Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmethylated histone binding

SPIN1 SPIN2A SPIN2B SPIN3

7.42e-0586524GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

SPIN1 SPIN2A SPIN2B SPIN3

8.11e-0588524GO:0140034
GeneOntologyMolecularFunctionXMP 5'-nucleosidase activity

NT5C1A NT5C1B

1.84e-048522GO:0106411
GeneOntologyMolecularFunction5'-nucleotidase activity

NT5C1A NT5C1B

6.83e-0415522GO:0008253
GeneOntologyMolecularFunctionnucleotidase activity

NT5C1A NT5C1B

9.91e-0418522GO:0008252
GeneOntologyCellularComponentintraciliary transport particle A

TTC21A WDR35

1.68e-048522GO:0030991
DomainSpin-Ssty

SPIN1 SPIN2A SPIN2B SPIN3

2.67e-105524PF02513
DomainSPIN/Ssty

SPIN1 SPIN2A SPIN2B SPIN3

2.67e-105524IPR003671
DomainTPR-like_helical_dom

CLTCL1 TTC28 TTC21A WDR35 TTC22 IFIT1 NAA16

3.57e-06233527IPR011990
DomainTPR_1

TTC28 TTC21A TTC22 IFIT1 NAA16

5.05e-0690525PF00515
DomainTPR_1

TTC28 TTC21A TTC22 IFIT1 NAA16

5.05e-0690525IPR001440
DomainSPIN-2

SPIN2A SPIN2B

7.60e-062522IPR029564
Domain5-nucleotidase

NT5C1A NT5C1B

2.28e-053522PF06189
Domain5-nucleotidase

NT5C1A NT5C1B

2.28e-053522IPR010394
Domain-

CLTCL1 TTC28 TTC21A TTC22 IFIT1 NAA16

2.29e-052075261.25.40.10
DomainTPR

TTC28 TTC21A TTC22 IFIT1 NAA16

2.91e-05129525SM00028
DomainTPR_repeat

TTC28 TTC21A TTC22 IFIT1 NAA16

3.37e-05133525IPR019734
DomainTPR-contain_dom

TTC28 TTC21A TTC22 IFIT1 NAA16

5.99e-05150525IPR013026
DomainTPR_REGION

TTC28 TTC21A TTC22 IFIT1 NAA16

9.41e-05165525PS50293
DomainTPR

TTC28 TTC21A TTC22 IFIT1 NAA16

9.41e-05165525PS50005
DomainIntegrin_bsu_cyt_dom

ITGB2 ITGB5

1.13e-046522IPR014836
DomainIntegrin_b_cyt

ITGB2 ITGB5

1.13e-046522SM01241
DomainIntegrin_b_cyt

ITGB2 ITGB5

1.13e-046522PF08725
DomainIntegrin_bsu_tail

ITGB2 ITGB5

1.58e-047522IPR012896
DomainIntegrin_B_tail

ITGB2 ITGB5

1.58e-047522SM01242
DomainIntegrin_B_tail

ITGB2 ITGB5

1.58e-047522PF07965
DomainIntegrin_beta

ITGB2 ITGB5

2.11e-048522PF00362
DomainINB

ITGB2 ITGB5

2.11e-048522SM00187
DomainIntegrin_bsu_VWA

ITGB2 ITGB5

2.11e-048522IPR002369
DomainPSI

PLXNB2 ITGB2 ITGB5

2.49e-0444523IPR016201
DomainIntegrin_bsu

ITGB2 ITGB5

2.70e-049522IPR015812
DomainIntegin_beta_N

ITGB2 ITGB5

2.70e-049522IPR033760
DomainINTEGRIN_BETA

ITGB2 ITGB5

2.70e-049522PS00243
DomainPSI_integrin

ITGB2 ITGB5

2.70e-049522PF17205
DomainPSI

PLXNB2 ITGB2 ITGB5

2.84e-0446523SM00423
DomainTPR_8

TTC28 TTC21A IFIT1

4.32e-0453523PF13181
DomainEF_Hand_1_Ca_BS

DST PLCH1 KCNIP1 DNAH7

1.42e-03175524IPR018247
DomainIntegrin_dom

ITGB2 ITGB5

2.19e-0325522IPR032695
DomainKinase-like_dom

SMG1 DST NEK10 MINK1 DCLK3 EPHB1

3.81e-03542526IPR011009
DomainEF_hand_dom

DST PLCH1 KCNIP1 DNAH7

3.94e-03232524IPR002048
DomainTPR_2

TTC28 NAA16

8.55e-0350522PF07719
Pubmed

A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.

SPIN1 SPIN2A SPIN2B SPIN3

6.65e-11652429061846
Pubmed

Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.

SPIN2A SPIN2B

2.19e-06252212145692
Pubmed

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.

KL ZBTB20

6.57e-06352225673831
Pubmed

Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein.

NT5C1A NT5C1B

1.31e-05452211690631
Pubmed

Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit.

ITGB2 ITGB5

2.19e-0555229442085
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 CUX2 DST TTC28 WDR35

2.20e-0522552512168954
Pubmed

HIV-1-Tat protein promotes chemotaxis and invasive behavior by monocytes.

ITGB2 ITGB5

3.28e-0565228757599
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

DST TTC28 SSX2IP ATG2B TACC2 RABGAP1 PLXNB2 IFIT1 GRSF1 EXOC4

6.38e-051496521032877691
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST NBEA RABGAP1 EXOC4

7.86e-0515152417043677
Pubmed

An evolutionarily conserved Lhx2-Ldb1 interaction regulates the acquisition of hippocampal cell fate and regional identity.

ZBTB20 EPHB1

9.79e-051052232994168
Pubmed

Integrins.

ITGB2 ITGB5

1.43e-041252219693543
Pubmed

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.

ITGB2 ITGB5

1.43e-041252212606711
Pubmed

HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons.

CUX2 ITGB2

1.97e-041452227650319
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DST TTC28 SSX2IP ATG2B

2.74e-0420952436779422
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DST TTC28 MINK1 SSX2IP PLCH1 DNAH7 EXOC4

2.82e-0486152736931259
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DST TTC28 ATG2B RABGAP1 EXOC4

4.00e-0441852534709266
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 DST TTC28 MINK1 PLCH1 EXOC4

4.08e-0465052638777146
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DST MINK1 PLCH1 PLXNB2 EXOC4

4.13e-0442152536976175
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DST TTC28 MINK1 ATG2B PLCH1 EXOC4

6.40e-0470852639231216
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

CCNB2 MINK1 ATG2B PLCH1 EXOC4

6.61e-0446752530194290
Pubmed

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.

DST NBEA

6.96e-042652226857994
Pubmed

Same but different - Molecular comparison of human KTI12 and PSTK.

ATG2B SPIN3

7.51e-042752233417976
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGB2 ITGB5

7.51e-042752231541017
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

CUX2 PHF10

8.08e-042852223643363
Pubmed

Regulation of archicortical arealization by the transcription factor Zbtb20.

ZBTB20 EPHB1

8.08e-042852222689450
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DST TTC28 MINK1 NBEA DNAH7 GRSF1

1.04e-0377752635844135
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

ITGB2 ITGB5

1.06e-033252223154389
Pubmed

Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus.

CUX2 ZBTB20

1.06e-033252220308569
Pubmed

DNA cloning using in vitro site-specific recombination.

ZBTB20 CCNB2 SPIN1 SSX2IP GRM1 EXOC4

1.16e-0379452611076863
InteractionCDY2A interactions

CLTCL1 SPIN1 SPIN2A SPIN3

1.94e-0721504int:CDY2A
InteractionDEFB107A interactions

SPIN1 SPIN2B SPIN3

4.04e-0613503int:DEFB107A
CytobandXp11.1

SPIN2A SPIN2B

7.54e-064522Xp11.1
Cytoband3p22.2

TTC21A DCLK3

3.42e-04245223p22.2
GeneFamilyTudor domain containing|Spindlin family

SPIN1 SPIN2A SPIN2B SPIN3

1.03e-1054041089
GeneFamilyTudor domain containing

SPIN1 SPIN2A SPIN2B SPIN3

1.29e-0637404780
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC28 TTC21A TTC22 IFIT1 NAA16

5.25e-06115405769
GeneFamilyCD molecules|5'-nucleotidases

NT5C1A NT5C1B

9.95e-0574021042
GeneFamilyCD molecules|Integrin beta subunits

ITGB2 ITGB5

1.70e-0494021159
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

TTC21A WDR35

1.28e-0324402615
GeneFamilyEF-hand domain containing

DST PLCH1 KCNIP1 DNAH7

1.36e-03219404863
CoexpressionAtlaskidney_P1_CapMes_Crym_top-relative-expression-ranked_500

CUX2 ZBTB20 DST TTC28 PLCH1 SPIN2B UST

4.13e-06276517gudmap_kidney_P1_CapMes_Crym_500
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_500

CUX2 ZBTB20 DST TTC28 PLCH1 SPIN2B UST

6.24e-06294517gudmap_kidney_P0_CapMes_Crym_500
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_1000

CUX2 ZBTB20 DST TTC28 MINK1 WDR35 PLCH1 SPIN2B UST

1.88e-05639519gudmap_kidney_P0_CapMes_Crym_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_100

CUX2 ZBTB20 PLCH1 SPIN2B

6.20e-0589514gudmap_kidney_P3_CapMes_Crym_100
CoexpressionAtlasMESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05

CUX2 TTC28 SPIN2A WDR35 NBEA PLCH1 SPIN2B RNF145 KCNIP1 PHF10 NAA16

1.46e-0412455111PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SPATA6L NEK10 NBEA TACC2 PLCH1 DNAH7

1.06e-07195526fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SPATA6L NEK10 NBEA TACC2 PLCH1 DNAH7

1.06e-07195526eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NT5C1A ZBTB20 GRM1 KCNIP1 IFIT1

1.21e-06160525dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA6L NEK10 TTC21A NBEA DNAH7

3.12e-061945254a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SPATA6L NEK10 TACC2 PLCH1 DNAH7

3.20e-0619552521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

SPATA6L NEK10 TACC2 PLCH1 DNAH7

3.28e-0619652587d9881cfec461a5d89b688a83749b618c519485
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEK10 CCNB2 TTC21A PLCH1 DNAH7

3.36e-061975256e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

NEK10 TTC21A WDR35 PLCH1 DNAH7

3.45e-061985256d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

CUX2 ZBTB20 PLCH1 KCNIP1 ITGB5

3.62e-06200525f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CUX2 ZBTB20 PLCH1 KCNIP1 ITGB5

3.62e-0620052570a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

CUX2 ZBTB20 PLCH1 KCNIP1 ITGB5

3.62e-062005251639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NT5C1A GRM1 KCNIP1 IFIT1

1.43e-0512652494bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATG2B DNAJB7 GABRR3 EPHB1

2.99e-051525245adcdf93fd3ca066402aaaf308c363e4648f871d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NT5C1A GRM1 KCNIP1 IFIT1

3.14e-05154524a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NT5C1A GRM1 KCNIP1 IFIT1

3.23e-051555245c7b68b59244525e3714806c205a57a2daebf423
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NT5C1A ZBTB20 GRM1 IFIT1

3.74e-05161524bf70be1de418615b5442ec684552551edaf1f072
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZBTB20 NBEA KCNIP1 UST

3.74e-051615243b5d7a3dab479c6959a428f3954dedd989900276
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SMG1 ZBTB20 NT5C1B EXOC4

3.83e-05162524b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 TTC21A NBEA DNAH7

4.52e-0516952414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NBEA SPIN2B KCNIP1 IFIT1

4.95e-05173524b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CUX2 DST PLXNB2 EPHB1

5.29e-05176524ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST PLXNB2 IFIT1 ITGB5

5.41e-0517752426bad614560609d318bfc9c235a698bca4e1c22c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCH1 GRM1 KCNIP1 ITGB5

6.29e-051845247f6c8912677764d438ab0555faca344d74c2f483
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 PLCH1 KCNIP1 UST

6.29e-05184524658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCH1 GRM1 KCNIP1 ITGB5

6.69e-0518752485f1678338a47d91e296f0620d4887f057eb7e70
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

SPATA6L TACC2 PLCH1 RNF145

6.83e-05188524707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPATA6L TACC2 PLCH1 RNF145

7.12e-0519052427a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CUX2 DST ITGB5 EPHB1

7.27e-051915241f4c8078e1a6cd14937c714330af608caced2acf
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SPATA6L NEK10 PLCH1 DNAH7

7.27e-0519152460ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPATA6L TACC2 PLCH1 RNF145

7.27e-05191524e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

NEK10 TTC21A NBEA DNAH7

7.41e-051925249cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA6L NEK10 PLCH1 DNAH7

7.41e-05192524d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA6L NEK10 PLCH1 DNAH7

7.41e-05192524eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

SPATA6L NEK10 PLCH1 DNAH7

7.41e-05192524354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCH1 KCNIP1 UST ITGB5

7.56e-05193524c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA6L NEK10 TTC21A DNAH7

7.56e-05193524ea345d34440b25f65358a53dc72831998d1c3620
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCH1 GRM1 KCNIP1 ITGB5

7.56e-05193524e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

CUX2 TTC28 DCLK3 EXOC4

7.56e-051935243b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

CUX2 NBEA PLXNB2 EPHB1

7.72e-051945245f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA6L NEK10 PLCH1 DNAH7

7.72e-051945241ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA6L NEK10 PLCH1 DNAH7

7.72e-05194524958e648138676d46698090b4046cb484083ae449
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCH1 KCNIP1 UST ITGB5

7.72e-051945241bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 TTC21A NBEA DNAH7

7.87e-05195524649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 TTC21A NBEA DNAH7

7.87e-05195524129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 TTC21A NBEA DNAH7

7.87e-051955243e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA6L NEK10 TTC21A DNAH7

7.87e-05195524e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

SPATA6L NEK10 TTC21A DNAH7

7.87e-0519552460067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB20 TTC28 UST EXOC4

8.03e-05196524ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

CUX2 ZBTB20 TTC28 EPHB1

8.03e-051965249401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA6L NEK10 TTC21A DNAH7

8.03e-05196524d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA6L NEK10 TTC21A DNAH7

8.19e-0519752471fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA6L NEK10 TTC21A DNAH7

8.19e-0519752474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA6L NEK10 TTC21A DNAH7

8.19e-05197524e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA6L NEK10 TTC21A DNAH7

8.19e-05197524d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

CUX2 TTC28 ATG2B EPHB1

8.35e-05198524fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB20 TTC28 UST EXOC4

8.35e-051985241996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPATA6L TACC2 PLCH1 RNF145

8.51e-051995245cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB20 TTC28 NBEA EXOC4

8.51e-0519952494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEK10 TTC21A PLCH1 DNAH7

8.68e-0520052431d75c26055177d656df1fbb10b764cebd61e122
Druglithium indium

SPIN2A SPIN2B

5.12e-062522CID011116062
Drugscandium phosphate

SPIN2A SPIN2B

5.12e-062522CID006365269
Drugrubidium nitrate

SPIN2A SPIN2B

5.12e-062522CID000025731
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

PLXNB2 GABRR3 NAA16

8.98e-0549523DOID:0060037 (implicated_via_orthology)
Diseasep-tau:beta-amyloid 1-42 ratio measurement

TTC28 PRDM6

5.11e-0419522EFO_0007709
DiseaseInfiltrating duct carcinoma of female breast

SMG1 DCLK3

6.26e-0421522C3165106
Diseasepulse pressure measurement

CUX2 TTC28 NEK10 SF3A3 NBEA RABGAP1 PLXNB2 ITGB5 PRDM6

6.63e-041392529EFO_0005763
Diseasebreast cancer, COVID-19

CUX2 TTC28

6.88e-0422522MONDO_0007254, MONDO_0100096
Diseasecancer (implicated_via_orthology)

CUX2 DST ITGB2 ITGB5

1.28e-03268524DOID:162 (implicated_via_orthology)
Diseaseascending aortic diameter

DUS2 KCNIP1 PRDM6

1.95e-03140523EFO_0021787
Diseasediverticulitis

NBEA UST

1.95e-0337522EFO_1001460
DiseaseMicrocalcification

KL ITGB2

2.51e-0342522C0521174
DiseaseCalcinosis

KL ITGB2

2.51e-0342522C0006663
DiseaseTumoral calcinosis

KL ITGB2

2.51e-0342522C0263628
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

ZBTB20 TTC28 MINK1 NBEA TACC2 EPHB1

2.76e-03801526EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseGastric Adenocarcinoma

MINK1 EPHB1

2.87e-0345522C0278701

Protein segments in the cluster

PeptideGeneStartEntry
IYEQEGLEKYMEYQL

NT5C1B

326

Q96P26
IERERDMEIAEYYGY

C2orf78

906

A6NCI8
YTEQGVEEYVRYQLE

NT5C1A

71

Q9BXI3
NEDEMYKILLNDYEY

SSX2IP

251

Q9Y2D8
EQYELYMYREVDTLE

CUX2

886

O14529
EDEYRIQMELNRYYL

ATG2B

361

Q96BY7
YMGQRYVEVYEINNE

GRSF1

216

Q12849
YQLERLMQEYIPDLY

RABGAP1

696

Q9Y3P9
NGIILDYEIRYYEKE

EPHB1

461

P54762
LYVEEQEYLQAYEDV

DST

11

Q03001
YETDMEIYLILEYVQ

DCLK3

421

Q9C098
REDPNYYSYLEMDLQ

PLXNB2

251

O15031
LAQYMEIVANEYLGY

NEK10

161

Q6ZWH5
DYEYSELILYQNQVM

NAA16

186

Q6N069
RQVEDYPVDLYYLMD

ITGB5

131

P18084
YYQYQRDKIEDELEM

KCNIP1

26

Q9NZI2
YYLQLEDDIIAKEMY

MGAT4D

251

A6NG13
EELDYYLYGQQRMEI

PRDM6

171

Q9NQX0
EYYMLQEQVSEYLGV

PHF10

86

Q8WUB8
LEQQDGMDRYLIYVD

ITGB2

676

P05107
MVDYYEVLGLQRYAS

DNAJB7

1

Q7Z6W7
RQYYEMLYNTADELL

EXOC4

896

Q96A65
ELESYAYNEDDLMLY

GABRR3

201

A8MPY1
YYTGYTENEVLEVMQ

CCNB2

331

O95067
NYIQEILRNYMYEDF

DNAH7

2231

Q8WXX0
VYKLEGNMNEALEYY

IFIT1

446

P09914
AEDDQLRVYYMQNYI

KL

881

Q9UEF7
EEVMQKYIRYAVQYD

DUS2

261

Q9NX74
IMNLQYTEANRYDYV

GRM1

481

Q13255
MLLCYEDEGVYVNTY

MINK1

1226

Q8N4C8
DVYLGVYLMNQYLET

SPATA6L

26

Q8N4H0
YMPLRDDYEIEYDQD

TADA2B

166

Q86TJ2
EYLAKMYEEYQRQEE

NBEA

956

Q8NFP9
YLENLEKLMYNAYEG

SMG1

986

Q96Q15
VLYMYQLLDDYKEGD

SPIN2A

171

Q99865
DELEELMCYYQDRGY

CLTCL1

1281

P53675
LMCYYQDRGYFEELI

CLTCL1

1286

P53675
QYEQTLMYGRYTQDL

CLCN2

16

P51788
PEAVQILYQRMRYEY

UST

331

Q9Y2C2
LYMYQLLDDYKEGDL

SPIN1

176

Q9Y657
VLYMYQLLDDYKDGD

SPIN3

171

Q5JUX0
VLYMYQLLDDYKEGD

SPIN2B

171

Q9BPZ2
ELDYRNSYEIEYMEK

TACC2

2516

O95359
YLMAQVRYYSELENA

TTC21A

506

Q8NDW8
EVYQDMDQPLCNYYI

PLCH1

296

Q4KWH8
QEMEDDYDYYGQQRV

ZBTB20

331

Q9HC78
YYEQYLRLAPDLQDM

TTC28

616

Q96AY4
EYKRYLEMLLEYLQD

SF3A3

181

Q12874
ILLQEYIMRDYGFVY

TGM7

156

Q96PF1
RLAECYYMLEDYEGL

WDR35

831

Q9P2L0
YYMLEDYEGLENLAI

WDR35

836

Q9P2L0
NMDDVIYYVNGTYRL

RNF145

446

Q96MT1
QVYYYMGVDAVQELL

TTC22

391

Q5TAA0
LSEHYEQMEYLGRYI

TMEM249

171

Q2WGJ8