Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.22e-10	279	75	12	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D OBSCN HERC2 TBC1D3I TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	5.38e-10	507	75	15	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D OBSCN HERC2 TBC1D3I TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	5.38e-10	507	75	15	GO:0030695
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D OBSCN ATG14 NCK1 APOBEC1 HERC2 TBC1D3I LYN TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	8.22e-07	1418	75	19	GO:0030234
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D APOBEC1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	8.97e-07	656	75	13	GO:0008047
GeneOntologyMolecularFunction	sulfate adenylyltransferase (ATP) activity	PAPSS2 PAPSS1	1.39e-05	2	75	2	GO:0004781
GeneOntologyMolecularFunction	sulfate adenylyltransferase activity	PAPSS2 PAPSS1	1.39e-05	2	75	2	GO:0004779
GeneOntologyMolecularFunction	adenylylsulfate kinase activity	PAPSS2 PAPSS1	1.39e-05	2	75	2	GO:0004020
GeneOntologyMolecularFunction	recombination hotspot binding	PRDM9 PRDM7	1.39e-05	2	75	2	GO:0010844
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D APOBEC1 GPNMB TBC1D3I AHSA1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	4.54e-05	1233	75	15	GO:0140677
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	8.31e-05	4	75	2	GO:0005219
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity, type I	BMPR1A BMPR1B	1.38e-04	5	75	2	GO:0005025
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	2.07e-04	6	75	2	GO:0048763
GeneOntologyMolecularFunction	BMP receptor activity	BMPR1A BMPR1B	3.84e-04	8	75	2	GO:0098821
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	PRDM9 PRDM7	1.06e-03	13	75	2	GO:0046975
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity	BMPR1A BMPR1B	1.06e-03	13	75	2	GO:0005024
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulator activity	ATG14 LYN	2.05e-03	18	75	2	GO:0035014
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR2	2.05e-03	18	75	2	GO:0015278
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase activity	BMPR1A BMPR1B	2.53e-03	20	75	2	GO:0004675
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	PRDM9 PRDM7	2.53e-03	20	75	2	GO:0042800
GeneOntologyMolecularFunction	BMP binding	BMPR1A BMPR1B	3.06e-03	22	75	2	GO:0036122
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	KLHDC2 AMBRA1 FBXW11	3.64e-03	82	75	3	GO:1990756
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.98e-13	109	75	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	2.14e-13	244	75	14	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	1.56e-11	335	75	14	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I LYN TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	2.78e-10	499	75	15	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I LYN TBC1D3G TBC1D3C TBC1D3B HNRNPD RIC1 TBC1D3K WDR24 TBC1D3F	1.22e-07	1028	75	17	GO:0043085
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I LYN TBC1D3G TBC1D3C TBC1D3B RIC1 TBC1D3K TBC1D3F	5.07e-07	878	75	15	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of molecular function	TBC1D3E RAB3GAP1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D SNX18 TBC1D3I LYN AHSA1 TBC1D3G TBC1D3C TBC1D3B HNRNPD RIC1 RYR2 TBC1D3K WDR24 TBC1D3F	5.72e-07	1430	75	19	GO:0044093
GeneOntologyBiologicalProcess	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	PAPSS2 PAPSS1	1.30e-05	2	75	2	GO:0050428
GeneOntologyBiologicalProcess	purine ribonucleoside bisphosphate biosynthetic process	PAPSS2 PAPSS1	1.30e-05	2	75	2	GO:0034036
GeneOntologyBiologicalProcess	positive regulation of macroautophagy	RAB3GAP1 SNX18 ELAPOR1 AMBRA1 WDR24	2.13e-05	92	75	5	GO:0016239
GeneOntologyBiologicalProcess	positive regulation of autophagosome assembly	RAB3GAP1 SNX18 ELAPOR1	5.04e-05	20	75	3	GO:2000786
GeneOntologyBiologicalProcess	regulation of macroautophagy	RAB3GAP1 SNX18 ELAPOR1 AMBRA1 ATG14 WDR24	5.96e-05	186	75	6	GO:0016241
GeneOntologyBiologicalProcess	positive regulation of reciprocal meiotic recombination	PRDM9 PRDM7	7.79e-05	4	75	2	GO:0010845
GeneOntologyBiologicalProcess	sulfate assimilation	PAPSS2 PAPSS1	7.79e-05	4	75	2	GO:0000103
GeneOntologyBiologicalProcess	regulation of reciprocal meiotic recombination	PRDM9 PRDM7	7.79e-05	4	75	2	GO:0010520
GeneOntologyBiologicalProcess	autophagosome assembly	RAB3GAP1 SNX18 ELAPOR1 AMBRA1 ATG14	7.95e-05	121	75	5	GO:0000045
GeneOntologyBiologicalProcess	positive regulation of vacuole organization	RAB3GAP1 SNX18 ELAPOR1	1.00e-04	25	75	3	GO:0044090
GeneOntologyBiologicalProcess	autophagosome organization	RAB3GAP1 SNX18 ELAPOR1 AMBRA1 ATG14	1.08e-04	129	75	5	GO:1905037
GeneOntologyBiologicalProcess	positive regulation of autophagy	RAB3GAP1 SNX18 ELAPOR1 AMBRA1 WDR24	4.21e-04	173	75	5	GO:0010508
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.19e-15	49	73	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.48e-15	53	73	10	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.11e-14	55	73	10	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.11e-14	55	73	10	IPR000195
Domain	APS_kinase	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR002891
Domain	Sulphate_adenylyltransferase	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR002650
Domain	ATP-Sase_PUA-like_dom	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR025980
Domain	Sulfurylase_cat_dom	PAPSS2 PAPSS1	1.51e-05	2	73	2	IPR024951
Domain	ATP-sulfurylase	PAPSS2 PAPSS1	1.51e-05	2	73	2	PF01747
Domain	PUA_2	PAPSS2 PAPSS1	1.51e-05	2	73	2	PF14306
Domain	Ryanrecept_TM4-6	RYR1 RYR2	4.51e-05	3	73	2	IPR009460
Domain	RyR	RYR1 RYR2	4.51e-05	3	73	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR2	4.51e-05	3	73	2	IPR003032
Domain	RR_TM4-6	RYR1 RYR2	4.51e-05	3	73	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	4.51e-05	3	73	2	IPR013333
Domain	RIH_assoc	RYR1 RYR2	2.24e-04	6	73	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR2	2.24e-04	6	73	2	IPR013662
Domain	RIH_dom	RYR1 RYR2	2.24e-04	6	73	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	2.24e-04	6	73	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	2.24e-04	6	73	2	IPR015925
Domain	-	RYR1 RYR2	2.24e-04	6	73	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	2.24e-04	6	73	2	PF01365
Domain	Ins145_P3_rec	RYR1 RYR2	2.24e-04	6	73	2	PF08709
Domain	GS	BMPR1A BMPR1B	3.12e-04	7	73	2	SM00467
Domain	GS_dom	BMPR1A BMPR1B	3.12e-04	7	73	2	IPR003605
Domain	GS	BMPR1A BMPR1B	3.12e-04	7	73	2	PS51256
Domain	TGF_beta_GS	BMPR1A BMPR1B	3.12e-04	7	73	2	PF08515
Domain	EF-hand_8	CAPN2 RYR1 RYR2	3.14e-04	34	73	3	PF13833
Domain	SSXRD	PRDM9 PRDM7	4.16e-04	8	73	2	PF09514
Domain	SSXRD_motif	PRDM9 PRDM7	4.16e-04	8	73	2	IPR019041
Domain	Rossmann-like_a/b/a_fold	PAPSS2 PAPSS1 CRY1	6.32e-04	43	73	3	IPR014729
Domain	-	PAPSS2 PAPSS1 CRY1	6.32e-04	43	73	3	3.40.50.620
Domain	MIR	RYR1 RYR2	6.64e-04	10	73	2	PS50919
Domain	MIR	RYR1 RYR2	6.64e-04	10	73	2	PF02815
Domain	MIR	RYR1 RYR2	6.64e-04	10	73	2	SM00472
Domain	Activin_recp	BMPR1A BMPR1B	6.64e-04	10	73	2	IPR000472
Domain	MIR_motif	RYR1 RYR2	6.64e-04	10	73	2	IPR016093
Domain	Activin_recp	BMPR1A BMPR1B	6.64e-04	10	73	2	PF01064
Domain	KRAB_RELATED	PRDM9 PRDM7	8.10e-04	11	73	2	PS50806
Domain	TGFB_receptor	BMPR1A BMPR1B	9.70e-04	12	73	2	IPR000333
Domain	Krueppel-associated_box-rel	PRDM9 PRDM7	1.14e-03	13	73	2	IPR003655
Domain	SH3	SNX18 OBSCN NCK1 LYN YES1	1.57e-03	216	73	5	SM00326
Domain	SH3	SNX18 OBSCN NCK1 LYN YES1	1.57e-03	216	73	5	PS50002
Domain	Pkinase_Tyr	BMPR1A BMPR1B LYN YES1	1.64e-03	129	73	4	PF07714
Domain	SH3_domain	SNX18 OBSCN NCK1 LYN YES1	1.70e-03	220	73	5	IPR001452
Domain	Ser-Thr/Tyr_kinase_cat_dom	BMPR1A BMPR1B LYN YES1	2.09e-03	138	73	4	IPR001245
Domain	PUA-like_domain	PAPSS2 PAPSS1	2.47e-03	19	73	2	IPR015947
Domain	SH3_1	SNX18 NCK1 LYN YES1	3.90e-03	164	73	4	PF00018
Domain	WD_REPEATS_1	AMBRA1 HERC2 RIC1 WDR24 FBXW11	4.64e-03	278	73	5	PS00678
Domain	WD_REPEATS_2	AMBRA1 HERC2 RIC1 WDR24 FBXW11	4.71e-03	279	73	5	PS50082
Domain	WD_REPEATS_REGION	AMBRA1 HERC2 RIC1 WDR24 FBXW11	4.71e-03	279	73	5	PS50294
Domain	Galactose-bd-like	ALLC NGLY1 HERC2	5.95e-03	94	73	3	IPR008979
Domain	PROTEIN_KINASE_TYR	OBSCN LYN YES1	6.49e-03	97	73	3	PS00109
Domain	Tyr_kinase_AS	OBSCN LYN YES1	6.49e-03	97	73	3	IPR008266
Domain	Actin	POTEI ACTRT1	6.51e-03	31	73	2	IPR004000
Domain	Actin	POTEI ACTRT1	6.51e-03	31	73	2	PF00022
Domain	ACTIN	POTEI ACTRT1	6.51e-03	31	73	2	SM00268
Domain	SH2	NCK1 LYN YES1	7.26e-03	101	73	3	PF00017
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K	2.30e-10	99	58	9	M46448
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION	AMBRA1 ATG14	2.47e-04	6	58	2	M47662
Pathway	REACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS	PAPSS2 PAPSS1	2.47e-04	6	58	2	MM14679
Pathway	REACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS	PAPSS2 PAPSS1	2.47e-04	6	58	2	M27027
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION	AMBRA1 ATG14	2.47e-04	6	58	2	M47681
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.54e-30	11	76	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F	2.87e-10	74	76	7	16625196
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	4.00e-08	4	76	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	4.00e-08	4	76	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	1.00e-07	5	76	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	1.00e-07	5	76	3	8471161
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	CAPN2 RYR1 RYR2	3.49e-07	7	76	3	20962236
Pubmed	The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.	NCK1 LYN YES1	5.57e-07	8	76	3	21309750
Pubmed	Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction.	BMPR1A BMPR1B SPI1	1.19e-06	10	76	3	21571370
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	SNX18 NCK1 LYN YES1	4.49e-06	50	76	4	19807924
Pubmed	A member of a family of sulfate-activating enzymes causes murine brachymorphism.	PAPSS2 PAPSS1	4.71e-06	2	76	2	9671738
Pubmed	Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.	BMPR1A BMPR1B	4.71e-06	2	76	2	15102710
Pubmed	Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.	BMPR1A BMPR1B	4.71e-06	2	76	2	9730621
Pubmed	Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.	BMPR1A BMPR1B	4.71e-06	2	76	2	10850425
Pubmed	Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.	BMPR1A BMPR1B	4.71e-06	2	76	2	28357470
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	4.71e-06	2	76	2	17259277
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	4.71e-06	2	76	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	4.71e-06	2	76	2	26009179
Pubmed	Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).	BMPR1A BMPR1B	4.71e-06	2	76	2	15322331
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	4.71e-06	2	76	2	32899693
Pubmed	Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.	PAPSS2 PAPSS1	4.71e-06	2	76	2	10657990
Pubmed	Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.	PAPSS2 PAPSS1	4.71e-06	2	76	2	10679223
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	4.71e-06	2	76	2	30542613
Pubmed	Circadian amplitude of cryptochrome 1 is modulated by mRNA stability regulation via cytoplasmic hnRNP D oscillation.	HNRNPD CRY1	4.71e-06	2	76	2	19858287
Pubmed	Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains.	GPNMB RYR1	4.71e-06	2	76	2	21933672
Pubmed	Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.	PAPSS2 PAPSS1	4.71e-06	2	76	2	9771708
Pubmed	BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.	BMPR1A BMPR1B	4.71e-06	2	76	2	31769494
Pubmed	Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.	PAPSS2 PAPSS1	4.71e-06	2	76	2	11931637
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	4.71e-06	2	76	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	4.71e-06	2	76	2	11673493
Pubmed	BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.	BMPR1A BMPR1B	4.71e-06	2	76	2	32764110
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	4.71e-06	2	76	2	11673462
Pubmed	[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].	BMPR1A BMPR1B	4.71e-06	2	76	2	20673479
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	4.71e-06	2	76	2	25370123
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	4.71e-06	2	76	2	15033925
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	4.71e-06	2	76	2	18618700
Pubmed	Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.	PAPSS2 PAPSS1	4.71e-06	2	76	2	22242175
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	1.41e-05	3	76	2	18403125
Pubmed	Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.	BMPR1A BMPR1B	1.41e-05	3	76	2	15897891
Pubmed	The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.	YES1 HNRNPD	1.41e-05	3	76	2	16289864
Pubmed	Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.	BMPR1A BMPR1B	1.41e-05	3	76	2	26584636
Pubmed	Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.	BMPR1A BMPR1B	1.41e-05	3	76	2	25538007
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2	1.41e-05	3	76	2	18434746
Pubmed	Differential mitotic activation of endogenous c-Src, c-Yes, and Lyn in HeLa cells.	LYN YES1	1.41e-05	3	76	2	17692281
Pubmed	Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor.	LYN YES1	1.41e-05	3	76	2	22430206
Pubmed	Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.	BMPR1A BMPR1B	1.41e-05	3	76	2	24048844
Pubmed	Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.	BMPR1A BMPR1B	1.41e-05	3	76	2	15673568
Pubmed	Expression of bone morphogenetic protein receptors in the developing mouse metanephros.	BMPR1A BMPR1B	1.41e-05	3	76	2	11701996
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2	1.41e-05	3	76	2	9204703
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	1.41e-05	3	76	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2	1.41e-05	3	76	2	21881589
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	1.41e-05	3	76	2	24123915
Pubmed	Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.	BMPR1B OBSCN	1.41e-05	3	76	2	31098411
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	1.41e-05	3	76	2	21030649
Pubmed	Expression patterns of BMPRs in the developing mouse molar.	BMPR1A BMPR1B	1.41e-05	3	76	2	16432712
Pubmed	Analysis of the native murine bone morphogenetic protein serine threonine kinase type I receptor (ALK-3).	BMPR1A BMPR1B	1.41e-05	3	76	2	8707881
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2	1.41e-05	3	76	2	12213830
Pubmed	The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.	BMPR1A BMPR1B	1.41e-05	3	76	2	11714695
Pubmed	Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.	RYR1 RYR2	1.41e-05	3	76	2	23278119
Pubmed	Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.	BMPR1A BMPR1B	1.41e-05	3	76	2	23831617
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2	1.41e-05	3	76	2	9242641
Pubmed	The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.	BMPR1A BMPR1B	1.41e-05	3	76	2	25413979
Pubmed	Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.	BMPR1A BMPR1B	1.41e-05	3	76	2	20363875
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2	1.41e-05	3	76	2	22948152
Pubmed	Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.	RYR1 RYR2	1.41e-05	3	76	2	23454728
Pubmed	The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors.	BMPR1A BMPR1B	1.41e-05	3	76	2	19726563
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2	1.41e-05	3	76	2	10788707
Pubmed	BMP signaling specifies the development of a large and fast CNS synapse.	BMPR1A BMPR1B	1.41e-05	3	76	2	23708139
Pubmed	Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.	BMPR1A BMPR1B	1.41e-05	3	76	2	7750489
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2	1.41e-05	3	76	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2	1.41e-05	3	76	2	7621815
Pubmed	BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.	BMPR1A BMPR1B	1.41e-05	3	76	2	20130193
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2	1.41e-05	3	76	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2	1.41e-05	3	76	2	11159936
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR1 RYR2	1.41e-05	3	76	2	9986730
Pubmed	Inceptor facilitates acrosomal vesicle formation in spermatids and is required for male fertility.	BMPR1B ELAPOR1	1.41e-05	3	76	2	37691832
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2	1.41e-05	3	76	2	10473538
Pubmed	Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.	BMPR1A BMPR1B	1.41e-05	3	76	2	8605097
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2	1.41e-05	3	76	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2	1.41e-05	3	76	2	4600883
Pubmed	Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation.	BMPR1A BMPR1B	1.41e-05	3	76	2	8592941
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2	1.41e-05	3	76	2	7635066
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	NCK1 LYN YES1	2.23e-05	25	76	3	16374509
Pubmed	Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.	BMPR1A BMPR1B	2.82e-05	4	76	2	21152263
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2	2.82e-05	4	76	2	18206662
Pubmed	Oligomeric interactions of TGF-β and BMP receptors.	BMPR1A BMPR1B	2.82e-05	4	76	2	22293501
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 RYR2	2.82e-05	4	76	2	22504960
Pubmed	Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors.	BMPR1A BMPR1B	2.82e-05	4	76	2	10712517
Pubmed	Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase.	HERC2 CRY1	2.82e-05	4	76	2	20304803
Pubmed	Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse.	BMPR1A BMPR1B	2.82e-05	4	76	2	18614674
Pubmed	Common genetic variants of the BMP4, BMPR1A, BMPR1B, and ACVR1 genes, left ventricular mass, and other parameters of the heart in newborns.	BMPR1A BMPR1B	2.82e-05	4	76	2	22971142
Pubmed	Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma.	BMPR1A BMPR1B	2.82e-05	4	76	2	11401330
Pubmed	HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression.	BMPR1A BMPR1B	2.82e-05	4	76	2	24904118
Pubmed	LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling.	BMPR1A BMPR1B	2.82e-05	4	76	2	32572071
Pubmed	A unique role for Fyn in CNS myelination.	LYN YES1	2.82e-05	4	76	2	11245687
Pubmed	Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.	RYR1 RYR2	2.82e-05	4	76	2	23992453
Pubmed	Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly.	BMPR1A BMPR1B	2.82e-05	4	76	2	17913790
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2	2.82e-05	4	76	2	23413940
Pubmed	Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.	LYN YES1	2.82e-05	4	76	2	19258394
Pubmed	p21rasGAP association with Fyn, Lyn, and Yes in thrombin-activated platelets.	LYN YES1	2.82e-05	4	76	2	1544885
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.38e-15	149	76	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	6.89e-07	99	76	5	17q12
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	1.43e-05	3	40	2	287
GeneFamily	Type 1 receptor serine/threonine kinases	BMPR1A BMPR1B	9.95e-05	7	40	2	345
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM9 PRDM7	6.36e-04	17	40	2	1197
GeneFamily	SH2 domain containing	NCK1 LYN YES1	1.44e-03	101	40	3	741
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.59e-11	90	74	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.46e-08	213	74	9	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.46e-08	213	74	9	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.62e-07	242	74	9	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.71e-07	281	74	9	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.71e-07	281	74	9	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.68e-06	320	74	9	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	gallbladder	ACE2 HHLA2 TBC1D3E LMO7DN ARL14	1.68e-04	148	74	5	gallbladder
CoexpressionAtlas	small intestine	ACE2 HHLA2 GLOD5 TBC1D3 TBC1D3D SLC28A2 APOBEC1	1.79e-04	339	74	7	small intestine
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	LPIN3 HHLA2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D KLHDC2 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.56e-04	1049	74	12	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132 RYR1	5.88e-06	150	76	5	b37f538ca5f976b509efe35dc81115b72b227084
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132 RYR1	5.88e-06	150	76	5	2c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132 RYR1	1.08e-05	170	76	5	4d28dc9eb572f43809619f923978cd7494853d43
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132 RYR1	1.11e-05	171	76	5	ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACE2 TBC1D3L TBC1D3D ELAPOR1 PRDM7	1.46e-05	181	76	5	c1fad1f03468523e563c039be520dcf7717f90cd
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPI1 GPNMB LYN GPR132 RYR1	1.85e-05	190	76	5	e0b363f772817cfc6ab425430805c1cddcba23f0
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LPIN3 CRYBA4 ACE2 SPI1	2.04e-05	94	76	4	d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LPIN3 CRYBA4 ACE2 SPI1	2.04e-05	94	76	4	dfc3f7977b9df433009d1d2d465b64a2de5806e2
ToppCell	Club_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	BMPR1B ELAPOR1 SLC28A2 ARL14	9.16e-05	138	76	4	133015953fc660d00339f47b415da5e9872313a2
ToppCell	P03-Hematopoietic\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GLOD5 SPI1 GPR132 RYR1	9.95e-05	141	76	4	4a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 GPR132 RYR1	1.05e-04	143	76	4	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 GPR132 RYR1	1.05e-04	143	76	4	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	P03-Hematopoietic-Immune-immune_cell_unspecified\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GLOD5 SPI1 GPNMB GPR132	1.23e-04	149	76	4	43d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCell	P03-Hematopoietic-Immune\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GLOD5 SPI1 GPNMB GPR132	1.23e-04	149	76	4	1c5a2572741c47246d455c865e8e1677c9f49598
ToppCell	droplet-Fat-Scat-21m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D SPI1 GPR132 RYR1	1.30e-04	151	76	4	79827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCell	Myeloid-C_(Monocyte)\|World / shred on cell class and cell subclass (v4)	SPI1 BRI3BP LYN GPR132	1.33e-04	152	76	4	9145dc014ed7f154c158d454dc2b9754396afcca
ToppCell	primary_visual_cortex-Non-neuronal-macrophage-Macrophage\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYBA4 SPI1 APOBEC1 LYN	1.47e-04	156	76	4	4b6b59a1638a7218a9ed9bd702c04d9f51dbc7aa
ToppCell	primary_visual_cortex-Non-neuronal-macrophage\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYBA4 SPI1 APOBEC1 LYN	1.47e-04	156	76	4	60a8a8584d3c80c4ceb433cb820de914e33e3500
ToppCell	frontal_cortex-Non-neuronal-macrophage-Macrophage-Microglia_Siglech\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYBA4 SPI1 APOBEC1 LYN	1.62e-04	160	76	4	c3f2f362e5d0602bb997e8367b4c9a8fe88e4ea8
ToppCell	droplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP APOBEC1 GPR132	1.62e-04	160	76	4	0b8151037b28f52a21918856a1e9336e8d5edb90
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	1.62e-04	160	76	4	6329b0f02f9509086e563c2ed762a8ec693883b5
ToppCell	droplet-Lung-nan-21m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP APOBEC1 GPR132	1.62e-04	160	76	4	4738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SCPEP1 ROBO3 RYR1	1.66e-04	161	76	4	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SCPEP1 ROBO3 RYR1	1.66e-04	161	76	4	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|367C / Donor, Lineage, Cell class and subclass (all cells)	CRYBA4 KLRF1 SLC28A2 YES1	1.70e-04	162	76	4	59c0dcb5b51c1803660aeec51b60deceeeaeea66
ToppCell	frontal_cortex-Non-neuronal-macrophage\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYBA4 SPI1 APOBEC1 LYN	1.74e-04	163	76	4	b89f586b444f90047c8ce407f53847fd1ee7cca3
ToppCell	frontal_cortex-Non-neuronal-macrophage-Macrophage\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYBA4 SPI1 APOBEC1 LYN	1.74e-04	163	76	4	cbe9b4c4b2e42e9f92a57ed66758af93434db5bb
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CRYBA4 KLRF1 SLC28A2 YES1	1.74e-04	163	76	4	6c4d4c55fc8a731acca13c1ba7287f238a9d81e0
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN RYR1	1.74e-04	163	76	4	bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCell	droplet-Bladder-nan-3m-Hematologic-leukocyte\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	1.74e-04	163	76	4	2f32a9ab0230fdca98ffa7fd59397301d50e4f30
ToppCell	droplet-Bladder-nan-3m-Hematologic\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	1.74e-04	163	76	4	6c2967dee563295febe2adabf503d095cb911ccf
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN RYR1	1.78e-04	164	76	4	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 GPR132	1.78e-04	164	76	4	cd0794f84dfd346807e2d803723718b7f22e9232
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 GPR132	1.78e-04	164	76	4	12251a49fd4af32d4edb58046245548c260cf04b
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN RYR1	1.78e-04	164	76	4	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 LYN GPR132 RYR1	1.78e-04	164	76	4	5ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN RYR1	1.78e-04	164	76	4	11dfd84f5fb90de330858e1e852848832734e004
ToppCell	droplet-Lung-nan-18m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	1.82e-04	165	76	4	e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DMTF1 BMPR1B ELAPOR1 CHRNA1	1.82e-04	165	76	4	f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell	droplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	1.82e-04	165	76	4	0fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCell	droplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	1.86e-04	166	76	4	dd5944101ef58a9a29aa3eb5c17690119572b8f1
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	1.86e-04	166	76	4	8e5e8de51b4dacdadaa5a08279df30b5c7ed3628
ToppCell	facs-Lung-3m-Hematologic-myeloid\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	1.86e-04	166	76	4	7bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCell	droplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	1.86e-04	166	76	4	e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPI1 BRI3BP APOBEC1 GPR132	1.91e-04	167	76	4	8aacb102c1b0067a86eb6c2acedd07667198487d
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBA4 SPI1 APOBEC1 LYN	1.91e-04	167	76	4	d62d5dec30d006a9cc8f3bc5ccc578e10f105027
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRDM9 SPI1 GPR132 RYR1	1.91e-04	167	76	4	fd84a99ea142d1684cdcf4a88ef1d541760bc78a
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l17-15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	1.95e-04	168	76	4	798b619a9270eed8301959fbce7bb95d445a7341
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	1.95e-04	168	76	4	a6992b9cc003e4d45d800767d94de5d7a193fc32
ToppCell	droplet-Bladder-BLADDER-1m-Hematologic-leukocyte\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.00e-04	169	76	4	b46e446067c6425bd5b8ef7719aeecff5e861249
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 LYN	2.00e-04	169	76	4	90c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCell	droplet-Trachea-nan-3m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	2.00e-04	169	76	4	58590137dce1420c74c56fce07a1c0151132a37e
ToppCell	droplet-Bladder-BLADDER-1m-Hematologic\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.00e-04	169	76	4	5508b03fbf483fce7701d6c82c297ffda3b1ba05
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	2.00e-04	169	76	4	ae975e982faf2f161fbba8edb919981e54d9ce17
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPI1 BRI3BP APOBEC1 GPR132	2.04e-04	170	76	4	a6f2a792980e6a1025b8f1b0eda442a555938488
ToppCell	droplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.04e-04	170	76	4	29deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	2.04e-04	170	76	4	e4856e768d0088e42fbdb8e6039f5bc3daa0afdb
ToppCell	droplet-Thymus-nan-21m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.04e-04	170	76	4	dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP GPR132 RYR1	2.04e-04	170	76	4	6686d1797988216c0d9417f21a2537369abce410
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 LYN GPR132 RYR1	2.09e-04	171	76	4	87cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCell	droplet-Thymus-nan-21m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.09e-04	171	76	4	8bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP GPR132 RYR1	2.09e-04	171	76	4	0385d5834ae16bbb0c6a68893fec60e4dd1e478d
ToppCell	droplet-Lung-21m-Hematologic-myeloid\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 LYN	2.09e-04	171	76	4	22ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP GPR132 RYR1	2.09e-04	171	76	4	a3e3fe0cbab21abb178c482f5951e576529f7e30
ToppCell	droplet-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.14e-04	172	76	4	f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 LYN GPR132 RYR1	2.14e-04	172	76	4	f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell	NS-critical-d_0-4-Epithelial-FOXN4+\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LPIN3 ACE2 ELAPOR1 WDR24	2.14e-04	172	76	4	a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell	facs-Trachea-nan-24m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 APOBEC1 LYN GPR132	2.14e-04	172	76	4	40b4313dd6081d0a48fc3d0a5cb8ead4d646aae0
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP GPR132 RYR1	2.14e-04	172	76	4	e680abead2da75e50774da02384eb2729c839c01
ToppCell	facs-Trachea-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	2.14e-04	172	76	4	c260680f5455fce133b7b4158b4197fc76115779
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.23e-04	174	76	4	2f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 APOBEC1 LYN GPR132	2.23e-04	174	76	4	d67fc8e30cc67fff8f7fdeaccb409d12ca0992c1
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D3L SPI1 GPNMB PRDM7	2.23e-04	174	76	4	75b3a852140fb726025c3c987143d67944afde2d
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.23e-04	174	76	4	01eff218e71a04201189a0313aaf91437fffed95
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP GPR132 RYR1	2.23e-04	174	76	4	c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 SCPEP1 LYN RYR1	2.23e-04	174	76	4	f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPI1 GPNMB LYN GPR132	2.33e-04	176	76	4	98176bf3c961d5262593e2d5d002836adb010e13
ToppCell	facs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP GPR132 RYR1	2.38e-04	177	76	4	7bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 LYN	2.49e-04	179	76	4	66afd54428e6dcadc3e341faecfde42be4fb5905
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP GPR132 RYR1	2.49e-04	179	76	4	33ed9270d257895ff3b40df2c1af878119c9f492
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP APOBEC1 LYN	2.49e-04	179	76	4	fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPI1 BRI3BP GPR132 RYR1	2.49e-04	179	76	4	55fde77dae7f9e7f3431c3185d14212a25af83df
ToppCell	droplet-Pancreas-Endocrine-21m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.54e-04	180	76	4	83f9060dcf1d0ff8d2b2edc1841b2624b81c0eb3
ToppCell	droplet-Pancreas-Endocrine-21m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.65e-04	182	76	4	cf32603ad9b9882b0bb873327d58b50dd26a5bd3
ToppCell	droplet-Pancreas-Endocrine-21m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 LYN GPR132 RYR1	2.65e-04	182	76	4	71cfd0b6d464e3e1b1cca34f423abdf699cda48a
ToppCell	facs-Heart-LA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCPEP1 APOBEC1 GPNMB GABRA3	2.65e-04	182	76	4	47b747722766dbcc6a73673e99ee5f938b82b890
ToppCell	facs-Lung-EPCAM-24m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 BRI3BP GPR132 RYR1	2.70e-04	183	76	4	f524501dec1dccbf44100a61395116e4525bdc89
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-mature_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LPIN3 CRYBA4 BMPR1A KLRF1	2.70e-04	183	76	4	8746e6ecc6bf9e194cc9cdf9b07da63f0fcf8b5f
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KLRF1 PNLDC1 LYN YES1	2.82e-04	185	76	4	25781cf68e693e97dc1885e2879ab24fa946b51e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPI1 GPNMB LYN RYR1	3.06e-04	189	76	4	b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPI1 LYN GPR132 RYR1	3.06e-04	189	76	4	440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	SNX18 LYN PAPSS2 HERC2P3	3.12e-04	190	76	4	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	SNX18 LYN PAPSS2 HERC2P3	3.12e-04	190	76	4	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SPI1 GPNMB GPR132 RYR1	3.12e-04	190	76	4	912aa106581d1ed7e147c92f9a367e8e6b04052b
ToppCell	droplet-Marrow-nan-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRI3BP CAPN2 SCPEP1 PAPSS2	3.12e-04	190	76	4	e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPI1 LYN GPR132 RYR1	3.18e-04	191	76	4	c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCell	10x5'-Lung-Myeloid_Monocytic-Nonclassical_monocytes\|Lung / Manually curated celltypes from each tissue	SPI1 SNX18 LYN PAPSS2	3.18e-04	191	76	4	a862a571625ab7238589ff201e5954f602c3bd7e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPI1 SCPEP1 GPNMB LYN	3.18e-04	191	76	4	b5715eeb72a97b7bc87b83f6c289e225f58da842
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	SPI1 GPNMB LYN PAPSS1	3.24e-04	192	76	4	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	COPD-Myeloid-ncMonocyte\|COPD / Disease state, Lineage and Cell class	SNX18 LYN PAPSS2 HERC2P3	3.31e-04	193	76	4	936ca95995599356b794fba32bfd82d8de339365
Drug	AC1MW7VF	EIF4E NGLY1 RYR1 RYR2	2.73e-07	19	68	4	CID000414699
Drug	selenite	CRYBA4 CAPN2 PAPSS2 PAPSS1 RYR1 RYR2	5.35e-06	148	68	6	CID000001090
Drug	adenosine 5'-phosphoselenate	PAPSS2 PAPSS1	8.79e-06	2	68	2	CID000440758
Drug	beta-methylene-APS	PAPSS2 PAPSS1	8.79e-06	2	68	2	CID000129324
Drug	4-octylphenol	TAF2 PAPSS2 PAPSS1 YES1	1.18e-05	47	68	4	CID000015730
Drug	2-hydroxycarbazole	RYR1 RYR2	2.63e-05	3	68	2	CID000093551
Drug	cis-diammineplatinum(II	RYR1 RYR2	2.63e-05	3	68	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR2	2.63e-05	3	68	2	CID002750949
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR2	2.63e-05	3	68	2	CID005748312
Drug	8N3-cADPR	RYR1 RYR2	2.63e-05	3	68	2	CID000127713
Drug	aminodantrolene	RYR1 RYR2	2.63e-05	3	68	2	CID009570289
Drug	NSC178249	EIF4E YES1 RYR1	3.26e-05	21	68	3	CID005351257
Drug	PCB74	RYR1 RYR2	5.25e-05	4	68	2	CID000036218
Drug	148504-47-6	RYR1 RYR2	5.25e-05	4	68	2	CID006444275
Drug	SC 38249	RYR1 RYR2	5.25e-05	4	68	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR2	5.25e-05	4	68	2	CID000035682
Drug	AC1MIY5S	PAPSS2 PAPSS1	8.74e-05	5	68	2	CID003082099
Drug	A 68930	RYR1 RYR2	8.74e-05	5	68	2	ctd:C065380
Drug	acetylthiocholine	ACE2 GPR132 CHRNA1	8.81e-05	29	68	3	CID000020544
Drug	MW 1	BMPR1A BMPR1B SPI1 RYR1 RYR2	8.94e-05	151	68	5	CID000073965
Drug	M3/M4	CHRNA1 RYR1 RYR2	1.19e-04	32	68	3	CID000486507
Drug	MBED	RYR1 RYR2	1.31e-04	6	68	2	CID000129958
Drug	chloro-m-cresol	RYR1 RYR2	1.31e-04	6	68	2	CID000012008
Drug	AC1O528X	RYR1 RYR2	1.31e-04	6	68	2	CID006475857
Drug	NSC114784	RYR1 RYR2	1.31e-04	6	68	2	CID000419425
Drug	lavendustin A	EIF4E LYN YES1 RYR1 RYR2	1.60e-04	171	68	5	CID000003894
Drug	17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A	CAPN2 PAPSS2 AHSA1 GPR132 HNRNPD	1.74e-04	174	68	5	2673_UP
Drug	Azumoleno	RYR1 RYR2	1.83e-04	7	68	2	CID000056259
Drug	Br2BAPTA	RYR1 RYR2	1.83e-04	7	68	2	CID003081001
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR2	1.83e-04	7	68	2	CID009547999
Drug	1,2-dichlorohexafluorocyclobutane	CHRNA1 RYR1 RYR2	1.84e-04	37	68	3	CID000009643
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A	CAPN2 PAPSS2 AHSA1 GPR132 HNRNPD	1.88e-04	177	68	5	2679_UP
Drug	richter	ACE2 SPI1 GPNMB	1.99e-04	38	68	3	CID003032626
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	1.43e-05	3	65	2	DOID:8545 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	1.43e-05	3	65	2	DOID:3529 (implicated_via_orthology)
Disease	colorectal cancer (implicated_via_orthology)	SNX18 LYN YES1	3.97e-05	30	65	3	DOID:9256 (implicated_via_orthology)
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	CHRNA1 RYR1	7.13e-05	6	65	2	C1854678
Disease	juvenile polyposis syndrome (implicated_via_orthology)	BMPR1A BMPR1B	3.67e-04	13	65	2	DOID:0050787 (implicated_via_orthology)
Disease	Eye Abnormalities	BMPR1A BMPR1B	6.36e-04	17	65	2	C0015393
Disease	CCL4 measurement	TBC1D3 TBC1D3F	8.85e-04	20	65	2	EFO_0004751
Disease	alcohol use disorder (implicated_via_orthology)	SPI1 CHRNA1 RYR1 RYR2	9.14e-04	195	65	4	DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KCGIWGWRSEKMETV	ANKRD13D	246	Q6ZTN6
VLGVDMFVETLWKVW	BRI3BP	81	Q8WY22
EIKWGMSRKIWRSSG	APOBEC1	41	P41238
RGRMIKWFWDSAEEG	ACCS	66	Q96QU6
EGKWITDQLRWKIMS	ATG14	101	Q6ZNE5
EFGKWMDGWETRRKR	ALLC	41	Q8N6M5
MAKWGEGDPRWIVEE	AHSA1	1	O95433
DMRWKNSWKGGRVQA	GPNMB	66	Q14956
TVWDVGGQEKMRTVW	ARL14	61	Q8N4G2
ELVEDKTRWMKWEGK	AMBRA1	31	Q9C0C7
GEVWMGKWRGEKVAV	BMPR1B	216	O00238
WKQGMWSKEEIDILM	DMTF1	151	Q9Y222
KEKGEVGKSWDSWSD	RAB3GAP1	566	Q15042
DIWNKTGAVKLMRWS	RIC1	301	Q4ADV7
MESGEWVIKESRGWK	CHRNA1	191	P02708
GWTKDDDVPLDWRMK	PAPSS2	446	O95340
EREKMPRKGGRWWFS	LPIN3	516	Q9BQK8
KDVRGAVKRLMGWEW	OR2J1	296	Q9GZK6
GWENGVWKMESIFRK	NGLY1	516	Q96IV0
TKVIVMEKCSDGWWR	NCK1	131	P16333
SMWHRKWVLGKEDLE	NLRP8	461	Q86W28
VKMWGRTLEKQSWRD	GLOD5	11	A6NK44
TRVMRGVDWKWGDQD	HERC2	1871	O95714
MISLEVRWWIKGKQG	LMO7DN	46	F2Z398
DDSRWMKTTEKGWEF	ELAPOR1	216	Q6UXG2
MWEDEKNKRGGRWLI	EIF4E	101	P06730
CKEWQRVISEGMLWK	FBXW11	151	Q9UKB1
LLKQTWTGRWTMKDG	HHLA2	216	Q9UM44
SWAWEGKKVPEALEM	GABRA3	366	P34903
EEFREGLKGVWKWMI	GPR151	311	Q8TDV0
RCELSKMAPVEWWKG	OBSCN	3646	Q5VST9
TKEEWAEMGDWEKTR	PRDM9	36	Q9NQV7
GWTKDDDVPLMWRMK	PAPSS1	456	O43252
KMTWTWVDGSPIDSK	KLRF1	181	Q9NZS2
TRGDLWISWEEGMKV	CRY1	366	Q16526
GEVWMGKWRGEKVAV	BMPR1A	246	P36894
KWWEMKREIVGVVEP	ACE2	476	Q9BYF1
TKSAGPWKMVVWDED	CRYBA4	6	P53673
KGEKMKVLEEHGEWW	LYN	86	P07948
EELWIYNMETGRWKK	KLHDC2	66	Q9Y2U9
WKLTKMDGNWRRGST	CAPN2	356	P17655
SVERGMSWEEATKIW	SBNO1	1181	A3KN83
MIAWEWTIEKAREGE	RYR1	2816	P21817
KESLKTMLAWGWRIE	RYR2	2776	Q92736
GVYVWGETWEKAKTM	APIP	196	Q96GX9
RIHKGWKEWSMKTDV	GPR132	321	Q9UNW8
EWKMFIGGLSWDTTK	HNRNPD	96	Q14103
TMGQEAWVRKLKWPE	SCPEP1	376	Q9HB40
RMSWSDEWVLKGISG	TAF2	361	Q6P1X5
EVTRWLELAKEGDWM	PNLDC1	156	Q8NA58
TKEEWAEMGDWEKTR	PRDM7	36	Q9NQW5
AAWWGKVARKDLIVM	POTEI	146	P0CG38
RSGDMKDSIWWVDKD	SPI1	181	P17947
KIGTRVMRGVDWKWG	HERC2P3	596	Q9BVR0
EISRKSKWVDMLGDW	TBC1D3L	71	B9A6J9
RLSGMEEWIEGEKQW	SLC28A2	506	O43868
RGLVTGWDDMEKLWK	ACTRT1	76	Q8TDG2
EISRKSKWVDMLGDW	TBC1D3B	71	A6NDS4
EISRKSKWVDMLGDW	TBC1D3H	71	P0C7X1
EISRKSKWVDMLGDW	TBC1D3F	71	A6NER0
EDFISKRRKGLIWWM	SNX18	346	Q96RF0
STGEATWSGWLKMRE	ROBO3	526	Q96MS0
EISRKSKWVDMLGDW	TBC1D3E	71	A0A087X179
EISRKSKWVDMLGDW	TBC1D3D	71	A0A087WVF3
GWLATGGRDKMVKVW	WDR24	221	Q96S15
EISRKSKWVDMLGDW	TBC1D3G	71	Q6DHY5
EISRKSKWVDMLGDW	TBC1D3	71	Q8IZP1
EISRKSKWVDMLGDW	TBC1D3K	71	A0A087X1G2
EISRKSKWVDMLGDW	TBC1D3I	71	A0A087WXS9
EISRKSKWVDMLGDW	TBC1D3C	71	Q6IPX1
GKEPWMVVREETGRW	ZNF461	61	Q8TAF7
SKGMIPDWESRWENK	ZNF181	71	Q2M3W8
MKSGWGELSASTEWK	TNRC6B	676	Q9UPQ9
VWMGTWNGTTKVAIK	YES1	291	P07947
SHTWVKEGKRPWGEM	GARIN5B	761	Q8N5Q1
KRTLMDDNKVLWGSW	NAPEPLD	256	Q6IQ20