Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidase activity	USP34 ADAM15 USP9Y F9 TMPRSS11B PRSS46P USP44 USP31 KLK9 KLK5 USP36 NRIP2 PRSS12 NLRP1 ADAM30 USP46 ADAM12 ADAMTS7 SENP6 TMPRSS2 CORIN	4.08e-06	654	205	21	GO:0008233
GeneOntologyMolecularFunction	phosphopyruvate hydratase activity	ENO1 ENO2 ENO3	4.23e-06	4	205	3	GO:0004634
GeneOntologyMolecularFunction	endopeptidase activity	USP34 ADAM15 F9 TMPRSS11B PRSS46P KLK9 KLK5 NRIP2 PRSS12 NLRP1 ADAM30 ADAM12 ADAMTS7 SENP6 TMPRSS2 CORIN	1.01e-05	430	205	16	GO:0004175
GeneOntologyCellularComponent	phosphopyruvate hydratase complex	ENO1 ENO2 ENO3	3.75e-06	4	206	3	GO:0000015
GeneOntologyCellularComponent	nuclear envelope	CENPF INPP4A RRM1 NUP205 NRXN1 RRP12 ALOX5 RANBP2 IFFO1 SYNE1 PARP8 MTMR8 TNKS NUP188 ENO1 SORL1	1.45e-04	560	206	16	GO:0005635
GeneOntologyCellularComponent	glutamatergic synapse	CTTNBP2 INPP4A LRRK2 ABHD6 DAPK1 CLSTN2 NRXN1 SNX6 BEGAIN GPM6A OGT PRSS12 DOCK10 ITGA8 USP46 LRP1 RIMS1 CTNND1 FBXL20 AGRN	1.76e-04	817	206	20	GO:0098978
GeneOntologyCellularComponent	nuclear pore inner ring	NUP205 NUP188	2.88e-04	3	206	2	GO:0044611
GeneOntologyCellularComponent	nuclear membrane	CENPF INPP4A NUP205 NRXN1 RRP12 ALOX5 RANBP2 IFFO1 SYNE1 TNKS ENO1	7.22e-04	349	206	11	GO:0031965
GeneOntologyCellularComponent	growth cone	LRRK2 NRXN1 GPM6A EXOC8 LRP1 CTNND1 ENO1 ENO2 AGRN	7.53e-04	245	206	9	GO:0030426
GeneOntologyCellularComponent	organelle envelope	CENPF INPP4A LRRK2 ABHD6 RRM1 NUP205 CSDE1 SLC8B1 NRXN1 RRP12 ALOX5 CCS RANBP2 OGT IFFO1 SYNE1 PARP8 MTMR8 ZNFX1 CPT1B SLC8A3 MTX2 TNKS TRAF3IP3 NUP188 ENO1 SORL1	9.16e-04	1435	206	27	GO:0031967
GeneOntologyCellularComponent	site of polarized growth	LRRK2 NRXN1 GPM6A EXOC8 LRP1 CTNND1 ENO1 ENO2 AGRN	9.45e-04	253	206	9	GO:0030427
GeneOntologyCellularComponent	cell cortex region	GPSM2 NLRP5 RIMS1 CTNND1	9.95e-04	45	206	4	GO:0099738
GeneOntologyCellularComponent	axonal growth cone	NRXN1 GPM6A LRP1 AGRN	9.95e-04	45	206	4	GO:0044295
Domain	EGF_3	ADAM15 SSPOP F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE ADAM30 ADAM12 DLL3 LRP1 LTBP3 AGRN SORL1	6.39e-09	235	203	16	PS50026
Domain	EGF_2	ADAM15 SSPOP F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE ADAM30 ADAM12 DLL3 LRP1 LTBP3 AGRN SORL1	3.49e-08	265	203	16	PS01186
Domain	EGF-like_dom	ADAM15 F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE ADAM30 ADAM12 DLL3 LRP1 LTBP3 AGRN SORL1	9.76e-08	249	203	15	IPR000742
Domain	EGF_1	ADAM15 SSPOP F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE ADAM30 ADAM12 DLL3 LRP1 LTBP3 AGRN	1.33e-07	255	203	15	PS00022
Domain	EGF-like_CS	ADAM15 F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE ADAM30 ADAM12 DLL3 LRP1 LTBP3 AGRN SORL1	1.80e-07	261	203	15	IPR013032
Domain	Enolase_N	ENO1 ENO2 ENO3	1.27e-06	3	203	3	PF03952
Domain	Enolase	ENO1 ENO2 ENO3	1.27e-06	3	203	3	IPR000941
Domain	Enolase_C	ENO1 ENO2 ENO3	1.27e-06	3	203	3	IPR020810
Domain	Enolase_N	ENO1 ENO2 ENO3	1.27e-06	3	203	3	IPR020811
Domain	Enolase_CS	ENO1 ENO2 ENO3	1.27e-06	3	203	3	IPR020809
Domain	Enolase_C	ENO1 ENO2 ENO3	1.27e-06	3	203	3	PF00113
Domain	Enolase_N	ENO1 ENO2 ENO3	1.27e-06	3	203	3	SM01193
Domain	Enolase_C	ENO1 ENO2 ENO3	1.27e-06	3	203	3	SM01192
Domain	ENOLASE	ENO1 ENO2 ENO3	1.27e-06	3	203	3	PS00164
Domain	EGF	ADAM15 F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 SELE DLL3 LRP1 LTBP3 AGRN SORL1	1.86e-06	235	203	13	SM00181
Domain	LRR_6	NLRC5 NLRP5 NLRP1 NLRP3 RNH1 LRRC31 FBXL20	2.11e-06	55	203	7	PF13516
Domain	-	ENO1 ENO2 ENO3	5.02e-06	4	203	3	3.30.390.10
Domain	-	ENO1 ENO2 ENO3	5.02e-06	4	203	3	3.20.20.120
Domain	Enolase_C-like	ENO1 ENO2 ENO3	5.02e-06	4	203	3	IPR029065
Domain	Enolase_N-like	ENO1 ENO2 ENO3	5.02e-06	4	203	3	IPR029017
Domain	EGF_CA	F9 FBN1 FBN2 JAG1 NOTCH2 DLL3 LRP1 LTBP3 AGRN	7.50e-06	122	203	9	SM00179
Domain	EGF-like_Ca-bd_dom	F9 FBN1 FBN2 JAG1 NOTCH2 DLL3 LRP1 LTBP3 AGRN	8.56e-06	124	203	9	IPR001881
Domain	hEGF	FBN2 JAG1 NOTCH2 DLL3 LTBP3	1.16e-05	28	203	5	PF12661
Domain	ASX_HYDROXYL	F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 LRP1 LTBP3	1.34e-05	100	203	8	PS00010
Domain	TRYPSIN_HIS	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	1.67e-05	103	203	8	IPR018114
Domain	EGF-type_Asp/Asn_hydroxyl_site	F9 FBN1 FBN2 NRXN1 JAG1 NOTCH2 LRP1 LTBP3	2.06e-05	106	203	8	IPR000152
Domain	TRYPSIN_HIS	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	2.20e-05	107	203	8	PS00134
Domain	Peptidase_S1A	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	3.27e-05	113	203	8	IPR001314
Domain	TRYPSIN_DOM	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	3.71e-05	115	203	8	PS50240
Domain	Tryp_SPc	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	4.20e-05	117	203	8	SM00020
Domain	TB	FBN1 FBN2 LTBP3	4.29e-05	7	203	3	PF00683
Domain	Trypsin_dom	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	5.34e-05	121	203	8	IPR001254
Domain	Trypsin	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	5.34e-05	121	203	8	PF00089
Domain	Peptidase_S1_PA	F9 TMPRSS11B PRSS46P KLK9 KLK5 PRSS12 TMPRSS2 CORIN	6.00e-05	123	203	8	IPR009003
Domain	-	FBN1 FBN2 LTBP3	6.81e-05	8	203	3	3.90.290.10
Domain	LDLR_class-A_CS	SSPOP LRP1 TMPRSS2 CORIN SORL1	6.97e-05	40	203	5	IPR023415
Domain	EGF	F9 NRXN1 JAG1 NOTCH2 SELE DLL3 LRP1 AGRN	7.12e-05	126	203	8	PF00008
Domain	USP_CS	USP34 USP9Y USP44 USP31 USP36 USP46	8.09e-05	66	203	6	IPR018200
Domain	EGF_Ca-bd_CS	F9 FBN1 FBN2 JAG1 NOTCH2 LRP1 LTBP3	9.08e-05	97	203	7	IPR018097
Domain	TB_dom	FBN1 FBN2 LTBP3	1.01e-04	9	203	3	IPR017878
Domain	TB	FBN1 FBN2 LTBP3	1.01e-04	9	203	3	PS51364
Domain	NACHT	NLRC5 NLRP5 NLRP1 NLRP3	1.02e-04	23	203	4	PS50837
Domain	NACHT_NTPase	NLRC5 NLRP5 NLRP1 NLRP3	1.02e-04	23	203	4	IPR007111
Domain	EGF_CA	F9 FBN1 FBN2 JAG1 NOTCH2 LRP1 LTBP3	1.03e-04	99	203	7	PS01187
Domain	USP_1	USP34 USP9Y USP44 USP31 USP36 USP46	1.13e-04	70	203	6	PS00972
Domain	UCH	USP34 USP9Y USP44 USP31 USP36 USP46	1.22e-04	71	203	6	PF00443
Domain	USP_2	USP34 USP9Y USP44 USP31 USP36 USP46	1.22e-04	71	203	6	PS00973
Domain	USP_3	USP34 USP9Y USP44 USP31 USP36 USP46	1.32e-04	72	203	6	PS50235
Domain	USP_dom	USP34 USP9Y USP44 USP31 USP36 USP46	1.32e-04	72	203	6	IPR028889
Domain	Peptidase_C19_UCH	USP34 USP9Y USP44 USP31 USP36 USP46	1.32e-04	72	203	6	IPR001394
Domain	-	SSPOP LRP1 TMPRSS2 CORIN SORL1	1.38e-04	46	203	5	4.10.400.10
Domain	SR	PRSS12 CD5 TMPRSS2 CORIN	1.43e-04	25	203	4	SM00202
Domain	TRYPSIN_SER	F9 TMPRSS11B KLK9 KLK5 PRSS12 TMPRSS2 CORIN	1.59e-04	106	203	7	PS00135
Domain	cEGF	FBN1 FBN2 LRP1 LTBP3	1.68e-04	26	203	4	PF12662
Domain	SRCR-like_dom	PRSS12 CD5 TMPRSS2 CORIN	1.68e-04	26	203	4	IPR017448
Domain	SRCR_1	PRSS12 CD5 TMPRSS2 CORIN	1.68e-04	26	203	4	PS00420
Domain	cEGF	FBN1 FBN2 LRP1 LTBP3	1.68e-04	26	203	4	IPR026823
Domain	SRCR_2	PRSS12 CD5 TMPRSS2 CORIN	1.68e-04	26	203	4	PS50287
Domain	LDLRA_1	SSPOP LRP1 TMPRSS2 CORIN SORL1	1.69e-04	48	203	5	PS01209
Domain	LDrepeatLR_classA_rpt	SSPOP LRP1 TMPRSS2 CORIN SORL1	1.87e-04	49	203	5	IPR002172
Domain	LDLa	SSPOP LRP1 TMPRSS2 CORIN SORL1	1.87e-04	49	203	5	SM00192
Domain	LDLRA_2	SSPOP LRP1 TMPRSS2 CORIN SORL1	1.87e-04	49	203	5	PS50068
Domain	SRCR	PRSS12 CD5 TMPRSS2 CORIN	1.95e-04	27	203	4	IPR001190
Domain	EGF_CA	FBN1 FBN2 JAG1 NOTCH2 LRP1 LTBP3	3.50e-04	86	203	6	PF07645
Domain	LUC7	LUC7L LUC7L2	3.50e-04	3	203	2	PF03194
Domain	Luc7-rel	LUC7L LUC7L2	3.50e-04	3	203	2	IPR004882
Domain	FBN	FBN1 FBN2	3.50e-04	3	203	2	IPR011398
Domain	TRYPSIN_SER	F9 KLK9 KLK5 PRSS12 TMPRSS2 CORIN	4.47e-04	90	203	6	IPR033116
Domain	LY	LRP1 ROS1 SORL1	5.23e-04	15	203	3	SM00135
Domain	LDLR_classB_rpt	LRP1 ROS1 SORL1	5.23e-04	15	203	3	IPR000033
Domain	-	CLSTN2 NRXN1 COL5A1 COL16A1 LGALS8 AGRN	5.96e-04	95	203	6	2.60.120.200
Domain	ROC_dom	LRRK2 DAPK1	6.95e-04	4	203	2	IPR020859
Domain	ROC	LRRK2 DAPK1	6.95e-04	4	203	2	PS51424
Domain	Leu-rich_rpt	LRRK2 TLR6 NLRC5 NLRP5 NLRP1 NLRP3 RNH1 LRRC31 LRRC8B FBXL20	7.90e-04	271	203	10	IPR001611
Domain	Pep_M12B_propep	ADAM15 ADAM30 ADAM12 ADAMTS7	8.27e-04	39	203	4	PF01562
Domain	Peptidase_M12B_N	ADAM15 ADAM30 ADAM12 ADAMTS7	8.27e-04	39	203	4	IPR002870
Domain	DISINTEGRIN_1	ADAM15 ADAM30 ADAM12 ADAMTS7	9.12e-04	40	203	4	PS00427
Domain	Reprolysin	ADAM15 ADAM30 ADAM12 ADAMTS7	9.12e-04	40	203	4	PF01421
Domain	ADAM_MEPRO	ADAM15 ADAM30 ADAM12 ADAMTS7	9.12e-04	40	203	4	PS50215
Domain	DISINTEGRIN_2	ADAM15 ADAM30 ADAM12 ADAMTS7	9.12e-04	40	203	4	PS50214
Domain	Peptidase_M12B	ADAM15 ADAM30 ADAM12 ADAMTS7	9.12e-04	40	203	4	IPR001590
Domain	ADAM_CR	ADAM15 ADAM30 ADAM12	9.15e-04	18	203	3	PF08516
Domain	Disintegrin_dom	ADAM15 ADAM30 ADAM12 ADAMTS7	1.00e-03	41	203	4	IPR001762
Domain	Leu-rich_rpt_Cys-con_subtyp	NLRC5 RNH1 FBXL20	1.08e-03	19	203	3	IPR006553
Domain	LRR_CC	NLRC5 RNH1 FBXL20	1.08e-03	19	203	3	SM00367
Domain	DSL	JAG1 DLL3	1.15e-03	5	203	2	PS51051
Domain	Notch_ligand_N	JAG1 DLL3	1.15e-03	5	203	2	IPR011651
Domain	MNNL	JAG1 DLL3	1.15e-03	5	203	2	PF07657
Domain	DSL	JAG1 DLL3	1.15e-03	5	203	2	IPR001774
Domain	-	ADAM15 ADAM30 ADAM12	1.26e-03	20	203	3	4.10.70.10
Domain	Ldl_recept_a	SSPOP LRP1 CORIN SORL1	1.42e-03	45	203	4	PF00057
Domain	Disintegrin	ADAM15 ADAM30 ADAM12	1.46e-03	21	203	3	PF00200
Domain	SRCR	PRSS12 CD5 TMPRSS2	1.46e-03	21	203	3	PF00530
Domain	DISIN	ADAM15 ADAM30 ADAM12	1.46e-03	21	203	3	SM00050
Domain	Growth_fac_rcpt_	FBN1 FBN2 JAG1 NOTCH2 DLL3 LRP1 LTBP3	1.61e-03	156	203	7	IPR009030
Domain	DAPIN	NLRP5 NLRP1 NLRP3	1.67e-03	22	203	3	PS50824
Domain	PYRIN	NLRP5 NLRP1 NLRP3	1.67e-03	22	203	3	SM01289
Domain	PYRIN	NLRP5 NLRP1 NLRP3	1.67e-03	22	203	3	PF02758
Domain	DAPIN	NLRP5 NLRP1 NLRP3	1.67e-03	22	203	3	IPR004020
Domain	Pectin_lyas_fold	FBXO10 PKHD1	1.71e-03	6	203	2	IPR012334
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	ITGA7 FBN1 COL5A1 COL16A1 COL6A6 ITGA8 AGRN	4.08e-05	85	155	7	M16441
Pathway	REACTOME_GLUCOSE_METABOLISM	PFKP NUP205 RANBP2 NUP188 ENO1 ENO2 ENO3	4.08e-05	85	155	7	M1870
Pathway	PID_NOTCH_PATHWAY	SSPOP JAG1 NOTCH2 ADAM12 DLL3 ENO1	4.47e-05	59	155	6	M17
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAM15 ITGA7 FBN1 FBN2 NRXN1 COL5A1 COL16A1 COL6A6 ITGA8 ADAM12 LTBP3 AGRN	1.19e-04	300	155	12	M610
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAM15 ITGA7 FBN1 FBN2 COL5A1 COL16A1 COL6A6 ITGA8 ADAM12 LTBP3 AGRN	1.32e-04	258	155	11	MM14572
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOLYSIS	PFKP ENO1 ENO2 ENO3	1.49e-04	25	155	4	M47623
Pathway	REACTOME_ECM_PROTEOGLYCANS	ITGA7 COL5A1 COL6A6 ITGA8 AGRN	1.59e-04	47	155	5	MM14925
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	CHUK JAG1 NOTCH2 DLL3	2.03e-04	27	155	4	M39545
Pathway	REACTOME_GLUCOSE_METABOLISM	PFKP NUP205 RANBP2 NUP188 ENO2 ENO3	2.82e-04	82	155	6	MM15394
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CTTNBP2 CENPF DAPK1 LUZP1 SBF1 NRXN1 KIF11 BEGAIN GPM6A RANBP2 DMXL2 OGT SYNE1 ZNFX1 AGO1 LRP1 UBA6 ZFR TNKS RIMS1 CTNND1 ENO1 AGRN	2.68e-08	963	211	23	28671696
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	KDM3B CDC45 CSDE1 SBF1 MID1 RALGDS DMXL2 OGT DOCK10 ZNFX1 MAP3K6 RFWD3 EXOC8 LIG4 ARAP3 LUC7L2 AGRN SORL1	1.10e-07	650	211	18	38777146
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP34 USP44 USP31 USP36 USP46	2.41e-07	23	211	5	14715245
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 ATP6V0A1 DCAF8 BACH1 FTCD USP9Y CHUK CSDE1 FBN1 SNX6 SACS GPSM2 PIP4P2 DMXL2 OGT SYNE1 ZNFX1 DNAAF9 THAP4 ARHGAP5 LRP1 SENP6 RORB TNKS LTBP3	3.22e-07	1285	211	25	35914814
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	LRRK2 LUZP1 MID1 PKHD1 KIF11 NLRP5 DOCK10 SENP6 RIMS1 SORL1	6.45e-07	208	211	10	33230847
Pubmed	A Moonlighting Human Protein Is Involved in Mitochondrial Import of tRNA.	ENO1 ENO2 ENO3	8.77e-07	4	211	3	25918939
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	FBN1 FBN2 ALMS1 ARHGAP29 PIBF1 NOTCH2 CCDC14 LUC7L2 LRP1	2.05e-06	184	211	9	32908313
Pubmed	Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3.	BTG2 CXCL2 CXCL3	2.18e-06	5	211	3	28018222
Pubmed	Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neurons.	BTG2 CXCL2 CXCL3	2.18e-06	5	211	3	23115191
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	USP34 DCAF8 PFKP LUZP1 NUP205 CDC45 FBN2 SBF1 SNX6 UPP1 KIF11 RANBP2 OGT MTMR8 EXOC8 ARAP3 LRP1 TNKS NUP188 SORL1	2.34e-06	974	211	20	28675297
Pubmed	Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain.	SELE CXCL2 CXCL3	4.34e-06	6	211	3	25445193
Pubmed	Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells.	ENO1 ENO2 ENO3	4.34e-06	6	211	3	19433310
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DCAF8 CACNA2D2 INPP4A SSPOP CSDE1 PHKB EXD3 BTG2 SLC8B1 NLRC5 NOTCH2 COL5A1 OGT XRCC2 THAP4 LUC7L LRP1 UBA6 DIP2C TMPRSS2 RIMS1 GREB1 CTNND1 ABLIM2 VPS13B	4.51e-06	1489	211	25	28611215
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	SSPOP FBN1 FBN2 NRXN1 LRP1 LTBP3	4.79e-06	71	211	6	33541421
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 SPAM1 DCAF8 CLSTN2 TRIP4 LUZP1 FBN2 TRAFD1 ALMS1 NOTCH2 WDR72 USP36 OGT SETDB2 RNH1 LUC7L2 LRP1 LRRC8B TRAF3IP3 NUP188 SORL1	5.02e-06	1116	211	21	31753913
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	DCAF8 TMEM94 INPP4A PHKB RANBP2 ARHGAP5 AGO1 ZFR TNKS LRRC8B ENO1 ENO2 ENO3	7.65e-06	475	211	13	31040226
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	PFKP GSTO2 CHUK BEND7 RRP12 ALOX5 KIF11 ZNF438 ZDHHC16 ITGA8 ADAM12 CFAP46	9.98e-06	415	211	12	16385451
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	INS SSPOP FBN1 FBN2 COL5A1 COL16A1 COL6A6 AGRN	1.25e-05	175	211	8	28071719
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 KIF26A TMEM94 KDM3B SLC8B1 PER2 SBF1 RRP12 TIGD3 NLRC5 ALOX5 NOTCH2 MTMR8 ARAP3 ADAMTS7 DIP2C LTBP3 NUP188 ANKRD33B AGRN	1.49e-05	1105	211	20	35748872
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 FBN2 JAG1	1.80e-05	9	211	3	12122015
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	JAG1 NOTCH2 DLL3	1.80e-05	9	211	3	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	JAG1 NOTCH2 DLL3	1.80e-05	9	211	3	16245338
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	FBN1 FBN2 COL5A1 COL16A1 COL6A6 MMRN2 AGRN	1.97e-05	135	211	7	28675934
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ATP6V0A1 CTTNBP2 INPP4A DAPK1 PFKP LUZP1 CSDE1 USP31 PHKB SBF1 SACS DNAH6 GPM6A DMXL2 OGT SYNE1 ZNFX1 ARHGAP5 AGO1 RIMS1 CTNND1 ABLIM2 ENO2	2.22e-05	1431	211	23	37142655
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	JAG1 NOTCH2 DLL3	2.56e-05	10	211	3	23665443
Pubmed	IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta.	IL17F CXCL2 CXCL3	2.56e-05	10	211	3	20042461
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	FBN2 TRAFD1 PIBF1 GPM6A CPT1B LUC7L2 ENO1 ENO3	2.94e-05	197	211	8	17500595
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 VPS33A USP31 USP36 DMXL2 USP46 RFWD3	3.40e-05	147	211	7	29576527
Pubmed	Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.	JAG1 NOTCH2 DLL3	3.50e-05	11	211	3	10878608
Pubmed	Defects in somite formation in lunatic fringe-deficient mice.	JAG1 NOTCH2 DLL3	3.50e-05	11	211	3	9690472
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	3.66e-05	2	211	2	30044367
Pubmed	Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.	FBN1 LTBP3	3.66e-05	2	211	2	26494287
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	3.66e-05	2	211	2	15131124
Pubmed	Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability.	ARHGAP5 CTNND1	3.66e-05	2	211	2	23653363
Pubmed	The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.	NLRP1 NLRP3	3.66e-05	2	211	2	26939933
Pubmed	E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.	SELE NLRP3	3.66e-05	2	211	2	37903858
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	3.66e-05	2	211	2	20404337
Pubmed	Fibrillin-1 and alpha8 integrin are co-expressed in the glomerulus and interact to convey adhesion of mesangial cells.	FBN1 ITGA8	3.66e-05	2	211	2	25482639
Pubmed	Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil.	NLRP1 NLRP3	3.66e-05	2	211	2	20370570
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	3.66e-05	2	211	2	8791520
Pubmed	NLRP1 and NLRP3 inflammasomes mediate LPS/ATP‑induced pyroptosis in knee osteoarthritis.	NLRP1 NLRP3	3.66e-05	2	211	2	29393464
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	3.66e-05	2	211	2	7744963
Pubmed	Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation.	PRSS12 AGRN	3.66e-05	2	211	2	17586728
Pubmed	A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.	JAG1 NOTCH2	3.66e-05	2	211	2	11861489
Pubmed	A 3'UTR SNP in NLRP3 gene is associated with susceptibility to HIV-1 infection.	NLRP1 NLRP3	3.66e-05	2	211	2	20502346
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	3.66e-05	2	211	2	26408953
Pubmed	Caspase-1 inflammasomes in infection and inflammation.	NLRP1 NLRP3	3.66e-05	2	211	2	17442855
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	3.66e-05	2	211	2	18006876
Pubmed	The Notch2-Jagged1 interaction mediates stem cell factor signaling in erythropoiesis.	JAG1 NOTCH2	3.66e-05	2	211	2	20829885
Pubmed	HUPO BPP pilot study: a proteomics analysis of the mouse brain of different developmental stages.	ENO1 ENO2	3.66e-05	2	211	2	17922513
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	3.66e-05	2	211	2	24484584
Pubmed	Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.	FBN1 LTBP3	3.66e-05	2	211	2	30306291
Pubmed	Characterization of the interaction between the human DNA topoisomerase IIbeta-binding protein 1 (TopBP1) and the cell division cycle 45 (Cdc45) protein.	CDC45 TOPBP1	3.66e-05	2	211	2	17887956
Pubmed	The role of NLRP1 and NLRP3 inflammasomes in the etiopathogeneses of pityriasis lichenoides chronica and mycosis fungoides: an immunohistochemical study.	NLRP1 NLRP3	3.66e-05	2	211	2	35776169
Pubmed	Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification.	JAG1 NOTCH2	3.66e-05	2	211	2	31343788
Pubmed	Protective role of p120-catenin on mitochondria by inhibiting NLRP3 in ventilator-induced lung injury.	NLRP3 CTNND1	3.66e-05	2	211	2	31507096
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	3.66e-05	2	211	2	12524050
Pubmed	Complete structure of the human gene encoding neuron-specific enolase.	ENO1 ENO2	3.66e-05	2	211	2	2045099
Pubmed	LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.	FBN1 LTBP3	3.66e-05	2	211	2	29625025
Pubmed	Rhinovirus-induced calcium flux triggers NLRP3 and NLRC5 activation in bronchial cells.	NLRC5 NLRP3	3.66e-05	2	211	2	23815151
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	3.66e-05	2	211	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	3.66e-05	2	211	2	35419902
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	3.66e-05	2	211	2	10504303
Pubmed	Isolation of murine neuron-specific and non-neuronal enolase cDNA clones.	ENO1 ENO2	3.66e-05	2	211	2	3801001
Pubmed	The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.	NLRP1 NLRP3	3.66e-05	2	211	2	25681332
Pubmed	Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus.	NLRP1 NLRP3	3.66e-05	2	211	2	24334646
Pubmed	Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration.	PRSS12 AGRN	3.66e-05	2	211	2	36609795
Pubmed	Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins.	ENO1 ENO3	3.66e-05	2	211	2	9169614
Pubmed	Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii.	NLRP1 NLRP3	3.66e-05	2	211	2	24549849
Pubmed	Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion.	CXCL2 CXCL3	3.66e-05	2	211	2	9277410
Pubmed	Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia.	PRSS12 AGRN	3.66e-05	2	211	2	21885656
Pubmed	Evaluation of the Genetic Association and Expressions of Notch-2 /Jagged-1 in Patients with Type 2 Diabetes Mellitus.	JAG1 NOTCH2	3.66e-05	2	211	2	34219868
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	3.66e-05	2	211	2	25524144
Pubmed	Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.	NLRP1 NLRP3	3.66e-05	2	211	2	24008734
Pubmed	The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.	PRSS12 AGRN	3.66e-05	2	211	2	27380275
Pubmed	Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage.	PRSS12 AGRN	3.66e-05	2	211	2	19303856
Pubmed	Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.	CA10 NRXN1	3.66e-05	2	211	2	28154140
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	3.66e-05	2	211	2	16407178
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	3.66e-05	2	211	2	10359653
Pubmed	Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.	JAG1 NOTCH2	3.66e-05	2	211	2	17366661
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	3.66e-05	2	211	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	3.66e-05	2	211	2	21851253
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	3.66e-05	2	211	2	21440062
Pubmed	Distribution of serum neuron-specific enolase and the establishment of a population reference interval in healthy adults.	ENO1 ENO2	3.66e-05	2	211	2	30779465
Pubmed	Association of NLRP1 and NLRP3 Polymorphisms with Psoriasis Vulgaris Risk in the Chinese Han Population.	NLRP1 NLRP3	3.66e-05	2	211	2	29850521
Pubmed	Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74.	CXCL2 CXCL3	3.66e-05	2	211	2	9873037
Pubmed	Differential expression of muscle-specific enolase in embryonic and fetal myogenic cells during mouse development.	ENO1 ENO3	3.66e-05	2	211	2	2090519
Pubmed	Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response.	NLRP1 NLRP3	3.66e-05	2	211	2	17164409
Pubmed	A genome-wide association study of copy-number variation identifies putative loci associated with osteoarthritis in Koreans.	CA10 TNKS	3.66e-05	2	211	2	25880085
Pubmed	Clinical features, outcomes, and genetic analysis in Korean children with Alagille syndrome.	JAG1 NOTCH2	3.66e-05	2	211	2	25676721
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	3.66e-05	2	211	2	8307578
Pubmed	Renal involvement and the role of Notch signalling in Alagille syndrome.	JAG1 NOTCH2	3.66e-05	2	211	2	23752887
Pubmed	Notch signaling regulates bile duct morphogenesis in mice.	JAG1 NOTCH2	3.66e-05	2	211	2	18365007
Pubmed	Inflammasomes: guardians of cytosolic sanctity.	NLRP1 NLRP3	3.66e-05	2	211	2	19120479
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	3.66e-05	2	211	2	24833718
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	3.66e-05	2	211	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	3.66e-05	2	211	2	20529844
Pubmed	Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein.	F9 LRP1	3.66e-05	2	211	2	12522212
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	3.66e-05	2	211	2	23133647
Pubmed	Sensing pathogens and danger signals by the inflammasome.	NLRP1 NLRP3	3.66e-05	2	211	2	19223160
Cytoband	10q24.1	RRP12 KIF11 ZDHHC16	1.38e-04	22	211	3	10q24.1
GeneFamily	Ubiquitin specific peptidases	USP34 USP9Y USP44 USP31 USP36 USP46	6.06e-06	56	147	6	366
GeneFamily	NLR family	NLRC5 NLRP5 NLRP1 NLRP3	4.65e-05	25	147	4	666
GeneFamily	Proteases, serine	TMPRSS11B PRSS46P PRSS12 TMPRSS2 CORIN	1.60e-04	63	147	5	738
GeneFamily	Ankyrin repeat domain containing	CTTNBP2 DAPK1 ANKRD34B NOTCH2 ANKRD30BL ARAP3 TNKS ANKRD33B	8.28e-04	242	147	8	403
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP5 NLRP1 NLRP3	1.06e-03	25	147	3	994
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM15 ADAM30 ADAM12	1.33e-03	27	147	3	47
GeneFamily	Nucleoporins	NUP205 RANBP2 NUP188	2.20e-03	32	147	3	1051
Coexpression	GSE29618_MONOCYTE_VS_MDC_UP	BACH1 BTG2 FBN2 UPP1 NOTCH2 DMXL2 IFFO1 CXCL2 NLRP3 LRP1 SORL1	6.96e-07	200	210	11	M4948
Coexpression	NABA_MATRISOME	SPAM1 INS ADAM15 SSPOP IL17F F9 FBN1 FBN2 CRISPLD1 COL5A1 COL16A1 COL6A6 PRSS12 ADAM30 ADAM12 CXCL2 CXCL3 LGALS8 TGM4 ADAMTS7 MMRN2 LTBP3 AGRN	6.84e-06	1008	210	23	MM17056
Coexpression	LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN	CENPF PFKP RRM1 NUP205 SACS KIF11 TOPBP1 GREB1 NUP188	7.42e-06	164	210	9	M13108
Coexpression	NABA_MATRISOME	SPAM1 INS ADAM15 SSPOP IL17F F9 FBN1 FBN2 CRISPLD1 COL5A1 COL16A1 COL6A6 PRSS12 ADAM30 ADAM12 CXCL2 CXCL3 LGALS8 TGM4 ADAMTS7 MMRN2 LTBP3 AGRN	9.10e-06	1026	210	23	M5889
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	USP34 INPP4A ITK LUZP1 CSDE1 BTG2 SACS NLRC5 KLRC2 NOTCH2 RALGDS RANBP2 OGT IFFO1 SYNE1 PARP8 DOCK10 NLRP1 ZNFX1 CD5 SENP6 ZFR TRAF3IP3 FBXL20 RNF139 ENO1 VPS13B SORL1	2.50e-05	1492	210	28	M40023
Coexpression	CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	BACH1 PFKP LUZP1 FBN1 SACS JAG1 MID1 UPP1 COL5A1 PRSS12 DOCK10 CXCL2 ARAP3 ANKRD33B	2.55e-05	465	210	14	M9192
Coexpression	GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	DCAF8 BACH1 SNX6 CCS PARP8 SENP6 LTBP3 VPS13B SORL1	3.33e-05	198	210	9	M7610
Coexpression	GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP	ITK UPP1 RALGDS SYNE1 MAP3K6 CD5 LTBP3 ENO2 ENO3	3.46e-05	199	210	9	M4430
Coexpression	GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN	USP34 BTG2 NOTCH2 RANBP2 IFFO1 SYNE1 LGALS8 RNF139 SORL1	3.60e-05	200	210	9	M8331
Coexpression	GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN	BACH1 NRXN1 ARHGAP29 UPP1 ICA1 DIP2C CTNND1 ENO2 ANKRD33B	3.60e-05	200	210	9	M7469
Coexpression	GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN	ACVRL1 CHUK JAG1 CCDC14 TOPBP1 ITGA8 USP46 SETDB2 UBA6	3.60e-05	200	210	9	M6039
Coexpression	GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN	USP34 RECQL5 ALOX5 CXCL2 CXCL3 ARHGAP5 RNASE4 ENO2 SORL1	3.60e-05	200	210	9	M5191
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL	CENPF NUP205 CDC45 SACS GPSM2 PCDH18 KIF11 TTF2 TOPBP1 NLRP1 RNF175 XRCC2 RFWD3 ADAMTS7 GREB1	5.77e-05	567	210	15	M45692
Coexpression	DODD_NASOPHARYNGEAL_CARCINOMA_UP	MKKS CENPF INPP4A URB2 RRM1 NUP205 CDC45 USP31 FBN1 NRXN1 SACS GPSM2 PCDH18 KIF11 CCDC14 COL5A1 TTF2 RANBP2 TOPBP1 DNAAF9 ADAM12 MTX2 LUC7L2 SENP6 ZFR ENO1	6.43e-05	1407	210	26	M14427
Coexpression	NABA_CORE_MATRISOME	SSPOP FBN1 FBN2 CRISPLD1 COL5A1 COL16A1 COL6A6 MMRN2 LTBP3 AGRN	6.93e-05	270	210	10	MM17057
Coexpression	NABA_CORE_MATRISOME	SSPOP FBN1 FBN2 CRISPLD1 COL5A1 COL16A1 COL6A6 MMRN2 LTBP3 AGRN	8.07e-05	275	210	10	M5884
Coexpression	MULLIGHAN_MLL_SIGNATURE_2_DN	USP34 DAPK1 LUZP1 RALGDS RANBP2 CXCL2 LRRC8B ZNF85 AGRN SORL1	9.09e-05	279	210	10	M16867
Coexpression	SOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_CORRELATED_WITH_AGE_1DY_POSITIVE	CACNA2D2 SYNE1 NLRP1 ENO2	9.32e-05	30	210	4	M41011
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 FBN2 JAG1 PKHD1 COL5A1 SYNE1 ANKRD33B	1.28e-08	176	211	10	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 JAG1 MID1 PKHD1 ARHGAP29 DNAH6 COL5A1	2.52e-08	189	211	10	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 BACH1 LUZP1 BTG2 PER2 COL5A1 RANBP2 COL16A1 ARHGAP5 SENP6	3.23e-08	194	211	10	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 PCDH18 COL5A1 COL16A1 COL6A6 PRSS12 SYNE1 ITGA8 LRP1	4.30e-08	200	211	10	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 DAPK1 CLSTN2 C8orf34 JAG1 PKHD1 ARHGAP29 COL5A1 SYNE1	1.79e-07	177	211	9	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CTTNBP2 ANKRD34B BEND7 PKHD1 GPM6A RNASE4 TMPRSS2 AGRN SLC6A14	2.27e-07	182	211	9	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CTTNBP2 ANKRD34B BEND7 PKHD1 GPM6A RNASE4 TMPRSS2 AGRN SLC6A14	2.27e-07	182	211	9	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 JAG1 MID1 PKHD1 ARHGAP29 COL5A1	2.49e-07	184	211	9	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Proliferative_Immature_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CACNA2D2 TLR6 F9 COL6A6 RIMS1 ENO2 ENO3 CFAP46	2.72e-07	135	211	8	ed0f94d3839eea3b60217c4352159ed481361f13
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 FBN2 PKHD1 ARHGAP29 SYNE1 ANKRD33B	2.98e-07	188	211	9	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ITK RRP12 USP36 RANBP2 OGT DOCK10 NLRP1 LUC7L SORL1	3.56e-07	192	211	9	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 PRSS12 SYNE1 ITGA8 LRP1	4.81e-07	199	211	9	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 PCDH18 COL5A1 COL16A1 COL6A6 PRSS12 SYNE1 ITGA8 LRP1	4.81e-07	199	211	9	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 USP9Y ITK NLRC5 OGT SYNE1 PARP8 LUC7L VPS13B	4.81e-07	199	211	9	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 DIP2C TRAF3IP3	5.02e-07	200	211	9	9156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 PRSS12 SYNE1 ITGA8 LRP1	5.02e-07	200	211	9	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 DIP2C TRAF3IP3	5.02e-07	200	211	9	566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 PRSS12 SYNE1 ITGA8 LRP1	5.02e-07	200	211	9	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	INPP4A FTCD USP9Y FBN2 ENO2 ENO3 SLC6A14 SORL1	8.20e-07	156	211	8	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TLR6 UPP1 DMXL2 CXCL2 CXCL3 NLRP3 ANKRD33B SORL1	8.60e-07	157	211	8	5098675f64342c41c5ca3551b24962d10c83e64d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 CACNA2D2 TDRD6 ALOX5 PRSS12 DOCK10 ADAM12 SLC8A3	1.04e-06	161	211	8	c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR6 ITGA7 ITK KLRC2 ALOX5 DMXL2 ADAM12 NLRP3	1.25e-06	165	211	8	651d40eadb1b34de618af94c167f43635729d43f
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA2D2 CA10 IL17F ITK SYNE1 ADAM12 CORIN TRAF3IP3	1.31e-06	166	211	8	bb93db4613c067c56614ab1ca39e73ee46484387
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA2D2 CA10 IL17F ITK SYNE1 ADAM12 CORIN TRAF3IP3	1.31e-06	166	211	8	c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FBN2 JAG1 CRISPLD1 CXCL2 CXCL3 ARAP3 MMRN2 LTBP3	2.03e-06	176	211	8	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 JAG1 PKHD1 ARHGAP29 COL5A1	2.21e-06	178	211	8	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	Adult-Immune-T_lymphocyte-D122\|Adult / Lineage, Cell type, age group and donor	USP9Y ITK NLRC5 KLRC2 PARP8 DOCK10 NLRP1 TRAF3IP3	2.40e-06	180	211	8	06c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 JAG1 PKHD1 ARHGAP29 ANKRD33B	2.50e-06	181	211	8	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 FBN2 PKHD1 COL5A1 ANKRD33B	2.50e-06	181	211	8	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 JAG1 PKHD1 ARHGAP29 ANKRD33B	2.71e-06	183	211	8	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 DAPK1 C8orf34 FBN2 PKHD1 ARHGAP29 ANKRD33B	2.71e-06	183	211	8	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM15 ACVRL1 CDC45 ARHGAP29 SELE ATP8B3 ARAP3 MMRN2	2.82e-06	184	211	8	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ITK SLC8B1 TTF2 DOCK10 ARHGAP5 TRAF3IP3 ENO2 SORL1	2.82e-06	184	211	8	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS ITGA7 MID1 NRIP2 ITGA8 RNASE4 LRP1 GREB1	2.82e-06	184	211	8	c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A FBN1 JAG1 KLK9 CRISPLD1 MAP3K6 MMRN2 RIMS1	2.94e-06	185	211	8	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	INPP4A ITK NLRC5 KLRC2 PARP8 DOCK10 TRAF3IP3 SORL1	2.94e-06	185	211	8	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	10x5'-Lung-Mast\|Lung / Manually curated celltypes from each tissue	CTTNBP2 ARHGAP29 BEGAIN PRSS12 ADAM12 SLC8A3 ADAMTS7 DIP2C	3.18e-06	187	211	8	f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell	10x5'-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	CTTNBP2 ARHGAP29 BEGAIN PRSS12 ADAM12 SLC8A3 ADAMTS7 DIP2C	3.18e-06	187	211	8	da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 CLSTN2 FBN2 ARHGAP29 KLK5 SYNE1 ANKRD33B AGRN	3.31e-06	188	211	8	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 CLSTN2 FBN2 ARHGAP29 KLK5 SYNE1 ANKRD33B AGRN	3.31e-06	188	211	8	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTTNBP2 KIF26A ADAM15 ACVRL1 FBN1 JAG1 ARAP3 MMRN2	3.44e-06	189	211	8	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF26A ADAM15 ACVRL1 FBN1 JAG1 NLRP1 ARAP3 MMRN2	3.44e-06	189	211	8	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	INPP4A ITK OGT PARP8 DOCK10 CD5 TRAF3IP3 SORL1	3.44e-06	189	211	8	e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTTNBP2 BTG2 ALOX5 BEGAIN RANBP2 ADAM12 SLC8A3 ADAMTS7	3.44e-06	189	211	8	f01158bb15df3117fae1271bf8cf8c2501422671
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF26A ADAM15 ACVRL1 JAG1 UPP1 CRISPLD1 ARAP3 MMRN2	3.44e-06	189	211	8	feedac2751ed770f80bc56fec31662b5b3826f58
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITK NLRC5 PARP8 DOCK10 NLRP1 CD5 TRAF3IP3 SORL1	3.72e-06	191	211	8	d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITK NLRC5 PARP8 DOCK10 NLRP1 CD5 TRAF3IP3 SORL1	3.72e-06	191	211	8	9aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLSTN2 FBN1 PCDH18 COL5A1 COL16A1 ITGA8 ADAM12 LRP1	3.72e-06	191	211	8	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITK NLRC5 PARP8 DOCK10 NLRP1 CD5 TRAF3IP3 SORL1	3.72e-06	191	211	8	b42c54308abe1241cc38ddce96b9d38d07983891
ToppCell	EC\|World / Lineage and Cell class	KIF26A ADAM15 ACVRL1 JAG1 UPP1 SELE GPM6A MMRN2	3.87e-06	192	211	8	478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLSTN2 FBN1 PCDH18 COL5A1 COL16A1 ITGA8 ADAM12 LRP1	3.87e-06	192	211	8	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLSTN2 FBN1 PCDH18 COL5A1 COL16A1 ITGA8 ADAM12 LRP1	3.87e-06	192	211	8	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 PRSS12 ITGA8 LRP1	3.87e-06	192	211	8	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRK2 DAPK1 ALOX5 DMXL2 CXCL2 CXCL3 NLRP3 LRP1	4.02e-06	193	211	8	45205ad1ef12aabf33059a7ff922a3bb86994c2f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRK2 DAPK1 ALOX5 DMXL2 CXCL2 CXCL3 NLRP3 LRP1	4.02e-06	193	211	8	1beca3d3b34082b7d9112fbd094bee8019921ca0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LRRK2 C8orf34 JAG1 PKHD1 ARHGAP29 COL5A1 SYNE1	4.02e-06	193	211	8	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	Adult-Immune-T_lymphocyte\|Adult / Lineage, Cell type, age group and donor	ITK NLRC5 PARP8 DOCK10 NLRP1 ADAM12 CD5 TRAF3IP3	4.02e-06	193	211	8	26df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRK2 DAPK1 ALOX5 DMXL2 CXCL2 CXCL3 NLRP3 LRP1	4.02e-06	193	211	8	2ebb950476767f330241b0077ced22e55e124359
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF FBN1 FBN2 ARHGAP29 GPSM2 DNMT3L COL5A1 COL16A1	4.18e-06	194	211	8	775600880bb77781de48085d8744c1030223de1f
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADAM15 OXGR1 ACVRL1 ARHGAP29 ITGA8 ADAMTS7 MMRN2 AGRN	4.18e-06	194	211	8	8a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF FBN1 FBN2 ARHGAP29 GPSM2 DNMT3L COL5A1 COL16A1	4.18e-06	194	211	8	04ecb609d233a4b12e275c604810937830363e17
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	4.18e-06	194	211	8	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 ACVRL1 FBN1 JAG1 GPM6A NLRP1 ARAP3 MMRN2	4.18e-06	194	211	8	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO7B KIF26A ADAM15 ACVRL1 CDC45 JAG1 MMRN2 ANKRD33B	4.34e-06	195	211	8	517af3e6784f02c382df6f5691945eefaa9ec4ae
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LRRK2 FBN2 UPP1 DMXL2 CXCL2 CXCL3 NLRP3 LRP1	4.34e-06	195	211	8	580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA2D2 LRRK2 C8orf34 GPM6A SYNE1 TMPRSS2 ROS1 CTNND1	4.34e-06	195	211	8	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	BACH1 UPP1 ALOX5 ZNF438 DMXL2 DOCK10 CXCL3 LRP1	4.34e-06	195	211	8	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INS FBN1 BTG2 NOTCH2 COL5A1 COL16A1 RNASE4 LTBP3	4.34e-06	195	211	8	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAM15 ABHD6 ACVRL1 USP31 BEND7 ARHGAP29 ICA1 MMRN2	4.51e-06	196	211	8	29ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS FBN1 GPM6A COL5A1 COL16A1 RNASE4 LRP1 LTBP3	4.51e-06	196	211	8	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS FBN1 GPM6A COL5A1 COL16A1 RNASE4 LRP1 LTBP3	4.51e-06	196	211	8	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 DIP2C	4.68e-06	197	211	8	bed8a9b73af5caee51b1232b31c24a59353658df
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_CTL\|Influenza_Severe / Disease, condition lineage and cell class	ADM2 ITK USP44 CCDC78 USP46 TGM4 CD5 ENO2	4.68e-06	197	211	8	8610307434d99e6411a5a6c6769094e9a0749d4d
ToppCell	Mild_COVID-19-T/NK-CD4+_T_1\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CA10 IL17F ITK SYNE1 PARP8 ADAM12 CD5 TRAF3IP3	4.68e-06	197	211	8	98fca0a2e2f66525c5c9d6cdaebcad14b4d53da4
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	C8orf34 FBN1 COL5A1 COL6A6 SYNE1 ITGA8 LRP1 ANKRD33B	4.68e-06	197	211	8	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_1-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CA10 IL17F ITK SYNE1 PARP8 ADAM12 CD5 TRAF3IP3	4.68e-06	197	211	8	b4f801cd48955463285e0c1bb4fc8ea790c631cb
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLSTN2 C8orf34 C6orf118 CCDC78 DNAH6 PRSS12 SYNE1 CFAP46	4.68e-06	197	211	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 DIP2C	4.68e-06	197	211	8	b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_1\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CA10 IL17F ITK SYNE1 PARP8 ADAM12 CD5 TRAF3IP3	4.68e-06	197	211	8	821c1df511cc4a286ddc6fa229059561f6f6bade
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 TRAF3IP3	4.85e-06	198	211	8	cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 ALOX5 BEGAIN DOCK10 ADAM12 SLC8A3 ADAMTS7 TRAF3IP3	4.85e-06	198	211	8	d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCell	Non-neuronal-Postmitotic-Mural\|World / Primary Cells by Cluster	ACVRL1 ARHGAP29 PCDH18 SELE CXCL2 CXCL3 MMRN2 AGRN	4.85e-06	198	211	8	dd38840a96171f58da243daa22b013e15a81db4a
ToppCell	Non-neuronal-Postmitotic-Mural-Mural\|World / Primary Cells by Cluster	ACVRL1 ARHGAP29 PCDH18 SELE CXCL2 CXCL3 MMRN2 AGRN	4.85e-06	198	211	8	9fc1035ea447a4551a66944c869c4671e17cec61
ToppCell	Non-neuronal-Postmitotic-Mural-Mural-18\|World / Primary Cells by Cluster	ACVRL1 ARHGAP29 PCDH18 SELE CXCL2 CXCL3 MMRN2 AGRN	4.85e-06	198	211	8	21efb7bcd24f24d20791b34e75d6f9d46a129481
ToppCell	mild-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATP6V0A1 BACH1 LRRK2 ALOX5 DMXL2 CXCL3 NLRP3 LRP1	5.04e-06	199	211	8	d0d286eafe935f9b3aaba5b783e8911251121b4a
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 PRSS12 ITGA8 LRP1	5.04e-06	199	211	8	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLSTN2 FBN1 FBN2 PCDH18 COL5A1 ITGA8 ADAMTS7 LRP1	5.04e-06	199	211	8	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PFKP ITGA7 UPP1 MAP3K6 RNASE4 LRP1 LTBP3 ENO2	5.04e-06	199	211	8	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FBN1 CRISPLD1 PCDH18 COL5A1 PRSS12 SYNE1 LRP1 LTBP3	5.04e-06	199	211	8	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CA10 ITK NLRC5 PARP8 DOCK10 ADAM12 CD5 TRAF3IP3	5.04e-06	199	211	8	fbdde57dd88656621801e65ee2818251588f3874
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 CRISPLD1 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABHD6 ACVRL1 MID1 ARHGAP29 SELE GPM6A MMRN2 CTNND1	5.23e-06	200	211	8	ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 PCDH18 COL5A1 COL16A1 COL6A6 ITGA8 LRP1	5.23e-06	200	211	8	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CTTNBP2 ADAM15 ACVRL1 LUZP1 FBN1 JAG1 ARAP3 MMRN2	5.23e-06	200	211	8	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 GPSM2 COL5A1 COL16A1 COL6A6 SYNE1 ITGA8 LRP1	5.23e-06	200	211	8	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	facs-Marrow-B-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK5 WDR72 ADAM12 CXCL2 AK8 ROS1 RIMS1	5.50e-06	143	211	7	6df16bf0324661cd9707df69cb39f4b5498d6d49
Computational	Nucleotide metabolism.	CENPF RRM1 NUP205 CDC45 ALMS1 GPSM2	1.28e-04	64	132	6	MODULE_337
Computational	Genes in the cancer module 125.	CENPF RRM1 CDC45 TOPBP1 LIG4	1.91e-04	44	132	5	MODULE_125
Drug	N-succinylphenylglycine	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID000448582
Drug	AC1MOUJL	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID003400924
Drug	C03356	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID000439988
Drug	3-bromo-2-(bromomethyl)propionic acid	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID000318915
Drug	C04309	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID000440293
Drug	2,3-diketo-1-phosphohexane	ENO1 ENO2 ENO3	7.63e-07	3	209	3	CID000192519
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	PIGN USP34 CACNA2D2 EXD3 ALMS1 KLK5 USP36 OGT XRCC2 ZFR GREB1	1.81e-06	193	209	11	3258_DN
Drug	dimethyl chlorophosphate	ENO1 ENO2 ENO3	3.03e-06	4	209	3	CID000101863
Drug	[2-(oxidoamino)-2-oxoethyl]phosphonic acid	ENO1 ENO2 ENO3	3.03e-06	4	209	3	CID011969443
Drug	3-aminoenolpyruvate-2-phosphate	ENO1 ENO2 ENO3	3.03e-06	4	209	3	CID003037152
Drug	2-ptz	ENO1 ENO2 ENO3	3.03e-06	4	209	3	CID000445375
Drug	tricyclohexylammonium	ENO1 ENO2 ENO3	3.03e-06	4	209	3	CID000226271
Drug	hexammineruthenium	F9 CSDE1 NLRP1 NLRP3 ENO3	6.17e-06	29	209	5	CID000124002
Drug	Hecameg	ABHD6 ENO1 ENO2 ENO3	6.43e-06	14	209	4	CID002733955
Drug	N-methylacrylamide	ENO1 ENO2 ENO3	7.52e-06	5	209	3	CID000014471
Drug	AC1L1CAI	ENO1 ENO2 ENO3	7.52e-06	5	209	3	CID000000145
Drug	tartronate semialdehyde phosphate	ENO1 ENO2 ENO3	7.52e-06	5	209	3	CID000151938
Drug	2-phospho-3-butenoic acid	ENO1 ENO2 ENO3	7.52e-06	5	209	3	CID000191423
Drug	1-Pdmsp	ENO1 ENO2 ENO3	7.52e-06	5	209	3	CID000000561
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	PHKB BTG2 SLC8B1 JAG1 RECQL5 CPT1B LGALS8 TNKS SLC6A14 SORL1	8.18e-06	184	209	10	1081_UP
Drug	Gut factor	INS FBN2 GPSM2 CPT1B	8.70e-06	15	209	4	CID000123786
Drug	AC1NUV1C	INS RRM1 FBN2 TTF2 XRCC2 ENO1	8.92e-06	53	209	6	CID005494394
Drug	Freon 22	NLRP3 ENO1 ENO2 ENO3	1.15e-05	16	209	4	CID000006372
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A	INPP4A ITGA7 EXD3 PER2 IFFO1 DOCK10 CXCL2 CXCL3 LGALS8 ENO3	1.30e-05	194	209	10	3826_DN
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A	USP34 DCAF8 INPP4A ABHD6 SLC8B1 SBF1 JAG1 PADI1 USP36 GREB1	1.49e-05	197	209	10	6768_DN
Drug	dimidium	ENO1 ENO2 ENO3	1.49e-05	6	209	3	CID000068207
Drug	Z(2-Cl)-OSu	ENO1 ENO2 ENO3	1.49e-05	6	209	3	CID000580665
Drug	4-(N,N-dimethylamino)cinnamoyl-CoA	ENO1 ENO2 ENO3	1.49e-05	6	209	3	CID000445461
Drug	s-BuLi	MID1 UPP1 SYNE1 ENO1	1.50e-05	17	209	4	CID000061028
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; PC3; HT_HG-U133A	SPAM1 CACNA2D2 CENPF VPS33A FBN2 GPSM2 SYNE1 CPT1B ADAM12 TMPRSS2	1.55e-05	198	209	10	6681_DN
Drug	LY-171,883; Up 200; 1uM; MCF7; HG-U133A	INPP4A ADM2 BACH1 ACVRL1 SLC8B1 OGT IFFO1 ADAM12 LGALS8 ARAP3	1.62e-05	199	209	10	222_UP
Drug	2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A	ATP6V0A1 LUZP1 RRP12 RECQL5 PADI1 CD5 LUC7L2 SENP6 ZFR AGRN	1.62e-05	199	209	10	346_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	CACNA2D2 INPP4A ABHD6 LUZP1 PHKB EXD3 SBF1 MID1 KLK5 ALOX5	1.69e-05	200	209	10	6963_UP
Drug	N-acetylserine	NLRP1 TGM4 ENO1 ENO2 ENO3	1.86e-05	36	209	5	CID000065249
Drug	N-tert-butylacrylamide	ENO1 ENO2 ENO3	2.60e-05	7	209	3	CID000007877
Drug	glycidol phosphate	ENO1 ENO2 ENO3	2.60e-05	7	209	3	CID000152659
Drug	lavendustin C6	ENO1 ENO2 ENO3	2.60e-05	7	209	3	CID000126839
Drug	CPEP	ENO1 ENO2 ENO3	2.60e-05	7	209	3	CID000360637
Drug	citric acid	INS PFKP GSTO2 RRM1 F9 KLK5 CPT1B RNASE4 RNH1 DLL3 ENO1 ENO2 ENO3	2.81e-05	357	209	13	CID000000311
Drug	enoxacin	RRM1 ENO1 ENO2 ENO3	2.98e-05	20	209	4	CID000003229
Drug	(2s,5s)-5-Carboxymethylproline	ACVRL1 ITGA7 F9 FBN1 SELE COL5A1 COL16A1 ITGA8 CD5 DLL3 ENO1 SLC2A12	3.59e-05	314	209	12	CID000447989
Drug	hexane	INS ABHD6 CLSTN2 MID1 ALOX5 GREB1	3.79e-05	68	209	6	CID000008058
Drug	macrophomate	ENO1 ENO2 ENO3	4.13e-05	8	209	3	CID010889109
Drug	ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A	VPS33A URB2 ALMS1 JAG1 XRCC2 CPT1B GREB1 ENO2 SLC6A14	5.56e-05	185	209	9	5235_DN
Drug	AC1L19IJ	ENO1 ENO2 ENO3	6.15e-05	9	209	3	CID000000562
Drug	AC1L1A4W	ENO1 ENO2 ENO3	6.15e-05	9	209	3	CID000000837
Drug	Econazole nitrate [24169-02-6]; Up 200; 9uM; MCF7; HT_HG-U133A	CACNA2D2 DAPK1 ALMS1 SBF1 JAG1 RECQL5 PARP8 RNASE4 ENO3	7.11e-05	191	209	9	6008_UP
Drug	retinoic acid; Up 200; 1uM; MCF7; HG-U133A	INPP4A ADM2 ACVRL1 LUZP1 BTG2 SLC8B1 IFFO1 RNASE4 TMPRSS2	7.11e-05	191	209	9	224_UP
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	BACH1 ALMS1 NOTCH2 COL5A1 USP46 UBA6 LRRC8B VPS13B SORL1	7.11e-05	191	209	9	4168_DN
Drug	phenylthiocarbamide	PFKP RRM1 F9 TAS2R10 RIMS1 ENO1	7.13e-05	76	209	6	CID000676454
Drug	clozapine; Down 200; 10uM; HL60; HT_HG-U133A	SPAM1 CENPF TRAFD1 RALGDS PRSS12 USP46 CXCL2 LRRC8B NUP188	7.40e-05	192	209	9	6188_DN
Drug	Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A	SPAM1 CLSTN2 BTG2 SBF1 PADI1 USP36 COL5A1 IFFO1 AGRN	8.01e-05	194	209	9	7051_UP
Drug	AC1L2RD2	ABHD6 CCS	8.39e-05	2	209	2	CID000101697
Drug	Brn 0611686	CLSTN2 FBN1	8.39e-05	2	209	2	CID000080163
Drug	AC1NDSSF	PFKP FBN2	8.39e-05	2	209	2	CID004631017
Drug	funiferine N-oxide	ATP6V0A1 FBN1 FBN2 LTBP3 AGRN	8.53e-05	49	209	5	CID000191631
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; HL60; HG-U133A	FBN2 SLC8B1 ALMS1 BEGAIN ICA1 ADAM12 TMPRSS2 CTNND1 AGRN	8.67e-05	196	209	9	1418_UP
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A	PIGN ATP6V0A1 DCAF8 ALMS1 RECQL5 USP36 XRCC2 GREB1 VPS13B	8.67e-05	196	209	9	3473_UP
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A	USP34 RRM1 FBN2 SBF1 DOCK10 MAP3K6 SENP6 TNKS ENO1	8.67e-05	196	209	9	6568_UP
Drug	pyrene-4,5-dione	ENO1 ENO2 ENO3	8.73e-05	10	209	3	CID000160814
Drug	HBF4	CLSTN2 ACVRL1 SYNE1	8.73e-05	10	209	3	CID000028118
Drug	L-fuconic acid	ENO1 ENO2 ENO3	8.73e-05	10	209	3	CID000345732
Drug	phosphoenolthiopyruvate	ENO1 ENO2 ENO3	8.73e-05	10	209	3	CID000194910
Drug	xylonate	ENO1 ENO2 ENO3	8.73e-05	10	209	3	CID000010264
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	PIGN DCAF8 INPP4A SBF1 USP36 COL5A1 XRCC2 TMPRSS2 GREB1	9.01e-05	197	209	9	3467_UP
Drug	FK-506; Up 200; 1uM; MCF7; HG-U133A	ATP6V0A1 LUZP1 TRAFD1 SBF1 RRP12 COL5A1 TMPRSS2 NUP188 AGRN	9.01e-05	197	209	9	284_UP
Drug	estradiol, USP; Up 200; 0.01uM; HL60; HG-U133A	SPAM1 LUZP1 BTG2 RRP12 DOCK10 LUC7L CD5 LRP1 DIP2C	9.01e-05	197	209	9	387_UP
Drug	Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A	INPP4A ITGA7 JAG1 NOTCH2 DOCK10 LGALS8 RNASE4 UBA6 SENP6	9.01e-05	197	209	9	3797_DN
Drug	6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A	PIGN DAPK1 CLSTN2 URB2 MID1 SYNE1 ICA1 ADAM12 TMPRSS2	9.01e-05	197	209	9	6813_UP
Drug	rofecoxib; Down 200; 10uM; MCF7; HG-U133A	DCAF8 ABHD6 SLC8B1 TRAFD1 MID1 OGT IFFO1 PARP8 ENO2	9.01e-05	197	209	9	256_DN
Drug	Meglumine [6284-40-8]; Down 200; 20.4uM; MCF7; HT_HG-U133A	ADAM15 VPS33A ABHD6 JAG1 CCS USP36 OGT CPT1B LGALS8	9.01e-05	197	209	9	5285_DN
Drug	Delsoline [509-18-2]; Up 200; 8.6uM; HL60; HT_HG-U133A	BACH1 JAG1 RECQL5 MID1 COL5A1 NLRP1 CD5 LRP1 TMPRSS2	9.01e-05	197	209	9	2513_UP
Drug	gentamicin	INS ITGA7 SLC26A1 F9 JAG1 ALOX5 TGM4 LRP1 VPS13B	9.37e-05	198	209	9	CID000003467
Drug	Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A	ABHD6 URB2 FBN1 BTG2 MID1 DMXL2 PARP8 LIG4 TRAF3IP3	9.37e-05	198	209	9	4706_UP
Drug	Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A	PIGN USP34 SPAM1 ATP6V0A1 CACNA2D2 RRP12 UPP1 RALGDS COL16A1	9.73e-05	199	209	9	3449_UP
Drug	2,4,4'-trichlorobiphenyl	CENPF INPP4A ADM2 DAPK1 URB2 PFKP RRM1 NUP205 USP44 USP31 SLC8B1 SACS BEND7 TDRD6 DNMT3L WDR72 NLRP5 TTF2 OGT TOPBP1 ADAM12 RFWD3 ADAMTS7 TMPRSS2 RIMS1 GREB1 CTNND1 ENO2	9.93e-05	1411	209	28	ctd:C081766
Drug	Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A	PIGN SPAM1 CACNA2D2 SLC8B1 MID1 KLK5 PADI1 SENP6 TMPRSS2	1.01e-04	200	209	9	7030_UP
Drug	NSC243805	ACVRL1 KLK5 ALOX5 COL5A1	1.03e-04	27	209	4	CID000316274
Drug	Thimerosal	USP34 PFKP CA10 LUZP1 PHKB EXD3 FBN1 MID1 UPP1 TDRD6 ALOX5 ATP8B3 FAM76B MAP3K6 ARHGAP5 RNASE4 AGO1 ARAP3 RBAK RIMS1 ENO1 SLC2A12 ENO2 ENO3 SORL1	1.13e-04	1199	209	25	ctd:D013849
Drug	C acid	INS ACVRL1 ALOX5 SYNE1	1.37e-04	29	209	4	CID000008563
Drug	tetrahydroaldosterone-3-glucuronide	LRP1 ENO1 ENO2 ENO3	1.37e-04	29	209	4	CID000167918
Drug	SNAC	INS F9 NLRP1 MTTP	1.37e-04	29	209	4	CID000158789
Drug	2,4,5,2',5'-pentachlorobiphenyl	CENPF INPP4A ADM2 DAPK1 URB2 PFKP RRM1 NUP205 USP44 USP31 SLC8B1 SACS BEND7 TDRD6 DNMT3L WDR72 NLRP5 TTF2 OGT TOPBP1 ADAM12 RFWD3 ADAMTS7 TMPRSS2 RIMS1 GREB1 CTNND1 ENO2	1.42e-04	1441	209	28	ctd:C009828
Drug	ent-kaurene	CTTNBP2 CHUK RANBP2 NLRP3	1.57e-04	30	209	4	CID000440911
Drug	LG61	ENO1 ENO2 ENO3	1.58e-04	12	209	3	CID000520177
Drug	AC1L18ZV	ENO1 ENO2 ENO3	1.58e-04	12	209	3	CID000000329
Drug	methyl triflate	MID1 SYNE1 RNH1	1.58e-04	12	209	3	CID000009526
Drug	AC1MO08Q	CLSTN2 RRM1 RALGDS NLRP1	1.79e-04	31	209	4	CID003336188
Drug	Magnetite Nanoparticles	USP34 ZNF765 CHUK BTG2 PER2 SACS JAG1 MID1 UPP1 KIF11 DNMT3L COL5A1 TOPBP1 DOCK10 FAM76B CXCL2 CXCL3 NLRP3 LIG4 RNASE4 ARAP3 LUC7L2 LRP1 ZFR ENO2 SORL1	1.79e-04	1310	209	26	ctd:D058185
Drug	lithium aluminum hydride	ATP6V0A1 INS ACVRL1 F9 SLC8B1 KLK9 KLK5 SYNE1 RNH1 RORB AGRN	1.93e-04	320	209	11	CID000028112
Drug	m1 C	SYNE1 ENO1 ENO2 ENO3	2.03e-04	32	209	4	CID000448219
Drug	butandiol	INS CXCL2 DLL3 ENO3	2.03e-04	32	209	4	CID000165788
Drug	1q1m	RRM1 ALOX5 SYNE1 MTTP	2.03e-04	32	209	4	CID000447994
Drug	losartan	INS ACVRL1 ITGA7 FBN1 FBN2 SELE COL5A1 COL16A1 ITGA8 TGM4 RNASE4 ZFR	2.07e-04	378	209	12	CID000003961
Drug	PPCM	ABHD6 CLSTN2 ENO1 ENO2 ENO3	2.08e-04	59	209	5	CID000001292
Disease	Malignant neoplasm of breast	CENPF PHKB PER2 JAG1 BEND7 ARHGAP29 NLRC5 NOTCH2 ZNF438 SYNE1 MTMR8 XRCC2 ADAM12 MAP3K6 CXCL2 CXCL3 SLC8A3 ARAP3 DIP2C ENO1 VPS13B SORL1	4.65e-06	1074	201	22	C0006142
Disease	Familial thoracic aortic aneurysm and aortic dissection	ACVRL1 FBN1 FBN2 JAG1 COL5A1	3.07e-05	53	201	5	C4707243
Disease	Hepatic ductular hypoplasia	JAG1 NOTCH2	4.62e-05	2	201	2	C2930797
Disease	Calcium oxalate urolithiasis	OXGR1 SLC26A1	4.62e-05	2	201	2	cv:C1833683
Disease	Alagille syndrome (is_implicated_in)	JAG1 NOTCH2	4.62e-05	2	201	2	DOID:9245 (is_implicated_in)
Disease	Alagille Syndrome 2	JAG1 NOTCH2	4.62e-05	2	201	2	C1857761
Disease	Alagille Syndrome 1	JAG1 NOTCH2	4.62e-05	2	201	2	C1956125
Disease	Alagille Syndrome	JAG1 NOTCH2	4.62e-05	2	201	2	C0085280
Disease	Arteriohepatic dysplasia	JAG1 NOTCH2	4.62e-05	2	201	2	cv:C0085280
Disease	Colorectal Carcinoma	CLSTN2 C8orf34 FBN2 SACS PKHD1 RALGDS SYNE1 PARP8 ARAP3 PUS10 LRP1 MMRN2 DIP2C TRAF3IP3 SORL1	1.02e-04	702	201	15	C0009402
Disease	viral pneumonia (biomarker_via_orthology)	CXCL2 CXCL3	1.38e-04	3	201	2	DOID:10533 (biomarker_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	1.38e-04	3	201	2	DOID:65 (implicated_via_orthology)
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	2.75e-04	4	201	2	DOID:0060249 (is_implicated_in)
Disease	Global developmental delay	CACNA2D2 TMEM94 KDM3B CSDE1 PIBF1 AGO1	3.10e-04	133	201	6	C0557874
Disease	Geleophysic dysplasia	FBN1 LTBP3	4.56e-04	5	201	2	C3489726
Disease	Acromicric Dysplasia	FBN1 LTBP3	4.56e-04	5	201	2	C0265287
Disease	calcium oxalate nephrolithiasis (is_implicated_in)	OXGR1 SLC26A1	4.56e-04	5	201	2	DOID:0080652 (is_implicated_in)
Disease	aspiration pneumonia (biomarker_via_orthology)	CXCL2 CXCL3	6.80e-04	6	201	2	DOID:0050152 (biomarker_via_orthology)
Disease	esophageal cancer (biomarker_via_orthology)	CXCL2 CXCL3	6.80e-04	6	201	2	DOID:5041 (biomarker_via_orthology)
Disease	kallikrein-8 measurement	KLK9 KLK5	6.80e-04	6	201	2	EFO_0020516
Disease	acute necrotizing pancreatitis (biomarker_via_orthology)	BTG2 CXCL2 CXCL3	7.21e-04	26	201	3	DOID:0080998 (biomarker_via_orthology)
Disease	diabetes mellitus (implicated_via_orthology)	OGT ICA1 LRP1	7.21e-04	26	201	3	DOID:9351 (implicated_via_orthology)
Disease	eye morphology measurement	ADAM15 PFKP CA10 LUZP1 ZNF438 COL5A1 MTX2	7.71e-04	218	201	7	EFO_0007858
Disease	Bleeding tendency	ACVRL1 COL5A1	9.48e-04	7	201	2	C1458140
Disease	spontaneous coronary artery dissection	FBN1 FAM76B LRP1	1.22e-03	31	201	3	EFO_0010820
Disease	vitamin D-dependent rickets (implicated_via_orthology)	CXCL2 CXCL3	1.26e-03	8	201	2	DOID:0080883 (implicated_via_orthology)
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	FBN1 ITGA8	1.26e-03	8	201	2	DOID:4783 (biomarker_via_orthology)
Disease	severe acute respiratory syndrome (biomarker_via_orthology)	CXCL2 CXCL3	1.26e-03	8	201	2	DOID:2945 (biomarker_via_orthology)
Disease	triacylglycerol 58:10 measurement	C8orf34 NRXN1 USP46	1.59e-03	34	201	3	EFO_0010437
Disease	Sarcomatoid Renal Cell Carcinoma	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	1.88e-03	128	201	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	1.88e-03	128	201	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	1.88e-03	128	201	5	C1266044
Disease	Papillary Renal Cell Carcinoma	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	1.88e-03	128	201	5	C1306837
Disease	Renal Cell Carcinoma	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	1.88e-03	128	201	5	C0007134
Disease	macula measurement	FBN1 C6orf118 WDR72 FAM76B RORB SORL1	1.93e-03	189	201	6	EFO_0008375
Disease	Bone Diseases	JAG1 LTBP3	2.00e-03	10	201	2	C0005940
Disease	aortic aneurysm	FBN1 LRP1	2.00e-03	10	201	2	EFO_0001666
Disease	vitamin D measurement, parental genotype effect measurement	C8orf34 TEKT5	2.00e-03	10	201	2	EFO_0004631, EFO_0005939
Disease	pneumonia (biomarker_via_orthology)	CXCL2 CXCL3	2.44e-03	11	201	2	DOID:552 (biomarker_via_orthology)
Disease	intraocular pressure measurement	CTTNBP2 FBN1 FBN2 PKHD1 COL5A1 TTF2 COL16A1 ICA1 ADAM12 LTBP3	2.71e-03	509	201	10	EFO_0004695
Disease	bronchopulmonary dysplasia (biomarker_via_orthology)	CXCL2 CXCL3	2.91e-03	12	201	2	DOID:11650 (biomarker_via_orthology)
Disease	prostatitis (biomarker_via_orthology)	CXCL2 CXCL3	2.91e-03	12	201	2	DOID:14654 (biomarker_via_orthology)
Disease	hyperinsulinism (is_implicated_in)	INS MTTP	2.91e-03	12	201	2	DOID:2018 (is_implicated_in)
Disease	chronotype measurement	USP34 CACNA2D2 CA10 USP31 EXD3 C6orf118 PER2 NRXN1 PKHD1 BEGAIN WDR72 FAM76B DIP2C RIMS1	3.03e-03	882	201	14	EFO_0008328
Disease	depressive symptom measurement, response to antidepressant	DCAF12L2 NLRP1 TGM4 DIP2C	3.12e-03	88	201	4	EFO_0007006, GO_0036276
Disease	descending aortic diameter	FBN1 CRISPLD1 ADAMTS7 LRP1	3.12e-03	88	201	4	EFO_0021788
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	ZNF765 LRRK2 DAPK1 ALOX5 RNF139	3.51e-03	148	201	5	C0279702
Disease	Intellectual Disability	TMEM94 INPP4A KDM3B CSDE1 NRXN1 SACS RALGDS SYNE1 AGO1	3.72e-03	447	201	9	C3714756
Disease	asthma, body mass index	USP36 COL16A1	3.98e-03	14	201	2	EFO_0004340, MONDO_0004979
Disease	Testicular Germ Cell Tumor	ALOX5 RFWD3	3.98e-03	14	201	2	C1336708
Disease	5-methyluridine (ribothymidine) measurement	UPP1 CPT1B	3.98e-03	14	201	2	EFO_0020013
Disease	bacterial pneumonia (biomarker_via_orthology)	CXCL2 CXCL3	3.98e-03	14	201	2	DOID:874 (biomarker_via_orthology)
Disease	Non-Small Cell Lung Carcinoma	DAPK1 RRM1 ROS1 ENO1 ENO2	4.39e-03	156	201	5	C0007131
Disease	birth weight, pelvic organ prolapse	FBN2 COL5A1 ARAP3	4.56e-03	49	201	3	EFO_0004344, EFO_0004710
Disease	forehead morphology measurement	ADAM15 BACH1	4.57e-03	15	201	2	EFO_0007844
Disease	triacylglycerol 46:0 measurement	WDR72 RORB	4.57e-03	15	201	2	EFO_0010400
Disease	cortical surface area measurement	USP34 CTTNBP2 ADAM15 DAPK1 SLC26A1 LUZP1 FBN1 FBN2 JAG1 PKHD1 ZNF438 PRSS12 DOCK10 FAM76B DNAAF9 ADAM12 ADAMTS7 TNKS	5.03e-03	1345	201	18	EFO_0010736
Disease	focal segmental glomerulosclerosis	ALMS1 DNAH6	5.20e-03	16	201	2	EFO_0004236
Disease	Urticaria	ALOX5 SELE	5.20e-03	16	201	2	C0042109
Disease	Blood Coagulation Disorders	ACVRL1 COL5A1	5.20e-03	16	201	2	C0005779
Disease	Glycogen storage disease	PHKB ENO3	5.87e-03	17	201	2	cv:C0017919
Disease	fatty liver disease (is_marker_for)	INS MTTP	5.87e-03	17	201	2	DOID:9452 (is_marker_for)
Disease	Multiple congenital anomalies	CHUK NRXN1	5.87e-03	17	201	2	C0000772
Disease	1-Methylhistidine measurement	ALMS1 FBXL20	5.87e-03	17	201	2	EFO_0021543
Disease	platelet crit	KIF26A LRRK2 ACVRL1 NUP205 PHKB C6orf118 TRAFD1 ARHGAP29 KLRC2 DOCK10 NLRP3 LGALS8 ENO1 SORL1	5.89e-03	952	201	14	EFO_0007985
Disease	Congenital Fiber Type Disproportion	ITGA7 CCDC78	6.57e-03	18	201	2	C0546264
Disease	corneal topography	FBN1 COL5A1 SLC8A3 ADAMTS7	6.67e-03	109	201	4	EFO_0004345
Disease	Leukemia, Myelocytic, Acute	DAPK1 NOTCH2 XRCC2 ENO2 AGRN	6.76e-03	173	201	5	C0023467

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRNICAVLRCCQGIL	URB2	116	Q14146
KSIANCQVELLENCG	ABHD6	291	Q9BV23
LRVGCVLGTCQVQNL	ADM2	106	Q7Z4H4
ALCEAGCNVNIKNRE	DAPK1	496	P53355
GETKQNLTGLCQKVC	BACH1	611	O14867
CSTLQSCLKEQRLLG	ARAP3	371	Q8WWN8
LCSQCEAGRLLQKET	CACNA2D2	1061	Q9NY47
QRNIEDICICCGSLQ	DNMT3L	46	Q9UJW3
RKDCNLAAQLLQCSQ	BEGAIN	121	Q9BUH8
CQRVDLLGAQECRSK	ADAM15	646	Q13444
LLKSICGDCVQGQRA	COL16A1	951	Q07092
ISCNRQSGVKVEAQC	FBXO10	776	Q9UK96
VCNIVAGQRCIKKLT	AGO1	341	Q9UL18
NECQLKTIACRQGLQ	AGRN	946	O00468
CIQKDIGTQTNLKCR	ALMS1	2331	Q8TCU4
LNICSRCARLQGDNL	C8orf34	406	Q49A92
QASKVCQRLNCGVPL	CD5	76	P06127
GQVCVSELEQASCRK	CFAP46	1526	Q8IYW2
VLVKSNLQCCIADLG	ACVRL1	336	P37023
GKICLNRQCQNISVF	ADAM12	641	O43184
VILNQRTGKCSACNV	CSDE1	721	O75534
TCGNVCKGEVLRVQD	ABLIM2	26	Q6H8Q1
TQNILTFNKCCISGR	ATP8B3	501	O60423
LGINSHKRNCQLKCQ	DMXL2	86	Q8TDJ6
QGSNCEKRVDRCSLQ	DLL3	346	Q9NYJ7
SCLQACKEGLDINSL	CLSTN2	536	Q9H4D0
CLSNSLQVKGNTVCD	CCDC14	886	Q49A88
ACNCLLLKVNQIGSV	ENO2	336	P09104
LRCQCLQTLQGIHLK	CXCL3	41	P19876
QVRASRDLCINGICK	ADAMTS7	656	Q9UKP4
SKNCLQRLTDCVLSV	ANKRD33B	276	A6NCL7
LVRNEASATKCIACQ	RANBP2	1616	P49792
INGRCCLEEKVQSLL	PADI1	606	Q9ULC6
SAQCRLQLQVLTDKC	RFWD3	376	Q6PCD5
LQKRGIVEQCCTSIC	INS	86	P01308
RQLVTVCDCKLLANS	INPP4A	456	Q96PE3
EQLLECNKLCGRGQS	SLC2A12	596	Q8TD20
CCISCNSNIQIKLVG	NUP205	921	Q92621
TIDREQLCQKNLNCS	PCDH18	91	Q9HCL0
NNKICSLLSCGQKVL	ANKRD34B	466	A5PLL1
LKNLDIRCIRSLNGC	PAPOLB	191	Q9NRJ5
TGKNCQTLVNLCSRS	NOTCH2	1056	Q04721
NVKCTGNERSLADCI	PRSS12	566	P56730
QSRNLKCIALCEVIT	PARP8	781	Q8N3A8
AILCCNLIENVQRLG	MKKS	96	Q9NPJ1
LVKCQGSRLDDQRCA	GPSM2	601	P81274
SFQQQKLRVCEVCSA	LUC7L	181	Q9NQ29
RLINHSKCGNCQTKL	KMT5A	336	Q9NQR1
VLQASQCSLTKACRQ	GREB1	1241	Q4ZG55
KRAGCIVCNTLINEK	LGALS8	71	O00214
NCCEIVGSLRAINIS	MTMR8	611	Q96EF0
LQSLSNDVKNVGRCC	MMRN2	701	Q9H8L6
ICRNTTLVEGANLCL	GPM6A	161	P51674
ENCCGLKESQILSLL	CHUK	111	O15111
ENTICSLVESQKQCG	KIF11	691	P52732
INECLSRKLSGCSQD	LRP1	2941	Q07954
LNARQVVCGTKCNTL	DCAF12L2	106	Q5VW00
KTACAQGDQCLVLVL	MAP3K6	516	O95382
NVCCGQLLKEAVADR	AK8	296	Q96MA6
VKVRDQQGAESQLCC	PER2	296	O15055
ITGTLVRKLCQNEGC	MTTP	431	P55157
ACNLLQRGITNLCVI	PFKP	111	Q01813
QPSCKLQRLQLVSCG	NLRP1	891	Q9C000
QVRVAELSATQCCKN	DCAF8	261	Q5TAQ9
SGQCLRLQVSVCCKE	EFNA4	141	P52798
KNCELDVTCNIKNGR	F9	126	P00740
CGRECTNLKAALRQE	GSTO2	136	Q9H4Y5
AVNKCLDLNNCGLTT	LRRC31	86	Q6UY01
VNCRNCAIISDVKVR	KDM3B	1446	Q7LBC6
NQAKEGSSLICQVCE	LRRK2	736	Q5S007
GLKCEQIVNCTALES	SELE	171	P16581
LSQGQQLCKECRIAH	FAM76B	21	Q5HYJ3
ERATAALEQCVNLCK	KIF26A	1841	Q9ULI4
QARLCGQLKECTASA	GOLGA2P5	41	Q9HBQ8
CLNISVLSQKRCEDA	KLK5	206	Q9Y337
SQCALQKLILEDCGI	NLRP5	921	P59047
VKLTVNLDCIRINCN	NRXN1	776	Q9ULB1
SQLIRLGQCTKACEL	EXOC8	416	Q8IYI6
NIECLQISCAVGRLE	ITGA8	926	P53708
EVVQAQCRNLGCINA	IL17F	96	Q96PD4
ELEGCQSLKRNCLIV	LRRC8B	766	Q6P9F7
LTLTQCCLGQKQLAI	NLRC5	1356	Q86WI3
LNVCLENVIGNLLTC	SBF1	161	O95248
VCNLCRKQQEILTKS	RIMS1	161	Q86UR5
ITAKLCDVAQQRNCE	IFFO1	336	Q0D2I5
QAVCSTVRCKVSGNL	OXGR1	311	Q96P68
SKNSNLNVCNVCLGI	PUS10	101	Q3MIT2
CASEIENRALCLQGI	ARHGAP29	691	Q52LW3
SCNCLLLKVNQIGSV	ENO1	336	P06733
KCESANSICGRLQCI	ADAM30	546	Q9UKF2
NSICGRLQCINVETI	ADAM30	551	Q9UKF2
KQLRATQQTIASCLC	CDC45	421	O75419
NLRDLSKCVQGILQC	DNAH6	2296	Q9C0G6
LRCQCLQTLQGIHLK	CXCL2	41	P19875
IICKALNSNLQGCVT	DOCK10	396	Q96BY6
RCLQKGSLTIQQVND	LIG4	136	P49917
LLNECTSLCENRKNE	CENPF	1056	P49454
NLLELKESCIRNQDC	CLPSL1	31	A2RUU4
CENTICALNIRKQTS	CTTNBP2	991	Q8WZ74
KNCVDINECVLNSLL	FBN1	761	P35555
RCEININGATLKSQC	FBN1	861	P35555
QIVSCEVRLRDQCKG	CRISPLD1	291	Q9H336
TCQSCVDAVRKSLQG	CCS	21	O14618
ERKLQQELQKICTCS	C6orf118	246	Q5T5N4
KCLDQCSQGLVSNVV	DNAAF9	876	Q5TEA3
LLNCRGAIANSLTCV	DIP2C	991	Q9Y2E4
QAVVLCSCQGQLRQA	CCDC78	211	A2IDD5
TQQNPARTCKDLQLC	COL5A1	1631	P20908
NGQSCESRSKISLLC	CORIN	771	Q9Y5Q5
KNDCTQLCLSLNEER	LUZP1	131	Q86V48
LNQRGLLCKSERCVN	LTBP3	1261	Q9NS15
ANCVITTCLGNRSTK	RALGDS	441	Q12967
TLQCANISILENKLC	KLK9	161	Q9UKQ9
CNCQSTLQAILQELK	BEND7	166	Q8N7W2
LNSRQVVCGTKCNTL	DCAF12L1	106	Q5VU92
CSQVLCQEQGVCIRK	SPAM1	376	P38567
CGEDKICQSNLQLVR	ITGA7	681	Q13683
ACNCLLLKVNQIGSV	ENO3	336	P13929
KKCLQTQNGTICTVN	CCDC168	1881	Q8NDH2
IDECIQNGVLCKNGR	FBN2	576	P35556
RCEVNINGATLKSEC	FBN2	906	P35556
INECSLSDNLCRNGK	FBN2	1201	P35556
NRQGLCFAEVLQTIC	FBN2	2381	P35556
CIRTNINFSLQGKDC	CA10	296	Q9NS85
LRACGQTNVSCRVVK	PRSS46P	31	E5RG02
DKVINNCRNICNITT	SACS	3746	Q9NZJ4
SDSKLVENCVCLLRN	CTNND1	571	O60716
LSKQLVNVAERTCCC	COL6A6	1371	A6NMZ7
NVDISLGLVSCIQRC	CPT1B	76	Q92523
CGNLACRSDLQVAAK	FTCD	471	O95954
EILQKLNDCSCLASQ	PHKB	726	Q93100
TCLGCLELIAKNRQE	OGT	961	O15294
SFQQQKLRVCEVCSA	LUC7L2	181	Q9Y383
NTCQCLNGRIACSKV	JAG1	881	P78504
NQTPVVDCRKVCGLN	SLC8B1	46	Q6J4K2
DVCQKVDLLGASRCN	ICA1	211	Q05084
RCCSQLEKLATGCAQ	ITK	131	Q08881
VDQCCQALSQRLGTQ	MTX2	186	O75431
CKLQVLELDNCNLTS	NLRP3	941	Q96P20
LVNCKCQDQLLRVAV	NRIP2	161	Q9BQI9
KGSRLQEINDVCAIC	RNF139	536	Q8WU17
QASLRVLQQLKCCEK	TAS2R10	286	Q9NYW0
CGLQAAVVCVTLLNR	UPP1	261	Q16831
LKNNTCVKQENTCLR	SORL1	1066	Q92673
GALCQDCVRQVSRLQ	PSAPL1	181	Q6NUJ1
GVQSCCLADRVLQSQ	TDRD6	436	O60522
CQLLTELRNFTKGTC	SSPOP	5056	A2VEC9
CGNCGRNVLVKDLKT	TRAFD1	116	O14545
CLQASKGCQNKEQIL	SYNE1	3051	Q8NF91
AINTKAREQLICECG	ALOX5	406	P09917
CAVLQVNRLKSAQCG	KLRC2	206	P26717
CRNIEVLNLNGCTKT	FBXL20	116	Q96IG2
INCRVCQSLINLDGK	PIP4P2	56	Q8N4L2
VCKCLSQKITQLRGQ	SHLD1	121	Q8IYI0
TVKRRLECAANEVNC	TEKT5	171	Q96M29
TGRIGQLLVCNCIFK	TGM4	596	P49221
QTCLTVNIGAELIRC	PKHD1	1611	P08F94
TCLSGQNCTDIKVEQ	ARHGAP5	556	Q13017
VCQALRTLITKGCQA	RRP12	661	Q5JTH9
GIQHSKELNRTCCLN	TDGF1	71	P13385
KALQCQREACANILI	ANKRD30BL	111	A7E2S9
SCGLLTCKNQVLLGR	BTG2	131	P78543
VSLCNLERCSGNIKA	C12orf40	626	Q86WS4
ACEQLAIELSCRGVN	RECQL5	271	O94762
IRSICSTTNIQCKNG	RNASE4	81	P34096
CLRKLQHCREELNQS	TRAF3IP3	501	Q9Y228
ACDQVQVLLCANSRG	TIGD3	191	Q6B0B8
LRACIGDTLCQKLQN	UBA6	446	A0AVT1
DITKCACLQLTARNA	SETDB2	301	Q96T68
ICTRLLQEGIAQSKC	LINC02912	51	Q8N9X5
SLIILEGKNCTLQCN	TRAV10	31	A0A0B4J240
DLQLRKGCKSVNECN	ZNF738	141	Q8NE65
VVSLRCIACGVNLNS	TMPRSS2	236	O15393
LTNNCCGRQVANSII	TMPRSS11B	166	Q86T26
CNRKSNQQNLGTIKC	RRM1	411	P23921
NQQNLGTIKCSNLCT	RRM1	416	P23921
VRANQELLAVGCCNV	SLC26A1	371	Q9H2B4
CALSSQLNGKCIELV	TMEM94	756	Q12767
QCSECKKTTRQRNLN	TRIM51	51	Q9BSJ1
NCVSCGKNLESISQL	RBAK	136	Q9NYW8
SLSDNICAVCGQKII	RNF175	221	Q8N4F7
VKQLCSSQNVNCRDL	TNKS	666	O95271
NCKQCIERSASLISQ	MID1	301	O15344
ETARNLTQCQLECEK	PIBF1	476	Q8WXW3
ELCQNDQILLLKSGC	RORB	296	Q92753
RIILNCCDDSQLVKS	WDR72	601	Q3MJ13
GLARQLCTDCQLNKL	ZBED10P	51	Q96FA7
LQCLNAVRTVQSLAC	NUP188	1431	Q5SRE5
KIQKLSLQNCCLTGA	RNH1	86	P13489
KCLTHLEDLQRNCRQ	SENP6	226	Q9GZR1
NSCLKSCVTNLGQQL	ROS1	31	P08922
AIGCVRNLKQIVDCL	USP9Y	1511	O00507
LQQSGVCCKQKLTSI	PIGN	751	O95427
DVLQAETSQQLCCQK	SNX6	336	Q9UNH7
GCLQLTNIKLNDDNC	TLR6	221	Q9Y2C9
VNLQESTLRKCSQCL	XRCC2	166	O43543
DLCRGIVQLCFNEQS	ZNFX1	476	Q9P2E3
QGRNDIATVSICKKC	ZDHHC16	146	Q969W1
TLNLCNIDVTQKCLI	ATP6V0A1	306	Q93050
IFQGTLTNETRCLNC	USP46	171	P62068
RGTQNQLRCELCDVS	ZFR	376	Q96KR1
CITLNEGKSILCDIN	VPS13B	3506	Q7Z7G8
CGKTFNQQLTLNICR	ZNF765	416	Q7L2R6
CNGLNQCLTATQSKI	ZNF85	131	Q03923
INNCLICGRIVCEQE	TRIP4	181	Q15650
CLQSVCNSGLKQKVL	VPS33A	411	Q96AX1
IVLLVCNRACTGQQG	USP31	456	Q70CQ4
SKCRTCLQQRNSLQE	USP34	3321	Q70CQ2
IQAKGNIFQRLISCC	SLC6A14	586	Q9UN76
CVTGLCGLDRKEVQQ	TOPBP1	206	Q92547
DEVKLQIKCGRCQIT	ZNF438	641	Q7Z4V0
GIQHSKELNRTCCLN	TDGF1P3	71	P51864
SSRQNKSQVCCLREQ	THAP4	351	Q8WY91
GQLLSQVTCLACDNK	USP44	471	Q9H0E7
LCSILKVCQGDGQLQ	ZNF300	121	Q96RE9
QKACLNGCAKLDRQT	USP36	221	Q9P275
RVQTSIAVCKLQACA	TTF2	746	Q9UNY4
QCLENCGAVLLTVVR	SLC8A3	406	P57103
AGRCLSVDCSLKAQQ	EXD3	691	Q8N9H8
KRNKRDQCCIISGES	MYO7B	146	Q6PIF6