Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscellular response to unfolded protein

HERPUD2 RHBDD1 PIK3R1

8.56e-05100183GO:0034620
GeneOntologyBiologicalProcessN-glycan processing

GANAB MAN1A2

9.71e-0517182GO:0006491
GeneOntologyBiologicalProcessresponse to endoplasmic reticulum stress

HERPUD2 RHBDD1 PIK3R1 MAN1A2

1.07e-04295184GO:0034976
GeneOntologyBiologicalProcesscellular response to topologically incorrect protein

HERPUD2 RHBDD1 PIK3R1

1.33e-04116183GO:0035967
GeneOntologyBiologicalProcessresponse to unfolded protein

HERPUD2 RHBDD1 PIK3R1

2.73e-04148183GO:0006986
GeneOntologyBiologicalProcessresponse to topologically incorrect protein

HERPUD2 RHBDD1 PIK3R1

3.82e-04166183GO:0035966
DomainCOS_domain

TRIM9 TRIM67

5.12e-0512172IPR017903
DomainCOS

TRIM9 TRIM67

5.12e-0512172PS51262
DomainBBC

TRIM9 TRIM67

8.13e-0515172SM00502
DomainBbox_C

TRIM9 TRIM67

8.13e-0515172IPR003649
DomainBBOX

TRIM9 TRIM67

1.76e-0369172SM00336
Domain-

TRIM9 TRIM67

1.87e-03711724.10.45.10
Domainzf-B_box

TRIM9 TRIM67

1.92e-0372172PF00643
DomainZF_BBOX

TRIM9 TRIM67

2.36e-0380172PS50119
DomainZnf_B-box

TRIM9 TRIM67

2.42e-0381172IPR000315
DomainSPRY

TRIM9 TRIM67

2.79e-0387172SM00449
DomainSPRY

TRIM9 TRIM67

3.24e-0394172PF00622
DomainSPRY_dom

TRIM9 TRIM67

3.24e-0394172IPR003877
DomainB30.2/SPRY

TRIM9 TRIM67

3.31e-0395172IPR001870
DomainB302_SPRY

TRIM9 TRIM67

3.31e-0395172PS50188
Domainfn3

TRIM9 TRIM67

9.34e-03162172PF00041
DomainZnf_RING_CS

TRIM9 TRIM67

9.45e-03163172IPR017907
DomainZnf_C3HC4_RING-type

TRIM9 TRIM67

1.05e-02172172IPR018957
DomainFN3

TRIM9 TRIM67

1.20e-02185172SM00060
DomainFN3

TRIM9 TRIM67

1.38e-02199172PS50853
DomainFN3_dom

TRIM9 TRIM67

1.52e-02209172IPR003961
DomainConA-like_dom

TRIM9 TRIM67

1.66e-02219172IPR013320
Domainzf-C3HC4

TRIM9 TRIM67

1.72e-02223172PF00097
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS

GANAB MAN1A2

5.41e-0516102M47632
PathwayBIOCARTA_ERAD_PATHWAY

GANAB MAN1A2

7.70e-0519102M22013
Pubmed

A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.

TRIM9 TRIM67

1.52e-06418231820781
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HERPUD2 LRP4 WDR17 TRIM9 PIK3R1 CNOT3 MAN1A2

2.06e-06128518735914814
Pubmed

Mammalian TRIM67 Functions in Brain Development and Behavior.

TRIM9 TRIM67

3.79e-06618229911180
Pubmed

TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.

TRIM9 TRIM67

5.30e-06718222337885
Pubmed

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.

BCHE PIK3R1

2.29e-051418223419831
Pubmed

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

GANAB MAN1A2

3.42e-05171822355006
Pubmed

Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.

GANAB MAN1A2

4.78e-052018212560567
Pubmed

Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.

GANAB MAN1A2

5.81e-05221829109416
Pubmed

Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.

GANAB MAN1A2

5.81e-052218211530211
Pubmed

Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.

GANAB MAN1A2

5.81e-05221828673525
Pubmed

Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.

GANAB MAN1A2

6.36e-05231821736542
Pubmed

Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.

GANAB MAN1A2

6.36e-05231823099781
Pubmed

Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.

GANAB MAN1A2

6.36e-05231828093218
Pubmed

Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.

GANAB MAN1A2

6.36e-05231823264072
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

GANAB MAN1A2

7.54e-05251822283726
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

GANAB MAN1A2

8.16e-05261828218172
Pubmed

Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.

GANAB MAN1A2

1.67e-04371822542563
Pubmed

Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.

GANAB MAN1A2

1.67e-04371822541446
Pubmed

Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.

GANAB MAN1A2

1.76e-04381822829950
Pubmed

Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.

GANAB MAN1A2

1.76e-04381822187500
Pubmed

Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.

GANAB MAN1A2

2.58e-04461822649653
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRP4 RHBDD1 GANAB MAN1A2 DSEL

2.87e-04120118535696571
InteractionMYO16 interactions

TRIM9 PIK3R1 TRIM67

2.77e-0716173int:MYO16
InteractionPRMT7 interactions

PRMT7 GANAB TRIM67

7.90e-0647173int:PRMT7
InteractionDSEL interactions

TRIM67 DSEL

1.00e-056172int:DSEL
InteractionRNASEH2B interactions

HERPUD2 PIK3R1 TRIM67

1.49e-0558173int:RNASEH2B
InteractionKBTBD2 interactions

PIK3R1 TRIM67

4.40e-0512172int:KBTBD2
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM9 TRIM67

1.46e-039511259
GeneFamilyFibronectin type III domain containing

TRIM9 TRIM67

4.06e-03160112555
GeneFamilyRing finger proteins

TRIM9 TRIM67

1.16e-0227511258
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BCHE NXPH2 TRPC4

2.33e-051401832c44e8cc5190226049be7ebc465d685393e701c4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE NXPH2 DSEL

3.73e-051641834a4c32d242db97216cb345e59865c2c826c8b9f2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE NXPH2 DSEL

5.00e-0518118370eff83dd85691e977972c660731394d2fcf5cdf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE NXPH2 TRPC4

5.08e-05182183f00eec1f434d92d44787d3d3343476c98c3de5b4
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRP4 TRIM9 BCHE

5.08e-05182183ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH2 TRPC4 TRIM67

5.25e-051841831158a55c1990fd23d270cb6510d0951c4bfcddc5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4 MMEL1

5.25e-051841837d41784eac0935e77d6bc701f20c693adf998730
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 BCHE DSEL

6.33e-05196183455a2a1c98da413c8e9617b964b6ed141ed3a3be
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 PIK3R1 MAN1A2

6.33e-0519618345d1c0a962c4221c17393ee5566961d1deebf442
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP4 NXPH2 TRPC4

6.33e-0519618357df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

WDR17 MAN1A2 DSEL

6.62e-05199183121de4e02585de3a3010398387c523bacf8ce546
ToppCell10x_3'_v2v3-Neoplastic|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 BCHE DSEL

6.72e-05200183e9c7d7cb5fa63fc92aa91d02ae8bd05438d465bc
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

NXPH2 TRPC4 TRIM67

6.72e-05200183f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

NXPH2 TRPC4 TRIM67

6.72e-0520018370a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

NXPH2 TRPC4 TRIM67

6.72e-052001831639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))-|Thalamus / BrainAtlas - Mouse McCarroll V32

NXPH2 MMEL1

3.49e-046918210d5fccc1fa10ffc9051df42dd0e5046d97ec4af
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))|Thalamus / BrainAtlas - Mouse McCarroll V32

NXPH2 MMEL1

3.49e-04691829d7e911434c6b18327fa7adaec5c449e0c300919
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PIK3R1 TRPC4

1.12e-0312418236dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NXPH2 TRPC4

1.16e-031261823a14d4eb8803827946c36faeeb7ae2913418d421
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-2|TCGA-Brain / Sample_Type by Project: Shred V9

LRP4 TRIM67

1.17e-03127182018ffd9ff1913787cb0086a8581b399a121eaba1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3R1 NXPH2

1.21e-031291826abdba987c8528f7cb90b32dc01796e02c7352c9
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM9 NXPH2

1.36e-03137182b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM9 NXPH2

1.36e-03137182cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM9 NXPH2

1.36e-031371825d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRMT7 RHBDD1

1.40e-031391827e2c10830c3d16109cab3ed0d64b3532481e497d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PRMT7 GANAB

1.51e-0314418257d2846ec26d4490ec11c171af447b17a729437e
ToppCellCOVID-19_Severe-MAIT|World / disease group, cell group and cell class

PGAP2 DSEL

1.53e-031451828d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCellCOVID-19_Severe-MAIT|COVID-19_Severe / disease group, cell group and cell class

PGAP2 DSEL

1.63e-03150182923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCellBAL-Mild-Myeloid-TRAM-TRAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

WDR17 DSEL

1.65e-0315118245392bb1c6358beff33da0ca84f7696fb5824f30
ToppCellBAL-Mild-Myeloid-TRAM-TRAM2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

WDR17 DSEL

1.65e-031511823d861285c71abe220b19a069eb9876199c6c8f39
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NXPH2 TRIM67

1.67e-031521829391b46a441cf031665df1d142e3f65e98675eeb
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAN1A2 MMEL1

1.67e-03152182eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

BCHE PIK3R1

1.70e-031531821524557514668f515ac1bbe847611f564b265b42
ToppCellMild_COVID-19-Myeloid-TRAM2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

WDR17 DSEL

1.72e-03154182ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCellnormal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PIK3R1 DSEL

1.74e-0315518208295584395e8d9cfc1b1648f98754b3ac53e587
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

BCHE TRIM67

1.74e-031551821882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

BCHE NXPH2

1.76e-03156182e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 BCHE

1.81e-03158182c736834269c89e003c61a62b63e4e50dbf0e1538
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9|TCGA-Colorectal / Sample_Type by Project: Shred V9

WDR17 BCHE

1.83e-03159182f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCellControl-Mast_cells-Transitioning_MDM|Control / group, cell type (main and fine annotations)

LRP4 TRPC4

1.88e-031611825807ee48f871a3eb24ebf78fd107cf5f2a4ec846
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

1.88e-031611821b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM9 PIK3R1

1.92e-031631824dfd408aa700e307478ee35f6b902f68719d8d9e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDR17 TRIM67

1.92e-0316318299cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDR17 TRIM67

1.92e-03163182510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

1.94e-03164182f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 BCHE

1.99e-0316618237f5264491d75af690dd94eea2cf7763f42b2a2a
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRIM9 TRPC4

2.02e-0316718249b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH2 TRPC4

2.02e-03167182904a42309ef3a3695bd74c3737c6bec25b742677
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.02e-03167182b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.02e-0316718294fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.02e-03167182eff3723fe60755272eca237459165e436e919ece
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.04e-031681822eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM9 MMEL1

2.04e-03168182a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM9 TRPC4

2.09e-03170182941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE NXPH2

2.11e-031711822c7d73f1386ddd172839734c68ed3859a90f80f8
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PGAP2 DSEL

2.11e-03171182f3bf5805823d5733b58742172e7668725ce82931
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.14e-0317218208a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.14e-031721821ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.14e-03172182553701349444eb366df3c11f54bb093434f153c6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.14e-03172182ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.14e-031721824ae0a3ba4660fc9292b7e9a3087a25a3349d8965
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM9 BCHE

2.14e-03172182bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.16e-031731820d38206e25434386b1aec2078067efc67b496c10
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM9 TRPC4

2.18e-03174182f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRIM9 TRPC4

2.18e-031741828393f0b43c767839c1630bcb952d62b42efc788d
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM9 BCHE

2.18e-03174182b31a6c9d8f7c8cb229c0539d959c19251e2fcd13
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 BCHE

2.21e-031751823f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BCHE PIK3R1

2.21e-031751821799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TRIM9 BCHE

2.21e-03175182ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell356C-Lymphocytic-ILC|356C / Donor, Lineage, Cell class and subclass (all cells)

HERPUD2 PIK3R1

2.21e-031751827fa8330ce813c48bd332be618909e5ec8d0f5d7e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.21e-0317518229a4197ad4b2382257d7cc9ff237726bb60bc06d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|356C / Donor, Lineage, Cell class and subclass (all cells)

HERPUD2 PIK3R1

2.23e-031761829399e174d14e81cc977fcb48facf844ee6726603
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH2 TRPC4

2.23e-03176182322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC4 TRIM67

2.23e-03176182682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH2 TRPC4

2.26e-03177182c20df760b25caa772278397b02fc36521927cbfc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.26e-031771822b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE TRPC4

2.26e-031771825e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIM9 BCHE

2.26e-03177182c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCHE PIK3R1

2.26e-031771827af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L6_SST_NPY_(Sst_Chodl)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCHE NXPH2

2.26e-031771820979e3a9150b3ebc64fe045792a7740a82f7bc2e
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCHE PIK3R1

2.28e-031781820fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell356C-Lymphocytic-ILC-ILC-1|356C / Donor, Lineage, Cell class and subclass (all cells)

HERPUD2 PIK3R1

2.28e-0317818240df4bb0978e5e5568c52ad4a5881ea0cdc6941d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP4 DSEL

2.28e-03178182c87945146b2734141f07b39d268e0d8086ee0364
ToppCellfacs|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 PGAP2

2.31e-031791828001db3044e8657980e24422377c4fdb0d7b323e
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRIM9 TRIM67

2.31e-03179182e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

TRIM9 TRPC4

2.31e-03179182342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRIM9 TRPC4

2.31e-03179182df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCellfacs-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 BCHE

2.31e-03179182bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC4 TRIM67

2.33e-031801828f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

BCHE TRPC4

2.33e-031801827085a851807e6a833965e1366946db0bbc5174e2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 BCHE

2.36e-03181182b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LRP4 TRPC4

2.36e-0318118247dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LRP4 TRPC4

2.36e-0318118219103221c3a5a16b16378348004b2c50caee4f01
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRIM9 TRPC4

2.36e-03181182fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP4 BCHE

2.39e-031821823cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP4 BCHE

2.39e-031821828a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM9 TRPC4

2.39e-03182182d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCHE TRPC4

2.39e-031821827b86703559438e2d5ef3dad963ee0d772513f313
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP4 BCHE

2.39e-031821825d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP4 BCHE

2.39e-03182182831b5ce46b41efe01c4db6016c2f43148611373d
Drugmalaoxon

BCHE TRPC4

2.87e-0511172ctd:C100082
DrugAC1L1DXE

BCHE PIK3R1 TRPC4 MMEL1

6.06e-05299174CID000002548
Drughydroxyl radicals

TRIM9 BCHE NXPH2 GANAB MAN1A2 MMEL1

2.91e-041341176CID000000961
DrugPentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A

LRP4 CNOT3 TRPC4

3.91e-041961733387_UP
DrugClorsulon [60200-06-8]; Down 200; 10.6uM; HL60; HG-U133A

TRIM9 PIK3R1 PGAP2

3.91e-041961731735_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A

PRMT7 BCHE PGAP2

3.97e-041971731215_DN
DrugXylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A

LRP4 TRIM9 PIK3R1

4.03e-041981732107_UP
DrugGlutethimide, para-amino [125-84-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A

PRMT7 CNOT3 PGAP2

4.09e-041991737421_DN
Drugtime t

BCHE MMEL1

7.07e-0453172CID000004790
Drugferulic acid

BCHE PIK3R1

8.46e-0458172ctd:C004999
Drug4-DAMP

BCHE TRPC4

1.06e-0365172CID000001734
Drugparamethoxyphenyl-acetyl dehydroalanine

BCHE MMEL1

1.20e-0369172CID000130300
Drug2,4,6-trinitrotoluene

TRIM9 TRPC4

1.41e-0375172CID000008376
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

TRIM9 TRIM67

4.68e-066172DOID:0080697 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
WKAGFHRWNNYMMDW

BCHE

571

P06276
HRWNNYMMDWKNQFN

BCHE

576

P06276
WRFHTKYMMWFQRHE

CNOT3

696

O75175
MAYADSMENFWDWLA

NXPH2

71

O95156
TNMAFHMTAWWDFGN

PGAP2

226

Q9UHJ9
GMNNNMSLQDAEWYW

PIK3R1

321

P27986
NMMDWWSNFSTQHFR

MMEL1

631

Q495T6
EEMQWRDHWMQCVYF

PRMT7

306

Q9NVM4
EMMKHAWDNYRTYGW

MAN1A2

186

O60476
FSPLQMLWWQQMYAH

HERPUD2

186

Q9BSE4
NNLDNNWLKMHFWFY

DSEL

301

Q8IZU8
ADDWHLYFNMASMLW

RHBDD1

76

Q8TEB9
TMRAWWANMFSYDNY

GANAB

516

Q14697
MAWMTYISNWFEQDD

WDR17

1

Q8IZU2
KAWAMYVDNNRSWFM

TRIM67

686

Q6ZTA4
ACHQTWNHNNMFWYR

TRBV10-1

41

A0A0K0K1A3
WNHNNMFWYRQDLGH

TRBV10-1

46

A0A0K0K1A3
WAMYVDNNRSWFMHN

TRIM9

616

Q9C026
HDWWNLMDFVMNSLY

TRPC4

431

Q9UBN4
HEMGFMYWTDWGENA

LRP4

1176

O75096