Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionarachidonate 12(S)-lipoxygenase activity

ALOX5 ALOX15

1.28e-044932GO:0004052
GeneOntologyBiologicalProcessregulation of cellular component size

RHOA SPTBN4 ARHGAP40 SLC12A4 PCLO RTN4 SPTB LRP1 MACF1 PRKD1 TNR ALOX15

5.35e-074269412GO:0032535
GeneOntologyBiologicalProcessregulation of anatomical structure size

RHOA SPTBN4 DOCK4 ARHGAP40 SLC12A4 PCLO RTN4 SPTB LRP1 MACF1 PRKD1 TNR ALOX5 ALOX15

7.78e-076189414GO:0090066
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

RHOA SPTBN4 RHOC RHOG ARHGAP40 MAP1S GAS2L2 SPTB HSPH1 LRP1 NUBP1 PRKD1 ALOX15

2.21e-065799413GO:0051493
GeneOntologyBiologicalProcessresponse to calcium ion

CPNE8 CPNE9 PDCD6 TRPC1 TRPV6 APOBEC1 ALOX15

8.97e-06161947GO:0051592
GeneOntologyBiologicalProcessskeletal muscle satellite cell migration

RHOA RHOC

2.05e-052942GO:1902766
GeneOntologyBiologicalProcessmicrotubule-based process

RHOA TBC1D32 SPIRE2 BNIP2 DNAH12 MAP1S GAS2L2 DNAH10 TTLL2 ARHGEF1 HSPH1 UHRF1 NUBP1 MACF1 PARD3B ESPL1

2.16e-0510589416GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

RHOA TBC1D32 SPIRE2 BNIP2 MAP1S GAS2L2 TTLL2 ARHGEF1 HSPH1 UHRF1 NUBP1 PARD3B ESPL1

2.29e-057209413GO:0000226
GeneOntologyBiologicalProcessprotein depolymerization

RHOA SPTBN4 MAP1S GAS2L2 ARHGEF1 SPTB

5.13e-05144946GO:0051261
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

RHOA SPTBN4 RHOC RHOG ARHGAP40 SPTB LRP1 PRKD1 ALOX15

6.46e-05384949GO:0032956
GeneOntologyBiologicalProcessactin cytoskeleton organization

RHOA SPTBN4 RHOB RHOC RHOG SPIRE2 ARHGAP40 GAS2L2 PCLO SPTB LRP1 PRKD1 ALOX15

7.02e-058039413GO:0030036
GeneOntologyBiologicalProcessregulation of cell size

RHOA SLC12A4 RTN4 LRP1 MACF1 PRKD1 TNR

7.67e-05225947GO:0008361
GeneOntologyBiologicalProcesssupramolecular fiber organization

RHOA SPTBN4 RHOB RHOC RHOG SPIRE2 ARHGAP40 MAP1S GAS2L2 ARHGEF1 SPTB PRKD1 P3H4 ALOX15

1.07e-049579414GO:0097435
GeneOntologyBiologicalProcessactin filament organization

RHOA SPTBN4 RHOB RHOC RHOG SPIRE2 ARHGAP40 GAS2L2 SPTB ALOX15

1.08e-045099410GO:0007015
GeneOntologyBiologicalProcessregulation of axon extension involved in regeneration

LRP1 TNR

1.23e-044942GO:0048690
GeneOntologyBiologicalProcesslipoxin biosynthetic process

ALOX5 ALOX15

1.23e-044942GO:2001301
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RHOA DOCK4 RHOB RHOC RHOG BNIP2 ARHGAP40 ARHGEF1 RTN4 FAM13B

1.70e-045389410GO:0007264
GeneOntologyBiologicalProcessregulation of actin filament-based process

RHOA SPTBN4 RHOC RHOG ARHGAP40 SPTB LRP1 PRKD1 ALOX15

1.75e-04438949GO:0032970
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

RHOA SPTBN4 RHOC ARHGAP40 MAP1S GAS2L2 SPTB PRKD1 ALOX15

1.75e-04438949GO:1902903
GeneOntologyBiologicalProcessresponse to wounding

RHOA RHOC SIGLEC16 LRP1 MUC16 DUOX2 MACF1 TNR ALOX5 ALOX15 FERMT3

2.03e-046599411GO:0009611
GeneOntologyBiologicalProcessaxon extension involved in regeneration

LRP1 TNR

2.04e-045942GO:0048677
GeneOntologyBiologicalProcessregulation of sprouting of injured axon

LRP1 TNR

2.04e-045942GO:0048686
GeneOntologyBiologicalProcesslipoxin metabolic process

ALOX5 ALOX15

2.04e-045942GO:2001300
GeneOntologyBiologicalProcessactin filament polymerization

RHOA SPTBN4 SPIRE2 ARHGAP40 SPTB ALOX15

2.35e-04190946GO:0030041
GeneOntologyBiologicalProcessmicrotubule depolymerization

RHOA MAP1S GAS2L2 ARHGEF1

2.35e-0466944GO:0007019
GeneOntologyBiologicalProcessactin filament-based process

RHOA SPTBN4 RHOB RHOC RHOG SPIRE2 ARHGAP40 GAS2L2 PCLO SPTB LRP1 PRKD1 ALOX15

2.48e-049129413GO:0030029
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

RHOA RHOB RHOC SPIRE2 ESPL1

2.90e-04127945GO:0061640
GeneOntologyBiologicalProcesssprouting of injured axon

LRP1 TNR

3.05e-046942GO:0048682
GeneOntologyBiologicalProcessregulation of organelle organization

RHOA SPTBN4 RHOC RHOG ARHGAP40 MAP1S GAS2L2 SPTB HSPH1 NFRKB LRP1 NUBP1 ZNF205 PRKD1 ESPL1 ALOX15

3.48e-0413429416GO:0033043
GeneOntologyBiologicalProcesscleavage furrow formation

RHOA SPIRE2

4.25e-047942GO:0036089
GeneOntologyBiologicalProcesspositive regulation of cell motility

RHOA DOCK4 RHOB RHOC PDCD6 RTN4 LRP1 DUOX2 PRKD1 NIPBL FERMT3

4.57e-047259411GO:2000147
GeneOntologyBiologicalProcessregulation of response to wounding

SIGLEC16 LRP1 MUC16 DUOX2 TNR ALOX5

4.77e-04217946GO:1903034
GeneOntologyBiologicalProcessreactive oxygen species biosynthetic process

RHOA DUOX2 ZNF205 ALOX5

4.91e-0480944GO:1903409
GeneOntologyBiologicalProcessactin polymerization or depolymerization

RHOA SPTBN4 SPIRE2 ARHGAP40 SPTB ALOX15

5.38e-04222946GO:0008154
GeneOntologyBiologicalProcesspositive regulation of locomotion

RHOA DOCK4 RHOB RHOC PDCD6 RTN4 LRP1 DUOX2 PRKD1 NIPBL FERMT3

5.54e-047429411GO:0040017
GeneOntologyBiologicalProcessregulation of cell motility

RHOA DOCK4 RHOB RHOC TMIGD1 PDCD6 GAS2L2 RTN4 LRP1 DUOX2 MACF1 PRKD1 TNR NIPBL FERMT3

6.50e-0412809415GO:2000145
GeneOntologyBiologicalProcessmembrane invagination

RHOA SNX3 SPIRE2 ALOX15

6.74e-0487944GO:0010324
GeneOntologyBiologicalProcessregulation of developmental growth

SPTBN4 CPNE9 RTN4 LRP1 MACF1 TNR ZNF416 NIPBL

6.79e-04421948GO:0048638
GeneOntologyBiologicalProcessregulation of actin filament polymerization

RHOA SPTBN4 ARHGAP40 SPTB ALOX15

7.41e-04156945GO:0030833
GeneOntologyBiologicalProcessregulation of lipase activity

RHOA RHOC LRP1

8.62e-0441943GO:0060191
GeneOntologyBiologicalProcessmembrane organization

RHOA SPTBN4 SNX3 SPIRE2 PDCD6 TOMM6 YIPF4 RTN4 SPTB ZNF205 ATP8B2 ALOX15

8.99e-049149412GO:0061024
GeneOntologyBiologicalProcesscellular response to hydroperoxide

TMIGD1 PRKD1

9.03e-0410942GO:0071447
GeneOntologyBiologicalProcessGolgi vesicle transport

SNX3 SPIRE2 PDCD6 YIPF4 COPB2 MACF1 PRKD1

9.17e-04339947GO:0048193
GeneOntologyBiologicalProcessmodification of postsynaptic structure

RHOA RHOB SPTB

9.25e-0442943GO:0099010
GeneOntologyBiologicalProcessmitotic cytokinesis

RHOA RHOB RHOC ESPL1

9.38e-0495944GO:0000281
GeneOntologyBiologicalProcessregulation of locomotion

RHOA DOCK4 RHOB RHOC TMIGD1 PDCD6 GAS2L2 RTN4 LRP1 DUOX2 MACF1 PRKD1 TNR NIPBL FERMT3

9.40e-0413279415GO:0040012
GeneOntologyCellularComponentcell cortex

RHOA SPTBN4 FNBP1 SPIRE2 PCLO SPTB MACF1 PARD3B POLR2M PRKD1

6.61e-063719410GO:0005938
GeneOntologyCellularComponentcleavage furrow

RHOA RHOB RHOC SPIRE2

1.64e-0461944GO:0032154
GeneOntologyCellularComponentanchoring junction

RHOA SPTBN4 RHOB RHOG TMIGD1 RTN4 LRP1 DUOX2 PARD3B POLR2M PRKD1 PCDH1 FERMT3

4.17e-049769413GO:0070161
GeneOntologyCellularComponentcell division site

RHOA RHOB RHOC SPIRE2

4.67e-0480944GO:0032153
GeneOntologyCellularComponentspectrin

SPTBN4 SPTB

7.06e-049942GO:0008091
GeneOntologyCellularComponentinner dynein arm

DNAH12 DNAH10

8.79e-0410942GO:0036156
DomainRHO

RHOA RHOB RHOC RHOG

2.51e-0620924PS51420
DomainDUF5050

LRP1 LRP1B

2.40e-052922IPR032485
DomainDUF5050

LRP1 LRP1B

2.40e-052922PF16472
DomainLH2

LOXHD1 ALOX5 ALOX15

8.95e-0518923SM00308
DomainSpectrin_bsu

SPTBN4 SPTB

1.43e-044922IPR016343
DomainPLAT

LOXHD1 ALOX5 ALOX15

1.44e-0421923PS50095
Domain-

LOXHD1 ALOX5 ALOX15

1.44e-04219232.60.60.20
DomainPLAT

LOXHD1 ALOX5 ALOX15

1.44e-0421923PF01477
DomainPLAT/LH2_dom

LOXHD1 ALOX5 ALOX15

1.44e-0421923IPR001024
DomainActinin_actin-bd_CS

SPTBN4 SPTB MACF1

1.91e-0423923IPR001589
DomainSpectrin

SPTBN4 SPTB MACF1

1.91e-0423923PF00435
DomainACTININ_2

SPTBN4 SPTB MACF1

1.91e-0423923PS00020
DomainACTININ_1

SPTBN4 SPTB MACF1

1.91e-0423923PS00019
DomainCH

SPTBN4 GAS2L2 SPTB MACF1

2.97e-0465924SM00033
DomainLipOase_mml

ALOX5 ALOX15

3.55e-046922IPR001885
DomainLIPOXYGENASE_1

ALOX5 ALOX15

3.55e-046922PS00711
DomainLipOase_C

ALOX5 ALOX15

3.55e-046922IPR013819
DomainLipoxygenase

ALOX5 ALOX15

3.55e-046922PF00305
DomainLIPOXYGENASE_3

ALOX5 ALOX15

3.55e-046922PS51393
DomainGAR

GAS2L2 MACF1

3.55e-046922PS51460
DomainLIPOXYGENASE_2

ALOX5 ALOX15

3.55e-046922PS00081
DomainLipOase

ALOX5 ALOX15

3.55e-046922IPR000907
Domain-

GAS2L2 MACF1

3.55e-0469223.30.920.20
DomainLipOase_Fe_BS

ALOX5 ALOX15

3.55e-046922IPR020833
DomainLipOase_CS

ALOX5 ALOX15

3.55e-046922IPR020834
DomainGAS_dom

GAS2L2 MACF1

3.55e-046922IPR003108
DomainGAS2

GAS2L2 MACF1

3.55e-046922PF02187
DomainGAS2

GAS2L2 MACF1

3.55e-046922SM00243
DomainSpectrin_repeat

SPTBN4 SPTB MACF1

3.85e-0429923IPR002017
DomainCH

SPTBN4 GAS2L2 SPTB MACF1

3.94e-0470924PF00307
Domain-

SPTBN4 GAS2L2 SPTB MACF1

4.16e-04719241.10.418.10
DomainCH

SPTBN4 GAS2L2 SPTB MACF1

4.63e-0473924PS50021
DomainCH-domain

SPTBN4 GAS2L2 SPTB MACF1

5.13e-0475924IPR001715
DomainSpectrin/alpha-actinin

SPTBN4 SPTB MACF1

5.17e-0432923IPR018159
DomainSPEC

SPTBN4 SPTB MACF1

5.17e-0432923SM00150
DomainCopine

CPNE8 CPNE9

8.45e-049922PF07002
DomainCopine

CPNE8 CPNE9

8.45e-049922IPR010734
DomainTRP_channel

TRPC1 TRPV6

1.28e-0311922IPR004729
Domain6-blade_b-propeller_TolB-like

LGI3 LRP1 LRP1B

1.51e-0346923IPR011042
DomainQuinoprot_gluc/sorb_DH

LGI3 LRP1

1.53e-0312922IPR011041
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH10

2.10e-0314922IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH10

2.10e-0314922IPR013602
DomainDHC_N2

DNAH12 DNAH10

2.10e-0314922PF08393
DomainAAA_8

DNAH12 DNAH10

2.10e-0314922PF12780
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH10

2.10e-0314922IPR011704
DomainLdl_recept_b

LRP1 LRP1B

2.10e-0314922PF00058
DomainLDLRB

LRP1 LRP1B

2.10e-0314922PS51120
DomainAAA_5

DNAH12 DNAH10

2.10e-0314922PF07728
DomainDHC_fam

DNAH12 DNAH10

2.42e-0315922IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH10

2.42e-0315922IPR004273
DomainDynein_heavy

DNAH12 DNAH10

2.42e-0315922PF03028
DomainLY

LRP1 LRP1B

2.42e-0315922SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B

2.42e-0315922IPR000033
DomainIon_trans_dom

CACNA1F KCNG2 TRPC1 TRPV6

2.43e-03114924IPR005821
DomainIon_trans

CACNA1F KCNG2 TRPC1 TRPV6

2.43e-03114924PF00520
DomainGRAM

GRAMD1B GRAMD2A

2.75e-0316922SM00568
DomainRas

RHOA RHOB RHOC RHOG

4.58e-03136924PF00071
PathwayREACTOME_RHO_GTPASES_ACTIVATE_ROCKS

RHOA RHOB RHOC

1.55e-065773MM15221
PathwayREACTOME_RHO_GTPASES_ACTIVATE_CIT

RHOA RHOB RHOC

5.40e-067773MM15217
PathwayREACTOME_RHO_GTPASES_ACTIVATE_RHOTEKIN_AND_RHOPHILINS

RHOA RHOB RHOC

1.29e-059773M27551
PathwayREACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE

RHOA RHOB RHOC

2.51e-0511773MM15046
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

RHOA RHOB RHOC

6.80e-0515773MM15037
PathwayREACTOME_RHO_GTPASE_CYCLE

RHOA DOCK4 RHOB RHOC RHOG FNBP1 CPNE8 ARHGAP40 ARHGEF1 FAM13B

1.31e-044397710MM15595
PathwayREACTOME_RHO_GTPASES_ACTIVATE_ROCKS

RHOA RHOB RHOC

1.43e-0419773M27493
PathwayREACTOME_RHO_GTPASES_ACTIVATE_CIT

RHOA RHOB RHOC

1.43e-0419773M27489
PathwayREACTOME_RHO_GTPASE_CYCLE

RHOA DOCK4 RHOB RHOC RHOG FNBP1 CPNE8 ARHGAP40 ARHGEF1 FAM13B

1.61e-044507710M27078
PathwayREACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE

RHOA RHOB RHOC

1.67e-0420773M18415
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PKNS

RHOA RHOB RHOC

2.57e-0423773MM15216
PathwayREACTOME_BIOSYNTHESIS_OF_E_SERIES_18_S_RESOLVINS

ALOX5 ALOX15

2.91e-045772MM15617
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

RHOA RHOB RHOC

2.92e-0424773M2243
PathwayREACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS

ALOX5 ALOX15

4.36e-046772M27890
PathwayWP_METABOLISM_OF_ALPHALINOLENIC_ACID

ALOX5 ALOX15

4.36e-046772M39844
PathwayREACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS

ALOX5 ALOX15

4.36e-046772MM15615
PathwayPID_P75_NTR_PATHWAY

RHOA RHOB RHOC RTN4

5.14e-0468774M153
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

RHOA RHOB RHOC ARHGEF1

8.23e-0477774MM15044
PathwayREACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE

RHOA RHOB RHOG

9.04e-0435773MM14512
PathwayREACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE

RHOA RHOB RHOG

9.04e-0435773M773
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

RHOA RHOB RHOC ARHGEF1

9.50e-0480774M800
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY

RHOA ARHGEF1

1.03e-039772M47546
PathwayREACTOME_P75NTR_REGULATES_AXONOGENESIS

RHOA RTN4

1.03e-039772MM14745
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN4 SPTB

1.29e-0310772MM15112
PathwayREACTOME_P75NTR_REGULATES_AXONOGENESIS

RHOA RTN4

1.29e-0310772M27073
PathwayREACTOME_RHO_GTPASES_ACTIVATE_KTN1

RHOA RHOG

1.57e-0311772M27490
PathwayREACTOME_RHO_GTPASES_ACTIVATE_KTN1

RHOA RHOG

1.57e-0311772MM15218
Pubmed

RhoA, RhoB and RhoC have different roles in cancer cell migration.

RHOA RHOB RHOC

1.91e-08394323488932
Pubmed

Divergence of Rho residue 43 impacts GEF activity.

RHOA RHOB RHOC

1.91e-08394322673745
Pubmed

A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.

RHOA RHOB RHOC

1.91e-08394312939257
Pubmed

The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells.

RHOA RHOB RHOC

1.91e-08394326741994
Pubmed

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases.

RHOA RHOB RHOC

1.91e-08394329500478
Pubmed

RhoA, RhoB and RhoC differentially regulate endothelial barrier function.

RHOA RHOB RHOC

1.91e-08394328949796
Pubmed

Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.

RHOA RHOB RHOC

1.91e-08394315642170
Pubmed

Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells.

RHOA RHOB RHOC

1.91e-08394327147504
Pubmed

Rho isoforms have distinct and specific functions in the process of epithelial to mesenchymal transition in renal proximal tubular cells.

RHOA RHOB RHOC

1.91e-08394319477269
Pubmed

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.

RHOA RHOB RHOC

7.63e-0849438662891
Pubmed

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization.

RHOA RHOB RHOC

7.63e-08494310559899
Pubmed

XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.

RHOA RHOB RHOC

7.63e-08494312221096
Pubmed

Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.

RHOA RHOB RHOC

7.63e-08494322992742
Pubmed

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

RHOA RHOB RHOC

1.90e-0759438617235
Pubmed

Rho localization in cells and tissues.

RHOA RHOB RHOC

1.90e-07594315093731
Pubmed

A novel partner for the GTP-bound forms of rho and rac.

RHOA RHOB RHOC

1.90e-0759438543060
Pubmed

Small GTP-binding proteins and the regulation of the actin cytoskeleton.

RHOA RHOB RHOC

3.80e-0769437888179
Pubmed

Rho GTPases and the actin cytoskeleton.

RHOA RHOB RHOC

3.80e-0769439438836
Pubmed

The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases.

RHOA RHOB RHOC

3.80e-07694319286565
Pubmed

RHO binding to FAM65A regulates Golgi reorientation during cell migration.

RHOA RHOB RHOC

6.64e-07794327807006
Pubmed

Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS.

RHOA ARHGEF1 RTN4

6.64e-07794312951563
Pubmed

Roles of glial p75NTR in axonal regeneration.

RHOA ARHGEF1 RTN4

1.06e-06894317335080
Pubmed

The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

RHOA ARHGEF1 RTN4

1.06e-06894312692556
Pubmed

Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1.

RHOA RHOB RHOC

1.59e-06994315151987
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

RHOA RHOB RHOG THEM6 NSUN4 PDCD6 MAP1S SND1 ARHGEF1 RTN4 HSPH1 MACF1 CHID1 NIPBL P3H4

2.03e-061297941533545068
Pubmed

The HIV-1 vpr protein induces anoikis-resistance by modulating cell adhesion process and microfilament system assembly.

RHOA RHOB RHOG

2.26e-061094310713718
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

RHOA RHOB RHOC ARHGEF1

3.44e-063894419911011
Pubmed

Kctd13 deletion reduces synaptic transmission via increased RhoA.

RHOA RHOB RHOC

5.36e-061394329088697
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SPTBN4 GRAMD1B MAP1S SND1 ARHGEF1 PCLO LGI3 RTN4 SPTB HSPH1 COPB2 PPP1R18 MACF1 TNR PCDH1

6.67e-061431941537142655
Pubmed

A high expression ratio of RhoA/RhoB is associated with the migratory and invasive properties of basal-like Breast Tumors.

RHOA RHOB

7.23e-06294233162807
Pubmed

RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts.

RHOA RHOC

7.23e-06294221454503
Pubmed

Identification of Rho GEF and RhoA Activation by Pull-Down Assays.

RHOA ARHGEF1

7.23e-06294232808262
Pubmed

Activation of a bacterial virulence protein by the GTPase RhoA.

RHOA RHOC

7.23e-06294219887681
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

7.23e-06294215963947
Pubmed

Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.

ALOX5 ALOX15

7.23e-06294234706241
Pubmed

Coding sequence of human rho cDNAs clone 6 and clone 9.

RHOB RHOC

7.23e-0629423283705
Pubmed

Kindlin-3 and RASSF6 are probable biomarkers for predicting metastasis in cutaneous melanoma.

RASSF6 FERMT3

7.23e-06294235048636
Pubmed

Functional analysis of the promoters of the small GTPases RhoA and RhoB in embryonic stem cells.

RHOA RHOB

7.23e-06294228739254
Pubmed

A novel ras-related gene family.

RHOB RHOC

7.23e-0629423888408
Pubmed

Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB.

RHOA RHOB

7.23e-06294229059167
Pubmed

Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.

RHOA RHOC

7.23e-06294212808121
Pubmed

Chromosome localization of human ARH genes, a ras-related gene family.

RHOA RHOB

7.23e-0629422407642
Pubmed

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.

RHOA FERMT3

7.23e-06294224615351
Pubmed

Endothelial RhoB and RhoC are dispensable for leukocyte diapedesis and for maintaining vascular integrity during diapedesis.

RHOB RHOC

7.23e-06294228960175
Pubmed

GTPases Rho distribution in intraepithelial and invasive neoplasias of the uterine cervix.

RHOA RHOB

7.23e-06294224984542
Pubmed

ABCs of RhoGTPases indicating potential role as oncotargets.

RHOA RHOC

7.23e-06294228508825
Pubmed

Immunolocalization of RhoA and RhoB GTPases in pleomorphic adenoma of the parotid.

RHOA RHOB

7.23e-06294225454559
Pubmed

Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.

RHOA RHOC

7.23e-06294219499974
Pubmed

Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease.

ALOX5 ALOX15

7.23e-06294221558275
Pubmed

RhoA enhances store-operated Ca2+ entry and intestinal epithelial restitution by interacting with TRPC1 after wounding.

RHOA TRPC1

7.23e-06294226336927
Pubmed

Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers.

RHOA RHOC

7.23e-06294220503409
Pubmed

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

RHOA RHOC

7.23e-0629427989340
Pubmed

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids.

ALOX5 ALOX15

7.23e-06294219497113
Pubmed

Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer.

RHOA RHOC

7.23e-06294233825439
Pubmed

Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.

RHOA RHOC

7.23e-06294220828398
Pubmed

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

RHOA RHOC

7.23e-06294215668138
Pubmed

Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.

ALOX5 ALOX15

7.23e-06294222516296
Pubmed

Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1.

RHOA ARHGEF1

7.23e-06294229071730
Pubmed

Ovarian clear cell carcinomas: RHO GTPases may contribute to explain their singular biologic behavior.

RHOA RHOC

7.23e-06294221208644
Pubmed

Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.

RHOA RHOC

7.23e-06294219642867
Pubmed

Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma.

RHOA RHOC

7.23e-06294217896152
Pubmed

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

TRPC1 TRPV6

7.23e-06294222932896
Pubmed

Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.

RHOA RHOC

7.23e-0629427835413
Pubmed

Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury.

ALOX5 ALOX15

7.23e-06294220008149
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTBN4 SPTB

2.16e-05394211294830
Pubmed

Calcium store contents control the expression of TRPC1, TRPC3 and TRPV6 proteins in LNCaP prostate cancer cell line.

TRPC1 TRPV6

2.16e-05394216529812
Pubmed

CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity.

RHOA RHOB

2.16e-05394231148579
Pubmed

Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.

ALOX5 ALOX15

2.16e-05394222825379
Pubmed

[Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway].

RHOA ARHGEF1

2.16e-05394225916117
Pubmed

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

ALOX5 ALOX15

2.16e-05394218346986
Pubmed

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness.

RHOA RHOB

2.16e-05394224782506
Pubmed

Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction.

RHOA ARHGEF1

2.16e-05394221473788
Pubmed

Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.

ALOX5 ALOX15

2.16e-05394215328042
Pubmed

RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability.

RHOA TRPC1

2.16e-05394212766172
Pubmed

RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.

RHOA RHOB

2.16e-05394218524772
Pubmed

Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.

RHOA RHOC

2.16e-05394217018591
Pubmed

RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7).

RHOA RHOC

2.16e-05394224096540
Pubmed

Structural and mechanistic insights into the interaction between Rho and mammalian Dia.

RHOA RHOC

2.16e-05394215864301
Pubmed

Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.

RHOA RHOC

2.16e-05394219421144
Pubmed

Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.

RHOA RHOB

2.16e-05394218694745
Pubmed

Loss of cell-cell contacts induces NF-kappaB via RhoA-mediated activation of protein kinase D1.

RHOA PRKD1

2.16e-05394219173301
Pubmed

Down expression of LRP1B promotes cell migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in renal cell cancer.

RHOA LRP1B

2.16e-05394223521319
Pubmed

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

RHOA RTN4

2.16e-05394231062076
Pubmed

Dock4 is regulated by RhoG and promotes Rac-dependent cell migration.

DOCK4 RHOG

2.16e-05394217027967
Pubmed

miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.

RHOA ARHGEF1

2.16e-05394223070684
Pubmed

SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.

RHOA RHOC

2.16e-05394221242305
Pubmed

5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.

ALOX5 ALOX15

2.16e-05394230407793
Pubmed

Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation.

RHOA RHOG

2.16e-05394211909943
Pubmed

Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.

ALOX5 ALOX15

2.16e-05394229167447
Pubmed

A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.

RHOA RHOC

2.16e-05394221087931
Pubmed

The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.

ALOX5 ALOX15

2.16e-0539428944751
Pubmed

RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.

RHOA RHOC

2.16e-05394220697357
Pubmed

Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases.

RHOA RHOC

2.16e-05394224447566
Pubmed

Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.

RHOA RHOB

2.16e-05394211788600
Pubmed

RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.

RHOA RHOB

2.16e-05394211741970
Pubmed

Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients.

RHOA RHOC

2.16e-05394231324164
Pubmed

Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway.

RHOA FERMT3

2.16e-05394231907416
Pubmed

Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells.

RHOB RHOG

2.16e-05394227832197
Pubmed

Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.

ALOX5 ALOX15

2.16e-05394223079635
Pubmed

Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein.

CPNE8 CPNE9

2.16e-05394211123945
InteractionITGA5 interactions

RHOA RHOB RHOC RHOG FBXO6 BTNL3 RTN4 PCDH1

1.41e-07127948int:ITGA5
InteractionADGRG6 interactions

RHOA RHOB RHOC RHOG FBXO6

6.67e-0736945int:ADGRG6
InteractionITGA6 interactions

RHOA RHOB RHOC RHOG FBXO6 BTNL3 RTN4 COPB2

6.82e-07156948int:ITGA6
InteractionCRIM1 interactions

RHOA RHOB RHOC RHOG

2.50e-0621944int:CRIM1
InteractionB2M interactions

RHOA RHOB RHOC RHOG MAP1S DOT1L

4.52e-0692946int:B2M
InteractionEMC10 interactions

RHOA RHOC RHOG FBXO6 TCTN2

5.74e-0655945int:EMC10
InteractionSLITRK4 interactions

RHOA RHOB RHOC RHOG

6.13e-0626944int:SLITRK4
InteractionSPCS2 interactions

RHOA RHOC RHOG FNDC3B FBXO6 TOMM6 TCTN2

6.27e-06149947int:SPCS2
InteractionSLITRK5 interactions

RHOA RHOB RHOC RHOG TCTN2

8.14e-0659945int:SLITRK5
InteractionFLRT2 interactions

RHOA RHOB RHOC RHOG

9.64e-0629944int:FLRT2
InteractionOLR1 interactions

RHOA RHOB RHOC RHOG

9.64e-0629944int:OLR1
InteractionSOWAHC interactions

RHOA RHOB RHOC RHOG

9.64e-0629944int:SOWAHC
InteractionITGAV interactions

RHOA RHOB RHOC RHOG FBXO6 RTN4 TCTN2

1.13e-05163947int:ITGAV
InteractionSLC38A5 interactions

RHOA RHOB RHOG TMEM63B

1.27e-0531944int:SLC38A5
InteractionDCBLD1 interactions

RHOA RHOB RHOC RHOG

1.27e-0531944int:DCBLD1
InteractionOSBPL3 interactions

RHOA RHOB RHOC RHOG SND1 DOT1L

1.27e-05110946int:OSBPL3
InteractionFLOT1 interactions

RHOA RHOB RHOC RHOG CPNE8 ARHGAP40 SLC12A4 PCLO TMEM63B MACF1 DOT1L

1.32e-054759411int:FLOT1
InteractionSCARB1 interactions

RHOA RHOB RHOC RHOG FBXO6 BTNL3

1.41e-05112946int:SCARB1
InteractionSLC16A7 interactions

RHOA RHOB RHOC RHOG

1.44e-0532944int:SLC16A7
InteractionPLCB4 interactions

RHOA RHOB RHOC RHOG

1.44e-0532944int:PLCB4
InteractionTMEM109 interactions

RHOA RHOC RHOG TMEM63B DOT1L TCTN2

1.56e-05114946int:TMEM109
InteractionGRAMD2A interactions

GRAMD1B GRAMD2A BNIP2

1.58e-0511943int:GRAMD2A
InteractionATP11A interactions

RHOA RHOB RHOC RHOG

2.08e-0535944int:ATP11A
InteractionTENM2 interactions

RHOA RHOB RHOC

2.10e-0512943int:TENM2
InteractionPCDH17 interactions

RHOA RHOB RHOC RHOG

2.33e-0536944int:PCDH17
InteractionPLXNA1 interactions

RHOA RHOB RHOC RHOG FBXO6 TCTN2

2.40e-05123946int:PLXNA1
InteractionGNB4 interactions

RHOA RHOB RHOC RHOG FBXO6 DOT1L

2.40e-05123946int:GNB4
InteractionSRPRB interactions

RHOA RHOC RHOG TBC1D32 THEM6 SNX3 FBXO6 TMEM63B TCTN2

2.56e-05333949int:SRPRB
InteractionMUC13 interactions

RHOA RHOB RHOC RHOG

2.61e-0537944int:MUC13
InteractionARHGEF2 interactions

RHOA RHOB FBXO6 ARHGAP40 MAP1S ARHGEF1 RTN4 FERMT3

2.64e-05256948int:ARHGEF2
InteractionDHCR7 interactions

RHOA GRAMD1B RHOB RHOC RHOG TBC1D32 PCLO TCTN2

2.79e-05258948int:DHCR7
InteractionSLC11A2 interactions

RHOA RHOB RHOC RHOG

2.90e-0538944int:SLC11A2
InteractionALPL interactions

RHOB RHOC FBXO6 ALOX5

3.22e-0539944int:ALPL
InteractionTMCO1 interactions

RHOA RHOB RHOC FBXO6 TMEM63B PPP1R13L TCTN2

3.25e-05192947int:TMCO1
InteractionDAG1 interactions

RHOA RHOB RHOC RHOG BTNL3 TCTN2

3.89e-05134946int:DAG1
InteractionCCN1 interactions

RHOA RHOB RHOC RHOG

4.34e-0542944int:CCN1
InteractionATP6AP1 interactions

RHOA RHOC RHOG FBXO6 COPB2 TCTN2

4.98e-05140946int:ATP6AP1
InteractionEPHA7 interactions

RHOA RHOB RHOC RHOG CPNE8 HSPH1 COPB2 P3H4

5.23e-05282948int:EPHA7
InteractionFNDC3A interactions

RHOA GRAMD1B RHOC RHOG FNDC3B PDCD6 BTNL3 HSPH1

6.22e-05289948int:FNDC3A
InteractionITGA1 interactions

RHOA RHOB RHOC RHOG

6.23e-0546944int:ITGA1
InteractionSLCO4A1 interactions

RHOA RHOB RHOC RHOG

6.23e-0546944int:SLCO4A1
InteractionPARD3B interactions

RHOA RHOB RHOC PARD3B

6.23e-0546944int:PARD3B
InteractionMND1 interactions

NSUN4 MAP1S ARHGEF1 ALOX5

6.23e-0546944int:MND1
InteractionATP13A3 interactions

RHOA RHOB RHOC RHOG YIPF4 HCRTR2

6.29e-05146946int:ATP13A3
InteractionERLIN1 interactions

RHOA RHOB BNIP2 FBXO6 COPB2 TMEM63B

6.53e-05147946int:ERLIN1
InteractionRAB18 interactions

RHOA RHOB RHOG TBC1D32 RTN4 COPB2

6.53e-05147946int:RAB18
InteractionMCAM interactions

RHOA RHOB RHOC RHOG CPNE8 SNX3 SLC12A4 PARD3B PCDH1 FERMT3

6.56e-054689410int:MCAM
InteractionBLTP1 interactions

RHOA RHOB RHOC RHOG

8.01e-0549944int:BLTP1
InteractionCYFIP1 interactions

RHOA RHOB RHOC RHOG ARHGEF1 MACF1 DOT1L FERMT3

8.65e-05303948int:CYFIP1
InteractionARHGDIG interactions

RHOA RHOB RHOG

9.02e-0519943int:ARHGDIG
InteractionSLC2A14 interactions

RHOA RHOB RHOG

9.02e-0519943int:SLC2A14
InteractionABCC5 interactions

RHOA RHOB RHOC RHOG

9.38e-0551944int:ABCC5
InteractionCCDC115 interactions

RHOA RHOC RHOG COPB2 TCTN2

1.00e-0499945int:CCDC115
InteractionSPTLC1 interactions

RHOA RHOB RHOC RHOG FBXO6 COPB2

1.01e-04159946int:SPTLC1
InteractionPTPRJ interactions

RHOA RHOB RHOC RHOG FBXO6

1.05e-04100945int:PTPRJ
InteractionCISD2 interactions

GALNT15 RHOA RHOC RHOG RTN4 COPB2 TCTN2

1.10e-04233947int:CISD2
InteractionMYOF interactions

RHOA RHOB RHOC RHOG TMEM63B

1.16e-04102945int:MYOF
InteractionRAB23 interactions

RHOA RHOB RHOC RHOG

1.17e-0454944int:RAB23
InteractionEMC2 interactions

RHOA RHOB RHOC RHOG FBXO6 RTN4 HSPH1 COPB2 TCTN2

1.29e-04411949int:EMC2
InteractionFASLG interactions

RHOA DOCK4 FNBP1 PDCD6 P3H4

1.33e-04105945int:FASLG
InteractionCPNE8 interactions

RHOA RHOB RHOC RHOG CPNE8

1.33e-04105945int:CPNE8
InteractionNSDHL interactions

RHOA RHOB RHOC RHOG COPB2 TCTN2

1.36e-04168946int:NSDHL
InteractionBMPR2 interactions

RHOA RHOB RHOC RHOG TRPC1

1.65e-04110945int:BMPR2
InteractionBSG interactions

RHOA SPTBN4 RHOB RHOC RHOG CPNE8 SNX3 FBXO6 RTN4 SPTB CDC45

1.70e-046319411int:BSG
InteractionSTX10 interactions

RHOA RHOB RHOC RHOG B3GNT7

1.72e-04111945int:STX10
InteractionESYT1 interactions

RHOA RHOB RHOC RHOG THEM6 TOMM6 RTN4 COPB2 TCTN2

1.84e-04431949int:ESYT1
InteractionPLXNB2 interactions

RHOA RHOB RHOC RHOG FBXO6 BTNL3

1.87e-04178946int:PLXNB2
InteractionSTT3A interactions

RHOA RHOB RHOC TBC1D32 FBXO6 DOT1L

1.93e-04179946int:STT3A
InteractionCEP55 interactions

RHOA GRAMD1B RHOB RHOG POLM PPP1R13L CDC45

1.97e-04256947int:CEP55
InteractionCEMIP2 interactions

RHOA RHOB RHOC RHOG FBXO6

2.03e-04115945int:CEMIP2
InteractionLRP10 interactions

RHOA RHOB RHOC RHOG FBXO6

2.03e-04115945int:LRP10
InteractionARHGAP5 interactions

RHOA RHOB RHOC RHOG

2.14e-0463944int:ARHGAP5
InteractionKLHL34 interactions

MAP1S ARHGEF1 PPP1R13L ESPL1

2.14e-0463944int:KLHL34
InteractionNUS1 interactions

RHOA RHOB RHOC TCTN2

2.28e-0464944int:NUS1
InteractionSLC9A1 interactions

RHOA RHOB RHOC RHOG TCTN2

2.29e-04118945int:SLC9A1
InteractionZDHHC8 interactions

RHOA RHOB RHOG

2.36e-0426943int:ZDHHC8
InteractionDDX47 interactions

RHOA RHOB RBM15B DOT1L NIPBL TCTN2

2.37e-04186946int:DDX47
InteractionTMEM87A interactions

RHOA RHOB RHOC RHOG CHID1 P3H4

2.44e-04187946int:TMEM87A
InteractionEMC3 interactions

RHOA RHOC RHOG FBXO6 TCTN2

2.57e-04121945int:EMC3
InteractionTHEM6 interactions

RHOA RHOB RHOC THEM6 DOT1L

2.57e-04121945int:THEM6
InteractionSSR1 interactions

RHOA GRAMD1B RHOC RHOG CPNE8 FBXO6 SND1 RTN4 COPB2

2.66e-04453949int:SSR1
InteractionSLC39A6 interactions

RHOA RHOB RHOC RHOG HCRTR2

2.67e-04122945int:SLC39A6
InteractionSLC22A4 interactions

RHOA RHOB RHOC RHOG RTN4 ATP8B2

2.81e-04192946int:SLC22A4
InteractionDEPDC1B interactions

RHOA RHOB RHOC RHOG COPB2 TCTN2

2.81e-04192946int:DEPDC1B
InteractionSLC20A2 interactions

RHOA RHOB RHOC RHOG

2.88e-0468944int:SLC20A2
InteractionCD99 interactions

RHOA RHOB RHOC RHOG

2.88e-0468944int:CD99
InteractionRAB32 interactions

RHOA RHOB RHOC RHOG

2.88e-0468944int:RAB32
InteractionDIAPH3 interactions

RHOA RHOB RHOC RHOG PDCD6

2.99e-04125945int:DIAPH3
InteractionSTX16 interactions

RHOA RHOB RHOC RHOG

3.04e-0469944int:STX16
InteractionEHD2 interactions

RHOA RHOB RHOC RHOG

3.04e-0469944int:EHD2
InteractionSPCS3 interactions

RHOA RHOC RHOG FBXO6 TCTN2

3.10e-04126945int:SPCS3
InteractionOSBPL8 interactions

RHOA RHOB RHOC RHOG RTN4 COPB2 TCTN2

3.11e-04276947int:OSBPL8
InteractionTMEM185B interactions

RHOA RHOC

3.19e-046942int:TMEM185B
InteractionANO6 interactions

RHOA RHOB RHOC RHOG TCTN2

3.22e-04127945int:ANO6
InteractionSLC7A1 interactions

GALNT15 RHOA RHOB RHOC RHOG YIPF4

3.22e-04197946int:SLC7A1
InteractionSDR39U1 interactions

RHOA RHOB RHOG

3.29e-0429943int:SDR39U1
InteractionIGSF3 interactions

RHOA RHOB RHOG FBXO6

3.40e-0471944int:IGSF3
InteractionSLC19A1 interactions

RHOA RHOB RHOC RHOG

3.40e-0471944int:SLC19A1
InteractionSLC12A4 interactions

RHOA RHOB RHOC RHOG SLC12A4

3.46e-04129945int:SLC12A4
InteractionATP1A1 interactions

RHOA RHOB RHOC RHOG FNDC3B FBXO6 SND1 RTN4 COPB2 TMEM63B

3.48e-045759410int:ATP1A1
GeneFamilyRho family GTPases

RHOA RHOB RHOC RHOG

1.55e-0620794390
GeneFamilyArachidonate lipoxygenases

ALOX5 ALOX15

2.80e-046792407
GeneFamilyEF-hand domain containing|Spectrins

SPTBN4 SPTB

3.90e-0477921113
GeneFamilyCopines

CPNE8 CPNE9

6.65e-049792829
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B

1.43e-0313792634
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

GRAMD1B GRAMD2A

1.43e-03137921146
GeneFamilyDyneins, axonemal

DNAH12 DNAH10

2.46e-0317792536
CoexpressionVERRECCHIA_EARLY_RESPONSE_TO_TGFB1

RHOA RHOB RHOC RHOG LRP1

1.47e-0654945M4737
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOC TRANK1 DNAH10 TOMM6 PCLO LRP1B

1.59e-0616994612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RHOA DOCK4 RHOB FNDC3B PPP1R18 LRP1B

2.29e-06180946cf7d8bf9eee2dfab2c8a6780e296b05ad42041bf
ToppCellmLN-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

SNX3 TRANK1 MAP1S NUBP1 ALOX15

2.30e-06100945c560326f6ae5338aecdf11ef8adf04bc8769745c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F TRANK1 LOXHD1 DNAH10 PCLO LRP1B

2.60e-061849462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F TRANK1 LOXHD1 DNAH10 PCLO LRP1B

2.60e-06184946ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F TRANK1 LOXHD1 DNAH10 PCLO LRP1B

2.60e-061849462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH12 GAS2L2 DNAH10 MUC16 DUOX2 ALOX15

3.64e-0619594679dc031258579ea328181dda33710dd897f1064a
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPIRE2 MAP1S RASSF6 MUC16 CHID1 NAGS

3.97e-06198946dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellNS-critical-d_0-4-Myeloid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK4 RHOG FNDC3B PPP1R18 ALOX5 FERMT3

3.97e-0619894672d51284d267f102c26f0ae8279ee9e11e69c7e3
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

THEM6 SPIRE2 DNAH12 GAS2L2 DNAH10

1.78e-051529455ce8920aedd39a4daf7082153b5e213707c14227
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

DNAH12 GAS2L2 DNAH10 PCLO MUC16

2.01e-0515694510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LOXHD1 LRP1 LRP1B ALOX15 CDC45

2.48e-05163945360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LOXHD1 LRP1 LRP1B ALOX15 CDC45

2.48e-05163945b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRAMD1B KCNG2 TRANK1 ESPL1 FERMT3

2.71e-051669450a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-DC1|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GRAMD2A FNBP1 SNX3 B3GNT7 ALOX15

2.95e-05169945488ba50631a64cb9e0d69219491c66ac824c9e7d
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 APOBEC1 ALOX5 ALOX15 FERMT3

2.95e-05169945b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 APOBEC1 ALOX5 ALOX15 FERMT3

2.95e-0516994583d1bcf33872b01ea9614f608a3e4ab30df25c7e
ToppCellfacs-Aorta-Heart-24m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO48 NUBP1 ESPL1 ALOX5 FERMT3

3.30e-05173945d0d1c8bcef3d9c28ee9a7c64076624b836cb2580
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASSF6 PCLO LGI3 TRPV6 CHGB

3.39e-05174945d22b73b5aed85fb09fbe039f64504e19ebf9acb8
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRAMD2A FNBP1 SNX3 B3GNT7 NAGS

3.49e-05175945398e2504021f587166ad04a2f0662bfcb4e1c0df
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEM6 DNAH12 RASSF6 TTLL2 CHGB

3.58e-0517694571f96cace3f20fbef975037f4deff9b82b0282a1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHOB THEM6 CACNA1F LOXHD1 PCDH1

4.54e-05185945602536a3308a848f106adcb0a83530997440c8f4
ToppCell5'|World / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RHOA RHOB MUC16 DUOX2 ALOX15

5.29e-051919450e752756e9d1b444930522efc0fdca072d42535f
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH12 GAS2L2 DNAH10 MUC16 ALOX15

5.29e-05191945e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B RTN4 MACF1 DOT1L ALOX5

5.42e-051929458b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH12 GAS2L2 DNAH10 MUC16 ALOX15

5.69e-05194945756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RASSF6 MUC16 APOBEC1 CHGB ESPL1

5.69e-05194945d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOA RHOB TOMM6 PPP1R18 FERMT3

6.12e-05197945e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCellfacs-Brain_Myeloid-Cortex_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOA RHOB TOMM6 PPP1R18 FERMT3

6.12e-0519794581379fe6bd14a1ba26f4a159497262adcb600b18
ToppCellfacs-Brain_Myeloid-Cortex_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOA RHOB TOMM6 PPP1R18 FERMT3

6.12e-05197945271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOA RHOB TOMM6 PPP1R18 FERMT3

6.12e-051979459db329c6fea532dd1afb624f4c29c92407f45568
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

GAS2L2 DUOX2 TRPV6 PPP1R13L RNF39

6.27e-05198945e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

GAS2L2 DUOX2 TRPV6 PPP1R13L RNF39

6.27e-05198945ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RASSF6 PCLO CHGB RNF39 ESPL1

6.27e-05198945d6812494874be0c14361ac2ac3e418b335bb8f55
ToppCellmLN-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

PCLO UHRF1 B3GNT7 ESPL1 CDC45

6.42e-05199945c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH12 GAS2L2 DNAH10 MUC16 ALOX15

6.42e-051999452498237b9e895ca4826a3378d9d40989968df72b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH12 GAS2L2 DNAH10 MUC16 ALOX15

6.42e-05199945542ec45c931b40738df1f3777b00c83be33a514a
ToppCell3'-Parenchyma_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RHOA RHOB RHOG RTN4 ALOX5

6.42e-05199945bc064ccfec8c1e96079b89b05aeebddf48bc87f3
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_T_naive|Int-URO / Disease, condition lineage and cell class

SPTBN4 SPTB PARD3B ESPL1 TCTN2

6.58e-05200945a4b531355e87efd6b69a16eeec8b1ff14c7af750
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GRAMD1B PAXBP1 SPTB UHRF1 ATP8B2

6.58e-052009456a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCellBiopsy_Control_(H.)-Immune|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

RHOG LRP1 PPP1R18 ALOX5 FERMT3

6.58e-05200945e1d50556ca116ef4b65ec29ab2ef7341f0d21451
ToppCellmetastatic_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

RHOB FNDC3B RTN4 HSPH1 LRP1

6.58e-052009454758b96725699641b55a665533adf2d238032b09
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-4|TCGA-Colorectal / Sample_Type by Project: Shred V9

SPIRE2 TTLL2 ZNF316 ESPL1

1.61e-04129944003a3202053986c2eb10d5e84b90ab33b7ee37e3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 TRPV6 CHGB LRP1B

1.66e-0413094405d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMIGD1 LRP1 PARD3B CHID1

2.33e-04142944d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMIGD1 LRP1 PARD3B CHID1

2.33e-04142944a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH12 DNAH10 MUC16 ALOX15

2.94e-041519448216462e723fec2797387929dde095370947e10a
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

FBXO48 SPTB UHRF1 LRP1B

3.25e-041559447c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF39 TNR ALOX5 ALOX15

3.41e-04157944ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF39 TNR ALOX5 ALOX15

3.41e-04157944fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellCOVID-19_Severe-PLT_3|World / Disease Group and Platelet Clusters

CACNA1F SNX3 TRPC1 PPP1R18

3.49e-04158944b981592129cd00564a7e44e6ed43fef4585f4700
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRAMD2A APOBEC1 NAGS ALOX15

3.58e-04159944709b57f992a29878cc899d760d144d36cb5cb280
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FBXO48 UHRF1 ESPL1 CDC45

3.75e-041619440dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FBXO48 UHRF1 ESPL1 CDC45

3.75e-04161944b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FBXO48 UHRF1 ESPL1 CDC45

3.75e-04161944efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASSF6 PCLO PCDH1 ALOX5

3.75e-04161944f5df8c6a340d5026726804b103e32137f363ca40
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FBXO48 UHRF1 ESPL1 CDC45

3.75e-0416194428d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH12 RASSF6 PCLO CHGB

3.84e-041629449f568836199a05f696294caac1ea3fa413984423
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASSF6 LGI3 TRPV6 LRP1B

3.84e-041629448e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASSF6 LGI3 TRPV6 LRP1B

3.84e-04162944e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellCOVID-19_Severe-multiplets|World / disease group, cell group and cell class

GRAMD2A UHRF1 B3GNT7 CDC45

3.93e-041639446db4271c2d47a9c333964f36d2c32207115e52cd
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF1 UHRF1 FERMT3 CDC45

4.02e-04164944249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH12 GAS2L2 MUC16 ALOX15

4.02e-041649440e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBEC1 ALOX5 ALOX15 FERMT3

4.11e-04165944518ee34c18065100a2f2c6e407d3a7866b908593
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBEC1 ALOX5 ALOX15 FERMT3

4.11e-04165944becb8f726b84509ec29c75b530a3fe757651301d
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBEC1 ALOX5 ALOX15 FERMT3

4.11e-04165944ae8dd9c00f96590f27ed21cd6314f4577e00e312
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPV6 RNF39 ALOX5 ALOX15

4.21e-04166944c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPV6 RNF39 ALOX5 ALOX15

4.21e-041669440975fc165bcc7e85f053d9d0244fffe407c23571
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT15 UHRF1 ZNF205 CDC45

4.31e-04167944bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellfacs-Large_Intestine-Proximal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMIGD1 RTN4 LRP1 NAGS

4.40e-0416894423e0e1592d7400012d289adb10c7598285bae2e9
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP40 MUC16 PARD3B ALOX15

4.50e-0416994440b557549fe08c5dc9dba359af35993d68d1640a
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF154 UHRF1 ESPL1 CDC45

4.60e-041709445319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FNBP1 SNX3 B3GNT7 ALOX15

4.71e-04171944459e1ac0b89571c39db98c0f578eca8f46caa8e3
ToppCellfacs-GAT-Fat-3m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 APOBEC1 ALOX5 FERMT3

4.71e-041719443f796d53d3110e5d6e97de53bb49d323944659d6
ToppCellfacs-GAT-Fat-3m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 APOBEC1 ALOX5 FERMT3

4.71e-04171944d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCellfacs-GAT-Fat-3m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 APOBEC1 ALOX5 FERMT3

4.71e-04171944e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASSF6 HSPH1 DUOX2 B3GNT7

4.71e-041719440de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCLO PARD3B RNF39 ZNF416

4.71e-04171944eddc5e05003382603ee49f74b9e2242a43021096
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASSF6 HSPH1 DUOX2 B3GNT7

4.71e-041719440597339618fb4d416d55c538eceb353218a55002
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

DNAH12 DNAH10 MUC16 ALOX15

4.81e-041729446b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTB UHRF1 PRKD1 TNR

4.92e-0417394412f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 TOMM6 PCLO LRP1B

4.92e-0417394466f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 TOMM6 PCLO LRP1B

4.92e-04173944649b08a409095592cccf31883be69c754411280d
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

GRAMD2A PCLO UHRF1 CDC45

5.13e-04175944fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

GRAMD2A PCLO UHRF1 CDC45

5.13e-0417594436c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F CPNE8 GAS2L2 CHGB

5.25e-04176944bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DNAH12 UHRF1 ESPL1 CDC45

5.25e-041769448813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F CPNE8 GAS2L2 CHGB

5.25e-041769443c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN4 RASSF6 PCLO CHGB

5.25e-04176944fb718a6b07aa5d56600263280afa530bcb63db42
ToppCellHealthy-RBC|World / disease group, cell group and cell class

LOXHD1 SPTB TMEM63B LRP1B

5.36e-041779442ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN4 RASSF6 PCLO CHGB

5.59e-04179944f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN4 THEM6 RASSF6 CHGB

5.59e-04179944ec7c38464863ac3744a8d4880f49421914892339
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UHRF1 DOT1L ESPL1 CDC45

5.59e-0417994488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellwk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SPTBN4 PCLO LGI3 CHGB

5.59e-0417994406f92c884189197c86793191c05f65e34925c097
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH12 UHRF1 ESPL1 CDC45

5.59e-04179944e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

MBTD1 CPNE8 DNAH12 DNAH10

5.71e-0418094485fc9b164147b28545e2397d32302eea03ef6346
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A CACNA1F PAXBP1 PPP1R13L

5.83e-04181944b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellIIH-cycling-|IIH / Condition, Cell_class and T cell subcluster

UHRF1 ESPL1 LRP1B CDC45

5.83e-041819447f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCellIIH-cycling|IIH / Condition, Cell_class and T cell subcluster

UHRF1 ESPL1 LRP1B CDC45

5.83e-04181944ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RTN4 HSPH1 TRPV6 CHGB

5.83e-04181944c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
Diseaseulcerative colitis (implicated_via_orthology)

RHOA RHOB RHOC

9.20e-077893DOID:8577 (implicated_via_orthology)
Diseaseperoxisomal biogenesis disorder (implicated_via_orthology)

RHOA RHOB RHOC

1.47e-068893DOID:0080377 (implicated_via_orthology)
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN4 SPTB

5.38e-054892DOID:0050882 (implicated_via_orthology)
Diseasecholangiocarcinoma (is_marker_for)

MUC16 RNF39 ALOX5

9.68e-0464893DOID:4947 (is_marker_for)
Diseaseneurodegenerative disease (implicated_via_orthology)

RHOA RHOB RHOC TRPC1

9.88e-04145894DOID:1289 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

RHOG SLC12A4 LRP1 LRP1B

1.52e-03163894DOID:1826 (implicated_via_orthology)
Diseaseleptin measurement

ARHGAP40 SPTB LRP1B

1.91e-0381893EFO_0005000
Diseaseserum IgM measurement

GRAMD1B PRKD1

2.00e-0322892EFO_0004993
Diseasedescending aortic diameter

SPTBN4 LRP1 DOT1L

2.42e-0388893EFO_0021788
Diseaseeye color

TRANK1 PDCD6 MUC16

2.58e-0390893EFO_0003949
Diseasecerebral amyloid deposition measurement

RHOC PRKD1 PCDH1

3.01e-0395893EFO_0007707

Protein segments in the cluster

PeptideGeneStartEntry
YDEEATWELRVAALG

BTNL3

121

Q6UXE8
EAWVGRDRASYEARE

ARHGEF1

176

Q92888
WEFDVFYDPRELRKE

APOBEC1

21

P41238
TELWSNLEYGRDDVR

TBC1D32

756

Q96NH3
GLAFYDWDNTELIRR

COPB2

446

P35606
LYGRDEFEDLEWSEE

CCDC96

201

Q2M329
YTLERGDFLSEEWRE

DOT1L

216

Q8TEK3
EGYWEELLDTFRPDI

FBXO6

151

Q9NRD1
WSGLEDYFRHLESEL

GRAMD1B

521

Q3KR37
DLDEEYYEEWAERRL

ATP8B2

621

P98198
ADRWYREGLRTLDDL

POLM

251

Q9NP87
DSLFEGTWYLVRVDE

HMGCS1

446

Q01581
LLYSDRDRTFLEGDW

RBM15B

536

Q8NDT2
RWGEFDDLYRISELD

RASSF6

131

Q6ZTQ3
ARESWELLYSLEFLD

INTS10

416

Q9NVR2
FLRDVDWGEVDYLIV

NUBP1

156

P53384
LRGYLDWITQAEELD

CACNA1F

401

O60840
DPEDLGLDRERLYWE

MUC16

12151

Q8WXI7
DDEGRARPSEYDLLW

PARD3B

1046

Q8TEW8
GERYITHESDDLRWE

PRKD1

856

Q15139
IDFDASEERLYWTDI

LRP1B

1611

Q9NZR2
TYVLEELERGIRSWD

MAP1S

31

Q66K74
LWIYLHRDRSEEEFE

NFRKB

646

Q6P4R8
RLVYEESEDRTDDFW

MBTD1

316

Q05BQ5
ERIYWADAREDYIEF

LRP1

3201

Q07954
EWLRQRYDSGEEVDL

FAM13B

71

Q9NYF5
LRLLTETEDWLYEEG

HSPH1

666

Q92598
IGEDDERSKRIWLDY

LOXHD1

1446

Q8IVV2
DQFVRLRDGDRYWFE

DUOX2

506

Q9NRD8
RYRLDFGESQDWVLE

GALNT15

56

Q8N3T1
DSEAYHLRREETDWF

PCLO

4431

Q9Y6V0
LTDIFRRYDTDQDGW

PDCD6

161

O75340
FRDELAYWGIDEARL

KCNG2

101

Q9UJ96
GNLDRERWDSYDLTI

PCDH1

236

Q08174
IDDDLESGYSWRVIL

FBXO48

91

Q5FWF7
DDKAWEYEERDRRSS

NIPBL

1111

Q6KC79
FYDRLINDDDRRWLF

DNAH12

2131

Q6ZR08
ERVRDSWKEDALFGY

ALOX15

216

P16050
FWFGLADIRDSYELV

NAGS

501

Q8N159
LWFESLLFYGCEERE

PAXBP1

651

Q9Y5B6
EDEGNLRFVYELLSW

MACF1

581

Q9UPN3
YEELTGWLREVEEEL

MACF1

5571

Q9UPN3
WGELEGDTYDRVLVD

NSUN4

241

Q96CB9
PTDYDDEEFLRYLWR

HCRTR2

31

O43614
EWEARRRDILFDYEQ

CDC45

176

O75419
LWDVTDRDIDRYTEA

ESPL1

2061

Q14674
DRDIDRYTEALLQGW

ESPL1

2066

Q14674
YDELLEWSDRPLREF

DOCK4

1226

Q8N1I0
DGWTRIRRNEDEEGY

FNBP1

586

Q96RU3
EDLAEWLRDLYGLDI

GAS2L2

36

Q8NHY3
RLEWGEDEESLELIY

FNDC3B

801

Q53EP0
DRTVKIDVYDWDRDG

CPNE9

216

Q8IYJ1
AWDYGRLALVTDADR

TMEM63B

66

Q5T3F8
TEYTAAEEKEDGRRW

BNIP2

116

Q12982
GRYREVRDEDDDWSS

POLR2M

351

P0CAP2
EEEPRSTGELRLWDY

GRAMD2A

296

Q8IUY3
EDRLYGDILQWGFLD

B3GNT7

196

Q8NFL0
LEAREFDWESQLRFY

DNAH10

1761

Q8IVF4
WRLRSGEERQDYSEE

PPP1R18

261

Q6NYC8
DLEWERYRGRGSEEY

CHGB

356

P05060
LWDYSAEFGDELSFR

PPP1R13L

766

Q8WUF5
LFEDWTYDDFRNVLD

CHID1

151

Q9BWS9
DRTIKVEVYDWDRDG

CPNE8

226

Q86YQ8
ALWDTAGQEDYDRLR

RHOC

56

P08134
REEYADFKPFERVWE

RTN4

381

Q9NQC3
ALWDTAGQEDYDRLR

RHOA

56

P61586
ALWDTAGQEDYDRLR

RHOB

56

P62745
TRLLGWDDRAFYLEA

THEM6

121

Q8WUY1
WDDRAFYLEARFVSL

THEM6

126

Q8WUY1
YRDDGLLVWEAIRTF

ALOX5

471

P09917
DRSDYKLGWEIEREL

RNF113B

216

Q8IZP6
WDTAGQEEYDRLRTL

RHOG

56

P84095
NLWRYGDFRADDADE

SND1

891

Q7KZF4
EGLSWVDYGERAELD

SLC12A4

21

Q9UP95
RLWYEGLEDFLEESR

TRPC1

441

P48995
REEELLWYREEGRVD

TMIGD1

61

Q6UXZ0
LERDFYAGLFSWDEV

ARHGAP40

326

Q5TG30
YRALDWGLDESEERE

SPIRE2

106

Q8WWL2
YRFHRARWGLEEEDF

P3H4

336

Q92791
DTWIRLEGLLENTDY

TNR

1091

Q92752
REYGLGDRWFLRVED

TRPV6

661

Q9H1D0
LDWLRDAYRLAAAGD

SPTBN4

786

Q9H254
YIDSSWELRVFVGEE

FERMT3

11

Q86UX7
RFFSYLRSWDVDDLL

TTLL2

326

Q9BWV7
YSDFEWLRSELERES

SNX3

71

O60493
WESLEEAEYRRELAL

SPTB

396

P11277
DWLRGVYRFATDRND

TOMM6

26

Q96B49
SGFLVWRYLLRRDDD

UHRF1

571

Q96T88
FEDVALYLSREEWGR

ZNF205

126

O95201
EDVAVYFSLEEWERL

ZNF316

161

A6NFI3
YFSLEEWERLEADQR

ZNF316

166

A6NFI3
EWGLLDEAQRLLYRD

ZNF416

41

Q9BWM5
RQRGYGWLLEVEDDD

YIPF4

56

Q9BSR8
EEWGLLDEAQRCLYR

ZNF154

26

Q13106
LFERDEEYLMDCDWR

TRANK1

2591

O15050
YADLSDGWLEIIRVD

TCTN2

526

Q96GX1
RVDLDWERGRVAFYD

RNF39

366

Q9H2S5
REDEAWYFFRVERGS

SIGLEC16

111

A6NMB1
DLEAFRIDGDWYFAV

LGI3

331

Q8N145