Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

SEMG1 POLR1A MYCBP2 KDM4C MYO9B ZMYND8 FBXO11 GRIN2A CLIP1 PHF2 RASGRP1 SIRT2 UBR5 ERAP2 ABCC8 ST18 ALPP ALPG

1.10e-0589112518GO:0008270
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

2.78e-05101253GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

5.06e-05121253GO:0016175
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 OBSCN NCF1C NCF1B

6.59e-05351254GO:0043325
GeneOntologyMolecularFunctionpyrroline-5-carboxylate reductase activity

PYCR1 PYCR2

2.31e-0441252GO:0004735
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

2.53e-04201253GO:0050664
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARHGEF28 MYCBP2 MYO9B OBSCN ARHGEF12 EPS8L1 RGS12 RASGRP1 SRGAP1 RASGRP3 ARHGAP12

3.48e-0450712511GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARHGEF28 MYCBP2 MYO9B OBSCN ARHGEF12 EPS8L1 RGS12 RASGRP1 SRGAP1 RASGRP3 ARHGAP12

3.48e-0450712511GO:0030695
GeneOntologyMolecularFunctiontransition metal ion binding

SEMG1 POLR1A MYCBP2 KDM4C MYO9B ZMYND8 FBXO11 GRIN2A CLIP1 PHF2 RASGRP1 SIRT2 UBR5 ERAP2 ABCC8 ST18 ALPP ALPG

4.34e-04118912518GO:0046914
GeneOntologyMolecularFunctionenzyme regulator activity

PRPSAP2 ARHGEF28 MYCBP2 MYO9B NCF1 OBSCN ARHGEF12 NBN EPS8L1 RGS12 AZIN1 RASGRP1 FRY KIDINS220 SRGAP1 RASGRP3 ARHGAP12 TAOK1 NCF1C NCF1B

5.06e-04141812520GO:0030234
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPP ALPG

5.74e-0461252GO:0004035
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

ARHGEF28 MYCBP2 OBSCN ARHGEF12 EPS8L1 RASGRP1 RASGRP3

6.36e-042311257GO:0005085
GeneOntologyMolecularFunctionenzyme activator activity

MYO9B NCF1 ARHGEF12 NBN RGS12 AZIN1 SRGAP1 RASGRP3 ARHGAP12 TAOK1 NCF1C NCF1B

8.56e-0465612512GO:0008047
GeneOntologyMolecularFunctionmagnesium ion binding

PRPSAP2 POLR1A THTPA GEN1 FIGNL1 ALPP ALPG

9.42e-042471257GO:0000287
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

2.05e-0651233GO:0070946
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

7.12e-0671233GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

7.12e-0671233GO:0070947
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

3.30e-05111233GO:0060264
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

5.67e-05131233GO:0002536
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 DCD NCF1C NCF1B

7.60e-05381234GO:0051873
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 GGT7 NCF1C NCF1B

1.03e-04411234GO:0006691
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

1.09e-04161233GO:0070944
GeneOntologyBiologicalProcesskilling of cells of another organism

SEMG1 NCF1 NTS DCD NCF1C NCF1B

1.24e-041291236GO:0031640
GeneOntologyBiologicalProcessdisruption of cell in another organism

SEMG1 NCF1 NTS DCD NCF1C NCF1B

1.24e-041291236GO:0141061
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

SEMG1 NCF1 NTS DCD NCF1C NCF1B

1.41e-041321236GO:0141060
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

1.58e-04181233GO:0001878
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

1.87e-04191233GO:0070943
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

2.19e-04201233GO:0002679
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

2.54e-04211233GO:0070942
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 NCF1C NCF1B

2.93e-04221233GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

2.93e-04221233GO:0050665
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

3.36e-04231233GO:0060263
GeneOntologyBiologicalProcessthiamine-containing compound biosynthetic process

SLC19A3 THTPA

3.49e-0451232GO:0042724
GeneOntologyBiologicalProcessthiamine diphosphate biosynthetic process

SLC19A3 THTPA

3.49e-0451232GO:0009229
GeneOntologyBiologicalProcessthiamine diphosphate metabolic process

SLC19A3 THTPA

3.49e-0451232GO:0042357
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

ARHGEF28 MYO9B OBSCN ARHGEF12 EPS8L1 GRIN2A RASGRP1 SRGAP1 RASGRP3 ARHGAP12 GRAP2

3.81e-0453812311GO:0007264
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

1.52e-04181233GO:0043020
GeneOntologyCellularComponentmyofibril

FLNC MYOM3 OBSCN KY XIRP2 TNNC2 ALPP ALPG

2.15e-042731238GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

FLNC MYOM3 OBSCN KY XIRP2 TNNC2 ALPP ALPG

3.24e-042901238GO:0043292
MousePhenosingle kidney

NCF1 BMP4 GLI3 NCF1C NCF1B GEN1

6.18e-06611056MP:0003604
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

8.10e-0661053MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

8.10e-0661053MP:0003184
MousePhenoliver abscess

NCF1 NCF1C NCF1B

1.41e-0571053MP:0003332
MousePhenodecreased vasoconstriction

NCF1 ARHGEF12 NCF1C NCF1B

1.98e-05221054MP:0003026
MousePhenoincreased circulating renin level

NCF1 NCF1C NCF1B WNK4

2.38e-05231054MP:0003352
MousePhenoimpaired granulocyte bactericidal activity

NCF1 NCF1C NCF1B

4.76e-05101053MP:0005074
MousePhenoabnormal circulating renin level

NCF1 NCF1C NCF1B WNK4

6.18e-05291054MP:0003349
MousePhenoimpaired smooth muscle contractility

NCF1 ARHGEF12 NCF1C NCF1B

1.32e-04351054MP:0000740
DomainArp1

ACTR1B ACTR1A

4.16e-0521212IPR029909
DomainSH3

AMPH AHI1 NCF1 OBSCN EPS8L1 SRGAP1 ARHGAP12 GRAP2

8.26e-052161218SM00326
DomainSH3

AMPH AHI1 NCF1 OBSCN EPS8L1 SRGAP1 ARHGAP12 GRAP2

8.26e-052161218PS50002
DomainSH3_domain

AMPH AHI1 NCF1 OBSCN EPS8L1 SRGAP1 ARHGAP12 GRAP2

9.38e-052201218IPR001452
DomainSH3_1

AMPH AHI1 NCF1 EPS8L1 SRGAP1 ARHGAP12 GRAP2

9.66e-051641217PF00018
DomainTranscrp_activ_Zfx/Zfy-dom

ZFY ZNF711

1.24e-0431212IPR006794
Domain-

PYCR1 PYCR2

1.24e-04312121.10.3730.10
DomainZfx_Zfy_act

ZFY ZNF711

1.24e-0431212PF04704
DomainP5CR_dimer

PYCR1 PYCR2

1.24e-0431212PF14748
DomainP5CR_dimer

PYCR1 PYCR2

1.24e-0431212IPR029036
DomainP5CR

PYCR1 PYCR2

2.48e-0441212PS00521
DomainPyrroline-COOH_reductase

PYCR1 PYCR2

2.48e-0441212IPR000304
DomainAlk_phosphatase

ALPP ALPG

2.48e-0441212PF00245
DomainAlkaline_phosphatase_AS

ALPP ALPG

2.48e-0441212IPR018299
DomainAlkaline_phosphatase

ALPP ALPG

2.48e-0441212IPR001952
DomainalkPPc

ALPP ALPG

2.48e-0441212SM00098
DomainALKALINE_PHOSPHATASE

ALPP ALPG

2.48e-0441212PS00123
DomainFG_GAP

ITGA10 CRTAC1 ITGAE

3.73e-04221213PS51470
DomainFG-GAP

ITGA10 CRTAC1 ITGAE

4.86e-04241213PF01839
DomainFG-GAP

ITGA10 CRTAC1 ITGAE

4.86e-04241213IPR013517
DomainC1_1

ARHGEF28 MYO9B RASGRP1 RASGRP3

5.08e-04571214PF00130
DomainPbH1

FBXO11 PKHD1L1

6.14e-0461212SM00710
DomainPbH1

FBXO11 PKHD1L1

6.14e-0461212IPR006626
DomainZF_DAG_PE_1

ARHGEF28 MYO9B RASGRP1 RASGRP3

7.89e-04641214PS00479
DomainZF_DAG_PE_2

ARHGEF28 MYO9B RASGRP1 RASGRP3

7.89e-04641214PS50081
DomainC1

ARHGEF28 MYO9B RASGRP1 RASGRP3

8.37e-04651214SM00109
DomainProC_N

PYCR1 PYCR2

8.56e-0471212IPR028939
DomainZnF_UBR1

FBXO11 UBR5

8.56e-0471212SM00396
DomainZF_UBR

FBXO11 UBR5

8.56e-0471212PS51157
DomainF420_oxidored

PYCR1 PYCR2

8.56e-0471212PF03807
Domainzf-UBR

FBXO11 UBR5

8.56e-0471212PF02207
DomainZnf_UBR

FBXO11 UBR5

8.56e-0471212IPR003126
DomainPE/DAG-bd

ARHGEF28 MYO9B RASGRP1 RASGRP3

8.86e-04661214IPR002219
DomainPectin_lyase_fold/virulence

FBXO11 PKHD1L1

1.14e-0381212IPR011050
DomainEGF_CA

STAB2 CRTAC1 CUBN F10 MEGF6

1.19e-031221215SM00179
DomainEGF-like_Ca-bd_dom

STAB2 CRTAC1 CUBN F10 MEGF6

1.28e-031241215IPR001881
DomainFilamin

FLNC MYCBP2

2.20e-03111212PF00630
DomainFILAMIN_REPEAT

FLNC MYCBP2

2.20e-03111212PS50194
DomainFilamin/ABP280_rpt

FLNC MYCBP2

2.20e-03111212IPR001298
DomainFilamin/ABP280_repeat-like

FLNC MYCBP2

2.20e-03111212IPR017868
DomainEGF_dom

STAB2 CUBN

2.63e-03121212IPR024731
DomainEGF_3

STAB2 CUBN

2.63e-03121212PF12947
DomainPHD

KDM4C NSD2 ZMYND8 PHF2

2.68e-03891214SM00249
DomainZnf_FYVE_PHD

KDM4C NSD2 ZMYND8 PHF2 MTMR3

2.70e-031471215IPR011011
DomainZnf_PHD

KDM4C NSD2 ZMYND8 PHF2

2.90e-03911214IPR001965
DomainZF_PHD_2

KDM4C NSD2 ZMYND8 PHF2

3.39e-03951214PS50016
DomainZF_PHD_1

KDM4C NSD2 ZMYND8 PHF2

3.52e-03961214PS01359
DomainEGF_Ca-bd_CS

CRTAC1 CUBN F10 MEGF6

3.65e-03971214IPR018097
DomainEGF_CA

CRTAC1 CUBN F10 MEGF6

3.93e-03991214PS01187
DomaintRNAsynth_Ia_anticodon-bd

IARS1 CARS2

4.14e-03151212IPR009080
DomainActin_CS

ACTR1B ACTR1A

4.71e-03161212IPR004001
DomainACTINS_2

ACTR1B ACTR1A

5.31e-03171212PS00432
DomainIntegrin_alpha-2

ITGA10 ITGAE

5.95e-03181212IPR013649
DomainINTEGRIN_ALPHA

ITGA10 ITGAE

5.95e-03181212PS00242
DomainIntegrin_alpha2

ITGA10 ITGAE

5.95e-03181212PF08441
DomainIntegrin_alpha

ITGA10 ITGAE

5.95e-03181212IPR000413
DomainActin/actin-like_CS

ACTR1B ACTR1A

5.95e-03181212IPR020902
PathwayPID_RHOA_REG_PATHWAY

ARHGEF28 MYO9B OBSCN ARHGEF12 SRGAP1

1.24e-0546935M68
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

2.27e-059933MM14524
Pubmed

Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase.

NCF1 BMP4 NCF1C NCF1B

1.75e-104128415388638
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNC HIVEP2 MYCBP2 MYO9B PPRC1 NSD2 MYOM3 OBSCN ANKHD1 GGT7 NOD2 ACTR1A BMP4 SIRT2 AATK MEGF6 MCM3AP IFRD2 MTMR3 CPSF1 BAHCC1

7.09e-1011051282135748872
Pubmed

Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation.

NCF1 BMP4 NCF1C NCF1B

8.73e-105128416769910
Pubmed

A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways.

NCF1 NOD2 NCF1C NCF1B

8.73e-105128423322906
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNC POLR1A MYCBP2 MYO9B IARS1 PSMD7 ANKHD1 NCAPH EFTUD2 SART1 ACTR1B ACTR1A UBR5 DCD MCM3AP CPSF1 PYCR1 EIF3D ALDH1B1 PIP4K2C PYCR2

2.44e-0813531282129467282
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

4.87e-083128327044504
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

4.87e-083128318787174
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

4.87e-083128324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

4.87e-083128322184329
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

4.87e-083128333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

4.87e-083128320142487
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

4.87e-083128325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

4.87e-083128339357591
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

4.87e-083128311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

4.87e-083128331118934
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

4.87e-083128316041040
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

4.87e-083128318703411
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

4.87e-083128317307863
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

4.87e-083128327829407
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

4.87e-083128322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

4.87e-083128323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

4.87e-083128328274989
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

4.87e-083128312364355
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

4.87e-083128334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

4.87e-083128328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

4.87e-083128310670582
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

4.87e-083128326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

4.87e-083128319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

4.87e-083128320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

4.87e-083128323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

4.87e-083128334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

4.87e-083128317114280
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

4.87e-083128325989352
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

4.87e-083128317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

4.87e-083128317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

4.87e-083128336592568
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

4.87e-083128330504842
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

4.87e-083128333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

4.87e-083128323965970
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

4.87e-083128315513930
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

4.87e-083128315033459
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

4.87e-083128320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

4.87e-083128320817944
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

4.87e-083128336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

4.87e-083128323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

4.87e-083128321253614
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

4.87e-083128315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

4.87e-083128331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

4.87e-083128310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

4.87e-083128334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

4.87e-083128325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

4.87e-083128314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

4.87e-083128322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

4.87e-083128312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

4.87e-083128311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

4.87e-083128315936744
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

4.87e-083128325628043
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1 NCF1C NCF1B

4.87e-083128312560337
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1 NCF1C NCF1B

4.87e-083128335276443
Pubmed

Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.

NCF1 NCF1C NCF1B

4.87e-083128319381132
Pubmed

Identification of a novel NCF-1 (p47-phox) pseudogene not containing the signature GT deletion: significance for A47 degrees chronic granulomatous disease carrier detection.

NCF1 NCF1C NCF1B

4.87e-083128312176908
Pubmed

A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.

NCF1 NCF1C NCF1B

4.87e-08312839329953
Pubmed

Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.

NCF1 NCF1C NCF1B

4.87e-083128310799876
Pubmed

Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.

NCF1 NCF1C NCF1B

4.87e-083128311834706
Pubmed

A model of chronic enthesitis and new bone formation characterized by multimodal imaging.

NCF1 NCF1C NCF1B

4.87e-083128330045841
Pubmed

Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.

NCF1 NCF1C NCF1B

4.87e-083128319635825
Pubmed

The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells.

NCF1 NCF1C NCF1B

4.87e-083128335788118
Pubmed

Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.

NCF1 NCF1C NCF1B

4.87e-083128317310103
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

4.87e-083128318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

4.87e-083128310678931
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

4.87e-083128317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

4.87e-083128324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

4.87e-083128310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

4.87e-083128325474113
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

4.87e-083128326209274
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

4.87e-083128311018074
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

4.87e-08312839116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

4.87e-083128320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

4.87e-083128321570954
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

4.87e-083128312958309
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

4.87e-083128323482812
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

4.87e-083128310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

4.87e-083128310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

4.87e-083128321435178
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

4.87e-083128329228045
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

4.87e-083128322155727
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

4.87e-083128324576409
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

4.87e-083128326645958
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

4.87e-083128324549323
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

4.87e-083128320881184
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

4.87e-083128319168575
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

4.87e-083128319503084
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

4.87e-083128311156938
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

4.87e-083128310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

4.87e-083128327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

4.87e-083128320702812
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

4.87e-083128326455429
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

4.87e-083128315626477
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

4.87e-083128319077231
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

4.87e-083128322319452
InteractionDCTN1 interactions

FLNC AHI1 MYCBP2 NASP PSMD7 NCAPH CLIP1 EFTUD2 NOD2 ACTR1B ACTR1A AATK EIF3D GEN1 VPS29

4.64e-0749712515int:DCTN1
Cytoband2q37

SLC19A3 ALPP ALPG

8.99e-053112832q37
GeneFamilyAlkaline phosphatases

ALPP ALPG

1.12e-0447921072
GeneFamilyUbiquitin protein ligase E3 component n-recognins

FBXO11 UBR5

3.90e-047792785
GeneFamilyGla domain containing

TTR F10

1.43e-03137921250
GeneFamilyCD molecules|Integrin alpha subunits

ITGA10 ITGAE

2.76e-03187921160
GeneFamilyAminoacyl tRNA synthetases, Class I

IARS1 CARS2

3.07e-0319792131
CoexpressionRAPA_EARLY_UP.V1_DN

SOX10 NCF1 NCAPH F10 LGALS3BP ACTR1B MTMR3 ALDH1B1

3.61e-061861278M2643
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

AMPH HIVEP2 MYCBP2 KDM4C MYO9B ZMYND8 NBN CLIP1 ITPR1 AZIN1 KIDINS220 UBR5 ARHGAP12 MTMR3 CRYBG3 PPIP5K2

4.04e-0685612716M4500
CoexpressionVANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP

PRUNE2 VEZT GON4L FBXO11 CARS2

1.74e-05661275M1752
CoexpressionHOWARD_DENDRITIC_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP

NCF1 LGALS3BP NCF1C

1.78e-05111273M40947
CoexpressionNAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

NCF1 GON4L NBN ANKHD1 ITPR1 RASGRP1 PAXBP1 MTRR NCF1C NCF1B

2.57e-0539912710M41172
CoexpressionONKEN_UVEAL_MELANOMA_UP

FLNC AHI1 IARS1 ZMYND8 NASP NBN CLIP1 AZIN1 FRY UBR5 MCM3AP CPSF1 UGGT2 PPIP5K2

3.03e-0579012714M12490
CoexpressionGSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN

TICRR THTPA ITPR1 LRP11 NOL7 GEN1 FIGNL1

5.42e-051991277M8109
ToppCellfacs-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 AHI1 TTR LGALS3BP ABCC8 LRP11 PYCR2 ST18

9.13e-08193128815c86e20b97b6983410b36d308cddff56d141c98
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTS CRTAC1 TTR F10 RASGRP1 ABCC8 ST18

1.06e-0618412871e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 TTR LGALS3BP ITPR1 ABCC8 LRP11 ST18

1.36e-061911287b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 TTR LGALS3BP ITPR1 ABCC8 LRP11 ST18

1.36e-061911287657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRUNE2 TICRR FLNC ITGA10 NCAPH ABCC8

5.82e-061551286cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KDM4C IARS1 CRTAC1 RASGRP1 MCM3AP GRAP2

8.92e-061671286dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC MYOM3 OBSCN C4orf54 FRY XIRP2

9.87e-0617012863f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PPRC1 OBSCN PKHD1L1 ZNF711 RASGRP3 TNNC2

1.16e-05175128669ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC MYOM3 OBSCN C4orf54 FRY XIRP2

1.20e-0517612869df7a124ebafb0087da0cda133a394275d7bed81
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNC SLC19A3 GRIN2A TNNC2 GEN1

1.21e-051031285eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOM3 CRTAC1 PKHD1L1 TTR ABCC8 ST18

1.24e-05177128643dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

1.41e-051811286b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

1.41e-051811286dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

FLNC MYOM3 OBSCN C4orf54 FRY XIRP2

1.45e-051821286287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 TTR LGALS3BP ITPR1 ABCC8 ST18

1.75e-051881286e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC COL15A1 MYOM3 OBSCN FRY XIRP2

1.85e-051901286918ad5037881212008f9f69d5df5da91fd01422c
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

1.85e-051901286103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCellwk_20-22-Endothelial-Lymph_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

1.91e-051911286631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 TTR LGALS3BP KY ABCC8 PYCR2

1.91e-051911286a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 HIVEP2 NTS CRTAC1 PKHD1L1 RASGRP3

1.97e-051921286b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 HIVEP2 NTS CRTAC1 PKHD1L1 RASGRP3

1.97e-051921286ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.09e-051941286bc03d0f8dca9f4ba10db2f2274293f8b119e8951
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.09e-0519412869441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.09e-051941286640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNC STAB2 NTS PKHD1L1 MEGF6 RASGRP3

2.15e-0519512868e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FLNC MYOM3 C4orf54 KY SIRT2 TNNC2

2.15e-05195128680b973d2a23ef9b101c90e1635e68c9a3f78f65d
ToppCellwk_15-18-Endothelial-Lymph_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.21e-051961286ff627244d7f5fd6a2ec009dae32d3509f0e2d95e
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.21e-051961286b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.21e-051961286a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 COL15A1 ITGA10 ITPR1 FRY ALDH1B1

2.27e-05197128671367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 COL15A1 ITGA10 ITPR1 FRY ALDH1B1

2.27e-0519712860f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AMPH AHI1 HIVEP2 GRIN2A ITPR1 FRY

2.34e-051981286c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AMPH AHI1 HIVEP2 GRIN2A ITPR1 FRY

2.34e-0519812868ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellmedial-Endothelial-Lymphatic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.34e-05198128641983d405215b974044e2e9e6c212b134336a6fe
ToppCellmedial-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.34e-051981286e4274584512a72270087a1ab104fab449a2f83bc
ToppCellmedial-Endothelial-Lymphatic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.34e-0519812861760fede363544bc0fa2e22fe36aff522abd2525
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.47e-05200128676e90231aa94afc12e618da8ae314c51644acab4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.47e-052001286e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.47e-052001286b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC STAB2 NTS CRTAC1 PKHD1L1 RASGRP3

2.47e-05200128635f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRUNE2 C2orf81 KY WDR87 RASGRP3

9.09e-05157128529622bac6b16bb39cec4319bf4c4f92d33345e8a
ToppCellIIF-Lymphocyte-B-Plasmablast|IIF / Disease, Lineage and Cell Type

TICRR PKHD1L1 KY RASGRP3 PYCR1

1.02e-0416112854d78985e7b11e92591e75a4864fd769882db2d1c
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 TICRR MYCBP2 CUBN WDR87

1.05e-041621285d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.05e-0416212852ac02523348660e514d464f8f2434ee0c312d784
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 NTS PKHD1L1 CDH10

1.12e-0416412854cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 NTS PKHD1L1 CDH10

1.12e-0416412857a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 NTS PKHD1L1 CDH10

1.12e-0416412855e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 NTS PKHD1L1 CDH10

1.12e-041641285f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR NSD2 NASP C2orf81 FIGNL1

1.15e-04165128588681101d7cf60b99b8ace5d8c0944323b937306
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRTAC1 TTR F10 ABCC8 ST18

1.18e-041661285afba41e15478053f11815acf568d29187de75492
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OBSCN PKHD1L1 BMP4 WNK4

1.21e-041671285a4a795751644b22af616335379e64ae95175180c
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SOX10 SIRT2 PYCR1 ST18 FIGNL1

1.28e-04169128550cc0f5a022b95986949db63208a627cef9f4a69
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAMDC4 F10 BMP4 PYCR1

1.32e-049012846adc78899a08d48da8ed4618ecf866c9ed9be059
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAMDC4 F10 BMP4 PYCR1

1.32e-04901284a74f8172780adc1410e36e2718412010ee0ebf1f
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAMDC4 F10 BMP4 PYCR1

1.32e-04901284909ad62d175b657d8e541b0981ce8fed0ba7ed6c
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAMDC4 F10 BMP4 PYCR1

1.32e-04901284936c5078677ec934f3049d8aa5a14d930aa2e6dc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THTPA CRTAC1 RGS12 RASGRP1 RASGRP3

1.36e-04171128575279ca22f5dd6cfee11c83f3a7b5f828cdec1c6
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF12 NCAPH RGS12 RASGRP3 FIGNL1

1.39e-041721285490745024730df6357f6c2b81d7a64e21557c0d5
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTS TTR ABCC8 LRP11 ST18

1.43e-041731285f31e738c2b3b319fb40b0b16b2393a51c9a8999c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TICRR ITGAE NCAPH GEN1 FIGNL1

1.51e-041751285a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TICRR NCAPH PKHD1L1 RASGRP3 MCM3AP

1.51e-04175128589bf89466191da14896ed8928027f5b911436c22
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

GRIN2A ACTR1B RASGRP1 TAOK1 SVOP

1.55e-041761285d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTR F10 ABCC8 FAM167A ST18

1.68e-041791285f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 NTS PKHD1L1 RASGRP3 ALPG

1.68e-0417912851c0c0647a111f691dae55f4ed8c51006059ce020
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRUNE2 HIVEP2 FRY XIRP2 CRYBG3

1.68e-04179128514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NTS ABCC8 LRP11 ST18

1.72e-0418012859db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

PKHD1L1 RASGRP3 PYCR1 UGGT2 CRYBG3

1.77e-0418112859b33f531c8ac776706ec7e2d47e95ba30b6ce13c
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTR F10 ABCC8 ST18 SVOP

1.77e-041811285cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC MYOM3 OBSCN FRY XIRP2

1.77e-041811285719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

PKHD1L1 RASGRP3 PYCR1 UGGT2 CRYBG3

1.77e-041811285a0549a8c2b5b30e91fae3052f398e48baa45d7ff
ToppCellRV|World / Chamber and Cluster_Paper

ZMYND8 MYOM3 OBSCN EFCAB2 XIRP2

1.77e-041811285bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTR F10 ABCC8 FAM167A ST18

1.77e-041811285af031661af28f99d906d8e013b4949133b44a2e6
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR RGS12 KY FAM167A FIGNL1

1.81e-04182128539f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 VEZT THTPA C2orf81 AATK

1.81e-0418212856fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HIVEP2 ZMYND8 BMP4 ARHGAP12 CRYBG3

1.81e-0418212857b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTS TTR F10 ABCC8 SVOP

1.81e-04182128527a27a3eaeacb087c9601d5bb1c9e57cdfcd9d77
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TTR ABCC8 FAM167A SVOP CDH10

1.86e-0418312858820cfed27b292bc0bc9cde4005219ed41900552
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.86e-041831285764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.86e-04183128538a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.86e-041831285bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OBSCN PKHD1L1 XIRP2 ST18

1.91e-0418412852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OBSCN PKHD1L1 XIRP2 ST18

1.91e-041841285ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 KY ABCC8 LRP11 ST18

1.91e-0418412853e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OBSCN PKHD1L1 XIRP2 ST18

1.91e-0418412852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

FLNC MYOM3 OBSCN FRY XIRP2

1.91e-041841285ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 EPS8L1 F10 GGT7 AATK

1.91e-041841285e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.91e-0418412853b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 KY ABCC8 LRP11 ST18

1.91e-0418412851e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC MYOM3 OBSCN FRY XIRP2

1.96e-041851285549eeb521c3985bff396ea0f202db21822efa51f
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTS EPS8L1 PKHD1L1 XIRP2 RASGRP3

1.96e-041851285241ea1e178fffef9e7df971de739e794332d5173
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PRUNE2 SOX10 TTR NYAP1 ST18

1.96e-041851285f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

FLNC STAB2 NTS PKHD1L1 RASGRP3

1.96e-04185128597a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 FLNC BMP4 PYCR1 WNK4

2.01e-041861285c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

FLNC STAB2 NTS PKHD1L1 RASGRP3

2.01e-0418612856b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 TTR ABCC8 ST18 SVOP

2.06e-04187128598477ba04a42a8da80a72f41a182429f46283595
ToppCellmild_COVID-19-Plasmablast|World / disease group, cell group and cell class (v2)

TICRR PKHD1L1 WDR87 RASGRP3 PYCR1

2.11e-0418812859a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC STAB2 PKHD1L1 MEGF6 RASGRP3

2.11e-04188128526915db8863f4115b46a81982e187322e21600fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC STAB2 PKHD1L1 MEGF6 RASGRP3

2.11e-0418812853f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMPH OBSCN ITGA10 GRIN2A BMP4

2.11e-041881285997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 TTR LGALS3BP ABCC8 PYCR2

2.11e-04188128563773854bf8430fb8229edb385b953a89833d08c
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

AHI1 HIVEP2 VEZT ZMYND8 ITGA10 GON4L AATK ARHGAP12 BAHCC1

1.63e-0619812696907_UP
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

6.69e-0751213DOID:3265 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 NCF1C NCF1B

1.44e-05121213DOID:7148 (implicated_via_orthology)
Diseaseautosomal recessive cutis laxa type IIB (implicated_via_orthology)

PYCR1 PYCR2

1.67e-0521212DOID:0070137 (implicated_via_orthology)
DiseaseIntellectual Disability

KIFBP AHI1 HIVEP2 NSD2 GON4L FRY PYCR1 TAOK1 PYCR2

9.81e-054471219C3714756
DiseaseInsulinogenic index measurement

MYCBP2 PPIP5K2

1.65e-0451212EFO_0009961
DiseaseMicrocephaly

KIFBP NSD2 IARS1 NCAPH

1.69e-04671214C0025958
Diseaseleft ventricular mass index

FLNC TTR KY

3.67e-04341213EFO_0009290
Diseasebreast cancer (is_implicated_in)

KDM4C NBN F10 NOD2 UBR5

3.93e-041501215DOID:1612 (is_implicated_in)
Diseaseleft ventricular systolic function measurement

FLNC OBSCN TTR

7.88e-04441213EFO_0008206
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A F10

8.95e-04111212DOID:9279 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

KY TNNC2

1.07e-03121212C0270960
DiseaseL2 Acute Lymphoblastic Leukemia

NSD2 NBN MTRR

1.15e-03501213C0023453
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP2 BMP4

1.26e-03131212DOID:0050787 (implicated_via_orthology)
DiseaseCakut

BMP4 SRGAP1

1.26e-03131212C1968949
DiseaseChildhood Acute Lymphoblastic Leukemia

NSD2 NBN MTRR

1.28e-03521213C0023452
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

FLNC KIF28P

1.47e-03141212DOID:898 (implicated_via_orthology)
Diseasetrimethylamine-N-oxide measurement

CUBN ST18

1.47e-03141212EFO_0010541
DiseaseArthritis, Psoriatic

NOD2 BMP4

1.47e-03141212C0003872
DiseaseFEV/FEC ratio

TSHZ3 HIVEP2 COL15A1 ARHGEF28 NASP ITPR1 PHF2 BMP4 MEGF6 RASGRP3 ARHGAP12 MTMR3 UGGT2

1.61e-03122812113EFO_0004713
DiseaseLibman-Sacks Disease

NCF1 RASGRP1 RASGRP3

1.76e-03581213C0242380
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

NSD2 NBN MTRR

2.04e-03611213C1961102
Diseaserefractive error

GRIN2A BMP4 NYAP1 ST18 ALPP ALPG

2.31e-033261216MONDO_0004892
Diseaseinsomnia measurement

MYCBP2 ZMYND8 PHF2 ACTR1A RASGRP1 UBR5 PPIP5K2

2.39e-034431217EFO_0007876
DiseaseColorectal Carcinoma

FLNC OBSCN GRIN2A CUBN BMP4 GLI3 ABCC8 MCM3AP MTRR

2.47e-037021219C0009402
DiseaseProfound Mental Retardation

KIFBP AHI1 GON4L FRY

2.62e-031391214C0020796
DiseaseMental Retardation, Psychosocial

KIFBP AHI1 GON4L FRY

2.62e-031391214C0025363
DiseaseMental deficiency

KIFBP AHI1 GON4L FRY

2.62e-031391214C0917816
Diseasebipolar disorder

SEMG1 HIVEP2 POLR1A ZMYND8 MYOM3 GRIN2A ANKHD1 SNX19

2.66e-035771218MONDO_0004985
Diseasecerebral microbleeds

AMPH SRGAP1

2.72e-03191212EFO_0010059
Diseasedentures

PRUNE2 MTMR3 BAHCC1

3.01e-03701213EFO_0010078
Diseasedental caries, dentures

PRUNE2 MTMR3 BAHCC1

3.01e-03701213EFO_0003819, EFO_0010078
Diseasedilated cardiomyopathy

FLNC TTR

3.02e-03201212EFO_0000407
DiseaseLupus Erythematosus, Systemic

NCF1 RASGRP1 RASGRP3

3.14e-03711213C0024141
Diseasebreast carcinoma

ARHGEF28 KDM4C MYO9B PPRC1 ARHGEF12 TASOR2 ITPR1 MTMR3 NBPF10 PCSK7 BAHCC1

3.19e-03101912111EFO_0000305
Diseasestem Cell Growth Factor beta measurement

STAB2 KDM4C ZNF197

3.66e-03751213EFO_0008292
Diseaseplatelet component distribution width

PRUNE2 AHI1 HIVEP2 MYO9B ZMYND8 CRTAC1 CUBN C4orf54 NYAP1

3.98e-037551219EFO_0007984
DiseaseDrugs used in diabetes use measurement

TSHZ3 HIVEP2 MYCBP2 RASGRP1 ABCC8

4.09e-032551215EFO_0009924

Protein segments in the cluster

PeptideGeneStartEntry
ESGSEEEGEIHEKAR

PRPF4B

141

Q13523
GDVAELRVELTHGAE

MAMDC4

151

Q6UXC1
SVVVEFDDGDTGHIA

BAHCC1

2011

Q9P281
GQATVLEEDHGLFEI

CRYBG3

2441

Q68DQ2
EDVDGDGVHEITSRD

AHI1

316

Q8N157
VLLHIATEDNIGGEE

AZIN1

151

O14977
TGEVIGHVAEGDRAD

ALDH1B1

61

P30837
GEAVEHGEESKDRTI

RASGRP1

636

O95267
DLVGDESEGLHEVVA

ACTR1B

266

P42025
VDVVDLLLEGGADVD

ANKRD50

761

Q9ULJ7
SGEEEEEQIHSTGLE

BMP4

91

P12644
IGAEDDDFGTEHEQI

ARHGEF12

351

Q9NZN5
HEEEGENEITIGAEP

AMPH

551

P49418
EVEEDLIDAVTGLSG

PYCR1

161

P32322
AELGELSGFEDVHLE

ARHGEF28

1241

Q8N1W1
EIDSLLSQRGDGEHE

FIGNL1

501

Q6PIW4
PTEGELHDLIAEVEE

EFCAB2

186

Q5VUJ9
LHDLIAEVEEEEPTG

EFCAB2

191

Q5VUJ9
EGHTEIVQDLLDAGT

KIDINS220

246

Q9ULH0
GVQIDFDAIIDDGDH

GLI3

1501

P10071
GVVLDGRESTDDHAI

LRP11

226

Q86VZ4
GERASHEEVEGLVEK

LGALS3BP

331

Q08380
GALDFEHIEEQAEGI

ITPR1

1036

Q14643
EHIEEQAEGIFGGSE

ITPR1

1041

Q14643
VEEGINVLASLHGDD

KY

486

Q8NBH2
DEGDVVEVTGHAHVL

MGRN1

206

O60291
GEDDVIEHLYIVEGE

KIAA1109

1471

Q2LD37
TGHADDCVGLELVVE

MTRR

126

Q9UBK8
VAHGALSDGAIDAVE

MCM3AP

1431

O60318
HVHEEEGIVVAVGQD

DCAF4L1

321

Q3SXM0
RESLAEEHEGLVGEG

CPSF1

166

Q10570
EEEAGTEIAIILDGS

ITGAE

196

P38570
VHLESLEGDGEEETL

PCSK7

56

Q16549
VAEAQHAGGVITEED

GGT7

336

Q9UJ14
EGDEVSLLEGEAVEV

NCF1

241

P14598
VVAEHPDASGEEIEE

NSD2

471

O96028
DGAELDVDVVENHDG

FLNC

1686

Q14315
DAVEDLESVGKGAVH

DCD

86

P81605
NGVLTEGEESDVESH

KDM4C

521

Q9H3R0
TNQEDGVIISEHGED

PAXBP1

171

Q9Y5B6
LGNALEGVHVEEEEG

NASP

106

P49321
VEGDEVSLLEGEAVE

NCF1B

241

A6NI72
VEGDEVSLLEGEAVE

NCF1C

216

A8MVU1
CIEHVEEHGLDIDGI

ARHGAP12

676

Q8IWW6
EGQLASEEEEAEHGL

NOL7

21

Q9UMY1
PHAGLEITEESEDVD

OBSCN

7361

Q5VST9
AVPLDEETHAGEDVA

ALPP

446

P05187
EETHAGEDVAVFARG

ALPP

451

P05187
LDGETHAGEDVAVFA

ALPG

446

P10696
PAEETGEVHEEELVA

NTS

71

P30990
ARDFVEILDGGHEDA

CUBN

1676

O60494
FEVHEDIEVGTIIGT

CDH10

391

Q9Y6N8
TIEDALGGVQEAHFD

FBXO11

271

Q86XK2
GDDIDLIVRCEHDGV

EIF3D

366

O15371
EHAVELDTGAPSEEL

GON4L

1351

Q3T8J9
DLIGEESEGIHEVLV

ACTR1A

266

P61163
LHSVEGGECEEEIVR

IFRD2

401

Q12894
LVVVTDGESHDGEEL

ITGA10

271

O75578
TIELEGGLLEDHFET

ERAP2

241

Q6P179
VLDEDSDGISPEEHL

GEN1

646

Q17RS7
GIAVIHGEAQDAESD

PRPSAP2

206

O60256
ALTALEEGEDVVGDI

C2orf81

46

A6NN90
TDVDHDGDFEIVVAG

CRTAC1

61

Q9NQ79
DEVKDREGDVTASHG

FRY

1386

Q5TBA9
LGEDDGVHTVEDASR

EPS8L1

46

Q8TE68
EEGGEAVHEVEVVIK

F10

296

P00742
EDDELGFHSGEVVEV

GRAP2

286

O75791
SEEREGVVVADGDHD

C4orf54

1296

D6RIA3
EILNDTLEGVHSVDG

COL15A1

321

P39059
SELVIDLGEDHSGRE

ZMYND8

711

Q9ULU4
VLEETHEGEAPGCEE

SLC19A3

216

Q9BZV2
VSGGEQVLLHEEAGD

PPRC1

46

Q5VV67
LGVNHIDTEELSAGE

KIFBP

101

Q96EK5
GQTHGEEDVVIDPLE

KIF28P

681

B7ZC32
GEIEQELALARDGHD

CLIP1

386

P30622
EDLEEHGPGQTVSEE

FAM153B

191

P0C7A2
ELHGESTEFVGRAED

MTMR3

36

Q13615
GIHDIIRGSEPEEEA

PIP4K2C

286

Q8TBX8
AHVIASAGTPEEEEE

NYAP1

606

Q6ZVC0
IHVEEVGAEEGAGAA

FAM167A

6

Q96KS9
GADEEEAELRGEHTL

MEGF6

491

O75095
GDGSEATLHGVVDEL

CARS2

476

Q9HA77
EDDTASGEHEVQIEG

SVOP

26

Q8N4V2
VHVGLEAVELDDGAA

SVOP

41

Q8N4V2
EEGHIVDAEAEEGDA

POLR1A

1396

O95602
EHGTLEEVDQDAGTE

SRGAP1

721

Q7Z6B7
HGSCVGVEEEEAPDI

PHF2

31

O75151
QGATDRGHLDEEEVI

PRUNE2

1331

Q8WUY3
RGHLDEEEVIASGVE

PRUNE2

1336

Q8WUY3
DGFHADGDDVLTVTE

AATK

456

Q6ZMQ8
GGEARLITEENEEEH

NBN

246

O60934
ALEENHVGFSLDVGE

NBPF10

1056

Q6P3W6
EIGAEEAEEVGVEHL

PSMD7

161

P51665
HAGVDVVDRGTEFEL

RASGRP3

661

Q8IV61
HGGLDIVIIEQEDDS

SEMG1

431

P04279
AGLEQEDLVEAHGTF

SIRT2

176

Q8IXJ6
VHVFGVEGNSDELDE

THNSL2

186

Q86YJ6
EEEEQDHGVGRTGTV

TAOK1

331

Q7L7X3
GGGIHEYELEVLVDD

MYCBP2

1766

O75592
HVTIDGIEIDAGLEV

MYCBP2

2426

O75592
EVEEDLIDAVTGLSG

PYCR2

161

Q96C36
GTIVVEGHELHDEDI

IARS1

931

P41252
ATGGIESDEEIRHLD

ST18

916

O60284
DTFEGHIIIDGIDIA

ABCC8

1396

Q09428
VLLQAGADLEHESEG

ANKHD1

586

Q8IWZ3
DAPSLEEVEGHVADG

NCAPH

186

Q15003
HENDGDTIEREEVIG

XIRP2

1521

A4UGR9
HPGSGEEAVALVEEL

ZNF197

106

O14709
TAEELHLVADVDPGE

TICRR

386

Q7Z2Z1
AGGIQTVEDEHVAEL

RGS12

1326

O14924
GHLNDDADTVLVVGE

NOD2

286

Q9HC29
IDFGNVDIGEISHEV

SOX10

271

P56693
GEVEALVHEEAEVPT

THTPA

156

Q9BU02
EETNLGHALDEDGVG

STAB2

536

Q8WWQ8
DGLDIDDNIIHFTVG

PKHD1L1

3356

Q86WI1
GLTVEHAIDSFREGE

SART1

256

O43290
SPEVEEGHEAVEGDL

SNX19

326

Q92543
VDEGLDPEEHTADGE

TSHZ3

26

Q63HK5
LDAIIEEVDEDGSGT

TNNC2

56

P02585
TLAGDVHIVRGDFDE

VPS29

51

Q9UBQ0
HVEIENSGEGLRAEA

TASOR2

1791

Q5VWN6
ESGELHGLTTEEEFV

TTR

71

P02766
LIEGEDHVEVNGEVF

PPIP5K2

166

O43314
IVGHEGTDSQADLED

UGGT2

1156

Q9NYU1
GLGLSEEQISEEEAH

VEZT

306

Q9HBM0
VEESGEHVILGTGEL

EFTUD2

621

Q15029
TDDGITLDHGLAAEV

ZNF711

56

Q9Y462
EAGFIDVEAEIHSDG

HIVEP2

261

P31629
VFLGAHGEDVVVEQE

PRR23C

126

Q6ZRP0
HSEVILDDEEEGGIE

WDR87

2171

Q6ZQQ6
RGVHVELAEEDDGEK

WNK4

436

Q96J92
EVEVVEGVAGEEDHH

UBR5

1571

O95071
DIVESEPENDHGVEL

ZFY

266

P08048
FQDEEEHGVEGVESV

nan

61

A6NHS1
LEGAEELENAVSGHV

MYO9B

1431

Q13459
GAHEIEVGVDEEGFI

MYOM3

901

Q5VTT5
HGLVFGDDTDQEAVA

GRIN2A

96

Q12879