GRIA1 GRIA3	4.92e-06	4	32	2	24652293
Pubmed	Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.	GRIA1 GRIA3	4.92e-06	4	32	2	17409242
Pubmed	The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function.	GRIA1 GRIA3	4.92e-06	4	32	2	23664612
Pubmed	Expression and Interaction Proteomics of GluA1- and GluA3-Subunit-Containing AMPARs Reveal Distinct Protein Composition.	GRIA1 GRIA3	4.92e-06	4	32	2	36429079
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	4.92e-06	4	32	2	32830538
Pubmed	The Role of AMPARs in the Maturation and Integration of Caudal Ganglionic Eminence-Derived Interneurons into Developing Hippocampal Microcircuits.	GRIA1 GRIA3	4.92e-06	4	32	2	30931998
Pubmed	AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity.	GRIA1 GRIA3	4.92e-06	4	32	2	31992779
Pubmed	Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.	GRIA1 GRIA3	4.92e-06	4	32	2	19295509
Pubmed	LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.	GRIA1 GRIA3	4.92e-06	4	32	2	29581259
Pubmed	AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.	GRIA1 GRIA3	4.92e-06	4	32	2	19004011
Pubmed	Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development.	GRIA1 GRIA3	4.92e-06	4	32	2	12414093
Pubmed	Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.	GRIA1 GRIA3	4.92e-06	4	32	2	14561864
Pubmed	Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.	GRIA1 GRIA3	4.92e-06	4	32	2	32831170
Pubmed	AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.	GRIA1 GRIA3	4.92e-06	4	32	2	9648857
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	USP34 ANK3 MYO7A ATP2A2	5.81e-06	128	32	4	30995482
Pubmed	Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.	GRIA1 GRIA3	8.19e-06	5	32	2	9482932
Pubmed	Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission.	GRIA1 GRIA3	8.19e-06	5	32	2	31492534
Pubmed	Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.	GRIA1 GRIA3	8.19e-06	5	32	2	16129400
Pubmed	Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival.	GRIA3 MYO7A	1.23e-05	6	32	2	33015071
Pubmed	Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior.	GRIA1 GRIA3	1.23e-05	6	32	2	28194005
Pubmed	Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere.	FHL2 ATP2A2	1.23e-05	6	32	2	38569934
Pubmed	Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways.	GRIA1 GRIA3	1.23e-05	6	32	2	30057205
Pubmed	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	ANK3 PTGFR	1.23e-05	6	32	2	22182935
Pubmed	Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.	GRIA1 GRIA3	1.72e-05	7	32	2	17093100
Pubmed	CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus.	GRIA1 GRIA3	1.72e-05	7	32	2	20185686
Pubmed	TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.	GRIA1 GRIA3	1.72e-05	7	32	2	27076426
Pubmed	Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.	GRIA1 GRIA3	1.72e-05	7	32	2	21368048
Pubmed	Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.	GRIA1 GRIA3	1.72e-05	7	32	2	33981040
Pubmed	Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.	GRIA1 GRIA3	1.72e-05	7	32	2	10407040
Pubmed	Glutamate receptors in cortical plasticity: molecular and cellular biology.	GRIA1 GRIA3	1.72e-05	7	32	2	9016303
Pubmed	Glutamate receptors: brain function and signal transduction.	GRIA1 GRIA3	1.72e-05	7	32	2	9651535
Pubmed	AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein.	GRIA1 ANK3	2.29e-05	8	32	2	28821923
Pubmed	Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.	GRIA1 GRIA3	2.29e-05	8	32	2	21172611
Pubmed	Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.	GRIA1 GRIA3	2.29e-05	8	32	2	23217150
Pubmed	Expression of glutamate receptor subunit genes during development of the mouse retina.	GRIA1 GRIA3	2.94e-05	9	32	2	9051806
Pubmed	Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.	GRIA1 GRIA3	2.94e-05	9	32	2	24292102
Pubmed	Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells.	GRIA3 MYO7A	3.67e-05	10	32	2	23385583
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GRIA1 ATG4C GRIA3 PPIP5K2 ATP2A2 PTGFR SLC4A11 SLC6A14	3.70e-05	1442	32	8	35575683
Pubmed	A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.	BBIP1 USP34 KIF26B ATXN7L1	3.70e-05	205	32	4	12040188
Pubmed	Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4.	AP4E1 GRIA1	4.49e-05	11	32	2	18341993
Pubmed	The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.	GRIA1 GRIA3	5.38e-05	12	32	2	11891216
Pubmed	Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.	GRIA1 GRIA3	6.36e-05	13	32	2	20859245
Pubmed	Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.	GRIA1 GRIA3	6.36e-05	13	32	2	25218043
Pubmed	Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.	GRIA1 GRIA3	8.55e-05	15	32	2	9481670
Pubmed	PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.	GRIA1 GRIA3	9.76e-05	16	32	2	16055064
Pubmed	Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood.	GRIA1 GRIA3	1.11e-04	17	32	2	32185508
Pubmed	BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.	GRIA1 GRIA3	1.24e-04	18	32	2	12588844
Pubmed	Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.	GRIA1 GRIA3	1.24e-04	18	32	2	18311135
Pubmed	Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice.	GRIA1 GRIA3	1.24e-04	18	32	2	34455539
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	GRIA1 GRIA3	1.24e-04	18	32	2	14730302
Pubmed	Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.	GRIA1 GRIA3	2.05e-04	23	32	2	8464923
Pubmed	Glutamate can act as a signaling molecule in mouse preimplantation embryos†.	GRIA1 GRIA3	2.24e-04	24	32	2	35746896
Pubmed	High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.	GRIA1 GRIA3	2.24e-04	24	32	2	22632720
Pubmed	Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.	ACSM2A ACSM2B	2.43e-04	25	32	2	19372376
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	AP4E1 GRIA1 ZHX3 TSC22D2 SEMA3E	3.81e-04	686	32	5	29987050
Pubmed	Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum.	GRIA1 SEMA3E	4.25e-04	33	32	2	18199763
Pubmed	HIV-1 subtypes B and C Tat differentially impact synaptic plasticity expression and implicates HIV-associated neurocognitive disorders.	GRIA1 GRIA3	5.65e-04	38	32	2	25613138
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	GRIA3 MBD5	7.57e-04	44	32	2	32492419
Interaction	ACSM2A interactions	ACSM2A ACSM2B	1.46e-05	4	32	2	int:ACSM2A
Interaction	ACSM2B interactions	ACSM2A ACSM2B	1.46e-05	4	32	2	int:ACSM2B
Cytoband	16p12.3	DNAH3 ACSM2A ACSM2B	1.81e-06	34	32	3	16p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	DNAH3 ACSM2A ACSM2B	2.37e-04	172	32	3	chr16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr3q25	TSC22D2 TRIM59	7.02e-03	180	32	2	chr3q25
Cytoband	Ensembl 112 genes in cytogenetic band chr1p31	ATG4C PTGFR	1.07e-02	224	32	2	chr1p31
GeneFamily	Glutamate ionotropic receptor AMPA type subunits	GRIA1 GRIA3	8.47e-06	4	22	2	1200
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSM2B	4.51e-04	26	22	2	40
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	ZHX3 ANK3 MBD5 ACSM2A ACSM2B	6.81e-06	221	32	5	M39222
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	ZHX3 ACSM2A ATP2A2 KIF26B ATXN7L1 ACSM2B	9.99e-06	417	32	6	M39224
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	ANK3 MBD5 ACSM2A ACSM2B	6.10e-05	176	32	4	M39223
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	USP34 GRIA1 ZHX3 ANK3 FHL2 PTGFR TRIM59 HCK	2.18e-05	819	32	8	gudmap_developingKidney_e15.5_Peripheral blastema_1000
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 MBD5 ACSM2A ATXN7L1 ACSM2B	2.46e-07	192	32	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	P03-Epithelial-alveolar_epithelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 HCK SLC6A14 SEMA3E	8.34e-06	181	32	4	c3dbf8850d3812fbb770798f4cf38908db8bb92b
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK3 FHL2 PTGFR KIF26B	1.14e-05	196	32	4	fd0a2b863dedaf08d18e7f67da18ac7e853991e4
ToppCell	distal-1-Endothelial-Lymphatic\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GRIA1 MYO7A LRIT3 ACSM2B	1.19e-05	198	32	4	b6fea363463c8dd7e6780c085ece4900266a6286
ToppCell	Club_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	FHL2 PTGFR SEMA3E	1.58e-04	147	32	3	9211242a8e40d50414d310940616eccce299a7f8
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IQCH ACSM2B SEMA3E	1.65e-04	149	32	3	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IQCH ACSM2B SEMA3E	1.65e-04	149	32	3	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	HCK SLC6A14 SEMA3E	1.68e-04	150	32	3	6a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPIP5K2 ANK3 HCK	2.22e-04	165	32	3	354978d4f35154d7b2e36e94de669e045adef512
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL2 CRISP1 SEMA3E	2.30e-04	167	32	3	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	Tuft-tuft-1\|World / Class top	MYO7A HCK SLC6A14	2.34e-04	168	32	3	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	ASK428-Epithelial-Secretory\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	PPIP5K1 FHL2 PTGFR	2.43e-04	170	32	3	9e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTGFR KIF26B SLC4A11	2.43e-04	170	32	3	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 MYO7A ATXN7L1	2.47e-04	171	32	3	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANK3 MYO7A SLC4A11	2.47e-04	171	32	3	b113fbebb89056af0b9c775d2fb6552206a80467
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK3 SLC6A14 SEMA3E	2.55e-04	173	32	3	45808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSC22D2 ANK3 PTGFR	2.55e-04	173	32	3	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	IIH-CD8-naive_CD4\|IIH / Condition, Cell_class and T cell subcluster	GRIA3 UTP20 PPIP5K1	2.55e-04	173	32	3	4f2843371d18af766c1892529ce286f56c956fde
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK3 SLC6A14 SEMA3E	2.55e-04	173	32	3	7fa9dbcb258c3ab974490063951620e2def03db1
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPIP5K1 ANK3 SEMA3E	2.60e-04	174	32	3	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP2A2 SLC4A11 SLC6A14	2.60e-04	174	32	3	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	Tuft-tuft-4\|World / Class top	SPIRE2 HCK SLC6A14	2.60e-04	174	32	3	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPIP5K1 ANK3 PTGFR	2.60e-04	174	32	3	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 FHL2 PTGFR	2.64e-04	175	32	3	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 FHL2 PTGFR	2.64e-04	175	32	3	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRIT3 TRIM59 SLC4A11	2.69e-04	176	32	3	0f056597bc9e53176ce8670924ac925c801964b5
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	ANK3 ACSM2A ACSM2B	2.69e-04	176	32	3	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRIT3 TRIM59 SLC4A11	2.69e-04	176	32	3	d04be5acf0be46adc3d2055f6f21358c02792817
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FHL2 SLC4A11 SLC6A14	2.78e-04	178	32	3	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FHL2 SLC4A11 SLC6A14	2.78e-04	178	32	3	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACSM2A KIF26B SLC4A11	2.78e-04	178	32	3	544379f5a6145429762258d426b876bb36c112f5
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FHL2 SLC4A11 SLC6A14	2.78e-04	178	32	3	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FHL2 SLC4A11 SLC6A14	2.78e-04	178	32	3	49a2271718637522f74334068d252963ee13b1ce
ToppCell	P15-Epithelial\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	2.82e-04	179	32	3	869d3d203e2cb88636e2f0c4476c72571ae3b5ca
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 SLC4A11 SLC6A14	2.82e-04	179	32	3	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIA3 ACSM2A ACSM2B	2.82e-04	179	32	3	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 ANK3 SEMA3E	2.87e-04	180	32	3	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GRIA1 ATG4C PTGFR	2.87e-04	180	32	3	e9785ac2806103f725f5a5208495826354ec6e22
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 ANK3 SEMA3E	2.87e-04	180	32	3	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	P03-Epithelial\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	2.91e-04	181	32	3	de0466072f5b2ab8db3d9bab31e3205d1ff7cfb7
ToppCell	P15-Epithelial-alveolar_epithelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	2.91e-04	181	32	3	7033be0ba90556f7e5f7c0d4a9f7644afcb22c9b
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 ANK3 SEMA3E	3.01e-04	183	32	3	876b4f128c2168fdae7488201ff44f19c06c8415
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 ANK3 SEMA3E	3.01e-04	183	32	3	b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	GRIA3 SPIRE2 FHL2	3.01e-04	183	32	3	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.01e-04	183	32	3	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 ANK3 SEMA3E	3.01e-04	183	32	3	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	P28-Epithelial\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	3.06e-04	184	32	3	05811d13bd8a602095a3fcf5e55345edadc7b8bf
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	ANK3 PTGFR SLC6A14	3.06e-04	184	32	3	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	GRIA3 SPIRE2 FHL2	3.06e-04	184	32	3	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSM2A MYO7A ACSM2B	3.11e-04	185	32	3	9de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell	P28-Epithelial-alveolar_epithelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	3.11e-04	185	32	3	5bb513e569f3a197d55ae2ca683e202daebabeac
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.11e-04	185	32	3	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSM2A MYO7A ACSM2B	3.11e-04	185	32	3	18f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA1 FHL2 SEMA3E	3.11e-04	185	32	3	872720275789d249c9859de825a923803d458875
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GRIA3 PTGFR KIF26B	3.16e-04	186	32	3	8915436d09775f2828a7678af203b1082b36e21c
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.16e-04	186	32	3	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	P15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HCK SLC6A14 SEMA3E	3.16e-04	186	32	3	521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 ACSM2A KIF26B	3.16e-04	186	32	3	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 ACSM2A ACSM2B	3.16e-04	186	32	3	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	Control-Epithelial-ATII\|World / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.16e-04	186	32	3	f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.21e-04	187	32	3	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 ANK3 SEMA3E	3.21e-04	187	32	3	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 ATP2A2 ACSM2B	3.21e-04	187	32	3	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL2 SLC4A11 SEMA3E	3.21e-04	187	32	3	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ATG4C MYO7A HCK	3.21e-04	187	32	3	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 ACSM2A ACSM2B	3.21e-04	187	32	3	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 ACSM2A ACSM2B	3.21e-04	187	32	3	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPIP5K1 ANK3 PTGFR	3.21e-04	187	32	3	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	P28-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HCK SLC6A14 SEMA3E	3.21e-04	187	32	3	a4b41904ba05eb76212c949fc3ac197f906c8351
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 FHL2 PTGFR	3.26e-04	188	32	3	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.26e-04	188	32	3	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	USP34 SPIRE2 KIF26B	3.26e-04	188	32	3	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	ANK3 PTGFR SLC6A14	3.31e-04	189	32	3	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	FHL2 SLC4A11 SLC6A14	3.31e-04	189	32	3	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	18-Airway-Epithelial-Submucosal_gland\|Airway / Age, Tissue, Lineage and Cell class	ANK3 SLC4A11 SLC6A14	3.31e-04	189	32	3	c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.31e-04	189	32	3	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRIA3 ACSM2A ACSM2B	3.31e-04	189	32	3	28b502611829e4a24caff2562545c7db97686099
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 ANK3 ACSM2B	3.31e-04	189	32	3	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSM2A KIF26B ACSM2B	3.31e-04	189	32	3	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.31e-04	189	32	3	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	PND10-Epithelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK3 SLC6A14 SEMA3E	3.31e-04	189	32	3	89349e226a5512833a94b1bf68056a6985fe4afd
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.36e-04	190	32	3	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.36e-04	190	32	3	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ACSM2A MYO7A ACSM2B	3.36e-04	190	32	3	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 PTGFR SLC6A14	3.36e-04	190	32	3	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.36e-04	190	32	3	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSM2A KIF26B ACSM2B	3.41e-04	191	32	3	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 ACSM2A ACSM2B	3.41e-04	191	32	3	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.41e-04	191	32	3	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 ACSM2A ACSM2B	3.41e-04	191	32	3	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 SLC6A14 SEMA3E	3.41e-04	191	32	3	402c341b00f98e8215458766b3c219fff8dcb447
ToppCell	P07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HCK SLC6A14 SEMA3E	3.41e-04	191	32	3	0f360766490bef3495c42f6421b22a988cfc68fb
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ANK3 PTGFR SLC6A14	3.41e-04	191	32	3	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	P03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HCK SLC6A14 SEMA3E	3.46e-04	192	32	3	be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ANK3 PTGFR SLC6A14	3.46e-04	192	32	3	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANK3 PTGFR SLC6A14	3.46e-04	192	32	3	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FHL2 SLC4A11 SEMA3E	3.46e-04	192	32	3	c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FHL2 SLC4A11 SEMA3E	3.46e-04	192	32	3	5d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANK3 FHL2 ATP2A2	3.46e-04	192	32	3	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PND03-Epithelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK3 SLC6A14 SEMA3E	3.46e-04	192	32	3	d8c23693f690d4d568585537bbfedda05d505b3d
Drug	5-fluorowillardiine	GRIA1 GRIA3	1.91e-06	2	32	2	ctd:C095178
Drug	3-pyridazinol 1-oxide	GRIA1 GRIA3	1.15e-05	4	32	2	CID000574311
Drug	AC1NUTWC	ACSM2A ACSM2B	1.15e-05	4	32	2	CID005460914
Drug	AC1L1YEG	GRIA1 GRIA3	1.91e-05	5	32	2	CID000063114
Drug	Chicago acid	GRIA1 GRIA3	1.91e-05	5	32	2	CID000065740
Drug	irampanel	GRIA1 GRIA3	1.91e-05	5	32	2	CID003038472
Drug	CHEBI:570577	GRIA1 GRIA3	1.91e-05	5	32	2	CID011334126
Drug	beta-N-oxalylaminoalanine	GRIA1 GRIA3	1.91e-05	5	32	2	CID000107978
Drug	LY395153	GRIA1 GRIA3	1.91e-05	5	32	2	CID000656707
Drug	5-h PCA	GRIA1 GRIA3	1.91e-05	5	32	2	CID000129091
Drug	1-BCP	GRIA1 GRIA3	1.91e-05	5	32	2	CID000001370
Drug	2cmo	GRIA1 GRIA3	2.86e-05	6	32	2	CID006914597
Drug	YM928	GRIA1 GRIA3	2.86e-05	6	32	2	CID006918393
Drug	4,6-dichloroindole-2-carboxylic acid	GRIA1 GRIA3	4.00e-05	7	32	2	CID000127988
Drug	thio-ATPA	GRIA1 GRIA3	4.00e-05	7	32	2	CID005289517
Drug	2,3-PDCA	GRIA1 GRIA3	5.33e-05	8	32	2	CID000127037
Drug	1-hydroxyimidazole	GRIA1 GRIA3	5.33e-05	8	32	2	CID003614351
Drug	homoibotenic acid	GRIA1 GRIA3	5.33e-05	8	32	2	CID000194385
Drug	1-hydroxypyrazole	GRIA1 GRIA3	5.33e-05	8	32	2	CID003016733
Drug	Ly294486	GRIA1 GRIA3	6.85e-05	9	32	2	CID005311255
Drug	1m5b	GRIA1 GRIA3	6.85e-05	9	32	2	CID000447081
Drug	isothiazol-3-one	GRIA1 GRIA3	6.85e-05	9	32	2	CID000096917
Drug	benzoyl-S-CoA	OXCT2 ACSM2A ACSM2B	7.38e-05	58	32	3	CID000122174
Drug	3,5-dihydroxyphenylglycine	GRIA1 GRIA3 ATP2A2	8.17e-05	60	32	3	CID000108001
Drug	Benzoates	GRIA1 GRIA3	8.55e-05	10	32	2	ctd:D001565
Drug	J-ST	GRIA1 GRIA3	1.04e-04	11	32	2	CID005288655
Drug	0-ol	GRIA1 GRIA3	1.04e-04	11	32	2	CID000069892
Drug	sym 2206	GRIA1 GRIA3	1.04e-04	11	32	2	CID005039877
Drug	YM872	GRIA1 GRIA3	1.04e-04	11	32	2	CID000148200
Drug	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	SPIRE2 ANK3 MBD5 MYO7A KIF26B SLC4A11 SEMA3E	1.06e-04	807	32	7	ctd:C548651
Drug	C-X6	GRIA1 GRIA3	1.25e-04	12	32	2	CID005288002
Drug	Atpa	GRIA1 GRIA3	1.25e-04	12	32	2	CID000002252
Drug	1NaPP1	GRIA1 GRIA3	1.25e-04	12	32	2	CID000004877
Drug	daunorubicin HCl; Down 200; 1uM; MCF7; HT_HG-U133A	USP34 ZHX3 ANK3 SLC6A14	1.44e-04	191	32	4	7507_DN
Drug	Naspm	GRIA1 GRIA3	1.48e-04	13	32	2	CID000129695
Drug	salicyluric acid	ACSM2A ACSM2B	1.48e-04	13	32	2	CID000010253
Drug	Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A	BBIP1 USP34 ANK3 ATXN7L1	1.49e-04	193	32	4	7059_DN
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A	AP4E1 USP34 ZHX3 ATP2A2	1.52e-04	194	32	4	4178_DN
Drug	NSC3260	OXCT2 GRIA1 GRIA3 ATP2A2	1.55e-04	195	32	4	CID000220461
Drug	Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	GRIA3 DNAH3 TSC22D2 ANK3	1.59e-04	196	32	4	2991_DN
Drug	Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A	AP4E1 USP34 ZHX3 UTP20	1.62e-04	197	32	4	4135_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	USP34 ZHX3 DNAH3 TSC22D2	1.62e-04	197	32	4	3566_DN
Drug	PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A	DNAH3 TSC22D2 ATXN7L1 SEMA3E	1.68e-04	199	32	4	6379_DN
Drug	Felbinac [5728-52-9]; Up 200; 18.8uM; HL60; HT_HG-U133A	AP4E1 GRIA1 GRIA3 KIF26B	1.68e-04	199	32	4	3061_UP
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; PC3; HT_HG-U133A	USP34 TSC22D2 PTGFR ATXN7L1	1.71e-04	200	32	4	5043_DN
Drug	quinoxaline-2,3-dione	GRIA1 GRIA3	1.72e-04	14	32	2	CID011469229
Drug	thiokynurenic acid	GRIA1 GRIA3	1.99e-04	15	32	2	CID003035667
Drug	nonanol	GRIA1 GRIA3	1.99e-04	15	32	2	CID000008914
Drug	phenylacetylglutamine	ACSM2A ACSM2B	1.99e-04	15	32	2	CID000092258
Drug	LY233536	GRIA1 GRIA3	2.27e-04	16	32	2	CID000126239
Drug	decahydroisoquinoline	GRIA1 GRIA3	2.27e-04	16	32	2	CID000097812
Drug	xenon	GRIA1 GRIA3 ATP2A2	2.55e-04	88	32	3	CID000023991
Drug	PPNDS	GRIA1 GRIA3	2.57e-04	17	32	2	CID005961627
Drug	7-Cl-Thio-Kyna	GRIA1 GRIA3	2.57e-04	17	32	2	CID003035668
Drug	MNQX	GRIA1 GRIA3	2.89e-04	18	32	2	CID000130818
Drug	2-butenedioate	OXCT2 GRIA1 GRIA3 ATP2A2	3.12e-04	234	32	4	CID000000723
Drug	LY382884	GRIA1 GRIA3	3.22e-04	19	32	2	CID000656723
Drug	IDRA 21	GRIA1 GRIA3	3.58e-04	20	32	2	CID000003688
Drug	aminocarnitine	OXCT2 ATP2A2	3.58e-04	20	32	2	CID000121830
Drug	AC1L194J	ACSM2A ACSM2B	3.95e-04	21	32	2	CID000000387
Drug	AC1L1B62	GRIA1 GRIA3	3.95e-04	21	32	2	CID000001299
Drug	Fe-mo-s Cluster	GRIA1 GRIA3	4.34e-04	22	32	2	CID000445682
Drug	anisamide	GRIA1 GRIA3	4.34e-04	22	32	2	CID000075540
Drug	NS 102	GRIA1 GRIA3	4.34e-04	22	32	2	CID005282252
Drug	CX516	GRIA1 GRIA3	4.34e-04	22	32	2	CID000148184
Drug	oxfenicine	OXCT2 ATP2A2	4.75e-04	23	32	2	CID000036143
Drug	CGP 39653	GRIA1 GRIA3	5.18e-04	24	32	2	CID006437837
Drug	pD 8	GRIA1 GRIA3	5.18e-04	24	32	2	CID000656948
Drug	Ns102	GRIA1 GRIA3	5.63e-04	25	32	2	CID005311098
Drug	cyclizine	OXCT2 GRIA1 ATP2A2	5.74e-04	116	32	3	CID000006726
Disease	X-21319 measurement	ACSM2A ACSM2B	1.07e-06	2	31	2	EFO_0800807
Disease	X-11478 measurement	ACSM2A ACSM2B	3.20e-06	3	31	2	EFO_0021242
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	1.07e-05	5	31	2	EFO_0800378
Disease	Frigidity	GRIA1 GRIA3	1.60e-05	6	31	2	C0016722
Disease	Psychosexual Disorders	GRIA1 GRIA3	1.60e-05	6	31	2	C0033953
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	1.60e-05	6	31	2	EFO_0800106
Disease	Hypoactive Sexual Desire Disorder	GRIA1 GRIA3	1.60e-05	6	31	2	C0020594
Disease	Sexual Arousal Disorder	GRIA1 GRIA3	1.60e-05	6	31	2	C0036902
Disease	Orgasmic Disorder	GRIA1 GRIA3	1.60e-05	6	31	2	C0029261
Disease	X-17676 measurement	DNAH3 ACSM2B	2.98e-05	8	31	2	EFO_0800785
Disease	central nervous system disease (implicated_via_orthology)	GRIA1 GRIA3	1.27e-04	16	31	2	DOID:331 (implicated_via_orthology)
Disease	urinary uromodulin measurement	DNAH3 ACSM2A ACSM2B	1.40e-04	96	31	3	EFO_0005663
Disease	age-related hearing impairment	GRIA1 SPIRE2 SLC4A11 SLC6A14	3.55e-04	324	31	4	EFO_0005782
Disease	uric acid measurement	USP34 ZHX3 DNAH3 ATP2A2 ACSM2B	4.04e-04	610	31	5	EFO_0004761

Protein segments in the cluster

Peptide	Gene	Start	Entry
TGLTCMVSKTMKIKP	ACSM2A	366	Q08AH3
SSKACKITKMPGMNS	ATXN7L1	786	Q9ULK2
KKMSFRKMDPSCTIG	ATG4C	371	Q96DT6
TVSAPTTTLKMMKEC	AP4E1	66	Q9UPM8
AAACLLPMLSMKKKS	CRISP1	11	P54107
KKTKCMSALSMPMLA	IQCH	881	Q86VS3
PIKGCKISTVSKAMV	KIF26B	1356	Q2KJY2
MSLGISIMIKKPQKS	GRIA3	526	P42263
KITSKHVKMMLSGVC	PTGFR	146	P43088
CLKPSVMTSATKIMS	LRIT3	251	Q3SXY7
STKVPMTSGVKQKIM	ATP2A2	531	P16615
KVAVKTMKPGSMSVE	HCK	286	P08631
KLVMESICIMKGMKP	DNAH3	2796	Q8TD57
MTMVLCKPKLLPLKS	BBIP1	46	A8MTZ0
EETKPCVPVSMKKMS	ANK3	4316	Q12955
CQECKKTIMPGTRKM	FHL2	101	Q14192
PTLTTKSPVMKKPMC	MBD5	301	Q9P267
SKPFMSLGISIMIKK	GRIA1	506	P42261
TCKKMASMTIKSLLG	UTP20	2341	O75691
LVLAPPKMKSTKTAM	SLC4A11	236	Q8NBS3
MSKMPAKKKSCFQIT	TSC22D2	1	O75157
TPKIMEKCTMPLTGK	OXCT2	446	Q9BYC2
TGLTCMVSKTMKIKP	ACSM2B	366	Q68CK6
CTSCSIKMKMPSKKF	SPIRE2	596	Q8WWL2
PSTALKMEECIMKGK	SEMA3E	96	O15041
NMCLLPTMVETSKGK	USP34	3116	Q70CQ2
VGICSMAKKSKSKPM	PPIP5K2	46	O43314
KVMKKMRVPITLGCC	SLC6A14	441	Q9UN76
MASKRKSTTPCMIPV	ZHX3	1	Q9H4I2
IVGICAMTKKSKSKP	PPIP5K1	56	Q6PFW1
LIPKMKISPKRMSCS	TRIM59	301	Q8IWR1
ATKSKKPIMLPVTFM	MYO7A	1251	Q13402