Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

MAML1 MED12L BCL9L KMT2C NCOA6 ARID1B MAML3

4.80e-08303247GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

MAML1 MED12L BCL9L KMT2C NCOA6 ARID1B MAML3

3.08e-06562247GO:0003712
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MAML1 MED12L BCL9L KMT2C NCOA6 ARID1B MAML3

3.17e-041160247GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

MAML1 MED12L BCL9L KMT2C NCOA6 ARID1B MAML3

8.13e-041356247GO:0060090
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

MAML1 MAML3

2.72e-057242GO:0007221
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MAML1 MED12L BCL9L KMT2C NCOA6 EYA1 MAML3 CREB5

1.16e-041390248GO:0045944
GeneOntologyBiologicalProcessregulation of immature T cell proliferation in thymus

TMEM131L BMI1

1.75e-0417242GO:0033084
GeneOntologyBiologicalProcessregulation of immature T cell proliferation

TMEM131L BMI1

1.96e-0418242GO:0033083
GeneOntologyBiologicalProcessimmature T cell proliferation in thymus

TMEM131L BMI1

2.19e-0419242GO:0033080
GeneOntologyBiologicalProcessimmature T cell proliferation

TMEM131L BMI1

2.43e-0420242GO:0033079
GeneOntologyCellularComponentMLL3/4 complex

KMT2C NCOA6

8.28e-0512242GO:0044666
GeneOntologyCellularComponentnuclear protein-containing complex

MED12L CSTF2 BMI1 BCL9L KMT2C NCOA6 ARID1B INIP

9.85e-051377248GO:0140513
DomainNeuroggenic_mastermind-like_N

MAML1 MAML3

4.74e-063242IPR019082
DomainMamL-1

MAML1 MAML3

4.74e-063242SM01275
DomainMamL-1

MAML1 MAML3

4.74e-063242PF09596
PathwayWP_KLEEFSTRA_SYNDROME

KMT2C NCOA6 ARID1B

5.22e-0629173M48076
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML1 MAML3

6.12e-0510172MM15535
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML1 MAML3

8.97e-0512172M27159
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

MAML1 MAML3

8.97e-0512172M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

MAML1 MAML3

8.97e-0512172M47533
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

MAML1 MAML3

1.06e-0413172M47534
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

MAML1 CHD9 KMT2C NCOA6 ARID1B EYA1 TIAM1 MAML3

1.17e-041432178M509
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML1 MAML3

1.24e-0414172M27808
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

MAML1 MAML3

1.63e-0416172M27121
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML1 MAML3

2.07e-0418172MM14775
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CHD9 NCOA6

2.07e-0418172M26942
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML1 MAML3

2.57e-0420172M27881
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

MAML1 MAML3

3.41e-0423172MM14954
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML1 MAML3

4.04e-0425172M27880
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

MAML1 MAML3

4.72e-0427172M39545
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

CHD9 NCOA6

4.72e-0427172M26943
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

MAML1 MAML3

5.08e-0428172M6177
PathwayREACTOME_SIGNALING_BY_NOTCH2

MAML1 MAML3

7.07e-0433172M604
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

BMI1 ARID1B

8.89e-0437172M27797
PathwayPID_RAC1_REG_PATHWAY

ARHGAP17 TIAM1

9.38e-0438172M241
PathwayREACTOME_SIGNALING_BY_NOTCH

MAML1 MAML3

9.88e-0439172MM14604
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

CHD9 NCOA6

1.15e-0342172M27172
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

MAML1 MAML3

1.15e-0342172M17541
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

KMT2C NCOA6

1.15e-0342172M48018
PathwayWP_NOTCH_SIGNALING_WP268

MAML1 MAML3

1.31e-0345172M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

MAML1 MAML3

1.37e-0346172MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

MAML1 MAML3

1.43e-0347172M7946
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML1 MAML3

1.49e-0348172M611
PathwayREACTOME_HEME_SIGNALING

CHD9 NCOA6

1.56e-0349172M41832
PathwayREACTOME_SIGNALING_BY_NOTCH3

MAML1 MAML3

1.56e-0349172M618
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

CHD9 NCOA6

1.96e-0355172M27145
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

CHD9 NCOA6

1.96e-0355172M27001
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

MAML1 MAML3

2.17e-0358172M29616
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

CHD9 NCOA6

2.33e-0360172M41830
PathwayWP_NOTCH_SIGNALING_WP61

MAML1 MAML3

2.40e-0361172M39540
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

BMI1 KMT2C ARID1B

2.68e-03237173M27786
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

KMT2C MAML3

2.72e-0365172M39682
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

MAML1 MAML3

3.06e-0369172M46439
PathwayREACTOME_CIRCADIAN_CLOCK

CHD9 NCOA6

3.15e-0370172M938
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

KMT2C NCOA6 ARID1B

3.26e-03254173M27131
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML1 MAML3

3.51e-0374172M616
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

MAML1 CSMD3

3.51e-0374172M39857
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML1 MAML3

3.70e-0376172MM15520
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

MAML1 CSTF2 BMI1 KMT2C ARID1B MAML3

4.28e-031387176M734
PathwayREACTOME_SIGNALING_BY_NOTCH4

MAML1 MAML3

4.30e-0382172M594
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

MAML1 MAML3

4.30e-0382172MM15922
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

CHD9 NCOA6

4.50e-0384172M1008
PathwayREACTOME_RAC2_GTPASE_CYCLE

ARHGAP17 TIAM1

4.93e-0388172M41810
PathwayREACTOME_RAC3_GTPASE_CYCLE

ARHGAP17 TIAM1

5.61e-0394172M41818
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML1 MAML3

5.84e-0396172M27784
PathwayREACTOME_MITOCHONDRIAL_BIOGENESIS

CHD9 NCOA6

5.84e-0396172M26973
PathwayWP_THERMOGENESIS

ARID1B CREB5

7.34e-03108172M39746
PathwayREACTOME_ADIPOGENESIS

CHD9 NCOA6

7.60e-03110172M48259
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

CHD9 NCOA6

8.70e-03118172M27316
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

MAML1 MAML3

8.85e-03119172M607
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

KMT2C NCOA6

9.28e-03122172M29689
PathwayREACTOME_GASTRULATION

MAML1 MAML3

1.03e-02129172M46433
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MAML1 MED12L TMEM131L KMT2C NCOA6 ARID1B UBAP2

6.86e-0852925714621295
Pubmed

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

KMT2C NCOA6 ZNF281

9.34e-081325317761849
Pubmed

Interaction network of human early embryonic transcription factors.

MAML1 BCL9L KMT2C NCOA6 ARID1B ZNF281

1.53e-0735125638297188
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

MAML1 CSTF2 BCL9L ARHGAP17 NCOA6 CREB5

4.68e-0742525624999758
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

MAML1 BCL9L KMT2C NCOA6 ARID1B MAML3

7.14e-0745725632344865
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MAML1 BCL9L NCOA6 ARID1B ZNF281

1.23e-0626825533640491
Pubmed

Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling.

MAML1 MAML3

1.49e-06325212386158
Pubmed

Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.

KMT2C NCOA6

1.49e-06325218372346
Pubmed

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.

KMT2C NCOA6

1.49e-06325221330447
Pubmed

Human transcription factor protein interaction networks.

MAML1 CSTF2 BCL9L KMT2C NCOA6 ARID1B UBAP2 ZNF281

4.61e-06142925835140242
Pubmed

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

KMT2C NCOA6

7.43e-06625217021013
Pubmed

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.

KMT2C NCOA6

1.04e-05725219433796
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

KMT2C NCOA6

1.04e-05725219556342
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MAML1 CSTF2 TMEM131L ARHGAP17 ARID1B UBAP2

1.08e-0573325634672954
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

MAML1 MAML3

1.78e-05925212370315
Pubmed

External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane.

ARHGAP17 TIAM1

2.22e-051025222750946
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGAP17 NCOA6 ALPK1 UBAP2 TIAM1 CCSER1

2.68e-0586125636931259
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA6 ARID1B ZNF281

2.90e-058325328794006
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CSTF2 KMT2C NCOA6 ARID1B UBAP2

3.94e-0554925538280479
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

KMT2C NCOA6

4.49e-051425212482968
Pubmed

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

CSTF2 KMT2C

4.49e-051425219136632
Pubmed

The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.

KMT2C NCOA6

5.18e-051525217925232
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KMT2C ALPK1 UBAP2

5.53e-0510325310819331
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

KMT2C NCOA6

5.92e-051625223870121
Pubmed

Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo.

MAML1 MAML3

5.92e-051625222069191
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

KMT2C NCOA6

5.92e-051625224368734
Pubmed

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.

KMT2C NCOA6

6.70e-051725226180087
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

KMT2C NCOA6

7.54e-051825217500065
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

MAML1 TICRR ZNF281

7.88e-0511625330804394
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MAML1 NCOA6 ARID1B ZNF281 MAML3

8.02e-0563825531182584
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

KMT2C NCOA6

9.35e-052025229785026
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

KMT2C NCOA6

9.35e-052025219047629
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MAML1 CHD9 KMT2C NCOA6 ARID1B ZNF281

1.06e-04110325634189442
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

KMT2C NCOA6

1.14e-042225226886794
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

MAML1 MAML3

1.60e-042625224391519
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

BMI1 NCOA6 ARID1B

1.93e-0415725330186101
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PKNOX2 BMI1 NCOA6 UBAP2

2.37e-0443025435044719
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CSTF2 TICRR KMT2C NCOA6 ZNF281 INIP

2.53e-04129425630804502
Pubmed

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.

MAML1 CHD9 MAML3

3.03e-0418325336129980
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

BCL9L KMT2C EYA1 ZNF281

3.30e-0446925427634302
Pubmed

Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.

TMEM131L KMT2C

4.00e-044125234638806
Pubmed

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

MAML1 NCOA6

4.00e-04412528724849
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

BMI1 KMT2C NCOA6 ZNF281

4.04e-0449525427705803
Pubmed

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.

ZNF281 MAML3 CREB5

4.34e-0420725326238476
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

BMI1 KMT2C

4.61e-044425224183668
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CSTF2 NCOA6 ARID1B UBAP2 ZNF281

5.17e-0495425536373674
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

MAML1 CHD9 ZNF281

5.32e-0422225337071664
Pubmed

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.

KMT2C NCOA6

5.48e-044825227703004
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KMT2C NCOA6 ALPK1

5.53e-0422525312168954
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

KMT2C NCOA6

5.95e-045025237974198
InteractionEGR2 interactions

MAML1 BCL9L KMT2C NCOA6 ARID1B ZNF281

5.30e-08171256int:EGR2
InteractionTBXT interactions

MAML1 KMT2C NCOA6 ARID1B ZNF281

2.81e-07116255int:TBXT
InteractionPAX9 interactions

MAML1 BCL9L KMT2C NCOA6 ARID1B

4.95e-07130255int:PAX9
InteractionTLX3 interactions

MAML1 BCL9L KMT2C NCOA6 ARID1B ZNF281

1.21e-06291256int:TLX3
InteractionSP7 interactions

MAML1 BCL9L KMT2C NCOA6 ARID1B ZNF281

1.56e-06304256int:SP7
InteractionKLF5 interactions

MAML1 KMT2C NCOA6 ARID1B ZNF281

3.66e-06195255int:KLF5
InteractionGATA2 interactions

BMI1 KMT2C NCOA6 ARID1B ZNF281

4.04e-06199255int:GATA2
InteractionFEV interactions

MAML1 KMT2C NCOA6 ARID1B ZNF281

4.45e-06203255int:FEV
InteractionSOX17 interactions

KMT2C NCOA6 ARID1B ZNF281

5.43e-0695254int:SOX17
InteractionSOX9 interactions

KMT2C NCOA6 ARID1B ZNF281

5.90e-0697254int:SOX9
InteractionERG interactions

MAML1 KMT2C NCOA6 ARID1B ZNF281

7.04e-06223255int:ERG
InteractionEWSR1 interactions

MAML1 CSTF2 BMI1 BCL9L ARHGAP17 NCOA6 ZNF281 CREB5

8.83e-06906258int:EWSR1
InteractionNUP35 interactions

MAML1 BCL9L KMT2C NCOA6 ARID1B MAML3

1.06e-05424256int:NUP35
InteractionTBR1 interactions

MAML1 BCL9L KMT2C ARID1B

1.08e-05113254int:TBR1
InteractionPAX7 interactions

MAML1 KMT2C ARID1B ZNF281

1.56e-05124254int:PAX7
InteractionAR interactions

MAML1 MED12L BMI1 BCL9L KMT2C NCOA6 ARID1B ZNF281

1.71e-05992258int:AR
InteractionHNF4A interactions

BMI1 KMT2C NCOA6 ARID1B ZNF281

1.94e-05275255int:HNF4A
InteractionNFIB interactions

MAML1 KMT2C ARID1B ZNF281

2.66e-05142254int:NFIB
InteractionSOX2 interactions

MAML1 BMI1 BCL9L CHD9 KMT2C NCOA6 ARID1B EYA1 ZNF281

3.06e-051422259int:SOX2
InteractionKDM6A interactions

BMI1 KMT2C NCOA6 ZNF281

4.46e-05162254int:KDM6A
InteractionTLX1 interactions

MAML1 KMT2C ARID1B ZNF281

6.03e-05175254int:TLX1
InteractionPIP interactions

ALPK1 UBAP2 EYA1 TIAM1

6.87e-05181254int:PIP
InteractionHNF1B interactions

MAML1 KMT2C ARID1B ZNF281

8.29e-05190254int:HNF1B
InteractionTLE3 interactions

MAML1 CSTF2 BCL9L ARID1B ZNF281

8.60e-05376255int:TLE3
InteractionNUP43 interactions

BCL9L CHD9 NCOA6 ARID1B CSMD3 ZNF281

9.29e-05625256int:NUP43
InteractionASCL2 interactions

KMT2C NCOA6

1.14e-0413252int:ASCL2
InteractionSOX7 interactions

MAML1 KMT2C ARID1B

1.40e-0482253int:SOX7
InteractionCDK8 interactions

MAML1 MED12L TICRR ZNF281

1.51e-04222254int:CDK8
InteractionGSC interactions

BCL9L KMT2C ARID1B

1.67e-0487253int:GSC
InteractionSOX10 interactions

ARID1B TIAM1 ZNF281

1.97e-0492253int:SOX10
InteractionSS18L1 interactions

CSTF2 BMI1 ARID1B

2.37e-0498253int:SS18L1
InteractionCRX interactions

MAML1 BCL9L KMT2C ARID1B

2.53e-04254254int:CRX
InteractionMAML3 interactions

MAML1 MAML3

2.77e-0420252int:MAML3
InteractionNOTCH4 interactions

MAML1 MAML3

3.06e-0421252int:NOTCH4
InteractionPAX8 interactions

MAML1 KMT2C ARID1B

3.42e-04111253int:PAX8
InteractionUTY interactions

KMT2C NCOA6

3.68e-0423252int:UTY
InteractionRYR3 interactions

BMI1 TIAM1

4.01e-0424252int:RYR3
InteractionFOS interactions

KMT2C NCOA6 ARID1B CREB5

5.51e-04312254int:FOS
InteractionSLX4 interactions

MAML1 CSTF2 CHD9 ZNF281 CREB5

6.00e-04572255int:SLX4
InteractionTLX2 interactions

KMT2C ARID1B ZNF281

7.03e-04142253int:TLX2
InteractionCREBBP interactions

MAML1 BMI1 NCOA6 ARID1B TIAM1

7.40e-04599255int:CREBBP
InteractionFBXO38 interactions

MAML1 TICRR ZNF281

7.47e-04145253int:FBXO38
InteractionWDR33 interactions

CSTF2 BMI1 TIAM1

7.47e-04145253int:WDR33
InteractionELF5 interactions

KMT2C ARID1B ZNF281

7.77e-04147253int:ELF5
InteractionLMX1B interactions

PKNOX2 CREB5

8.57e-0435252int:LMX1B
InteractionFBLN5 interactions

BMI1 ARID1B CREB5

9.76e-04159253int:FBLN5
InteractionKLF4 interactions

KMT2C ARID1B ZNF281

9.93e-04160253int:KLF4
InteractionPAX6 interactions

KMT2C NCOA6 ARID1B ZNF281

1.00e-03366254int:PAX6
InteractionNR3C1 interactions

MAML1 CHD9 NCOA6 ARID1B ZNF281 MAML3

1.01e-03974256int:NR3C1
InteractionLHX4 interactions

BCL9L KMT2C ARID1B

1.10e-03166253int:LHX4
InteractionTEAD1 interactions

KMT2C ARID1B ZNF281

1.31e-03176253int:TEAD1
Cytoband3q25.1

MED12L IGSF10

1.49e-04332523q25.1
CytobandEnsembl 112 genes in cytogenetic band chr4q31

TMEM131L MAML3

3.61e-03164252chr4q31
CytobandEnsembl 112 genes in cytogenetic band chr3q25

MED12L IGSF10

4.32e-03180252chr3q25
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

MED12L TICRR KMT2C UBAP2

2.05e-05180244M8239
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_DN

ARHGAP17 CHD9 ARID1B TIAM1

2.24e-05184244M6739
CoexpressionGSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP

TMEM131L CHD9 TIAM1 CCSER1

3.10e-05200244M7168
CoexpressionBUSSLINGER_DUODENAL_TUFT_CELLS

CHD9 KMT2C CCSER1

5.49e-0581243M40033
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

PKNOX2 IGSF10 TMEM131L TICRR CHD9 NCOA6 EYA1 ZNF281 CREB5

7.23e-061252259facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

PKNOX2 TMEM131L TICRR CHD9 NCOA6 ZNF281 CREB5 CCSER1

6.44e-051257258facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasB cells, preB.FrD.BM, CD19+ IgM- CD45R+ CD43-, Bone marrow, avg-3

TMEM131L ARHGAP17 TICRR ARID1B EYA1

7.34e-05383255GSM399448_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

PKNOX2 TMEM131L TICRR CHD9 NCOA6 ZNF281 CREB5 CCSER1

1.83e-041459258facebase_RNAseq_e10.5_Emin_LatNas_2500
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MED12L ALPK1 MAML3 CCSER1

2.23e-061682546501495b7ad252af330b18011696c43031541018
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KMT2C ARID1B MAML3 CCSER1

3.87e-06193254779276e775cb2492e8dd36436295a536084a6415
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED12L CHD9 CSMD3 MAML3

4.03e-06195254a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

KMT2C ARID1B MAML3 CCSER1

4.37e-0619925494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellremission-multiplets|World / disease stage, cell group and cell class

MED12L IGSF10 ALPK1

6.73e-05142253286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCellremission-multiplets|remission / disease stage, cell group and cell class

MED12L IGSF10 ALPK1

7.76e-05149253e9974260a5f2999b363f306cae005698c912893a
ToppCelldroplet-Lung-nan-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED12L TMEM131L TICRR

8.23e-0515225377b319f594d5e4df29034bbf69c7490076f89dd3
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MED12L IGSF10 CCSER1

8.39e-0515325391e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED12L IGSF10 CCSER1

8.39e-05153253f17f62646633cf95c810dcd5328978058741b276
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

IGSF10 EYA1 CCSER1

8.56e-051542534e9203c220a44c70cd7979796a0b461991422257
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP17 EYA1 MAML3

9.94e-0516225393bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellInt-URO-Myeloid-tDC|Int-URO / Disease, Lineage and Cell Type

MED12L IGSF10 OVOS2

1.05e-041652539803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 CSMD3 CCSER1

1.07e-04166253b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 CSMD3 CCSER1

1.07e-0416625313027ae342994db4540e64eb910df1f42b160931
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGSF10 ALPK1 CREB5

1.23e-04174253e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L IGSF10 TMEM131L

1.23e-04174253fde40c5d51f5380088360dc5a583eb04e518deb6
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

IGSF10 ALPK1 CREB5

1.27e-04176253bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3 CREB5

1.27e-0417625305ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellmegakaryocytic|World / Lineage and Cell class

MED12L IGSF10 OVOS2

1.45e-04184253b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MED12L IGSF10 MAML3

1.50e-04186253722da08cd978249a19855fd3ec8ddda780c99d83
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KMT2C CSMD3 CREB5

1.50e-0418625323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

MED12L IGSF10 OVOS2

1.50e-04186253acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAML1 CHD9 TIAM1

1.52e-041872533699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAML1 CHD9 TIAM1

1.52e-04187253033ba52c0c2f9978784947098fa697368ae44834
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TMEM131L KMT2C ARID1B

1.54e-04188253ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IGSF10 TIAM1 CSMD3

1.57e-04189253203c80030df08ae112f9ae4043709f455d87ce89
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

EYA1 CREB5 CCSER1

1.59e-0419025393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellmegakaryocytic-CD34+_Megakaryoblast|World / Lineage and Cell class

MED12L IGSF10 OVOS2

1.59e-041902531d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM131L ARHGAP17 ARID1B

1.62e-041912534aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM131L ARHGAP17 ARID1B

1.62e-04191253318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

ARID1B TIAM1 CREB5

1.67e-041932537426c291bac59e539c427bcaae18abc7d397d44e
ToppCellfacs-Marrow-B-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM131L ARHGAP17 ARID1B

1.67e-0419325324c34c6635eb7fc2878282803c421b64320e77d8
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

TMEM131L CHD9 CCSER1

1.67e-041932532eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM131L CHD9 CCSER1

1.69e-04194253d852aebf7a763b9a776c4570711f0c759f591910
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

CHD9 ARID1B TIAM1

1.72e-041952536a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

TIAM1 MAML3 CREB5

1.74e-04196253cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B MAML3 CCSER1

1.74e-04196253ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

MAML3 CREB5 CCSER1

1.77e-041972533388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYA1 TIAM1 CREB5

1.80e-04198253c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B MAML3 CCSER1

1.80e-041982531996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYA1 TIAM1 CREB5

1.82e-041992538d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-04200253dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-04200253a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-0420025321bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-042002533bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-0420025333036d21c1c82109284473a515c4f890b33fdd5c
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L TIAM1 MAML3

1.85e-04200253a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ALPK1 TIAM1

1.28e-03952523d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

TICRR CHD9

2.10e-031222521ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ALPK1 CREB5

2.53e-031342527b237690a3765d974f6f813ef2d01154bc23b9d6
ToppCellCOVID-19_Mild-Myeloid_G-Neutrophil|COVID-19_Mild / Disease group, lineage and cell class

ALPK1 CREB5

2.56e-03135252e9eb2bebb6d19c439c83f46c12ca0d676db69de8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3

2.60e-031362529cf076597e6fd9390850fda259daa13022f15893
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED12L IGSF10

2.64e-031372526d90da42dcc06aa895f920218055068f3c76d57d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

TICRR UBAP2

2.68e-0313825293497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c3-LAMP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L CCSER1

2.71e-03139252bb2b020dda32ddc60ec9952de5b01acee60b5b59
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA1 TIAM1

2.71e-03139252fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA1 CREB5

2.71e-03139252a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCelldroplet-Heart-nan-3m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED12L TMEM131L

2.75e-03140252ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ALPK1 EYA1

2.83e-031422526a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ALPK1 EYA1

2.83e-03142252671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSTF2 BCL9L

2.83e-03142252a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ALPK1 EYA1

2.83e-031422523557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ALPK1 EYA1

2.83e-03142252a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSTF2 BCL9L

2.83e-03142252d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGSF10 TICRR

2.87e-031432524622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF10 TICRR

2.87e-031432529836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3

2.91e-031442527de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CREB5

2.91e-031442520322fef818a963be00535d5f141f028d43de5c6a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CREB5

2.95e-03145252590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellBAL-Control-cDC_4|Control / Compartment, Disease Groups and Clusters

NCOA6 CCSER1

2.95e-031452523b2a2965dc18abd39d5ed70c0fcad0210e7f12c8
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MED12L CSMD3

2.99e-03146252bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TIAM1 CSMD3

2.99e-03146252ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TIAM1 ZNF281

2.99e-031462527748277cf2f12e2930d4f5a22247ab9bc266a954
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA1 CREB5

2.99e-0314625210839a4fce2e62955a90592f927a6e0c6a84bbad
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

TICRR CREB5

3.07e-03148252de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TIAM1 CSMD3

3.11e-0314925261d84838a841ed2d6b8c5f86d423a4e6b3dcc9cb
ToppCellLymphoid-Lymphoid-B_cells|Lymphoid / shred on cell class and cell subclass (v4)

TMEM131L ARHGAP17

3.15e-031502525ebf6b4b9b029422a4676ba09a6a9225bd25db47
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED12L IGSF10

3.15e-03150252408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGSF10 ALPK1

3.23e-03152252595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA1 CREB5

3.27e-03153252499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3

3.27e-031532529c6fce56300ba5053efda59a438d63a808c497c0
ToppCellAdult-Epithelial-basal_cell-D175|Adult / Lineage, Cell type, age group and donor

MED12L EYA1

3.27e-031532529ee3e7f3f19a2474283c1c79045269686f35a541
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MED12L PKNOX2

3.27e-03153252489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3

3.36e-031552523b8def9e8f66511736ea37f259511f7c8b7743af
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAML3 CCSER1

3.36e-031552529a27558c457f05808af07190b7a5006b047f1d58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TIAM1 MAML3

3.36e-03155252231fbbbd6e6f9c86be7a15a9ec0804e6b9ab3b5f
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

IGSF10 ALPK1

3.36e-03155252216a240bfb82cdefc59e2f342689dbaaacb7c184
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TIAM1 CSMD3

3.36e-0315525299e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MED12L CCSER1

3.36e-031552529f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAML3 CCSER1

3.36e-03155252ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MED12L PKNOX2

3.40e-031562526365b69ede98bc866e996bc52736b00401aacf6f
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

MED12L MAML3

3.40e-03156252bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

MED12L MAML3

3.40e-03156252159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MED12L PKNOX2

3.44e-03157252bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCelldroplet-Kidney-nan-18m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAML3 CREB5

3.44e-03157252eb64a4e89843895d16015c7d51805f164ed7ea5b
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

IGSF10 EYA1

3.49e-031582528e48952af0831a1fc71ad422e8216b5a92a75991
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA1 MAML3

3.49e-0315825291d265e95156f16459924d3e4dd11c180e164eee
ToppCellTCGA-Thryoid-Solid_Tissue_Normal|TCGA-Thryoid / Sample_Type by Project: Shred V9

IGSF10 EYA1

3.49e-0315825255214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

IGSF10 EYA1

3.49e-03158252e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

OVOS2 ARHGAP17

3.49e-031582522af7beb48272e5368d9ba6b80f08d47ab8556c08
Diseasecalcium measurement

NCOA6 ARID1B EYA1 ZNF281 CREB5

1.31e-04628245EFO_0004838
DiseaseHirschsprung Disease

BMI1 ARID1B

2.91e-0431242C0019569
DiseaseCongenital Heart Defects

EYA1 MAML3

5.87e-0444242C0018798
Diseaseperipheral arterial disease

CSMD3 CCSER1

8.84e-0454242EFO_0004265
Diseaseresponse to efavirenz, virologic response measurement

IGSF10 TIAM1

1.02e-0358242EFO_0006904, EFO_0006906
Diseaseankle injury

CHD9 CCSER1

1.05e-0359242EFO_1002021
Diseasegranulocyte percentage of myeloid white cells

MAML1 CHD9 CREB5

1.30e-03268243EFO_0007997
Diseasecongenital heart disease (implicated_via_orthology)

CHD9 KMT2C

1.44e-0369242DOID:1682 (implicated_via_orthology)
DiseaseDNA methylation

EYA1 TIAM1 CREB5 CCSER1

1.81e-03656244GO_0006306
Diseaseplatelet measurement

MED12L TMEM131L CHD9

2.07e-03315243EFO_0005036
Diseasesusceptibility to Mycobacterium tuberculosis infection measurement

TMEM131L CREB5

2.22e-0386242EFO_0008407
Diseaseunipolar depression

EYA1 CSMD3 MAML3 CREB5 CCSER1

2.51e-031206245EFO_0003761
DiseaseNeurodevelopmental Disorders

KMT2C ARID1B

2.59e-0393242C1535926
Disease3-hydroxypropylmercapturic acid measurement

MED12L IGSF10 UBAP2

2.83e-03352243EFO_0007014
DiseaseAdenoid Cystic Carcinoma

KMT2C MAML3

2.99e-03100242C0010606
Diseasetestosterone measurement

PKNOX2 NCOA6 ARID1B EYA1 CSMD3

3.20e-031275245EFO_0004908
Diseasemultiple myeloma

TICRR CCSER1

3.73e-03112242EFO_0001378
Diseasecognitive function measurement

MED12L ARID1B CSMD3 MAML3 CCSER1

5.28e-031434245EFO_0008354
Diseaseinsomnia measurement

MED12L CSMD3 CCSER1

5.38e-03443243EFO_0007876
Diseaselung non-small cell carcinoma (is_implicated_in)

KMT2C ARID1B

5.68e-03139242DOID:3908 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LNMSEGSNSSNQPHG

CSMD3

3611

Q7Z407
GGQMHAGISSFQQSN

ARID1B

891

Q8NFD5
ISANNQMHGQGPSQP

ARID1B

946

Q8NFD5
NLSISNGAQPGHSNM

CCSER1

86

Q9C0I3
AGPGSGSNVSMNQQN

CSTF2

211

P33240
GNQPGNMLNCSQNSS

ALPK1

911

Q96QP1
HTGNQAQVSPATQQM

CREB5

336

Q02930
NSSWQHQGMPNLSGQ

MAML1

836

Q92585
ASSNSPMHSQGQQFS

KMT2C

2336

Q8NEZ4
NNSSNSGMSLFNPNS

MED12L

1371

Q86YW9
NQSGMSITHNQAQGP

MAML3

886

Q96JK9
STMNGTSNSPSGNHQ

BMI1

291

P35226
GNSHINSNSMTPNGT

EYA1

26

Q99502
QQMNSHGGFSSNQVI

OVOS2

1216

Q6IE36
GIHGNMNNQQAGTSG

NCOA6

586

Q14686
NHPPQMTNASNSQQS

CHD9

211

Q3L8U1
PTMSSQIQGTTNQHS

IGSF10

876

Q6WRI0
GISNSQPSQMHLNSA

BCL9L

1136

Q86UU0
NSPNSMSGVSNNPQG

PKNOX2

201

Q96KN3
RQNASSSSQQNNGPM

TMEM131L

906

A2VDJ0
QNQPQAAAGSHQLSM

ARHGAP17

601

Q68EM7
MQNQSSTNHPGASIA

INIP

31

Q9NRY2
TNSQHNNQMAPGTGS

UBAP2

326

Q5T6F2
AFMGTPQNQTHQQPH

TICRR

1256

Q7Z2Z1
ATNPQISHSNSMQGR

TIAM1

301

Q13009
TSAEPGSSNHTNMGN

ZNF281

376

Q9Y2X9