Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein localization to chromosome, telomeric region

CCT8 TNKS TNKS2

3.22e-0532403GO:0070198
GeneOntologyBiologicalProcesspositive regulation of telomere maintenance via telomerase

CCT8 TNKS TNKS2

4.61e-0536403GO:0032212
GeneOntologyBiologicalProcesspositive regulation of telomere maintenance via telomere lengthening

CCT8 TNKS TNKS2

5.88e-0539403GO:1904358
GeneOntologyBiologicalProcesscellular response to granulocyte macrophage colony-stimulating factor stimulus

CSF2 PRLR

1.63e-0410402GO:0097011
GeneOntologyBiologicalProcessresponse to granulocyte macrophage colony-stimulating factor

CSF2 PRLR

1.99e-0411402GO:0097012
GeneOntologyBiologicalProcessprotein poly-ADP-ribosylation

TNKS TNKS2

1.99e-0411402GO:0070212
GeneOntologyBiologicalProcessprotein auto-ADP-ribosylation

TNKS TNKS2

1.99e-0411402GO:0070213
GeneOntologyBiologicalProcessregulation of telomere maintenance via telomerase

CCT8 TNKS TNKS2

2.14e-0460403GO:0032210
GeneOntologyBiologicalProcessregulation of telomere maintenance via telomere lengthening

CCT8 TNKS TNKS2

3.24e-0469403GO:1904356
GeneOntologyBiologicalProcesspositive regulation of telomere maintenance

CCT8 TNKS TNKS2

3.67e-0472403GO:0032206
HumanPhenoAbsent sperm flagella

CFAP251 QRICH2 DNAH17 CFAP65

4.10e-0628214HP:0032558
HumanPhenoCoiled sperm flagella

CFAP251 QRICH2 DNAH17 CFAP65

7.13e-0632214HP:0032560
HumanPhenoShort sperm flagella

CFAP251 QRICH2 DNAH17 CFAP65

8.09e-0633214HP:0032559
HumanPhenoAbnormal sperm tail morphology

CFAP251 QRICH2 DNAH17 CFAP65

2.37e-0543214HP:0012868
HumanPhenoAbnormal sperm morphology

CFAP251 QRICH2 DNAH17 CFAP65

1.30e-0466214HP:0012864
HumanPhenoAbnormal germ cell morphology

CFAP251 QRICH2 DNAH17 CFAP65

1.38e-0467214HP:0012862
HumanPhenoAbnormal male germ cell morphology

CFAP251 QRICH2 DNAH17 CFAP65

1.38e-0467214HP:0012863
MousePhenoabnormal pancreas morphology

TNK1 OGT CSF2 ATXN2 ONECUT1 PRLR GNPTAB

1.24e-05367317MP:0001944
MousePhenoabnormal pancreatic islet morphology

TNK1 CSF2 ATXN2 ONECUT1 PRLR

5.61e-05190315MP:0005215
MousePhenoabnormal endocrine pancreas morphology

TNK1 CSF2 ATXN2 ONECUT1 PRLR

5.75e-05191315MP:0009165
DomainAnk_3

TNKS ANK3

1.89e-0410392PF13606
DomainPoly(ADP-ribose)pol_cat_dom

TNKS TNKS2

5.66e-0417392IPR012317
DomainPARP_CATALYTIC

TNKS TNKS2

5.66e-0417392PS51059
DomainPARP

TNKS TNKS2

5.66e-0417392PF00644
Domain-

TNKS TNKS2

5.66e-04173923.90.228.10
DomainWGR_domain

TNKS TNKS2

1.14e-0324392IPR008893
DomainSAM_2

TNKS TNKS2

3.63e-0343392PF07647
DomainAnk_2

TNKS TNKS2 ANK3

1.01e-02215393PF12796
DomainAnk

TNKS TNKS2 ANK3

1.19e-02228393PF00023
Pubmed

Tankyrase is necessary for canonical Wnt signaling during kidney development.

TNKS TNKS2

1.36e-06241220549720
Pubmed

Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.

TNKS TNKS2

1.36e-06241218612384
Pubmed

Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy.

TNKS TNKS2

1.36e-06241228723574
Pubmed

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.

TNKS TNKS2

1.36e-06241227494558
Pubmed

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.

TNKS TNKS2

1.36e-06241218026951
Pubmed

Structural insights into SAM domain-mediated tankyrase oligomerization.

TNKS TNKS2

1.36e-06241227328430
Pubmed

Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.

TNKS TNKS2

1.36e-06241224116873
Pubmed

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1.

TNKS TNKS2

1.36e-06241215795250
Pubmed

Regulation of tankyrase activity by a catalytic domain dimer interface.

TNKS TNKS2

1.36e-06241230055800
Pubmed

Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.

TNKS TNKS2

1.36e-06241229263426
Pubmed

Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.

TNKS TNKS2

1.36e-06241224291818
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CCT8 GRIA1 TNKS OGT FRMPD3 ANK3 ATXN2 IQSEC2 ZNF516

1.46e-0696341928671696
Pubmed

Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation.

TNKS TNKS2

4.06e-06341232442396
Pubmed

Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.

TNKS TNKS2

4.06e-06341226246473
Pubmed

Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells.

FOXO1 OGT

4.06e-06341224730386
Pubmed

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

TNKS TNKS2

4.06e-06341233361107
Pubmed

Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.

TNKS TNKS2

4.06e-06341211739745
Pubmed

Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.

TNKS TNKS2

4.06e-06341225939383
Pubmed

Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.

TNKS TNKS2

4.06e-06341227441654
Pubmed

Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.

TNKS TNKS2

4.06e-06341233923443
Pubmed

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.

TNKS TNKS2

4.06e-06341211454873
Pubmed

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.

TNKS TNKS2

4.06e-06341221251231
Pubmed

PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.

TNKS TNKS2

8.12e-06441238272024
Pubmed

The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182).

TNKS TNKS2

8.12e-06441211854288
Pubmed

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.

TNKS TNKS2

8.12e-06441230260955
Pubmed

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.

TNKS TNKS2

8.12e-06441226513298
Pubmed

Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression.

TNKS TNKS2

8.12e-06441236383218
Pubmed

Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14.

TNKS TNKS2

8.12e-06441211278563
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

CCT8 TNKS OGT TNKS2 RPL13

1.25e-0525641532698014
Pubmed

Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase).

TNKS TNKS2

1.35e-05541211802774
Pubmed

Tankyrase represses autoinflammation through the attenuation of TLR2 signaling.

TNKS TNKS2

1.35e-05541235362478
Pubmed

The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation.

TNKS TNKS2

1.35e-05541222473005
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TNKS ADAMTS8 OGT TNKS2 ANK3 DROSHA GNPTAB IQSEC2 RPL13

1.50e-05128541935914814
Pubmed

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

TNKS TNKS2

2.03e-05641219759537
Pubmed

Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.

TNKS TNKS2

2.03e-05641221799911
Pubmed

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.

TNKS TNKS2

2.03e-05641226845027
Pubmed

Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles.

TNKS TNKS2

2.03e-05641210988299
Pubmed

Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.

TNKS TNKS2

2.03e-05641234128958
Pubmed

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

FOXO1 UGT3A2 RRM1 DROSHA

2.27e-0514041420819778
Pubmed

Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.

TNKS TNKS2

2.84e-05741222153076
Pubmed

Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.

TNKS TNKS2

2.84e-05741225547115
Pubmed

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.

TNKS TNKS2

2.84e-05741221478859
Pubmed

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.

TNKS TNKS2

2.84e-05741231554794
Pubmed

AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein.

GRIA1 ANK3

3.78e-05841228821923
Pubmed

Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner.

TNKS TNKS2

4.86e-05941212080061
Pubmed

Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis.

TNKS TNKS2

4.86e-05941219766477
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

FOXO1 BAZ1B OGT DROSHA DHX38 ZNF516

6.19e-0558841638580884
Pubmed

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

BAZ1B ATXN2 QRICH2

6.91e-056741323263486
Pubmed

Genetic mapping and evaluation of candidate genes for spasmodic, a neurological mouse mutation with abnormal startle response.

GRIA1 CSF2

7.41e-05114128406478
Pubmed

Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.

TNKS TNKS2

7.41e-051141220937264
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

CCT8 TNKS TNKS2 RPL13 ZNF516

1.02e-0439841535016035
Pubmed

Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.

TNKS TNKS2

1.22e-041441235733260
Pubmed

High-throughput RNAi screening reveals novel regulators of telomerase.

TNKS TNKS2

1.61e-041641221531765
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

TNKS TNKS2

1.61e-041641225043379
Pubmed

USP25 regulates Wnt signaling by controlling the stability of tankyrases.

TNKS TNKS2

1.61e-041641228619731
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

CCT8 CELF1 ATXN2 DROSHA DHX38 RPL13

1.79e-0471441628302793
Pubmed

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment.

FOXO1 PRLR

2.29e-041941229911998
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

ZMIZ1 ANK3

2.29e-041941218711365
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CCT8 OGT MED17 RRM1 CELF1 ATXN2 ZNF516

2.77e-04110341734189442
Pubmed

Genetic mapping of 21 genes on mouse chromosome 11 reveals disruptions in linkage conservation with human chromosome 5.

GRIA1 CSF2

2.81e-04214129070927
Pubmed

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

TNKS TNKS2

3.09e-042241227521426
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CCT8 BAZ1B OGT MED17 ANK3

4.51e-0454941538280479
Pubmed

Embryonic Steroids Control Developmental Programming of Energy Balance.

FOXO1 ONECUT1

4.67e-042741234599818
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

BAZ1B TNKS ATXN2 ONECUT1 IQSEC2 RPL13 ZNF646

4.67e-04120341729180619
Pubmed

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function.

FOXO1 ONECUT1

5.39e-042941225784544
Pubmed

Maternal diabetes alters transcriptional programs in the developing embryo.

BAZ1B OGT

6.58e-043241219538749
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

OGT PRLR ZNF516

6.87e-0414641329688375
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CCT8 RRM1 ANK3 ONECUT1 PRLR GNPTAB TMEM126B

7.17e-04129341715342556
Pubmed

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.

CFAP251 ATXN2

7.43e-043441224026423
Pubmed

Interaction network of human early embryonic transcription factors.

BAZ1B OGT ZMIZ1 ZNF516

7.69e-0435141438297188
Pubmed

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.

ATXN2 DROSHA RPL13

8.17e-0415541333838681
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

CCT8 OGT DHX38 RPL13

8.19e-0435741437059091
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

TNK1 MED17 ONECUT1 ZNF516

8.54e-0436141418976975
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

CFAP251 ANK3 NXPE4 RPL13

8.54e-0436141426167880
Pubmed

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age.

FOXO1 PRLR

1.03e-034041236843585
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

CCT8 OGT CELF1 ATXN2 RPL13

1.16e-0367841530209976
CytobandEnsembl 112 genes in cytogenetic band chr5p13

UGT3A2 DROSHA PRLR

2.66e-04139413chr5p13
Cytoband5p13.2

UGT3A2 PRLR

3.56e-04314125p13.2
CytobandEnsembl 112 genes in cytogenetic band chr12q24

CFAP251 ATXN2 TMEM116 ZNF891

5.12e-04415414chr12q24
Cytoband5q31.1

GRIA1 CSF2

1.47e-03634125q31.1
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

TNKS TNKS2

2.88e-0417272684
GeneFamilyAnkyrin repeat domain containing

TNKS TNKS2 ANK3

5.46e-03242273403
GeneFamilySterile alpha motif domain containing

TNKS TNKS2

7.60e-0388272760
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000

BAZ1B TNKS OGT ZMIZ1 TNKS2 ANK3 CELF1 ZNF646

1.25e-07312418gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

BAZ1B TNKS OGT ZMIZ1 TNKS2 RRM1 ANK3 ZNF646

6.15e-07385418gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500

BAZ1B TNKS ZMIZ1 TNKS2 ANK3

9.72e-06149415gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

BAZ1B GRIA1 TNKS OGT ZMIZ1 TNKS2 RRM1 ANK3 ZNF646

2.07e-05818419gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000

BAZ1B TNKS ZMIZ1 TNKS2

4.27e-05101414gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500

BAZ1B ZMIZ1 TNKS2 RRM1 ANK3

4.95e-05209415gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000

BAZ1B TNKS OGT ZMIZ1 TNKS2

4.95e-05209415gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500

VPS41 OGT TNKS2 ANK3

7.57e-05117414gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

BAZ1B TNKS OGT ZMIZ1 TNKS2 ANK3 CELF1 ZNF646

1.31e-04806418gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500

BAZ1B GRIA1 ZMIZ1 TNKS2 RRM1 ANK3

1.37e-04416416gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

BAZ1B OGT ZMIZ1 TNKS2 ANK3

1.41e-04261415gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000

TNKS ZMIZ1 TNKS2 ANK3

1.78e-04146414gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_500

BAZ1B TNKS TNKS2

1.92e-0458413gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500

BAZ1B OGT TNKS2 ANK3

2.30e-04156414gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

BAZ1B OGT ZMIZ1 TNKS2 CELF1

4.16e-04330415DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_500

ZMIZ1 TNKS2 ANK3

4.60e-0478413gudmap_developingKidney_e15.5_Cap mesenchyme_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500

BAZ1B TNKS2 ANK3 CELF1

5.25e-04194414DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500

BAZ1B ZMIZ1 TNKS2

6.76e-0489413gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

BAZ1B TNKS TNKS2 ANK3 CELF1

6.91e-04369415DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000

VPS41 TNK1 BAZ1B OGT ZMIZ1 TNKS2 ANK3

6.94e-04786417gudmap_developingKidney_e15.5_Medullary collecting duct_1000
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_1000

BAZ1B ZMIZ1 TNKS2

7.21e-0491413DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

BAZ1B TNKS OGT ZMIZ1 TNKS2 ANK3 TMEM116

7.43e-04795417gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

BAZ1B OGT ZMIZ1 TNKS2 ANK3

7.43e-04375415gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

BAZ1B OGT ZMIZ1 TNKS2 ANK3

7.80e-04379415gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000

BAZ1B OGT ZMIZ1 TNKS2

9.29e-04226414gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

BAZ1B OGT TNKS2 RRM1 CELF1

9.60e-04397415gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500

BAZ1B TNKS ZMIZ1 TNKS2 ANK3

1.07e-03407415gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

FOXO1 GRIA1 ADAMTS8 ANK3

1.59e-051654146ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

FOXO1 GRIA1 ADAMTS8 ANK3

1.91e-051734146fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

FOXO1 GRIA1 ADAMTS8 ANK3

2.24e-051804145842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FOXO1 OGT RPL13 RIC3

3.18e-05197414836dd8110d5689f944ad1d301def38c32278b5b5
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

FOXO1 ANK3 RPL13 RIC3

3.18e-05197414ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CSF2 NXPE4 CFAP65

3.69e-05704136b706d0b6b7565ba7d6b169c6b49497e510de68b
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CSF2 NXPE4 CFAP65

3.69e-05704138e1c2442e89ed54603905472daa11ec23238ffb0
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ALPK2 RPL13 CFAP65

1.70e-04117413f3c77b234e461566aac81ede0ef84008c9a9f51e
ToppCellIIH-CD4-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

ANK3 RPL13 RIC3

2.76e-04138413e474a0785a651020156baacbf89c4d2b1e4cc473
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CFAP251 FRMPD3 IQSEC2

3.26e-041464131bf67a9416f52198931b912a31be4bab09fefd19
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Lung / Manually curated celltypes from each tissue

TMEM116 DROSHA RIC3

3.60e-041514139bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

ANK3 TMEM116 IQSEC2

3.88e-041554139cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM126B ZNF516 ZNF646

4.26e-04160413913e59cecf3b1bdd1ef32b4e320042b9bbdb54bc
ToppCellHealthy/Control-CD8+_T_naive|Healthy/Control / Disease group and Cell class

TNK1 RPL13 RIC3

4.26e-04160413e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

FOXO1 ZMIZ1 ZNF646

4.34e-04161413fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM116 PRLR ALPK2

4.58e-04164413cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM116 PRLR ALPK2

4.58e-041644135dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM116 PRLR ALPK2

4.58e-04164413f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OGT ANK3 TMEM116

4.83e-04167413ced6ed9b412739c6ced622523347c10295edbf53
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

FRMPD3 ALPK2 RIC3

4.83e-04167413cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellControl-NK|Control / Disease group and Cell class

CSF2 IQSEC2 ZNF516

4.91e-04168413683d389c8a1e791bfc773e63148115a21a6566db
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 QRICH2 CFAP65

4.91e-04168413100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZMIZ1 RPL13 ZNF516

5.00e-04169413a0681317867e31319210a23e56660a53f4529efe
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

FOXO1 ADAMTS8 ANK3

5.00e-04169413a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UGT3A2 ADAMTS8 PRLR

5.00e-04169413f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RRM1 ANK3 TMEM116

5.08e-041704134ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCellInt-URO-Lymphocyte-T_NK-CD4_Naive|Int-URO / Disease, Lineage and Cell Type

ANK3 RPL13 RIC3

5.08e-04170413577915dd1f5c418b9b98a7a7153e2b5d1b93ca84
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

TNK1 ANK3 RIC3

5.26e-0417241347865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZMIZ1 RPL13 ZNF516

5.26e-04172413ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZMIZ1 RPL13 ZNF516

5.26e-041724133fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

CSF2 ANK3 TMEM116

5.35e-04173413f6e36ea98a9c669ff393d141455aaecef083f738
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 PRLR CFAP65

5.35e-04173413a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 TMEM116 PRLR

5.44e-041744135f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMIZ1 NXPE4 IQSEC2

5.44e-0417441355cc8300489d11322724159ec7d0e1d32a702e91
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VPS41 CFAP251 ALPK2

5.53e-04175413284fdc7a9d303636a637041846850d19d114861a
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HINT3 ANK3 ATXN2

5.53e-04175413bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 QRICH2 CFAP65

5.53e-041754138902c38067f025b094ca9c28c449c32a66eded1c
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 QRICH2 CFAP65

5.53e-041754136bb8fc2959583644f16b22e906af91af62a3a633
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 TMEM116 PRLR

5.53e-0417541377c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE4 ALPK2 DNAH17

5.72e-0417741314fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B TNKS NUP210L

5.81e-0417841301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRIA1 PIGO RIC3

6.00e-04180413e9785ac2806103f725f5a5208495826354ec6e22
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

FOXO1 ADAMTS8 ANK3

6.10e-041814137d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 TMEM116 PRLR

6.10e-0418141330729f0364f719c044712a51453e22dc2c1a232b
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Tfh|bone_marrow / Manually curated celltypes from each tissue

FOXO1 ANK3 RIC3

6.20e-04182413c059e79da49db3649052581d95255f03e2956144
ToppCellURO-Lymphocyte-T_NK-dnT|URO / Disease, Lineage and Cell Type

FOXO1 TNKS PIGO

6.20e-04182413f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 TMEM116 PRLR

6.40e-041844139365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 TMEM116 PRLR

6.40e-04184413204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellCOVID-CD4-naive_CD4|COVID / Condition, Cell_class and T cell subcluster

ANK3 RPL13 RIC3

6.40e-0418441300db55970d336a301035efe43a4ab4db62627f38
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 TMEM116 PRLR

6.40e-041844137cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 TMEM116 PRLR

6.40e-0418441353b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellfacs-Trachea-nan-24m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2 TMEM116 PRLR

6.50e-04185413e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCellControl-B_memory-0|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 RPL13 RIC3

6.60e-0418641380f6f25dbe3c5efe4bc350f5d2eb990c38aab338
ToppCellEpithelial-C_(AT2)|World / shred on cell class and cell subclass (v4)

CSF2 ANK3 TMEM116

6.60e-04186413b7b1763fc52b4485d843a4a6727055e6c95ebad3
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAMTS8 ZNF891 RIC3

6.60e-04186413cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS8 ANK3 RPL13

6.71e-0418741369b47f00598d647e2a99427ebddf42c339428e47
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 ANK3 PRLR

6.92e-04189413a48df46274d51e84ffb40264646de7346104efb9
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

FOXO1 OGT ANK3

7.02e-04190413d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 ANK3 CFAP65

7.02e-041904132fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.13e-0419141355a282478488efd1561ea57a6f0218f55f711bb0
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FOXO1 ZMIZ1 GNPTAB

7.13e-0419141340813c397f533c2f4a6359a77757f736b6d9e07d
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ANK3 TMEM116 RPL13

7.13e-0419141325dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.24e-04192413ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCell3'-Child09-12-SmallIntestine-Neuronal|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.24e-0419241324f40dadec04f4f99c31000fa9f09d07148fa190
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

FOXO1 OGT ANK3

7.24e-04192413eb4909574fb5fc91399463523e2737095773200a
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

FOXO1 OGT ANK3

7.24e-04192413b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.24e-0419241371e04e197825856c6d4278fc76c58ab17ffa2387
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 RPL13 RIC3

7.24e-0419241378546a6e077076834fd717607610ab6df3b6e7ba
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FOXO1 ONECUT1 PRLR

7.24e-04192413e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FOXO1 GRIA1 ADAMTS8

7.24e-0419241362904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

ANK3 RPL13 RIC3

7.35e-04193413beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCellmild_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.35e-0419341342ddacc55658ea6ba4248ac19c9c3709f342b4f5
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK3 RPL13 RIC3

7.35e-04193413f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK3 RPL13 RIC3

7.35e-041934132901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCellmild_COVID-19-CD4+_T_naive|mild_COVID-19 / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.35e-0419341340fc4a519c883c6c269a9c05be36ae906f75426a
ToppCellILEUM-inflamed-(1)_T_cell-(1)_TFH-like|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FOXO1 RPL13 RIC3

7.35e-0419341388cc740dd216ea80605b857c27914a8bc6ba6771
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 ANK3 CFAP65

7.35e-04193413ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANK3 RPL13 RIC3

7.35e-04193413f8af695457d2a0a911a5ac491742465864ebda37
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANK3 RPL13 RIC3

7.35e-04193413089aece40130034a89a5213be778f10b0787eeba
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

ANK3 RPL13 RIC3

7.35e-04193413f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

ANK3 RPL13 RIC3

7.35e-041934136218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOXO1 GRIA1 ADAMTS8

7.35e-04193413b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ANK3 TMEM116 RPL13

7.35e-04193413725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 RPL13 RIC3

7.35e-04193413192432ce2f8f95f8b8fa3812d311d35ee2b89f86
ToppCellHealthy_donor-CD4+_T_naive|World / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.46e-04194413bcaaa6b6ce5b3552f11311d8ee91c35b8ec065f8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANK3 RPL13 RIC3

7.46e-041944132e2019a7bf57f257f0ff9b24eacff59dbb952ebb
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOXO1 GRIA1 ADAMTS8

7.46e-04194413e93de9428c986b8943fc169258847c650cfab0e5
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK3 RPL13 RIC3

7.46e-04194413e27b5be246ff9fb72180f471926b7d7e8b8cf357
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NXPE4 ALPK2 DNAH17

7.46e-041944138ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellHealthy_donor-CD4+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.46e-04194413a8a0368a4e0eb5654fdffc8a779b08ad402aa2eb
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK3 RPL13 RIC3

7.46e-04194413e0ccf18edbae09fc1068f1e923f1bc0d0ff44195
ToppCellHealthy/Control-CD4+_Tcm|World / Disease group and Cell class

ANK3 RPL13 RIC3

7.46e-04194413cbdd1786305108cbeddea07a21120067d78c59a0
ToppCellmild_COVID-19-CD4+_Tcm|mild_COVID-19 / disease group, cell group and cell class (v2)

ANK3 RPL13 RIC3

7.46e-04194413cf085813138a73878f9586059cd1d01d1a7ee748
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK3 RPL13 RIC3

7.46e-04194413fc0504730ae576ff46ba0bc9f585c53ab78d914c
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANK3 RPL13 RIC3

7.46e-04194413d788d5bd1e651706e7e2d54ada546a5e84f86ff0
ToppCellControl-Lymphoid_T/NK-CD4+_T_naive|Control / Disease group, lineage and cell class

ANK3 RPL13 RIC3

7.46e-04194413aabcd9f71d8ef54add5c46d8a3e226e3ae3ab124
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.46e-04194413d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.46e-04194413bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA1 ADAMTS8 ANK3

7.46e-04194413408dfc7060095972a54ae37ae8105521df6fbbee
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 RPL13 RIC3

7.57e-04195413497d4bfbc38bcafab37e8a9c20bc9141f2e78d2a
DiseaseC-reactive protein measurement

BAZ1B GRIA1 TNKS CFAP251 ZMIZ1 ANK3 CELF1 ONECUT1 NUP210L DNAH17

3.47e-0612064010EFO_0004458
Diseasealkaline phosphatase measurement

BAZ1B TNKS ZMIZ1 TNKS2 ATXN2 ONECUT1 ALPK2 DHX38

5.51e-051015408EFO_0004533
DiseaseC-C motif chemokine 3 measurement

GRIA1 ATXN2

2.70e-0418402EFO_0008051
Diseasecorneal hysteresis

FOXO1 ADAMTS8

3.35e-0420402EFO_0010066
Diseaseintraocular pressure measurement

FOXO1 ADAMTS8 ATXN2 ZNF891 ZNF516

5.99e-04509405EFO_0004695
Diseaseeye measurement

FOXO1 ATXN2

6.16e-0427402EFO_0004731
DiseaseIniencephaly

CSF2 RRM1

6.62e-0428402C0152234
DiseaseTethered Cord Syndrome

CSF2 RRM1

6.62e-0428402C0080218
DiseaseSpinal Cord Myelodysplasia

CSF2 RRM1

6.62e-0428402C0344479
DiseaseExencephaly

CSF2 RRM1

6.62e-0428402C0266453
DiseaseNeurenteric Cyst

CSF2 RRM1

6.62e-0428402C0027806
DiseaseAcrania

CSF2 RRM1

6.62e-0428402C0702169
DiseaseDiastematomyelia

CSF2 RRM1

6.62e-0428402C0011999
DiseaseCraniorachischisis

CSF2 RRM1

7.11e-0429402C0152426
Diseasepappalysin‐1 measurement

CELF1 ATXN2

7.11e-0429402EFO_0010618
DiseaseNeural Tube Defects

CSF2 RRM1

7.61e-0430402C0027794
Diseasecarbohydrate intake measurement

ATXN2 TMEM116

9.78e-0434402EFO_0010811
Diseasewaist-hip ratio

ZMIZ1 ANK3 CELF1 ATXN2 ONECUT1 DNAH17 CFAP65

1.18e-031226407EFO_0004343
Diseasetestosterone measurement

BAZ1B ZMIZ1 TNKS2 ANK3 ONECUT1 PRLR IQSEC2

1.48e-031275407EFO_0004908
Diseaseneutrophil count

FOXO1 ZMIZ1 TNKS2 ATXN2 NUP210L IQSEC2 ZNF516

2.34e-031382407EFO_0004833

Protein segments in the cluster

PeptideGeneStartEntry
STVMHGLMPVFKPGH

ALPK2

1936

Q86TB3
PGMHHPIQMKPADSE

CELF1

86

Q92879
RLFGPMGKHHVMAPL

ADAMTS8

381

Q9UP79
KMMSPNKLHTNFHIP

BAZ1B

371

Q9UIG0
NHKPPFGNTMSGIHK

CFAP251

1036

Q8TBY9
SMSMAPHKAHTLAPG

QRICH2

1191

Q9H0J4
FGFTSRKVPAHMPHM

GNPTAB

946

Q3T906
NPHMMGDTAPFHNIS

CFAP65

1406

Q6ZU64
HHQSAMMHPASAAGP

ATXN2

1011

Q99700
MGFHMPPFCSISHLH

HINT3

131

Q9NQE9
KHFIFSHHPQMMPAA

IQSEC2

1386

Q5JU85
KMLTPNGFEAHHPAM

ONECUT1

211

Q9UBC0
EFHKQTLSSIMMPHP

MED17

381

Q9NVC6
MMPHPASAPFGHKRM

MED17

391

Q9NVC6
EGKLGRFPPMMHHHQ

RIC3

41

Q7Z5B4
RFPPMMHHHQAPSDG

RIC3

46

Q7Z5B4
MGRKEHESPSQPHMC

GUCA1ANB

1

X6R8D5
MMASHYKQHCPPTPE

CSF2

96

P04141
ASHNKMMNPSSHTHP

FOXO1

511

Q12778
FQHEPHPRTGTMMLK

DNAH17

1426

Q9UFH2
LPPPMIKADYMHSAH

FRMPD3

506

Q5JV73
MASSLSSPVKQMPGH

ANK3

1696

Q12955
HDFPKSMQSIPCMSH

GRIA1

881

P42261
MAPSRNGMVLKPHFH

RPL13

1

P26373
MLTPKFLAFPHHPMG

NUP210L

466

Q5VU65
SHLMQSIPGMHNPDK

OGT

571

O15294
AMTHPSHHLNFGMNP

DROSHA

896

Q9NRR4
PKVFKMAASMHGQPS

TMEM126B

26

Q8IUX1
PQHMPCAALTHMYSK

NXPE4

246

Q6UWF7
QHRFSMDLKMPAFHP

ZNF516

666

Q92618
NPHNGKHSPMVAKST

RRM1

106

P23921
LQFSTMKMAHAPPGH

TNKS

1261

O95271
MKMAHAPPGHHSVIG

TNKS

1266

O95271
MSVHSKEHPSQGMKP

PRLR

326

P16471
NPMALKSHMRTHAPE

ZNF646

86

O15015
SHKCILMHSPPSAMA

TMEM116

56

Q8NCL8
NSMMFGHLSPMRIPH

nan

36

A8MX80
GMPCHLHPTSSLFGM

DHX38

1096

Q92620
HMFHKECLPMPSMNS

VPS41

816

P49754
SAMKMAHSPPGHHSV

TNKS2

1111

Q9H2K2
KGLHPLQPCHPHYMM

nan

376

Q3C1V9
NSMMFGHLSPVRIPH

nan

36

A8MUI8
HNHPMGMPGARKAAA

TNK1

566

Q13470
HGPHHPEMAKKLSQM

PIGO

241

Q8TEQ8
HNVTMLNHKRGPFMP

UGT3A2

51

Q3SY77
MALHVPKAPGFAQML

CCT8

1

P50990
KHGMHFTHNMFPVPN

ZNF891

271

A8MT65
KPLSHPMQETMPHAG

ZMIZ1

936

Q9ULJ6