Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSRCR

SSC5D CD5L CD163L1 DMBT1

6.31e-0721624PF00530
DomainSR

SSC5D CD5L CD163L1 DMBT1

1.32e-0625624SM00202
Domain-

SSC5D CD5L CD163L1 DMBT1

1.32e-06256243.10.250.10
DomainSRCR_1

SSC5D CD5L CD163L1 DMBT1

1.56e-0626624PS00420
DomainSRCR_2

SSC5D CD5L CD163L1 DMBT1

1.56e-0626624PS50287
DomainSRCR-like_dom

SSC5D CD5L CD163L1 DMBT1

1.56e-0626624IPR017448
DomainSRCR

SSC5D CD5L CD163L1 DMBT1

1.82e-0627624IPR001190
DomainTgfb1i1/Leupaxin

TGFB1I1 LPXN

1.08e-052622IPR017305
DomainLLGL

LLGL1 STXBP5

6.48e-054622PF08366
DomainLethal2_giant

LLGL1 STXBP5

6.48e-054622IPR000664
DomainLLGL2

LLGL1 STXBP5

6.48e-054622IPR013577
DomainWD40

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

2.59e-04268626SM00320
DomainWD40_repeat

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

2.80e-04272626IPR001680
DomainWD_REPEATS_1

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

3.15e-04278626PS00678
DomainWD_REPEATS_2

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

3.21e-04279626PS50082
DomainWD_REPEATS_REGION

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

3.21e-04279626PS50294
DomainWD40_repeat_dom

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

4.48e-04297626IPR017986
DomainCUB

TLL2 C1R DMBT1

5.76e-0449623PF00431
DomainCUB

TLL2 C1R DMBT1

6.11e-0450623SM00042
Domain-

TLL2 C1R DMBT1

6.86e-04526232.60.120.290
DomainCUB

TLL2 C1R DMBT1

7.25e-0453623PS01180
Domain-

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

8.15e-043336262.130.10.10
DomainWD40/YVTN_repeat-like_dom

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

8.41e-04335626IPR015943
DomainCUB_dom

TLL2 C1R DMBT1

8.97e-0457623IPR000859
DomainLIM

TGFB1I1 LPXN PXN

1.56e-0369623PF00412
Domain-

TGFB1I1 LPXN PXN

1.63e-03706232.10.110.10
DomainWD40

LLGL1 STXBP5 NBEAL2 EML1 PAK1IP1

1.68e-03259625PF00400
DomainZnf_LIM

TGFB1I1 LPXN PXN

1.70e-0371623IPR001781
DomainLIM_DOMAIN_1

TGFB1I1 LPXN PXN

1.70e-0371623PS00478
DomainLIM_DOMAIN_2

TGFB1I1 LPXN PXN

1.70e-0371623PS50023
DomainLIM

TGFB1I1 LPXN PXN

1.70e-0371623SM00132
DomainVWFC_1

DGCR2 CHRD

6.35e-0336622PS01208
DomainVWC

DGCR2 CHRD

7.06e-0338622SM00214
DomainVWFC_2

DGCR2 CHRD

7.06e-0338622PS50184
DomainVWF_dom

DGCR2 CHRD

8.57e-0342622IPR001007
Pubmed

GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin.

TGFB1I1 LPXN PXN

5.65e-08563317467235
Pubmed

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.

TGFB1I1 LPXN PXN

1.13e-07663310604475
Pubmed

Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.

TGFB1I1 LPXN PXN

4.72e-07963328935710
Pubmed

Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells.

SPI1 CIITA

3.23e-06263222112519
Pubmed

Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion.

TGFB1I1 PXN

3.23e-06263232859368
Pubmed

Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.

TGFB1I1 PXN

3.23e-06263227269065
Pubmed

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

HIF1A PXN

3.23e-06263225231004
Pubmed

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.

TGFB1I1 PXN

3.23e-06263221148292
Pubmed

BRAF(V600E) mutation influences hypoxia-inducible factor-1alpha expression levels in papillary thyroid cancer.

HIF1A BRAF

3.23e-06263220473281
Pubmed

Role of PU.1 in MHC Class II Expression via CIITA Transcription in Plasmacytoid Dendritic Cells.

SPI1 CIITA

3.23e-06263227105023
Pubmed

LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin.

LPXN PXN

9.68e-06363219917054
Pubmed

A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability.

LPXN PXN

9.68e-06363231537712
Pubmed

PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA.

SPI1 CIITA

9.68e-06363220363966
Pubmed

Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC.

TGFB1I1 LPXN

9.68e-06363238159847
Pubmed

The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling.

TGFB1I1 PXN

9.68e-06363211784865
Pubmed

Gp130-HIF1α axis-induced vascular damage is prevented by the short-term inhibition of IL-6 receptor signaling.

HIF1A IL6R

9.68e-06363238165930
Pubmed

Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.

TGFB1I1 PXN

9.68e-06363217233630
Pubmed

Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase.

TGFB1I1 PXN

9.68e-0636329756887
Pubmed

Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA.

TGFB1I1 PXN

1.93e-05463222629471
Pubmed

E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII).

SPI1 CIITA

1.93e-05463215242870
Pubmed

Renal cell carcinoma risk in type 2 von Hippel-Lindau disease correlates with defects in pVHL stability and HIF-1alpha interactions.

HIF1A RBX1

1.93e-05463216261165
Pubmed

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

HIF1A BRAF

1.93e-05463225193384
Pubmed

Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase.

TGFB1I1 PXN

1.93e-05463211463817
Pubmed

HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate.

HIF1A RBX1

1.93e-05463234537235
Pubmed

Hic-5 interacts with GIT1 with a different binding mode from paxillin.

TGFB1I1 PXN

1.93e-05463212153727
Pubmed

Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation.

SPI1 CIITA

1.93e-05463221216962
Pubmed

Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5.

TGFB1I1 PXN

1.93e-05463211805099
Pubmed

Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions.

TGFB1I1 PXN

1.93e-0546329422762
Pubmed

Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.

TGFB1I1 PXN

1.93e-05463225742295
Pubmed

FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.

HIF1A CIITA

1.93e-05463229238041
Pubmed

Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.

HIF1A SPI1

3.22e-05563220972335
Pubmed

RUNX1 regulates corepressor interactions of PU.1.

SPI1 CBFA2T3

3.22e-05563221518930
Pubmed

Distinct profile of HIF1α, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.

HIF1A BRAF

3.22e-05563224612059
Pubmed

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

HIF1A BRAF

3.22e-05563223563312
Pubmed

Cathepsin E: a novel target for regulation by class II transactivator.

SPI1 CIITA

3.22e-05563215100295
Pubmed

Differential recruitment of E3 ubiquitin ligase complexes regulates RET isoform internalization.

SHANK2 GRB10

3.22e-05563228794017
Pubmed

βTrCP interacts with the ubiquitin-dependent endocytosis motif of the GH receptor in an unconventional manner.

GHR RBX1

3.22e-05563223607312
Pubmed

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

TLL2 CHRD

3.22e-05563210479448
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

CCDC88A TKT DGKA CKAP4 ARMC6

3.28e-0520163525192599
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

TLL2 CHRD DGKA DMBT1 PNKD

4.05e-0521063516537572
Pubmed

CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10.

MCM10 RBX1

4.82e-05663222570418
Pubmed

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells.

SPI1 CIITA

4.82e-05663228002729
Pubmed

Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis.

SPI1 IL6R

4.82e-05663224429361
Pubmed

Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex.

HIF1A RBX1

6.74e-05763217132228
Pubmed

PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells.

SPI1 LY75

6.74e-05763210648399
Pubmed

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.

HIF1A RBX1

6.74e-05763222537386
Pubmed

SPOP inhibits BRAF-dependent tumorigenesis through promoting non-degradative ubiquitination of BRAF.

BRAF RBX1

8.98e-05863236585710
Pubmed

DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.

HIF1A RBX1

1.15e-04963223401859
Pubmed

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.

TGFB1I1 PXN

1.15e-04963210330411
Pubmed

Essential role of B-Raf in ERK activation during extraembryonic development.

HIF1A BRAF

1.44e-041063216432225
Pubmed

Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins.

GHR GRB10

1.44e-04106329632636
Pubmed

Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

HIF1A CBFA2T3

1.44e-041063225974097
Pubmed

A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression.

HIF1A RBX1

1.44e-041063221840486
Pubmed

Gestational loss and growth restriction by angiogenic defects in placental growth factor transgenic mice.

HIF1A BRAF

1.76e-041163225147341
Pubmed

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

GHR RBX1

2.11e-041263225505247
Pubmed

KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition.

HIF1A BRAF

2.11e-041263232405640
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

GHR CD5L C1R IL6R

2.34e-0416563414718574
Pubmed

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.

CCDC88A LLGL1 DMBT1

2.61e-046863314676191
Pubmed

A trans-eQTL network regulates osteoclast multinucleation and bone mass.

TGFB1I1 EML1

2.90e-041463232553114
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

CLCN5 IL6R

4.85e-04186329169421
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

GHR HIF1A BRAF PXN DGKA

5.69e-0437163525241761
Pubmed

Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier.

HIF1A SPI1

7.29e-042263232369453
Pubmed

Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.

DMBT1 RBX1

7.29e-042263226631746
Pubmed

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

LLGL1 PXN

7.29e-042263227521426
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

LLGL1 RNF115 RBX1 ARMC6

8.44e-0423263425515538
Pubmed

Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes.

HIF1A RBX1

8.69e-042463234195792
Pubmed

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

TLL2 CFAP43

1.18e-032863218839057
Pubmed

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.

CCDC88A ARSL

1.27e-032963221998595
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

TGFB1I1 ZHX3 SPI1 LPXN

1.34e-0326363420932939
Pubmed

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.

CACNG1 CCDC88A MCM10

1.43e-0312263331615875
Pubmed

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

CD5L SPI1

1.55e-03326329611252
Pubmed

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

LLGL1 GRB10

1.75e-033463215604097
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SSC5D CD163L1 LY75

4.61e-05274731253
GeneFamilyWD repeat domain containing

LLGL1 STXBP5 NBEAL2 CFAP43 EML1 PAK1IP1

5.71e-05262476362
GeneFamilyLIM domain containing

TGFB1I1 LPXN PXN

4.83e-04594731218
CoexpressionGSE29618_MONOCYTE_VS_PDC_UP

HIF1A SPI1 TKT PXN KDM7A CKAP4

8.42e-06199636M4945
CoexpressionGSE29618_PDC_VS_MDC_DN

HIF1A SPI1 CIITA TKT LY75 IL6R

8.66e-06200636M4952
CoexpressionTONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN

SPI1 CKAP4 CBFA2T3 SMOX IL6R

1.02e-04193635M4723
CoexpressionGSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP

DGCR2 STXBP5 PXN NHS LY75

1.07e-04195635M5334
CoexpressionGSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN

DGCR2 CLK4 GRB10 KDM7A CKAP4

1.10e-04196635M3448
CoexpressionGSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP

ARSL LPXN PXN SMOX IL6R

1.15e-04198635M8370
CoexpressionGSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN

ADPRM GRB10 CBFA2T3 IL6R RAPGEFL1

1.18e-04199635M8044
CoexpressionGSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP

NBEAL2 CLK4 KDM7A CBFA2T3 IL6R

1.18e-04199635M4460
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

SYT11 NBEAL2 CKAP4 CBFA2T3 IL6R

1.18e-04199635M9124
CoexpressionGSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP

CCDC88A PXN KDM7A CKAP4 IL6R

1.21e-04200635M318
CoexpressionGSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP

SPI1 CDIN1 NBEAL2 FADS6 ERI2

1.21e-04200635M7991
CoexpressionGSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP

CD5L SYT11 GRB10 PNKD IL6R

1.21e-04200635M7283
CoexpressionGSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN

STXBP5 DGKA LY75 SMOX IL6R

1.21e-04200635M7155
CoexpressionGSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP

CLCN5 SPI1 CIITA C1R CBFA2T3

1.21e-04200635M8532
CoexpressionGSE22886_NAIVE_BCELL_VS_MONOCYTE_DN

TKT PXN CKAP4 PAK1IP1 IL6R

1.21e-04200635M4486
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D

TGFB1I1 DGCR2 ZHX3 LPXN CHRD KDM7A ERI2 IL6R

1.53e-04646638M2419
ToppCellmild_COVID-19-Classical_Monocyte|World / disease group, cell group and cell class (v2)

HIF1A CCDC88A SPI1 TKT CCR1 CKAP4 IL6R

1.25e-081976375d826f4d7b7a46847c67e6bef38eb860bc808a6c
ToppCellmild_COVID-19_(asymptomatic)-Classical_Monocyte|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

HIF1A CCDC88A SPI1 TKT CCR1 CKAP4 IL6R

1.34e-0819963773a98d19871ffbc3c631de330998d42e9afa6da2
ToppCellPND10-Immune-Immune_Myeloid-DC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A SPI1 CIITA CCR1 CBFA2T3 LY75

9.46e-08157636ed387cf06d19e201a2a0dc4f3c796fcf8fa6637a
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CCDC88A SPI1 CIITA CBFA2T3 LY75 ARMC6

2.05e-0717963699894067e2c2a3ed53abdc5434410c3172693496
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A SPI1 TKT LPXN CCR1 LY75

2.12e-07180636cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A SPI1 TKT LPXN CCR1 LY75

2.26e-0718263694d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HIF1A CCDC88A SPI1 CIITA DGKA IL6R

3.29e-071946363043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SSC5D SPI1 CIITA NBEAL2 LY75 IL6R

3.29e-071946365a048bd2af30975fdc57ff40bc49aa5811c830d8
ToppCellmild_COVID-19-Classical_Monocyte|mild_COVID-19 / disease group, cell group and cell class (v2)

CCDC88A SPI1 TKT CCR1 CKAP4 IL6R

3.71e-071986365b31b6e008e05d6528656114fbe0ccae8ffe13b1
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIF1A SPI1 TKT NBEAL2 KDM7A CKAP4

3.82e-07199636b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Classical_monocytes|bone_marrow / Manually curated celltypes from each tissue

HIF1A CCDC88A SPI1 TKT CCR1 CKAP4

3.82e-071996362c747e9265594e12d46bd8c8de75c45e83144155
ToppCellsevere-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HIF1A CCDC88A SPI1 TKT CCR1 CKAP4

3.94e-07200636db7046741706376682d164c385c4701aebefc2e6
ToppCellsevere-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HIF1A CCDC88A SPI1 TKT CCR1 CKAP4

3.94e-07200636f46689940fdea500ce2457eec412dd2c46705819
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPI1 CIITA CCR1 CBFA2T3 IL6R

2.17e-0614863531a7c2b20970070b14d2b955020320a6f99db547
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPI1 CIITA CCR1 CBFA2T3 IL6R

2.47e-0615263527718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A CLCN5 CIITA CBFA2T3 IL6R

2.90e-06157635e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A CLCN5 CIITA CBFA2T3 IL6R

2.99e-06158635e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A SPI1 CFAP43 CBFA2T3 IL6R

3.18e-061606355c28121916a12dbc22ef2421040bdc9148a40b78
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A SPI1 CFAP43 CBFA2T3 IL6R

3.18e-06160635b7093678987575f2f99d648821d31b4a37075aca
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC88A SPI1 CIITA CBFA2T3 IL6R

3.69e-061656351c630f9ecde2e0243922a2be4b1ab5adcfcb0893
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

HIF1A PXN CCR1 KDM7A CKAP4

3.92e-061676357d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 CIITA FAM178B CCR1 ERI2

3.92e-06167635f5bffa77061baec0ba87bd688a047595f32534db
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 CIITA LPXN CCR1 CBFA2T3

4.27e-06170635138235227fc4c3d660c3a06e8e5167bf64f076b3
ToppCellwk_15-18-Hematologic-Myeloid-pre-pDC/DC5|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SPI1 CIITA LPXN CBFA2T3 IL6R

5.96e-06182635748401d2c84260a777001dd75b0182453185addc
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A CD5L TKT CCR1 LY75

6.28e-061846358e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD5L SPI1 CD163L1 CCR1 IL6R

7.34e-06190635e5625feb21915d4545cfad2659745ef180efcb1f
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD5L SPI1 CD163L1 CCR1 IL6R

7.34e-06190635912aa106581d1ed7e147c92f9a367e8e6b04052b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZHX3 SHANK2 CLCN5 ADAMTS17 NHS

7.34e-06190635cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

CCDC88A CD5L SPI1 CIITA CD163L1

7.53e-061916359c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPI1 TKT NBEAL2 KDM7A CKAP4

7.53e-06191635d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD5L SPI1 CD163L1 CCR1 IL6R

7.53e-06191635bce138f067b8962ecef1ddec6511a3f142d81d78
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HIF1A CCDC88A SPI1 CCR1 CKAP4

7.72e-06192635f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC88A SPI1 CIITA CBFA2T3 LY75

7.72e-061926358b4bbbadeac70f65378697120c754f10501b5651
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD5L SPI1 CD163L1 CCR1 IL6R

7.72e-061926354e3deefd30adb7bf1eba294610eed3d077aa9418
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIF1A CCDC88A SPI1 CCR1 CKAP4

7.72e-061926350219093e7921a0db78053aee13ec480b520f5662
ToppCellILEUM-inflamed-(3)_moDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CCDC88A SPI1 CD163L1 NHS CCR1

8.12e-06194635c9d2acab0bbcfa9a9113cf3b9f8147403f0beb43
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.33e-061956350110b976f98561ecd2e20ff6e7e3960a401bb7c2
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A SPI1 CIITA CD163L1 CCR1

8.33e-06195635f289a44010788853d7726d4b5aa75f3c62186c08
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.33e-06195635050fc59b328391d6e3ce23051764a842dcbb3144
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A SPI1 CIITA CD163L1 CBFA2T3

8.33e-0619563534a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellmyeloid-CD14+_Monocyte|World / Lineage and Cell class

HIF1A SPI1 TKT CCR1 CKAP4

8.54e-06196635b70f9402a1707671c0dd44226fa2adfc4bde8283
ToppCellILEUM-non-inflamed-(3)_moDC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CCDC88A SPI1 CIITA CD163L1 CCR1

8.54e-06196635e10f01172fd076d6892906853f9375d4c3058951
ToppCellmild_COVID-19_(asymptomatic)|World / disease group, cell group and cell class (v2)

HIF1A CCR1 CFAP43 IL6R RBX1

8.54e-061966358cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPI1 CIITA CD163L1 CCR1 IL6R

8.54e-06196635fa24d7c4b7c65e98b209db302a16c58ceac1a105
ToppCellNS-moderate-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HIF1A CCDC88A SPI1 CCR1 IL6R

8.75e-06197635774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A SPI1 CIITA CD163L1 CCR1

8.75e-06197635e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A SPI1 CIITA CD163L1 CBFA2T3

8.75e-06197635d95565652ca318a2298d6918d54ba6367e9560f4
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.75e-061976356e96a6c2576f52b72aeab1e41f47a0af05ff327a
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

CCDC88A SPI1 CIITA CBFA2T3 IL6R

8.75e-061976353388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.75e-06197635a80be1081f3ed0aceea69a33be21bca6bc354472
ToppCellbackground-Kupffer_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

CCDC88A CD5L SPI1 CD163L1 CCR1

8.75e-061976358b45c7ecc18d188abc8c172d9bf881c95617a46a
ToppCellCOVID-19_Moderate-Classical_Monocyte|World / disease group, cell group and cell class

HIF1A CCDC88A SPI1 CCR1 CKAP4

8.75e-0619763516cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635cf0fda1a24449cfd8ed56ffc7841d8accb187949
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635d347462ba6cb1c5a59c86dffbbe914cbc1e9cf16
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A SPI1 CIITA CD163L1 CBFA2T3

8.97e-0619863596883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635c5a22846bccff948f90bc1d5fe309907dcd08348
ToppCellCOVID-19_Mild-Myeloid-Classical_Monocyte|COVID-19_Mild / Disease group, lineage and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635e78d027a095473af555762a4d542a73f5bb2e166
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIF1A CCDC88A SPI1 CCR1 CKAP4

8.97e-0619863506201b34d3e38f22c93b759511f7b376504bac06
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-061986357e1f08dae11a7cc7949a5622d82c7e6660d06dea
ToppCellPBMC-Severe-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635a8338da2477ccf8e3d924de8dbe1056b98111532
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635525adc91fd8f2ad957b1879a5bf3950baa7d5ef8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635c49c71b34151d82b8795763bcb633c301c35f659
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPI1 CIITA CD163L1 CCR1 IL6R

8.97e-0619863579c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPI1 CIITA CD163L1 CCR1 IL6R

8.97e-0619863588635244a0b306d2cc50b8412fe47bb359c9cf00
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-0619863570e62d815b2a0aa5327ff94d6f4d503176e007b9
ToppCellCOVID-19_Severe-Myeloid-Classical_Monocyte|COVID-19_Severe / Disease group, lineage and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635dfe92577c7d1e63315c7564d5d99362c6e7d4d46
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-061986350128d00e6c3f99a026329dd169c0ea5e0e24c59c
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-061986354780f0276546962a2fc9f1041cfe49d2919d72b2
ToppCellsevere_COVID-19-Classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-0619863540dd3333945aa0c9120296b75155c621f462dbe8
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPI1 CIITA CD163L1 CCR1 IL6R

8.97e-06198635be038619157aeaa7a57ebd66392de940df4f8127
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-0619863551c220507bb05aa6338fec494b8ecf4902437708
ToppCellCOVID-19_Severe-Classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635b88c4c0ed1abf0a28dbe05b04b9bee1073855ba8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HIF1A CCDC88A SPI1 CCR1 CKAP4

8.97e-061986351ca91559fef231896e16180f5e050155c38f7cfa
ToppCellPBMC-Severe-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

8.97e-06198635603846129560d5d6e6df27d6168f67f592e5e6e2
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

HIF1A TKT PXN CCR1 CKAP4

8.97e-0619863530ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCellPBMC-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-0619963502256d86541be6851634283047fdc05fdf095114
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A SPI1 CIITA CD163L1 CBFA2T3

9.19e-0619963504adf46975aa4194ea40c7480f8a517def5d929c
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-061996359314eb9a89407738626a0384884454b5f9031ee7
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A SPI1 CIITA CD163L1 IL6R

9.19e-06199635f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC88A SPI1 CIITA CBFA2T3 IL6R

9.19e-0619963531825ba336603fe940dea6022e18ec25af110f4c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A CD5L SPI1 CD163L1 CCR1

9.19e-06199635e1066e638af83ba5e89c7cabb8ad00b6bcdee5f4
ToppCell10x5'-bone_marrow-Myeloid_Monocytic|bone_marrow / Manually curated celltypes from each tissue

HIF1A CCDC88A SPI1 TKT CCR1

9.19e-0619963562b0861faf173eead75678aad10d396cd0d80c2c
ToppCellHealthy/Control-Classical_Monocyte|World / Disease group and Cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-06199635527c767a09f911e319f7ad230b6518cebc0f367d
ToppCell3'_v3-bone_marrow-Myeloid_Monocytic|bone_marrow / Manually curated celltypes from each tissue

HIF1A CCDC88A SPI1 TKT CKAP4

9.19e-0619963551a766f823a9d50a3b1d59d0df2f5241a6b44c2b
ToppCellPBMC-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-0619963527667838e065370d4536eaaf5b42ad322a714b96
ToppCellCOVID-19_Mild-Myeloid|COVID-19_Mild / Disease group, lineage and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-06199635d0c230c3699955a80630b63ed18c770444c5dfe5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A CD5L SPI1 CD163L1 CCR1

9.19e-06199635ca0f6526ba0dcf8789dd3b583291519626427f2f
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A SPI1 CIITA LY75 IL6R

9.19e-061996357b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A SPI1 CIITA CD163L1 CCR1

9.19e-06199635a4785c1921a3de18a9190e4d674ede6a90f80004
ToppCellHealthy_donor-Classical_Monocyte|Healthy_donor / disease group, cell group and cell class (v2)

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-06199635af3a80dbf5e0306b80f420fd41f1aaed81fe9c46
ToppCellCOVID-19_Severe-Myeloid|COVID-19_Severe / Disease group, lineage and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-06199635babbf3220cc811a1794032e06c6cec4dfc7bff2f
ToppCellmild_COVID-19_(asymptomatic)-Classical_Monocyte|World / disease group, cell group and cell class (v2)

HIF1A SPI1 CCR1 CKAP4 IL6R

9.19e-06199635727122b6f4ca265d2826c9271b10a4215a9d45a3
ToppCellHealthy/Control-Classical_Monocyte|Healthy/Control / Disease group and Cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-061996354e8c7445d32fd2b7a50524dcd52141e76850c3df
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88A SPI1 TKT CCR1 CKAP4

9.19e-06199635dbf0bf09896c46155ae6fbd6307f097799e7e34e
ToppCell3'_v3-bone_marrow-Myeloid_Monocytic-Classical_monocytes|bone_marrow / Manually curated celltypes from each tissue

HIF1A CCDC88A SPI1 TKT CKAP4

9.19e-0619963593f25e8f22deb438c930c2e95e572dbd16503f71
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

CCDC88A SPI1 TKT CCR1 CKAP4

9.41e-06200635621af09aae34226902c03edf556562f3ab35a7d8
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HIF1A CCDC88A SPI1 CIITA CCR1

9.41e-06200635934c2efc780318c66d667ca75be0de350361d351
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A SPI1 CIITA CD163L1 CCR1

9.41e-06200635ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellsevere-HLA-DR-_S100A+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.41e-06200635a5eb50cbf3e94f0b3aa0fbef888989a11cffea37
ToppCellCOVID-19-COVID-19_Mild-Myeloid-CD14+_Monocyte|COVID-19_Mild / Disease, condition lineage and cell class

CCDC88A SPI1 TKT CCR1 CKAP4

9.41e-06200635f76d3647f8ab5f7be018b0697c911597198e03f5
DiseaseMelanoma, Cloudman S91

BRAF PXN

8.77e-057612C0009075
DiseaseMelanoma, Experimental

BRAF PXN

8.77e-057612C0025205
DiseaseMelanoma, B16

BRAF PXN

8.77e-057612C0004565
DiseaseMelanoma, Harding-Passey

BRAF PXN

8.77e-057612C0018598
DiseaseNon-Small Cell Lung Carcinoma

HIF1A BRAF PXN IL6R

3.10e-04156614C0007131
Diseasesquamous cell lung carcinoma, family history of lung cancer

GHR SPI1 GRB10

7.36e-0485613EFO_0000708, EFO_0006953
DiseaseGlioma

CLCN5 BRAF DMBT1

7.87e-0487613C0017638
DiseaseCerebral Astrocytoma

HIF1A BRAF

1.22e-0325612C0750935
DiseaseIntracranial Astrocytoma

HIF1A BRAF

1.22e-0325612C0750936
DiseasePilocytic Astrocytoma

HIF1A BRAF

1.22e-0325612C0334583
DiseaseAstrocytoma

HIF1A BRAF

1.22e-0325612C0004114
DiseaseJuvenile Pilocytic Astrocytoma

HIF1A BRAF

1.22e-0325612C0280783
DiseaseDiffuse Astrocytoma

HIF1A BRAF

1.22e-0325612C0280785
DiseaseGrade I Astrocytoma

HIF1A BRAF

1.22e-0325612C1704230
DiseaseSubependymal Giant Cell Astrocytoma

HIF1A BRAF

1.22e-0325612C0205768
DiseaseMixed oligoastrocytoma

HIF1A BRAF

1.22e-0325612C0547065
DiseaseChildhood Cerebral Astrocytoma

HIF1A BRAF

1.22e-0325612C0338070
DiseaseGemistocytic astrocytoma

HIF1A BRAF

1.32e-0326612C0334581
DiseaseProtoplasmic astrocytoma

HIF1A BRAF

1.32e-0326612C0334580
DiseaseFibrillary Astrocytoma

HIF1A BRAF

1.32e-0326612C0334582
DiseaseAnaplastic astrocytoma

HIF1A BRAF

1.43e-0327612C0334579
Diseasecortical thickness, neuroimaging measurement

GRB10 EML1 PNKD

1.55e-03110613EFO_0004346, EFO_0004840
DiseaseMalignant neoplasm of breast

HIF1A MAN2C1 LLGL1 BRAF OBSCN NHS SMOX RNF115

1.60e-031074618C0006142
Diseaseneutrophil count

CD5L SPI1 STXBP5 NBEAL2 NUP88 CBFA2T3 LY75 PNKD RAPGEFL1

2.04e-031382619EFO_0004833

Protein segments in the cluster

PeptideGeneStartEntry
HSVTASGAEHWREVC

SYT11

401

Q9BT88
DFESTCWNDGKHHHS

ERI2

41

A8K979
WCEGSSLYHHLHIIE

BRAF

531

P15056
ETFAWCRSHSHQGHG

CFAP43

671

Q8NDM7
WHLGLNCESASDHCH

ARSL

146

P51690
LVAAAAFSGWCVHHV

CKAP4

116

Q07065
HCAHEAEEAGIWQHV

CIITA

811

P33076
HHGHHTDVVREACWA

ARMC6

231

Q6NXE6
WSHECVVCFFAGHTH

ADPRM

266

Q3LIE5
QHRFWGFHDCTHQED

CD5L

326

O43866
EHSGWGKHNCVHRED

CD163L1

556

Q9NR16
LHSFTAVCQDDGTWH

C1R

351

P00736
IGHHGERSLESFCHW

ADAMTS17

296

Q8TE56
HHNTTCEAAHFGLWR

CACNG1

41

Q06432
AWGVCNHAFHFHCIS

RBX1

71

P62877
DSSLHLWEIVHHNGC

LLGL1

96

Q15334
LCFEVFEHLGTHGWE

ESPNL

881

Q6ZVH7
WFHGSCVGVEEHHAV

KDM7A

61

Q6ZMT4
HSHRDVCARHSWASD

LINS1

581

Q8NG48
SATWKVLHCTGHIHV

HIF1A

186

Q16665
HSSGEFSLLHDHEAW

CCDC88A

1621

Q3V6T2
TGLHCVWCHLEIHDD

DGKA

296

P23743
DGTWHHDCILDEDHS

LY75

176

O60449
ALGQSWHPEHFVCTH

LPXN

166

O60711
TCVSEQHEYHWHDGV

MCM10

796

Q7L590
CGSFCQHRDWEKHHH

CBFA2T3

576

O75081
QFECETSEAHVHVHW

OBSCN

816

Q5VST9
TWHPEHFVCTHCQEE

PXN

376

P49023
KDLQHHCVIHDAWSG

IL6R

271

P08887
HCVIHDAWSGLRHVV

IL6R

276

P08887
RETFSCHWTDEVHHG

GHR

61

P10912
CHWTDEVHHGTKNLG

GHR

66

P10912
WEFTHHTCSLHFPHE

CCR1

176

P32246
DECSHHAYLHDQFWS

CDIN1

221

Q9Y2V0
FNHEHCCWNSEHVTF

CLCN5

166

P51795
HHDLHSWHAESCYEK

DGCR2

246

P98153
HTIHATGHCHIDTAW

MAN2C1

251

Q9NTJ4
SHCVDDNSWTLVEHH

GRB10

201

Q13322
CGHDKHATLWDAVGH

EML1

561

O00423
LEWFDHHGHVCIVFE

CLK4

226

Q9HAZ1
STSVHHVLIWIHCFT

GPR139

176

Q6DWJ6
WLSHNCGHHEDAGVI

DMBT1

686

Q9UGM3
WLSHNCGHHEDAGVI

DMBT1

1206

Q9UGM3
DWAFGHSIISCHVEH

FADS6

281

Q8N9I5
HCTHEAGVHSVGLTW

NUP88

406

Q99567
LLSTTGHWHDFAHLE

MROH5

951

Q6ZUA9
TTTTHFAELWGHLDH

RNF115

66

Q9Y4L5
VAILCTHKHWDHSGG

PNKD

166

Q8N490
SEWNYLHHHHDASCR

NHS

721

Q6T4R5
ELCCTLSWVSDHHHN

FAM178B

491

Q8IXR5
SFADSAWHCVAIVHV

NBEAL2

671

Q6ZNJ1
WDFHPHHVHSEFESF

SPI1

51

P17947
HRGWKAHICSHEEDA

SSC5D

101

A1L4H1
HSVAWHHEGKQFICS

STXBP5

241

Q5T5C0
HEHATVCCKDENGWH

SHANK2

286

Q9UPX8
AAGHAWLSLDTHCHL

CHRD

551

Q9H2X0
PCHHITSHCTWVAAH

CLUHP3

86

Q96NS8
CEAFGWHAIIVDGHS

TKT

206

P29401
HATFELGATWIHGSH

SMOX

71

Q9NWM0
AHELGHVVGFWHEHT

TLL2

241

Q9Y6L7
FLHHWDVTEAVFHSL

TEX10

726

Q9NXF1
DHEQWTLVADFTHHA

PAK1IP1

26

Q9NWT1
CDKGFFHISELHIHW

ZNF664

36

Q8N3J9
ALGTHWHPEHFCCVS

TGFB1I1

301

O43294
HLTAFHWELFRCVHE

RAPGEFL1

431

Q9UHV5
LHNATCHSGEASFVW

ZHX3

126

Q9H4I2