Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Sec7	ARFGEF2 FBXO8	3.73e-04	15	36	2	PF01369
Domain	Sec7_alpha_orthog	ARFGEF2 FBXO8	3.73e-04	15	36	2	IPR023394
Domain	-	ARFGEF2 FBXO8	3.73e-04	15	36	2	1.10.1000.11
Domain	Sec7	ARFGEF2 FBXO8	4.26e-04	16	36	2	SM00222
Domain	Sec7_dom	ARFGEF2 FBXO8	4.26e-04	16	36	2	IPR000904
Domain	SEC7	ARFGEF2 FBXO8	4.26e-04	16	36	2	PS50190
Domain	P-loop_NTPase	MYO15B NLRP7 GAL3ST1 SUPV3L1 SPEF2 MX1	5.22e-03	848	36	6	IPR027417
Domain	F-box	FBXO40 FBXO8	7.38e-03	67	36	2	PF00646
Domain	FBOX	FBXO40 FBXO8	8.48e-03	72	36	2	PS50181
Domain	F-box_dom	FBXO40 FBXO8	9.18e-03	75	36	2	IPR001810
Domain	IQ_motif_EF-hand-BS	LRRIQ3 MYO15B	1.30e-02	90	36	2	IPR000048
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	FAF2 ACACA SERPINB12 HSPH1	8.39e-05	224	36	4	32941674
Pubmed	Characterization of human colon cancer antigens recognized by autologous antibodies.	CWC27 HSPH1	1.24e-04	16	36	2	9610721
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FBXO40 INTU PRDM10	1.68e-04	103	36	3	10574462
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ARFGEF2 CCN1 ABHD12 FAM8A1 FRMD5 HSPH1 SCAPER	2.00e-04	1201	36	7	35696571
Pubmed	Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.	ARHGEF12 SCAPER	2.16e-04	21	36	2	16618939
Pubmed	A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.	KDM3A ACACA	2.60e-04	23	36	2	28162974
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	RIC8A FAF2 CCN1 ABHD12 FAM8A1 HSPH1	3.78e-04	942	36	6	31073040
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RIC8A FAF2 ACACA SRSF9 SERPINB12 SUPV3L1 HSPH1	4.12e-04	1353	36	7	29467282
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RIC8A FAF2 ACACA SRSF9 HSPH1	4.82e-04	638	36	5	33239621
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	FAF2 SRSF9 SERPINB12 MX1 HSPH1	5.13e-04	647	36	5	26618866
Pubmed	TRIB3 promotes pulmonary fibrosis through inhibiting SLUG degradation by physically interacting with MDM2.	ASCC1 CWC27	5.72e-04	34	36	2	37139431
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGEF12 TRIL INTU FAF2	8.10e-04	407	36	4	12693553
Pubmed	Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.	FAF2 FAM8A1	8.74e-04	42	36	2	32738194
Cytoband	6p21.31	PXT1 BNIP5	4.81e-04	41	36	2	6p21.31
GeneFamily	Cyclins\|F-boxes other	FBXO40 FBXO8	1.21e-03	39	24	2	560
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO15B FRMD5	1.99e-03	50	24	2	1293
GeneFamily	PDZ domain containing	ARHGEF12 INTU	1.72e-02	152	24	2	1220
Disease	glycerophospholipid measurement	ABHD12 GAL3ST1	1.55e-03	49	35	2	EFO_0007630
Disease	age at menopause	FAF2 ACACA ABHD12	5.45e-03	302	35	3	EFO_0004704

Protein segments in the cluster

Peptide	Gene	Start	Entry
APFKDEFHSRLRFNR	CWC27	81	Q6UX04
AFPFYRLFNDIHKFR	CCN1	366	O00622
NFRFQKDFLRPFEHI	ARFGEF2	1176	Q9Y6D5
NYEVDRRFHREFPKF	ACACA	1341	Q13085
RRKQPFTHFLAFFLN	ASCC1	156	Q8N9N2
KETRRIFLEFHQFFL	ARHGEF12	416	Q9NZN5
ARSFRDFKVQFVPFH	ABHD12	351	Q8N2K0
NFKRFHGRAFNDPFI	HSPH1	66	Q92598
RNQFLPNALREFFRH	FBXO8	206	Q9NRD0
AALQHLFIRKSFRPF	PRDM10	516	Q9NQV6
LDHFFNLFFQRALQP	INTU	431	Q9ULD6
FLRKEVFYPRENFSH	MYO15B	1246	Q96JP2
FRFGQKHRLKFAFPN	GAL3ST1	96	Q99999
FFRDIRQTPEFEQFH	FRMD5	531	Q7Z6J6
VFCRFFHFRRLQFNK	KDM3A	566	Q9Y4C1
QIRRHPSFKRFFYEF	BNIP5	556	P0C671
KFFRRDEFPLHFKNV	FBXO40	481	Q9UH90
RFFNSFAALHLPAFQ	SCAPER	1221	Q9BY12
FFPAFITLLFFQHNR	FAM8A1	381	Q9UBU6
PFNRQEHLIEFFFRL	SPEF2	1601	Q9C093
KNRHGLVPFAFVRFE	SRSF9	46	Q13242
FRLRPVFNASVQFLH	TGFBR3L	156	H3BV60
EIFFQNFHEVPAKFF	FER1L5	211	A0AVI2
FKLPNDSRVERRFHF	FAF2	366	Q96CS3
FHDDVTLRNQRFIPF	NLRP7	146	Q8WX94
DDLFPFFLRHAKQIF	SUPV3L1	156	Q8IYB8
FPHDVQFFDLRLLFL	RIC8A	156	Q9NPQ8
VEFNANHPFLFFIRH	SERPINB12	376	Q96P63
FKTRFRLDFPFDLQE	CLCN2	306	P51788
FRKIYQFLFPFHEDN	CLUL1	146	Q15846
FDFLEFLNHQRFEPM	ZNF865	31	P0CJ78
RAHSEQFNAFFRLPK	TBC1D8B	281	Q0IIM8
RLLFDRFGQQPKFHR	TRIL	621	Q7L0X0
DHFVFFFFRRVQVLL	PXT1	111	Q8NFP0
PERFKACNHRLFFNF	LRRIQ3	171	A6PVS8
LQREKIFFENHPYFR	MX1	296	P20591