Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	PRMT6 SOX4 RHOXF2B MSC FOXL2 MNX1 RHOXF2 DNAJB6 PDX1 PRDM13 FOXA1 YY1 PDCD4 HNRNPU ZNF503	3.56e-07	1399	48	15	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	PRMT6 SOX4 RHOXF2B MSC FOXL2 MNX1 RHOXF2 DNAJB6 PDX1 PRDM13 FOXA1 YY1 PDCD4 HNRNPU ZNF503	4.04e-07	1413	48	15	GO:1902679
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	PRMT6 SOX4 RHOXF2B MSC FOXL2 MNX1 RHOXF2 PDX1 PRDM13 FOXA1 YY1 HNRNPU	3.72e-06	1053	48	12	GO:0000122
GeneOntologyBiologicalProcess	endocrine pancreas development	SOX4 MNX1 PDX1 GDF11	1.22e-05	61	48	4	GO:0031018
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	SOX4 NPPC H4C1 INHBA FOXA1 YY1 GDF11 PDCD4 HNRNPU SYNGAP1	2.70e-05	875	48	10	GO:0045596
GeneOntologyBiologicalProcess	cardiac fibroblast cell differentiation	INHBA PDCD4	7.91e-05	6	48	2	GO:0060935
GeneOntologyBiologicalProcess	cardiac fibroblast cell development	INHBA PDCD4	7.91e-05	6	48	2	GO:0060936
GeneOntologyBiologicalProcess	pancreas development	SOX4 MNX1 PDX1 GDF11	9.28e-05	102	48	4	GO:0031016
GeneOntologyBiologicalProcess	roof of mouth development	COL11A2 MSC INHBA GDF11	1.00e-04	104	48	4	GO:0060021
GeneOntologyBiologicalProcess	positive regulation of follicle-stimulating hormone secretion	FOXL2 INHBA	1.11e-04	7	48	2	GO:0046881
GeneOntologyBiologicalProcess	positive regulation of gonadotropin secretion	FOXL2 INHBA	1.47e-04	8	48	2	GO:0032278
GeneOntologyBiologicalProcess	regulation of follicle-stimulating hormone secretion	FOXL2 INHBA	1.89e-04	9	48	2	GO:0046880
GeneOntologyBiologicalProcess	cardiac cell development	INHBA YY1 PDCD4 HNRNPU	2.51e-04	132	48	4	GO:0055006
GeneOntologyBiologicalProcess	follicle-stimulating hormone secretion	FOXL2 INHBA	2.88e-04	11	48	2	GO:0046884
GeneOntologyBiologicalProcess	response to oxygen-glucose deprivation	NPPC INHBA	2.88e-04	11	48	2	GO:0090649
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	SOX4 NPPC FOXL2 INHBA PDX1 CLASP2	3.33e-04	404	48	6	GO:1903532
GeneOntologyBiologicalProcess	diaphragm development	MSC MNX1	3.45e-04	12	48	2	GO:0060539
GeneOntologyBiologicalProcess	negative regulation of developmental process	SOX4 NPPC H4C1 INHBA FOXA1 YY1 GDF11 PDCD4 HNRNPU SYNGAP1	4.20e-04	1220	48	10	GO:0051093
GeneOntologyBiologicalProcess	positive regulation of secretion	SOX4 NPPC FOXL2 INHBA PDX1 CLASP2	4.93e-04	435	48	6	GO:0051047
GeneOntologyBiologicalProcess	endocrine system development	SOX4 MNX1 PDX1 GDF11	5.33e-04	161	48	4	GO:0035270
GeneOntologyBiologicalProcess	columnar/cuboidal epithelial cell differentiation	SOX4 PDX1 FOXA1 GDF11	5.71e-04	164	48	4	GO:0002065
GeneOntologyBiologicalProcess	animal organ morphogenesis	SOX4 NPPC COL11A2 FOXL2 INHBA PDX1 FOXA1 YY1 GDF11 PDCD4	5.73e-04	1269	48	10	GO:0009887
GeneOntologyCellularComponent	chromatin	SOX4 RHOXF2B MSC FOXL2 MNX1 H4C1 RHOXF2 ZBTB22 PDX1 POGZ FOXA1 EN2 YY1	1.98e-05	1480	48	13	GO:0000785
MousePheno	lethality during fetal growth through weaning, complete penetrance	SOX4 ZSWIM8 NPPC MNX1 INHBA AMOTL1 AFG3L2 PDX1 FOXA1 YY1 GDF11 SOCS7 ZNF503 SYNGAP1	5.82e-06	1269	40	14	MP:0011111
MousePheno	abnormal pancreatic islet size	MNX1 PDX1 GDF11 SOCS7	1.18e-04	89	40	4	MP:0009170
MousePheno	abnormal pancreas development	MNX1 PDX1 GDF11	1.33e-04	35	40	3	MP:0003934
MousePheno	abnormal pancreatic alpha cell mass	PDX1 GDF11	2.21e-04	8	40	2	MP:0030587
MousePheno	abnormal pancreatic beta cell physiology	SOX4 GJD2 MNX1 PDX1 FOXA1	2.27e-04	196	40	5	MP:0003562
MousePheno	abnormal endocrine pancreas physiology	SOX4 GJD2 MNX1 PDX1 FOXA1	2.62e-04	202	40	5	MP:0010147
MousePheno	decreased insulin secretion	SOX4 GJD2 PDX1 FOXA1	2.76e-04	111	40	4	MP:0003059
MousePheno	small pancreatic islets	MNX1 PDX1 GDF11	3.03e-04	46	40	3	MP:0009172
MousePheno	abnormal pancreatic beta cell differentiation	PDX1 GDF11	3.54e-04	10	40	2	MP:0009175
Domain	-	RHOXF2B MNX1 RHOXF2 PDX1 POGZ EN2	7.31e-05	283	47	6	1.10.10.60
Domain	Homeobox_CS	RHOXF2B MNX1 RHOXF2 PDX1 EN2	1.01e-04	186	47	5	IPR017970
Domain	Homeodomain-like	RHOXF2B MNX1 RHOXF2 PDX1 POGZ EN2	1.75e-04	332	47	6	IPR009057
Domain	Homeobox	RHOXF2B MNX1 RHOXF2 PDX1 EN2	2.95e-04	234	47	5	PF00046
Domain	HOMEOBOX_1	RHOXF2B MNX1 RHOXF2 PDX1 EN2	3.07e-04	236	47	5	PS00027
Domain	HOX	RHOXF2B MNX1 RHOXF2 PDX1 EN2	3.13e-04	237	47	5	SM00389
Domain	Homeobox_dom	RHOXF2B MNX1 RHOXF2 PDX1 EN2	3.26e-04	239	47	5	IPR001356
Domain	HOMEOBOX_2	RHOXF2B MNX1 RHOXF2 PDX1 EN2	3.26e-04	239	47	5	PS50071
Domain	Collagen	COL11A2 OTOL1 MARCO	1.28e-03	85	47	3	PF01391
Domain	Collagen	COL11A2 OTOL1 MARCO	1.28e-03	85	47	3	IPR008160
Domain	Homeobox_metazoa	MNX1 PDX1 EN2	1.51e-03	90	47	3	IPR020479
Domain	TGFb_propeptide	INHBA GDF11	2.25e-03	28	47	2	PF00688
Domain	TGF-b_N	INHBA GDF11	2.25e-03	28	47	2	IPR001111
Domain	ATPase_AAA_CS	AFG3L2 PSMC1	2.41e-03	29	47	2	IPR003960
Domain	TGF-beta-rel	INHBA GDF11	2.93e-03	32	47	2	IPR015615
Domain	TGFb_CS	INHBA GDF11	2.93e-03	32	47	2	IPR017948
Domain	AAA	AFG3L2 PSMC1	3.30e-03	34	47	2	PS00674
Domain	TGFB	INHBA GDF11	3.90e-03	37	47	2	SM00204
Domain	TGF_BETA_2	INHBA GDF11	3.90e-03	37	47	2	PS51362
Domain	TGF_beta	INHBA GDF11	3.90e-03	37	47	2	PF00019
Domain	TGF-b_C	INHBA GDF11	3.90e-03	37	47	2	IPR001839
Domain	TGF_BETA_1	INHBA GDF11	3.90e-03	37	47	2	PS00250
Domain	TF_fork_head_CS_2	FOXL2 FOXA1	5.98e-03	46	47	2	IPR030456
Domain	TF_fork_head_CS_1	FOXL2 FOXA1	6.23e-03	47	47	2	IPR018122
Domain	FORK_HEAD_3	FOXL2 FOXA1	6.76e-03	49	47	2	PS50039
Domain	FH	FOXL2 FOXA1	6.76e-03	49	47	2	SM00339
Domain	FORK_HEAD_1	FOXL2 FOXA1	6.76e-03	49	47	2	PS00657
Domain	FORK_HEAD_2	FOXL2 FOXA1	6.76e-03	49	47	2	PS00658
Domain	Forkhead	FOXL2 FOXA1	6.76e-03	49	47	2	PF00250
Domain	Fork_head_dom	FOXL2 FOXA1	6.76e-03	49	47	2	IPR001766
Domain	AAA	AFG3L2 PSMC1	7.59e-03	52	47	2	PF00004
Domain	ATPase_AAA_core	AFG3L2 PSMC1	8.16e-03	54	47	2	IPR003959
Domain	-	INHBA GDF11	1.24e-02	67	47	2	2.10.90.10
Domain	Cystine-knot_cytokine	INHBA GDF11	1.24e-02	67	47	2	IPR029034
Domain	ZINC_FINGER_C2H2_2	ZBTB22 PRDM13 POGZ YY1 ZNF687 ZNF503	1.26e-02	775	47	6	PS50157
Domain	ZINC_FINGER_C2H2_1	ZBTB22 PRDM13 POGZ YY1 ZNF687 ZNF503	1.28e-02	777	47	6	PS00028
Domain	Znf_C2H2-like	ZBTB22 PRDM13 POGZ YY1 ZNF687 ZNF503	1.43e-02	796	47	6	IPR015880
Domain	Znf_C2H2	ZBTB22 PRDM13 POGZ YY1 ZNF687 ZNF503	1.50e-02	805	47	6	IPR007087
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	SOX4 MSC FOXL2 MNX1 RHOXF2 ZBTB22 PDX1 FOXA1 EN2 YY1	3.84e-09	544	49	10	28473536
Pubmed	Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.	RHOXF2B RHOXF2 DNAJB6	3.13e-07	10	49	3	21972064
Pubmed	Human transcription factor protein interaction networks.	SOX4 PRR12 IRS4 MNX1 PSMC1 MLLT6 POGZ FOXA1 CHMP4B YY1 ZNF687 ZNF503	4.97e-07	1429	49	12	35140242
Pubmed	RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors.	MNX1 PDX1 FOXA1	5.73e-07	12	49	3	22232429
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	IRS4 SERBP1 H4C1 POGZ YY1 ZNF687 HNRNPU	6.71e-07	357	49	7	37059091
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	IRS4 SERBP1 H4C1 AFG3L2 DNAJB6 PSMC1 YY1 HNRNPU	1.16e-06	565	49	8	33567341
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2B RHOXF2	1.94e-06	2	49	2	12087094
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2B RHOXF2	1.94e-06	2	49	2	16496311
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2B RHOXF2	1.94e-06	2	49	2	16465597
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2B RHOXF2	1.94e-06	2	49	2	16414020
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 H4C1 PSMC1 MLLT6 POGZ CHMP4B YY1 ZNF687 HNRNPU ZNF503	2.64e-06	1103	49	10	34189442
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX4 MSC FOXL2 MNX1 RHOXF2 PDX1 FOXA1 EN2 YY1	4.36e-06	908	49	9	19274049
Pubmed	The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.	RHOXF2B RHOXF2	5.83e-06	3	49	2	18562707
Pubmed	Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators.	INHBA GDF11	5.83e-06	3	49	2	18927237
Pubmed	Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer.	PDX1 EN2	5.83e-06	3	49	2	35169223
Pubmed	The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c.	RHOXF2B RHOXF2	5.83e-06	3	49	2	18077458
Pubmed	A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription.	FOXL2 INHBA	5.83e-06	3	49	2	19324968
Pubmed	FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.	FOXL2 FOXA1	5.83e-06	3	49	2	35920317
Pubmed	Directed differentiation of telencephalic precursors from embryonic stem cells.	MNX1 EN2 ZNF503	5.91e-06	25	49	3	15696161
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SOX4 RHOXF2B MNX1 RHOXF2 ZBTB22 POGZ FOXA1 ZNF687	6.18e-06	709	49	8	22988430
Pubmed	The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.	IRS4 SERBP1 AMOTL1 AFG3L2 DNAJB6 CHMP4B	9.66e-06	350	49	6	26549023
Pubmed	Targeted recruitment of a histone H4-specific methyltransferase by the transcription factor YY1.	H4C1 YY1	1.16e-05	4	49	2	12704081
Pubmed	Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin.	INHBA GDF11	1.16e-05	4	49	2	18535106
Pubmed	Rhox: a new homeobox gene cluster.	RHOXF2B RHOXF2	1.16e-05	4	49	2	15707895
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	SERBP1 H4C1 AFG3L2 DNAJB6 DOCK10 PSMC1 HNRNPU	1.26e-05	558	49	7	27591049
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	IRS4 GAREM2 CLASP2 WIPF2	1.39e-05	103	49	4	21706016
Pubmed	Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder.	PDX1 FOXA1	1.94e-05	5	49	2	29023691
Pubmed	Developmentally regulated Shh expression is robust to TAD perturbations.	MNX1 EN2	1.94e-05	5	49	2	31511252
Pubmed	Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.	RHOXF2B RHOXF2	1.94e-05	5	49	2	14648851
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 H4C1 AFG3L2 DNAJB6 FMN2 POGZ FOXA1 YY1 ZNF687	2.26e-05	1116	49	9	31753913
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	IRS4 SERBP1 FMN2 YY1 HNRNPU	2.47e-05	245	49	5	35652658
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	IRS4 H4C1 RRP9 PSMC1 CLASP2 ZNF687 HNRNPU	2.59e-05	624	49	7	33729478
Pubmed	The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade.	MNX1 PDX1	2.91e-05	6	49	2	12781686
Pubmed	Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins.	SERBP1 DNAJB6 HNRNPU	3.58e-05	45	49	3	24654937
Pubmed	ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.	SERBP1 PSMC1 HNRNPU	3.82e-05	46	49	3	20890123
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	SERBP1 H4C1 AFG3L2 PSMC1 HNRNPU	3.85e-05	269	49	5	30442662
Pubmed	A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice.	MNX1 EN2	4.07e-05	7	49	2	10945466
Pubmed	Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man.	MNX1 PDX1	4.07e-05	7	49	2	24411943
Pubmed	An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs.	MNX1 PDX1	4.07e-05	7	49	2	17478445
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	CDV3 IRS4 SERBP1 H4C1 AFG3L2 CHMP4B PDCD4 HNRNPU	4.46e-05	934	49	8	33916271
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	IRS4 SERBP1 H4C1 RRP9 HNRNPU	4.74e-05	281	49	5	26725010
Pubmed	RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcription.	SERBP1 PSMC1 HNRNPU	4.92e-05	50	49	3	30413534
Pubmed	TFCP2 Is Required for YAP-Dependent Transcription to Stimulate Liver Malignancy.	MSC FOXA1	5.42e-05	8	49	2	29091762
Pubmed	Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells.	GJD2 PDX1	5.42e-05	8	49	2	22729650
Pubmed	Transcriptional dynamics of endodermal organ formation.	MNX1 PDX1	5.42e-05	8	49	2	19097184
Pubmed	A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.	INHBA GDF11	5.42e-05	8	49	2	31187730
Pubmed	HNF-3 beta as a regulator of floor plate development.	FOXA1 EN2	5.42e-05	8	49	2	8287471
Pubmed	Dorsal pancreas agenesis in N-cadherin- deficient mice.	MNX1 PDX1	5.42e-05	8	49	2	11784004
Pubmed	LINKIN, a new transmembrane protein necessary for cell adhesion.	IRS4 SERBP1 H4C1 DNAJB6 YY1 HNRNPU	5.67e-05	480	49	6	25437307
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SERBP1 H4C1 RRP9 AMOTL1 AFG3L2 DNAJB6 PSMC1 PDCD4 HNRNPU	5.70e-05	1257	49	9	36526897
Pubmed	Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.	CDV3 IRS4 SERBP1	6.20e-05	54	49	3	25631074
Pubmed	The shieldin complex mediates 53BP1-dependent DNA repair.	PRR12 AFG3L2 POGZ	6.91e-05	56	49	3	30022168
Pubmed	A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells.	MNX1 PDX1	6.96e-05	9	49	2	26440894
Pubmed	The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.	FOXL2 INHBA	6.96e-05	9	49	2	14736745
Pubmed	Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.	PDX1 FOXA1	6.96e-05	9	49	2	20534694
Pubmed	Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.	SERBP1 HNRNPU	6.96e-05	9	49	2	19858291
Pubmed	RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.	IRS4 SERBP1 CLASP2 HNRNPU	7.05e-05	156	49	4	26170170
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 FOXL2 H4C1 RRP9 AFG3L2 POGZ YY1 ZNF687 HNRNPU	7.13e-05	1294	49	9	30804502
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SERBP1 RRP9 CLASP2 PDCD4	8.36e-05	163	49	4	22113938
Pubmed	The onecut transcription factor HNF6 is required for normal development of the biliary tract.	PDX1 FOXA1	8.69e-05	10	49	2	11934848
Pubmed	Early mouse endoderm is patterned by soluble factors from adjacent germ layers.	PDX1 FOXA1	8.69e-05	10	49	2	10725233
Pubmed	Analysis of pancreatic endocrine development in GDF11-deficient mice.	PDX1 GDF11	8.69e-05	10	49	2	16964608
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	IRS4 SERBP1 H4C1 CLASP2 HNRNPU	9.82e-05	328	49	5	23398456
Pubmed	Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.	GJD2 MNX1 PDX1	9.83e-05	63	49	3	25053427
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	CDV3 SERBP1 DNAJB6 CHMP4B YY1	9.96e-05	329	49	5	34316702
Pubmed	Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice.	MNX1 PDX1	1.06e-04	11	49	2	16026781
Pubmed	SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.	IRS4 SOCS7	1.06e-04	11	49	2	12052866
Pubmed	Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate.	INHBA GDF11	1.06e-04	11	49	2	21852401
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	IRS4 AFG3L2 PSMC1 CLASP2 WIPF2 PDCD4	1.16e-04	547	49	6	37267103
Pubmed	A new in vivo cross-linking mass spectrometry platform to define protein-protein interactions in living cells.	H4C1 PSMC1 HNRNPU	1.18e-04	67	49	3	25253489
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	IRS4 SERBP1 H4C1 CLASP2 PDCD4 HNRNPU	1.21e-04	551	49	6	34728620
Pubmed	A major X-linked locus affects kidney function in mice.	RHOXF2B RHOXF2	1.27e-04	12	49	2	23011808
Pubmed	Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.	RHOXF2B RHOXF2	1.27e-04	12	49	2	29500366
Pubmed	Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9.	MNX1 PDX1	1.27e-04	12	49	2	10471501
Pubmed	VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.	MNX1 GDF11	1.27e-04	12	49	2	18519639
Pubmed	Lack of TCF2/vHNF1 in mice leads to pancreas agenesis.	MNX1 PDX1	1.27e-04	12	49	2	15668393
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	CDV3 SERBP1 H4C1 AFG3L2 CLASP2 CHMP4B	1.29e-04	558	49	6	35063084
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	CDV3 SERBP1 H4C1 AFG3L2 PSMC1 CLASP2 YY1 PDCD4 HNRNPU	1.41e-04	1415	49	9	28515276
Pubmed	Revealing A-Raf functions through its interactome.	IRS4 H4C1 DNAJB6 HNRNPU	1.42e-04	187	49	4	29777862
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IRS4 SERBP1 H4C1 RRP9 PSMC1 CLASP2 POGZ CHMP4B HNRNPU	1.48e-04	1425	49	9	30948266
Pubmed	Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.	PDX1 FOXA1	1.50e-04	13	49	2	23471965
Pubmed	Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.	IRS4 H4C1	1.50e-04	13	49	2	29285303
Pubmed	Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.	MNX1 PDX1	1.50e-04	13	49	2	18199433
Pubmed	Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice.	MNX1 PDX1	1.50e-04	13	49	2	10471502
Pubmed	Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification.	SOX4 GDF11	1.50e-04	13	49	2	31155355
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	CDV3 SERBP1 CHMP4B WIPF2 HNRNPU	1.52e-04	360	49	5	33111431
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	IRS4 H4C1 POGZ YY1 ZNF687 HNRNPU	1.64e-04	583	49	6	29844126
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RRP9 DNAJB6 CLASP2 YY1 PDCD4	1.72e-04	370	49	5	22922362
Pubmed	Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas.	MNX1 PDX1	1.75e-04	14	49	2	14736744
Pubmed	The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation.	MNX1 PDX1	1.75e-04	14	49	2	14729487
Pubmed	Depletion of definitive gut endoderm in Sox17-null mutant mice.	PDX1 FOXA1	1.75e-04	14	49	2	11973269
Pubmed	Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells.	INHBA PDX1	1.75e-04	14	49	2	15277382
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	CDV3 IRS4 SERBP1 H4C1 AMOTL1 PSMC1 CLASP2 HNRNPU	1.87e-04	1149	49	8	35446349
Pubmed	HNF-3 beta is essential for node and notochord formation in mouse development.	FOXA1 EN2	2.02e-04	15	49	2	8069909
Pubmed	PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.	H4C1 YY1	2.02e-04	15	49	2	15674325
Pubmed	Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development.	MNX1 PDX1	2.02e-04	15	49	2	11784060
Pubmed	Defining the membrane proteome of NK cells.	SERBP1 SPN H4C1 DNAJB6 DOCK10 PSMC1 CLASP2 HNRNPU	2.10e-04	1168	49	8	19946888
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	IRS4 AFG3L2 DOCK10 PSMC1	2.13e-04	208	49	4	33230847
Pubmed	A cohesin-RAD21 interactome.	H4C1 PSMC1 CLASP2 HNRNPU	2.13e-04	208	49	4	22145905
Pubmed	Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.	PDX1 FOXA1	2.30e-04	16	49	2	19141476
Interaction	SNU13 interactions	CDV3 SERBP1 H4C1 RRP9 FOXA1 CHMP4B YY1 HNRNPU	3.96e-07	285	49	8	int:SNU13
Interaction	TBL3 interactions	H4C1 RRP9 DNAJB6 FOXA1 CHMP4B HNRNPU	4.45e-06	178	49	6	int:TBL3
Interaction	NIP7 interactions	SERBP1 H4C1 DNAJB6 FOXA1 CHMP4B HNRNPU	5.22e-06	183	49	6	int:NIP7
Interaction	NFIA interactions	PRR12 MNX1 H4C1 FOXA1 YY1 HNRNPU	6.10e-06	188	49	6	int:NFIA
Interaction	UTP15 interactions	SERBP1 H4C1 RRP9 DNAJB6 CHMP4B	6.96e-06	110	49	5	int:UTP15
Interaction	TFCP2 interactions	PRMT6 IRS4 MSC H4C1 AMOTL1 FOXA1 YY1 HNRNPU	9.33e-06	436	49	8	int:TFCP2
Interaction	NFIC interactions	PRR12 MNX1 H4C1 POGZ FOXA1 YY1	1.15e-05	210	49	6	int:NFIC
Interaction	H2BC12 interactions	SERBP1 H4C1 PRDM13 CLASP2 CHMP4B YY1 PDCD4	1.20e-05	322	49	7	int:H2BC12
Interaction	PAX4 interactions	PDX1 PSMC1 HNRNPU	1.27e-05	19	49	3	int:PAX4
Interaction	RRP9 interactions	SERBP1 H4C1 RRP9 FOXA1 CHMP4B	1.40e-05	127	49	5	int:RRP9
Interaction	DAXX interactions	SERBP1 SPN H4C1 MLLT6 POGZ CHMP4B PDCD4	2.18e-05	353	49	7	int:DAXX
Interaction	PAX6 interactions	PRR12 MNX1 H4C1 MLLT6 POGZ YY1 ZNF503	2.74e-05	366	49	7	int:PAX6
Interaction	UTP18 interactions	H4C1 RRP9 DNAJB6 FOXA1 HNRNPU	3.33e-05	152	49	5	int:UTP18
Interaction	H2BC4 interactions	H4C1 AFG3L2 CLASP2 CHMP4B YY1 PDCD4	3.74e-05	259	49	6	int:H2BC4
Interaction	RPL15 interactions	ZSWIM8 SERBP1 H4C1 DNAJB6 CLASP2 CHMP4B ZNF687 HNRNPU	3.79e-05	530	49	8	int:RPL15
Interaction	VARS1 interactions	SERBP1 FOXL2 H4C1 MLLT6 FOXA1 HNRNPU	3.82e-05	260	49	6	int:VARS1
Interaction	WDR3 interactions	H4C1 RRP9 DNAJB6 CHMP4B HNRNPU	4.26e-05	160	49	5	int:WDR3
Interaction	C19orf53 interactions	H4C1 FOXA1 HNRNPU	4.72e-05	29	49	3	int:C19orf53
Interaction	POP1 interactions	SERBP1 FOXL2 H4C1 FOXA1 YY1 HNRNPU	5.44e-05	277	49	6	int:POP1
Interaction	THOC6 interactions	SERBP1 H4C1 RRP9 HNRNPU	5.92e-05	87	49	4	int:THOC6
Interaction	TLX1 interactions	PRR12 MNX1 POGZ CHMP4B ZNF503	6.53e-05	175	49	5	int:TLX1
Interaction	CBX1 interactions	PRR12 H4C1 POGZ CHMP4B YY1 HNRNPU	6.75e-05	288	49	6	int:CBX1
Interaction	KLF16 interactions	IRS4 SERBP1 H4C1 PSMC1 POGZ YY1 ZNF503	7.06e-05	425	49	7	int:KLF16
Interaction	H2BC1 interactions	SERBP1 H4C1 CHMP4B PDCD4 HNRNPU	7.07e-05	178	49	5	int:H2BC1
Interaction	PURA interactions	SERBP1 H4C1 RRP9 PSMC1 PDCD4 SYNGAP1	7.14e-05	291	49	6	int:PURA
Interaction	TLX3 interactions	PRR12 MNX1 H4C1 POGZ ZNF503 SYNGAP1	7.14e-05	291	49	6	int:TLX3
Interaction	FBXL6 interactions	IRS4 H4C1 AFG3L2 PSMC1 CLASP2 WIPF2 PDCD4 HNRNPU	7.41e-05	583	49	8	int:FBXL6
Interaction	SPRTN interactions	IRS4 SERBP1 H4C1 AFG3L2 DNAJB6 PSMC1 YY1 HNRNPU	8.64e-05	596	49	8	int:SPRTN
Interaction	H2BC14 interactions	SERBP1 H4C1 YY1 PDCD4	1.02e-04	100	49	4	int:H2BC14
Interaction	ID2 interactions	PRMT6 MSC CLASP2 YY1	1.23e-04	105	49	4	int:ID2
Interaction	CKAP5 interactions	SERBP1 H4C1 DNAJB6 CLASP2 CHMP4B HNRNPU	1.25e-04	322	49	6	int:CKAP5
Interaction	GULP1 interactions	SERBP1 MLLT6 SYNGAP1	1.25e-04	40	49	3	int:GULP1
Interaction	FEV interactions	PRR12 MNX1 POGZ YY1 ZNF503	1.31e-04	203	49	5	int:FEV
Interaction	DAB1 interactions	RHOXF2 CLASP2 POGZ SOCS7	1.32e-04	107	49	4	int:DAB1
Interaction	BANF1 interactions	SOX4 FOXL2 H4C1 FOXA1 CHMP4B	1.34e-04	204	49	5	int:BANF1
Interaction	WDR36 interactions	H4C1 RRP9 DNAJB6 CHMP4B HNRNPU	1.47e-04	208	49	5	int:WDR36
Interaction	DDRGK1 interactions	IRS4 SERBP1 H4C1 RRP9 AFG3L2 DNAJB6 PSMC1 CLASP2 FOXA1 CHMP4B HNRNPU	1.63e-04	1249	49	11	int:DDRGK1
Interaction	UBE2I interactions	SOX4 FOXL2 H4C1 RHOXF2 CHMP4B YY1 MARCO HNRNPU	1.64e-04	654	49	8	int:UBE2I
Interaction	ELF4 interactions	H4C1 POGZ YY1 ZNF687	1.75e-04	115	49	4	int:ELF4
Interaction	C7orf50 interactions	SERBP1 H4C1 RRP9 FOXA1 YY1	1.83e-04	218	49	5	int:C7orf50
Interaction	IQSEC1 interactions	PRMT6 DNAJB6 MLLT6 SYNGAP1	1.93e-04	118	49	4	int:IQSEC1
Interaction	FIP1L1 interactions	PRMT6 FOXL2 H4C1 FOXA1 YY1	2.12e-04	225	49	5	int:FIP1L1
Interaction	CENPV interactions	H4C1 DNAJB6 CHMP4B HNRNPU	2.13e-04	121	49	4	int:CENPV
Interaction	C12orf43 interactions	H4C1 FOXA1 HNRNPU	2.16e-04	48	49	3	int:C12orf43
Interaction	NFIX interactions	PRR12 H4C1 POGZ FOXA1 YY1	2.21e-04	227	49	5	int:NFIX
Interaction	RFC4 interactions	SERBP1 H4C1 FOXA1 CHMP4B HNRNPU	2.21e-04	227	49	5	int:RFC4
Interaction	H2BC21 interactions	PRMT6 PRR12 SERBP1 H4C1 POGZ PDCD4 ZNF687 HNRNPU	2.50e-04	696	49	8	int:H2BC21
Interaction	UBTF interactions	H4C1 DNAJB6 FOXA1 CHMP4B HNRNPU	2.54e-04	234	49	5	int:UBTF
Interaction	GALE interactions	SERBP1 DNAJB6 HNRNPU	2.90e-04	53	49	3	int:GALE
Interaction	MAP1LC3A interactions	IRS4 SERBP1 IRGQ PDCD4 HNRNPU	2.91e-04	241	49	5	int:MAP1LC3A
Interaction	MYB interactions	H4C1 MLLT6 POGZ YY1	3.05e-04	133	49	4	int:MYB
Interaction	LOC102724334 interactions	H4C1 MLLT6 YY1 PDCD4	3.14e-04	134	49	4	int:LOC102724334
Interaction	NF2 interactions	SOX4 IRS4 SERBP1 AMOTL1 AFG3L2 CHMP4B	3.18e-04	383	49	6	int:NF2
Interaction	RAD21 interactions	H4C1 AFG3L2 PSMC1 CLASP2 YY1 HNRNPU	3.22e-04	384	49	6	int:RAD21
Interaction	VTA1 interactions	SERBP1 PSMC1 FOXA1 CHMP4B	3.42e-04	137	49	4	int:VTA1
Interaction	CREB1 interactions	H4C1 PDX1 POGZ FOXA1 YY1	3.71e-04	254	49	5	int:CREB1
Interaction	CRX interactions	PRR12 MNX1 RHOXF2 MLLT6 POGZ	3.71e-04	254	49	5	int:CRX
Interaction	ACSL4 interactions	SERBP1 FOXL2 CHMP4B HNRNPU	3.71e-04	140	49	4	int:ACSL4
Interaction	PAN2 interactions	IRS4 SERBP1 FOXL2 H4C1 CLASP2 HNRNPU	3.85e-04	397	49	6	int:PAN2
Interaction	HDAC4 interactions	PRR12 ZSWIM8 DNAJB6 FMN2 CLASP2 YY1 PDCD4 HNRNPU	3.92e-04	744	49	8	int:HDAC4
Interaction	NOP56 interactions	SERBP1 H4C1 RRP9 MLLT6 CHMP4B YY1 HNRNPU	4.28e-04	570	49	7	int:NOP56
Interaction	SLX4 interactions	IRS4 SERBP1 H4C1 POGZ YY1 ZNF687 HNRNPU	4.37e-04	572	49	7	int:SLX4
Interaction	MAGEL2 interactions	IRS4 SERBP1 HNRNPU	4.40e-04	61	49	3	int:MAGEL2
Interaction	EPS8L2 interactions	CDV3 SERBP1 DNAJB6	4.40e-04	61	49	3	int:EPS8L2
Interaction	SPAG9 interactions	SOX4 SERBP1 SPN PSMC1 HNRNPU	4.74e-04	268	49	5	int:SPAG9
Interaction	MDC1 interactions	SERBP1 H4C1 AFG3L2 POGZ YY1 HNRNPU	4.80e-04	414	49	6	int:MDC1
Interaction	ATF7 interactions	H4C1 MLLT6 YY1	4.84e-04	63	49	3	int:ATF7
Interaction	SRSF10 interactions	H4C1 PSMC1 FOXA1 CHMP4B ZNF687	4.98e-04	271	49	5	int:SRSF10
Interaction	NAA40 interactions	CDV3 IRS4 SERBP1 H4C1 AFG3L2 FOXA1 CHMP4B PDCD4 HNRNPU	5.12e-04	978	49	9	int:NAA40
Interaction	RPL5 interactions	SERBP1 H4C1 RRP9 FOXA1 CHMP4B PDCD4 HNRNPU	6.16e-04	606	49	7	int:RPL5
Interaction	UBA52 interactions	SERBP1 H4C1 PSMC1 YY1 PDCD4 HNRNPU	6.38e-04	437	49	6	int:UBA52
Interaction	TMEM41B interactions	IRS4 H4C1 AFG3L2 HNRNPU	6.43e-04	162	49	4	int:TMEM41B
Interaction	TMEM33 interactions	SERBP1 H4C1 FOXA1 CHMP4B	6.58e-04	163	49	4	int:TMEM33
Interaction	RBM3 interactions	PRMT6 CDV3 H4C1 FOXA1	6.58e-04	163	49	4	int:RBM3
Interaction	DHX33 interactions	H4C1 FOXA1 HNRNPU	6.59e-04	70	49	3	int:DHX33
Interaction	GRB2 interactions	IRS4 SERBP1 GAREM2 CLASP2 FOXA1 WIPF2 SOCS7 HNRNPU	6.66e-04	806	49	8	int:GRB2
Interaction	ADSS1 interactions	AFG3L2 YY1	6.80e-04	16	49	2	int:ADSS1
Interaction	GTPBP4 interactions	SOX4 SERBP1 H4C1 DNAJB6 CHMP4B HNRNPU	6.85e-04	443	49	6	int:GTPBP4
Interaction	CEBPA interactions	PRR12 H4C1 PSMC1 MLLT6 POGZ CHMP4B YY1 ZNF687 HNRNPU ZNF503	7.02e-04	1245	49	10	int:CEBPA
Interaction	HSPA7 interactions	SERBP1 H4C1 CHMP4B	7.45e-04	73	49	3	int:HSPA7
Interaction	NBEAL1 interactions	CHMP4B HNRNPU	7.69e-04	17	49	2	int:NBEAL1
Interaction	NDN interactions	IRS4 SERBP1 H4C1 POGZ CHMP4B HNRNPU	7.70e-04	453	49	6	int:NDN
Cytoband	7q36	MNX1 EN2	3.85e-04	27	49	2	7q36
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	MNX1 DNAJB6 EN2	6.68e-04	159	49	3	chr7q36
Cytoband	10q22.2	ZSWIM8 ZNF503	8.91e-04	41	49	2	10q22.2
Cytoband	Xq24	RHOXF2B RHOXF2	2.16e-03	64	49	2	Xq24
Cytoband	6p21.3	COL11A2 ZBTB22 SYNGAP1	2.44e-03	250	49	3	6p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chrXq24	RHOXF2B RHOXF2	3.43e-03	81	49	2	chrXq24
Cytoband	1q21.3	POGZ ZNF687	7.00e-03	117	49	2	1q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3q22	CDV3 FOXL2	9.22e-03	135	49	2	chr3q22
GeneFamily	Forkhead boxes	FOXL2 FOXA1	2.78e-03	43	33	2	508
GeneFamily	HOXL subclass homeoboxes	MNX1 PDX1	4.05e-03	52	33	2	518
GeneFamily	AAA ATPases	AFG3L2 PSMC1	4.20e-03	53	33	2	413
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-.Sp.TCRbko, TCRd+ Vg2- CD44-, Spleen, avg-3	SOX4 PRR12 SPN RUNDC3B MLLT6 GDF11 PDCD4	2.84e-05	405	47	7	GSM605796_500
ToppCell	Substantia_nigra\|World / BrainAtlas - Mouse McCarroll V32	IRS4 FOXA1 EN2 MARCO ZNF503	1.74e-07	115	49	5	18174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 DOCK10 CLASP2 PDCD4 HNRNPU	2.26e-06	193	49	5	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 DOCK10 CLASP2 PDCD4 HNRNPU	2.26e-06	193	49	5	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 DOCK10 CLASP2 PDCD4 HNRNPU	2.26e-06	193	49	5	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 DOCK10 CLASP2 PDCD4 HNRNPU	2.26e-06	193	49	5	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	SOX4 NPPC CDV3 DNAJB6 GDF11	2.49e-06	197	49	5	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 MNX1 FAM181A SOCS7	2.88e-05	160	49	4	af84da18c85037f49f55e8958f00f12140226982
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 MNX1 FAM181A SOCS7	2.88e-05	160	49	4	f7ca98beaa24f9674d503588eb15d341c4135d77
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 MNX1 FAM181A SOCS7	2.88e-05	160	49	4	a76ad44b5f25f59d6b9333fb45f8bb96196a3090
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDV3 FOXA1 CHMP4B HNRNPU	4.37e-05	178	49	4	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	SPN INHBA AMOTL1 MARCO	5.63e-05	190	49	4	2592765016f291565697265800a232b2edef3792
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX4 SERBP1 AMOTL1 HNRNPU	5.63e-05	190	49	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RUNDC3B INHBA OTOL1 ZNF503	5.63e-05	190	49	4	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	10x3'2.3\|World / cell types per 3 fetal stages;per 3',per 5'	SOX4 NPPC CDV3 DNAJB6	6.10e-05	194	49	4	fc7ed8350ffe1475b8934dfbb107b51991876b0b
ToppCell	droplet-Limb_Muscle-MUSCLE-1m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 CDV3 COL11A2 PDCD4	6.22e-05	195	49	4	fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	SPN RUNDC3B INHBA MARCO	6.22e-05	195	49	4	dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 NPPC MSC RRP9	6.35e-05	196	49	4	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 DNAJB6 CLASP2 HNRNPU	6.47e-05	197	49	4	d9a5b6171867de21d4ef12aa5a802fb4de9e0c00
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPN INHBA AMOTL1 MARCO	6.47e-05	197	49	4	d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCell	Severe_COVID-19-Myeloid-TRAM2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SPN INHBA AMOTL1 MARCO	6.47e-05	197	49	4	8a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 DNAJB6 CLASP2 HNRNPU	6.47e-05	197	49	4	b4554353c56e220bae31ee3c8aa222674dd0b18c
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPN INHBA AMOTL1 MARCO	6.47e-05	197	49	4	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPN INHBA AMOTL1 MARCO	6.47e-05	197	49	4	9262785807faeb32417fad7ef202405053e453e2
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPN INHBA AMOTL1 MARCO	6.47e-05	197	49	4	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	mLN-T_cell-Th17\|mLN / Region, Cell class and subclass	MSC DNAJB6 MLLT6 IRGQ	6.60e-05	198	49	4	04905f62941b193864704a10ad692faf777fa51d
ToppCell	mLN-(1)_T_cell-(13)_Th17\|mLN / shred on region, Cell_type, and subtype	MSC DNAJB6 MLLT6 IRGQ	6.60e-05	198	49	4	c575e9aeee4e034e8c4d171fe754403652343731
ToppCell	mLN-T_cell-Th17\|T_cell / Region, Cell class and subclass	MSC DNAJB6 MLLT6 IRGQ	6.60e-05	198	49	4	efdc9515dd9fb20ef9c8ddc106d88cbdde7d6ea2
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RHOXF2 PRDM13 MLLT6 PDCD4	6.73e-05	199	49	4	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	Parenchyma_Control_(B.)\|World / Sample group, Lineage and Cell type	CDV3 SPN INHBA MARCO	6.86e-05	200	49	4	220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	SOX4 RUNDC3B DNAJB6 ZNF503	6.86e-05	200	49	4	c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CDV3 COL11A2 PDCD4	2.41e-04	110	49	3	ee45592e936d32881c0f3429c21360670e5b3ce3
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CDV3 COL11A2 PDCD4	2.41e-04	110	49	3	b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	COL11A2 DOCK10 MLLT6	3.60e-04	126	49	3	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMN2 GDF11 ZNF687	3.77e-04	128	49	3	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Neuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	SOX4 FOXA1 EN2	3.85e-04	129	49	3	64768adf23123b92280fb30eb85147cbee084ae0
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SPN INHBA FOXA1	4.99e-04	141	49	3	399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SOX4 H4C1 DNAJB6	5.31e-04	144	49	3	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SOX4 MSC MARCO	5.75e-04	148	49	3	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJD2 INHBA PDX1	6.46e-04	154	49	3	46155f36d3983f637b55d7525b675c8828f6ab2e
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJD2 INHBA PDX1	6.46e-04	154	49	3	71ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCell	droplet-Liver-Npc-21m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN ZBTB22 WIPF2	6.83e-04	157	49	3	264b22d0ffc43049161843bb55d2eccbf5fca575
ToppCell	facs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPN RUNDC3B PDCD4	6.83e-04	157	49	3	34eb1cbdb023d3e23b2e1695c9c327c21ef1c870
ToppCell	droplet-Liver-Npc-21m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN ZBTB22 WIPF2	6.83e-04	157	49	3	67945d37027be62c880d3072afa7ca7e97c76c20
ToppCell	facs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPN RUNDC3B PDCD4	6.83e-04	157	49	3	fc0c222124f59c94d60335f849554eaa4062f8c7
ToppCell	facs-Lung-24m-Hematologic-Lymphocytic_NK_ILC\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPN RUNDC3B PDCD4	6.83e-04	157	49	3	40b08ace1d9ea7951886f5fed76ac57e9175436b
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	INHBA FAM181A FMN2	7.08e-04	159	49	3	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPN INHBA MARCO	7.21e-04	160	49	3	48c0d0486873733f0d7c8dca3a657879d35cfd43
ToppCell	Control-CD8+_T\|World / Disease group and Cell class	MSC INHBA MARCO	7.21e-04	160	49	3	f5151f5cf1a4a4a997496e03e48293e4c751d077
ToppCell	Control\|World / Disease group and Cell class	MSC INHBA MARCO	7.34e-04	161	49	3	e3e72cda7cc70f06d669f26ccf06d51346d7136f
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXA1 EN2 MARCO	7.34e-04	161	49	3	b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPN DOCK10 PDCD4	7.88e-04	165	49	3	5f606959a060b1ae241217889560c6761ac73bbb
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPPC FOXL2 RHOXF2	8.02e-04	166	49	3	d1c61270c7b39bb365020eeafe298a8f88aa887e
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSC RUNDC3B H4C1	8.45e-04	169	49	3	822e5b6c1e55e196e6d2a38bf183fd220c45703e
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL11A2 MNX1 FOXA1	8.45e-04	169	49	3	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	droplet-Liver-Npc\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN DOCK10 MARCO	8.59e-04	170	49	3	09c836840216905d545a25a4fc1bbd0699576c77
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 COL11A2 FAM181A	8.74e-04	171	49	3	d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDX1 FAM181A FOXA1	8.74e-04	171	49	3	a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 COL11A2 FAM181A	8.74e-04	171	49	3	fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 COL11A2 FAM181A	8.74e-04	171	49	3	d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 COL11A2 FAM181A	8.74e-04	171	49	3	4347e6f62c04ea43299893ad4b79719049009a56
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|bone_marrow / Manually curated celltypes from each tissue	SOX4 SPN IRGQ	8.89e-04	172	49	3	a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCell	facs-Lung-nan-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN DOCK10 PDCD4	8.89e-04	172	49	3	7af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCell	Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SPN INHBA MARCO	9.04e-04	173	49	3	a112da5b0ab6e1f13d1a7dfa72c67c9a95fa9243
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPN INHBA MARCO	9.34e-04	175	49	3	d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RUNDC3B DOCK10 PDCD4	9.34e-04	175	49	3	06eace2e681980456299167b48bd49bcfea5e940
ToppCell	Bronchial_Biopsy-Immune-Luminal_Macrophages\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SPN INHBA MARCO	9.34e-04	175	49	3	1cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDX1 FMN2 FOXA1	9.50e-04	176	49	3	fb718a6b07aa5d56600263280afa530bcb63db42
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPPC COL11A2 INHBA	9.50e-04	176	49	3	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPPC DOCK10 EN2	9.66e-04	177	49	3	6f3b254e56e722cc23495b49e99a4abce0243cb3
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSC H4C1 INHBA	9.81e-04	178	49	3	9fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPPC COL11A2 FOXA1	9.97e-04	179	49	3	c7d7a66fca6a41de0af3cc2b75a29a54456842cd
ToppCell	T_cells-GZMK+_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	MSC PSMC1 PDCD4	9.97e-04	179	49	3	798f208014f2229c597934775646ddbbacf94b69
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	SPN INHBA MARCO	1.03e-03	181	49	3	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SPN INHBA MARCO	1.05e-03	182	49	3	a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	SPN INHBA MARCO	1.08e-03	184	49	3	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INHBA DOCK10 MARCO	1.08e-03	184	49	3	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_proximal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NPPC FAM181A FOXA1	1.08e-03	184	49	3	575de705053da8b289670b5c40c1627c0833b5ed
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 NPPC MSC	1.10e-03	185	49	3	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPPC COL11A2 AMOTL1	1.10e-03	185	49	3	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	SPN INHBA MARCO	1.10e-03	185	49	3	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPPC COL11A2 AMOTL1	1.10e-03	185	49	3	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	metastatic_Brain-Myeloid_cells-Alveolar_Mac\|metastatic_Brain / Location, Cell class and cell subclass	SPN INHBA MARCO	1.11e-03	186	49	3	9270e04c61b743874424a5935537b62e7d89c461
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	INHBA DOCK10 MARCO	1.11e-03	186	49	3	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	wk_20-22-Hematologic-Myeloid-Myelocyte-like\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ZSWIM8 RUNDC3B INHBA	1.11e-03	186	49	3	53b4ce33ae6fa32f1b56cbc62b1d7915e935afc9
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	SPN INHBA MARCO	1.11e-03	186	49	3	ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INHBA DOCK10 MARCO	1.11e-03	186	49	3	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXA1 SOCS7 ZNF687	1.13e-03	187	49	3	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXA1 SOCS7 ZNF687	1.13e-03	187	49	3	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPPC MSC RRP9	1.13e-03	187	49	3	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	metastatic_Brain-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SPN INHBA MARCO	1.13e-03	187	49	3	7375f70a970a5d5a58b7c33ada2dcf6dcef525c6
ToppCell	HSPCs-Ery/Mk_prog.\|World / Lineage and Cell class	SOX4 SERBP1 HNRNPU	1.15e-03	188	49	3	5390089213cd6ee90dcdfd3c3f5b6765376cccf2
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX4 FMN2 CLASP2	1.15e-03	188	49	3	459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX4 FMN2 CLASP2	1.15e-03	188	49	3	9fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCell	MS-CD8-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	RRP9 ZBTB22 IRGQ	1.15e-03	188	49	3	2f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPPC DOCK10 GDF11	1.17e-03	189	49	3	222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 MNX1 EN2	1.17e-03	189	49	3	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	368C-Myeloid-Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	SPN INHBA MARCO	1.17e-03	189	49	3	e62355be0d136e2b7c739848022292e9c6af7392
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Control / Disease state, Lineage and Cell class	SPN INHBA MARCO	1.17e-03	189	49	3	937e876122bc4b94372a4104e9c1a9068c232018
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|IPF / Disease state, Lineage and Cell class	SPN INHBA MARCO	1.18e-03	190	49	3	e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	INHBA AMOTL1 MARCO	1.18e-03	190	49	3	0eef5a8bd88ef8a25a67d9dd522d9472fa4b3d2f
Drug	Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A	SPN IRGQ EN2 YY1 PDCD4 HNRNPU	3.65e-06	194	49	6	4126_DN
Drug	AC1L1AXZ	MNX1 PDX1 EN2	2.95e-05	28	49	3	CID000001200
Drug	Piperlongumine [20069-09-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	SOX4 ZSWIM8 POGZ IRGQ PDCD4	3.98e-05	178	49	5	2757_DN
Drug	valnoctamide	SOX4 MNX1 YY1	4.04e-05	31	49	3	CID000020140
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	SOX4 SPN YY1 PDCD4 HNRNPU	6.15e-05	195	49	5	4106_DN
Drug	6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A	SOX4 SPN DOCK10 YY1 PDCD4	6.30e-05	196	49	5	2925_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	SOX4 SPN MNX1 INHBA EN2	6.45e-05	197	49	5	1806_DN
Drug	Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	SOX4 RUNDC3B RRP9 POGZ WIPF2	6.61e-05	198	49	5	4825_DN
Drug	Droperidol [548-73-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SOX4 MNX1 IRGQ YY1 WIPF2	6.61e-05	198	49	5	5690_DN
Drug	Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; HL60; HT_HG-U133A	SOX4 SPN DOCK10 PRDM13 GDF11	6.61e-05	198	49	5	1341_DN
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A	SOX4 SPN DOCK10 YY1 PDCD4	6.77e-05	199	49	5	4278_DN
Disease	Cartilage Diseases	NPPC COL11A2	3.71e-05	6	47	2	C0007302
Disease	Chondromalacia	NPPC COL11A2	3.71e-05	6	47	2	C0085700
Disease	Anorectal Malformations	SOX4 MNX1 AMOTL1	3.87e-05	41	47	3	C3495676
Disease	Intellectual Disability	SOX4 PRR12 POGZ YY1 HNRNPU SYNGAP1	7.42e-05	447	47	6	C3714756
Disease	Neurodevelopmental Disorders	POGZ HNRNPU SYNGAP1	4.44e-04	93	47	3	C1535926
Disease	Dysphagia	PRMT6 CHMP4B	6.70e-04	24	47	2	HP_0002015
Disease	Neonatal diabetes mellitus	MNX1 PDX1	7.28e-04	25	47	2	C0158981
Disease	Epileptic encephalopathy	HNRNPU SYNGAP1	1.05e-03	30	47	2	C0543888

Protein segments in the cluster

Peptide	Gene	Start	Entry
EGSGGGPKGGTADKG	MLLT6	1071	P55198
GGGGSGGGKREDKKL	GJD2	131	Q9UKL4
GGGGGGKRGGKKDDS	AFG3L2	111	Q9Y4W6
GSGNGKGFKVGGGPS	AMOTL1	281	Q8IY63
KLFGAGGGKAGKGGP	CHMP4B	6	Q9H444
AGGGQKKGDKAPGGG	NPPC	46	P23582
EGGGGGGGMEKSSGP	CDV3	126	Q9UKY7
EGEGKKKGGGEGGAG	INHBA	266	P08476
NKKKEAGGGGVGGPG	SERBP1	36	Q8NC51
MSGRGKGGKGLGKGG	H4C1	1	P62805
GSGGDKGSGFPDGEG	SPN	321	P16150
EKQKGGGGGAGKGGA	MNX1	311	P50219
DKKRGGGTAVGGGGV	PDX1	206	P52945
SGKGRGLPKKGGAGG	PDCD4	106	Q53EL6
GGKKKAEGGGGGGRP	HNRNPU	211	Q00839
KGGGGGGGTAPEKPD	FOXL2	36	P58012
GKSGAKGTSGGDGPH	COL11A2	856	P13942
PGSEGRQGGKGAKGD	COL11A2	1326	P13942
FKCEKQPGAGGGGGS	FOXA1	266	P55317
DKYGKEGLNGGGGGG	DNAJB6	66	O75190
SKGGGGAGGTGVFKS	DOCK10	171	Q96BY6
KPLTGEGTAGGGGGG	GDF11	201	O95390
KRKLESGGGGEGGEG	PRMT6	6	Q96LA8
TPGPQGEKGSKGDGG	MARCO	221	Q9UEW3
GAKKGGDPGGPLDGS	EN2	166	P19622
GKKALGKHGKGGGGG	FMN2	41	Q9NZ56
TGGGGSGGSGAGKPK	PRDM13	556	Q9H4Q3
GSQKAGSGEGPGKAG	IRGQ	376	Q8WZA9
DSGERGGKGQKGEGG	OTOL1	246	A6NHN0
GPDSSPGGGGGCKEK	FAM181A	146	Q8N9Y4
KNSGGGKGSGSGKGS	IRS4	586	O14654
GKGSGSGKGSDGDGE	IRS4	591	O14654
GAAGGTGGGGARPVK	GAREM2	196	Q75VX8
GIRGGGGGGGKKSLS	RUNDC3B	11	Q96NL0
PGEKGDKVGGSGGGG	SOX4	151	Q06945
ELASGGGGSGGVGKK	POGZ	956	Q7Z3K3
KDGGGEEKDGGGAGV	RHOXF2B	71	P0C7M4
KGKGDGSELLAGPGG	PRR12	616	Q9ULL5
SGGHGPGGGKKDDKD	PSMC1	6	P62191
GSAGGPKVGGASKEG	CLASP2	46	O75122
GGGSGGKGKGGCPAV	SYNGAP1	386	Q96PV0
GKPASGAGAGAGAGK	RRP9	11	O43818
GGGSSSSGGGRVKKG	YY1	161	P25490
KDGGGEEKDGGGAGV	RHOXF2	71	Q9BQY4
GSGGGDGTGKRPSGE	SOCS7	226	O14512
GGGKAKALGGAGSGS	ZSWIM8	581	A7E2V4
KDTDVGGGGKGTGGA	ZNF503	256	Q96F45
RELGSKGLKGGGGGP	ZNF687	946	Q8N1G0
KPKGSSGGYGSGGAA	WIPF2	66	Q8TF74
GGVPGGTGSGDGNKI	ZBTB22	471	O15209
GGAGGSAGGGGKKPL	MSC	81	O60682