Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	kinociliary basal body	MKKS CDC14A	7.91e-05	3	108	2	GO:1902636
GeneOntologyCellularComponent	actin cytoskeleton	ARHGEF5 SIPA1L3 SYNPO2L SPPL2B ASAP1 KPTN AKAP13 NEURL1B PLEKHH2 JAM3 ARHGAP33	1.95e-04	576	108	11	GO:0015629
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CRYBG2 TBC1D9B SIPA1L3 LAMB2 AMBRA1 SPIRE1 SPPL2B WDR59 ADCY9 LATS2 GAREM2 ZNRF3 AKAP13 MED13 ARHGAP33 CD276 BAHCC1	9.54e-08	1105	112	17	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 ARHGEF5 SIPA1L3 MPDZ SPIRE1 RFX7 CDC14A WDR59 NARS2 FNIP1 AKAP13 FAM53B DEPDC1B GAB1 WDR62	1.20e-07	861	112	15	36931259
Pubmed	Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.	MUC5AC MUC6	1.03e-05	2	112	2	28321513
Pubmed	Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs.	MUC5AC MUC6	1.03e-05	2	112	2	9422745
Pubmed	Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.	MUC5AC MUC6	1.03e-05	2	112	2	12360467
Pubmed	Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes.	CASR GABBR1	1.03e-05	2	112	2	17615148
Pubmed	Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.	MUC5AC MUC6	1.03e-05	2	112	2	11988092
Pubmed	DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.	DLG5 SAV1 LATS2	1.15e-05	14	112	3	28087714
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KCNH7 EPX ASAP1 CDKL5 GTF3A SLC22A3 GABBR1 MOS	1.19e-05	329	112	8	17474147
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	ZNF219 VPS72 RBBP5 MSH6 MTA3 MED13	1.76e-05	167	112	6	20362541
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	ARHGEF5 SIPA1L3 SAV1 SPIRE1 FAM53B	2.06e-05	102	112	5	15778465
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DLG5 PCLO SIPA1L3 ADCY9 MED13	2.37e-05	105	112	5	9628581
Pubmed	Mucin expression in reactive gastropathy: an immunohistochemical analysis.	MUC5AC MUC6	3.08e-05	3	112	2	17227128
Pubmed	Mucin phenotype expression of gastric neuroendocrine neoplasms: analysis of histopathology and carcinogenesis.	MUC5AC MUC6	3.08e-05	3	112	2	23828549
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC5AC MUC6	3.08e-05	3	112	2	18825309
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC5AC MUC6	3.08e-05	3	112	2	18300795
Pubmed	A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer.	MUC5AC MUC6	3.08e-05	3	112	2	19924550
Pubmed	Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons.	CASR GABBR1	3.08e-05	3	112	2	17591780
Pubmed	Differential screening identifies genetic markers of monocyte to macrophage maturation.	WARS1 CDKL5	3.08e-05	3	112	2	8864140
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ABCC1 CEP85 SIPA1L3 ZNF280C EYA2 CDC14A MTMR10 ADCY9 ASAP1 MSH6 PPP2R5E FBXO33 GAB1	3.42e-05	1049	112	13	27880917
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLG5 ZNF280C PHRF1 AMBRA1 SPIRE1 ADCY9 MTA3 FAM53B MED13	5.59e-05	529	112	9	14621295
Pubmed	Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas.	SFMBT2 GAB1	6.14e-05	4	112	2	32358519
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC5AC MUC6	6.14e-05	4	112	2	33154304
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC5AC MUC6	6.14e-05	4	112	2	24901817
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC5AC MUC6	6.14e-05	4	112	2	36367122
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5AC MUC6	6.14e-05	4	112	2	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5AC MUC6	6.14e-05	4	112	2	14984930
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5AC MUC6	6.14e-05	4	112	2	29869461
Pubmed	Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?	MUC5AC MUC6	6.14e-05	4	112	2	20929551
Pubmed	Prognostic significance of CDX2 and mucin expression in small intestinal adenocarcinoma.	MUC5AC MUC6	6.14e-05	4	112	2	24603585
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5AC MUC6	6.14e-05	4	112	2	23807779
Pubmed	MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.	MUC5AC MUC6	6.14e-05	4	112	2	27298226
Pubmed	NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway.	SAV1 LATS2	6.14e-05	4	112	2	25692647
Pubmed	Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.	MUC5AC MUC6	6.14e-05	4	112	2	17401217
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5AC MUC6	6.14e-05	4	112	2	12676567
Pubmed	Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.	MUC5AC MUC6	6.14e-05	4	112	2	25298197
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DLG5 SIPA1L3 MPDZ FNIP1 GAB1 WDR62	6.17e-05	209	112	6	36779422
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	ABCC1 PHRF1 AMBRA1 PWP2 TRMT61B ARHGAP33 CD276	6.40e-05	307	112	7	37499664
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPHB6 CEP85 WARS1 VPS72 SIPA1L3 SIM2 MTMR10 WDR59 NFE2L3 PPP2R5E GTF3A MTA3 PJA1 MED13	6.77e-05	1285	112	14	35914814
Pubmed	Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.	SAV1 MPDZ LATS2	8.01e-05	26	112	3	28720576
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC1 MTMR10 ADCY9 CDKL5 LATS2 DEPDC1B GAB1 JAM3 CD276	9.73e-05	569	112	9	30639242
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MUC5AC MUC6	1.02e-04	5	112	2	22261707
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC5AC MUC6	1.02e-04	5	112	2	16475027
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	WARS1 AMBRA1 SPIRE1 FNIP1 AKAP13 WDR62	1.10e-04	232	112	6	25515538
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	ZNF219 VPS72 RBBP5 MSH6 MTA3	1.14e-04	146	112	5	23892456
Pubmed	Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.	SAV1 LATS2	1.53e-04	6	112	2	20303269
Pubmed	The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.	SAV1 LATS2	1.53e-04	6	112	2	15688006
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5AC MUC6	1.53e-04	6	112	2	19110483
Pubmed	Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins.	MUC5AC MUC6	1.53e-04	6	112	2	17982272
Pubmed	Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.	SAV1 LATS2	1.53e-04	6	112	2	30266805
Pubmed	Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.	WARS1 ZNRF3	1.53e-04	6	112	2	23670221
Pubmed	Hippo signaling impedes adult heart regeneration.	SAV1 LATS2	2.14e-04	7	112	2	24255096
Pubmed	Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.	SFMBT2 GAB1	2.14e-04	7	112	2	35483741
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF219 VPS72 PHRF1 AMBRA1 ADCY9 MSH6 PPP2R5E MTA3 ZNRF3 ARHGAP33 WDR62 BAHCC1	2.61e-04	1116	112	12	31753913
Pubmed	Pervasive translational regulation of the cell signalling circuitry underlies mammalian development.	SAV1 LATS2	2.84e-04	8	112	2	28195124
Pubmed	Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.	KEL MSLN	2.84e-04	8	112	2	25798939
Pubmed	Hippo pathway-dependent and -independent roles of RASSF6.	SAV1 LATS2	2.84e-04	8	112	2	19797269
Pubmed	AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation.	SAV1 LATS2	2.84e-04	8	112	2	34404733
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	RBBP5 PCLO BCORL1 PPOX MSH6 PPP2R5E MTA3	3.06e-04	396	112	7	26687479
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	ABCC1 TRAF1 RBBP5 PJA1 TRMT61B TMCO1	3.20e-04	283	112	6	21903422
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DLG5 VPS72 RBBP5 SIPA1L3 PHRF1 MPDZ LAMB2 SPIRE1 MSH6 PPP2R5E MTA3 PWP2 TMCO1 MED13	3.29e-04	1497	112	14	31527615
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	PRAMEF20 ZNF280C SKIDA1 ZC3H12B CDKL5 RPGR KLHDC7A PJA1 MSLN	3.41e-04	674	112	9	37196079
Pubmed	Superresolution imaging of chemical synapses in the brain.	PCLO GABBR1	3.65e-04	9	112	2	21144999
Pubmed	Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.	SAV1 LATS2	5.55e-04	11	112	2	28486106
Pubmed	WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.	SAV1 LATS2	6.64e-04	12	112	2	35429439
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	RBBP5 ARHGEF5 KPRP MPDZ WDR59 ASAP1 PPP2R5E AKAP13 DEPDC1B ARHGAP33	7.70e-04	916	112	10	32203420
Pubmed	Structure of the nutrient-sensing hub GATOR2.	WDR59 KPTN	7.83e-04	13	112	2	35831510
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MKKS SAV1 AMBRA1 WDR59 MSH6 PJA1 TRMT61B WDR62	7.90e-04	606	112	8	36538041
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	PCLO LAMB2	9.12e-04	14	112	2	21228161
Pubmed	Quantitative trait loci for steady-state platelet count in mice.	EPX TMCO1	1.05e-03	15	112	2	15520881
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	EPHB6 PCLO PHRF1 LAMB2 MSH6 ZNF611 FNIP1	1.15e-03	496	112	7	31343991
Pubmed	A crucial role of WW45 in developing epithelial tissues in the mouse.	SAV1 LATS2	1.20e-03	16	112	2	18369314
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CEP85 RBBP5 ARHGEF5 MPDZ AMBRA1 AKAP13 TMCO1 CMTR2	1.24e-03	650	112	8	38777146
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	MTMR10 ADCY9 LATS2 DEPDC1B GAB1 JAM3	1.42e-03	377	112	6	38117590
Pubmed	Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications.	AMBRA1 SFMBT2 GAB1	1.46e-03	69	112	3	34941261
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5AC MUC6	1.52e-03	18	112	2	18834073
Pubmed	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.	WDR59 KPTN	1.88e-03	20	112	2	28199306
Pubmed	Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.	CDKL5 WDR62	1.88e-03	20	112	2	36551904
Pubmed	Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.	SPIRE1 ZNRF3 CACNA1I	1.93e-03	76	112	3	10574461
Pubmed	Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.	ABCC1 SLC22A3	2.07e-03	21	112	2	23137377
Pubmed	Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.	SAV1 LATS2	2.28e-03	22	112	2	21512031
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PCLO SIPA1L3 SKIDA1 EPX SFMBT2 NARS2 NFE2L3 LATS2 PWP2 TMCO1 MED13 BAHCC1	2.39e-03	1442	112	12	35575683
Pubmed	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	NFE2L3 ZNRF3	2.71e-03	24	112	2	20935629
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARHGEF5 ASAP1 UBQLN3 AKAP13 GAB1 SLC35A5	2.74e-03	430	112	6	35044719
Pubmed	Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.	MKKS ARMS2 RPGR	2.83e-03	87	112	3	20801516
Pubmed	The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.	MPDZ LATS2	2.94e-03	25	112	2	21145499
Pubmed	Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.	MUC5AC MUC6	2.94e-03	25	112	2	34391772
Pubmed	Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.	SAV1 LATS2	2.94e-03	25	112	2	19786569
Pubmed	Network organization of the human autophagy system.	WARS1 SAV1 AMBRA1 FNIP1 TRMT61B WDR62	2.97e-03	437	112	6	20562859
Pubmed	Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.	WARS1 NARS2 PPOX JAM3	3.14e-03	186	112	4	31540324
Pubmed	Identification of genes controlled by LMX1B in E13.5 mouse limbs.	SIM2 PANX3	3.18e-03	26	112	2	20589901
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	MKKS RFX7 SPPL2B LATS2 CD276	3.18e-03	306	112	5	18973680
Pubmed	An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.	ZNF219 MSH6 MTA3	3.21e-03	91	112	3	20362542
Cytoband	11p15.5	PHRF1 SIRT3 MUC5AC MUC6	2.08e-04	118	112	4	11p15.5
Cytoband	2p21	STPG4 MTA3 PLEKHH2	4.59e-04	61	112	3	2p21
Cytoband	Ensembl 112 genes in cytogenetic band chr2p21	STPG4 MTA3 PLEKHH2	1.01e-03	80	112	3	chr2p21
Cytoband	3p21	LAMB2 CCRL2	2.96e-03	33	112	2	3p21
GeneFamily	PDZ domain containing	DLG5 PCLO SIPA1L3 SYNPO2L MPDZ	5.07e-04	152	78	5	1220
Coexpression	GSE11386_NAIVE_VS_MEMORY_BCELL_DN	TRAF1 RFX7 SFMBT2 ASAP1 AKAP13 FAM53B GABBR1	4.79e-06	158	110	7	M372
Coexpression	GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN	CEP85 BCORL1 SFMBT2 ASAP1 LATS2 FBXO33 MED13	2.15e-05	199	110	7	M7976
Coexpression	GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP	EPHB6 SAV1 SFMBT2 ASAP1 LATS2 FNIP1 DNAJB5	2.22e-05	200	110	7	M7159
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP85 ZNF280C MPDZ NARS2 BCL6B FAM53B	3.59e-06	163	112	6	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WARS1 CNTNAP3 LAMB2 ASAP1 BCL6B RPGR	6.77e-06	182	112	6	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WARS1 CNTNAP3 LAMB2 ASAP1 BCL6B RPGR	7.20e-06	184	112	6	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 LAG3 EYA2 EPX SLC22A3 MUC6	7.43e-06	185	112	6	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 CEP85 CNTNAP3 PITPNM1 NEURL1B WDR62	9.74e-06	194	112	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	SPATA6L NEXMIF SPIRE1 CASR SIM2 PLEKHH2	1.03e-05	196	112	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
Disease	lymphocyte percentage of leukocytes	TRAF1 FAM220A CCRL2 EPX RFX7 NARS2 SIRT3 ADCY9 ZNRF3 FAM53B NEURL1B	3.65e-05	665	109	11	EFO_0007993
Disease	mucinous adenocarcinoma (is_marker_for)	MUC5AC MUC6	1.34e-04	5	109	2	DOID:3030 (is_marker_for)
Disease	serum gamma-glutamyl transferase measurement	DLG5 SIPA1L3 LAG3 GFRA4 NFE2L3 AKAP13 FAM53B KLHDC7A MUC6 MED13 CD276 BAHCC1	1.45e-04	914	109	12	EFO_0004532
Disease	intellectual disability (is_implicated_in)	CASR CDKL5 WDR62	1.85e-04	30	109	3	DOID:1059 (is_implicated_in)
Disease	common bile duct neoplasm (is_marker_for)	MUC5AC MSLN	3.73e-04	8	109	2	DOID:4608 (is_marker_for)
Disease	glucose measurement	WARS1 EPX CDC14A ADCY9 CACNA1I PLEKHH2 CDHR4	5.38e-04	380	109	7	EFO_0004468
Disease	kidney cancer (implicated_via_orthology)	SAV1 LATS2	7.28e-04	11	109	2	DOID:263 (implicated_via_orthology)
Disease	Ciliopathies	MKKS TMEM67 DNAAF3 RPGR	7.53e-04	110	109	4	C4277690
Disease	Nephronophthisis	TMEM67 SLC41A1	1.03e-03	13	109	2	C0687120
Disease	gastric ulcer (implicated_via_orthology)	MUC5AC MUC6	1.20e-03	14	109	2	DOID:10808 (implicated_via_orthology)
Disease	Bardet-Biedl syndrome (is_implicated_in)	MKKS TMEM67	1.20e-03	14	109	2	DOID:1935 (is_implicated_in)
Disease	breast carcinoma	VPS72 ARHGEF5 MIER3 SKIDA1 LAMB2 CDC14A ADCY9 ZNRF3 KLHDC7A GAB1 BAHCC1	1.39e-03	1019	109	11	EFO_0000305
Disease	protein-glutamine gamma-glutamyltransferase e measurement	DLG5 NFE2L3 CD276	1.44e-03	60	109	3	EFO_0020690
Disease	plasma beta-amyloid 1-40 measurement	SAV1 DNAAF3	1.77e-03	17	109	2	EFO_0005659
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	RFX7 MED13	1.77e-03	17	109	2	DOID:0060307 (is_implicated_in)
Disease	Bardet-Biedl syndrome	MKKS TMEM67	1.99e-03	18	109	2	cv:C0752166
Disease	triglyceride measurement, body fat percentage	EYA2 SLC22A3	2.71e-03	21	109	2	EFO_0004530, EFO_0007800
Disease	psoriasis	KCNH7 VPS72 KPRP CASR AKAP13	3.49e-03	273	109	5	EFO_0000676

Protein segments in the cluster

Peptide	Gene	Start	Entry
CNIFRTLPPSDSNEF	PPP2R5E	121	Q16537
TRSCSQPIPECRFDS	BHLHB9	271	Q6PI77
CLPAFFSPAGTQRRF	ARMS2	76	P0C7Q2
PSRDALFNPSRAFAC	BAHCC1	1771	Q9P281
CAFSRTPFLPADETF	CCRL2	181	O00421
NPFDIFFASSRSTRP	DNAJB5	106	O75953
CDAPLASALPRSSFS	CNTNAP3	31	Q9BZ76
RQPRTSPSCAFRSDD	CDC14A	406	Q9UNH5
GDRFSNSSTAFRPLC	CASR	381	P41180
FPRRETSCAARAPET	ARHGEF5	541	Q12774
LFPAPTECFARVSCS	FAM220A	106	Q7Z4H9
IPASFSLSRVCFPAA	BCORL1	411	Q5H9F3
DCSPTHSPRVLFRSN	AKAP13	2396	Q12802
FRFITFVCPTSSDPL	CMTR2	666	Q8IYT2
LSAPSFCRQISPEEF	DEPDC1B	426	Q8WUY9
LRCSFSPEPGFSLAQ	CD276	266	Q5ZPR3
DSPRSTFLLAFSPDR	AMBRA1	51	Q9C0C7
FSPACAPRTFRVQED	CDHR4	441	A6H8M9
FTRPSFPSCNRNGKR	CIRBP-AS1	86	Q8TBR5
SFVTDPCSLNAFRRS	MUC6	1041	Q6W4X9
SFLRSTRRPFVPQSC	MKKS	511	Q9NPJ1
FEQRRFPTPPTSRCT	IL17REL	286	Q6ZVW7
FRPDCPVPSRTNSFN	LATS2	396	Q9NRM7
SSSFPFSPVGNLCRR	MTMR10	736	Q9NXD2
RSFSPSSQCPEFLDL	KCNH7	1101	Q9NS40
SPITRSFARDSSRFP	GAB1	551	Q13480
SPALSNRQRFPTFFR	GABBR1	271	Q9UBS5
SFLPAPDRLRASASC	FBXO33	81	Q7Z6M2
SAPPSKRQCRSLSFS	FAM53B	106	Q14153
RPFFRSSSLDISAQP	PCLO	2391	Q9Y6V0
REPSFNETFRFSLSP	PCLO	5076	Q9Y6V0
PCPLREDSFTRFSSQ	KPTN	11	Q9Y664
KNQRDCIPFFRSAPS	EPX	276	P11678
LCPNNTFRRDPTART	NFE2L3	321	Q9Y4A8
PQACPSASERSLSSF	DLG5	881	Q8TDM6
LSSPGFCNTFRPVDD	PHRF1	791	Q9P1Y6
CDSRRPFSARDNPHS	LAMB2	91	P55268
FSGPQACTRFFSRIT	MSLN	131	Q13421
ILNCSFSRPDRPASV	LAG3	186	P18627
SPRSVQCRAESFPNT	MUC5AC	1991	P98088
PTDSRANPRFRNSSF	JAM3	181	Q9BX67
TSDFFPRPLRSNTAC	MIER3	136	Q7Z3K6
LRRSVAPAAPTSCDF	MSH6	76	P52701
LTFGCFLSRARSPPQ	PLEKHH2	191	Q8IVE3
LSGDCDQRFRFPSPI	RBBP5	96	Q15291
GSPISCFSPSNFSIR	PANX3	61	Q96QZ0
RGLDFDPLTFRCSSP	ARHGAP33	736	O14559
RFSACPSKPAFFRNI	KCNA6	281	P17658
RARPLPGSEFFSCQN	BCL6B	291	Q8N143
PQTGARPSETFARFC	DNAAF3	441	Q8N9W5
RRRQTFVPSCAFSGP	GFRA4	96	Q9GZZ7
CRRPASSTAFPREES	DBX2	156	Q6ZNG2
QFCSPRRAFSEQGPL	FNIP1	211	Q8TF40
PIAFFCLRQTTSPRN	CACNA1I	56	Q9P0X4
PVISEPFRSRFSRCS	CEP85	36	Q6P2H3
PFRSRFSRCSSVADS	CEP85	41	Q6P2H3
DQAALPASFRPQSCR	CRYBG2	1376	Q8N1P7
FSSERNPCNSSVPRD	ADCY9	956	O60503
ERSPRPQSFCHSSSI	ASAP1	731	Q9ULH1
RSTLCFLADSVSPRF	KLHDC7A	731	Q5VTJ3
SCFPQYRSRTSFSPC	KPRP	216	Q5T749
SFFSSSCLPVSCRPQ	KRTAP26-1	101	Q6PEX3
NPITFEDRLCLPSSF	KRTAP27-1	26	Q3LI81
ARRSCPSSLQVTSFP	ECI2	11	O75521
PSTSRYFPSSCLDLN	CDKL5	511	O76039
SALSCADPLAAFPNR	SLC22A3	106	O75751
LRSEFSPSVDARPCS	MOS	11	P00540
LCFSSTGNFPLRRIS	TMEM67	196	Q5HYA8
NPCPESSASFLSRIT	ABCC1	206	P33527
SAPLRVSQLFSRSCP	EYA2	41	O00167
FARALDCSSSVRQPS	MTA3	206	Q9BTC8
FLPNSVFPRCSERNL	RPGR	441	Q92834
SLSLPFQCQGRFSTR	GAREM2	226	Q75VX8
PSSCGFQVARPRFSA	SYNPO2L	946	Q9H987
APSFSNSFPQIFRDR	WARS1	286	P23381
FPFPTRRASSLDSLA	SPATA6L	251	Q8N4H0
SRFRFTFPGCRALSP	TMCO1	26	Q9UM00
CLLRSVRFCSSAPFP	NARS2	6	Q96I59
NFFPSVFTTCPKRES	NEXMIF	336	Q5QGS0
TCPAVLRSFASFPET	EPHB6	231	O15197
FRRTSFCKPPSVQAQ	SKIDA1	466	Q1XH10
PALSRCFELTTFSFR	PRAMEF20	371	Q5VT98
SPCEVARFFLSTLPA	SIM2	471	Q14190
TCAFPSSTLPARRQH	SIPA1L3	1576	O60292
RQPRAAAPSFFFSSI	SIRT3	81	Q9NTG7
CTTFFSPDVNSRSAR	SLC41A1	396	Q8IVJ1
FSAFTQCRRPLPTST	MED13	1716	Q9UHV7
ASPASPLSSRQSFCA	TBC1D9B	431	Q66K14
RSSRPSFIKICFPFS	nan	41	Q8IZM0
RRASTAFCPPAASSE	PITPNM1	661	O00562
RRTDICLPDSSPNAF	SAV1	46	Q9H4B6
FAGNSRELSIRSCFP	PPOX	171	P50336
PSCSTSRERPFQAGE	TRMT61B	141	Q9BVS5
RSSTPAIFASDPATC	MPDZ	1606	O75970
FSPSNSCLLFRSECP	SLC35A5	186	Q9BS91
RTFTSPRPTQFSCVA	PWP2	451	Q15269
SVTSCFQSRVPRFLP	STPG4	191	Q8N801
FQSRVPRFLPSCSKT	STPG4	196	Q8N801
LPPSRQSSRSLEEFC	SPIRE1	536	Q08AE8
SRFSPECPNSSLLNL	TRBV4-1	81	A0A577
RLNSSPLALCDRPFS	SPPL2B	401	Q8TCT7
TPARLSQARFSACLP	NEURL1B	201	A8MQ27
AQEAPPFCFRNTSFS	SFMBT2	391	Q5VUG0
AFRPDLSSASFQRPQ	TRAF1	361	Q13077
VECRNPFAFTPISSS	RFX7	921	Q2KHR2
CRSPCLDRPSFSQSS	ZC3H12B	81	Q5HYM0
DANIPFPRTSGARFC	WDR59	531	Q6PJI9
SRFTHTFPPRATQCL	WDR62	1106	O43379
PFIYRSRSPCRASEA	ZNRF3	596	Q9ULT6
DAPSVSTFQRISCRP	ZNF611	186	Q8N823
LPRRFICSFPDCSAN	GTF3A	36	Q92664
IFRTASQRCRDPPSN	ZNF280C	86	Q8ND82
NPPARCSRTFITFSD	VPS72	256	Q15906
PAARCSASRADFLPQ	PJA1	186	Q8NG27
RSSCPAFLRYPTENS	UBQLN3	406	Q9H347
GLARPQAPSSSAFRC	ZNF219	151	Q9P2Y4
AAFPLPSRTSFNDSL	KEL	616	P23276