Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	non-membrane spanning protein tyrosine kinase activity	BLK YES1 FYN SRC	3.55e-07	46	26	4	GO:0004715
GeneOntologyMolecularFunction	protein tyrosine kinase activity	BLK TIE1 YES1 FYN SRC	1.10e-06	145	26	5	GO:0004713
GeneOntologyMolecularFunction	phospholipase activator activity	FYN SRC	4.06e-04	23	26	2	GO:0016004
GeneOntologyMolecularFunction	lipase activator activity	FYN SRC	5.61e-04	27	26	2	GO:0060229
GeneOntologyMolecularFunction	ephrin receptor binding	FYN SRC	7.89e-04	32	26	2	GO:0046875
GeneOntologyMolecularFunction	phospholipase binding	FYN SRC	7.89e-04	32	26	2	GO:0043274
GeneOntologyMolecularFunction	cell adhesion molecule binding	PLEC BCAM ADAM10 PKP4 SRC	9.31e-04	599	26	5	GO:0050839
GeneOntologyMolecularFunction	protein kinase activity	BLK TIE1 YES1 FYN SRC	9.38e-04	600	26	5	GO:0004672
GeneOntologyMolecularFunction	transmembrane transporter binding	YES1 FYN SRC	1.41e-03	172	26	3	GO:0044325
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	BLK TIE1 YES1 FYN SRC	1.97e-03	709	26	5	GO:0016773
GeneOntologyMolecularFunction	SH2 domain binding	ADAM10 SRC	2.08e-03	52	26	2	GO:0042169
GeneOntologyMolecularFunction	kinase activity	BLK TIE1 YES1 FYN SRC	2.73e-03	764	26	5	GO:0016301
GeneOntologyMolecularFunction	scaffold protein binding	FYN SRC	6.49e-03	93	26	2	GO:0097110
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	BLK TIE1 YES1 FYN SRC	6.53e-03	938	26	5	GO:0016772
GeneOntologyBiologicalProcess	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	YES1 FYN SRC	3.55e-06	25	25	3	GO:0002433
GeneOntologyBiologicalProcess	Fc-gamma receptor signaling pathway involved in phagocytosis	YES1 FYN SRC	3.55e-06	25	25	3	GO:0038096
GeneOntologyBiologicalProcess	cellular response to platelet-derived growth factor stimulus	YES1 FYN SRC	5.05e-06	28	25	3	GO:0036120
GeneOntologyBiologicalProcess	response to platelet-derived growth factor	YES1 FYN SRC	6.91e-06	31	25	3	GO:0036119
GeneOntologyBiologicalProcess	Fc receptor mediated stimulatory signaling pathway	YES1 FYN SRC	1.00e-05	35	25	3	GO:0002431
GeneOntologyBiologicalProcess	negative regulation of inflammatory response to antigenic stimulus	YES1 FYN SRC	1.19e-05	37	25	3	GO:0002862
GeneOntologyBiologicalProcess	Fc-gamma receptor signaling pathway	YES1 FYN SRC	1.40e-05	39	25	3	GO:0038094
GeneOntologyBiologicalProcess	T cell costimulation	YES1 FYN SRC	3.15e-05	51	25	3	GO:0031295
GeneOntologyBiologicalProcess	lymphocyte costimulation	YES1 FYN SRC	3.54e-05	53	25	3	GO:0031294
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	YES1 FYN SRC	3.75e-05	54	25	3	GO:0048013
GeneOntologyBiologicalProcess	regulation of inflammatory response to antigenic stimulus	YES1 FYN SRC	5.40e-05	61	25	3	GO:0002861
GeneOntologyBiologicalProcess	adherens junction organization	PLEC ADAM10 SRC	5.40e-05	61	25	3	GO:0034332
GeneOntologyBiologicalProcess	Fc receptor signaling pathway	YES1 FYN SRC	5.67e-05	62	25	3	GO:0038093
GeneOntologyBiologicalProcess	immune response-activating cell surface receptor signaling pathway	BLK YES1 FYN BTN1A1 SRC	6.20e-05	359	25	5	GO:0002429
GeneOntologyBiologicalProcess	regulation of postsynapse organization	ADAM10 FYN PRICKLE1 CAPRIN2	6.84e-05	185	25	4	GO:0099175
GeneOntologyBiologicalProcess	regulation of vascular permeability	PLEC YES1 SRC	8.51e-05	71	25	3	GO:0043114
GeneOntologyBiologicalProcess	immune response-regulating cell surface receptor signaling pathway	BLK YES1 FYN BTN1A1 SRC	9.50e-05	393	25	5	GO:0002768
GeneOntologyBiologicalProcess	cell junction organization	PLEC ADAM10 FYN PRICKLE1 PKP4 SRC CAPRIN2	1.16e-04	974	25	7	GO:0034330
GeneOntologyBiologicalProcess	leukocyte migration	PLEC YES1 ADAM10 FYN SRC	1.77e-04	449	25	5	GO:0050900
GeneOntologyBiologicalProcess	negative regulation of inflammatory response	YES1 FYN NR1D2 SRC	1.84e-04	239	25	4	GO:0050728
GeneOntologyBiologicalProcess	cell-cell junction organization	PLEC ADAM10 PKP4 SRC	2.05e-04	246	25	4	GO:0045216
GeneOntologyBiologicalProcess	response to mechanical stimulus	MPO PLEC FYN SRC	2.08e-04	247	25	4	GO:0009612
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	BLK TIE1 YES1 FYN PRICKLE1 SRC	2.17e-04	747	25	6	GO:0007169
GeneOntologyBiologicalProcess	cell-cell adhesion	YES1 FYN PRICKLE1 PKP4 BTN1A1 PCDHB15 SRC	2.18e-04	1077	25	7	GO:0098609
GeneOntologyBiologicalProcess	inflammatory response to antigenic stimulus	YES1 FYN SRC	2.57e-04	103	25	3	GO:0002437
GeneOntologyBiologicalProcess	cellular response to fluid shear stress	PLEC SRC	3.51e-04	23	25	2	GO:0071498
GeneOntologyBiologicalProcess	stimulatory C-type lectin receptor signaling pathway	FYN SRC	3.51e-04	23	25	2	GO:0002223
GeneOntologyBiologicalProcess	cellular response to lectin	FYN SRC	3.51e-04	23	25	2	GO:1990858
GeneOntologyBiologicalProcess	response to lectin	FYN SRC	3.51e-04	23	25	2	GO:1990840
GeneOntologyBiologicalProcess	dendritic spine organization	ADAM10 FYN CAPRIN2	3.55e-04	115	25	3	GO:0097061
GeneOntologyBiologicalProcess	cell-substrate junction organization	PLEC PRICKLE1 SRC	3.55e-04	115	25	3	GO:0150115
GeneOntologyBiologicalProcess	immune response-activating signaling pathway	BLK YES1 FYN BTN1A1 SRC	4.63e-04	553	25	5	GO:0002757
GeneOntologyBiologicalProcess	neuron projection organization	ADAM10 FYN CAPRIN2	4.75e-04	127	25	3	GO:0106027
GeneOntologyBiologicalProcess	postsynapse organization	ADAM10 FYN PRICKLE1 CAPRIN2	5.12e-04	313	25	4	GO:0099173
GeneOntologyBiologicalProcess	peptidyl-tyrosine phosphorylation	BLK YES1 FYN SRC	6.03e-04	327	25	4	GO:0018108
GeneOntologyBiologicalProcess	peptidyl-tyrosine modification	BLK YES1 FYN SRC	6.17e-04	329	25	4	GO:0018212
GeneOntologyBiologicalProcess	dendrite development	ADAM10 FYN PRICKLE1 CAPRIN2	6.60e-04	335	25	4	GO:0016358
GeneOntologyBiologicalProcess	regulation of cell adhesion	YES1 ADAM10 FYN PKP4 BTN1A1 SRC	6.88e-04	927	25	6	GO:0030155
GeneOntologyBiologicalProcess	T cell chemotaxis	PLEC ADAM10	7.28e-04	33	25	2	GO:0010818
GeneOntologyBiologicalProcess	immune response-regulating signaling pathway	BLK YES1 FYN BTN1A1 SRC	7.51e-04	615	25	5	GO:0002764
GeneOntologyBiologicalProcess	activation of immune response	BLK YES1 FYN BTN1A1 SRC	7.96e-04	623	25	5	GO:0002253
GeneOntologyBiologicalProcess	negative regulation of defense response	YES1 FYN NR1D2 SRC	8.03e-04	353	25	4	GO:0031348
GeneOntologyBiologicalProcess	response to fluid shear stress	PLEC SRC	8.19e-04	35	25	2	GO:0034405
GeneOntologyBiologicalProcess	cellular response to chemical stress	MPO PLEC FYN SRC	1.03e-03	377	25	4	GO:0062197
GeneOntologyBiologicalProcess	regulation of synapse organization	ADAM10 FYN PRICKLE1 CAPRIN2	1.13e-03	387	25	4	GO:0050807
GeneOntologyBiologicalProcess	regulation of synapse structure or activity	ADAM10 FYN PRICKLE1 CAPRIN2	1.22e-03	395	25	4	GO:0050803
GeneOntologyBiologicalProcess	cellular response to reactive oxygen species	MPO FYN SRC	1.26e-03	178	25	3	GO:0034614
GeneOntologyBiologicalProcess	positive regulation of peptidyl-tyrosine phosphorylation	YES1 FYN SRC	1.59e-03	193	25	3	GO:0050731
GeneOntologyBiologicalProcess	dendrite morphogenesis	ADAM10 FYN CAPRIN2	1.71e-03	198	25	3	GO:0048813
GeneOntologyBiologicalProcess	lymphocyte chemotaxis	PLEC ADAM10	1.87e-03	53	25	2	GO:0048247
GeneOntologyBiologicalProcess	regulation of leukocyte cell-cell adhesion	YES1 FYN BTN1A1 SRC	1.92e-03	447	25	4	GO:1903037
GeneOntologyBiologicalProcess	Wnt signaling pathway, planar cell polarity pathway	ARHGEF19 PRICKLE1	2.01e-03	55	25	2	GO:0060071
GeneOntologyBiologicalProcess	response to electrical stimulus	PRICKLE1 SRC	2.09e-03	56	25	2	GO:0051602
GeneOntologyBiologicalProcess	regulation of T cell activation	YES1 FYN BTN1A1 SRC	2.10e-03	458	25	4	GO:0050863
GeneOntologyBiologicalProcess	response to food	MPO PLEC	2.24e-03	58	25	2	GO:0032094
GeneOntologyBiologicalProcess	extracellular matrix assembly	TIE1 PRICKLE1	2.31e-03	59	25	2	GO:0085029
GeneOntologyBiologicalProcess	antigen receptor-mediated signaling pathway	BLK FYN BTN1A1	2.41e-03	223	25	3	GO:0050851
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	BLK TIE1 YES1 FYN PRICKLE1 SRC	2.46e-03	1186	25	6	GO:0007167
GeneOntologyBiologicalProcess	cell morphogenesis	PLEC ADAM10 FYN PRICKLE1 SRC CAPRIN2	2.54e-03	1194	25	6	GO:0000902
GeneOntologyBiologicalProcess	leukocyte cell-cell adhesion	YES1 FYN BTN1A1 SRC	2.60e-03	486	25	4	GO:0007159
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	ADAM10 FYN PRICKLE1 SRC CAPRIN2	2.67e-03	819	25	5	GO:0120039
GeneOntologyBiologicalProcess	regulation of dendritic spine morphogenesis	ADAM10 CAPRIN2	2.72e-03	64	25	2	GO:0061001
GeneOntologyBiologicalProcess	cell projection morphogenesis	ADAM10 FYN PRICKLE1 SRC CAPRIN2	2.77e-03	826	25	5	GO:0048858
GeneOntologyBiologicalProcess	activated T cell proliferation	FYN BTN1A1	2.80e-03	65	25	2	GO:0050798
GeneOntologyBiologicalProcess	negative regulation of immune response	YES1 FYN SRC	2.93e-03	239	25	3	GO:0050777
GeneOntologyBiologicalProcess	hydrogen peroxide metabolic process	MPO FYN	2.97e-03	67	25	2	GO:0042743
GeneOntologyBiologicalProcess	positive regulation of immune response	BLK YES1 FYN BTN1A1 SRC	3.06e-03	845	25	5	GO:0050778
GeneOntologyBiologicalProcess	negative regulation of response to external stimulus	YES1 FYN NR1D2 SRC	3.07e-03	509	25	4	GO:0032102
GeneOntologyBiologicalProcess	positive regulation of immune system process	BLK YES1 ADAM10 FYN BTN1A1 SRC	3.10e-03	1242	25	6	GO:0002684
GeneOntologyBiologicalProcess	vascular endothelial growth factor receptor signaling pathway	FYN SRC	3.15e-03	69	25	2	GO:0048010
GeneOntologyBiologicalProcess	response to reactive oxygen species	MPO FYN SRC	3.17e-03	246	25	3	GO:0000302
GeneOntologyBiologicalProcess	regulation of inflammatory response	YES1 FYN NR1D2 SRC	3.20e-03	515	25	4	GO:0050727
GeneOntologyBiologicalProcess	Wnt signaling pathway	ARHGEF19 PRICKLE1 SRC CAPRIN2	3.23e-03	516	25	4	GO:0016055
GeneOntologyBiologicalProcess	immune effector process	MPO PLEC YES1 FYN SRC	3.28e-03	859	25	5	GO:0002252
GeneOntologyCellularComponent	postsynaptic specialization	YES1 ADAM10 FYN PRICKLE1 PKP4 SRC	2.26e-05	503	25	6	GO:0099572
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	YES1 FYN SRC	4.02e-05	56	25	3	GO:0099091
GeneOntologyCellularComponent	perinuclear endoplasmic reticulum	ADAM10 FYN	5.47e-04	29	25	2	GO:0097038
GeneOntologyCellularComponent	actin filament	YES1 FYN SRC	6.86e-04	146	25	3	GO:0005884
GeneOntologyCellularComponent	postsynapse	YES1 ADAM10 FYN PRICKLE1 PKP4 SRC	1.05e-03	1018	25	6	GO:0098794
GeneOntologyCellularComponent	focal adhesion	PLEC YES1 ADAM10 SRC	1.60e-03	431	25	4	GO:0005925
GeneOntologyCellularComponent	cell-substrate junction	PLEC YES1 ADAM10 SRC	1.77e-03	443	25	4	GO:0030055
GeneOntologyCellularComponent	postsynaptic density	ADAM10 FYN PRICKLE1 PKP4	1.89e-03	451	25	4	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	ADAM10 FYN PRICKLE1 PKP4	2.31e-03	477	25	4	GO:0032279
GeneOntologyCellularComponent	glutamatergic synapse	YES1 ADAM10 FYN PRICKLE1 SRC	2.49e-03	817	25	5	GO:0098978
GeneOntologyCellularComponent	neuron to neuron synapse	ADAM10 FYN PRICKLE1 PKP4	3.23e-03	523	25	4	GO:0098984
Domain	TyrKc	BLK TIE1 YES1 FYN SRC	1.02e-07	88	25	5	SM00219
Domain	Tyr_kinase_cat_dom	BLK TIE1 YES1 FYN SRC	1.02e-07	88	25	5	IPR020635
Domain	PROTEIN_KINASE_TYR	BLK TIE1 YES1 FYN SRC	1.67e-07	97	25	5	PS00109
Domain	Tyr_kinase_AS	BLK TIE1 YES1 FYN SRC	1.67e-07	97	25	5	IPR008266
Domain	Pkinase_Tyr	BLK TIE1 YES1 FYN SRC	6.91e-07	129	25	5	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	BLK TIE1 YES1 FYN SRC	9.66e-07	138	25	5	IPR001245
Domain	SH3_1	BLK ARHGEF19 YES1 FYN SRC	2.26e-06	164	25	5	PF00018
Domain	SH3	BLK ARHGEF19 YES1 FYN SRC	8.69e-06	216	25	5	PS50002
Domain	SH3	BLK ARHGEF19 YES1 FYN SRC	8.69e-06	216	25	5	SM00326
Domain	SH2	BLK YES1 FYN SRC	9.34e-06	101	25	4	PF00017
Domain	SH3_domain	BLK ARHGEF19 YES1 FYN SRC	9.50e-06	220	25	5	IPR001452
Domain	SH2	BLK YES1 FYN SRC	1.31e-05	110	25	4	SM00252
Domain	SH2	BLK YES1 FYN SRC	1.36e-05	111	25	4	PS50001
Domain	SH2	BLK YES1 FYN SRC	1.41e-05	112	25	4	IPR000980
Domain	-	BLK YES1 FYN SRC	1.41e-05	112	25	4	3.30.505.10
Domain	Protein_kinase_ATP_BS	BLK TIE1 YES1 FYN SRC	1.27e-04	379	25	5	IPR017441
Domain	PROTEIN_KINASE_ATP	BLK TIE1 YES1 FYN SRC	3.10e-04	459	25	5	PS00107
Domain	Prot_kinase_dom	BLK TIE1 YES1 FYN SRC	4.15e-04	489	25	5	IPR000719
Domain	PROTEIN_KINASE_DOM	BLK TIE1 YES1 FYN SRC	4.31e-04	493	25	5	PS50011
Domain	Kinase-like_dom	BLK TIE1 YES1 FYN SRC	6.63e-04	542	25	5	IPR011009
Domain	C2-set_2	BCAM BTN1A1	1.37e-03	41	25	2	PF08205
Domain	CD80_C2-set	BCAM BTN1A1	1.37e-03	41	25	2	IPR013162
Domain	Znf_CCCH	MKRN4P ZC3H12C	2.72e-03	58	25	2	IPR000571
Domain	SPRY	HNRNPUL1 BTN1A1	6.00e-03	87	25	2	SM00449
Domain	SPRY	HNRNPUL1 BTN1A1	6.97e-03	94	25	2	PF00622
Domain	SPRY_dom	HNRNPUL1 BTN1A1	6.97e-03	94	25	2	IPR003877
Domain	B30.2/SPRY	HNRNPUL1 BTN1A1	7.12e-03	95	25	2	IPR001870
Domain	B302_SPRY	HNRNPUL1 BTN1A1	7.12e-03	95	25	2	PS50188
Domain	IG	BCAM TIE1 BTN1A1	1.81e-02	421	25	3	SM00409
Domain	Ig_sub	BCAM TIE1 BTN1A1	1.81e-02	421	25	3	IPR003599
Pathway	PID_GLYPICAN_1PATHWAY	BLK YES1 FYN SRC	4.06e-08	27	19	4	M33
Pathway	PID_EPHRINB_REV_PATHWAY	BLK YES1 FYN SRC	6.32e-08	30	19	4	M257
Pathway	PID_P38_ALPHA_BETA_PATHWAY	BLK YES1 FYN SRC	6.32e-08	30	19	4	M76
Pathway	PID_ALPHA_SYNUCLEIN_PATHWAY	BLK YES1 FYN SRC	8.27e-08	32	19	4	M275
Pathway	PID_EPHA_FWDPATHWAY	BLK YES1 FYN SRC	1.07e-07	34	19	4	M177
Pathway	PID_AMB2_NEUTROPHILS_PATHWAY	BLK YES1 FYN SRC	2.31e-07	41	19	4	M159
Pathway	PID_PI3KCI_PATHWAY	BLK YES1 FYN SRC	4.42e-07	48	19	4	M141
Pathway	REACTOME_PECAM1_INTERACTIONS	YES1 FYN SRC	4.53e-07	12	19	3	MM14835
Pathway	REACTOME_PECAM1_INTERACTIONS	YES1 FYN SRC	4.53e-07	12	19	3	M11773
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	YES1 ADAM10 FYN SRC	5.66e-07	51	19	4	M27311
Pathway	REACTOME_REGULATION_OF_KIT_SIGNALING	YES1 FYN SRC	5.89e-07	13	19	3	MM14565
Pathway	PID_PTP1B_PATHWAY	BLK YES1 FYN SRC	6.12e-07	52	19	4	M50
Pathway	PID_TXA2PATHWAY	BLK YES1 FYN SRC	8.28e-07	56	19	4	M99
Pathway	REACTOME_REGULATION_OF_KIT_SIGNALING	YES1 FYN SRC	1.15e-06	16	19	3	M537
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	PLEC YES1 FYN SRC	1.61e-06	66	19	4	MM15925
Pathway	REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE	YES1 FYN SRC	1.67e-06	18	19	3	MM15023
Pathway	REACTOME_SIGNALING_BY_KIT_IN_DISEASE	YES1 FYN SRC	2.33e-06	20	19	3	M39002
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	YES1 FYN SRC	2.72e-06	21	19	3	M5876
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	YES1 FYN SRC	2.72e-06	21	19	3	MM14996
Pathway	WP_NRF2ARE_REGULATION	YES1 FYN SRC	3.61e-06	23	19	3	M39761
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	YES1 ADAM10 FYN SRC	6.11e-06	92	19	4	M27201
Pathway	REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE	YES1 FYN SRC	7.42e-06	29	19	3	M27309
Pathway	PID_CXCR4_PATHWAY	BLK YES1 FYN SRC	8.51e-06	100	19	4	M124
Pathway	REACTOME_SIGNALING_BY_CSF1_M_CSF_IN_MYELOID_CELLS	YES1 FYN SRC	9.11e-06	31	19	3	M46423
Pathway	PID_NETRIN_PATHWAY	YES1 FYN SRC	1.00e-05	32	19	3	M108
Pathway	REACTOME_CD28_CO_STIMULATION	YES1 FYN SRC	1.10e-05	33	19	3	M11725
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	YES1 FYN SRC	1.21e-05	34	19	3	MM15025
Pathway	REACTOME_CD28_CO_STIMULATION	YES1 FYN SRC	1.21e-05	34	19	3	MM14992
Pathway	REACTOME_EPHB_MEDIATED_FORWARD_SIGNALING	YES1 FYN SRC	1.57e-05	37	19	3	MM15022
Pathway	REACTOME_SIGNALING_BY_SCF_KIT	YES1 FYN SRC	1.57e-05	37	19	3	MM14564
Pathway	REACTOME_EPHB_MEDIATED_FORWARD_SIGNALING	YES1 FYN SRC	2.31e-05	42	19	3	M27308
Pathway	PID_PDGFRB_PATHWAY	BLK YES1 FYN SRC	2.33e-05	129	19	4	M186
Pathway	REACTOME_SIGNALING_BY_SCF_KIT	YES1 FYN SRC	2.48e-05	43	19	3	M508
Pathway	WP_IL11_SIGNALING	YES1 FYN SRC	2.65e-05	44	19	3	M39716
Pathway	REACTOME_SIGNALING_BY_ERBB2	YES1 FYN SRC	2.65e-05	44	19	3	MM14520
Pathway	WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING	YES1 FYN SRC	3.24e-05	47	19	3	M39380
Pathway	REACTOME_FCGR_ACTIVATION	YES1 FYN SRC	3.46e-05	48	19	3	MM17214
Pathway	PID_AJDISS_2PATHWAY	ADAM10 FYN SRC	3.46e-05	48	19	3	M142
Pathway	REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FYN	FYN SRC	3.60e-05	7	19	2	M27912
Pathway	REACTOME_SIGNALING_BY_ERBB2	YES1 FYN SRC	3.91e-05	50	19	3	M553
Pathway	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	FYN SRC	6.16e-05	9	19	2	MM15059
Pathway	PID_FAK_PATHWAY	YES1 FYN SRC	6.43e-05	59	19	3	M281
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	YES1 FYN SRC	8.60e-05	65	19	3	MM14911
Pathway	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY	YES1 FYN SRC	9.00e-05	66	19	3	MM14990
Pathway	REACTOME_FCGR_ACTIVATION	YES1 FYN SRC	1.03e-04	69	19	3	M27108
Pathway	WP_KIT_RECEPTOR_SIGNALING_PATHWAY	YES1 FYN SRC	1.12e-04	71	19	3	MM15947
Pathway	KEGG_ADHERENS_JUNCTION	YES1 FYN SRC	1.22e-04	73	19	3	M638
Pathway	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY	YES1 FYN SRC	1.27e-04	74	19	3	M17386
Pathway	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	FYN SRC	1.55e-04	14	19	2	M889
Pathway	REACTOME_NETRIN_1_SIGNALING	FYN SRC	1.79e-04	15	19	2	MM14965
Pathway	PID_SYNDECAN_3_PATHWAY	FYN SRC	2.31e-04	17	19	2	M251
Pathway	REACTOME_EPHRIN_SIGNALING	FYN SRC	2.60e-04	18	19	2	MM15024
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	YES1 FYN SRC	2.66e-04	95	19	3	M29842
Pathway	REACTOME_EPHRIN_SIGNALING	FYN SRC	2.90e-04	19	19	2	M27310
Pathway	PID_ECADHERIN_KERATINOCYTE_PATHWAY	FYN SRC	3.56e-04	21	19	2	M184
Pathway	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	YES1 FYN	3.56e-04	21	19	2	MM15633
Pathway	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	YES1 FYN	3.91e-04	22	19	2	M903
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	YES1 FYN SRC	4.54e-04	114	19	3	MM14814
Pathway	WP_GASTRIN_SIGNALING	YES1 FYN SRC	4.66e-04	115	19	3	M39866
Pathway	REACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION	YES1 SRC	4.67e-04	24	19	2	M27803
Pathway	REACTOME_PARASITE_INFECTION	YES1 FYN SRC	4.78e-04	116	19	3	M29843
Pathway	REACTOME_SIGNALING_BY_NTRK2_TRKB	FYN SRC	5.07e-04	25	19	2	M27864
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	YES1 FYN SRC	7.28e-04	134	19	3	M29840
Pathway	REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT	YES1 SRC	7.82e-04	31	19	2	M27805
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	YES1 FYN SRC	8.79e-04	143	19	3	M27107
Pathway	REACTOME_CELL_CELL_COMMUNICATION	PLEC FYN SRC	1.11e-03	155	19	3	M522
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	YES1 FYN SRC	1.17e-03	158	19	3	MM14812
Pathway	REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	YES1 FYN	1.37e-03	41	19	2	MM15162
Pathway	WP_IL7_SIGNALING_PATHWAY	BLK FYN	1.50e-03	43	19	2	MM15864
Pathway	REACTOME_NETRIN_1_SIGNALING	FYN SRC	1.57e-03	44	19	2	M875
Pathway	REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	YES1 FYN	1.87e-03	48	19	2	M914
Pathway	WP_FOCAL_ADHESION	BLK FYN SRC	1.90e-03	187	19	3	MM15913
Pathway	WP_IL3_SIGNALING	FYN SRC	1.95e-03	49	19	2	M39722
Pathway	WP_TROP2_REGULATORY_SIGNALING	ADAM10 SRC	1.95e-03	49	19	2	M46458
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	YES1 FYN SRC	2.11e-03	194	19	3	M16312
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	MKRN4P YES1 FYN BTN1A1 SRC	2.18e-03	719	19	5	MM14540
Pathway	WP_NETRINUNC5B_SIGNALING	FYN SRC	2.19e-03	52	19	2	M39782
Pathway	WP_FOCAL_ADHESION	BLK FYN SRC	2.27e-03	199	19	3	M39402
Pathway	REACTOME_SIGNALING_BY_EGFR	ADAM10 SRC	2.28e-03	53	19	2	M27039
Pathway	WP_VEGFAVEGFR2_SIGNALING	EIF3H ADAM10 FYN SRC	2.32e-03	431	19	4	M39729
Pathway	WP_KIT_RECEPTOR_SIGNALING	FYN SRC	2.81e-03	59	19	2	M39350
Pathway	REACTOME_LEISHMANIA_INFECTION	YES1 FYN SRC	2.98e-03	219	19	3	M29836
Pathway	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS	YES1 ADAM10 FYN SRC	3.03e-03	464	19	4	M27547
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	FYN SRC	3.20e-03	63	19	2	M11187
Pathway	WP_RAC1PAK1P38MMP2_PATHWAY	TIE1 SRC	3.72e-03	68	19	2	M39456
Pathway	KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	ADAM10 SRC	3.72e-03	68	19	2	M16848
Pathway	PID_VEGFR1_2_PATHWAY	FYN SRC	3.83e-03	69	19	2	M237
Pathway	PID_CDC42_PATHWAY	YES1 SRC	3.94e-03	70	19	2	M81
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	YES1 FYN PKP4 SRC	4.02e-03	502	19	4	MM14537
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	BLK YES1 FYN BTN1A1 SRC	4.02e-03	828	19	5	M1058
Pathway	WP_AXON_GUIDANCE	FYN SRC	4.16e-03	72	19	2	M48335
Pathway	REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS	MKRN4P FYN SRC	4.43e-03	252	19	3	MM15585
Pathway	REACTOME_SIGNALING_BY_NTRKS	FYN SRC	4.50e-03	75	19	2	MM14652
Pathway	WP_LEPTIN_SIGNALING	FYN SRC	4.62e-03	76	19	2	M39491
Pathway	WP_PROLACTIN_SIGNALING	FYN SRC	4.62e-03	76	19	2	M39601
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	YES1 FYN SRC	4.88e-03	261	19	3	MM15676
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	YES1 ADAM10 FYN SRC	4.95e-03	532	19	4	M27870
Pathway	REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER	FYN SRC	5.49e-03	83	19	2	M27163
Pathway	WP_ACUTE_VIRAL_MYOCARDITIS	FYN SRC	5.75e-03	85	19	2	M39776
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	BLK FYN	5.88e-03	86	19	2	M601
Pubmed	Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.	BLK YES1 FYN SRC	3.68e-12	6	26	4	2404338
Pubmed	The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome.	BLK YES1 FYN SRC	2.44e-10	14	26	4	29568343
Pubmed	Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).	YES1 ADAM10 FYN SRC	3.33e-10	15	26	4	25036101
Pubmed	Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake.	YES1 FYN SRC	3.71e-10	3	26	3	20080640
Pubmed	Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases.	YES1 FYN SRC	3.71e-10	3	26	3	20176789
Pubmed	Src family kinases are required for integrin but not PDGFR signal transduction.	YES1 FYN SRC	3.71e-10	3	26	3	10228160
Pubmed	Localized activation of Src-family protein kinases in the mouse egg.	YES1 FYN SRC	3.71e-10	3	26	3	17449027
Pubmed	Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.	YES1 FYN SRC	3.71e-10	3	26	3	7958873
Pubmed	Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein.	YES1 FYN SRC	3.71e-10	3	26	3	23497302
Pubmed	Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability.	YES1 FYN SRC	3.71e-10	3	26	3	10635317
Pubmed	Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events.	YES1 FYN SRC	3.71e-10	3	26	3	16400523
Pubmed	Requirement of SRC-family tyrosine kinases in fat accumulation.	YES1 FYN SRC	3.71e-10	3	26	3	16262245
Pubmed	FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.	BLK YES1 FYN SRC	9.44e-10	19	26	4	23616926
Pubmed	FAK-dependent regulation of myofibroblast differentiation.	YES1 FYN SRC	1.48e-09	4	26	3	16585062
Pubmed	Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.	YES1 FYN SRC	1.48e-09	4	26	3	25157176
Pubmed	Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells.	YES1 FYN SRC	1.48e-09	4	26	3	7521304
Pubmed	State and role of SRC family kinases in replication of herpes simplex virus 1.	YES1 FYN SRC	1.48e-09	4	26	3	16537602
Pubmed	Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases.	YES1 FYN SRC	1.48e-09	4	26	3	14559149
Pubmed	Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor.	YES1 FYN SRC	1.48e-09	4	26	3	7681396
Pubmed	A unique role for Fyn in CNS myelination.	YES1 FYN SRC	1.48e-09	4	26	3	11245687
Pubmed	Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase.	YES1 FYN SRC	1.48e-09	4	26	3	7537495
Pubmed	Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics.	YES1 FYN SRC	1.48e-09	4	26	3	25080486
Pubmed	Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.	YES1 FYN SRC	1.48e-09	4	26	3	19258394
Pubmed	Palatal adhesion is dependent on Src family kinases and p38MAPK.	YES1 FYN SRC	3.70e-09	5	26	3	25354453
Pubmed	Clustering-induced tyrosine phosphorylation of nephrin by Src family kinases.	YES1 FYN SRC	3.70e-09	5	26	3	12846735
Pubmed	TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling.	YES1 FYN SRC	3.70e-09	5	26	3	18255094
Pubmed	The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements.	YES1 FYN SRC	3.70e-09	5	26	3	17623777
Pubmed	Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.	YES1 FYN SRC	3.70e-09	5	26	3	12509223
Pubmed	Vav2 is required for cell spreading.	YES1 FYN SRC	3.70e-09	5	26	3	11448999
Pubmed	Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.	YES1 FYN SRC	3.70e-09	5	26	3	18194650
Pubmed	Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac.	YES1 FYN SRC	3.70e-09	5	26	3	10844001
Pubmed	Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.	YES1 FYN SRC	3.70e-09	5	26	3	22971575
Pubmed	The protein tyrosine kinase family of the human genome.	BLK TIE1 YES1 FYN SRC	4.33e-09	83	26	5	11114734
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	BLK YES1 FYN SRC	4.96e-09	28	26	4	18067320
Pubmed	Protein tyrosine phosphatase-alpha complexes with the IGF-I receptor and undergoes IGF-I-stimulated tyrosine phosphorylation that mediates cell migration.	YES1 FYN SRC	7.41e-09	6	26	3	19420001
Pubmed	Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation.	YES1 FYN SRC	7.41e-09	6	26	3	9799234
Pubmed	Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor.	YES1 FYN SRC	7.41e-09	6	26	3	20606012
Pubmed	Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis.	YES1 FYN SRC	7.41e-09	6	26	3	10861086
Pubmed	ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzeta-controlled ERK1/2 activity within the nucleus.	YES1 FYN SRC	7.41e-09	6	26	3	16723512
Pubmed	Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells.	YES1 FYN SRC	7.41e-09	6	26	3	1381360
Pubmed	Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors.	YES1 FYN SRC	7.41e-09	6	26	3	12923167
Pubmed	Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development.	YES1 FYN SRC	1.30e-08	7	26	3	12526739
Pubmed	Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.	YES1 FYN SRC	1.30e-08	7	26	3	9632142
Pubmed	Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress.	YES1 FYN SRC	1.30e-08	7	26	3	12538589
Pubmed	CMS: an adapter molecule involved in cytoskeletal rearrangements.	YES1 FYN SRC	1.30e-08	7	26	3	10339567
Pubmed	Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin.	YES1 FYN SRC	1.30e-08	7	26	3	12558988
Pubmed	Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases.	YES1 FYN SRC	1.30e-08	7	26	3	10858437
Pubmed	The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation.	YES1 FYN SRC	1.30e-08	7	26	3	10829062
Pubmed	QM, a putative tumor suppressor, regulates proto-oncogene c-yes.	YES1 FYN SRC	1.30e-08	7	26	3	12138090
Pubmed	Proline-rich sequences that bind to Src homology 3 domains with individual specificities.	BLK YES1 FYN	1.30e-08	7	26	3	7536925
Pubmed	Phosphorylation of SOCS1 Inhibits the SOCS1-p53 Tumor Suppressor Axis.	BLK YES1 SRC	2.07e-08	8	26	3	31101761
Pubmed	Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression.	YES1 FYN SRC	2.07e-08	8	26	3	21829547
Pubmed	Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis.	YES1 FYN SRC	2.07e-08	8	26	3	16921024
Pubmed	p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction.	YES1 FYN SRC	2.07e-08	8	26	3	12640114
Pubmed	Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.	YES1 FYN SRC	2.07e-08	8	26	3	15190072
Pubmed	Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.	YES1 FYN SRC	3.11e-08	9	26	3	18697750
Pubmed	Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.	ADAM10 FYN SRC	4.43e-08	10	26	3	11741929
Pubmed	The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons.	YES1 FYN SRC	4.43e-08	10	26	3	16687575
Pubmed	Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.	YES1 FYN SRC	6.09e-08	11	26	3	11312300
Pubmed	SRC family kinases are required for limb trajectory selection by spinal motor axons.	YES1 FYN SRC	6.09e-08	11	26	3	19403835
Pubmed	JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.	YES1 FYN SRC	6.09e-08	11	26	3	18499741
Pubmed	Absence of Fyn and Src causes a reeler-like phenotype.	YES1 FYN SRC	1.06e-07	13	26	3	16162939
Pubmed	Integrin signalling regulates YAP and TAZ to control skin homeostasis.	YES1 FYN SRC	1.68e-07	15	26	3	26989177
Pubmed	Ouabain stimulates a Na+/K+-ATPase-mediated SFK-activated signalling pathway that regulates tight junction function in the mouse blastocyst.	YES1 SRC	5.37e-07	2	26	2	21901128
Pubmed	Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice.	YES1 SRC	5.37e-07	2	26	2	7507074
Pubmed	Differential effects of the Src family tyrosine kinases Yes and Fyn on lipopolysaccharide-induced lung injury in mice.	YES1 FYN	5.37e-07	2	26	2	34105991
Pubmed	Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.	FYN SRC	5.37e-07	2	26	2	8681387
Pubmed	Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells.	FYN SRC	5.37e-07	2	26	2	22354875
Pubmed	Elevated c-Src and c-Yes expression in malignant skin cancers.	YES1 SRC	5.37e-07	2	26	2	20796316
Pubmed	The p60c-src family of protein-tyrosine kinases: structure, regulation, and function.	YES1 FYN	5.37e-07	2	26	2	1384720
Pubmed	c-Src but not Fyn promotes proper spindle orientation in early prometaphase.	FYN SRC	5.37e-07	2	26	2	22689581
Pubmed	Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke.	FYN SRC	5.37e-07	2	26	2	11175854
Pubmed	The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo.	YES1 SRC	5.37e-07	2	26	2	10549294
Pubmed	Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability.	FYN SRC	5.37e-07	2	26	2	15486073
Pubmed	Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.	YES1 SRC	5.37e-07	2	26	2	21390316
Pubmed	EG-1 interacts with c-Src and activates its signaling pathway.	YES1 FYN SRC	5.66e-07	22	26	3	16964398
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	YES1 FYN SRC	8.44e-07	25	26	3	16374509
Pubmed	Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases.	FYN SRC	1.61e-06	3	26	2	11483655
Pubmed	Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.	FYN SRC	1.61e-06	3	26	2	12089510
Pubmed	H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity.	FYN SRC	1.61e-06	3	26	2	12695509
Pubmed	Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.	FYN SRC	1.61e-06	3	26	2	19690143
Pubmed	Non-receptor tyrosine kinases in mammalian neurogenesis.	FYN SRC	1.61e-06	3	26	2	8983085
Pubmed	Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner.	FYN SRC	1.61e-06	3	26	2	7517401
Pubmed	Regulation of TRPC6 channel activity by tyrosine phosphorylation.	FYN SRC	1.61e-06	3	26	2	14761972
Pubmed	Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn.	YES1 FYN	1.61e-06	3	26	2	8570184
Pubmed	A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation.	FYN SRC	1.61e-06	3	26	2	15297464
Pubmed	Critical roles of Src family tyrosine kinases in excitatory neuronal differentiation of cultured embryonic stem cells.	FYN SRC	1.61e-06	3	26	2	16859680
Pubmed	Disease-related modifications in tau affect the interaction between Fyn and Tau.	FYN SRC	1.61e-06	3	26	2	16115884
Pubmed	Differential transformation capacity of Src family kinases during the initiation of prostate cancer.	FYN SRC	1.61e-06	3	26	2	21464326
Pubmed	Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia.	FYN SRC	1.61e-06	3	26	2	12932824
Pubmed	Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.	BLK FYN	1.61e-06	3	26	2	18579586
Pubmed	Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.	FYN SRC	1.61e-06	3	26	2	7617039
Pubmed	Protein tyrosine phosphatase epsilon activates Yes and Fyn in Neu-induced mammary tumor cells.	YES1 FYN	1.61e-06	3	26	2	14980517
Pubmed	Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer.	FYN SRC	1.61e-06	3	26	2	25053806
Pubmed	Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases.	YES1 FYN	1.61e-06	3	26	2	7685273
Pubmed	Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor.	FYN SRC	1.61e-06	3	26	2	11024032
Pubmed	Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.	FYN SRC	1.61e-06	3	26	2	11353545
Pubmed	Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase.	YES1 FYN	1.61e-06	3	26	2	19258392
Pubmed	Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family.	FYN SRC	3.22e-06	4	26	2	10871840
Pubmed	p21rasGAP association with Fyn, Lyn, and Yes in thrombin-activated platelets.	YES1 FYN	3.22e-06	4	26	2	1544885
Interaction	PECAM1 interactions	FAM120B YES1 FYN SRC	7.64e-08	32	26	4	int:PECAM1
Interaction	EFS interactions	BLK YES1 FYN SRC	1.40e-07	37	26	4	int:EFS
Interaction	SKAP2 interactions	BLK YES1 FYN SRC	5.22e-07	51	26	4	int:SKAP2
Interaction	ACBD7 interactions	YES1 FYN SRC	6.87e-07	14	26	3	int:ACBD7
Interaction	TRPV4 interactions	YES1 FYN SRC	2.89e-06	22	26	3	int:TRPV4
Interaction	NPHS1 interactions	YES1 FYN SRC	7.56e-06	30	26	3	int:NPHS1
Interaction	PRUNE2 interactions	YES1 FYN SRC	9.22e-06	32	26	3	int:PRUNE2
Interaction	ANKRD54 interactions	BLK YES1 SRC	1.01e-05	33	26	3	int:ANKRD54
Interaction	STAP2 interactions	BLK YES1 SRC	1.01e-05	33	26	3	int:STAP2
Interaction	FLACC1 interactions	BLK YES1 FYN	1.11e-05	34	26	3	int:FLACC1
Interaction	PRKCH interactions	PLEC FYN SRC	1.21e-05	35	26	3	int:PRKCH
Interaction	DOK2 interactions	FAM120B YES1 FYN SRC	1.41e-05	116	26	4	int:DOK2
Interaction	CD36 interactions	YES1 FYN SRC	1.69e-05	39	26	3	int:CD36
Interaction	KIT interactions	BLK YES1 FYN SRC	1.90e-05	125	26	4	int:KIT
Interaction	LCK interactions	BLK YES1 ADAM10 FYN PKP4 SRC	2.22e-05	463	26	6	int:LCK
Interaction	PCDHGC3 interactions	YES1 FYN SRC	4.53e-05	54	26	3	int:PCDHGC3
Interaction	SH3BP1 interactions	PLEC FYN SRC	4.78e-05	55	26	3	int:SH3BP1
Interaction	CYFIP2 interactions	PLEC YES1 ADAM10 NHSL2 SRC	5.11e-05	323	26	5	int:CYFIP2
Interaction	DOK1 interactions	YES1 FYN SRC	5.91e-05	59	26	3	int:DOK1
Interaction	PXN interactions	BLK YES1 ADAM10 FYN SRC	5.99e-05	334	26	5	int:PXN
Interaction	IGSF9B interactions	YES1 SRC	7.16e-05	10	26	2	int:IGSF9B
Interaction	PIM3 interactions	YES1 FYN SRC	7.19e-05	63	26	3	int:PIM3
Interaction	SOCS1 interactions	BLK YES1 FYN SRC	7.39e-05	177	26	4	int:SOCS1
Interaction	FGD4 interactions	ARHGEF19 PLEC PRICKLE1	7.54e-05	64	26	3	int:FGD4
Interaction	AIP interactions	BLK YES1 FYN SRC	8.24e-05	182	26	4	int:AIP
Interaction	CDK1 interactions	BLK PLEC HNRNPUL1 YES1 FYN SRC	8.57e-05	590	26	6	int:CDK1
Interaction	ERBB4 interactions	BLK YES1 FYN SRC	8.59e-05	184	26	4	int:ERBB4
Interaction	GAB3 interactions	FYN SRC	8.74e-05	11	26	2	int:GAB3
Interaction	ADAM15 interactions	YES1 FYN SRC	9.44e-05	69	26	3	int:ADAM15
Interaction	PTPRE interactions	YES1 FYN SRC	9.44e-05	69	26	3	int:PTPRE
Interaction	TNK2 interactions	YES1 FYN PKP4 SRC	1.08e-04	195	26	4	int:TNK2
Interaction	PIK3R3 interactions	BLK YES1 FYN SRC	1.14e-04	198	26	4	int:PIK3R3
Interaction	CBLC interactions	YES1 FYN SRC	1.21e-04	75	26	3	int:CBLC
Interaction	CSF1R interactions	YES1 FYN SRC	1.21e-04	75	26	3	int:CSF1R
Interaction	FBXL22 interactions	BLK SRC	1.24e-04	13	26	2	int:FBXL22
Interaction	TBCK interactions	PLEC PCDHB15 SRC	1.58e-04	82	26	3	int:TBCK
Interaction	PIK3R1 interactions	BLK TIE1 YES1 FYN SRC	1.61e-04	412	26	5	int:PIK3R1
Interaction	TMEM185A interactions	YES1 FYN SRC	1.88e-04	87	26	3	int:TMEM185A
Interaction	GP6 interactions	YES1 FYN	1.90e-04	16	26	2	int:GP6
Interaction	SLC25A41 interactions	YES1 FYN SRC	2.08e-04	90	26	3	int:SLC25A41
Interaction	DLG4 interactions	YES1 ADAM10 FYN PRICKLE1 SRC	2.40e-04	449	26	5	int:DLG4
Interaction	CTTN interactions	PLEC EIF3H YES1 NHSL2 SRC	2.42e-04	450	26	5	int:CTTN
Interaction	TP53BP2 interactions	PLEC HNRNPUL1 YES1 NHSL2	2.42e-04	241	26	4	int:TP53BP2
Interaction	HSP90AB3P interactions	BLK YES1 FYN	2.67e-04	98	26	3	int:HSP90AB3P
Interaction	TAMALIN interactions	FYN SRC	2.70e-04	19	26	2	int:TAMALIN
Interaction	CERS2 interactions	PLEC YES1 FYN SRC	2.75e-04	249	26	4	int:CERS2
Interaction	MAP2 interactions	PLEC FYN SRC	3.18e-04	104	26	3	int:MAP2
Interaction	FASLG interactions	YES1 FYN SRC	3.27e-04	105	26	3	int:FASLG
Interaction	PEX2 interactions	YES1 SRC	3.31e-04	21	26	2	int:PEX2
Interaction	CCNL2 interactions	YES1 FYN SRC	3.37e-04	106	26	3	int:CCNL2
Interaction	DAB1 interactions	YES1 FYN SRC	3.46e-04	107	26	3	int:DAB1
Interaction	CTNND1 interactions	BLK YES1 FYN SRC	3.48e-04	265	26	4	int:CTNND1
Interaction	SPRR2A interactions	YES1 SRC	3.64e-04	22	26	2	int:SPRR2A
Interaction	CDH8 interactions	BCAM PKP4	3.64e-04	22	26	2	int:CDH8
Interaction	EPHA3 interactions	ADAM10 FYN SRC	3.86e-04	111	26	3	int:EPHA3
Interaction	HOXB5 interactions	YES1 FYN SRC	3.96e-04	112	26	3	int:HOXB5
Interaction	SPR interactions	YES1 FYN SRC	4.06e-04	113	26	3	int:SPR
Interaction	MED28 interactions	YES1 FYN SRC	4.39e-04	116	26	3	int:MED28
Interaction	SOS1 interactions	FYN PRICKLE1 SRC	4.50e-04	117	26	3	int:SOS1
Interaction	FLOT2 interactions	YES1 FYN TCEAL5 SRC	4.58e-04	285	26	4	int:FLOT2
Interaction	ITGB4 interactions	PLEC YES1 FYN	5.46e-04	125	26	3	int:ITGB4
Interaction	TRAT1 interactions	FYN SRC	5.51e-04	27	26	2	int:TRAT1
Interaction	FYB1 interactions	FYN SRC	7.27e-04	31	26	2	int:FYB1
Interaction	SLC14A1 interactions	YES1 SRC	8.25e-04	33	26	2	int:SLC14A1
Interaction	IL1R1 interactions	YES1 SRC	8.75e-04	34	26	2	int:IL1R1
Interaction	ARHGAP32 interactions	B4GALT2 FYN SRC	9.09e-04	149	26	3	int:ARHGAP32
Interaction	KDR interactions	YES1 FYN SRC	9.27e-04	150	26	3	int:KDR
Interaction	FYTTD1 interactions	ARHGEF19 YES1 SRC	1.00e-03	154	26	3	int:FYTTD1
Interaction	FAS interactions	EIF3H YES1 FYN SRC	1.01e-03	352	26	4	int:FAS
Interaction	ANKRD12 interactions	YES1 FYN	1.04e-03	37	26	2	int:ANKRD12
Interaction	CD46 interactions	YES1 SRC	1.04e-03	37	26	2	int:CD46
Interaction	MED21 interactions	YES1 FYN SRC	1.10e-03	159	26	3	int:MED21
Interaction	TYRO3 interactions	YES1 FYN SRC	1.12e-03	160	26	3	int:TYRO3
Interaction	WBP11 interactions	ARHGEF19 FYN SRC	1.12e-03	160	26	3	int:WBP11
Interaction	GRB10 interactions	BLK FYN SRC	1.14e-03	161	26	3	int:GRB10
Interaction	PRRG4 interactions	FYN SRC	1.15e-03	39	26	2	int:PRRG4
Interaction	PTPRZ1 interactions	ADAM10 FYN	1.15e-03	39	26	2	int:PTPRZ1
Interaction	HSP90AB1 interactions	BLK EIF3H HNRNPUL1 YES1 FYN SRC	1.17e-03	960	26	6	int:HSP90AB1
Interaction	PTPN11 interactions	TIE1 ADAM10 FYN SRC	1.19e-03	368	26	4	int:PTPN11
Interaction	SRCIN1 interactions	ADAM10 SRC	1.21e-03	40	26	2	int:SRCIN1
Interaction	SRMS interactions	BLK SRC	1.21e-03	40	26	2	int:SRMS
Interaction	JAK2 interactions	YES1 FYN SRC	1.22e-03	165	26	3	int:JAK2
Interaction	KHDRBS1 interactions	PLEC YES1 FYN SRC	1.25e-03	373	26	4	int:KHDRBS1
Interaction	JAKMIP1 interactions	BLK YES1	1.40e-03	43	26	2	int:JAKMIP1
Interaction	CD244 interactions	FYN SRC	1.40e-03	43	26	2	int:CD244
Interaction	DIAPH1 interactions	YES1 FYN SRC	1.47e-03	176	26	3	int:DIAPH1
Interaction	GAB1 interactions	BLK YES1 SRC	1.52e-03	178	26	3	int:GAB1
Interaction	RORC interactions	NR1D2 SRC	1.53e-03	45	26	2	int:RORC
Interaction	FXR1 interactions	BLK HNRNPUL1 YES1 ADAM10 CAPRIN2	1.56e-03	679	26	5	int:FXR1
Interaction	IVNS1ABP interactions	HNRNPUL1 FYN PRICKLE1	1.57e-03	180	26	3	int:IVNS1ABP
Interaction	FLRT1 interactions	YES1 PKP4	1.60e-03	46	26	2	int:FLRT1
Interaction	PRKD1 interactions	PLEC YES1 SRC	1.67e-03	184	26	3	int:PRKD1
Interaction	SH3BP2 interactions	FYN SRC	1.74e-03	48	26	2	int:SH3BP2
Interaction	C5orf24 interactions	ARHGEF19 PCDHB15	1.74e-03	48	26	2	int:C5orf24
Interaction	MEOX2 interactions	B4GALT2 FYN NR1D2 BTN1A1 CAPRIN2	1.75e-03	697	26	5	int:MEOX2
Interaction	EPHA4 interactions	FYN PKP4 SRC	1.77e-03	188	26	3	int:EPHA4
Interaction	SPHK1 interactions	FYN SRC	1.81e-03	49	26	2	int:SPHK1
Interaction	NCSTN interactions	BLK YES1 SRC	1.88e-03	192	26	3	int:NCSTN
Interaction	FRK interactions	BLK FYN	1.89e-03	50	26	2	int:FRK
Interaction	HCK interactions	BLK YES1 SRC	1.91e-03	193	26	3	int:HCK
Cytoband	1p34-p33	B4GALT2 TIE1	1.85e-06	4	26	2	1p34-p33
Cytoband	19q13.2	BCAM HNRNPUL1	3.90e-03	164	26	2	19q13.2
GeneFamily	SH2 domain containing	BLK YES1 FYN SRC	4.15e-06	101	20	4	741
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	BCAM BTN1A1	8.84e-04	40	20	2	592
GeneFamily	Immunoglobulin like domain containing	BCAM TIE1	1.90e-02	193	20	2	594
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2 PKP4	3.61e-06	182	26	4	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	facs-Lung-Endomucin-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC BCAM ADAM10 PRICKLE1	3.85e-06	185	26	4	f262b441ea3fe7f69dff33d5f171000371f3a3e5
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM HNRNPUL1 TIE1 YES1	3.94e-06	186	26	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2 PKP4	4.11e-06	188	26	4	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 YES1 PKP4	4.19e-06	189	26	4	476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 YES1 PKP4	4.19e-06	189	26	4	3fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 YES1 PKP4	4.19e-06	189	26	4	d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1 PKP4	4.65e-06	194	26	4	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1 PKP4	4.65e-06	194	26	4	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2 PKP4	5.14e-06	199	26	4	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2 PKP4	5.14e-06	199	26	4	f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2 PKP4	5.25e-06	200	26	4	90061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell	facs-Spleen-nan-24m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK MPO PRICKLE1	1.23e-04	167	26	3	9a8e291c082d7c26bab21df77bd36ce927032a70
ToppCell	facs-Heart-LV-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO BCAM TIE1	1.27e-04	169	26	3	6a31a940a8474fb087d8fe7193a6974a72e0a014
ToppCell	facs-Heart-LV-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO BCAM TIE1	1.27e-04	169	26	3	39d627763abd57e53edb1169832b47cfb3e8c274
ToppCell	facs-Heart-LV-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO BCAM TIE1	1.27e-04	169	26	3	b85927a256790402e9fc12ebcadd83e4e2afd2ce
ToppCell	facs\|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC ADAM10 PRICKLE1	1.32e-04	171	26	3	5bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCell	facs\|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLEC ADAM10 PRICKLE1	1.32e-04	171	26	3	bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 PKP4	1.32e-04	171	26	3	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TIE1 YES1 NHSL2	1.32e-04	171	26	3	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	10x5'-Lung-Lymphocytic_B-Memory_B_cells\|Lung / Manually curated celltypes from each tissue	BLK PRICKLE1 BTN1A1	1.34e-04	172	26	3	2cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PCDHB15	1.38e-04	174	26	3	40bb87d219aafab0357ab0d797efd38085fc0312
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD4_TEM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	HNRNPUL1 FYN NHSL2	1.38e-04	174	26	3	d2ea5b55bf03a8013816d073896208f311c3e544
ToppCell	IPF-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	TIE1 YES1 FYN	1.41e-04	175	26	3	b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	BLK PRICKLE1 PKP4	1.41e-04	175	26	3	69ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCell	facs-Heart-RV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.43e-04	176	26	3	fb3d03f64592e1df1d9785d9f2e70938d7ff9ce8
ToppCell	facs-Heart-RV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.43e-04	176	26	3	3270a36fc91a5583646ffeb70bfcbc5af7292aac
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLEC TIE1 NHSL2	1.43e-04	176	26	3	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	facs-Heart-RV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.43e-04	176	26	3	99410c121f55adbc7fcc013c8fa8905a45dba76b
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLEC TIE1 NHSL2	1.43e-04	176	26	3	96779273b94345250cf53ba671203345b43d9e00
ToppCell	facs-Heart-LV\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO BCAM TIE1	1.43e-04	176	26	3	483e36d9bb7268bf179e69a65e1a0be099035162
ToppCell	facs-Aorta-Heart-24m-Endothelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.46e-04	177	26	3	c6b955765aee8a196fcf4f7bb16139c95b76dc4e
ToppCell	droplet-Fat-Gat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 PKP4 TCEAL5	1.51e-04	179	26	3	08cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PKP4	1.53e-04	180	26	3	fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 FYN PRICKLE1	1.53e-04	180	26	3	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PKP4	1.53e-04	180	26	3	c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PKP4	1.53e-04	180	26	3	178648429686e6d4e6f3aafc350130e819788ecf
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1	1.53e-04	180	26	3	30cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 FYN PRICKLE1	1.53e-04	180	26	3	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 PRICKLE1 NHSL2	1.56e-04	181	26	3	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 PRICKLE1 NHSL2	1.56e-04	181	26	3	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.56e-04	181	26	3	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 FYN PRICKLE1	1.58e-04	182	26	3	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC BCAM TIE1	1.58e-04	182	26	3	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC BCAM TIE1	1.58e-04	182	26	3	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 FYN PRICKLE1	1.58e-04	182	26	3	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC BCAM TIE1	1.58e-04	182	26	3	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1	1.61e-04	183	26	3	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	facs-Lung-Endomucin-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM ADAM10 PRICKLE1	1.61e-04	183	26	3	3dc6cbe803e5b8c4201faaf2e6445898d71684e6
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 PKP4	1.63e-04	184	26	3	df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 PKP4	1.63e-04	184	26	3	1ace70f12b417185bdd46042833f72b3b6815966
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEC BCAM PRICKLE1	1.63e-04	184	26	3	af5eb3650fafc808828eb42f68c0f1e9c278adbb
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.66e-04	185	26	3	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	facs-Heart-RV\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.66e-04	185	26	3	7cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1	1.71e-04	187	26	3	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	facs-Aorta-Heart-3m-Endothelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.71e-04	187	26	3	df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	TIE1 FYN PRICKLE1	1.71e-04	187	26	3	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	facs-Heart-LV-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.71e-04	187	26	3	1bc338c22d645a854f8d8eb8a064c441121fb673
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.71e-04	187	26	3	d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.71e-04	187	26	3	d6765854154557794815514c0aa355bc74b8523e
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-\|lymph-node_spleen / Manually curated celltypes from each tissue	TIE1 YES1 FYN	1.71e-04	187	26	3	9000241566f48e435db9409b7255db68b68f6059
ToppCell	droplet-Fat-SCAT-30m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.74e-04	188	26	3	e901a9bdf00b8e91806f445af66647373bf62661
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 YES1 PKP4	1.74e-04	188	26	3	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PRICKLE1	1.74e-04	188	26	3	db0652f000d459493321b53239326706eace598c
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 YES1 PKP4	1.74e-04	188	26	3	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	droplet-Fat-SCAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.74e-04	188	26	3	5cf060bb8adaefa9964187195d67993c1248ef47
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1	1.74e-04	188	26	3	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BCAM PRICKLE1 NHSL2	1.74e-04	188	26	3	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BCAM PRICKLE1 NHSL2	1.74e-04	188	26	3	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.74e-04	188	26	3	a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell	droplet-Fat-Scat-21m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.74e-04	188	26	3	8671fdbc4138e6f9559920779c98628ed80f0da3
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 YES1 PKP4	1.74e-04	188	26	3	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	droplet-Fat-SCAT-30m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.74e-04	188	26	3	449f9602df3c83b2110eb479a00d428d1b55b423
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 NHSL2	1.74e-04	188	26	3	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 YES1 PKP4	1.74e-04	188	26	3	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 YES1 PKP4	1.74e-04	188	26	3	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BCAM TIE1 YES1	1.77e-04	189	26	3	f44ddb6cdbb406b0528a9b0ba3811183ab6d1fc6
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 YES1	1.77e-04	189	26	3	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	a3f6ebd1622d36d114e42f6e0618d7b2fe8b9a2f
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCAM TIE1 PKP4	1.77e-04	189	26	3	fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZC3H12C TIE1 YES1	1.77e-04	189	26	3	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	facs-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	d86455cf20769d70d62e2c1dd92cbc93c67aada5
ToppCell	facs-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	5559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCell	facs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 YES1	1.77e-04	189	26	3	1be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	bec57459ad4bab15b2532b57722549fec2e771fb
ToppCell	facs-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCell	facs-Heart-LV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	d424d2554595b2304219f7324406b401711af7c2
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.77e-04	189	26	3	84036d1257f6b18f47cfc7ac5e6ed6ea3553c235
ToppCell	droplet-Fat-Scat-21m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCell	facs-GAT-Fat-24m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCell	facs-GAT-Fat-24m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCell	droplet-Fat-Scat-21m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCell	facs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	89d1d686cc683206534e2157554d7d0df5d53497
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TIE1 FYN PKP4	1.79e-04	190	26	3	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	5174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCell	facs-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCAM TIE1 PRICKLE1	1.79e-04	190	26	3	d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCell	facs-GAT-Fat-24m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAM TIE1 PKP4	1.79e-04	190	26	3	3395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
Drug	Dasatinib	YES1 FYN SRC	1.58e-07	10	26	3	DB01254
Drug	ponatinib	BLK YES1 FYN SRC	1.04e-06	68	26	4	ctd:C545373
Drug	1-methyl-1H-indole-2-carboxylic acid	FYN SRC	7.51e-06	4	26	2	CID000027695
Drug	polyproline	ARHGEF19 PLEC YES1 FYN SRC	1.86e-05	295	26	5	CID000439587
Drug	chromium	MPO BCAM YES1 FYN SRC	3.61e-05	339	26	5	CID000023976
Drug	lavendustin A	BLK YES1 FYN SRC	4.04e-05	171	26	4	CID000003894
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A	B4GALT2 MPO SRC CAPRIN2	6.60e-05	194	26	4	3184_DN
Drug	Glibenclamide [10238-21-8]; Down 200; 8uM; MCF7; HT_HG-U133A	MPO ADAM10 FYN CAPRIN2	6.73e-05	195	26	4	3163_DN
Drug	trichostatin A; Up 200; 0.1uM; HL60; HG-U133A	TP53I3 PLEC BCAM FYN	6.73e-05	195	26	4	364_UP
Drug	Free Radicals	MPO FYN	6.85e-05	11	26	2	ctd:D005609
Drug	dasatinib	YES1 FYN SRC	6.88e-05	70	26	3	CID003062316
Drug	imatinib	BLK TIE1 YES1 FYN SRC	1.11e-04	430	26	5	CID000005291
Drug	PD173952	FYN SRC	1.30e-04	15	26	2	CID005328733
Drug	PD173956	FYN SRC	1.30e-04	15	26	2	CID005330524
Drug	EKB-569	YES1 FYN SRC	1.31e-04	87	26	3	CID006445562
Drug	AC1L8YWB	MPO BTN1A1	1.49e-04	16	26	2	CID000435142
Drug	camonagrel	MPO BCAM	1.69e-04	17	26	2	CID000065892
Drug	Amifostine	MPO TP53I3	1.69e-04	17	26	2	ctd:D004999
Drug	vandetanib	YES1 FYN SRC	1.93e-04	99	26	3	CID003081361
Drug	phorbol 12-myristate	MPO TP53I3 ADAM10 SRC	2.07e-04	261	26	4	CID000107854
Drug	lariat	MPO PLEC ADAM10	2.29e-04	105	26	3	CID000165706
Drug	diphenol	PLEC BCAM	2.35e-04	20	26	2	CID000033665
Drug	hydroxypyridinone	MPO BCAM	2.60e-04	21	26	2	CID000069975
Drug	rhombic	MPO TP53I3 PLEC	2.77e-04	112	26	3	CID000018879
Drug	IN1076	YES1 FYN SRC	2.77e-04	112	26	3	CID000005309
Drug	NSC119914	PLEC ADAM10	2.86e-04	22	26	2	CID000274126
Drug	Fe(III	MPO TP53I3 PLEC BCAM TIE1	3.13e-04	537	26	5	CID000023925
Drug	6-methoxypurine arabinoside	FYN SRC	3.41e-04	24	26	2	CID000124757
Drug	anabaseine	MPO BTN1A1	3.41e-04	24	26	2	CID000018985
Drug	1,1-dimethylbutyl-1-deoxy-Delta(9)-THC	MPO TIE1	3.70e-04	25	26	2	ctd:C432747
Drug	VX-745	YES1 SRC	3.70e-04	25	26	2	CID003038525
Drug	myristate	MPO YES1 FYN SRC	3.98e-04	310	26	4	CID000011005
Drug	sunitinib	YES1 FYN SRC	4.30e-04	130	26	3	CID005329102
Drug	G 3012	YES1 FYN SRC	4.49e-04	132	26	3	CID000120739
Drug	HU 211	MPO SRC	4.65e-04	28	26	2	ctd:C062018
Drug	selva	FYN SRC	4.65e-04	28	26	2	CID000010157
Drug	AHTN	PLEC YES1	5.00e-04	29	26	2	CID000089440
Drug	AC1NRA8W	FYN SRC	5.00e-04	29	26	2	CID005287760
Drug	PCB 47	MPO PLEC	5.71e-04	31	26	2	CID000017097
Drug	atremon	FYN SRC	6.48e-04	33	26	2	CID000002741
Drug	sodium acetylacetonate	BCAM BTN1A1	6.48e-04	33	26	2	CID000018630
Drug	Fluorouracil	TP53I3 EIF3H YES1 ADAM10 FYN NR1D2 SRC	6.54e-04	1364	26	7	ctd:D005472
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A	MPO PLEC ADAM10	7.86e-04	160	26	3	6133_DN
Drug	Cgp77675	YES1 SRC	1.10e-03	43	26	2	CID005311381
Drug	fullerene C60	B4GALT2 FAM120B BCAM TIE1 YES1 NR1D2 SRC	1.14e-03	1498	26	7	ctd:C069837
Disease	colorectal cancer (implicated_via_orthology)	BLK YES1 FYN SRC	1.08e-08	30	25	4	DOID:9256 (implicated_via_orthology)
Disease	intestinal cancer (implicated_via_orthology)	BLK YES1 FYN SRC	1.42e-08	32	25	4	DOID:10155 (implicated_via_orthology)
Disease	kidney disease (implicated_via_orthology)	BLK YES1 FYN SRC	3.97e-08	41	25	4	DOID:557 (implicated_via_orthology)
Disease	carcinoma (implicated_via_orthology)	BLK YES1 FYN SRC	2.46e-07	64	25	4	DOID:305 (implicated_via_orthology)
Disease	cancer (implicated_via_orthology)	BLK YES1 FYN SRC	7.24e-05	268	25	4	DOID:162 (implicated_via_orthology)
Disease	Colitis	MPO SRC	2.04e-04	25	25	2	C0009319
Disease	white matter microstructure measurement	PLEC TIE1 FYN ICA1L	3.05e-04	390	25	4	EFO_0005674
Disease	Alcoholic Intoxication	MPO FYN	3.37e-04	32	25	2	C0001969
Disease	cholesteryl esters to total lipids in small HDL percentage	BCAM ADAM10	6.09e-04	43	25	2	EFO_0022254
Disease	free cholesterol to total lipids in small HDL percentage	BCAM ADAM10	8.57e-04	51	25	2	EFO_0022285
Disease	family history of Alzheimer’s disease	BCAM ADAM10	1.65e-03	71	25	2	EFO_0009268
Disease	mean fractional anisotropy measurement	PLEC TIE1	2.93e-03	95	25	2	EFO_0008399
Disease	Acute Confusional Senile Dementia	MPO ADAM10	3.18e-03	99	25	2	C0546126
Disease	Presenile dementia	MPO ADAM10	3.18e-03	99	25	2	C0011265
Disease	Alzheimer's Disease, Focal Onset	MPO ADAM10	3.18e-03	99	25	2	C0750900
Disease	Alzheimer Disease, Early Onset	MPO ADAM10	3.18e-03	99	25	2	C0750901
Disease	Alzheimer Disease, Late Onset	MPO ADAM10	3.18e-03	99	25	2	C0494463
Disease	Familial Alzheimer Disease (FAD)	MPO ADAM10	3.24e-03	100	25	2	C0276496
Disease	Alzheimer's Disease	MPO ADAM10	3.31e-03	101	25	2	C0002395

Protein segments in the cluster

Peptide	Gene	Start	Entry
RDPRSEYDRTQPPMQ	PKP4	1056	Q99569
PMDDRNLYRCGDQPR	B4GALT2	221	O60909
RQQENMQRQSRGEPP	EIF3H	281	O15372
REQEAEQMPEYRGRA	BTN1A1	81	Q13410
QPQRQRPRESYQMGH	ADAM10	731	O14672
MYPDGRREEPQRQQV	MKRN4P	426	Q13434
RADLMQRQGQYDPPP	TP53I3	41	Q53FA7
MRVYQREEVPGCPEA	ARHGEF19	141	Q8IW93
RLDNRYQPMEPNPRV	MPO	511	P05164
MEPAGERFPEQRQVL	PCDHB15	1	Q9Y5E8
GNYDIEIRQPPMSER	PRICKLE1	641	Q96MT3
LEQVERGYRMPCPQD	FYN	476	P06241
YPGMSNPEVIRNLER	BLK	436	P51451
NPEVIRNLERGYRMP	BLK	441	P51451
QPEIQPQEFLNRRYM	CAPRIN2	361	Q6IMN6
QPRPEDNQSVVRRMQ	ICA1L	6	Q8NDH6
YRNGQRLEVPVEMNP	BCAM	186	P50895
RQEVPMYTGSEPRQE	FAM120B	446	Q96EK7
RRPLEMEQQQAYRPE	HNRNPUL1	126	Q9BUJ2
PQRGERIPKNMEQYN	NR1D2	281	Q14995
NREVLDQVERGYRMP	SRC	471	P12931
GYPERLIQQRHMPER	NHSL2	456	Q5HYW2
LPQGYRMEQPRNCDD	TIE1	1066	P35590
MQRDVQDPFAPRGQR	TCEAL5	171	Q5H9L2
YDAMPRVPDVQDGVR	PLEC	396	Q15149
GMPQDPPRYQDNREK	ZC3H12C	826	Q9C0D7
VLEQVERGYRMPCPQ	YES1	481	P07947