Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoIncreased serum bile acid concentration

EFL1 UNC45A VPS33B CCDC47

2.34e-0523394HP:0012202
HumanPhenoAbnormal serum bile acid concentration

EFL1 UNC45A VPS33B CCDC47

3.89e-0526394HP:0030984
DomainDCN-prot

DCUN1D1 DCUN1D3

3.34e-0451092IPR014764
DomainPONY_dom

DCUN1D1 DCUN1D3

3.34e-0451092IPR005176
DomainDCUN1

DCUN1D1 DCUN1D3

3.34e-0451092PS51229
DomainCullin_binding

DCUN1D1 DCUN1D3

3.34e-0451092PF03556
Domainzf-C2H2_6

ZNF729 ZNF502 ZNF155 PEG3 ZNF208 ZNF850 ZNF551 ZNF578

5.10e-043141098PF13912
DomainZINC_FINGER_C2H2_2

ZNF729 ZNF502 ZNF704 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF702P ZNF551 ZNF74 ZNF578 PRDM15

5.81e-0477510913PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 ZNF502 ZNF704 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF702P ZNF551 ZNF74 ZNF578 PRDM15

5.95e-0477710913PS00028
Domainzf-C2H2

ZNF729 ZNF502 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF702P ZNF551 ZNF74 ZNF578 PRDM15

7.23e-0469310912PF00096
DomainZnf_C2H2

ZNF729 ZNF502 ZNF704 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF702P ZNF551 ZNF74 ZNF578 PRDM15

8.26e-0480510913IPR007087
DomainZnF_C2H2

ZNF729 ZNF502 ZNF704 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF702P ZNF551 ZNF74 ZNF578 PRDM15

8.54e-0480810913SM00355
Domain-

CPXM2 MYCBP2 BTBD9 EPHB1

8.77e-047310942.60.120.260
DomainBTB

SPOPL BTBD9 KLHL38 IBTK SPOP

1.03e-031311095PF00651
DomainKRAB

ZNF729 ZNF155 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578

1.19e-033581098PS50805
DomainKRAB

ZNF729 ZNF155 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578

1.19e-033581098PF01352
DomainKRAB

ZNF729 ZNF155 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578

1.44e-033691098SM00349
DomainKRAB

ZNF729 ZNF155 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578

1.47e-033701098IPR001909
DomainAnk_3

ANK3 ANKRD62

1.47e-03101092PF13606
Domain-

ZNF729 ZNF502 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578 PRDM15

2.05e-03679109113.30.160.60
DomainMATH

SPOPL SPOP

2.14e-03121092PS50144
DomainMATH/TRAF_dom

SPOPL SPOP

2.14e-03121092IPR002083
DomainMATH

SPOPL SPOP

2.14e-03121092SM00061
DomainMATH

SPOPL SPOP

2.14e-03121092PF00917
DomainGalactose-bd-like

CPXM2 MYCBP2 BTBD9 EPHB1

2.24e-03941094IPR008979
DomainZnf_C2H2-like

ZNF729 ZNF502 ZNF704 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578 PRDM15

2.34e-0379610912IPR015880
DomainZnf_C2H2/integrase_DNA-bd

ZNF729 ZNF502 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578 PRDM15

2.43e-0369410911IPR013087
DomainBTB

SPOPL BTBD9 KLHL38 IBTK SPOP

2.47e-031601095PS50097
Domain-

SPOPL SPOP

2.93e-031410922.60.210.10
DomainBTB

SPOPL BTBD9 KLHL38 IBTK SPOP

4.10e-031801095SM00225
DomainBTB/POZ_dom

SPOPL BTBD9 KLHL38 IBTK SPOP

4.60e-031851095IPR000210
DomainPI3_PI4_kinase

PI4K2B SMG1

4.86e-03181092PF00454
DomainPI3_4_KINASE_1

PI4K2B SMG1

4.86e-03181092PS00915
DomainPI3_4_KINASE_2

PI4K2B SMG1

4.86e-03181092PS00916
DomainPI3/4_kinase_cat_dom

PI4K2B SMG1

4.86e-03181092IPR000403
DomainPI3_4_KINASE_3

PI4K2B SMG1

4.86e-03181092PS50290
DomainSKP1/BTB/POZ

SPOPL BTBD9 KLHL38 IBTK SPOP

5.03e-031891095IPR011333
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF729 ZNF704 PLXNA3 ZSCAN12 GCM2 PEG3 ETS1 ZNF208 BTBD9 IBTK UBTF AATF DCUN1D3

2.62e-068081141320412781
Pubmed

The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.

CUL4B DCUN1D1 DCUN1D3

7.38e-0612114319617556
Pubmed

Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.

CUL4B DCUN1D1 DCUN1D3

9.58e-0613114323201271
Pubmed

Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a.

PER2 UBE3A

1.07e-052114235401134
Pubmed

Circular RNA HIPK3 facilitates ferroptosis in gestational diabetes mellitus by regulating glutathione peroxidase 4 DNA methylation.

GPX4 HIPK3

1.07e-052114237253602
Pubmed

Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4.

DRD1 GRK4

1.07e-052114212164861
Pubmed

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

SPOPL SPOP

1.07e-052114216740475
Pubmed

Evolutionary expansion of SPOP and associated TD/POZ gene family: impact of evolutionary route on gene expression pattern.

SPOPL SPOP

1.07e-052114220399258
Pubmed

Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4.

GPX4 SEPSECS

1.07e-052114234794077
Pubmed

Blood pressure and renal sodium handling in relation to genetic variation in the DRD1 promoter and GRK4.

DRD1 GRK4

1.07e-052114218413491
Pubmed

Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging.

SIRT1 PER2

1.07e-052114227346580
Pubmed

Association between GRK4 and DRD1 gene polymorphisms and hypertension: a meta-analysis.

DRD1 GRK4

1.07e-052114226730182
Pubmed

The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4.

DRD1 GRK4

1.07e-052114216338988
Pubmed

Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.

SPOPL SPOP

1.07e-052114216651542
Pubmed

HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.

ISL1 HIPK3 SPOP

1.22e-0514114326147758
Pubmed

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

CUL4B DCUN1D1 DCUN1D3

2.70e-0518114326906416
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH3 MCPH1 TOPAZ1 VPS13C RNASE12 RNF213 ICE1 RANBP3L ATAD2B ASNS PLCB3

3.16e-057361141129676528
Pubmed

Novel role of sorting nexin 5 in renal D(1) dopamine receptor trafficking and function: implications for hypertension.

DRD1 GRK4

3.19e-053114223195037
Pubmed

Expanding the PP2A Interactome by Defining a B56-Specific SLiM.

CDCA2 BUB1

3.19e-053114227998540
Pubmed

Computational and experimental insights into the circadian effects of SIRT1.

SIRT1 PER2

3.19e-053114230348778
Pubmed

Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.

USP34 GVINP1

3.19e-053114217203969
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

ANK3 MAP1B ETS1 ZFC3H1 UBTF CAMSAP2

4.14e-05191114620195357
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CUL4B USP34 MAP1B MYCBP2 DHX57 UBTF ATAD2B ASNS NCAPD2 AATF

6.01e-056531141022586326
Pubmed

NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging.

SIRT1 PER2

6.36e-054114232369735
Pubmed

GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.

GPX4 USP14

6.36e-054114238228715
Pubmed

Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.

NCAPH2 NCAPD2

6.36e-054114227737959
Pubmed

Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent α-synuclein-induced ferroptosis in Parkinson's disease.

GPX4 SIRT1

6.36e-054114238488331
Pubmed

Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis.

GPX4 SIRT1

6.36e-054114238617450
Pubmed

Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.

MAP1B DNAH8

6.36e-054114215762842
Pubmed

Involvement of Parkin in the ubiquitin proteasome system-mediated degradation of N-type voltage-gated Ca2+ channels.

MAP1B UBE3A

6.36e-054114228957379
Pubmed

Ube3a imprinting impairs circadian robustness in Angelman syndrome models.

PER2 UBE3A

6.36e-054114225660546
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 SMG1 ZSCAN12 VPS13C CECR2 ICE1 IBTK TRANK1 NCAPD2

6.42e-05529114914621295
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

USP34 CACNA1D ANK3 VPS13C PEG3

6.65e-05128114530995482
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

CUL4B USP34 EFL1 OXR1 BZW2 ACO1 UNC45A GMPR2 SIRT1 USP14 DCUN1D1 UBE3A ASNS NCAPD2 PLCB3

8.36e-0514551141522863883
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PLXNA3 SMG1 ZSCAN12 RNF213 GMPR2 HIPK3 PLA2R1 TRANK1 NEK11

8.88e-05552114910737800
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

MYH3 DNAH8 EPHB1

9.47e-0527114318649358
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

NCAPH2 ZFC3H1 SIRT1 UBTF AATF POLQ

9.50e-05222114637071664
Pubmed

Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.

SPOPL SPOP

1.06e-045114222632832
Pubmed

A dual role of EphB1/ephrin-B3 reverse signaling on migrating striatal and cortical neurons originating in the preoptic area: should I stay or go away?

ISL1 EPHB1

1.06e-045114225100946
Pubmed

SIRT1 regulates circadian clock gene expression through PER2 deacetylation.

SIRT1 PER2

1.06e-045114218662546
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

PLXNA3 GCM2 SPOPL PEG3 ETS1 ISL1 IBTK PER2 UBTF DCUN1D3

1.18e-047091141022988430
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CUL4B USP34 EFL1 RNF213 UNC45A PPWD1 SIRT1 USP14 UBE3A UBTF ASNS NCAPD2

1.28e-0410141141232416067
Pubmed

The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation.

CUL4B SPOP

1.58e-046114231296559
Pubmed

Murine phospholipid hydroperoxide glutathione peroxidase: cDNA sequence, tissue expression, and mapping.

GPX4 PLA2R1

1.58e-046114210341094
Pubmed

Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.

SIRT1 KLKB1

1.58e-046114225339356
Pubmed

Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.

ANK3 TRANK1

1.58e-046114222182935
Pubmed

Retinal dopamine mediates multiple dimensions of light-adapted vision.

DRD1 PER2

1.58e-046114222764243
Pubmed

α2-chimaerin is required for Eph receptor-class-specific spinal motor axon guidance and coordinate activation of antagonistic muscles.

ISL1 EPHB1

1.58e-046114225673830
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

CUL4B MAP1B RNF213 DHX57 AATF POLQ

1.81e-04250114633536335
Pubmed

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.

MCPH1 SIRT1

2.21e-047114229129787
Pubmed

Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.

ZNF155 ZNF223

2.21e-04711428617494
Pubmed

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

DCUN1D1 DCUN1D3

2.21e-047114215988528
Pubmed

Molecular markers near two mouse chromosome 13 genes, muted and pearl, which cause platelet storage pool deficiency (SPD).

DRD1 MAP1B

2.21e-04711427719021
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

CUL4B GRK4 MAP3K5 KLHL38 ZNF74 NEK11 EPHB1

2.34e-04372114722939624
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

CUL4B MAP1B GPX4 RNF213 BTBD9 USP14 DCUN1D1 DCUN1D3

2.35e-04495114828581483
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PI4K2B USP34 SMG1 PLOD3 MAP1B BZW2 RNF213 DHX57 UNC45A USP14 CCDC47 UBTF ASNS NCAPD2

2.68e-0414401141430833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PLXNA3 SMG1 MYH3 MAP1B DHX57 ZFC3H1 CDCA2 CCDC47 SLC22A14 NCAPD2 AATF POLQ CAMSAP2 DNAH8

2.71e-0414421141435575683
Pubmed

Genome-wide association study reveals two new risk loci for bipolar disorder.

ANK3 TRANK1

2.94e-048114224618891
Pubmed

SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).

DCUN1D1 DCUN1D3

2.94e-048114225349211
Pubmed

Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.

NCAPH2 NCAPD2

2.94e-048114225474630
Pubmed

Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons.

MYH3 ISL1

2.94e-048114214643678
Pubmed

Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.

NCAPH2 NCAPD2

2.94e-048114214532007
Pubmed

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.

PEG3 SIRT1

2.94e-048114212482959
Pubmed

Reconstitution and subunit geometry of human condensin complexes.

NCAPH2 NCAPD2

2.94e-048114217268547
Pubmed

Transcriptional profiling reveals the transcription factor networks regulating the survival of striatal neurons.

DRD1 ISL1

2.94e-048114233712552
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 MAP1B DHX57 ZNFX1 CEMIP IBTK BUB1 PLCB3 DDX11L8

2.99e-04650114938777146
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF155 ZNF223 ZNF702P

3.59e-0442114334673265
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF704 ANK3 MCPH1 MAP1B MYCBP2 SOBP VPS13C SLC22A23 FRMPD2 RNF213 BTBD9 HIPK3 USP14 PRDM15

3.75e-0414891141428611215
Pubmed

Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice.

DRD1 SI

3.78e-049114216525059
Pubmed

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.

PLOD3 VPS33B

3.78e-049114227435297
Pubmed

A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function.

GCM2 ISL1

4.71e-0410114222087235
Pubmed

Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling.

MAP1B ISL1

4.71e-0410114224656932
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF208

4.71e-0410114218588511
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 ISL1

4.71e-0410114218804103
Pubmed

Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.

CACNA1D KLHL38

4.71e-0410114225055868
Pubmed

Multiple tumor suppressor pathways negatively regulate telomerase.

MCPH1 SIRT1

4.71e-0410114212837246
Pubmed

The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development.

PLXNA3 ISL1

4.71e-0410114219020035
Pubmed

Condensins I and II are essential for construction of bivalent chromosomes in mouse oocytes.

NCAPH2 NCAPD2

4.71e-0410114221795393
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

BZW2 RNF213 UBTF NCAPD2 AATF

4.71e-04195114519454010
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MAP1B MYCBP2 DHX57 UNC45A CDCA2 USP14 VPS33B UBE3A CCDC47 UBTF ASNS NCAPD2 AATF

5.01e-0413531141329467282
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DHX57 ZNFX1 ICE1 UNC45A NCAPD2

5.53e-04202114533005030
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF729 ZNF208 ZNF850

5.66e-044911439630514
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF208

5.75e-0411114215469996
Pubmed

SRC family kinases are required for limb trajectory selection by spinal motor axons.

ISL1 EPHB1

5.75e-0411114219403835
Pubmed

Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors.

CECR2 NCAPD2

5.75e-0411114220589882
Pubmed

Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.

GCM2 ISL1

5.75e-0411114220215350
Pubmed

TIP120A associates with cullins and modulates ubiquitin ligase activity.

CUL4B UBE3A

5.75e-0411114212609982
Pubmed

Foxd1 is required for proper formation of the optic chiasm.

ISL1 EPHB1

5.75e-0411114215509772
Pubmed

An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles.

MYH3 ISL1

5.75e-0411114211988168
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 USP34 PLOD3 MAP1B MYCBP2 ERAP1 BZW2 RNF213 NCAPH2 PLA2R1 CCDC47 RFT1

5.91e-0412011141235696571
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

MYCBP2 TOPAZ1 RNF213 TRANK1

5.91e-04116114421282530
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 PLOD3 MYCBP2 ZFC3H1 CDCA2 UBTF AATF

6.37e-04440114734244565
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

OXR1 ISL1 HIPK3 PLA2R1 ANGEL2 AATF

6.50e-04318114616919269
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

EFL1 PLOD3 ANK3 MYCBP2 BZW2 RNF213 CDCA2 VPS33B CCDC47 UBTF AATF

6.79e-0410491141127880917
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

CUL4B ACO1 UNC45A UBE3A ASNS

6.88e-04212114533462405
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

USP34 MYCBP2 NCAPH2 ZFC3H1 UBE3A

6.88e-04212114533853758
Pubmed

SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

CUL4B DCUN1D1

6.88e-0412114218826954
Pubmed

Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.

SPOPL SPOP

6.88e-0412114228412462
Pubmed

Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice.

ISL1 SIRT1

6.88e-0412114228436940
Pubmed

Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes.

PER2 UBE3A

6.88e-0412114217901046
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF729 ZNF502 ZSCAN12 ZNF155 PEG3 ZNF208 ZNF223 ZNF850 ZNF551 ZNF74 ZNF578 PRDM15

6.91e-06718641228
GeneFamilyBasic leucine zipper proteins|BTB domain containing

SPOPL BTBD9 KLHL38 IBTK SPOP

1.11e-04134645861
GeneFamilyAnkyrin repeat domain containing

ANK3 ANKRD62 IBTK TRANK1 ANKRD13C

1.65e-03242645403
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP

EFL1 MCPH1 OXR1 ACO1 CDCA2 NCAPD2 PRDM15

1.47e-051811147M6857
CoexpressionGSE15659_TREG_VS_TCONV_DN

PLXNA3 ZNF155 ANK3 PEG3 ISL1 DCUN1D1 TC2N

1.88e-051881147M3535
CoexpressionGSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP

SMG1 BZW2 ICE1 MAP3K5 ANGEL2 AATF PRDM15

2.80e-052001147M6447
CoexpressionGSE27786_BCELL_VS_MONO_MAC_UP

USP34 SMG1 MYCBP2 UBE3A UBTF ATAD2B CAMSAP2

2.80e-052001147M4817
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

USP34 SMG1 ZNF155 OXR1 SPOPL DCUN1D1 TRANK1

5.22e-07186114703db813598b67b1e08f759758a1c2023396921fa
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 ANK3 ETS1 RNF213 ZFC3H1 TC2N

7.68e-07197114757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 ANK3 RNF213 ZFC3H1 TC2N ATAD2B

8.22e-071991147f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 MYCBP2 VPS13C RNF213 ZFC3H1 ATAD2B

8.50e-07200114712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellmild_COVID-19_(asymptomatic)-RBC|World / disease group, cell group and cell class (v2)

PI4K2B ABHD18 ANKRD62 FANCB ZNF74 SPOP

4.90e-0616911462bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRP1 CDCA2 FANCB BUB1 NCAPD2 POLQ

5.99e-061751146876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PI4K2B ANK3 SOBP RNF213 ZNFX1 TRANK1

6.81e-061791146af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 ESRP1 CDCA2 BUB1 NCAPD2 POLQ

7.49e-061821146336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYCBP2 RNF213 ZNF223 TRANK1 TC2N DCUN1D3

1.11e-05195114683c125223e7ca0f08a31414b3a16347912564765
ToppCellTransverse-T_cell-cycling_gd_T|Transverse / Region, Cell class and subclass

MORC1 ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.21e-0519811465131b0b7d6c4dd8872cef9f2e233f59f751b4690
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_Tem|Bac-SEP / Disease, condition lineage and cell class

PLXNA3 ETS1 ZNF208 TC2N ZNF74 NEK11

1.21e-051981146292b26f316f016b50d07689f84772eec46060251
ToppCellTransverse-(1)_T_cell-(18)_cycling_gd_T|Transverse / shred on region, Cell_type, and subtype

MORC1 ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.21e-051981146396dddf7ebad41c3a91329b6a280623c0dfdcd2f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D ANK3 OXR1 MAP1B PEG3 UBE3A

1.21e-0519811460ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MAP1B ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.25e-051991146be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1D ANK3 OXR1 MAP1B MYCBP2 UBE3A

1.28e-05200114648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

PI4K2B ZNF850 SEPSECS NCAPD2 POLQ

2.64e-051361145d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYOM1 MAP1B NOXA1 HIPK3 NEK11

4.64e-05153114544572f87d403e314050ab935d2cd676c33d9c287
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_TEM|Bac-SEP / Disease, Lineage and Cell Type

PLXNA3 ETS1 ZNF208 TC2N NEK11

5.09e-051561145ef6bad99bcb30956863cd490c613e251f3b27ba0
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYOM1 MAP1B NOXA1 HIPK3 NEK11

5.25e-051571145a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellMild-Lymphoid-NK-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

PI4K2B ANK3 GRK4 ZNF208 TC2N

6.09e-051621145bd218e41b2eadc3bba4c7ac3e34a014f6ad8b1bf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 CDCA2 BUB1 NCAPD2 POLQ

6.64e-051651145eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tfh|bone_marrow / Manually curated celltypes from each tissue

ZNF502 ANK3 MAP3K5 TC2N ANGEL2

6.83e-0516611459ac5267d3a53a96dec9eae3bc01acba4750742c8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 SCGB2A1 BUB1 NCAPD2 POLQ

7.03e-05167114550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PLOD3 ISL1 PLA2R1 TC2N KCNH5

7.03e-051671145e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

ZNF208 CDCA2 FANCB RANBP3L NCAPD2

7.43e-051691145eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 MAP1B SLC22A23 TC2N EPHB1

7.64e-0517011456035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIRT1 CDCA2 BUB1 NCAPD2 POLQ

7.64e-0517011452d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 MAP1B SLC22A23 TC2N EPHB1

7.64e-051701145c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 MAP1B SLC22A23 TC2N EPHB1

7.64e-051701145dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellmild_COVID-19_(asymptomatic)-RBC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ABHD18 ANKRD62 FANCB NCAPD2 ZNF74

7.86e-05171114578491478ba65bad45238fe114f5251b2adea323d
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

MORC1 CDCA2 BUB1 NCAPD2 POLQ

8.08e-0517211458d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH3 MCPH1 CDCA2 NCAPD2 DNAH8

9.24e-0517711458a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH3 MCPH1 CDCA2 NCAPD2 DNAH8

9.24e-051771145e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PI4K2B ESRP1 CDCA2 BUB1 NCAPD2

9.24e-051771145a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

IL1RL2 MAP3K5 CEMIP ANGEL2 PRDM15

9.24e-051771145eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 FANCB BUB1 NCAPD2 POLQ

9.49e-0517811451893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMG1 ZNF155 NCAPD2 POLQ TRMT12

9.49e-051781145c87945146b2734141f07b39d268e0d8086ee0364
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PI4K2B ANK3 ESRP1 TC2N KLKB1

9.75e-051791145bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 ETS1 ISL1 PLA2R1 GVINP1

1.00e-041801145dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.00e-041801145401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 ETS1 ISL1 PLA2R1 GVINP1

1.00e-041801145423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCM2 ESRP1 CDCA2 BUB1 NCAPD2

1.00e-04180114543fd5c498a87bb078d101298b472656f3294686a
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 SMG1 ANK3 RNF213 TC2N

1.03e-041811145f2315414e714ac86211546a935660c4be6e85f1b
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

ZNF704 CDCA2 FANCB BUB1 POLQ

1.05e-0418211459adf90bb2808f234d53b89ca0ae07380478204ad
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETS1 CDCA2 BUB1 NCAPD2 DNAH8

1.05e-041821145bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PI4K2B SOBP ZNFX1 TRANK1 DNAH8

1.08e-041831145dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GCM2 ESRP1 CDCA2 BUB1 NCAPD2

1.08e-041831145e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ZNF704 CDCA2 FANCB BUB1 POLQ

1.08e-041831145df8568751205313d149939ea2683097e3652a60b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC22A23 CECR2 NOXA1 ESRP1 TC2N

1.11e-0418411457cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 SLC22A23 CECR2 ESRP1 TC2N

1.11e-041841145ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TC2N BUB1 NCAPD2 POLQ KLKB1

1.11e-04184114516aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 BZW2 CECR2 ESRP1 TC2N

1.14e-041851145fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 CECR2 ESRP1 BTBD9 TC2N

1.17e-0418611452ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.17e-0418611450067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 BZW2 CECR2 ESRP1 TC2N

1.17e-041861145e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 SLC22A23 CECR2 ESRP1 TC2N

1.20e-041871145201ff693e4756ee3e44762885b3a303a77eb535b
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D MAP1B PEG3 ISL1 ASNS

1.20e-0418711455f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.20e-0418711459351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 CDCA2 BUB1 NCAPD2 POLQ

1.20e-041871145057569c9437219ecc396aa6e673b1178a2273837
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 SMG1 VPS13C RNF213 BTBD9

1.23e-041881145ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PI4K2B ANK3 RNF213 ZNFX1 TRANK1

1.23e-0418811456f8946d4710f6e32c937213f99b790b098b8819c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 SLC22A23 CECR2 ESRP1 TC2N

1.23e-04188114543a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 SLC22A23 CECR2 ESRP1 TC2N

1.23e-0418811454bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

USP34 MAP1B MYCBP2 PEG3 TRANK1

1.23e-041881145b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ANK3 MYCBP2 SLC22A23 CECR2 ASNS

1.26e-0418911453717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 CECR2 ESRP1 BTBD9 TC2N

1.29e-0419011458aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ESRP1 CDCA2 TC2N BUB1 POLQ

1.32e-04191114539220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1D SLC22A23 CEMIP PLA2R1 EPHB1

1.32e-041911145fa380a8752de158974b2ae5e741573439719cc0d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.35e-0419211450a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 ANK3 RNF213 BTBD9 TC2N

1.35e-04192114547646d7e4990be85072987f92bf18d52f8da752e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.35e-041921145026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 ANK3 RNF213 TC2N ATAD2B

1.39e-0419311459337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.39e-041931145cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D ANK3 MAP1B PEG3 TRANK1

1.39e-0419311451aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ESRP1 CDCA2 TC2N BUB1 POLQ

1.42e-041941145c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.42e-041941145f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PI4K2B SOBP RNF213 ZNFX1 TRANK1

1.45e-041951145b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.45e-041951145926eb3fc5d028be936885bea0654a77db3107234
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D MAP1B MYCBP2 VPS13C PEG3

1.45e-0419511453e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.45e-0419511451a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D MAP1B MYCBP2 VPS13C PEG3

1.45e-0419511457796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.49e-0419611451d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.49e-0419611451964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.49e-04196114573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

ZNF704 MAP1B SLC22A23 ASNS EPHB1

1.49e-0419611459401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellprimary_visual_cortex-Neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANK3 OXR1 MAP1B USP14 ASNS

1.49e-0419611458efc2b3a95f57c31be203ac781b2098d4909297f
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANK3 OXR1 MAP1B USP14 ASNS

1.49e-041961145de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK3 ETS1 ICE1 TC2N GVINP1

1.49e-0419611454a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.53e-04197114584ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLXNA3 SMG1 ANK3 RNF213 TC2N

1.53e-041971145e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.53e-0419711458b616cde333bdbc0c591035ad9e4949155866245
ToppCellCaecum-B_cell-B_cell_cycling|Caecum / Region, Cell class and subclass

ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.56e-04198114561294fe99a5641ad359796022c3d038470076b3c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D OXR1 MAP1B PEG3 UBE3A

1.56e-0419811456d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg|ICU-NoSEP / Disease, condition lineage and cell class

CUL4B CACNA1D ETS1 ZNF208 ZNF850

1.56e-0419811451ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D OXR1 MAP1B PEG3 UBE3A

1.56e-0419811454ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.56e-0419811456981cd5b1585c8ae6febdf0c4fb83067127f106c
ToppCellCaecum-(2)_B_cell-(24)_B_cell_cycling|Caecum / shred on region, Cell_type, and subtype

ZNF850 CDCA2 BUB1 NCAPD2 POLQ

1.56e-041981145568d47770cd20c6569ca84ea1eafde367642d68b
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 FANCB BUB1 NCAPD2 POLQ

1.56e-041981145281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCellTransverse-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

MORC1 ZNF850 CDCA2 BUB1 POLQ

1.60e-0419911457cfe9b2538ea008d67343f3e8bfec3bf81200de6
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

ANK3 SOBP RNF213 ZNFX1 TRANK1

1.60e-041991145056a0538ca5e825ae6195b4c76c208708a014533
DiseaseManic

CACNA1D DRD1 ANK3 TRANK1 DNAH8

1.17e-05781115C0338831
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

MCPH1 BUB1 NCAPD2

2.80e-05161113DOID:0070296 (is_implicated_in)
DiseaseManic Disorder

CACNA1D DRD1 ANK3 TRANK1

1.52e-04711114C0024713
DiseaseDepression, Bipolar

CACNA1D DRD1 ANK3 TRANK1

2.29e-04791114C0005587
Diseasegranulocyte colony-stimulating factor measurement

MAP1B SEPSECS ANKRD13C

2.85e-04341113EFO_0008142
Diseasehemolysis

GPX4 UBTF ATAD2B

7.45e-04471113EFO_0009473
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

MYCBP2 KLKB1

7.54e-04111112EFO_0801871
Diseasehypertension

CACNA1D ERAP1 RNF213 VPS33B RANBP3L PLCB3

1.10e-033071116EFO_0000537
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

PRDM15 KLKB1

1.84e-03171112EFO_0008011
DiseaseBipolar Disorder

CACNA1D DRD1 ANK3 SIRT1 TRANK1 PER2 DNAH8

2.21e-034771117C0005586
DiseaseArthrogryposis

MYH3 VPS33B

2.81e-03211112C0003886
DiseaseParkinson's disease (implicated_via_orthology)

DRD1 VPS13C SIRT1 HIPK3

2.97e-031571114DOID:14330 (implicated_via_orthology)
Diseasenicotine dependence

SLC22A23 ICE1 CAMSAP2

3.21e-03781113EFO_0003768
DiseaseHuntington's disease (is_implicated_in)

SIRT1 MAP3K5

3.37e-03231112DOID:12858 (is_implicated_in)
Diseaseleptin measurement

DRD1 DCUN1D1 DNAH8

3.57e-03811113EFO_0005000
Diseasecarnosine measurement

OXR1 KLKB1

3.67e-03241112EFO_0010470

Protein segments in the cluster

PeptideGeneStartEntry
MEISCTSQGFFFLKE

nan

1

Q6ZS49
AVSDMKKDFESCLGA

ACO1

381

P21399
FKAMTEDGFLAVCSE

ASNS

146

P08243
DDGDKTKMTNHCVFS

BZW2

86

Q9Y6E2
DDSKMKNFITCFKDP

C8orf82

56

Q6P1X6
SMFAVASKDAGCVNK

BUB1

396

O43683
ETQALKAAFMKCGSE

EFL1

391

Q7Z2Z2
CSDNGGEKMKTFFEK

GVINP1

2166

Q7Z2Y8
FTTTDSFKMGQEFVK

ABHD18

231

Q0P651
DFTDMKCQRGDLSFI

ANKRD13C

266

Q8N6S4
EQSGMECKDFVSLSK

ANKRD62

406

A6NC57
VECSQPESSFKMSFK

DRD1

251

P21728
PKCEDSENKFDFSVM

ANGEL2

156

Q5VTE6
NEREKFAFCSMKGCE

CEMIP

1146

Q8WUJ3
GLYCTKEEFVNDMKT

CECR2

491

Q9BXF3
AATQCEFSKQEFMDG

DCUN1D1

111

Q96GG9
AATMCKFTRKEFFDG

DCUN1D3

136

Q8IWE4
AKAEGFTASTKNCMV

CPXM2

691

Q8N436
VNYKFESGTCSKMEL

ESRP1

206

Q6NXG1
FDQAVTKDTCMAVGF

NOXA1

61

Q86UR1
GVTECFTFAAMSKEE

RFT1

386

Q96AA3
LFTKKEETMTCVFFS

MORC1

116

Q86VD1
DTDPDMAFCKSFRDK

PLOD3

486

O60568
KFSGKMCFQTLTDDD

EPHB1

516

P54762
DVSQFGSFKEDTKMS

MAP1B

1506

P46821
FEMSDFSCVGKKTRT

MCPH1

456

Q8NEM0
FLCDVTMKSVDGKEF

IBTK

766

Q9P2D0
NECSQGDKKVAFFMR

ATAD2B

456

Q9ULI0
KSSTCSFMYGELTDK

KCNH5

61

Q8NCM2
MQDLSEFCSDKPKSG

CCDC47

276

Q96A33
FGKCFDAMEVDALNS

ERAP1

401

Q9NZ08
NEFSLKGVDFQKFCM

ETS1

86

P14921
GADSFTQECMEEKSF

PER2

256

O15055
KFFTSKIVRMCAGDS

PLXNA3

256

P51805
NMDDYTFESAKKVCG

DNAH8

3251

Q96JB1
MLKFQEAAKCVSGST

NEK11

1

Q8NG66
ADLCTKGVQTMEDFK

LCA5

326

Q86VQ0
DTVGTFEMAKVLCKF

GMPR2

56

Q9P2T1
GTKSTRFFCKETDMS

HIPK3

426

Q9H422
KEKLCDFTDGRDAFM

PEG3

681

Q9GZU2
ESNFMQRCEVSKGKS

FANCB

781

Q8NB91
DKGFDKATFESQMSV

PI4K2B

406

Q8TCG2
RDFCHSKKMTGSNTE

OXR1

296

Q8N573
RNKCFEMSSFVETKA

PLCB3

611

Q01970
SVTADGCKDIFMKNE

IL1RL2

16

Q9HB29
ELMQKFSCLGTTDKD

ILRUN

11

Q9H6K1
SVFMKATKDGQCESQ

ICE1

741

Q9Y2F5
FSFVQMEKESCSHLK

FRMPD2

1091

Q68DX3
CFSETFGERMKISEA

DHX57

221

Q6P158
FMTETVKNCKRDGFV

POLQ

2426

O75417
CEKSMISRKLFGFTE

DDX11L8

501

A8MPP1
SEKELCKMADSFFGT

ANK3

2091

Q12955
CKMADSFFGTDTILE

ANK3

2096

Q12955
KENEKMTGCLEFSEA

CDCA2

156

Q69YH5
SSINDMEKRFGCFLK

KLKB1

66

P03952
KNFYIESKATSCMSE

DDX53

176

Q86TM3
SEQLKDMVAFFLGCS

DGLUCY

111

Q7Z3D6
KFDMFSKICVNGDDA

GPX4

126

P36969
MIESGCFKDINKSES

GRK4

516

P32298
ECMFTNKTFTLEKGL

BTBD9

406

Q96Q07
NEFDLVCGMETKKDT

SLC22A14

171

Q9Y267
LSAIFCFQSETKFKM

RNASE12

91

Q5GAN4
KMHKTCFFADSDIVA

CACNA1D

296

Q01668
CGFFFKDDQKAENDM

CAMSAP2

1161

Q08AD1
ECGAAFTSKLEGMFK

CUL4B

636

Q13620
VDRKKNMFCSTSGTE

LGSN

321

Q5TDP6
SMSAEAKAFILKCFE

MAP3K5

906

Q99683
QEMDEKFKECLAGTS

SULT6B1

276

Q6IMI4
FKSSAKEGSNAIEFM

TC2N

276

Q8N9U0
SGMSDSVKDKFSIAF

SLC22A23

526

A1A5C7
KDFMCELCGKTFSER

PRDM15

1166

P57071
YKATCDLATFQGDKM

GCM2

241

O75603
ALFCSVGDDKAMKVF

PPWD1

146

Q96BP3
SCFSEDQMAKPIKAF

SMG1

3071

Q96Q15
KSNDDLDVSESKGCM

SIRT1

561

Q96EB6
EEECMFPKATDTSFK

MYH3

536

P11055
EKCEDGKTETTFEMS

MYCBP2

3131

O75592
FMCIEDTSGKSFGVF

SI

281

P14410
KCSIGFSKNDFVMRA

ISL1

81

P61371
MSFEAAHEFCKKEGS

PLA2R1

1271

Q13018
VQSISDFEKFTKGMD

AATF

151

Q9NY61
RKMLDNFDCFGDKLS

NCAPD2

1241

Q15021
CISFDEGKTTMNFIE

NCAPH2

41

Q6IBW4
ASQGFMRKTEDECSF

RNF213

2621

Q63HN8
MREKSFQCNETGEAF

ZNF578

226

Q96N58
GKCKQSFSDMSIFDL

ZNF223

151

Q9UK11
MREKSFQCNESGKAF

ZNF702P

1

Q9H963
FFKVETENKFSFMTC

UBE3A

466

Q05086
MGSEVKSFCSEKCFA

SOBP

166

A7XYQ1
DSDAAAEAMGKFKQC

SCGB2A1

51

O75556
FSFCREEMGEVLKSS

SPOPL

41

Q6IQ16
FSFCREEMGEVIKSS

SPOP

41

O43791
KSCSSNFVFGENMVE

RANBP3L

206

Q86VV4
QKMFECSECEESFSK

ZNF551

276

Q7Z340
KISMQCFDFTDSKGE

VPS13C

1476

Q709C8
GSLVCMSKDNFETFL

ZNFX1

451

Q9P2E3
MTFTFQSEDLKRDCG

ZNF704

1

Q6ZNC4
KSKDSRNADFMVGEC

TOPAZ1

1006

Q8N9V7
VKMGCEKFADFQTFC

TOPAZ1

1306

Q8N9V7
EECGKGFSMFSILTK

ZNF208

456

O43345
QDSTFEEKYACEGMK

ZNF502

51

Q8TBZ5
EKLFMCDVCGKEFSQ

ZNF155

201

Q12901
SGEKSFKCEKCGEMF

ZNF74

551

Q16587
DQKSCFKSMITAGFE

SEPSECS

171

Q9HD40
DVTQCMFSFGNITEK

TRMT12

211

Q53H54
GLEKEQEFISKCMES

USP34

1131

Q70CQ2
AEKEMVKSCFEFFGI

TRANK1

2061

O15050
EKVAFKDFSGDMCKL

UBTF

56

P17480
FFGVEFETTMKCTES

USP14

246

P54578
SKFENDMSKSARCGE

ZSCAN12

211

O43309
FSKRGTKDEVQEMCE

ZFC3H1

1411

O60293
TDFSMKQFAEGSTLK

UNC45A

511

Q9H3U1
CSDFAFTDMTKEDKA

VPS33B

546

Q9H267
KSTECMAFKYGSELT

ZNF850

171

A8MQ14
EECVKAFNSFSALMK

ZNF729

771

A6NN14
AMFCSSFREKSEAKV

KLHL38

61

Q2WGJ6
LNFECDKMTPKSEFS

MYOM1

1156

P52179