Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen synthase activity, transferring glucose-1-phosphate	GYS1 GYS2	1.63e-06	2	26	2	GO:0061547
GeneOntologyMolecularFunction	alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity	GYS1 GYS2	4.89e-06	3	26	2	GO:0004373
GeneOntologyMolecularFunction	UDP-glucosyltransferase activity	GYS1 GYS2	1.26e-04	13	26	2	GO:0035251
GeneOntologyMolecularFunction	cytidine deaminase activity	APOBEC3B APOBEC3F	1.26e-04	13	26	2	GO:0004126
GeneOntologyMolecularFunction	D-glucose binding	GYS1 GYS2	1.47e-04	14	26	2	GO:0005536
GeneOntologyMolecularFunction	peptidase activity	PSMB8 DPP4 PRPF8 F3 MMP28 TMPRSS6	1.59e-04	654	26	6	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	PSMB8 DPP4 F3 MMP28 TMPRSS6	2.05e-04	430	26	5	GO:0004175
GeneOntologyMolecularFunction	glucosyltransferase activity	GYS1 GYS2	3.71e-04	22	26	2	GO:0046527
GeneOntologyMolecularFunction	deaminase activity	APOBEC3B APOBEC3F	8.91e-04	34	26	2	GO:0019239
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	APOBEC3B APOBEC3F	9.99e-04	36	26	2	GO:0016814
GeneOntologyMolecularFunction	serine-type endopeptidase activity	DPP4 F3 TMPRSS6	1.88e-03	190	26	3	GO:0004252
GeneOntologyMolecularFunction	metallopeptidase activity	PRPF8 MMP28 TMPRSS6	2.17e-03	200	26	3	GO:0008237
GeneOntologyMolecularFunction	serine-type peptidase activity	DPP4 F3 TMPRSS6	2.39e-03	207	26	3	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	DPP4 F3 TMPRSS6	2.56e-03	212	26	3	GO:0017171
GeneOntologyMolecularFunction	monosaccharide binding	GYS1 GYS2	6.76e-03	95	26	2	GO:0048029
GeneOntologyBiologicalProcess	clearance of foreign intracellular DNA	APOBEC3B APOBEC3F	2.47e-05	6	27	2	GO:0044355
GeneOntologyBiologicalProcess	clearance of foreign intracellular nucleic acids	APOBEC3B APOBEC3F	2.47e-05	6	27	2	GO:0099046
GeneOntologyBiologicalProcess	DNA cytosine deamination	APOBEC3B APOBEC3F	7.38e-05	10	27	2	GO:0070383
GeneOntologyBiologicalProcess	cytidine to uridine editing	APOBEC3B APOBEC3F	1.08e-04	12	27	2	GO:0016554
GeneOntologyBiologicalProcess	cytidine metabolic process	APOBEC3B APOBEC3F	1.49e-04	14	27	2	GO:0046087
GeneOntologyBiologicalProcess	cytidine catabolic process	APOBEC3B APOBEC3F	1.49e-04	14	27	2	GO:0006216
GeneOntologyBiologicalProcess	cytidine deamination	APOBEC3B APOBEC3F	1.49e-04	14	27	2	GO:0009972
GeneOntologyBiologicalProcess	DNA deamination	APOBEC3B APOBEC3F	1.49e-04	14	27	2	GO:0045006
GeneOntologyBiologicalProcess	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	1.96e-04	16	27	2	GO:0045869
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside metabolic process	APOBEC3B APOBEC3F	1.96e-04	16	27	2	GO:0046131
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside catabolic process	APOBEC3B APOBEC3F	1.96e-04	16	27	2	GO:0046133
GeneOntologyBiologicalProcess	pyrimidine nucleoside catabolic process	APOBEC3B APOBEC3F	2.49e-04	18	27	2	GO:0046135
GeneOntologyBiologicalProcess	regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	2.78e-04	19	27	2	GO:0045091
GeneOntologyBiologicalProcess	base conversion or substitution editing	APOBEC3B APOBEC3F	2.78e-04	19	27	2	GO:0016553
GeneOntologyBiologicalProcess	single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	3.09e-04	20	27	2	GO:0039692
GeneOntologyBiologicalProcess	negative regulation of leukocyte chemotaxis	DPP4 MMP28	4.10e-04	23	27	2	GO:0002689
GeneOntologyBiologicalProcess	ribonucleoside catabolic process	APOBEC3B APOBEC3F	5.26e-04	26	27	2	GO:0042454
GeneOntologyBiologicalProcess	pyrimidine nucleoside metabolic process	APOBEC3B APOBEC3F	5.68e-04	27	27	2	GO:0006213
GeneOntologyBiologicalProcess	DNA modification	APOBEC3B APOBEC3F	7.50e-04	31	27	2	GO:0006304
GeneOntologyBiologicalProcess	viral RNA genome replication	APOBEC3B APOBEC3F	7.99e-04	32	27	2	GO:0039694
GeneOntologyBiologicalProcess	nucleoside catabolic process	APOBEC3B APOBEC3F	7.99e-04	32	27	2	GO:0009164
GeneOntologyBiologicalProcess	nucleobase-containing small molecule catabolic process	APOBEC3B APOBEC3F	1.07e-03	37	27	2	GO:0034656
GeneOntologyBiologicalProcess	glycosyl compound catabolic process	APOBEC3B APOBEC3F	1.31e-03	41	27	2	GO:1901658
GeneOntologyBiologicalProcess	transposable element silencing	APOBEC3B APOBEC3F	1.65e-03	46	27	2	GO:0010526
GeneOntologyBiologicalProcess	pyrimidine-containing compound catabolic process	APOBEC3B APOBEC3F	1.65e-03	46	27	2	GO:0072529
GeneOntologyBiologicalProcess	ribonucleoside metabolic process	APOBEC3B APOBEC3F	1.79e-03	48	27	2	GO:0009119
GeneOntologyBiologicalProcess	retrotransposition	APOBEC3B APOBEC3F	1.79e-03	48	27	2	GO:0032197
GeneOntologyBiologicalProcess	transposition	APOBEC3B APOBEC3F	1.94e-03	50	27	2	GO:0032196
MousePheno	abnormal glycogen catabolism	GYS1 GYS2	1.41e-04	11	23	2	MP:0002713
MousePheno	decreased susceptibility to Ortervirales infection	APOBEC3B APOBEC3F	1.69e-04	12	23	2	MP:0020920
MousePheno	increased susceptibility to Retroviridae infection	APOBEC3B APOBEC3F	1.69e-04	12	23	2	MP:0020934
MousePheno	decreased susceptibility to Retroviridae infection	APOBEC3B APOBEC3F	1.69e-04	12	23	2	MP:0020935
MousePheno	increased susceptibility to Ortervirales infection	APOBEC3B APOBEC3F	2.00e-04	13	23	2	MP:0020919
MousePheno	internal hemorrhage	WDR91 DPP4 FLT4 F3 GYS1	3.53e-04	387	23	5	MP:0001634
MousePheno	abnormal susceptibility to Retroviridae infection	APOBEC3B APOBEC3F	4.35e-04	19	23	2	MP:0020933
MousePheno	abnormal susceptibility to Ortervirales infection	APOBEC3B APOBEC3F	4.83e-04	20	23	2	MP:0020918
MousePheno	disorganized yolk sac vascular plexus	KAT7 F3	5.86e-04	22	23	2	MP:0001723
Domain	Glycogen_synth	GYS1 GYS2	2.01e-06	2	27	2	IPR008631
Domain	Glycogen_syn	GYS1 GYS2	2.01e-06	2	27	2	PF05693
Domain	APOBEC_N	APOBEC3B APOBEC3F	1.32e-04	12	27	2	PF08210
Domain	APOBEC_N	APOBEC3B APOBEC3F	1.32e-04	12	27	2	IPR013158
Domain	APOBEC/CMP_deaminase_Zn-bd	APOBEC3B APOBEC3F	1.81e-04	14	27	2	IPR016192
Domain	CYT_DCMP_DEAMINASES_2	APOBEC3B APOBEC3F	2.09e-04	15	27	2	PS51747
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3B APOBEC3F	2.70e-04	17	27	2	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3B APOBEC3F	2.70e-04	17	27	2	IPR002125
Domain	Cytidine_deaminase-like	APOBEC3B APOBEC3F	2.70e-04	17	27	2	IPR016193
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS	GYS1 GYS2	3.80e-05	6	23	2	M47620
Pathway	REACTOME_MRNA_EDITING_C_TO_U_CONVERSION	APOBEC3B APOBEC3F	5.32e-05	7	23	2	MM15412
Pathway	REACTOME_MRNA_EDITING	APOBEC3B APOBEC3F	9.10e-05	9	23	2	MM15445
Pathway	WP_DISORDERS_OF_GALACTOSE_METABOLISM	GYS1 GYS2	1.96e-04	13	23	2	M45545
Pathway	REACTOME_GLYCOGEN_SYNTHESIS	GYS1 GYS2	2.29e-04	14	23	2	M27247
Pathway	REACTOME_GLYCOGEN_STORAGE_DISEASES	GYS1 GYS2	3.01e-04	16	23	2	M27236
Pathway	REACTOME_METABOLISM_OF_RNA	PSMB8 NUP155 PRPF8 APOBEC3B XAB2 APOBEC3F	3.50e-04	612	23	6	MM15547
Pathway	REACTOME_GLYCOGEN_METABOLISM	GYS1 GYS2	7.47e-04	25	23	2	M27857
Pubmed	Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	32641479
Pubmed	APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	27602762
Pubmed	Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	286744
Pubmed	A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	22691411
Pubmed	Studies on the restriction of murine leukemia viruses by mouse APOBEC3.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	22666481
Pubmed	APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	24577894
Pubmed	Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	24725948
Pubmed	APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	16648136
Pubmed	Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	23533681
Pubmed	The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	20702647
Pubmed	Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	1541833
Pubmed	In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	27356895
Pubmed	IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	23315078
Pubmed	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	20980520
Pubmed	Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	25589647
Pubmed	Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	284359
Pubmed	Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	20617165
Pubmed	Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	31801862
Pubmed	Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	39208378
Pubmed	Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	31943071
Pubmed	Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	23671100
Pubmed	Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	31518043
Pubmed	Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	20566830
Pubmed	APOBEC-mediated viral restriction: not simply editing?	APOBEC3B APOBEC3F	1.74e-06	3	27	2	17303427
Pubmed	Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	7884913
Pubmed	N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	25505062
Pubmed	Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	31595054
Pubmed	APOBEC3 signature mutations in chronic lymphocytic leukemia.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	24840555
Pubmed	Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	17967065
Pubmed	Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	20335265
Pubmed	Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	29593034
Pubmed	Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	31830125
Pubmed	Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	9765497
Pubmed	Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	21998583
Pubmed	Biochemical and biological studies of mouse APOBEC3.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	24453360
Pubmed	Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	38115583
Pubmed	APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	23449789
Pubmed	Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	2157836
Pubmed	Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	35458563
Pubmed	Natural resistance to HIV infection: The Vif-APOBEC interaction.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	17067930
Pubmed	Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	22275865
Pubmed	APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	18434399
Pubmed	Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	19153238
Pubmed	Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	18772436
Pubmed	Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	293683
Pubmed	Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	19150103
Pubmed	Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	18786991
Pubmed	Initial sequencing and comparative analysis of the mouse genome.	APOBEC3B APOBEC3F	1.74e-06	3	27	2	12466850
Pubmed	Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	24821801
Pubmed	Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	20363737
Pubmed	Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	18983852
Pubmed	Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	29343743
Pubmed	APOBEC3 regulates keratinocyte differentiation and expression of Notch3.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	31400166
Pubmed	APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	15674295
Pubmed	Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	21873525
Pubmed	Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	23725696
Pubmed	APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	21985787
Pubmed	Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population.	DPP4 TMPRSS6	3.48e-06	4	27	2	38309700
Pubmed	APOBEC3A functions as a restriction factor of human papillomavirus.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	25355878
Pubmed	Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	26253512
Pubmed	APOBEC3 enzymes restrict marginal zone B cells.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	25501566
Pubmed	Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	18702815
Pubmed	HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	20538015
Pubmed	Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	17020885
Pubmed	Persistence of viremia and production of neutralizing antibodies differentially regulated by polymorphic APOBEC3 and BAFF-R loci in friend virus-infected mice.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	20375169
Pubmed	APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	21147467
Pubmed	Mice deficient in APOBEC2 and APOBEC3.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	16055735
Pubmed	The incorporation of APOBEC3 proteins into murine leukemia viruses.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	18572219
Pubmed	The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	38049664
Pubmed	Restriction of foamy viruses by APOBEC cytidine deaminases.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	16378963
Pubmed	Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	26846717
Pubmed	Vaccinia virus replication is not affected by APOBEC3 family members.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	17052331
Pubmed	Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	28415995
Pubmed	Immunity to retroviral infection: the Friend virus model.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	9223268
Pubmed	Species-specific restriction of apobec3-mediated hypermutation.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	18032489
Pubmed	Multifaceted HIV-1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	32893454
Pubmed	Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	25303118
Pubmed	APOBEC3 inhibits mouse mammary tumour virus replication in vivo.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	17259974
Pubmed	HIV restriction by APOBEC3 in humanized mice.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	23555255
Pubmed	The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	36480186
Pubmed	Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.	APOBEC3B APOBEC3F	3.48e-06	4	27	2	15269786
Pubmed	APOBEC3 inhibits DEAD-END function to regulate microRNA activity.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	23890083
Pubmed	Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	21659520
Pubmed	HIV-1 Vif, APOBEC, and intrinsic immunity.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	18577210
Pubmed	Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	24851906
Pubmed	IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	22972924
Pubmed	The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	18304004
Pubmed	Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism.	APOBEC3B APOBEC3F	5.80e-06	5	27	2	17977970
Pubmed	Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1).	APOBEC3B APOBEC3F	5.80e-06	5	27	2	18509452
Pubmed	SERINC5 Potently Restricts Retrovirus Infection In Vivo.	APOBEC3B APOBEC3F	8.69e-06	6	27	2	32665269
Pubmed	Retroelements versus APOBEC3 family members: No great escape from the magnificent seven.	APOBEC3B APOBEC3F	8.69e-06	6	27	2	22912627
Pubmed	APOBEC3 versus Retroviruses, Immunity versus Invasion: Clash of the Titans.	APOBEC3B APOBEC3F	8.69e-06	6	27	2	22720156
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	GYS1 GYS2	8.69e-06	6	27	2	14680475
Pubmed	APOBEC3 proteins mediate the clearance of foreign DNA from human cells.	APOBEC3B APOBEC3F	1.22e-05	7	27	2	20062055
Pubmed	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.	APOBEC3B APOBEC3F	1.22e-05	7	27	2	11863358
Pubmed	APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.	APOBEC3B APOBEC3F	1.22e-05	7	27	2	16527742
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	GYS1 GYS2	1.22e-05	7	27	2	18165236
Pubmed	DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.	APOBEC3B APOBEC3F	1.22e-05	7	27	2	29871919
Pubmed	Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.	APOBEC3B APOBEC3F	1.22e-05	7	27	2	21835787
Pubmed	APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.	APOBEC3B APOBEC3F	1.62e-05	8	27	2	24227842
Cytoband	Ensembl 112 genes in cytogenetic band chr22q13	KDELR3 APOBEC3B APOBEC3F	9.47e-04	330	27	3	chr22q13
Cytoband	22q13.1	KDELR3 APOBEC3F	1.15e-03	85	27	2	22q13.1
Cytoband	17p13.3	PRPF8 SGSM2	1.24e-03	88	27	2	17p13.3
GeneFamily	Glycosyl transferases group 1 domain containing	GYS1 GYS2	6.92e-05	10	23	2	427
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3B APOBEC3F	1.01e-04	12	23	2	406
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NFASC FLT4	1.76e-02	161	23	2	593
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 STEAP2 GYS2	9.44e-05	147	27	3	5e6dd2ddc67b3722f6528e7277cbc7f296098687
ToppCell	Leuk-UTI-Lymphocyte-T_NK-MAIT\|Leuk-UTI / Disease, Lineage and Cell Type	DPP4 FLT4 XKR6	1.06e-04	153	27	3	ac3a1d1b5bf6009df818fd757dad7382d95c60dc
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FLT4 TMPRSS6 GYS2	1.08e-04	154	27	3	928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCell	367C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP4 FLT4 APOBEC3B	1.24e-04	161	27	3	c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell	367C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP4 FLT4 APOBEC3B	1.24e-04	161	27	3	9864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC F3 MMP28	1.35e-04	166	27	3	dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC DPP4 F3	1.40e-04	168	27	3	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC DPP4 F3	1.40e-04	168	27	3	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFASC NBEAL2 TMPRSS6	1.40e-04	168	27	3	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 NBEAL2	1.50e-04	172	27	3	6ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 KCNU1 TMPRSS6	1.55e-04	174	27	3	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFASC NBEAL2 TMPRSS6	1.61e-04	176	27	3	71f96cace3f20fbef975037f4deff9b82b0282a1
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGIF2 XKR6 NBEAL2	1.66e-04	178	27	3	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGIF2 XKR6 NBEAL2	1.66e-04	178	27	3	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGIF2 XKR6 NBEAL2	1.66e-04	178	27	3	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFASC F3 GYS2	1.69e-04	179	27	3	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WDR91 DIS3L NBEAL2	1.74e-04	181	27	3	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MMP28 NBEAL2 WWC1	1.80e-04	183	27	3	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	1.80e-04	183	27	3	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC FLT4 F3	1.80e-04	183	27	3	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC FLT4 F3	1.80e-04	183	27	3	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	1.80e-04	183	27	3	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	F3 NBEAL2 WWC1	1.83e-04	184	27	3	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC FLT4 F3	1.83e-04	184	27	3	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	F3 NBEAL2 WWC1	1.83e-04	184	27	3	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	DPP4 F3 WWC1	1.86e-04	185	27	3	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	F3 MMP28 WWC1	1.86e-04	185	27	3	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	DPP4 F3 WWC1	1.89e-04	186	27	3	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MMP28 NBEAL2 WWC1	1.92e-04	187	27	3	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	droplet-Thymus-nan-18m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F3 TMPRSS6 WWC1	1.92e-04	187	27	3	ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	KDELR3 F3 XAB2	1.92e-04	187	27	3	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	1.95e-04	188	27	3	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	F3 NBEAL2 WWC1	1.95e-04	188	27	3	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	1.95e-04	188	27	3	b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DPP4 FLT4 MMP28	1.95e-04	188	27	3	986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	1.98e-04	189	27	3	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	1.98e-04	189	27	3	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DPP4 F3 WWC1	1.98e-04	189	27	3	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	1.98e-04	189	27	3	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.01e-04	190	27	3	97772e69e6f51ebffbb5433ca7b40f1048723220
ToppCell	droplet-Lung-nan-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.01e-04	190	27	3	72c2b824acdc43139e6635785df3ed3feb58ec46
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP4 MMP28 WWC1	2.01e-04	190	27	3	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.04e-04	191	27	3	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	2.04e-04	191	27	3	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	DPP4 MMP28 WWC1	2.04e-04	191	27	3	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	facs-BAT-Fat-24m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	24d682e3247a73d349e7776b9e564b6b57f4cb13
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	0b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	61c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 F3 TMPRSS6	2.08e-04	192	27	3	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 NBEAL2	2.08e-04	192	27	3	44cb225392c8d07150955ecf203fbdf6021c9790
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPP4 F3 NBEAL2	2.08e-04	192	27	3	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.11e-04	193	27	3	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPP4 TMPRSS6 WWC1	2.11e-04	193	27	3	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	2.11e-04	193	27	3	2661ad9107ed9231e4afea4442a79051139a31df
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 STEAP2 TMPRSS6	2.11e-04	193	27	3	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 STEAP2 TMPRSS6	2.11e-04	193	27	3	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPP4 TMPRSS6 WWC1	2.11e-04	193	27	3	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 STEAP2 TMPRSS6	2.11e-04	193	27	3	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.11e-04	193	27	3	fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	2.14e-04	194	27	3	0e315c63407fa00643722a7d6138b1502f79b10d
ToppCell	PCW_05-06-Endothelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	2.14e-04	194	27	3	00291c62795a55a7e63b1db10c139d6a3298e55e
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	2.14e-04	194	27	3	588c45dafa00547b2506e298a2434b1b5e15560d
ToppCell	PCW_05-06-Endothelial-Endothelial_immature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	2.14e-04	194	27	3	9bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KDELR3 F3 TMPRSS6	2.14e-04	194	27	3	c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCell	PND01-Epithelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP4 F3 WWC1	2.14e-04	194	27	3	d21db5e942966ed44bc78ff50130a201fc627074
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 F3 TMPRSS6	2.14e-04	194	27	3	c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP4 F3 WWC1	2.17e-04	195	27	3	43164511f32e4591cb5399182fbac0b911716233
ToppCell	PND01-Epithelial-Epithelial_Alveolar\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP4 F3 WWC1	2.17e-04	195	27	3	9337111d75a487abc02969337718c30b1fe81379
ToppCell	PCW_07-8.5-Endothelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	2.17e-04	195	27	3	f2cc94d5e1652203ca38bea57f37d3deec73ef04
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PSMB8 FLT4 MMP28	2.17e-04	195	27	3	c7abcb674e4a25a5354c4947fffd0d17bc8c1fab
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	DPP4 F3 WWC1	2.20e-04	196	27	3	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	PSB-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KDELR3 STEAP2 F3	2.27e-04	198	27	3	e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F3 MMP28 WWC1	2.31e-04	199	27	3	456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell	343B-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PSMB8 STEAP2 F3	2.31e-04	199	27	3	08c7e631b2e203dd7dcb75a7f9377d292bc5a0fd
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F3 MMP28 WWC1	2.31e-04	199	27	3	c11365653c69a5dfb37946231f8af05149a61a71
ToppCell	343B-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PSMB8 STEAP2 F3	2.31e-04	199	27	3	4338bf6cafc26c5d6497955d91914f84bacfacfa
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F3 MMP28 WWC1	2.31e-04	199	27	3	5263338242f95c04690d0795749ccc20b0d19f7a
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	DPP4 F3 MMP28	2.31e-04	199	27	3	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	distal-Epithelial-Club-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F3 TMPRSS6 WWC1	2.31e-04	199	27	3	685cefbe6ff5db8b578e50b5849524ac2f347d0c
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DPP4 F3 WWC1	2.34e-04	200	27	3	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPP4 F3 WWC1	2.34e-04	200	27	3	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	NFASC XKR6 WWC1	2.34e-04	200	27	3	7bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DPP4 F3 MMP28	2.34e-04	200	27	3	cf1991853e10c562edae9a0d71a209f35b07db80
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DPP4 F3 WWC1	2.34e-04	200	27	3	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Parenchymal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F3 MMP28 WWC1	2.34e-04	200	27	3	4e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPP4 F3 MMP28	2.34e-04	200	27	3	7618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	PCNX4 GYS1 WWC1	2.34e-04	200	27	3	eac33be484dc443794e66e473f03e98406c2983e
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DPP4 F3 MMP28	2.34e-04	200	27	3	23b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F3 MMP28 WWC1	2.34e-04	200	27	3	b2d61bc3afac0d78aa30082760da5b1a15d1fad2
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-MAIT\|Leuk-UTI / Disease, condition lineage and cell class	DPP4 FLT4 XKR6	2.34e-04	200	27	3	7e0d0f051c197c2c70080f039e1c4dd68db8e74f
Drug	Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	WDR91 DPP4 F3 SGSM2 XAB2	3.11e-06	196	27	5	5830_DN
Drug	v 405	GYS1 GYS2	4.06e-06	3	27	2	CID003057126
Drug	nicotine iminium	GYS1 GYS2	4.06e-06	3	27	2	CID000000431
Drug	m-anisidine	GYS1 GYS2	1.35e-05	5	27	2	CID000010824
Drug	hexanediamine	GYS1 GYS2	2.03e-05	6	27	2	CID000134940
Drug	Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ala-Ala-Lys-Lys	GYS1 GYS2	2.03e-05	6	27	2	CID003277749
Drug	phenyl glucuronide	GYS1 GYS2	2.03e-05	6	27	2	CID000087235
Drug	AC1L196J	GYS1 GYS2	2.03e-05	6	27	2	CID000000415
Drug	BAY R3401	GYS1 GYS2	2.03e-05	6	27	2	CID009842599
Drug	5-chloro-indole-2-carboxylic acid	GYS1 GYS2	2.03e-05	6	27	2	CID000082693
Drug	NSC106398	GYS1 GYS2	2.83e-05	7	27	2	CID000086763
Drug	Chloropeptide	GYS1 GYS2	2.83e-05	7	27	2	CID000025565
Drug	C0761	APOBEC3B APOBEC3F	3.78e-05	8	27	2	CID006321196
Drug	N-cyclopropylammelide	APOBEC3B APOBEC3F	3.78e-05	8	27	2	CID000592814
Drug	gamma-glutamylhydroxamate	GYS1 GYS2	4.85e-05	9	27	2	CID000159636
Drug	alpha-chloroisocaproate	GYS1 GYS2	4.85e-05	9	27	2	CID000169071
Drug	H-47	GYS1 GYS2	6.06e-05	10	27	2	CID003083866
Drug	UDP-pyridoxal	GYS1 GYS2	6.06e-05	10	27	2	CID000126789
Drug	glycogen phosphorylase inhibitor	GYS1 GYS2	7.40e-05	11	27	2	CID010070301
Drug	AC1L1BIZ	GYS1 GYS2	7.40e-05	11	27	2	CID000001459
Drug	PMSA	DPP4 FLT4	7.40e-05	11	27	2	CID000125605
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A	FLT4 F3 NBEAL2 WWC1	7.85e-05	195	27	4	3278_UP
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	KDELR3 TGIF2 F3 WWC1	7.85e-05	195	27	4	6424_DN
Drug	Ofloxacin [82419-36-1]; Down 200; 11uM; HL60; HT_HG-U133A	WDR91 F3 NBEAL2 WWC1	7.85e-05	195	27	4	2340_DN
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A	WDR91 KDELR3 F3 XAB2	8.00e-05	196	27	4	2648_DN
Drug	Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	WDR91 F3 NBEAL2 GYS1	8.16e-05	197	27	4	3425_DN
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A	NFASC SGSM2 TMPRSS6 WWC1	8.16e-05	197	27	4	4226_UP
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A	KDELR3 TGIF2 PCNX4 APOBEC3B	8.32e-05	198	27	4	5515_DN
Drug	Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A	DPP4 F3 NBEAL2 XAB2	8.32e-05	198	27	4	2094_DN
Drug	Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A	WDR91 GYS1 XAB2 WWC1	8.65e-05	200	27	4	4783_DN
Drug	AC1LCVS1	GYS1 GYS2	8.87e-05	12	27	2	CID000656959
Drug	p-MeC	GYS1 GYS2	1.22e-04	14	27	2	CID000451929
Drug	thiadiazolidinone	GYS1 GYS2	1.22e-04	14	27	2	CID000443041
Drug	AC1NRAG8	GYS1 GYS2	1.22e-04	14	27	2	CID005287861
Drug	AD-5075	GYS1 GYS2	1.41e-04	15	27	2	CID000128440
Drug	cytidine diphosphate-glucose	GYS1 GYS2	1.41e-04	15	27	2	CID000000292
Drug	M 16209	GYS1 GYS2	1.41e-04	15	27	2	CID000164260
Drug	1m0q	FLT4 GYS1 GYS2	1.43e-04	86	27	3	CID006323299
Drug	F-6b	GYS1 GYS2	1.61e-04	16	27	2	CID000004288
Drug	Sodium thioglucse	GYS1 GYS2	1.61e-04	16	27	2	CID000151466
Drug	BM 17.0744	GYS1 GYS2	1.61e-04	16	27	2	CID009929731
Drug	butylethanolamine	GYS1 GYS2	1.61e-04	16	27	2	CID000249006
Drug	mannosylamine	GYS1 GYS2	1.82e-04	17	27	2	CID000192844
Drug	proglycosyn	GYS1 GYS2	1.82e-04	17	27	2	CID000147052
Drug	JTT-501	GYS1 GYS2	1.82e-04	17	27	2	CID000154000
Drug	AC1L3X9U	DPP4 F3	2.05e-04	18	27	2	CID000096811
Drug	1-GlcNAc	GYS1 GYS2	2.05e-04	18	27	2	CID000151446
Drug	sucrose-6-phosphate	GYS1 GYS2	2.05e-04	18	27	2	CID000644101
Drug	N-methylcarbamate	GYS1 GYS2	2.29e-04	19	27	2	CID000030536
Drug	1-azakenpaullone	GYS1 GYS2	2.29e-04	19	27	2	CID006538897
Drug	phorbol-12,13-dibenzoate	GYS1 GYS2	2.54e-04	20	27	2	CID000072294
Drug	magnesium acetate tetrahydrate	GYS1 GYS2	2.54e-04	20	27	2	CID000134717
Drug	N-[4,5,7-Tricarboxyheptanoyl]-L-Gamma-Glutamyl-N-{2-[4-({5-[(Formylamino)methyl]-3-Furyl}methoxy)phenyl]ethyl}-D-Glutamine	GYS1 GYS2	3.08e-04	22	27	2	CID011840961
Drug	emiglitate	GYS1 GYS2	3.08e-04	22	27	2	CID000072004
Drug	HOBt	FLT4 F3	3.08e-04	22	27	2	CID000075771
Drug	maltosaccharide	GYS1 GYS2	3.08e-04	22	27	2	CID005461034
Drug	AC1L9IMU	GYS1 GYS2	3.37e-04	23	27	2	CID000445825
Drug	1nfx	GYS1 GYS2	3.68e-04	24	27	2	CID000447361
Drug	AC1LARMV	GYS1 GYS2	4.32e-04	26	27	2	CID000493817
Drug	bisindolylmaleimide V	GYS1 GYS2	5.02e-04	28	27	2	CID000002400
Drug	1-o-phosphonohex-2-ulose	GYS1 GYS2	5.39e-04	29	27	2	CID000000481
Drug	cantharidic acid	GYS1 GYS2	5.39e-04	29	27	2	CID000002544
Drug	AC1L3NLD	GYS1 GYS2	5.39e-04	29	27	2	CID000092184
Drug	N,N'-disalicylidene-1,3-diaminopropane	GYS1 GYS2	5.77e-04	30	27	2	CID005373003
Drug	MCC-555	GYS1 GYS2	6.17e-04	31	27	2	CID000204109
Drug	AP2PL	GYS1 GYS2	6.17e-04	31	27	2	CID000121867
Drug	1 sulfonylurea	DPP4 GYS1 GYS2	6.35e-04	143	27	3	CID011819083
Drug	M3/M4	GYS1 GYS2	6.57e-04	32	27	2	CID000486507
Drug	inhibitor 1	F3 GYS1 GYS2	6.75e-04	146	27	3	CID011530041
Drug	deoxythymidine diphosphate-glucose	GYS1 GYS2	6.99e-04	33	27	2	CID000000684
Drug	aldohexose 6-phosphate	GYS1 GYS2	6.99e-04	33	27	2	CID000085186
Drug	Lyndiol	GYS1 GYS2	7.42e-04	34	27	2	CID000082149
Drug	2-deoxy-D-arabino-hexose 6-phosphate	GYS1 GYS2	7.42e-04	34	27	2	CID000108108
Drug	glutathione sulfinate	GYS1 GYS2	8.32e-04	36	27	2	CID005326960
Drug	LiBr	GYS1 GYS2	8.32e-04	36	27	2	CID000082050
Drug	I TU	GYS1 GYS2	8.79e-04	37	27	2	CID000001830
Drug	1f4x	GYS1 GYS2	9.27e-04	38	27	2	CID000445507
Drug	SB415286	GYS1 GYS2	9.77e-04	39	27	2	CID004210951
Drug	glibenclamide	DPP4 FLT4 GYS1 GYS2	1.01e-03	382	27	4	CID000003488
Drug	2bub	DPP4 F3	1.03e-03	40	27	2	CID005494422
Drug	SB216763	GYS1 GYS2	1.03e-03	40	27	2	CID000176158
Disease	Lafora disease (implicated_via_orthology)	GYS1 GYS2	4.83e-06	4	27	2	DOID:3534 (implicated_via_orthology)
Disease	iron biomarker measurement, serum iron measurement	F3 TMPRSS6	5.29e-05	12	27	2	EFO_0004461, EFO_0006332
Disease	iron biomarker measurement, transferrin saturation measurement	F3 TMPRSS6	7.29e-05	14	27	2	EFO_0004461, EFO_0006333
Disease	transferrin saturation measurement	F3 TMPRSS6	9.60e-05	16	27	2	EFO_0006333
Disease	serum hepcidin measurement	F3 TMPRSS6	1.22e-04	18	27	2	EFO_0004504
Disease	iron biomarker measurement, transferrin measurement	F3 TMPRSS6	1.52e-04	20	27	2	EFO_0004461, EFO_0006341
Disease	Glycogen Storage Disease	GYS1 GYS2	2.79e-04	27	27	2	C0017919
Disease	iron biomarker measurement	F3 TMPRSS6	8.86e-04	48	27	2	EFO_0004461
Disease	lifestyle measurement	XKR6 SGSM2 WWC1	1.27e-03	235	27	3	EFO_0010724
Disease	total iron binding capacity	F3 TMPRSS6	2.32e-03	78	27	2	EFO_0006334
Disease	hippocampal volume	DPP4 XKR6 WWC1	2.47e-03	297	27	3	EFO_0005035
Disease	serum iron measurement	F3 TMPRSS6	2.81e-03	86	27	2	EFO_0006332

Protein segments in the cluster

Peptide	Gene	Start	Entry
ARLYYYWERDYRRAL	APOBEC3B	121	Q9UH17
RLSDLLDWRYLGRYY	GYS2	591	P54840
YWERLLAKECRLYYL	PSMB8	126	P28062
LISYRSYWKEVLLRY	KAT7	516	O95251
RSTRWYNLLSYKYLK	WWC1	776	Q8IX03
RELIKYLEEYERDWY	PCNX4	1046	Q63HM2
GLYRALYLANWIRRY	KDELR3	156	O43731
KLYSLRWISDHEYLY	DPP4	56	P27487
YYLKSNWLGLRFLRA	KCNU1	186	A8MYU2
RYMDLLWRYYEKNRS	NUP155	1076	O75694
YRAYYWRESSLLKNL	NFASC	861	O94856
RLYYYWERDYRRALC	APOBEC3F	121	Q8IUX4
WYGRTIIRSAYKLFY	DIS3L	576	Q8TF46
WIGYLELRRYTYLAK	KRBOX1	91	C9JBD0
RLSDLLDWKYLGRYY	GYS1	591	P13807
LDWKYLGRYYMSARH	GYS1	596	P13807
YYKRLGRDALLSWDD	MMP28	261	Q9H239
CSYKLWYRYLKARRA	XAB2	66	Q9HCS7
RLYELWLLYYAQKDL	NBEAL2	6	Q6ZNJ1
CYRWFLLDFKRELLY	SGSM2	911	O43147
LIYGWKRAFEEEYYR	STEAP2	411	Q8NFT2
KILRDWLYLHRYNAY	TGIF2	31	Q9GZN2
YLDQYLWYEADKRRL	PRPF8	921	Q6P2Q9
DLWLALDYYRKGDYV	XKR6	146	Q5GH73
DSYKYEHLRWYRLNL	FLT4	581	P35916
RDVFGKDLIYTLYYW	F3	176	P13726
YDLAALRDYWSYLER	WDR91	56	A4D1P6
LWFDAYALRRQKYDL	TMPRSS6	381	Q8IU80