Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

HNF1A MEF2B ZNF628 SPI1 EGR4 NFE2L1 NPAS4 FOXJ1

5.00e-04560668GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

HNF1A MEF2B ZNF628 SPI1 EGR4 NFE2L1 NPAS4 FOXJ1

5.37e-04566668GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

HNF1A MEF2B ZNF142 WIZ ZNF628 SPI1 NFATC4 EGR4 NFE2L1 TAL1 NPAS4 SP140 FOXJ1

6.28e-0414126613GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

HNF1A MEF2B WIZ ZNF628 SPI1 NFATC4 EGR4 NFE2L1 TAL1 NPAS4 IKZF4 FOXJ1

6.95e-0412446612GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

HNF1A MEF2B WIZ ZNF628 SPI1 NFATC4 EGR4 NFE2L1 TAL1 NPAS4 IKZF4 FOXJ1

8.40e-0412716612GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

HNF1A MEF2B ZNF142 WIZ ZNF628 SPI1 NFATC4 EGR4 NFE2L1 TAL1 NPAS4 IKZF4 FOXJ1

8.53e-0414596613GO:0000977
GeneOntologyMolecularFunctionhistone deacetylase binding

MIER2 MEF2B SPI1 TAL1

1.43e-03147664GO:0042826
DomainAlpha_kinase

ALPK3 ALPK1

1.88e-046672PF02816
DomainALPHA_KINASE

ALPK3 ALPK1

1.88e-046672PS51158
DomainAlpha_kinase

ALPK3 ALPK1

1.88e-046672SM00811
DomainMHCK_EF2_kinase

ALPK3 ALPK1

1.88e-046672IPR004166
Pubmed

PU.1/Spi-1 binds to the human TAL-1 silencer to mediate its activity.

SPI1 TAL1

3.66e-06267216298389
Pubmed

Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene.

SPI1 TAL1

3.66e-06267217644741
Pubmed

Adult hematopoiesis is regulated by TIF1γ, a repressor of TAL1 and PU.1 transcriptional activity.

SPI1 TAL1

1.10e-05367221474105
Pubmed

Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.

SPI1 IKZF4

1.10e-05367217403896
Pubmed

A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.

SPI1 TAL1

2.19e-05467222357756
Pubmed

Autism-associated miR-873 regulates ARID1B, SHANK3 and NRXN2 involved in neurodevelopment.

NRXN2 SHANK3

2.19e-05467233262327
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NFE2L1 ARHGEF1 WDR81 PLEKHG2

2.26e-058567415449545
Pubmed

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.

SPI1 TAL1

3.64e-05567218805961
Pubmed

Profound regulation of Na/K pump activity by transient elevations of cytoplasmic calcium in murine cardiac myocytes.

ZDHHC5 PLD2

3.64e-05567227627745
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

URB1 EFS PCDHA11 TAL1 SHANK3 FOXJ1

4.21e-0532967617474147
Pubmed

Alpha-kinases: a new class of protein kinases with a novel catalytic domain.

ALPK3 ALPK1

5.46e-05667210021370
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HNF1A BRD2 GTF3C1 NFATC4 NFE2L1 NPAS4 IKZF4 MEX3C

6.48e-0570967822988430
Pubmed

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

SPI1 TAL1

1.30e-0496727624372
Pubmed

Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism.

EFS NFATC4 ITPRIP

1.58e-045467325464930
Pubmed

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP.

SPI1 TAL1

1.63e-041067223980096
Pubmed

Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage.

HNF1A SPI1

2.81e-041367211027604
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

CCDC184 CUEDC2 METRN EFS PPP1R3F PLPPR3 PTDSS2

3.87e-0469767728298427
Pubmed

A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.

SPI1 TAL1

4.31e-041667220647008
Pubmed

Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.

SPI1 TAL1

4.31e-041667215914564
Pubmed

Genome-wide association analysis of age-at-onset in Alzheimer's disease.

DCHS2 ALPK3

4.88e-041767222005931
Pubmed

Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences.

HNF1A TAL1

5.48e-04186721387105
Pubmed

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.

WIZ EGR4

6.12e-041967230385546
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

NIBAN1 WIZ GTF3C1 ARHGEF1 PRRC2A

7.46e-0437067522922362
Pubmed

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

SPI1 TAL1

8.24e-04226729811459
Pubmed

Vegf regulates embryonic erythroid development through Gata1 modulation.

SPI1 TAL1

9.82e-042467220554972
Pubmed

Lymphatic function is required prenatally for lung inflation at birth.

NAPSA FOXJ1

9.82e-042467224733830
Pubmed

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.

SPI1 TAL1

9.82e-042467223334579
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

MIER2 EFHC2 EFS TSPOAP1 SEZ6L2

1.08e-0340267524722188
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KIF26A PPP1R3F SHANK3 TECPR1

1.08e-0323367437704626
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HNF1A GTF3C1 SPI1 NFATC4 NFE2L1 TAL1 FOXJ1

1.48e-0387767720211142
Pubmed

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.

COL4A2 SHANK3

1.54e-033067220080650
CoexpressionGSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN

CUEDC2 ARHGEF1 ALPK3 SEZ6L2 MAGEF1 TECPR1

1.24e-05200676M6567
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO3A COL6A6 EFS PLD2 SP140

4.73e-061636752d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

NIBAN1 ITPRIP CPD ALPK1 SP140

6.68e-061756758020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NIBAN1 SPI1 CPD ALPK1 SP140

1.16e-05196675fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NIBAN1 SPI1 CPD ALPK1 SP140

1.16e-05196675526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 SPI1 R3HDM4 ITPRIP CPD

1.24e-05199675119807ea333d1dc7743c6b9f03a2c63e09e19541
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 SPI1 R3HDM4 ITPRIP CPD

1.24e-05199675691e04871cd6cac0ea5fca1b7fd6421df9315db6
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 SPI1 R3HDM4 CPD ALPK1

1.27e-052006756beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate|10w / Sample Type, Dataset, Time_group, and Cell type.

ALPK3 PTDSS2 PLCB3 ALPK1 MEX3C

1.27e-05200675e5a8647c47a49c8c90c78d681193946de103d8ff
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 SPI1 R3HDM4 CPD ALPK1

1.27e-05200675026495aa7f1e7528a01d9199475cfc393677fc60
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA MEF2B SPI1 SP140

7.53e-05149674a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA SPI1 EGR4 SP140

7.73e-051506743dc23a37dbeb7f9df93683702a7838f7cc3ec9cc
ToppCelldroplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIBAN1 SPI1 SEZ6L2 STK24

9.92e-051606740b8151037b28f52a21918856a1e9336e8d5edb90
ToppCelldroplet-Lung-nan-21m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIBAN1 SPI1 SEZ6L2 STK24

9.92e-051606744738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCellControl-Treg|World / Disease group and Cell class

NRXN2 EGR4 ALPK3 IKZF4

1.02e-04161674ead9f5a491321f9e307f7c97e47a4ca124f59bb6
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL4A2 TSPOAP1 KIF26A SHANK3

1.07e-04163674d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF26A SEZ6L2 TAL1 SHANK3

1.34e-0417367466488d01e03264fb193285470901c9c4182fbae8
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

DIPK1C PLPPR3 TAL1 SHANK3

1.37e-041746746d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCellfacs-Spleen-nan-24m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RABEP2 NAPSA SPI1 SP140

1.37e-04174674a0641908ab6feaca5cd07142d7429983a2f68668
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA MEF2B SPI1 TAL1

1.43e-04176674e29a13b8152ee84ca82fd1158d96d3f112e3cde3
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA MEF2B SPI1 TAL1

1.43e-0417667400510bf8ede0945dfcbd58cc8f34fddf914b6e49
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 NRXN2 COL6A6 ARMH4

1.46e-04177674cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 NRXN2 COL6A6 ARMH4

1.46e-04177674db222faaecbe5600da39277243c4e7e764eb63c9
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHC2 EGR4 SEZ6L2 NPAS4

1.49e-04178674d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA NIBAN1 SPI1 SP140

1.49e-04178674ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA NIBAN1 SPI1 SP140

1.49e-041786746c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA NIBAN1 SPI1 SP140

1.49e-04178674cd85dcefe94ee742db64b63e105e13532321894a
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 RASSF10 ITPRIP TAL1

1.53e-041796749fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHC2 EFS KIF26A FOXJ1

1.59e-041816747af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellfacs-BAT-Fat-18m|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA ARHGEF1 STK24 SP140

1.63e-04182674efc335f4e566533cfbcd17262bd94ae64fa2e117
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA MEF2B SPI1 SP140

1.70e-0418467473ddf9d647d61381bab1e9c0d983736b6d390c15
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA MEF2B SPI1 SP140

1.77e-04186674124a618a0911aba9fc2a071dc3ca40fc003bb1ed
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRD2 PRRC2A IKZF4 FOXJ1

1.77e-04186674bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHC2 EGR4 SEZ6L2 NPAS4

1.77e-04186674f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RABEP2 NAPSA ARHGEF1 SP140

1.77e-04186674a8fcb440d88770f95678c5d28413fc4d847f42a8
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RABEP2 NAPSA ARHGEF1 SP140

1.77e-041866746b2d15e2756d4d4d68ad600e4a6c074edc3488f2
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MIER2 WDR81 ITPRIP SHANK3

1.88e-04189674bccb3481ffed597c845fe860da658505316105b5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRD2 PRRC2A IKZF4 FOXJ1

1.88e-04189674965e0e388251e7318f8b463816dc96ccb4658677
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NRXN2 COL6A6 KIF26A PLPPR3

1.88e-041896748e6b6025f5554672e26a5d19fe365acb4333789c
ToppCellmild-Others|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 TAL1

1.92e-04190674782dc1b612ac1faad7cc2781bfda92a079830d38
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A2 MYO3A NIBAN1 NPAS4

1.92e-04190674d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL4A2 KIF26A ALPK3 SHANK3

1.96e-04191674dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellmild-Others-Megakaryocytes|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 TAL1

1.96e-041916740b36223bd7f5758cc37194da6cc252f613bc3c97
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL4A2 ALPK3 ITPRIP SHANK3

2.00e-041926745af3b2b38495e925497c48f605d618bbf970965d
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 ITPRIP TAL1 SHANK3

2.00e-04192674e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellNS-critical-d_0-4-Myeloid-Neutrophil|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NIBAN1 R3HDM4 CPD ALPK1

2.00e-041926743db74359c30172a51177e00eac1f48f483e15578
ToppCellmoderate-Myeloid-Neutrophil|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NIBAN1 SPI1 R3HDM4 CPD

2.00e-041926748105408400dac5dcb0ce62b558433257559c9f09
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EFHC2 METRN PLPPR3 FOXJ1

2.04e-04193674e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 KIF26A TAL1 SHANK3

2.04e-04193674d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA METRN PLPPR3 FOXJ1

2.04e-04193674bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SPI1 R3HDM4 ALPK1 SP140

2.08e-04194674267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 ALPK1

2.08e-04194674ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 MYO3A NIBAN1 MEF2B

2.12e-04195674815ac5dacd382b11abb32011ed1c0635b0ddc779
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA MEF2B SPI1 SP140

2.12e-04195674e3df097e894b96b7d23db35bd527a8de6a055e52
ToppCellbackground-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 ITPRIP TAL1 SHANK3

2.12e-04195674c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC184 NRXN2 SYT3 SEZ6L2

2.12e-041956745a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell10x5'|World / Manually curated celltypes from each tissue

NAPSA BRD2 ARHGEF1 SP140

2.12e-04195674de28b998793271c4f69ce9e183c3e62d809e9cc8
ToppCellcontrol-Myeloid-Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 ALPK1

2.16e-041966749c8623232c47af5de9f360fd5c5113362e37c6c9
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIER2 COL4A2 ANKRD65 SHANK3

2.16e-04196674c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCellCOVID-19_Severe-Neu_0|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

NIBAN1 SPI1 CPD PLEKHG2

2.16e-041966744831243fcd680cf4821fa0246e758c3e7c13a962
ToppCellCOVID-19_Severe-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

NIBAN1 SPI1 CPD PLEKHG2

2.16e-041966744fdea41ac7d84f0c52d102d87a5fce620480985e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 TSPOAP1 ITPRIP MEX3C

2.16e-0419667408714b70ddaee7d11397c1dd4a287d412edd90f7
ToppCellmild-Myeloid-Neutrophils_4|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 ALPK1

2.16e-04196674f8c98cded5550843322b1711e1a57c7e88cae861
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 TSPOAP1 ITPRIP MEX3C

2.16e-041966745bcc959db7deb34d5a32d3464367d47d4945cdaf
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

EFHC2 NIBAN1 BRD2 STK24

2.16e-0419667409d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 TSPOAP1 ITPRIP MEX3C

2.20e-04197674f84263c5aaf3a5cd46d6e06358e8de6c6e6eaa3b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 NIBAN1 MEF2B NPAS4

2.20e-04197674cc494a656db868bb489238a5becc31bc8518f3cc
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EFHC2 DIPK1C PLPPR3 FOXJ1

2.20e-041976746e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellcontrol-Myeloid-Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 SPI1 R3HDM4 ALPK1

2.20e-041976748819db1550bf14566c6d33d97f7f83419e867ace
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NIBAN1 SPI1 CPD SP140

2.20e-041976743cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 NIBAN1 MEF2B NPAS4

2.20e-04197674b7e399b8e1a1ffc2b359f14929f199b93d9bbcce
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIER2 COL4A2 ANKRD65 SHANK3

2.20e-04197674947042f888335c0829d4d5daeb623973eadb3348
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EFHC2 MYO3A PLPPR3 FOXJ1

2.25e-04198674f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA ANKRD65 SPI1 MAGEF1

2.25e-04198674d0371e2ca9e25727b35985940f6228f9d8e49727
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 ITPRIP TAL1 SHANK3

2.25e-041986745c82dad416938d5c460069796d808170e7dbc8d9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA ANKRD65 SPI1 MAGEF1

2.25e-0419867408ad0bece508bb4f9cc126d94839b5c89ce21ba8
ToppCellwk_15-18-Epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NAPSA ANKRD65 RASSF10 FOXJ1

2.25e-0419867412bbe77c3d68bf1e545949dbb1eb49ed3641de3d
ToppCellTracheal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 ITPRIP TAL1 SHANK3

2.25e-0419867477e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRD2 R3HDM4 PPP1R3F IKZF4

2.25e-04198674d021d0edb6aba2f15c51a3ec4e08c7233d0c1962
ToppCellmLN-Dendritic_cell-cDC2|mLN / Region, Cell class and subclass

ANKRD65 SPI1 NRXN2 NFATC4

2.29e-04199674cb17bccb47d04f7793709f9a4376fcc8ce95430c
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MIER2 COL4A2 ITPRIP TAL1

2.29e-041996741621ce2968f3100e4c39e0ef8293232a5d76c614
ToppCellmLN-(5)_Dendritic_cell-(50)_cDC2|mLN / shred on region, Cell_type, and subtype

ANKRD65 SPI1 NRXN2 NFATC4

2.29e-041996748d1b18596a0965427abefe0be744c74e4c11d5d3
ToppCellTracheal-10x3prime_v2-Endothelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MIER2 COL4A2 TAL1 SHANK3

2.33e-042006742e51195810bca8a98488a8a06c538feaa27f1f28
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 COL4A2 ITPRIP TAL1

2.33e-042006747a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCelldistal-Endothelial-Capillary_Intermediate_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 ITPRIP TAL1 SHANK3

2.33e-0420067443bc48413b100a06f8edd9acd812296788fcbf5b
ToppCellsevere-Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NIBAN1 SPI1 R3HDM4 CPD

2.33e-04200674f04d5951bac4dee47c22aaf7973312ca797f322e
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MIER2 COL4A2 ITPRIP TAL1

2.33e-04200674746e8f61411f8e68b988152ab36561991f716a0a
ToppCellCOVID-19-COVID-19_Severe-Myeloid-Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

NIBAN1 SPI1 CPD ALPK1

2.33e-04200674fec2660c9a9977b3b3a2eaed063b9049c0b07ff2
ToppCelldistal-Endothelial-Capillary_Intermediate_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 ITPRIP TAL1 SHANK3

2.33e-042006744d6714d48738cdee7d535923f6dd2431e5304741
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C URB1 WDR81 PLCB3

2.33e-04200674fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-|Thalamus / BrainAtlas - Mouse McCarroll V32

NAPSA COL6A6 C16orf96

2.76e-048467339196f7af1a3199ca611acbe7b2e7a76d79c8fdd
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)|Thalamus / BrainAtlas - Mouse McCarroll V32

NAPSA COL6A6 C16orf96

2.76e-048467379cdb04e91aa119a128f0fef7a09b59a0edf00a0
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--|Thalamus / BrainAtlas - Mouse McCarroll V32

NAPSA COL6A6 C16orf96

2.76e-048467366fc8327fc9c0f9a135e874ad2056ca414cd5148
Diseasevenous thromboembolism, fibrinogen measurement

DCHS2 HNF1A SHANK3

4.42e-0467653EFO_0004286, EFO_0004623
Diseasesexual dimorphism measurement

HNF1A ZNF142 METRN NFATC4 ALPK3 CPD PLCB3 SEZ6L2 NPAS4

6.85e-041106659EFO_0021796
Diseasealcohol consumption measurement

HNF1A SPI1 KIF26A PLCB3 ALPK1 SEZ6L2 TAL1 STK24 ARMH4

1.54e-031242659EFO_0007878
Diseaseintelligence, response to cranial radiation therapy

DCHS2 GTF3C1

1.74e-0328652EFO_0004337, EFO_0010950
Diseasefibrinogen measurement

DCHS2 HNF1A SHANK3

1.81e-03109653EFO_0004623
DiseaseOvarian Mucinous Adenocarcinoma

MYO3A ALPK1

2.13e-0331652C1335167
Diseasecholine measurement

HNF1A SPI1 NFATC4

2.99e-03130653EFO_0010116
Diseasebitter alcoholic beverage consumption measurement

NRXN2 SEZ6L2 ARMH4

3.19e-03133653EFO_0010092
DiseaseDiabetic Nephropathy

HNF1A ALPK1

4.26e-0344652C0011881
Diseaseautism spectrum disorder (implicated_via_orthology)

MEF2B NRXN2 SHANK3

4.63e-03152653DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EPGDEGEPGRSGLEL

ARHGEF1

376

Q92888
LGEEAGEEPGGLPSL

C16orf86

266

Q6ZW13
GLDGDTELPGFTLPG

ARMH4

646

Q86TY3
SEGEGEVSPEGPGLL

ALPK3

1291

Q96L96
TEGDEAIKGLPGLPG

COL4A2

486

P08572
LGVLEDLGPSGPSEE

CUEDC2

36

Q9H467
GLLTGILPGLEEGSE

DOP1A

146

Q5JWR5
PGAGLLEGAPEGIQE

ALPK1

686

Q96QP1
GPELPDPLGGLLDEA

NFE2L1

431

Q14494
TLLETDGGLPGLEDG

R3HDM4

81

Q96D70
DGGLPGLEDGDLAPP

R3HDM4

86

Q96D70
EPLEPDGGPDGELLL

RASSF10

371

A6NK89
PLEPLEELSGDGGPA

RABEP2

206

Q9H5N1
LEGPGPEAGGLDREP

TSPOAP1

1826

O95153
LGGEEDELPGLGGAP

ITPRIP

116

Q8IWB1
DELPGLGGAPLQGLT

ITPRIP

121

Q8IWB1
LEEAGILRAGPGGPD

PCDHA11

821

Q9Y5I1
LPLLALGPTAGDGEG

MBD6

626

Q96DN6
EEEDLGGDGPRLGLL

MAGEF1

156

Q9HAY2
GALELLLAEGPGPAG

METRN

101

Q9UJH8
PTILELGEGPGSGEE

LRRC75A

296

Q8NAA5
VSDEKPGIGGEPLLG

EFHC2

36

Q5JST6
DLESELYLGGLPEGG

NRXN2

621

Q9P2S2
GQGGLIEEPTGDELP

HNF1A

181

P20823
LDPGGPPALDGSLGD

KIF26A

1141

Q9ULI4
GDLPQALPELGGGEK

ANKRD65

376

E5RJM6
PGDLGEGAEGLPGLL

EGR4

376

Q05215
RGIGLDGPELEPDEG

MEF2B

91

Q02080
LEGGEGDFALLPGGP

DCHS2

471

Q6V1P9
LLGEMPEGLGDGPLV

PLCB3

1191

Q01970
TGGLEPLGGLEPLDS

NPAS4

656

Q8IUM7
GTEPVPGLELGLELE

C16orf96

331

A6NNT2
AGLGSLIPEGDAGPD

CPD

101

O75976
GGELGALEALELSPP

FOXJ1

321

Q92949
GGTDEGIYDVPLLGP

EFS

246

O43281
LEEGGPPLTLGLEGE

FPGS

286

Q05932
GLLGGDGPLVEPLDM

CCDC184

166

Q52MB2
AGEGPEDLADGGPLL

IKZF4

421

Q9H2S9
AGIPGPDGLEGSLGL

COL6A6

1566

A6NMZ7
PPLSLLEEEAGEGGQ

DIPK1C

126

Q0P6D2
PLSVDGTAGGLDEPG

MIER2

401

Q8N344
GGDLDLLAQPLPADG

PAOX

446

Q6QHF9
PELPSEGGAGSGLLL

SYT3

186

Q9BQG1
KEAPPLGAGGLGEEL

NFATC4

21

Q14934
GGSALDLLEPGPLDE

STK24

116

Q9Y6E0
GGGGAPPDDLLQDVL

TAL1

271

P17542
LGLDEDLLGPGVAEG

PTDSS2

466

Q9BVG9
DLLGPGVAEGEGAPT

PTDSS2

471

Q9BVG9
SGGPELEGDGLLLRE

MEX3C

36

Q5U5Q3
GGRGPDELEGPDSKL

PRRC2A

211

P48634
APLGGPLGLDTLLDG

WIZ

676

O95785
EEELLVLAGGGSPGL

SEZ6L2

226

Q6UXD5
SDGEADGLEPGPGLL

SPI1

146

P17947
GPGLGLQGDLDDFLP

URB1

1256

O60287
LPGEGNAGLLGLGPE

BRD2

11

P25440
GGLTEEPLGPMEGEL

NIBAN1

801

Q9BZQ8
LGEEPVGGLGSLLDP

SHANK3

1511

Q9BYB0
LEGRGLGLPDDASPG

PLPPR3

416

Q6T4P5
LATGEGLPPLGAADG

PLPPR3

661

Q6T4P5
GLLPLGLEEPYGVDD

TECPR1

516

Q7Z6L1
TGAGDPILDPGLGLG

PPP1R3F

211

Q6ZSY5
PLPGREEEPGLGDSG

ZDHHC5

556

Q9C0B5
GEPEKGLCLLPGEGE

SP140

311

Q13342
EDYLGPLLDGGVLGL

PLEKHG2

126

Q9H7P9
LGLEGPDGLEGPELS

ZNF142

726

P52746
EGLIPGDGLGAAGLD

GTF3C1

1106

Q12789
LPLLPGFEGDISTGG

PLD2

681

O14939
PGEGEEGRILLPEGF

WDR81

711

Q562E7
AAEELLTGPGPGEAG

ZNF628

896

Q5EBL2
LGITAIELGDGDPPL

MYO3A

216

Q8NEV4
EEPDGGELVLGGSDP

NAPSA

226

O96009