Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC7A1 SLC7A4 SLC9A4 SLC12A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC44A4 SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

1.23e-1011808724GO:0022857
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 SLC9B2 SLC28A3 SLC44A4 SLC18B1 SLC4A3 SLC3A2 SLC4A2

4.92e-102968713GO:0015291
GeneOntologyMolecularFunctiontransporter activity

SLC7A1 SLC7A4 SLC9A4 SLC12A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC44A4 SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

7.40e-1012898724GO:0005215
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

1.08e-0912875GO:0004706
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 SLC9B2 SLC28A3 SLC44A4 SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

2.06e-094778715GO:0022804
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

3.61e-097588718GO:0015318
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC7A1 SLC7A13 SLCO1C1 SLCO2B1 GRIA3 GRIA4 GRIK3 GRIN2B SLC44A4 SLC4A3 SLC3A2 SLC4A2

5.30e-092938712GO:0008514
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

7.29e-097938718GO:0015075
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC7A1 SLC7A4 SLC7A13 GRIA3 GRIA4 GRIK3 GRIN2B SLC3A2

1.85e-08105878GO:0015171
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 SLC9B2 SLC28A3 SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

7.71e-083018711GO:0022853
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SLC3A2

7.83e-086278715GO:0022890
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

1.05e-0727875GO:0004709
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 KCNQ3 GRIA3 SLC28A3 GRIK3 GRIN2B ATP2B2 ATP2B4 SLC3A2

1.07e-074658713GO:0046873
GeneOntologyMolecularFunctionantiporter activity

SLC9A4 SLC7A13 SLC9B2 SLC44A4 SLC18B1 SLC4A3 SLC3A2 SLC4A2

1.57e-07138878GO:0015297
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC7A1 SLC7A13 SLCO1C1 SLCO2B1 GRIA3 GRIA4 GRIK3 GRIN2B SLC3A2

2.96e-07207879GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC7A1 SLC7A13 SLCO1C1 SLCO2B1 GRIA3 GRIA4 GRIK3 GRIN2B SLC3A2

3.09e-07208879GO:0005342
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA3 GRIA4 GRIK3 GRIN2B

7.66e-0717874GO:0004970
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 KCNQ3 GRIA3 SLC28A3 GRIK3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SLC3A2

1.01e-066648714GO:0008324
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA3 GRIA4 GRIK3 GRIN2B

3.34e-0624874GO:0099507
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA3 GRIA4 GRIK3 GRIN2B

5.46e-0627874GO:0008066
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 SLC9B2 SLC28A3 GRIK3 SLC3A2

9.81e-06171877GO:0015081
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CATSPER4 GRIA3 GRIN2B ATP2B2 ATP2B4 SLC3A2

5.16e-05151876GO:0015085
GeneOntologyMolecularFunctionsodium:potassium:chloride symporter activity

SLC12A1 SLC12A2

5.61e-053872GO:0008511
GeneOntologyMolecularFunctionpotassium:sodium symporter activity

SLC12A1 SLC12A2

5.61e-053872GO:0009674
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA3 GRIA4 GRIK3 GRIN2B

1.11e-0457874GO:1904315
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA3 GRIA4

1.12e-044872GO:0004971
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA3 GRIA4 GRIK3 GRIN2B

1.36e-0460874GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA3 GRIA4 GRIK3 GRIN2B

1.86e-0465874GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA3 GRIA4 GRIK3 GRIN2B

1.86e-0465874GO:0022824
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

2.18e-04125875GO:0015108
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

MST1R UNC5A ADRA1A TIE1 GPR35 RRH OR8S1 GRIA3 GRIA4 S1PR2 GRIK3 GRIN2B TEK ACKR1 IL18RAP AGTRAP

2.19e-0413538716GO:0004888
GeneOntologyMolecularFunctionprotein kinase activity

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

2.79e-046008710GO:0004672
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA3 GRIA4 GRIK3 GRIN2B

3.23e-0475874GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA3 GRIA4 GRIK3 GRIN2B

3.57e-0477874GO:0005230
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIA3 GRIN2B

5.17e-048872GO:0022849
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

5.19e-04151875GO:0008509
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A1 SLC12A2

6.62e-049872GO:0015379
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A4 SLC12A1 SLC12A2 KCNQ3 GRIK3

8.19e-04167875GO:0015079
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A4 SLC9B2 SLC3A2

8.69e-0443873GO:0140828
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

9.11e-04171875GO:0015103
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIA3 GRIA4 GRIK3 GRIN2B

9.59e-04100874GO:0030594
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2B2 ATP2B4

1.01e-0311872GO:0005388
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.02e-037098710GO:0016773
GeneOntologyMolecularFunctionprotein serine kinase activity

AATK RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

1.04e-03363877GO:0106310
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC7A1 SLC3A2

1.42e-0313872GO:0015173
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A3 SLC4A2

1.42e-0313872GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A3 SLC4A2

1.42e-0313872GO:0140829
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

CATSPER4 GRIA3 GRIA4 GRIK3 GRIN2B

1.56e-03193875GO:0015276
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC7A1 SLC44A4

1.65e-0314872GO:1901474
GeneOntologyMolecularFunctionligand-gated channel activity

CATSPER4 GRIA3 GRIA4 GRIK3 GRIN2B

1.71e-03197875GO:0022834
GeneOntologyMolecularFunctionkinase activity

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.78e-037648710GO:0016301
GeneOntologyMolecularFunctionchannel activity

SLC12A2 CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 OCA2 GRIN2B

2.05e-03525878GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A2 CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 OCA2 GRIN2B

2.08e-03526878GO:0022803
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A4 SLC9B2

2.16e-0316872GO:0015385
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC12A1 SLC12A2

2.45e-0317872GO:0015378
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1C1 SLCO2B1

2.74e-0318872GO:0015347
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

MST1R TIE1 TEK

2.87e-0365873GO:0004714
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC12A1 SLC12A2

3.06e-0319872GO:0015373
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

CATSPER4 GRIA3 GRIK3 GRIN2B

3.29e-03140874GO:0099094
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

AATK RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

3.33e-03446877GO:0004674
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A1 SLC7A4

3.39e-0320872GO:0015174
GeneOntologyMolecularFunctiongated channel activity

CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 GRIN2B

3.40e-03334876GO:0022836
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A1 SLC7A13 SLC3A2

3.69e-0371873GO:0015179
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

MST1R AATK TIE1 TEK

3.72e-03145874GO:0004713
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 OCA2 GRIN2B

3.90e-03459877GO:0005216
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A1 SLC12A2

4.47e-0323872GO:0015377
GeneOntologyMolecularFunctionsemaphorin receptor binding

SEMA3E SEMA4C

4.47e-0323872GO:0030215
GeneOntologyMolecularFunctionWW domain binding

NDFIP2 NDFIP1

5.27e-0325872GO:0050699
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC12A1 SLC12A2 SLC28A3

5.34e-0381873GO:0015370
GeneOntologyMolecularFunctiondopamine receptor binding

DNAJC14 GRIN2B

5.70e-0326872GO:0050780
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A1 SLC12A2

5.70e-0326872GO:0015296
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC7A1 SLC44A4 SLC3A2

5.71e-0383873GO:0015101
GeneOntologyMolecularFunctionvirus receptor activity

SLC7A1 CD81 SLC3A2

6.10e-0385873GO:0001618
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

MST1R TIE1 TEK

6.10e-0385873GO:0019199
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A4 SLC9B2

6.14e-0327872GO:0051139
GeneOntologyMolecularFunctionexogenous protein binding

SLC7A1 CD81 SLC3A2

6.30e-0386873GO:0140272
GeneOntologyMolecularFunctionchemorepellent activity

SEMA3E SEMA4C

7.06e-0329872GO:0045499
GeneOntologyMolecularFunctionintegrin binding

CD9 S1PR2 CD81 ITGA2B

7.22e-03175874GO:0005178
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

7.56e-039388710GO:0016772
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIA3 GRIN2B

8.04e-0331872GO:0099604
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A3 SLC4A2

8.55e-0332872GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A3 SLC4A2

8.55e-0332872GO:0005452
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 SLCO1C1 GPR35 SLCO2B1 CATSPER4 SLC9B2 NDFIP2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2 NDFIP1

1.39e-0913748724GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 KCNQ3 GRIA3 GRIA4 SLC28A3 GRIK3 OCA2 GRIN2B SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

2.86e-0811158720GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 KCNQ3 SLC28A3 OCA2 GRIN2B SLC18B1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

9.96e-0710178717GO:0098660
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC7A1 SLC12A2 SLCO1C1 SLCO2B1 SLC4A3 ATP2B4

1.82e-0687876GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC7A1 SLC12A2 SLCO1C1 SLCO2B1 SLC4A3 ATP2B4

1.94e-0688876GO:0010232
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIA3 GRIA4 GRIK3 GRIN2B

4.81e-0627874GO:0035235
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIA3 GRIA4 GRIK3 GRIN2B

9.70e-0632874GO:0099505
GeneOntologyBiologicalProcessmetal ion transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 NDFIP2 KCNQ3 SLC28A3 GRIN2B ATP2B2 ATP2B4 SLC3A2 NDFIP1

1.72e-0510008715GO:0030001
GeneOntologyBiologicalProcesssodium ion transport

SLC9A4 SLC12A1 SLC12A2 CATSPER4 SLC9B2 SLC28A3 ATP2B4 SLC3A2

2.12e-05275878GO:0006814
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 NDFIP2 KCNQ3 SLC28A3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SLC3A2 NDFIP1

2.36e-0511578716GO:0006812
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIA3 GRIA4 GRIK3 GRIN2B

2.40e-0540874GO:1990806
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A4 SLC12A1 SLC12A2 SLC9B2 SLC28A3 ATP2B4 SLC3A2

2.83e-05208877GO:0035725
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 KCNQ3 SLC28A3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SLC3A2

2.98e-059228714GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC9A4 ADRA1A SLC12A1 SLC12A2 GPR35 CATSPER4 SLC9B2 KCNQ3 SLC28A3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SLC3A2

3.76e-059428714GO:0098655
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SLC9A4 SLC12A1 SLC12A2 TMPRSS6 SLC9B2 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

3.93e-057058712GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SLC9A4 SLC12A1 SLC12A2 TMPRSS6 SLC9B2 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

4.63e-057178712GO:0050801
GeneOntologyBiologicalProcessorganic anion transport

SLC7A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 GRIN2B SLC44A4 SLC4A3 SLC3A2 SLC4A2

6.17e-055158710GO:0015711
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC7A1 ADRA1A SLC12A2 SLCO1C1 SLCO2B1 TEK SLC4A3 ATP2B4

1.03e-04344878GO:0003018
GeneOntologyBiologicalProcesstransepithelial ammonium transport

SLC9A4 SLC12A2

1.05e-044872GO:0070634
GeneOntologyBiologicalProcessbasic amino acid transport

SLC7A1 SLC7A4 SLC3A2

1.05e-0422873GO:0015802
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

1.12e-04112875GO:1902476
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIA3 GRIA4 GRIK3 GRIN2B

1.13e-0459874GO:0007215
GeneOntologyBiologicalProcessamino acid transport

SLC7A1 SLC7A4 SLC12A2 SLC7A13 GRIN2B SLC3A2

1.77e-04195876GO:0006865
GeneOntologyBiologicalProcesschloride transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

2.09e-04128875GO:0006821
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

SLC9A4 SLC12A2 TMPRSS6 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

2.49e-046118710GO:0030003
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

2.59e-04134875GO:0098661
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

SLC9A4 SLC12A2 TMPRSS6 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

2.87e-046228710GO:0006873
GeneOntologyBiologicalProcessprotein heterooligomerization

GRIA3 ROM1 GRIN2B

2.99e-0431873GO:0051291
GeneOntologyBiologicalProcessmyoblast fusion involved in skeletal muscle regeneration

CD9 CD81

3.64e-047872GO:0014905
GeneOntologyBiologicalProcessregulation of action potential

ADRA1A GPR35 KCNQ3 SLC4A3

3.84e-0481874GO:0098900
GeneOntologyBiologicalProcessprotein autophosphorylation

AATK MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

4.09e-04228876GO:0046777
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

SLC12A2 CD9 TIE1 WNT2 LEMD2 CD81 ITGA2B NEB SLC44A4 TEK MPIG6B ATP2B2 ATP2B4 SLC4A2 SEMA3E SEMA4C

4.26e-0414838716GO:0048646
GeneOntologyBiologicalProcessimport across plasma membrane

SLC7A1 SLC9A4 SLC12A1 SLC12A2 ATP2B4 SLC3A2

4.29e-04230876GO:0098739
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

4.77e-04153875GO:0098656
GeneOntologyBiologicalProcessMAPK cascade

MST1R ADRA1A LEMD2 MAP3K9 MAP3K10 MAP3K11 CD81 MAP3K13 GRIN2B TEK MAP3K21 SEMA4C

5.17e-049308712GO:0000165
GeneOntologyBiologicalProcessregulation of membrane potential

ADRA1A GPR35 KCNQ3 GRIA3 GRIA4 S1PR2 GRIK3 GRIN2B SLC4A3

5.81e-04559879GO:0042391
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC9A4 OCA2 SLC4A3 SLC4A2

6.74e-0494874GO:0051453
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

SLC12A2 TIE1 WNT2 MAP3K13 TEK SEMA3E

7.83e-04258876GO:0001763
GeneOntologyBiologicalProcesscellular homeostasis

SLC9A4 SLC12A1 SLC12A2 TMPRSS6 SLC9B2 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

8.27e-049818712GO:0019725
GeneOntologyBiologicalProcessdetection of external stimulus

SLC12A2 RRH ROM1 GRIN2B ATP2B2

8.31e-04173875GO:0009581
GeneOntologyBiologicalProcessnegative regulation of angiogenesis

SLC12A2 TIE1 TEK ATP2B4 SEMA3E

8.75e-04175875GO:0016525
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SLC12A2 RRH ROM1 GRIN2B ATP2B2

8.75e-04175875GO:0009582
GeneOntologyBiologicalProcessregulation of cellular pH

SLC9A4 OCA2 SLC4A3 SLC4A2

8.83e-04101874GO:0030641
GeneOntologyBiologicalProcessotolith development

SLC44A4 ATP2B2

9.44e-0411872GO:0048840
GeneOntologyBiologicalProcessmyotube differentiation involved in skeletal muscle regeneration

CD9 CD81

9.44e-0411872GO:0014908
GeneOntologyBiologicalProcessnegative regulation of blood vessel morphogenesis

SLC12A2 TIE1 TEK ATP2B4 SEMA3E

9.44e-04178875GO:2000181
GeneOntologyBiologicalProcessinorganic anion transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

9.93e-04180875GO:0015698
GeneOntologyBiologicalProcessnegative regulation of vasculature development

SLC12A2 TIE1 TEK ATP2B4 SEMA3E

9.93e-04180875GO:1901343
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

GRIA3 GRIA4 S1PR2 GRIK3 GRIN2B

9.93e-04180875GO:0060078
GeneOntologyBiologicalProcessintracellular chemical homeostasis

SLC9A4 SLC12A2 TMPRSS6 SLC9B2 OCA2 GRIN2B ATP2B2 SLC4A3 ATP2B4 SLC4A2 NDFIP1

1.02e-038668711GO:0055082
GeneOntologyBiologicalProcesscirculatory system process

SLC7A1 ADRA1A SLC12A2 SLCO1C1 SLCO2B1 TEK ATP2B2 SLC4A3 ATP2B4 AGTRAP

1.03e-037338710GO:0003013
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC12A1 SLC12A2 OCA2 SLC4A3 SLC4A2

1.07e-03183875GO:0006820
GeneOntologyBiologicalProcesspositive regulation of JUN kinase activity

MAP3K10 MAP3K11 MAP3K13

1.16e-0349873GO:0043507
GeneOntologyBiologicalProcesssodium ion homeostasis

SLC12A1 SLC12A2 SLC9B2

1.30e-0351873GO:0055078
GeneOntologyBiologicalProcessregulation of postsynaptic cytosolic calcium ion concentration

GRIN2B ATP2B2

1.33e-0313872GO:0099566
GeneOntologyBiologicalProcessthyroid hormone transport

SLCO1C1 SLC3A2

1.33e-0313872GO:0070327
GeneOntologyBiologicalProcesssulfur amino acid transport

SLC7A13 SLC3A2

1.33e-0313872GO:0000101
GeneOntologyBiologicalProcessaromatic amino acid transport

SLC7A1 SLC3A2

1.33e-0313872GO:0015801
GeneOntologyCellularComponentapical plasma membrane

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLC7A13 CD9 SLCO2B1 TMEM114 SLC9B2 CD81 SLC44A4 TEK ATP2B2 SLC3A2 SLC4A2

2.41e-094879015GO:0016324
GeneOntologyCellularComponentbasolateral plasma membrane

SLC7A1 SLC9A4 SLC12A2 SLCO1C1 SLCO2B1 SLC9B2 CD81 TEK ATP2B2 ATP2B4 SLC3A2 SLC4A2

1.27e-083209012GO:0016323
GeneOntologyCellularComponentapical part of cell

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLC7A13 CD9 SLCO2B1 TMEM114 SLC9B2 CD81 SLC44A4 TEK ATP2B2 SLC3A2 SLC4A2

3.27e-085929015GO:0045177
GeneOntologyCellularComponentbasal plasma membrane

SLC7A1 SLC9A4 SLC12A2 SLCO1C1 SLCO2B1 SLC9B2 CD81 TEK ATP2B2 ATP2B4 SLC3A2 SLC4A2

3.87e-083549012GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC7A1 SLC9A4 SLC12A2 SLCO1C1 SLCO2B1 SLC9B2 CD81 TEK ATP2B2 ATP2B4 SLC3A2 SLC4A2

7.92e-083789012GO:0045178
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIA3 GRIA4 GRIN2B ATP2B2 ATP2B4

2.18e-0578905GO:0048787
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA3 GRIA4 GRIK3 GRIN2B

4.18e-0545904GO:0008328
GeneOntologyCellularComponentpostsynaptic density membrane

GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 SEMA4C

6.04e-05157906GO:0098839
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA3 GRIA4 GRIK3 GRIN2B

6.36e-0550904GO:0098878
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SLC9A4 SLC12A2 CD9 SLC9B2 HGSNAT NDFIP2 GRIA3 GRIA4 TSPAN14 OCA2 GRIN2B ITGA2B SLC18B1 NDFIP1 AGTRAP SEMA4C

1.32e-0413079016GO:0030659
GeneOntologyCellularComponentvesicle membrane

SLC9A4 SLC12A2 CD9 SLC9B2 HGSNAT NDFIP2 GRIA3 GRIA4 TSPAN14 OCA2 GRIN2B ITGA2B SLC18B1 NDFIP1 AGTRAP SEMA4C

1.54e-0413259016GO:0012506
GeneOntologyCellularComponentpresynaptic membrane

ADRA1A GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 ATP2B4

1.95e-04277907GO:0042734
GeneOntologyCellularComponentreceptor complex

MST1R TRAV2 TIE1 GRIA3 GRIA4 GRIK3 GRIN2B ITGA2B TEK IL18RAP

1.98e-045819010GO:0043235
GeneOntologyCellularComponentpostsynaptic specialization membrane

GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 SEMA4C

2.34e-04201906GO:0099634
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIA4 GRIK3

2.72e-046902GO:0032983
GeneOntologyCellularComponentpresynaptic active zone

GRIA3 GRIA4 GRIN2B ATP2B2 ATP2B4

3.61e-04141905GO:0048786
GeneOntologyCellularComponentplasma membrane protein complex

TRAV2 CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 GRIN2B ITGA2B IL18RAP SSPOP SLC3A2

5.45e-047859011GO:0098797
GeneOntologyCellularComponentterminal bouton

GRIA3 GRIA4 GRIK3 GRIN2B

7.89e-0496904GO:0043195
GeneOntologyCellularComponentplasma membrane signaling receptor complex

TRAV2 GRIA3 GRIA4 GRIK3 GRIN2B ITGA2B IL18RAP

7.90e-04350907GO:0098802
GeneOntologyCellularComponenttetraspanin-enriched microdomain

CD81 TSPAN14

8.07e-0410902GO:0097197
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

GRIA3 GRIN2B ATP2B2

8.41e-0443903GO:0098688
GeneOntologyCellularComponentsperm principal piece

CATSPER4 SLC9B2 ATP2B4

9.00e-0444903GO:0097228
GeneOntologyCellularComponentcell body membrane

UNC5A SLC12A2 ATP2B2

1.09e-0347903GO:0044298
GeneOntologyCellularComponentpresynapse

ADRA1A SLC9B2 GRIA3 GRIA4 S1PR2 GRIK3 GRIN2B SLC18B1 ATP2B2 ATP2B4 SEMA4C

1.46e-038869011GO:0098793
GeneOntologyCellularComponentpostsynaptic membrane

ADRA1A GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 SEMA4C

1.83e-03405907GO:0045211
GeneOntologyCellularComponentplatelet alpha granule membrane

CD9 ITGA2B

2.39e-0317902GO:0031092
GeneOntologyCellularComponentsecretory vesicle

A1BG SLC9A4 CD9 TIMP3 CATSPER4 SLC9B2 HGSNAT TSPAN14 GRIN2B ITGA2B SLC18B1 PGM2 SEMA4C

2.55e-0312469013GO:0099503
GeneOntologyCellularComponentsecretory granule membrane

SLC9A4 CD9 HGSNAT TSPAN14 ITGA2B SLC18B1

2.99e-03329906GO:0030667
GeneOntologyCellularComponentsynaptic membrane

ADRA1A GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 ATP2B4 SEMA4C

3.65e-03583908GO:0097060
GeneOntologyCellularComponentZ disc

ADRA1A GRIN2B NEB ATP2B4

4.13e-03151904GO:0030018
GeneOntologyCellularComponentI band

ADRA1A GRIN2B NEB ATP2B4

5.77e-03166904GO:0031674
GeneOntologyCellularComponentmonoatomic ion channel complex

CATSPER4 KCNQ3 GRIA3 GRIA4 GRIK3 GRIN2B

5.85e-03378906GO:0034702
GeneOntologyCellularComponentsodium channel complex

GRIA4 GRIK3

6.90e-0329902GO:0034706
GeneOntologyCellularComponentAMPA glutamate receptor complex

GRIA3 GRIA4

7.37e-0330902GO:0032281
GeneOntologyCellularComponentplatelet alpha granule

A1BG CD9 ITGA2B

7.58e-0393903GO:0031091
MousePhenovestibular saccular degeneration

SLC12A2 S1PR2 ATP2B2

5.32e-067763MP:0004329
DomainMLK1/MLK2/MLK4

MAP3K9 MAP3K10 MAP3K11 MAP3K21

4.19e-104864IPR016231
DomainMAP3K10

MAP3K9 MAP3K10 MAP3K11 MAP3K21

4.19e-104864IPR015785
DomainTetraspanin

TSPAN17 CD9 TSPAN7 ROM1 CD81 TSPAN14

6.57e-0932866IPR000301
DomainTetraspanin_EC2

TSPAN17 CD9 TSPAN7 ROM1 CD81 TSPAN14

6.57e-0932866IPR008952
DomainTetraspannin

TSPAN17 CD9 TSPAN7 ROM1 CD81 TSPAN14

8.00e-0933866PF00335
DomainTetraspanin/Peripherin

TSPAN17 CD9 TSPAN7 ROM1 CD81 TSPAN14

8.00e-0933866IPR018499
DomainSer-Thr/Tyr_kinase_cat_dom

MST1R AATK TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.43e-08138869IPR001245
DomainTetraspanin_CS

TSPAN17 CD9 TSPAN7 CD81 TSPAN14

3.53e-0821865IPR018503
DomainAA-permease/SLC12A_dom

SLC7A1 SLC7A4 SLC12A1 SLC12A2 SLC7A13

4.56e-0822865IPR004841
DomainAA_permease

SLC7A1 SLC7A4 SLC12A1 SLC12A2 SLC7A13

4.56e-0822865PF00324
DomainTM4_1

TSPAN17 CD9 TSPAN7 CD81 TSPAN14

1.12e-0726865PS00421
DomainPkinase_Tyr

MST1R AATK TIE1 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.41e-07129868PF07714
DomainIontro_rcpt

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864IPR001320
DomainLig_chan-Glu_bd

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864PF10613
DomainIono_rcpt_met

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864IPR001508
DomainGlu/Gly-bd

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864IPR019594
DomainLig_chan-Glu_bd

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864SM00918
DomainLig_chan

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864PF00060
DomainPBPe

GRIA3 GRIA4 GRIK3 GRIN2B

1.22e-0618864SM00079
DomainTyrKc

MST1R TIE1 MAP3K9 MAP3K11 TEK MAP3K21

3.20e-0688866SM00219
DomainTyr_kinase_cat_dom

MST1R TIE1 MAP3K9 MAP3K11 TEK MAP3K21

3.20e-0688866IPR020635
DomainNEDD4/Bsd2

NDFIP2 NDFIP1

2.10e-052862IPR019325
DomainDUF2370

NDFIP2 NDFIP1

2.10e-052862PF10176
DomainNa/K/Cl_cotranspt

SLC12A1 SLC12A2

2.10e-052862IPR002443
DomainANF_lig-bd_rcpt

GRIA3 GRIA4 GRIK3 GRIN2B

2.46e-0537864IPR001828
DomainANF_receptor

GRIA3 GRIA4 GRIK3 GRIN2B

2.46e-0537864PF01094
DomainAA_permease_2

SLC7A1 SLC7A4 SLC7A13

2.61e-0513863PF13520
DomainAA/rel_permease1

SLC7A1 SLC7A4 SLC7A13

2.61e-0513863IPR002293
DomainSH3_9

MAP3K9 MAP3K10 MAP3K11 NEB MAP3K21

2.98e-0578865PF14604
DomainPeripla_BP_I

GRIA3 GRIA4 GRIK3 GRIN2B

3.05e-0539864IPR028082
DomainPROTEIN_KINASE_ATP

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

4.86e-054598610PS00107
DomainProtein_kinase_ATP_BS

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 TEK MAP3K21

6.16e-05379869IPR017441
DomainAA_permease_N

SLC12A1 SLC12A2

6.27e-053862IPR013612
DomainAnion_exchange_CS

SLC4A3 SLC4A2

6.27e-053862IPR018241
DomainAA_permease_N

SLC12A1 SLC12A2

6.27e-053862PF08403
DomainProt_kinase_dom

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

8.24e-054898610IPR000719
DomainPROTEIN_KINASE_DOM

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

8.81e-054938610PS50011
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

1.25e-044862IPR022141
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

1.25e-044862PF12424
DomainP-type_ATPase_IIB

ATP2B2 ATP2B4

1.25e-044862IPR006408
DomainKinase-like_dom

MST1R AATK RPS6KA4 TIE1 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.91e-045428610IPR011009
DomainCAT3

SLC7A1 SLC7A4

2.08e-045862IPR015606
DomainAA_permease_C

SLC7A1 SLC7A4

2.08e-045862PF13906
DomainAnion_exchange

SLC4A3 SLC4A2

2.08e-045862IPR001717
DomainCAT_C

SLC7A1 SLC7A4

2.08e-045862IPR029485
Domain-

CD9 CD81

2.08e-0458621.10.1450.10
DomainCD81_LEL

CD9 CD81

2.08e-045862IPR028977
DomainSema

MST1R SEMA3E SEMA4C

3.86e-0431863SM00630
DomainSemap_dom

MST1R SEMA3E SEMA4C

3.86e-0431863IPR001627
DomainSema

MST1R SEMA3E SEMA4C

3.86e-0431863PF01403
DomainSEMA

MST1R SEMA3E SEMA4C

3.86e-0431863PS51004
DomainSLC12A_fam

SLC12A1 SLC12A2

4.34e-047862IPR004842
DomainANION_EXCHANGER_2

SLC4A3 SLC4A2

4.34e-047862PS00220
DomainANION_EXCHANGER_1

SLC4A3 SLC4A2

4.34e-047862PS00219
DomainSLC12_C

SLC12A1 SLC12A2

5.76e-048862IPR018491
DomainSLC12

SLC12A1 SLC12A2

5.76e-048862PF03522
DomainBand3_cytoplasmic_dom

SLC4A3 SLC4A2

7.39e-049862IPR013769
DomainClaudin_2

TMEM114 TMEM178B

7.39e-049862PF13903
DomainBand_3_cyto

SLC4A3 SLC4A2

7.39e-049862PF07565
Domain-

SLC4A3 SLC4A2

7.39e-0498623.40.1100.10
DomainHCO3_cotransp

SLC4A3 SLC4A2

9.21e-0410862PF00955
DomainHCO3_transpt_C

SLC4A3 SLC4A2

9.21e-0410862IPR011531
DomainPTrfase/Anion_transptr

SLC4A3 SLC4A2

9.21e-0410862IPR016152
DomainHCO3_transpt_euk

SLC4A3 SLC4A2

9.21e-0410862IPR003020
DomainPROTEIN_KINASE_TYR

MST1R AATK TIE1 TEK

1.05e-0397864PS00109
DomainTyr_kinase_AS

MST1R AATK TIE1 TEK

1.05e-0397864IPR008266
DomainPSI

MST1R SEMA3E SEMA4C

1.09e-0344863IPR016201
DomainPSI

MST1R SEMA3E SEMA4C

1.24e-0346863SM00423
DomainS_TKc

RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13 TEK MAP3K21

1.34e-03359867SM00220
DomainOA_transporter

SLCO1C1 SLCO2B1

1.34e-0312862IPR004156
DomainOATP

SLCO1C1 SLCO2B1

1.34e-0312862PF03137
DomainNa_H_Exchanger

SLC9A4 SLC9B2

1.84e-0314862PF00999
DomainCation/H_exchanger

SLC9A4 SLC9B2

1.84e-0314862IPR006153
Domain-

ATP2B2 ATP2B4

2.41e-03168621.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2B2 ATP2B4

2.41e-0316862IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP2B2 ATP2B4

2.72e-0317862IPR006068
DomainCation_ATPase_C

ATP2B2 ATP2B4

2.72e-0317862PF00689
DomainCation_ATPase_N

ATP2B2 ATP2B4

3.06e-0318862PF00690
DomainCation_ATPase_N

ATP2B2 ATP2B4

3.06e-0318862SM00831
DomainSH3

MAP3K9 MAP3K10 MAP3K11 NEB MAP3K21

3.22e-03216865SM00326
DomainSH3

MAP3K9 MAP3K10 MAP3K11 NEB MAP3K21

3.22e-03216865PS50002
DomainIG

A1BG UNC5A TIE1 MPIG6B IL18RAP SEMA3E SEMA4C

3.28e-03421867SM00409
DomainIg_sub

A1BG UNC5A TIE1 MPIG6B IL18RAP SEMA3E SEMA4C

3.28e-03421867IPR003599
DomainATPase_P-typ_cation-transptr_N

ATP2B2 ATP2B4

3.41e-0319862IPR004014
DomainSH3_domain

MAP3K9 MAP3K10 MAP3K11 NEB MAP3K21

3.48e-03220865IPR001452
DomainSemaphorin

SEMA3E SEMA4C

3.77e-0320862IPR027231
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

1.73e-0912685M47929
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLCO1C1 SLCO2B1 SLC28A3 SLC44A4 SLC4A3 SLC3A2 SLC4A2

1.66e-082386811MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLCO1C1 SLCO2B1 SLC28A3 SLC44A4 SLC4A3 SLC3A2 SLC4A2

2.64e-082496811M5988
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLC4A3 SLC3A2 SLC4A2

8.41e-07108687M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLC4A3 SLC3A2 SLC4A2

8.95e-07109687MM15074
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLCO1C1 SLCO2B1 SLC9B2 SLC28A3 SLC44A4 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

3.60e-066816814MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC7A1 SLC9A4 SLC12A1 SLC12A2 SLCO1C1 SLCO2B1 SLC9B2 SLC28A3 SLC44A4 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

8.79e-067366814M27287
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

KCNQ3 GRIN2B ATP2B2 ATP2B4

2.60e-0536684M39831
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

RPS6KA4 SLCO1C1 MAP3K9 MAP3K10 MAP3K11 MAP3K13

4.09e-05132686M39338
PathwayBIOCARTA_MAPK_PATHWAY

RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13

4.34e-0581685M13863
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

TSPAN7 GRIA3 GRIA4

5.75e-0516683MM15048
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

TSPAN7 GRIA3 GRIA4

6.96e-0517683M5488
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA3 GRIA4 GRIN2B

8.32e-0518683M48098
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA3 GRIA4 GRIN2B

1.34e-0421683M27736
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA3 GRIA4 GRIN2B

1.34e-0421683M838
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

GRIA3 GRIA4 ATP2B2

1.55e-0422683M39795
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADRA1A GPR35 GRIA3 GRIA4 S1PR2 GRIK3 GRIN2B

3.27e-04272687M13380
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

TSPAN7 GRIA3 GRIA4

3.59e-0429683MM15028
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

TSPAN7 GRIA3 GRIA4

4.38e-0431683M7223
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A1 SLC12A2

4.74e-047682M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A1 SLC12A2

4.74e-047682MM15081
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAP3K9 MAP3K10 MAP3K11

6.84e-0436683M39908
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO1C1 SLCO2B1 SLC28A3

1.00e-0341683MM15075
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A3 SLC4A2

1.01e-0310682M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A3 SLC4A2

1.01e-0310682MM15073
PathwayWP_INSULIN_SIGNALING

RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13

1.04e-03160685M39482
PathwayWP_INSULIN_SIGNALING

RPS6KA4 MAP3K9 MAP3K10 MAP3K11 MAP3K13

1.04e-03160685MM15956
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO1C1 SLCO2B1 SLC28A3

1.15e-0343683M881
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLCO2B1

1.23e-0311682M930
PathwayREACTOME_HEMOSTASIS

A1BG CD9 TIMP3 TSPAN7 ITGA2B TEK MPIG6B ATP2B2 ATP2B4 SLC3A2

1.46e-036796810M8395
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B2 ATP2B4

1.47e-0312682M27326
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLCO2B1

1.47e-0312682MM15476
PathwayREACTOME_HEMOSTASIS

A1BG CD9 TIMP3 ITGA2B TEK MPIG6B ATP2B2 ATP2B4 SLC3A2

1.61e-03571689MM14472
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B2 ATP2B4

2.01e-0314682MM15052
Pubmed

TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals.

TSPAN17 CD9 CD81 TSPAN14

8.31e-091089423091066
Pubmed

Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.

MAP3K9 MAP3K10 MAP3K11

1.62e-0838938195146
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA3 GRIA4 GRIK3 GRIN2B

2.81e-081389420859245
Pubmed

MAP3Ks as central regulators of cell fate during development.

MAP3K9 MAP3K10 MAP3K11 MAP3K13

5.35e-081589418855897
Pubmed

Strategies for targeting tetraspanin proteins: potential therapeutic applications in microbial infections.

CD9 TSPAN7 CD81

6.47e-08489319894777
Pubmed

Modulation of human immunodeficiency virus type 1 infectivity through incorporation of tetraspanin proteins.

CD9 TSPAN7 CD81

1.61e-07589317989173
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ADRA1A AATK DNAJC14 TMEM42 GPR35 TSPAN7 RETREG1 CD81 SLC18B1 SLC4A3 SLC3A2 NDFIP1

2.22e-07697891228298427
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC7A1 SLC12A2 SLCO1C1 SLCO2B1 SLC4A3 ATP2B4

3.11e-0710589630280653
Pubmed

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.

GRIA4 GRIK3 GRIN2B

3.22e-07689318922769
Pubmed

Exosomal-like vesicles are present in human blood plasma.

CD9 CD81 ITGA2B

3.22e-07689315908444
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA3 GRIA4 GRIK3 GRIN2B

4.09e-072489435746896
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA3 GRIA4 GRIK3

5.63e-0778939016303
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA3 GRIA4 GRIK3

5.63e-0778939651535
Pubmed

TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.

CD9 CD81 TSPAN14

8.99e-07889326686862
Pubmed

Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation.

SLC12A2 SLC4A3 SLC4A2

8.99e-07889326110920
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIA4 GRIK3 GRIN2B

8.99e-0788938163463
Pubmed

Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.

MAP3K9 MAP3K10 MAP3K11

1.35e-06989314504284
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA3 GRIA4 GRIK3

1.35e-0698939051806
Pubmed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

MST1R IFIH1 FADS1 RPS6KA4 GPR35 TSPAN14 IL18RAP NDFIP1

2.85e-0634289823128233
Pubmed

Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions.

CD9 TSPAN7 CD81

3.50e-061289310229664
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

KCNQ3 GRIA3 GRIA4 GRIN2B

5.51e-064589425979088
Pubmed

Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.

TIE1 ITGA2B TEK

5.78e-061489310981960
Pubmed

Tie-1: A potential target for anti-angiogenesis therapy.

TIE1 TEK

6.48e-06289226489611
Pubmed

Multisensory plasticity in congenitally deaf mice: how are cortical areas functionally specified?

SLC12A2 ATP2B2

6.48e-06289216529873
Pubmed

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity.

CD9 CD81

6.48e-06289212483205
Pubmed

CD81 interacts with the T cell receptor to suppress signaling.

CD9 CD81

6.48e-06289223226274
Pubmed

NKCC1-dependent GABAergic excitation drives synaptic network maturation during early hippocampal development.

SLC12A2 SLC4A3

6.48e-06289219295148
Pubmed

Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.

GRIA3 GRIA4

6.48e-06289212670305
Pubmed

Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger.

SLC9A4 SLC4A2

6.48e-06289215684419
Pubmed

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.

GRIA3 GRIA4

6.48e-0628927992055
Pubmed

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

TIE1 TEK

6.48e-06289210995770
Pubmed

Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.

TIE1 TEK

6.48e-0628928395828
Pubmed

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.

MAP3K9 MAP3K10

6.48e-06289211416147
Pubmed

Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization.

SLC4A3 SLC4A2

6.48e-06289211248201
Pubmed

CD9 and CD81 Interactions and Their Structural Modelling in Sperm Prior to Fertilization.

CD9 CD81

6.48e-06289229671763
Pubmed

Elimination of redundant synaptic inputs in the absence of synaptic strengthening.

GRIA3 GRIA4

6.48e-06289222090494
Pubmed

Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs.

TIE1 TEK

6.48e-06289215893943
Pubmed

Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients.

CD9 CD81

6.48e-06289236826611
Pubmed

Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells.

SLC12A1 SLC12A2

6.48e-0628927929272
Pubmed

Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.

MAP3K9 MAP3K10

6.48e-0628928477742
Pubmed

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

TIE1 TEK

6.48e-0628928846781
Pubmed

Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.

MAP3K9 MAP3K10

6.48e-0628928536694
Pubmed

CD81 and CD9 work independently as extracellular components upon fusion of sperm and oocyte.

CD9 CD81

6.48e-06289223213457
Pubmed

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

TIE1 TEK

6.48e-0628921312667
Pubmed

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2.

SLC12A1 SLC12A2

6.48e-0628928640224
Pubmed

Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.

TIE1 TEK

6.48e-06289217504972
Pubmed

Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.

CD9 CD81

6.48e-06289229572511
Pubmed

Infertility of CD9-deficient mouse eggs is reversed by mouse CD9, human CD9, or mouse CD81; polyadenylated mRNA injection developed for molecular analysis of sperm-egg fusion.

CD9 CD81

6.48e-06289212086470
Pubmed

The Na-K-Cl cotransporters.

SLC12A1 SLC12A2

6.48e-0628929672238
Pubmed

Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.

ATP2B2 ATP2B4

6.48e-0628921313367
Pubmed

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.

GRIA3 GRIA4

6.48e-06289218316356
Pubmed

Association of SLC12A1 and GLUR4 Ion Transporters with Neoadjuvant Chemoresistance in Luminal Locally Advanced Breast Cancer.

SLC12A1 GRIA4

6.48e-06289238003293
Pubmed

Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.

SLC12A2 SLC4A3

6.48e-06289218779325
Pubmed

Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro.

CD9 CD81

6.48e-06289223223239
Pubmed

Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.

ATP2B2 ATP2B4

6.48e-06289222252018
Pubmed

Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.

SLC12A1 SLC12A2

6.48e-06289216814616
Pubmed

Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis.

TIE1 TEK

6.48e-06289214530387
Pubmed

Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.

TIE1 TEK

6.48e-06289220227369
Pubmed

Tetraspanin blockage reduces exosome-mediated HIV-1 entry.

CD9 CD81

6.48e-06289229429034
Pubmed

Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.

ATP2B2 ATP2B4

6.48e-06289225690014
Pubmed

Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues.

TIE1 TEK

6.48e-0628929108247
Pubmed

Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity.

MAP3K10 MAP3K11

6.48e-06289223954791
Pubmed

Double deficiency of tetraspanins CD9 and CD81 alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice.

CD9 CD81

6.48e-06289218662991
Pubmed

An alternate pathway of cAMP-stimulated Cl secretion across the NKCC1-null murine duodenum.

SLC12A2 SLC4A2

6.48e-06289212145806
Pubmed

Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.

CD9 CD81

6.48e-06289220124223
Pubmed

Reduced fertility of female mice lacking CD81.

CD9 CD81

6.48e-06289216380109
Pubmed

Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice.

SLC12A1 SLC12A2

6.48e-06289226400961
Pubmed

cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.

SLC4A3 SLC4A2

6.48e-0628922294114
Pubmed

GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.

GRIA3 GRIA4

6.48e-06289221690196
Pubmed

Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.

ATP2B2 ATP2B4

6.48e-06289216216224
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIA3 GRIA4 GRIN2B

7.21e-06158939481670
Pubmed

JunB is essential for mammalian placentation.

TIE1 TIMP3 TEK

7.21e-061589310022836
Pubmed

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.

MGAT1 SLC12A2 CD9 GRIA4

8.43e-065089424769233
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC7A1 CD81 SLC3A2

1.29e-051889331791063
Pubmed

Spry1 is expressed in hemangioblasts and negatively regulates primitive hematopoiesis and endothelial cell function.

TIE1 ITGA2B TEK

1.29e-051889321483770
Pubmed

Appearance of new tetraspanin genes during vertebrate evolution.

TSPAN17 TSPAN7 TSPAN14

1.79e-052089318291621
Pubmed

Lateral organization of membrane proteins: tetraspanins spin their web.

CD9 CD81

1.94e-05389219426143
Pubmed

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.

S1PR2 ITGA2B

1.94e-05389223148237
Pubmed

A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions.

TIE1 TEK

1.94e-05389232822567
Pubmed

The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells.

GRIA3 GRIA4

1.94e-05389228397107
Pubmed

Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.

MAP3K9 MAP3K10

1.94e-05389218414056
Pubmed

Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4.

SLC7A1 SLC7A4

1.94e-05389211665818
Pubmed

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.

TIE1 TEK

1.94e-05389226344773
Pubmed

Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains.

CD9 CD81

1.94e-05389217522207
Pubmed

Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells.

TIE1 TEK

1.94e-05389222342979
Pubmed

Expression and function of bicarbonate/chloride exchangers in the preimplantation mouse embryo.

SLC4A3 SLC4A2

1.94e-0538927592657
Pubmed

CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages.

CD9 CD81

1.94e-05389218321974
Pubmed

Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice.

MST1R PGM2

1.94e-0538926283161
Pubmed

Tetraspanins CD9 and CD81 are molecular partners of trimeric FcɛRI on human antigen-presenting cells.

CD9 CD81

1.94e-05389221241315
Pubmed

Integrating disease and drug-related phenotypes for improved identification of pharmacogenomic variants.

SLC9A4 IL18RAP

1.94e-05389233769074
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA3 GRIA4

1.94e-05389218163426
Pubmed

Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.

SLC12A1 SLC12A2

1.94e-0538928663127
Pubmed

Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex.

TIE1 TEK

1.94e-05389211866538
Pubmed

Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.

GRIA3 GRIA4

1.94e-05389212172541
Pubmed

Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.

SLC4A3 SLC4A2

1.94e-05389211208611
Pubmed

Gag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane.

CD9 CD81

1.94e-05389221813604
Pubmed

Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems.

TIE1 TEK

1.94e-05389227941161
Pubmed

Tetraspanins CD9 and CD81 modulate HIV-1-induced membrane fusion.

CD9 CD81

1.94e-05389217015697
Pubmed

Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1.

TIE1 TEK

1.94e-05389223504320
Pubmed

Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

TIE1 TEK

1.94e-05389217728252
InteractionLGALS9C interactions

SLC7A1 SLC12A2 ATP2B4 SLC4A2

1.53e-0535874int:LGALS9C
InteractionSLC11A2 interactions

TVP23C NDFIP2 ATP2B4 NDFIP1

2.14e-0538874int:SLC11A2
InteractionDLG3 interactions

RPS6KA4 GRIN2B CNPY2 ATP2B2 ATP2B4 SEMA4C

2.21e-05131876int:DLG3
InteractionMS4A15 interactions

FADS1 SLC12A2 ATP2B4 SLC4A2

2.37e-0539874int:MS4A15
InteractionHCRTR2 interactions

FADS1 TVP23C ATP2B2 ATP2B4

2.37e-0539874int:HCRTR2
InteractionHPCA interactions

MAP3K9 MAP3K10 MAP3K11 MAP3K21

3.85e-0544874int:HPCA
InteractionHPCAL1 interactions

MAP3K9 MAP3K10 MAP3K11 S1PR2 MAP3K21

3.95e-0588875int:HPCAL1
InteractionTTYH1 interactions

FADS1 SLC12A2 LEMD2 TVP23C S1PR2 ATP2B2 ATP2B4 SLC4A2

4.63e-05300878int:TTYH1
InteractionCMKLR1 interactions

FADS1 LEMD2 TVP23C ATP2B2 ATP2B4

7.64e-05101875int:CMKLR1
InteractionENTPD7 interactions

ATP2B2 ATP2B4 TMEM181 NDFIP1

8.07e-0553874int:ENTPD7
InteractionHTR3A interactions

SLC12A2 LEMD2 OCA2 ATP2B2 ATP2B4

1.05e-04108875int:HTR3A
InteractionRNF149 interactions

SLC7A1 TSPAN17 SLC12A2 LEMD2 NDFIP2 ATP2B4 SLC3A2 SLC4A2 NDFIP1 SEMA4C

1.26e-045498710int:RNF149
InteractionPTGFR interactions

NDFIP2 ATP2B2 NDFIP1

1.29e-0423873int:PTGFR
InteractionDLG4 interactions

SLCO1C1 MAP3K10 MAP3K11 GRIA3 GRIA4 GRIN2B ATP2B2 ATP2B4 SEMA4C

1.38e-04449879int:DLG4
InteractionTSPAN15 interactions

SLC7A1 FADS1 LEMD2 TVP23C S1PR2 TMEM181 SLC4A2

1.92e-04276877int:TSPAN15
Cytoband11q13

SLCO2B1 ROM1 SLC3A2

1.65e-0311890311q13
Cytoband22q12.3

TIMP3 TMPRSS6

1.93e-033390222q12.3
GeneFamilySolute carriers

SLC7A1 SLC7A4 SLC9A4 SLC12A1 SLC12A2 SLC7A13 SLCO1C1 SLCO2B1 SLC9B2 SLC28A3 SLC44A4 SLC18B1 SLC4A3 SLC3A2 SLC4A2

1.16e-113956715752
GeneFamilyCD molecules|Tetraspanins

TSPAN17 CD9 TSPAN7 ROM1 CD81 TSPAN14

2.11e-0933676768
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K9 MAP3K10 MAP3K11 MAP3K13 MAP3K21

2.42e-0824675654
GeneFamilyReceptor Tyrosine Kinases|CD molecules

MST1R AATK TIE1 TEK

1.42e-0540674321
GeneFamilyImmunoglobulin like domain containing

A1BG TIE1 TEK IL18RAP SEMA3E SEMA4C

7.95e-05193676594
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA3 GRIA4

8.08e-0546721200
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MST1R CD9 TSPAN7 CD81 ITGA2B TEK ACKR1 IL18RAP

1.01e-04394678471
GeneFamilyATPases Ca2+ transporting

ATP2B2 ATP2B4

4.79e-0496721209
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3E SEMA4C

2.46e-0320672736
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

TSPAN7 RETREG1 MAP3K9 MAP3K11 KCNQ3 GRIA3 GRIA4 GRIK3 NEB TMEM178B ATP2B2 SLC4A3 SEMA3E

1.88e-085069013M39067
CoexpressionGSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN

IFIH1 FADS1 RPS6KA4 LEMD2 ROM1 IL18RAP SIT1 SLC3A2

4.53e-07200908M8533
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HSERT

AATK TSPAN7 RETREG1 KCNQ3 GRIA4 TMEM178B PIGZ ATP2B2 SLC4A3 NDFIP1

3.38e-064509010M39072
CoexpressionGSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN

IFIH1 TIE1 CD81 PGLYRP2 ITGA2B SLC18B1 ATP2B4

5.55e-06198907M7480
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AATK TSPAN7 RETREG1 MAP3K9 TVP23C KCNQ3 GRIA4 GRIK3 NEB TMEM178B SSPOP ATP2B2 SLC4A3 SEMA3E

2.37e-0511069014M39071
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

IFIH1 SLC12A2 TIE1 TIMP3 SLC9B2 RETREG1 GRIA3 PGLYRP2 TEK SLC3A2 SEMA3E

3.66e-057219011M1999
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN

TSPAN17 SLC9B2 NEB IL18RAP ATP2B4 NDFIP1

6.69e-05200906M7958
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

TIE1 TIMP3 SLCO2B1 TSPAN7 TEK

3.44e-0590875GSM777032_100
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

TIE1 TIMP3 SLCO2B1 TSPAN7 TEK

3.44e-0590875GSM777037_100
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

TIE1 TIMP3 CYP4B1 TSPAN7 TEK

3.62e-0591875GSM777059_100
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

TIE1 TIMP3 CYP4B1 TSPAN7 TEK

4.69e-0596875GSM777063_100
CoexpressionAtlascerebral cortex

UNC5A AATK SLCO1C1 SLC9B2 TSPAN7 MAP3K10 PCDHA11 KCNQ3 GRIA3 GRIA4 ROM1 PCDHA1 GRIK3 GRIN2B TMEM178B ATP2B2 SLC4A3

5.87e-0514288717cerebral cortex
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1 ATP2B4

5.69e-091939088084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1 ATP2B4

6.17e-09195908126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1 SLC3A2

7.64e-08178907ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1 SLC3A2

7.64e-08178907ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1 SLC3A2

7.64e-0817890787b04753650e45f12299c8456fb980d6c0d5961c
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.11e-071889070aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.19e-07190907a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.19e-0719090725525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.28e-071929075890076929598e88fe9d59a4e4e858b446746ce9
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.33e-071939074a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.33e-07193907d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.37e-07194907db7b0c77ad88f7b74d85679f1fb8ee7140ac3f62
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.37e-0719490717d530982789acc5e6889b215f3d433d138a41c4
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.37e-071949075992b9409d5855eff2afc3acd201ccd25420d2e0
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.42e-07195907f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.42e-07195907ea1b00805391dca8be0883b635768b296369919a
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.42e-071959070c15be3e7c238e329505dcbbe197a977d1019d45
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.42e-0719590785df110f753f58ab017018c54ee454edb4428e29
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.42e-0719590745ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 TSPAN7 CD81 TEK ACKR1

1.42e-071959075b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.52e-07197907deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.52e-07197907d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.52e-07197907a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ATP2B4

1.52e-07197907412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK ACKR1

1.58e-07198907f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

MST1R UNC5A SLC7A13 PCDHA11 GRIA3 PIGZ

3.76e-0713890605de2cef97c0912fb23f138dd45348f565a14d74
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD9 TIE1 TIMP3 TSPAN7 PCDHA11 GRIN2B

1.28e-061709064848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCelldroplet-Fat-Scat-21m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS35 TIE1 TIMP3 CYP4B1 TSPAN7 NEB

1.41e-06173906f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCellfacs-Lung-Endomucin-24m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

1.46e-06174906ea27868d0373843a5137569ac3f9e3f8c92c7dcc
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

1.51e-061759061c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

UNC5A TIE1 TIMP3 TSPAN7 TEK ACKR1

1.61e-0617790671bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 TIMP3 CD81 ACKR1 ATP2B2 ATP2B4

1.61e-061779066f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

1.72e-061799069968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A1 CD9 TIE1 TIMP3 TSPAN7 TSPAN14

1.72e-061799061c0c0647a111f691dae55f4ed8c51006059ce020
ToppCellfacs-GAT-Fat-18m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1BG TIE1 TIMP3 CYP4B1 TSPAN7 TEK

1.72e-06179906d56fa2a0b119d51a8d41b00fbbd7dfddefeb279c
ToppCellfacs-GAT-Fat-18m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1BG TIE1 TIMP3 CYP4B1 TSPAN7 TEK

1.72e-06179906e0542694fa79d67f67be6f85b4fa6d18f7523253
ToppCellfacs-GAT-Fat-18m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1BG TIE1 TIMP3 CYP4B1 TSPAN7 TEK

1.72e-0617990683343b68977969c7978acd930a66fc7c44df6a15
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 ACKR1 SLC3A2

1.78e-06180906178648429686e6d4e6f3aafc350130e819788ecf
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 TIE1 CYP4B1 TSPAN7 TEK ATP2B4

1.78e-06180906174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 CYP4B1 WNT2 ITGA2B ACKR1 SEMA3E

1.78e-061809066c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

SLCO1C1 CD9 TIMP3 NDFIP2 GRIA4 ITGA2B

1.78e-06180906b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 ACKR1 SLC3A2

1.78e-06180906fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 ACKR1 SLC3A2

1.78e-06180906c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1

1.84e-0618190672c28baf4fd417ff4a7068603830d55074960144
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1

1.84e-061819062ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TSPAN7 CD81 TEK ACKR1

1.84e-061819062628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellP28-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

1.89e-06182906db5d6c5e7d59734653906b126f2c1d57461a5290
ToppCellP28-Endothelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

2.02e-06184906b056411f499866097f4322999cfd1e57a3927b78
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.02e-0618490644d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP3 CYP4B1 TSPAN7 TEK ACKR1 ATP2B4

2.08e-06185906742350093d90f96735dc73e3360cdd749bae63fd
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UNC5A CD9 TIE1 TIMP3 TSPAN7 ITGA2B

2.08e-06185906d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCellP28-Endothelial-capillary_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

2.15e-0618690626a625ca0300055d6af3472aa0bfba59b73db292
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ATP2B4

2.15e-061869062cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ATP2B4

2.15e-0618690690d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 SLCO2B1 TSPAN7 TEK ACKR1

2.22e-061879063548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.22e-061879062d20193a6cacdfa4877457c97b0077408942186c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 SLCO2B1 TSPAN7 TEK ACKR1

2.22e-06187906f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 SLCO2B1 TSPAN7 TEK ACKR1

2.22e-0618790681754e965848b718be20ee97ce072ce426938a69
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD9 TIE1 SLCO2B1 TSPAN7 MAP3K11 TEK

2.29e-06188906b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 SLCO2B1 TSPAN7 TEK

2.29e-0618890605de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCelldroplet-Fat-SCAT-30m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 TIMP3 CD81 TEK ACKR1 SEMA3E

2.36e-061899068161910a19089f8cc5a3f1fda039f41a2488f04f
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

TIE1 TIMP3 CYP4B1 SLCO2B1 TSPAN7 TEK

2.36e-061899069a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.36e-061899060f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 SLCO2B1 TSPAN7 TEK

2.36e-061899068ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 SLCO2B1 TSPAN7 TEK

2.36e-06189906403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCelldroplet-Fat-SCAT|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 TIMP3 CD81 TEK ACKR1 SEMA3E

2.36e-06189906264c59de2adb8bee5bb57633d79d530a8829617b
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.43e-061909066b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.43e-06190906ff083168d609957d00888f31b3488d6d56c902b4
ToppCellfacs-BAT-Fat-18m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 CD81 TEK

2.58e-061929063a99c521c599a289ee2309d97be5ceb99f8aa220
ToppCellfacs-Thymus-Epithelium-24m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.58e-0619290639afea574725ce0c67afdd79facdb34f819a828d
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 CYP4B1 SLCO2B1 TSPAN7 TEK ACKR1

2.58e-06192906945153c41dde6e90d103206955e1707b54eb0665
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A1 SLCO1C1 TIE1 TIMP3 SLCO2B1 TEK

2.58e-061929069d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCellfacs-BAT-Fat-18m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 CD81 TEK

2.58e-06192906f9777e0fdd86c2a514f05a42502888329a94b396
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.58e-06192906597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.58e-06192906bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 CYP4B1 SLCO2B1 TSPAN7 TEK ACKR1

2.58e-061929066ab50579c63f31ca2cd41063a99b129f11c07510
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.58e-061929062bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-BAT-Fat-18m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 TSPAN7 CD81 TEK

2.58e-06192906562e15876088af9189744c9b2de5c4863d7f15fd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A1 SLCO1C1 TIE1 TIMP3 SLCO2B1 TEK

2.58e-06192906042391162df2e3d0027688dd14163c4c6821afe0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A1 SLCO1C1 TIE1 TIMP3 SLCO2B1 TEK

2.58e-0619290671b0bfee0461ff64cef35881db3959c517e9731b
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.58e-06192906e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.58e-06192906d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 CYP4B1 TSPAN7 TEK SLC3A2

2.58e-06192906517bc24b9ad5e2b5a3609ca55d7327c4700db9db
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.66e-06193906826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.66e-0619390687d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CD9 TIE1 SLCO2B1 TSPAN7 MAP3K11 TEK

2.66e-06193906643f992dbce639e7d147924d8b8f455fcebf215a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.66e-06193906d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 TIMP3 CYP4B1 WNT2 TSPAN7 TEK

2.74e-06194906c8b9551b93a5aed62154b487db90130604a6125c
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.74e-061949062e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCelldroplet-Lung-21m-Endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 CYP4B1 TSPAN7 TEK

2.74e-06194906b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCellEndothelial-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.74e-06194906abea887dd472c1a0d572e690bc8914c1b94712ad
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.74e-06194906b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCellHSPCs-Mk_prog.|HSPCs / Lineage and Cell class

CD9 TIE1 TIMP3 CD81 ITGA2B TEK

2.74e-061949065c05d508f5c29e6efe87506bf59e3b0fe5922f65
ToppCelldroplet-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 TIE1 TIMP3 CYP4B1 TSPAN7 TEK

2.74e-06194906fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.82e-06195906e8ab3122f81cb22920becd6611cbd9f00db19d50
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 CYP4B1 SLCO2B1 TSPAN7 TEK ACKR1

2.82e-061959064db30b3bc65c25626f828cd4f867f20c71809898
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TIE1 TIMP3 TSPAN7 TMEM178B TEK ACKR1

2.82e-06195906023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

TIE1 TIMP3 CYP4B1 TSPAN7 TEK ACKR1

2.82e-061959066b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A1 TIE1 TIMP3 TSPAN7 TEK ACKR1

2.91e-061969069b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD9 TIE1 SLCO2B1 TSPAN7 MAP3K11 TEK

2.91e-06196906b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ComputationalPorins / transporters.

MST1R TIE1 KCNQ3 S1PR2 GRIK3 ITGA2B TEK

6.43e-05211527MODULE_63
ComputationalMembranal receptors.

MST1R CD9 WNT2 TSPAN7 RRH KCNQ3 ITGA2B TEK ACKR1 SLC4A3

1.55e-045175210MODULE_64
ComputationalGenes in the cancer module 27.

MST1R TIE1 RRH S1PR2 GRIK3 ITGA2B TEK ACKR1

2.76e-04355528MODULE_27
Drugkainite

MAP3K10 MAP3K11 GRIA3 GRIA4 GRIK3 MAP3K13 GRIN2B

6.22e-1135887CID000164810
Drugsodium

IFIH1 SLC7A1 SLC7A4 SLC12A1 SLC12A2 SLC7A13 TIMP3 SLCO2B1 SLC9B2 GRIA3 GRIA4 SLC28A3 GRIK3 SIT1 ATP2B2 SLC4A3 ATP2B4 SLC3A2 SLC4A2

2.70e-099448819CID000000923
Drug6,7-dinitroquinoxaline

MAP3K11 GRIA3 GRIA4 GRIK3 GRIN2B

1.68e-0733885CID002724608
Drugifenprodil

ADRA1A EBPL GRIA3 GRIA4 GRIK3 GRIN2B

3.28e-0771886CID000003689
DrugD-N-Q

MAP3K11 GRIA3 GRIA4 GRIK3 MAP3K13 GRIN2B

8.95e-0784886CID000003140
DrugIDRA 21

GRIA3 GRIA4 GRIK3 GRIN2B

9.63e-0720884CID000003688
Drugxenon

MAP3K9 GRIA3 GRIA4 GRIN2B ATP2B2 ATP2B4

1.18e-0688886CID000023991
DrugNS 102

GRIA3 GRIA4 GRIK3 GRIN2B

1.44e-0622884CID005282252
DrugCX516

GRIA3 GRIA4 GRIK3 GRIN2B

1.44e-0622884CID000148184
DrugAC1L1EKQ

GRIA3 GRIA4 GRIK3 GRIN2B ITGA2B

1.73e-0652885CID000002834
DrugNs102

MAP3K11 GRIA3 GRIA4 GRIK3

2.48e-0625884CID005311098
DrugGYKI 52466

MAP3K11 GRIA3 GRIA4 GRIK3 GRIN2B

3.00e-0658885CID000003538
DrugAC1NUW3V

GRIA3 GRIA4 GRIK3 GRIN2B

4.60e-0629884CID005462126
DrugLy294486

GRIA3 GRIA4 GRIK3

4.61e-069883CID005311255
DrugLY293558

GRIA3 GRIA4 GRIK3 GRIN2B

5.29e-0630884CID000127894
Drug4-methylglutamic acid

GRIA3 GRIA4 GRIK3 GRIN2B

6.05e-0631884CID000005365
Drugsym 2206

GRIA3 GRIA4 GRIK3

9.00e-0611883CID005039877
DrugR,S)-AMPA

GRIA3 GRIA4 GRIK3 GRIN2B

1.12e-0536884CID000001221
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A

SLCO1C1 SLCO2B1 GRIA3 GRIK3 MAP3K13 SIT1 ATP2B2

1.18e-051988874265_UP
DrugAtpa

GRIA3 GRIA4 GRIK3

1.20e-0512883CID000002252
Druggamma-Glu-Gly

GRIA3 GRIA4 GRIK3 GRIN2B

1.25e-0537884CID000100099
DrugCGS 19755

GRIA3 GRIA4 GRIK3 GRIN2B

1.39e-0538884CID000068736
DrugGAMs

GRIA3 GRIA4 GRIK3 GRIN2B

1.39e-0538884CID000002935
DrugL-BMAA

GRIA3 GRIA4 GRIK3 GRIN2B

1.39e-0538884CID000028558
DrugDETC-MeSO

GRIA3 GRIA4 GRIK3 GRIN2B

1.55e-0539884CID003035711
DrugHA-966

GRIA3 GRIA4 GRIK3 GRIN2B

1.55e-0539884CID000001232
DrugNaspm

GRIA3 GRIA4 GRIN2B

1.55e-0513883CID000129695
DrugAC1L1B1W

SLC12A2 GRIA3 GRIA4 GRIK3 GRIN2B

1.87e-0584885CID000001248
DrugAC1NNRU4

SLC12A1 GRIA3 GRIA4 GRIN2B

1.89e-0541884CID005126051
DrugLY341495

GRIA3 GRIA4 GRIK3 GRIN2B

2.29e-0543884CID006324636
DrugJoro spider toxin

GRIA3 GRIA4 GRIK3 GRIN2B

2.29e-0543884CID000119582
DrugLY 300164

KCNQ3 GRIA3 GRIA4 GRIK3

2.29e-0543884CID000126756
Drugthiokynurenic acid

GRIA3 GRIA4 GRIN2B

2.45e-0515883CID003035667
DrugAC1LAD18

MAP3K9 MAP3K10 MAP3K11 MAP3K13

2.51e-0544884CID000466138
Drugphilanthotoxin

GRIA3 GRIA4 GRIK3 GRIN2B

2.75e-0545884CID000115201
Drug7-chlorokynurenic acid

GRIA3 GRIA4 GRIK3 GRIN2B

2.75e-0545884CID000001884
Drugaurintricarboxylic acid

GRIA3 GRIA4 GRIK3 GRIN2B ITGA2B

2.75e-0591885CID000002259
DrugLY233536

GRIA3 GRIA4 GRIN2B

3.01e-0516883CID000126239
Drugdecahydroisoquinoline

GRIA3 GRIA4 GRIK3

3.01e-0516883CID000097812
DrugODAP

GRIA3 GRIA4 GRIK3 SLC3A2

3.56e-0548884CID000002360
Drug7-Cl-Thio-Kyna

GRIA3 GRIA4 GRIN2B

3.65e-0517883CID003035668
Drugmethylenecyclopropylglycine

GRIA3 GRIA4 GRIK3 GRIN2B

3.87e-0549884CID000441452
DrugAC1L1FA8

GRIA3 GRIA4 GRIK3 GRIN2B

4.19e-0550884CID000003150
DrugMNQX

GRIA3 GRIA4 GRIN2B

4.37e-0518883CID000130818
Drugbromide;iodide

SLC12A1 SLC12A2

4.42e-053882CID009907214
Drugmetrenperone

A1BG ADRA1A

4.42e-053882CID000072005
DrugM100907

ADRA1A GRIA3 GRIA4 GRIN2B

4.53e-0551884CID000060858
DrugLY354740

GRIA3 GRIA4 GRIK3 GRIN2B

4.53e-0551884CID000114827
DrugQuinoxaline

GRIA3 GRIA4 GRIK3 GRIN2B

4.90e-0552884CID000007045
DrugLY382884

GRIA3 GRIA4 GRIK3

5.17e-0519883CID000656723
DrugAC1L1B62

GRIA3 GRIA4 GRIK3

7.06e-0521883CID000001299
DrugAnisomycin [22862-76-6]; Down 200; 15uM; HL60; HT_HG-U133A

SLC7A1 MGAT1 CD9 TSPAN14 ATP2B4 SEMA4C

7.80e-051838861304_DN
DrugCEP-1347

MAP3K9 MAP3K10 MAP3K11 MAP3K13

8.06e-0559884CID000133005
Drugoleth-3-phosphate

CD9 TSPAN7 CD81 ATP2B4

8.61e-0560884CID000021452
Drug3-pyridazinol 1-oxide

GRIA3 GRIA4

8.82e-054882CID000574311
DrugErgoloid mesylate

ADRA1A SLCO2B1

8.82e-054882DB01049
Drugsalmeterol xinafoate

A1BG ADRA1A AGTRAP

9.34e-0523883CID000056801
DrugCGP 39653

GRIA3 GRIA4 GRIN2B

1.06e-0424883CID006437837
DrugSkimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ADRA1A TIMP3 TSPAN7 ITGA2B NEB ATP2B2

1.07e-041948866066_UP
Drug5707885; Up 200; 50uM; PC3; HT_HG-U133A

SLC7A1 MAP3K13 NEB SIT1 PIGZ SEMA4C

1.11e-041958866390_UP
DrugPropofol [2078-54-8]; Up 200; 22.4uM; PC3; HT_HG-U133A

TMPRSS6 KCNQ3 OCA2 MAP3K13 ITGA2B NEB

1.20e-041988866707_UP
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A

TIMP3 TMPRSS6 OCA2 ACKR1 SIT1 ATP2B4

1.24e-041998866069_UP
DrugCP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A

ADRA1A AATK TMPRSS6 RRH GRIA4 MAP3K13

1.27e-042008863825_UP
DrugL-Glutamic Acid

GRIA3 GRIA4 GRIK3 GRIN2B

1.40e-0468884DB00142
DrugAC1L1YEG

GRIA3 GRIA4

1.47e-045882CID000063114
DrugChicago acid

GRIA3 GRIA4

1.47e-045882CID000065740
DrugCHEBI:570577

GRIA3 GRIA4

1.47e-045882CID011334126
DrugL-Lysine

SLC7A1 SLC7A4

1.47e-045882DB00123
DrugQuinethazone

SLC12A1 SLC12A2

1.47e-045882DB01325
Drug1-BCP

GRIA3 GRIA4

1.47e-045882CID000001370
Drugirampanel

GRIA3 GRIA4

1.47e-045882CID003038472
Drugbeta-N-oxalylaminoalanine

GRIA3 GRIA4

1.47e-045882CID000107978
DrugBumetanide

SLC12A1 SLC12A2

1.47e-045882DB00887
DrugLY395153

GRIA3 GRIA4

1.47e-045882CID000656707
Drug5-h PCA

GRIA3 GRIA4

1.47e-045882CID000129091
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

SLC12A1 SLC12A2 SLCO2B1 WNT2 SLC4A3 SLC4A2

1.49e-04206886CID000040600
Druganiracetam

GRIA3 GRIA4 GRIK3 OCA2 GRIN2B

1.51e-04130885CID000002196
Drugfelbamate

GRIA3 GRIA4 GRIK3 GRIN2B

1.57e-0470884CID000003331
Drugbenzamil

SLC12A1 SLC12A2 SLC9B2 GRIA4

1.75e-0472884CID000108107
DrugAC1LAIW3

MAP3K9 MAP3K10 MAP3K11 MAP3K13

1.75e-0472884CID000469261
DrugAC1L8WBM

IFIH1 SLC12A1 GRIA3 GRIA4 ACKR1

1.80e-04135885CID000388647
DrugAC1L9FMM

GRIA3 GRIA4 GRIK3 GRIN2B

1.85e-0473884CID000444055
Drugrufinamide

KCNQ3 GRIA3 GRIA4

1.90e-0429883CID000129228
DrugAC1L1E5T

SLC12A2 GRIA3 GRIA4 GRIK3

1.95e-0474884CID000002653
DrugAC1L1DME

GRIA3 GRIA4 GRIK3 GRIN2B

2.05e-0475884CID000002414
Drugcis-2,3-piperidine dicarboxylic acid

GRIA4 GRIK3 GRIN2B

2.10e-0430883CID000001226
DrugAC1L32TU

GRIA3 GRIA4 GRIN2B

2.10e-0430883CID000107831
Drug2-amino-3-phosphonopropionic acid

GRIA3 GRIA4 GRIK3 GRIN2B

2.16e-0476884CID000003857
Drug2cmo

GRIA3 GRIA4

2.19e-046882CID006914597
DrugYM928

GRIA3 GRIA4

2.19e-046882CID006918393
DrugPotassium Chloride

SLC12A1 SLC12A2

2.19e-046882DB00761
DrugLY 171555

ADRA1A RRH GRIA3 GRIA4 GRIN2B

2.27e-04142885CID000001257
Drugwillardine

GRIA3 GRIA4 GRIK3

2.55e-0432883CID000005123
Drugalpha-methyl-4-carboxyphenylglycine

GRIA3 GRIA4 GRIN2B

2.55e-0432883CID000001222
Drug17beta-estradiol glucuronide

SLCO1C1 CD9 SLCO2B1

2.55e-0432883CID000066424
Drug3-iodothyronamine

SLC7A1 SLC9A4 SLC28A3

2.80e-0433883ctd:C487948
DrugQX-314

GRIA3 GRIA4 GRIK3 GRIN2B

2.90e-0482884CID000003925
Drug2-butenedioate

GRIA3 GRIA4 GRIK3 GRIN2B ATP2B2 ATP2B4

2.97e-04234886CID000000723
DrugD-CPPene

GRIA3 GRIA4 GRIN2B

3.06e-0434883CID006435801
Drugthio-ATPA

GRIA3 GRIA4

3.06e-047882CID005289517
Diseasebipolar I disorder

FADS1 GPR35 PCDHA1 TMEM178B ATP2B2 ATP2B4

3.93e-06141876EFO_0009963
Diseasetotal iron binding capacity

FADS1 TMPRSS6 GRIK3 SLC44A4

8.51e-0578874EFO_0006334
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B2 ATP2B4

1.28e-046872DOID:0050429 (implicated_via_orthology)
Diseaseinterleukin 18 receptor accessory protein measurement

SLC9A4 IL18RAP

3.05e-049872EFO_0008179
Diseasecarbohydrate measurement

TEK ATP2B2 ATP2B4

3.43e-0446873EFO_0004998
Diseaseinflammatory bowel disease

IFIH1 SLC9A4 RPS6KA4 GPR35 TSPAN14 IL18RAP NDFIP1

3.70e-04449877EFO_0003767
Diseaseinterleukin 1 receptor-like 1 measurement

SLC9A4 IL18RAP

4.65e-0411872EFO_0008168
Diseaseserum ST2 measurement

SLC9A4 IL18RAP

4.65e-0411872EFO_0005416
Diseaseneutrophil count, basophil count

PCDHA11 S1PR2 PCDHA1 ACKR1 NDFIP1

5.37e-04224875EFO_0004833, EFO_0005090
DiseaseMetastatic melanoma

MAP3K9 MAP3K10 MAP3K13

5.51e-0454873C0278883
Diseaseecosanoids measurement

FADS1 SLCO1C1 CYP4B1

5.81e-0455873EFO_0020044
Diseasetransferrin receptor protein 1 measurement

TMPRSS6 NDFIP1

7.64e-0414872EFO_0802142
Diseaseinterleukin 18 receptor 1 measurement

SLC9A4 IL18RAP

8.80e-0415872EFO_0008178
Diseaseanemia (implicated_via_orthology)

SLC4A3 SLC4A2

8.80e-0415872DOID:2355 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

TSPAN7 GRIA3 GRIA4 GRIK3

9.08e-04145874DOID:1289 (implicated_via_orthology)
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA3 GRIA4

1.00e-0316872DOID:331 (implicated_via_orthology)
Diseaseautoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis

SLC9A4 GPR35 IL18RAP

1.18e-0370873EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
DiseaseST2 protein measurement

SLC9A4 IL18RAP

1.74e-0321872EFO_0010599
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

IFIH1 RPS6KA4 GPR35 TSPAN14 NDFIP1

1.83e-03295875EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
DiseaseEpilepsy, Benign Psychomotor, Childhood

SLC12A2 TEK

2.09e-0323872C0393672
DiseaseEpilepsy, Lateral Temporal

SLC12A2 TEK

2.09e-0323872C0393682
DiseaseUncinate Epilepsy

SLC12A2 TEK

2.09e-0323872C0014558
DiseaseEpilepsy, Temporal Lobe

SLC12A2 TEK

2.09e-0323872C0014556
Diseaseneutrophil count

MST1R IFIH1 FADS1 AATK TIE1 PCDHA11 S1PR2 TSPAN14 PCDHA1 ACKR1 NDFIP1

2.44e-0313828711EFO_0004833
Diseasebreast carcinoma (is_implicated_in)

TIMP3 WNT2

2.47e-0325872DOID:3459 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
VGRVWIGFWLVFLAL

SLC4A2

791

P04920
DLEYLTGRVWVGLWL

SLC4A3

786

P48751
TGRVWVGLWLVVFVL

SLC4A3

791

P48751
LLCEVLLGWLNGFWI

CATSPER4

136

Q7RTX7
WALSLVISIGPLFGW

ADRA1A

151

P35348
IFWWPHGVVLGLDFL

ACKR1

251

Q16570
GELWAFLIGWNVLLE

SLC7A4

111

O43246
FWLAGGVILGVALWL

CD81

21

P60033
WCIFIGLGELVWGQV

ATP2B2

1066

Q01814
LSQWLWCLFIGIGEL

ATP2B4

1026

P23634
WCLFIGIGELLWGQF

ATP2B4

1031

P23634
GLTSGRWFLRQGWLL

ARHGEF39

221

Q8N4T4
IHLDLGWIAILGAIW

OCA2

646

Q04671
GWIAILGAIWLLILA

OCA2

651

Q04671
YIGLILGAWINGLFW

RRH

141

O14718
VFLLLWGVTWGPVTE

A1BG

6

P04217
LWLLLLEFWEVGSGQ

PCDHA11

16

Q9Y5I1
GFWWLIELLVLVGEY

DNAJC14

251

Q6Y2X3
WIFLWLVAGERIKGF

IL18RAP

6

O95256
VWSFGVLLWELLTGE

MAP3K10

286

Q02779
SAGLVLWGAILFVAW

MGAT1

6

P26572
GLGWLLLAELWAELE

MGAT1

266

P26572
WASLGLLLVFLGILW

LEMD2

216

Q8NC56
ALWWGLITLATIGYG

KCNQ3

306

O43525
RIVGGVWWFFTLIII

GRIA3

631

P42263
RIVGGVWWFFTLIII

GRIA4

621

P48058
LWILLGLLLWSDPGT

PGLYRP2

6

Q96PD5
VFSGNELGALLGWWL

PGM2

341

Q96G03
FFNGVWVLIPGLLLW

EBPL

171

Q9BY08
GKAVDWWSLGILLFE

RPS6KA4

216

O75676
WWSLGILLFELLTGA

RPS6KA4

221

O75676
WVLVIGSLVARWLLG

GPR35

141

Q9HC97
LWLLLLAAWEVGSGQ

PCDHA1

16

Q9Y5I3
IWSFGVVLWELLTGE

MAP3K13

336

O43283
WWIFLVLGLLLFFRG

NDFIP2

296

Q9NV92
WWVFLVLGFLLFLRG

NDFIP1

181

Q9BT67
FWLAGIAVLAIGLWL

CD9

21

P21926
WLLAADLLILTWIGG

MT-CYB

326

P00156
WLALLLGALLGTAWA

CNPY2

6

Q9Y2B0
LLLSTLEKGVWHLGW

IFIH1

61

Q9BYX4
TRWALLLLFWLGWLG

SLC3A2

181

P08195
LLDGAAWLTLWVFGT

FADS1

141

O60427
WLLILVLEGLWLGLT

HGSNAT

421

Q68CP4
GVLGLFWTLNWVLAL

SLC44A4

446

Q53GD3
WIGRGLLVLEGPKWL

CYP4B1

121

P13584
WKGGLSWALLLLLLG

CST9L

6

Q9H4G1
RIIGGIWWFFTLIII

GRIK3

636

Q13003
GWRALVDGQALWLLI

FBXO27

56

Q8NI29
WLISLVLGGLPILGW

S1PR2

156

O95136
WSFGVLLWELLTGEV

MAP3K11

306

Q16584
DVWSYGVLLWELLTG

MAP3K9

331

P80192
IILFGWIIGVLGCCW

TMEM178B

181

H3BS89
SLQWLGDWLVLSGGL

SSPOP

281

A2VEC9
WAAAIQGLWALISGL

SLC18B1

406

Q6NT16
WSLGVTIWELFELGT

AATK

321

Q6ZMQ8
DIWSYGVLLWELLTG

MAP3K21

326

Q5TCX8
AAVTWLLGEPVLWLG

RETREG1

66

Q9H6L5
GLVLGLGALGLVWWL

MPIG6B

151

O95866
LLGLPWQWGFILGFV

SLC9B2

226

Q86UD5
GSILWWAVLGALINA

SLC9A4

156

Q6AI14
WLLLWAKLGDWLLGT

SMIM40

56

Q5STR5
IDVWWLFDDGGLTLL

SLC12A1

911

Q13621
WRPVLWGIGLQFLLG

SLC28A3

226

Q9HAS3
PIWWVLVGVLGGLLL

ITGA2B

996

P08514
AVWLLAARLWGLGIG

SEMA4C

6

Q9C0C4
WGSWGLGFLDALINV

OR8S1

146

Q8NH09
ILLGHWLLTTWGCIV

AGTRAP

11

Q6RW13
GGIWLWLPLLLTWLT

WNT2

6

P09544
AVGKLLTLGGLGIWW

TM2D2

176

Q9BX73
LTLGGLGIWWFVDLI

TM2D2

181

Q9BX73
LGIWWFVDLILLITG

TM2D2

186

Q9BX73
LGALFLAIGLWAWGE

TSPAN17

31

Q96FV3
LAIGLWAWGEKGVLS

TSPAN17

36

Q96FV3
LFLSLRLWAWRGGGE

TVP23C

241

Q96ET8
LWLLSWLLALAGGVI

ROM1

21

Q03395
WWLGFLIAAGAVALA

SLCO2B1

276

O94956
VGLLWLASVTLGIWQ

TMEM181

421

Q9P2C4
GELWAFITGWNLILS

SLC7A1

106

P30825
VWSFGVLLWEIVSLG

TIE1

1036

P35590
LWLIFFTPGWTLIDG

PRSS35

6

Q8N3Z0
VWWLFDDGGLTLLIP

SLC12A2

1026

P55011
VGAWWLGYLIAGIIS

SLCO1C1

271

Q9NYB5
GWSLALGWISFIAEL

TMEM114

186

B3SHH9
WWGTSFLLINIIGAG

SLC7A13

16

Q8TCU3
VWSYGVLLWEIVSLG

TEK

1021

Q02763
VLWGGLSLLRVLWCL

PIGZ

36

Q86VD9
GLWPALLGIVLAAWL

UNC5A

6

Q6ZN44
LLWGYLLELWTGGHT

SEMA3E

11

O15041
FWLAGVVFLGVGLWA

TSPAN14

26

Q8NG11
EVLWWGGVFLILCGL

TMEM42

126

Q69YG0
LSLLGWILWYTGNIE

TMEM238

81

C9JI98
FWITGVILLAVGVWG

TSPAN7

26

P41732
WSFGVLLWELLTRGA

MST1R

1271

Q04912
AWGLWVLLGAVTLLF

SIT1

41

Q9Y3P8
TLGAVWLGLLLNSLW

TRAV2

6

A0A0B4J234
GLIVLLGSWSLGDWG

TIMP3

6

P35625
LSGRWFLAGLVSWGL

TMPRSS6

771

Q8IU80
TIGKAIWLLWGLVFN

GRIN2B

601

Q13224
LEWLRGIGWSPLGSL

NEB

2416

P20929