Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainGPS

PKD1L1 ADGRG4 ADGRG6 ADGRF5

3.13e-0536944PS50221
DomainGPS

PKD1L1 ADGRG4 ADGRG6 ADGRF5

3.50e-0537944IPR000203
DomainADAM_spacer1

ADAMTS1 ADAMTS9 ADAMTS18

2.03e-0423943IPR010294
DomainADAM_spacer1

ADAMTS1 ADAMTS9 ADAMTS18

2.03e-0423943PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS1 ADAMTS9 ADAMTS18

2.31e-0424943IPR013273
DomainDMAP_binding

DIP2A DIP2C

2.48e-045942PF06464
DomainDMAP1-bd

DIP2A DIP2C

3.71e-046942IPR010506
DomainDMAP_binding

DIP2A DIP2C

3.71e-046942SM01137
DomainArm_3

KPNA5 KPNA1

5.18e-047942PF16186
DomainPKD

PKD1L1 SORCS2

5.18e-047942PF00801
DomainImporting_su_alpha

KPNA5 KPNA1

5.18e-047942IPR024931
DomainArm_3

KPNA5 KPNA1

5.18e-047942IPR032413
DomainIBB

KPNA5 KPNA1

5.18e-047942PF01749
DomainMFS_dom

SLC2A2 SLC2A10 SLC22A13 SLC49A3 MFSD13A

5.81e-04134945IPR020846
DomainGPS

ADGRG4 ADGRG6 ADGRF5

6.60e-0434943SM00303
DomainGPCR_2_secretin-like_CS

ADGRG4 ADGRG6 ADGRF5

6.60e-0434943IPR017983
DomainIBB

KPNA5 KPNA1

6.88e-048942PS51214
DomainGPS

ADGRG4 ADGRG6 ADGRF5

7.19e-0435943PF01825
DomainMetalloPept_cat_dom

ADAMTS1 ECE1 ADAMTS9 ADAMTS18

7.44e-0481944IPR024079
Domain-

ADAMTS1 ECE1 ADAMTS9 ADAMTS18

7.44e-04819443.40.390.10
DomainMFS_sugar_transport-like

SLC2A2 SLC2A10 SLC22A13

7.82e-0436943IPR005828
DomainSugar_tr

SLC2A2 SLC2A10 SLC22A13

7.82e-0436943PF00083
DomainConA-like_dom

MID2 TRIM65 ADGRG4 ADGRG6 THBS4 ALK

8.38e-04219946IPR013320
DomainImportin-a_IBB

KPNA5 KPNA1

8.82e-049942IPR002652
DomainPKD/Chitinase_dom

PKD1L1 SORCS2

8.82e-049942IPR022409
DomainPKD

PKD1L1 SORCS2

8.82e-049942SM00089
DomainPeptidase_M12B_N

ADAMTS1 ADAMTS9 ADAMTS18

9.89e-0439943IPR002870
DomainPep_M12B_propep

ADAMTS1 ADAMTS9 ADAMTS18

9.89e-0439943PF01562
DomainDISINTEGRIN_1

ADAMTS1 ADAMTS9 ADAMTS18

1.07e-0340943PS00427
DomainG_PROTEIN_RECEP_F2_1

ADGRG4 ADGRG6 ADGRF5

1.07e-0340943PS00649
DomainGPCR_2_extracellular_dom

ADGRG4 ADGRG6 ADGRF5

1.07e-0340943IPR001879
DomainReprolysin

ADAMTS1 ADAMTS9 ADAMTS18

1.07e-0340943PF01421
DomainARM_REPEAT

KPNA5 ARMC2 KPNA1

1.07e-0340943PS50176
DomainADAM_MEPRO

ADAMTS1 ADAMTS9 ADAMTS18

1.07e-0340943PS50215
DomainDISINTEGRIN_2

ADAMTS1 ADAMTS9 ADAMTS18

1.07e-0340943PS50214
DomainG_PROTEIN_RECEP_F2_3

ADGRG4 ADGRG6 ADGRF5

1.07e-0340943PS50227
DomainARM

KPNA5 ARMC2 KPNA1

1.07e-0340943SM00185
DomainPeptidase_M12B

ADAMTS1 ADAMTS9 ADAMTS18

1.07e-0340943IPR001590
DomainPTX

ADGRG4 ADGRG6

1.10e-0310942SM00159
DomainDisintegrin_dom

ADAMTS1 ADAMTS9 ADAMTS18

1.15e-0341943IPR001762
DomainPentaxin-related

ADGRG4 ADGRG6

1.34e-0311942IPR001759
DomainPentaxin

ADGRG4 ADGRG6

1.34e-0311942PF00354
DomainPKD

PKD1L1 SORCS2

1.34e-0311942PS50093
DomainPKD_dom

PKD1L1 SORCS2

1.34e-0311942IPR000601
Domain-

PKD1L1 SORCS2

1.34e-03119422.60.40.670
DomainZINC_PROTEASE

ADAMTS1 ECE1 ADAMTS9 ADAMTS18

1.51e-0398944PS00142
DomainArmadillo

KPNA5 ARMC2 KPNA1

1.71e-0347943IPR000225
DomainG_PROTEIN_RECEP_F2_2

ADGRG4 ADGRG6 ADGRF5

2.04e-0350943PS00650
Domain7tm_2

ADGRG4 ADGRG6 ADGRF5

2.04e-0350943PF00002
DomainMFS

SLC2A2 SLC2A10 SLC22A13 SLC49A3

2.16e-03108944PS50850
DomainSugar/inositol_transpt

SLC2A2 SLC2A10

2.19e-0314942IPR003663
DomainSUGAR_TRANSPORT_2

SLC2A2 SLC2A10

3.24e-0317942PS00217
DomainGPCR_2_secretin-like

ADGRG4 ADGRG6 ADGRF5

3.43e-0360943IPR000832
DomainGPCR_2-like

ADGRG4 ADGRG6 ADGRF5

3.43e-0360943IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRG4 ADGRG6 ADGRF5

3.60e-0361943PS50261
DomainTSP_1

ADAMTS1 ADAMTS9 ADAMTS18

3.94e-0363943PF00090
DomainPkinase_Tyr

EPHB2 TEX14 HASPIN ALK

4.10e-03129944PF07714
DomainTSP1

ADAMTS1 ADAMTS9 ADAMTS18

4.30e-0365943SM00209
DomainTSP1_rpt

ADAMTS1 ADAMTS9 ADAMTS18

4.30e-0365943IPR000884
DomainTSP1

ADAMTS1 ADAMTS9 ADAMTS18

4.30e-0365943PS50092
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS1 ADAMTS9 ADAMTS18

4.98e-0612100325770910
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

ADAMTS1 VIRMA ADAMTS9 NYNRIN SORCS2 ALPK3

5.57e-06153100610718198
Pubmed

Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.

DIP2A DIP2C

8.18e-062100212137943
Pubmed

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma.

MTOR ALK

8.18e-062100225228590
Pubmed

Homocysteine metabolites impair the PHF8/H4K20me1/mTOR/autophagy pathway by upregulating the expression of histone demethylase PHF8-targeting microRNAs in human vascular endothelial cells and mice.

PHF8 MTOR

8.18e-062100239323294
Pubmed

Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells.

PIEZO1 RUNX2

8.18e-062100232181967
Pubmed

Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function.

EPHB2 MYCBP2

8.18e-062100238289221
Pubmed

Regulation of karyopherin α1 and nuclear import by mammalian target of rapamycin.

MTOR KPNA1

8.18e-062100222399302
Pubmed

Abnormal expressions of ADAMTS-1, ADAMTS-9 and progesterone receptors are associated with lower oocyte maturation in women with polycystic ovary syndrome.

ADAMTS1 ADAMTS9

8.18e-062100230446843
Pubmed

Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1.

SLC2A2 SLC2A10

8.18e-062100211592815
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS1 ADAMTS9 ADAMTS18

1.26e-0516100330579834
Pubmed

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.

DDIT4L MTOR

2.45e-053100228246202
Pubmed

Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.

KPNA5 KPNA1

2.45e-053100220406804
Pubmed

CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.

DIP2A DIP2C

2.45e-053100217236128
Pubmed

Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.

SLC2A2 SLC2A10

2.45e-053100211247674
Pubmed

Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein.

KPNA5 KPNA1

2.45e-053100212740372
Pubmed

The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.

DDIT4L MTOR

2.45e-053100215632201
Pubmed

Fam3c modulates osteogenic differentiation by down-regulating Runx2.

RUNX2 FAM3C

2.45e-053100227914282
Pubmed

[Study on activation of AKT/mTOR pathway in anaplastic large cell lymphoma].

MTOR ALK

2.45e-053100219176054
Pubmed

Elucidating the mechanism of IL-1β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway.

PIEZO1 MTOR

2.45e-053100238134572
Pubmed

Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice.

PHF8 MTOR

2.45e-053100237477632
Pubmed

Differential gene expression of ADAMTS-1, ADAMTS-9 and TIMP-3 in periodontitis.

ADAMTS1 ADAMTS9

2.45e-053100236093887
Pubmed

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.

ATP6V0A1 MTOR

2.45e-053100224468901
Pubmed

Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.

PIEZO1 MTOR

2.45e-053100236112948
Pubmed

Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.

ADAMTS1 ADAMTS18

2.45e-053100228814085
Pubmed

ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.

ADAMTS9 MTOR

2.45e-053100222907434
Pubmed

ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.

ADAMTS1 ADAMTS9

2.45e-053100223562508
Pubmed

mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.

RUNX2 MTOR

2.45e-053100228686577
Pubmed

Expression analysis of genes encoding TEX11, TEX12, TEX14 and TEX15 in testis tissues of men with non-obstructive azoospermia.

TEX15 TEX14

4.89e-054100229932616
Pubmed

A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway.

KPNA5 KPNA1

4.89e-054100212610148
Pubmed

mTOR inhibition potentiates cytotoxicity of Vγ4 γδ T cells via up-regulating NKG2D and TNF-α.

KLRK1 MTOR

4.89e-054100227256566
Pubmed

Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.

ADAMTS9 ADAMTS18

4.89e-054100216507336
Pubmed

Genetic determinants of circulating sphingolipid concentrations in European populations.

ATP10D FADS3

4.89e-054100219798445
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRG4 ADGRG6 ADGRF5

7.98e-0529100315203201
Pubmed

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.

KPNA5 KPNA1

8.14e-055100219961612
Pubmed

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.

TRPC1 MTOR

8.14e-055100222446186
Pubmed

Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.

KPNA5 KPNA1

8.14e-055100217981117
Pubmed

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

KPNA5 KPNA1

8.14e-055100215929992
Pubmed

Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.

ADAMTS1 ADAMTS9

8.14e-055100222562232
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRG4 ADGRG6 ADGRF5

1.18e-0433100325713288
Pubmed

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import.

KPNA5 KPNA1

1.22e-04610028551560
Pubmed

Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.

KPNA5 KPNA1

1.22e-046100226491019
Pubmed

p17 and p17-containing gag precursors of input human immunodeficiency virus are transported into the nuclei of infected cells.

KPNA5 KPNA1

1.22e-04610022064827
Pubmed

Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in nondividing cells.

KPNA5 KPNA1

1.22e-04610029548947
Pubmed

The putative alpha helix 2 of human immunodeficiency virus type 1 Vpr contains a determinant which is responsible for the nuclear translocation of proviral DNA in growth-arrested cells.

KPNA5 KPNA1

1.22e-04610029557700
Pubmed

A role for human immunodeficiency virus type 1 Vpr during infection of peripheral blood mononuclear cells.

KPNA5 KPNA1

1.22e-04610029603322
Pubmed

CNI-H0294, a nuclear importation inhibitor of the human immunodeficiency virus type 1 genome, abrogates virus replication in infected activated peripheral blood mononuclear cells.

KPNA5 KPNA1

1.22e-04610029593140
Pubmed

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase.

KPNA5 KPNA1

1.22e-04610027585960
Pubmed

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

KPNA5 KPNA1

1.22e-04610028041786
Pubmed

The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes.

KPNA5 KPNA1

1.22e-04610028041734
Pubmed

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

KPNA5 KPNA1

1.22e-04610029303297
Pubmed

Inhibition of nuclear import by backbone cyclic peptidomimetics derived from the HIV-1 MA NLS sequence.

KPNA5 KPNA1

1.22e-046100211904219
Pubmed

Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages.

KPNA5 KPNA1

1.22e-04610029918876
Pubmed

Rheb and mTOR regulate neuronal polarity through Rap1B.

RAP1B MTOR

1.22e-046100218842593
Pubmed

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator.

KPNA5 KPNA1

1.22e-04610027859280
Pubmed

Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.

KPNA5 KPNA1

1.22e-04610028529100
Pubmed

Proteolytic cleavage of versican during cardiac cushion morphogenesis.

ADAMTS1 ADAMTS9

1.22e-046100216691565
Pubmed

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection.

KPNA5 KPNA1

1.22e-04610029008157
Pubmed

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal.

KPNA5 KPNA1

1.22e-046100215037073
Pubmed

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

KPNA5 KPNA1

1.22e-04610028876228
Pubmed

Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection.

KPNA5 KPNA1

1.22e-04610027745752
Pubmed

Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion.

KPNA5 KPNA1

1.22e-04610028659115
Pubmed

The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.

CEP192 NEDD1

1.22e-046100218207742
Pubmed

Galnt1 is required for normal heart valve development and cardiac function.

GALNT10 ADAMTS1 ADAMTS9

1.54e-0436100325615642
Pubmed

The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican.

ADAMTS1 ADAMTS9

1.70e-047100215599946
Pubmed

Active nuclear import and cytoplasmic retention of activation-induced deaminase.

KPNA5 KPNA1

1.70e-047100219412186
Pubmed

Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.

ADAMTS1 ADAMTS9

1.70e-047100223354118
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IFT172 CEP192 PHF8 CSMD3 VIRMA STRIP1 WDR47

1.80e-04407100712693553
Pubmed

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

ADAMTS1 ADAMTS9 ADAMTS18

1.81e-0438100318267097
Pubmed

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.

ADGRG4 ADGRF5

2.27e-048100212435584
Pubmed

Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.

KPNA5 KPNA1

2.27e-048100218187047
Pubmed

BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells.

KPNA5 KPNA1

2.27e-048100226052702
Pubmed

Blocking nuclear import of pre-integration complex: an emerging anti-HIV-1 drug discovery paradigm.

KPNA5 KPNA1

2.27e-048100220015032
Pubmed

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

KPNA5 KPNA1

2.27e-04810028552640
Pubmed

HIV-1 nuclear import: in search of a leader.

KPNA5 KPNA1

2.91e-049100210525473
Pubmed

HIV-1 infection requires a functional integrase NLS.

KPNA5 KPNA1

2.91e-049100211389849
Pubmed

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.

KPNA5 KPNA1

2.91e-04910029463369
Pubmed

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.

KPNA5 KPNA1

2.91e-049100212414950
Pubmed

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).

KPNA5 KPNA1

2.91e-049100215057270
Pubmed

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

KPNA5 KPNA1

2.91e-049100210366569
Pubmed

HIV-1 nuclear import: in search of a leader.

KPNA5 KPNA1

2.91e-04910029366553
Pubmed

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.

KPNA5 KPNA1

2.91e-049100210860744
Pubmed

Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.

RAP1B MTOR

2.91e-049100224337580
Pubmed

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.

KPNA5 KPNA1

2.91e-049100212368302
Pubmed

Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells.

KPNA5 KPNA1

2.91e-049100221326825
Pubmed

Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses.

KPNA5 KPNA1

2.91e-049100211035935
Pubmed

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway.

KPNA5 KPNA1

2.91e-04910029275210
Pubmed

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.

ADAMTS1 ADAMTS9

2.91e-049100223095891
Pubmed

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

KPNA5 KPNA1

2.91e-049100210888652
Pubmed

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.

KPNA5 KPNA1

2.91e-04910021631159
Pubmed

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells.

KPNA5 KPNA1

2.91e-04910028105392
Pubmed

Characterization of the nuclear import pathway for HIV-1 integrase.

KPNA5 KPNA1

2.91e-049100211278458
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

ADAMTS1 RUNX2 NEDD1 THBS4 PRG2

3.62e-04210100516537572
Pubmed

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase.

KPNA5 KPNA1

3.63e-041010029282826
Pubmed

CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.

CEP192 NEDD1

3.63e-0410100222895009
Pubmed

Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.

MYCBP2 FBXW5

4.43e-0411100225143387
Pubmed

The HIV-1 passage from cytoplasm to nucleus: the process involving a complex exchange between the components of HIV-1 and cellular machinery to access nucleus and successful integration.

KPNA5 KPNA1

4.43e-0411100222509482
Pubmed

HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr.

KPNA5 KPNA1

4.43e-041110029562972
Pubmed

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr.

KPNA5 KPNA1

5.30e-041210027494303
Pubmed

Acetylation-dependent regulation of Skp2 function.

KPNA5 KPNA1

5.30e-0412100222770219
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS1 ADAMTS9 ADAMTS18

3.58e-051962350
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG4 ADGRG6

2.40e-047622917
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KPNA5 ARMC2 KPNA1

4.30e-0443623409
GeneFamilyArmadillo repeat containing|Importins

KPNA5 KPNA1

1.71e-0318622596
GeneFamilyWD repeat domain containing

IFT172 NEDD1 WDR47 TBC1D31 FBXW5

2.03e-03262625362
ToppCellInt-URO-Lymphocyte-T_NK-CD8_TCM|Int-URO / Disease, Lineage and Cell Type

IL32 MID2 TMEM204 DDIT4L VWDE CD6

1.46e-06158996edcc5a26d4571b179f3ae538fed23b661e4677dd
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM204 OR51E1 FADS3 ADAMTS9 ADAMTS18 ADGRF5

2.91e-06178996360d7a987f91d6d721487a921824057ec31a7332
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL32 TMEM204 RUNX2 LINS1 PGAP1 ALK

3.31e-061829963a3ed195c15d33d46a2f395cb93018e4bba28353
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ATP6V0A1 ADAMTS1 PKD1L1 ATP10D NUP155 PLXNC1

3.64e-06185996e06a784a297f357f3f8e761c24fa70722048ab42
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 RUNX2 KLRK1 LINS1 DIP2A CD6

4.11e-06189996e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PKD1L1 MCMDC2 CSMD3 QPRT C1QA

4.34e-06108995695ed3f8cf637d767a6d79b0309d5ee82dfd063f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 TMEM204 MCMDC2 RUNX2 KLRK1 CD6

4.64e-06193996c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

TMEM204 DDIT4L CHRNG THBS4 PLXNC1 SORCS2

4.78e-0619499655b97095a7a17a312c616703d291738a0f806339
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB2 GALNT10 RAP1B ARMC2 FBXW5 GNAZ

5.53e-0619999686d4e5dd3bcc6bafa48fd0211dad39a2456b53be
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM204 ADAMTS1 ECE1 ERVMER34-1 BDKRB2 ADGRF5

5.53e-06199996463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / Treatment groups by lineage, cell group, cell type

ADAMTS1 ECE1 BDKRB2 ADGRG6 ADAMTS9 FAM3C

5.69e-06200996b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 RAP1B ADGRG4 KLRK1 DIP2A FBXW5

5.69e-062009962bd8c35484fe6b0bc0f9314216786baaa97d1e95
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KPNA5 GALNT10 IL32 MCMDC2 NYNRIN

1.48e-05139995d441c29852c28928ecb696b4b95e31b30c17116b
ToppCellfacs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECE1 BDKRB2 C21orf140 ADAMTS18 SAYSD1

2.58e-05156995bb64bf520cb74897a01c64924a85a1550df2b801
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

IL32 ADGRG6 DIP2A PGAP1 PARP15

2.58e-05156995afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 TEX14 QPRT SLC6A20 GNAZ

2.67e-051579953c6be6995c00c4cadbd209c66bf9a87c8c238652
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 TEX14 QPRT SLC6A20 GNAZ

2.67e-05157995662d5026e0e4249029fc6f3abc771d775d7bc3bb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 MID2 TMEM204 CD6 DIP2C

3.01e-05161995580153e131247e6ec12a1a920f050a0a763e7e87
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECE1 BDKRB2 C21orf140 ADAMTS18 SAYSD1

3.10e-051629951f1b93394b1f27cbb76b369c19b9313609edd577
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 SLC2A10 TBC1D31 SLC6A20 HASPIN

3.48e-0516699521ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

MCMDC2 C1orf167 VWDE ADGRG6 ALK

3.68e-0516899590b33962adb77d8326dee403712118398b4d1315
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

MCMDC2 C1orf167 VWDE ADGRG6 ALK

3.90e-0517099585c476e0bc496445e868a88849960598d97bdea2
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 TRPC1 RUNX2 FADS3 FAM3C

4.24e-05173995ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 TRPC1 RUNX2 FADS3 FAM3C

4.24e-0517399519a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellNasal_Brush-Epithelial-Basal_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

IL32 TMEM204 ADAMTS1 CSMD3 ADAMTS18

4.60e-05176995fc5787946f5a10056d326d070620575ae4081836
ToppCellNasal_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

IL32 TMEM204 ADAMTS1 CSMD3 ADAMTS18

4.60e-051769955daaba0853afe7d20d4635169ccd4f96e735b938
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM204 ECE1 OR51E1 ADAMTS18 ADGRF5

5.12e-0518099564956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM204 MYCBP2 PLXNC1 NYNRIN ADGRF5

5.12e-05180995dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM204 MYCBP2 PLXNC1 NYNRIN ADGRF5

5.12e-05180995423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS1 ECE1 ADAMTS9 PGAP1 DIP2C

5.39e-05182995ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR21 ECE1 ADGRG6 FADS3 FAM3C

5.39e-05182995aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

VWDE ADGRG6 SLC2A10 PRG2 NYNRIN

5.68e-05184995ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM204 ADAMTS1 ADAMTS9 PLXNC1 ADGRF5

5.82e-05185995742350093d90f96735dc73e3360cdd749bae63fd
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR21 ECE1 ADGRG6 FADS3 FAM3C

5.82e-05185995eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 STRIP1 ADGRG6 HASPIN ANO3

5.82e-05185995554c5d812197fbf66bf279fcc953277e926ade15
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS1 ECE1 ADAMTS9 PGAP1 DIP2C

5.82e-05185995e58a009aaf342be019a909747b1895d5987d4daf
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

OR51E1 ADAMTS9 ALPK3 ADAMTS18 ADGRF5

5.98e-05186995e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ADGRG6 FADS3 NYNRIN FAM3C

5.98e-05186995ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ADGRG6 FADS3 NYNRIN FAM3C

5.98e-05186995ed924852cd7132c8f6703522037dc22bd2c83193
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 DDIT4L ADGRG6 FADS3 ADAMTS9

6.13e-051879959aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

IL32 TMEM204 ADAMTS1 ECE1 ADAMTS9

6.13e-05187995febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ECE1 ADGRG6 FADS3 FAM3C

6.13e-051879957170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ECE1 ADGRG6 PLXNC1 ADGRF5

6.29e-051889954ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ECE1 ADGRG6 PLXNC1 ADGRF5

6.29e-05188995e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM204 B3GNT3 ECE1 ADAMTS9 ADGRF5

6.44e-05189995ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR21 ECE1 ADGRG6 FAM3C ADGRF5

6.44e-051899959da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellIPF-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

EPHB2 GALNT10 IL32 FADS3 ADAMTS9

6.44e-051899954178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM204 B3GNT3 ECE1 ADAMTS9 ADGRF5

6.44e-05189995e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM204 B3GNT3 ECE1 ADAMTS9 ADGRF5

6.44e-05189995f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ADGRG6 FADS3 NYNRIN FAM3C

6.61e-051909953b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR21 ECE1 ADGRG6 FAM3C ADGRF5

6.77e-051919953307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ECE1 ADGRG6 NYNRIN ADGRF5

6.77e-051919959fc674a58f20b47255e4457d5195c8cff17b0414
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ECE1 ADGRG6 FADS3 FAM3C

6.77e-051919956e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR21 ECE1 ADGRG6 FADS3 FAM3C

6.77e-05191995482db995930346be69072ace2fd78fd453e97fb5
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG6 OR51E1 ALPK3 ADAMTS18 ADGRF5

6.77e-05191995dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ECE1 ADGRG6 NYNRIN ADGRF5

6.77e-05191995c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS1 ECE1 BDKRB2 OR51E1 ADAMTS9

6.94e-05192995c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 TMEM204 RUNX2 KLRK1 CD6

7.11e-0519399595f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCellremission|World / disease stage, cell group and cell class

IL32 TMEM204 KLRK1 LINS1 CD6

7.11e-0519399586cfd0c230ba96a43d343216935952fff6a5254e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GALNT10 IL32 KLRK1 CD6 PARP15

7.11e-0519399500349d176fb6a46cbcc99c41d975651b6e9aaad4
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

ADAMTS1 ECE1 ADGRG6 ADAMTS9 ADGRF5

7.29e-05194995b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG6 OR51E1 ADAMTS9 ALPK3 ADGRF5

7.29e-05194995e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_12-13-Lymphocytic_T|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IL32 TMEM204 LINS1 CD6 TRAV22

7.29e-051949954abc925820d23793d6ebf83fd7df8e75b32f09b4
ToppCell10x5'v1-week_12-13-Lymphocytic_T-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IL32 TMEM204 LINS1 CD6 TRAV22

7.29e-05194995b1ed9b7ea9298dc3ce900a2c6b0a2ca6412f1f5f
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG6 OR51E1 ADAMTS9 ALPK3 ADGRF5

7.29e-05194995953578102ffc7b612ee8fce45e414750800fef5d
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical|TCGA-Thryoid / Sample_Type by Project: Shred V9

B3GNT3 RUNX2 ECE1 EHBP1L1 PLXNC1

7.29e-05194995b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM204 ADAMTS1 ECE1 ADGRG6 ADGRF5

7.47e-051959954658fb197657d7692ee344ae76b11b0210c418ba
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL32 TMEM204 ECE1 CD6 PGAP1

7.47e-051959956ddce0cce14f737e45b8f57802c6a8ad07686262
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL32 TMEM204 ECE1 CD6 PGAP1

7.47e-05195995e6212373cc3c6c98f76e104e2ac1afa68965cc5f
ToppCellEndothelial-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

IL32 TMEM204 ADAMTS1 ECE1 ADAMTS9

7.47e-05195995c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM204 ADAMTS1 BDKRB2 ADGRG6 ADAMTS9

7.47e-0519599553b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCellMild_COVID-19-T/NK-CD4+_T_2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IL32 TMEM204 ECE1 CD6 PGAP1

7.65e-05196995e50d03d8428dc4526e4607b6b4e99f0812a0ad31
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM204 ECE1 OR51E1 ADAMTS18 ADGRF5

7.65e-0519699573f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL32 TMEM204 ECE1 CD6 PGAP1

7.84e-051979950b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG6 ADAMTS9 ALPK3 ADAMTS18 ADGRF5

7.84e-051979954e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRRC66 KLRK1 DIP2A PGAP1 PARP15

7.84e-05197995e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 KLRK1 DIP2A CD6 FBXW5

7.84e-051979958e41e6cda38eace961cb1a56f4df24468c66b956
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERCC6L PIEZO1 TEX15 ADGRG6 ADAMTS9

7.84e-0519799576b61e60a757e58b465569538e632d6d9953e89a
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL32 ECE1 KLRK1 CD6 PGAP1

7.84e-05197995927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD3-NKT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL32 BTBD17 CD6 TRAV22 PARP15

7.84e-05197995e2e7bc8e6c45c987d91cc3ee504fc5af130a69fe
ToppCellMild-Lymphoid-T-CCR7+_T|Mild / Condition, Lineage, Cell class and cell subclass

IL32 TMEM204 ECE1 CD6 PGAP1

7.84e-05197995f23bd8f6ad011730699a5bb7211cd0feeaebc42b
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD3|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL32 BTBD17 CD6 TRAV22 PARP15

7.84e-0519799546f82cce0f3c3ddb087953949e76aae19dc8bbf3
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL32 TMEM204 ECE1 CD6 PGAP1

7.84e-05197995b3876076684781fb8384117f2cf367d828985986
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL32 ECE1 KLRK1 CD6 PGAP1

7.84e-051979953e09158507df08c08e08613ce23617206280c911
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 OR51E1 FADS3 ADAMTS9 ALPK3

8.03e-051989957dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM204 ADAMTS9 ALPK3 ADAMTS18 ADGRF5

8.03e-05198995122215d9288533ad03562cf777e846504863df9a
ToppCellTransverse-B_cell-B_cell_IgG_Plasma|Transverse / Region, Cell class and subclass

TBC1D30 TEX14 ERVMER34-1 QPRT FAM3C

8.03e-05198995a4ece1fe3d15acfde0e6ff14cddb3a3d16f61ce0
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM204 ADAMTS9 ALPK3 ADAMTS18 ADGRF5

8.03e-05198995307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL32 TMEM204 ECE1 CD6 PGAP1

8.03e-051989956c375fc7e53ed7b7b0feba459958d177a65f7272
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM204 ADAMTS1 ECE1 ADGRG6 ADAMTS9

8.03e-05198995531b0f88c95f813e3914c96749f591e80ca321d0
ToppCellTransverse-(2)_B_cell-(21)_B_cell_IgG_Plasma|Transverse / shred on region, Cell_type, and subtype

TBC1D30 TEX14 ERVMER34-1 QPRT FAM3C

8.03e-05198995d6052b5a44246798e90f4779cd940ffac7539fcd
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRPC1 DDIT4L CSMD3 WDR47 THBS4

8.22e-05199995fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

IL32 TMEM204 ECE1 ALPK3 ADGRF5

8.22e-05199995b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

IL32 TMEM204 ECE1 ALPK3 ADGRF5

8.22e-051999950b4edf3e359749827ef978a77b5267ddde732d71
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

IL32 TMEM204 ECE1 ALPK3 ADGRF5

8.22e-051999959e01eee126247a0696c71b019f855a8a41a0ede3
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 ADGRG6 ADAMTS9 ADAMTS18 ADGRF5

8.22e-051999950d63da0afa93741c37609d879941de202d9ac86c
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL32 TMEM204 ADAMTS9 ALPK3 ADGRF5

8.22e-051999951c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellTracheal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 OR51E1 FADS3 ADGRF5 ANO3

8.22e-05199995cefc3b50f65e95da850e4720c7b44bf584073491
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL32 TMEM204 ECE1 CD6 PGAP1

8.22e-05199995ee29b65a3c545a9d19c2fbcc0364ee235dd018dc
ToppCellTracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE1B ADAMTS1 OR51E1 FADS3 ANO3

8.22e-05199995aaa460c389cd6d38a13ba1a446f91a94f9573ad8
DrugAminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A

KPNA5 TBC1D30 PHF8 ALPK3 SAYSD1 MFSD13A ALK

1.83e-051969573726_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A

EPHB2 KPNA5 MID2 TEX14 ATP10D TTLL4 SAYSD1

1.83e-051969575276_DN
DrugCloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A

ZNF219 TBC1D30 B3GNT3 EHBP1L1 CD6 PLXNC1 SAYSD1

2.02e-051999572289_DN
DrugSuloctidil [54063-56-8]; Down 200; 11.8uM; PC3; HT_HG-U133A

EPHB2 ZNF219 B3GNT3 PLXNC1 PGAP1 SAYSD1 ALK

2.02e-051999576675_DN
DrugHesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A

EPHB2 ECE1 ATP10D PLXNC1 NYNRIN PGAP1 ALK

2.02e-051999571531_UP
Diseasecomplement C1q subcomponent subunit C measurement

EPHB2 C1QA

4.73e-0410972EFO_0801492
Diseasepulmonary hypertension (implicated_via_orthology)

ECE1 BDKRB2 MTOR

7.56e-0454973DOID:6432 (implicated_via_orthology)
Diseaseearly cardiac repolarization measurement

KPNA5 MYCBP2

9.49e-0414972EFO_0004885
Diseaselipid metabolism disorder (implicated_via_orthology)

FADS2B FADS3

1.09e-0315972DOID:3146 (implicated_via_orthology)
Diseaseamygdala volume change measurement

PKD1L1 SPATA31C1

1.25e-0316972EFO_0021490
Diseaseportal hypertension (implicated_via_orthology)

BDKRB2 MTOR

1.76e-0319972DOID:10762 (implicated_via_orthology)
Diseaseatrophic macular degeneration

TEX15 PRG2

3.05e-0325972EFO_1001492

Protein segments in the cluster

PeptideGeneStartEntry
WFIINNRNEFCLQSI

C21orf140

191

B9A014
TISNNFDWLFGETLC

BDKRB2

116

P30411
LQALQLAVFFLWCQQ

C1orf167

621

Q5SNV9
RFQLQCDWNTSDFSI

ERVK-19

546

O71037
LTCIANSVNTASWDF

CSMD3

216

Q7Z407
FTFQVLSQWEICLSI

C1QA

161

P02745
NLVFLINSWLSSFQK

ADGRG4

2791

Q8IZF6
WQNCSLIFQSQTYST

CHRNG

161

P07510
FAESFEQLCLVWNNS

ADGRG6

246

Q86SQ4
VCKTLWNFSENITNA

ARMC2

781

Q8NEN0
ESCLQFLAWNLSAVA

BTBD17

186

A6NE02
LWCQFFNILSDSVLT

ALPK3

1496

Q96L96
WTFVNDSLCTTLSLQ

CCNK

186

O75909
LTLVFKQENCSWTSF

DDIT4L

136

Q96D03
SLQKQFLELTSWCQA

ATP10D

1011

Q9P241
ADQSLNSFCQWQSAL

ADAMTS18

361

Q8TE60
WQFATSAAAVCINFI

ANO3

591

Q9BYT9
NCTLQFEAAWALTNI

KPNA5

141

O15131
RQWNNCAFLESSAKS

RAP1B

136

P61224
VTSNAALTLRNFCNW

ADAMTS1

321

Q9UHI8
SWRFNNSNLCSQSLA

CD6

341

P30203
TSITNLGFRDNWVFC

FAM3C

171

Q92520
CQAFLDEFTNWSRIN

PARP15

256

Q460N3
LSNSWIAFCQKNLSE

LINS1

166

Q8NG48
SSCWKFTAILANIFA

MCMDC2

296

Q4G0Z9
GISSICWSSNNNFLV

NEDD1

36

Q8NHV4
CNSFNWAANLFISLS

SLC2A10

451

O95528
NTCNPSSLTQQWLFE

GALNT10

576

Q86SR1
VFRTLSILTNQSNCW

ERVMER34-1

31

Q9H9K5
VCNVFESSQNNWLRT

EPHB2

61

P29323
DITSCSVLWLNNAFQ

FBXW5

211

Q969U6
WNLSDRFNFTNCSSL

PLXNC1

581

O60486
IFWFNSTTIQFDACL

OR51E1

86

Q8TCB6
LDLWCFDVFSLNQAA

PDE1B

161

Q01064
VTIWSAVFLNSLFNQ

KLRK1

71

P26718
LAIAAFSNWTCNFIV

SLC2A2

436

P11168
FSNWTCNFIVALCFQ

SLC2A2

441

P11168
NFTTSWRNGLAFCAI

EHBP1L1

1061

Q8N3D4
DAIFTQLNCQVSWFL

QPRT

61

Q15274
WQCDDSVAVFQNFIS

LRRC66

256

Q68CR7
FIVQFLEQQVCTLNW

NUP155

1266

O75694
CNKFIQTSAVTCLQW

IFT172

106

Q9UG01
WLTTQVLATCNTESF

FADS2B

396

A8MWK0
LVRSLQTFSQAWFTC

PRG2

111

P13727
VAFCFWLLSNVLLST

DUOXA2

186

Q1HG44
ISFNAQTTLKNFCQW

ADAMTS9

356

Q9P2N4
WTQTCNTLFFIFSTI

CERS3

256

Q8IU89
AVQALWKQFQSFCCS

IL32

186

P24001
WKQFQSFCCSLSELF

IL32

191

P24001
ESLRLFDSICNNNWF

GNAZ

246

P19086
FDSICNNNWFINTSL

GNAZ

251

P19086
WSISSCDAFLNVFQS

DIP2C

626

Q9Y2E4
LFLQWQETRCANASF

B3GNT3

191

Q9Y2A9
QNVCFWTKTRASFSF

HASPIN

376

Q8TF76
INANAVAWRCFTFSK

CEP192

1536

Q8TEP8
TNNQLFFLGFAQVWC

ECE1

701

P42892
WSISSCDAFLNVFQS

DIP2A

641

Q14689
SFLTTWLAISNSFCN

GPR21

286

Q99679
AAFILAISQAQSWCL

FADS3

166

Q9Y5Q0
WRTQAVVLAQCNFSL

SLC22A13

221

Q9Y226
ITCALLQLFTWSQFT

MFSD13A

476

Q14CX5
SALVNASVAFECWIN

PKD1L1

601

Q8TDX9
QNNLQELWSLFDFAC

ERCC6L

261

Q2NKX8
SLHLAWLLSQACFNF

NYNRIN

376

Q9P2P1
QISSDNCFLQWGFKT

MTERF3

46

Q96E29
CFLEAIWSNIFSLNL

PLA2G4D

521

Q86XP0
DLFNAAFVSCWSELN

MTOR

1316

P42345
LFSTVTPCQQNFFWD

RUNX2

6

Q13950
FASCWNSQEFIQTLS

TEX14

1241

Q8IWB6
NTILSCFKDNSIFAW

TBC1D31

181

Q96DN5
CTLQFESAWVLTNIA

KPNA1

141

P52294
STNKCSANFWFNPLS

SORCS2

721

Q96PQ0
DSNQFCWRNLFSCIN

STRIP1

656

Q5VSL9
AFNWLLCNVIQTTSL

MYCBP2

3576

O75592
LDTNSWIFACINSTS

PGAP1

391

Q75T13
TWCIFNSSVQQDHLS

SPATA31C1

301

P0DKV0
ANSSCVRNAFWLQIT

RIG

46

Q13278
PLWANSLQFVFACIS

SLC6A20

6

Q9NP91
ALQSSFTCWNGTVLQ

ALK

436

Q9UM73
ETKCVFWNFRLANNT

ADGRF5

951

Q8IZF2
ISLLNCSNATLWLSF

SLC49A3

36

Q6UXD7
FVSQSNCQQFLNTVW

TRPC1

321

P48995
RQWNNCAFLESSAKS

nan

136

A6NIZ1
LGVFCFSQENIIWSN

THBS4

921

P35443
WQFLFSTTKDCCLFQ

VWDE

116

Q8N2E2
SWLQNLPSSVFSCAF

WDR47

246

O94967
FANNSSLWFTSCLSI

TAS2R9

91

Q9NYW1
LCSAQVAAWFFATLA

TMEM102

261

Q8N9M5
NTCWFSAVIQSLFNL

USP25

176

Q9UHP3
TWSTCAFTIQAIENL

UBR1

1321

Q8IWV7
NVFTMQWFLTLFATC

TBC1D30

426

Q9Y2I9
QWFLTLFATCLPNQT

TBC1D30

431

Q9Y2I9
SCWDQSFLTNITFLK

SAYSD1

91

Q9NPB0
IWNIATNKLTFLNSF

ATP6V0A1

521

Q93050
AINFSCWSAVKLQLS

XKR3

316

Q5GH77
NNVAAFTSNWVCQTL

TMEM204

21

Q9BSN7
NLTLFECWSSSSNQN

PHF8

311

Q9UPP1
SDFLLLLCASQQWQV

PIEZO1

1101

Q92508
LFCNSQLSNDIWLNV

TEX15

456

Q9BXT5
NASSWVFSRCNSNFV

MID2

621

Q9UJV3
GASNIINNFIICWSF

TMEM217

51

Q8N7C4
GSFELWQVQCAQSFQ

TRIM65

366

Q6PJ69
CQLEQSSFLNPSFQW

TTLL4

356

Q14679
AFALWLQDSTQTLQC

VIRMA

756

Q69YN4
LRCNFSDSVNNLQWF

TRAV22

41

A0A0B4J277
CQVCGQSFTQSWFLK

ZNF219

276

Q9P2Y4