Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF658B ZNF454 ZBTB1 CREBBP UTY EP300 CASZ1 MEIS1 ZNF585B	1.72e-10	1459	62	22	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF615 ZSCAN25 ZNF658B ZNF454 ZBTB1 UTY EP300 MEIS1 ZNF585B	3.56e-09	1244	62	19	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF615 ZSCAN25 ZNF658B ZNF454 ZBTB1 UTY EP300 MEIS1 ZNF585B	5.06e-09	1271	62	19	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF658B ZNF454 ZBTB1 CASZ1 MEIS1 ZNF585B	2.79e-08	1412	62	19	GO:0000981
GeneOntologyMolecularFunction	SMAD binding	HIPK2 ZMIZ1 CREBBP EP300 PPM1A	7.03e-06	86	62	5	GO:0046332
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF131 CTCFL ZNF585A ZNF484 ZNF658 ZNF615 ZNF658B CASZ1 MEIS1 ZNF585B	8.05e-06	560	62	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF131 CTCFL ZNF585A ZNF484 ZNF658 ZNF615 ZNF658B CASZ1 MEIS1 ZNF585B	8.83e-06	566	62	10	GO:0001216
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	9.49e-06	2	62	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	9.49e-06	2	62	2	GO:0044017
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	BRPF3 CREBBP EP300	1.26e-05	15	62	3	GO:0010484
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	2.84e-05	3	62	2	GO:0043993
GeneOntologyMolecularFunction	histone acetyltransferase activity	BRPF3 CREBBP EP300	5.34e-04	51	62	3	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	BRPF3 CREBBP EP300	6.67e-04	55	62	3	GO:0061733
GeneOntologyMolecularFunction	histone modifying activity	BRPF3 CREBBP UTY PCGF5 EP300	7.22e-04	229	62	5	GO:0140993
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	BRPF3 CREBBP EP300	8.60e-04	60	62	3	GO:0034212
GeneOntologyMolecularFunction	protein antigen binding	LPA EP300	1.11e-03	16	62	2	GO:1990405
GeneOntologyMolecularFunction	p53 binding	ZNF385B CREBBP EP300	1.77e-03	77	62	3	GO:0002039
GeneOntologyMolecularFunction	chromatin DNA binding	CTCFL CREBBP UTY EP300	1.81e-03	167	62	4	GO:0031490
GeneOntologyMolecularFunction	N-acetyltransferase activity	BRPF3 CREBBP EP300	1.84e-03	78	62	3	GO:0008080
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP EP300	1.92e-03	21	62	2	GO:0042975
GeneOntologyMolecularFunction	histone H4 acetyltransferase activity	BRPF3 EP300	2.30e-03	23	62	2	GO:0010485
GeneOntologyMolecularFunction	transcription coactivator activity	HIPK2 ZMIZ1 TRRAP CREBBP EP300	2.49e-03	303	62	5	GO:0003713
GeneOntologyMolecularFunction	N-acyltransferase activity	BRPF3 CREBBP EP300	3.93e-03	102	62	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	BRPF3 CREBBP EP300	4.15e-03	104	62	3	GO:0016407
GeneOntologyMolecularFunction	bHLH transcription factor binding	CREBBP EP300	5.89e-03	37	62	2	GO:0043425
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF131 CTCFL ERCC6 ZNF585A ZNF484 ZNF658 HIPK2 IKZF1 ZNF615 ZMIZ1 CHURC1 ZNF658B CREBBP PCGF5 EP300 CASZ1 MEIS1 ZNF585B	5.96e-08	1390	61	18	GO:0045944
GeneOntologyBiologicalProcess	retina morphogenesis in camera-type eye	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1	6.94e-06	90	61	5	GO:0060042
GeneOntologyBiologicalProcess	chromatin organization	CTCFL BRPF3 ERCC6 HIPK2 IKZF1 ZNF518B TRRAP ZBTB1 CREBBP UTY PCGF5 EP300	1.02e-05	896	61	12	GO:0006325
GeneOntologyBiologicalProcess	camera-type eye morphogenesis	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1 MEIS1	1.13e-05	171	61	6	GO:0048593
GeneOntologyBiologicalProcess	neural retina development	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1	1.28e-05	102	61	5	GO:0003407
GeneOntologyBiologicalProcess	protein-DNA complex organization	CTCFL BRPF3 ERCC6 HIPK2 IKZF1 ZNF518B TRRAP ZBTB1 CREBBP UTY PCGF5 EP300	3.02e-05	999	61	12	GO:0071824
GeneOntologyBiologicalProcess	eye morphogenesis	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1 MEIS1	3.07e-05	204	61	6	GO:0048592
GeneOntologyBiologicalProcess	N-terminal peptidyl-lysine acetylation	CREBBP EP300	5.14e-05	4	61	2	GO:0018076
GeneOntologyBiologicalProcess	lens morphogenesis in camera-type eye	HIPK1 HIPK2 MEIS1	7.65e-05	28	61	3	GO:0002089
GeneOntologyBiologicalProcess	N-terminal protein amino acid modification	CREBBP EP300 PPM1A	8.51e-05	29	61	3	GO:0031365
GeneOntologyBiologicalProcess	embryonic retina morphogenesis in camera-type eye	HIPK1 HIPK2	1.28e-04	6	61	2	GO:0060059
GeneOntologyBiologicalProcess	response to UV	ERCC6 PTPRK ZBTB1 CREBBP EP300	1.35e-04	167	61	5	GO:0009411
GeneOntologyBiologicalProcess	positive regulation of cellular response to transforming growth factor beta stimulus	HIPK2 CREBBP EP300	1.51e-04	35	61	3	GO:1903846
GeneOntologyBiologicalProcess	positive regulation of transforming growth factor beta receptor signaling pathway	HIPK2 CREBBP EP300	1.51e-04	35	61	3	GO:0030511
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	PTPRK HIPK2 ZMIZ1 CREBBP EP300 PPM1A	1.63e-04	276	61	6	GO:0007179
GeneOntologyBiologicalProcess	intrinsic apoptotic signaling pathway by p53 class mediator	HIPK1 HIPK2 ZNF385B EP300	1.66e-04	93	61	4	GO:0072332
GeneOntologyBiologicalProcess	trans-synaptic signaling by BDNF, modulating synaptic transmission	LPA NTRK2	1.79e-04	7	61	2	GO:0099183
GeneOntologyBiologicalProcess	lens induction in camera-type eye	HIPK1 HIPK2	1.79e-04	7	61	2	GO:0060235
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZNF131 SLFN12L PTPRK ZNF658 ZBTB25 HIPK1 HIPK2 PHF6 IKZF1 ZBTB1 CREBBP EP300 PPM1A	1.86e-04	1399	61	13	GO:0045892
GeneOntologyBiologicalProcess	cellular response to UV	PTPRK ZBTB1 CREBBP EP300	1.95e-04	97	61	4	GO:0034644
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZNF131 SLFN12L PTPRK ZNF658 ZBTB25 HIPK1 HIPK2 PHF6 IKZF1 ZBTB1 CREBBP EP300 PPM1A	2.06e-04	1413	61	13	GO:1902679
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	ZNF131 SLFN12L ZBTB25 HIPK1 HIPK2 PHF6 IKZF1 ZBTB1 CREBBP EP300 PPM1A	2.32e-04	1053	61	11	GO:0000122
GeneOntologyBiologicalProcess	trans-synaptic signaling by BDNF	LPA NTRK2	2.38e-04	8	61	2	GO:0099191
GeneOntologyBiologicalProcess	animal organ morphogenesis	SULF2 HIPK1 NTRK2 HIPK2 IKZF1 ZMIZ1 UTY EP300 PLXNA1 CASZ1 MEIS1 ALPK2	2.93e-04	1269	61	12	GO:0009887
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair via homologous recombination	ERCC6 TRRAP CREBBP	2.99e-04	44	61	3	GO:1905168
GeneOntologyBiologicalProcess	chromatin remodeling	CTCFL BRPF3 ERCC6 HIPK2 ZBTB1 CREBBP UTY PCGF5 EP300	3.09e-04	741	61	9	GO:0006338
GeneOntologyBiologicalProcess	retina development in camera-type eye	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1	3.99e-04	211	61	5	GO:0060041
GeneOntologyBiologicalProcess	intrinsic apoptotic signaling pathway in response to DNA damage	ERCC6 HIPK1 HIPK2 EP300	4.00e-04	117	61	4	GO:0008630
GeneOntologyBiologicalProcess	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	HIPK1 HIPK2 EP300	4.12e-04	49	61	3	GO:0042771
GeneOntologyBiologicalProcess	iris morphogenesis	HIPK1 HIPK2	4.65e-04	11	61	2	GO:0061072
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	PTPRK HIPK2 ZMIZ1 CREBBP EP300 PPM1A	4.67e-04	336	61	6	GO:0071560
GeneOntologyBiologicalProcess	sensory organ morphogenesis	HIPK1 NTRK2 HIPK2 IKZF1 CASZ1 MEIS1	5.21e-04	343	61	6	GO:0090596
GeneOntologyBiologicalProcess	response to transforming growth factor beta	PTPRK HIPK2 ZMIZ1 CREBBP EP300 PPM1A	5.21e-04	343	61	6	GO:0071559
GeneOntologyBiologicalProcess	cellular response to light stimulus	PTPRK ZBTB1 CREBBP EP300	5.95e-04	130	61	4	GO:0071482
GeneOntologyBiologicalProcess	positive regulation of leukocyte differentiation	PLA2G3 IKZF1 ZMIZ1 ZBTB1 EP300	7.43e-04	242	61	5	GO:1902107
GeneOntologyBiologicalProcess	positive regulation of hemopoiesis	PLA2G3 IKZF1 ZMIZ1 ZBTB1 EP300	7.43e-04	242	61	5	GO:1903708
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	SULF2 PTPRK NTRK2 HIPK2 ZMIZ1 CHURC1 CREBBP EP300 PPM1A	8.32e-04	850	61	9	GO:0071363
GeneOntologyBiologicalProcess	retinal bipolar neuron differentiation	IKZF1 CASZ1	8.81e-04	15	61	2	GO:0060040
GeneOntologyBiologicalProcess	N-terminal protein amino acid acetylation	CREBBP EP300	1.01e-03	16	61	2	GO:0006474
GeneOntologyBiologicalProcess	regulation of cellular response to heat	CREBBP EP300	1.01e-03	16	61	2	GO:1900034
GeneOntologyBiologicalProcess	regulation of hemopoiesis	BRPF3 PLA2G3 IKZF1 ZMIZ1 ZBTB1 EP300 MEIS1	1.04e-03	540	61	7	GO:1903706
GeneOntologyBiologicalProcess	response to growth factor	SULF2 PTPRK NTRK2 HIPK2 ZMIZ1 CHURC1 CREBBP EP300 PPM1A	1.09e-03	883	61	9	GO:0070848
GeneOntologyBiologicalProcess	amacrine cell differentiation	IKZF1 CASZ1	1.28e-03	18	61	2	GO:0035881
GeneOntologyBiologicalProcess	regulation of cell development	BRPF3 NTRK2 PLA2G3 IKZF1 ZMIZ1 ZBTB1 EP300 PLXNA1 CASZ1 MEIS1	1.30e-03	1095	61	10	GO:0060284
GeneOntologyCellularComponent	histone acetyltransferase complex	BRPF3 TRRAP CREBBP EP300	1.75e-04	94	62	4	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	BRPF3 TRRAP CREBBP EP300	2.58e-04	104	62	4	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	BRPF3 TRRAP CREBBP EP300	3.09e-04	109	62	4	GO:1902493
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	9.25e-06	2	16	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	9.25e-06	2	16	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	9.25e-06	2	16	2	HP:0001042
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	2.77e-05	3	16	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	2.77e-05	3	16	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	2.77e-05	3	16	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	2.77e-05	3	16	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	2.77e-05	3	16	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	2.77e-05	3	16	2	HP:0005895
HumanPheno	Deep plantar creases	ERCC6 CREBBP EP300	3.27e-05	21	16	3	HP:0001869
HumanPheno	Abnormal iliac wing morphology	ERCC6 CREBBP EP300 PLEKHM1	4.69e-05	68	16	4	HP:0011867
HumanPheno	Trichiasis	CREBBP EP300	5.53e-05	4	16	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	5.53e-05	4	16	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	5.53e-05	4	16	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	5.53e-05	4	16	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	5.53e-05	4	16	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	5.53e-05	4	16	2	HP:0031207
HumanPheno	Wide nasal bridge	ERCC6 GNE RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	5.78e-05	508	16	8	HP:0000431
HumanPheno	Minor feet anomalies	ERCC6 CREBBP EP300	6.33e-05	26	16	3	HP:0010613
HumanPheno	Abnormal feet morphology	ERCC6 CREBBP EP300	6.33e-05	26	16	3	HP:0010611
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	9.20e-05	5	16	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	9.20e-05	5	16	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	9.20e-05	5	16	2	HP:0030421
HumanPheno	Deeply set eye	ERCC6 PHF6 TRRAP CREBBP EP300 CASZ1	9.85e-05	266	16	6	HP:0000490
HumanPheno	Hypoplastic iliac wing	ERCC6 CREBBP EP300	1.08e-04	31	16	3	HP:0002866
HumanPheno	Visual impairment	ERCC6 NTRK2 ADAMTS17 PHF6 IKZF1 ZMIZ1 TRRAP CREBBP CASZ1 PLEKHM1 TAT	1.27e-04	1174	16	11	HP:0000505
HumanPheno	Delayed myelination	ERCC6 NTRK2 ZMIZ1 TRRAP CREBBP EP300	1.31e-04	280	16	6	HP:0012448
HumanPheno	Large foramen magnum	CREBBP EP300	1.38e-04	6	16	2	HP:0002700
HumanPheno	Aplasia involving bones of the extremities	GNE ADAMTS17 PHF6 RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	1.47e-04	759	16	9	HP:0009825
HumanPheno	Aplasia/hypoplasia involving bones of the extremities	GNE ADAMTS17 PHF6 RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	1.51e-04	761	16	9	HP:0045060
HumanPheno	Smooth philtrum	GNE ZMIZ1 TRRAP CREBBP EP300	1.89e-04	185	16	5	HP:0000319
HumanPheno	Deviated nasal septum	CREBBP EP300	1.92e-04	7	16	2	HP:0004411
HumanPheno	Thickened calvaria	ERCC6 PHF6 PLEKHM1	2.34e-04	40	16	3	HP:0002684
HumanPheno	Abnormal ilium morphology	ERCC6 CREBBP EP300 PLEKHM1	2.47e-04	104	16	4	HP:0002867
HumanPheno	Aplasia/hypoplasia of the extremities	GNE ADAMTS17 PHF6 RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	2.54e-04	813	16	9	HP:0009815
HumanPheno	Juvenile aseptic necrosis	PHF6 CREBBP EP300	2.91e-04	43	16	3	HP:0100323
HumanPheno	Short finger	ADAMTS17 PHF6 RPS26 ZMIZ1 CREBBP EP300	2.98e-04	325	16	6	HP:0009381
HumanPheno	Pilomatrixoma	CREBBP EP300	3.29e-04	9	16	2	HP:0030434
HumanPheno	Cervical cord compression	CREBBP EP300	3.29e-04	9	16	2	HP:0002341
HumanPheno	Hirsutism	ERCC6 GNE CREBBP EP300 CASZ1	3.90e-04	216	16	5	HP:0001007
HumanPheno	Frontal hirsutism	CREBBP EP300	4.10e-04	10	16	2	HP:0011335
HumanPheno	Abnormal lower limb bone morphology	ERCC6 GNE PHF6 ZMIZ1 TRRAP CREBBP EP300 CASZ1 PLEKHM1	4.17e-04	866	16	9	HP:0040069
HumanPheno	Vesicoureteral reflux	ZMIZ1 TRRAP CREBBP EP300 PLXNA1	4.33e-04	221	16	5	HP:0000076
HumanPheno	Abnormal lacrimal duct morphology	TRRAP CREBBP EP300	4.56e-04	50	16	3	HP:0011481
HumanPheno	Cutaneous syndactyly of toes	TRRAP CREBBP EP300	4.56e-04	50	16	3	HP:0010621
HumanPheno	Abnormal subclavian artery morphology	CREBBP EP300	5.00e-04	11	16	2	HP:0031251
HumanPheno	Short thumb	ADAMTS17 RPS26 CREBBP EP300	5.31e-04	127	16	4	HP:0009778
HumanPheno	Abnormal aortic morphology	ERCC6 RPS26 TRRAP CREBBP EP300 CASZ1	5.44e-04	363	16	6	HP:0030963
HumanPheno	Blepharophimosis	ERCC6 PHF6 CREBBP EP300	5.64e-04	129	16	4	HP:0000581
HumanPheno	Macule	ERCC6 IKZF1 CREBBP EP300 CASZ1	5.64e-04	234	16	5	HP:0012733
HumanPheno	Aplasia/Hypoplasia of fingers	ADAMTS17 PHF6 RPS26 ZMIZ1 CREBBP EP300	5.69e-04	366	16	6	HP:0006265
HumanPheno	Abnormality of vision	ERCC6 NTRK2 ADAMTS17 PHF6 IKZF1 ZMIZ1 TRRAP CREBBP CASZ1 PLEKHM1 TAT	5.69e-04	1373	16	11	HP:0000504
HumanPheno	Bilateral cryptorchidism	ERCC6 CREBBP EP300	5.72e-04	54	16	3	HP:0008689
HumanPheno	Low hanging columella	ZMIZ1 CREBBP EP300	6.37e-04	56	16	3	HP:0009765
HumanPheno	Abnormal penis morphology	ERCC6 PHF6 RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	6.38e-04	712	16	8	HP:0000036
HumanPheno	Toe syndactyly	GNE ZMIZ1 TRRAP CREBBP EP300	6.84e-04	244	16	5	HP:0001770
HumanPheno	Abnormal ureter physiology	ZMIZ1 TRRAP CREBBP EP300 PLXNA1	6.97e-04	245	16	5	HP:0025634
HumanPheno	Facial grimacing	CREBBP EP300	7.07e-04	13	16	2	HP:0000273
HumanPheno	Keloids	CREBBP EP300	7.07e-04	13	16	2	HP:0010562
HumanPheno	Abnormal earlobe morphology	PHF6 CREBBP EP300 PLXNA1	7.09e-04	137	16	4	HP:0000363
HumanPheno	Patent ductus arteriosus	RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	7.16e-04	382	16	6	HP:0001643
HumanPheno	Abnormal eyelid morphology	ERCC6 GNE NTRK2 PHF6 IKZF1 RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	7.21e-04	1408	16	11	HP:0000492
HumanPheno	Abnormality of the ureter	ERCC6 ZMIZ1 TRRAP CREBBP EP300 PLXNA1	7.27e-04	383	16	6	HP:0000069
HumanPheno	Abnormality of the lower urinary tract	ERCC6 IKZF1 RPS26 ZMIZ1 TRRAP CREBBP EP300 PLXNA1 CASZ1	7.67e-04	937	16	9	HP:0010936
HumanPheno	Duplication of phalanx of hallux	CREBBP EP300	8.23e-04	14	16	2	HP:0010066
HumanPheno	Hypoplastic aortic arch	CREBBP EP300	8.23e-04	14	16	2	HP:0012304
HumanPheno	Parietal foramina	CREBBP EP300	8.23e-04	14	16	2	HP:0002697
HumanPheno	Abnormal scrotum morphology	PHF6 TRRAP CREBBP EP300	8.33e-04	143	16	4	HP:0000045
HumanPheno	Hypoplastic ilia	ERCC6 CREBBP EP300	9.00e-04	63	16	3	HP:0000946
HumanPheno	Abnormal aortic morphology	ERCC6 RPS26 TRRAP CREBBP EP300 CASZ1	9.29e-04	401	16	6	HP:0001679
HumanPheno	Duplication of phalanx of toe	CREBBP EP300	9.48e-04	15	16	2	HP:0010181
HumanPheno	Social and occupational deterioration	CREBBP EP300	9.48e-04	15	16	2	HP:0007086
HumanPheno	Hydronephrosis	ERCC6 TRRAP CREBBP EP300 CASZ1	9.81e-04	264	16	5	HP:0000126
HumanPheno	Aplasia/Hypoplasia of the thumb	ADAMTS17 RPS26 CREBBP EP300	9.97e-04	150	16	4	HP:0009601
HumanPheno	Coarctation of aorta	RPS26 TRRAP CREBBP EP300	9.97e-04	150	16	4	HP:0001680
HumanPheno	Square face	CREBBP EP300	1.08e-03	16	16	2	HP:0000321
HumanPheno	Dental malocclusion	ERCC6 CREBBP EP300 PLEKHM1	1.16e-03	156	16	4	HP:0000689
HumanPheno	Abnormality of tear glands or tear production	ERCC6 TRRAP CREBBP EP300	1.16e-03	156	16	4	HP:0000521
HumanPheno	Functional abnormality of the bladder	ERCC6 IKZF1 ZMIZ1 TRRAP CREBBP EP300 PLXNA1	1.21e-03	590	16	7	HP:0000009
HumanPheno	Premature thelarche	CREBBP EP300	1.22e-03	17	16	2	HP:0010314
HumanPheno	Brachydactyly (hand)	ADAMTS17 PHF6 RPS26 ZMIZ1 CREBBP EP300	1.34e-03	430	16	6	HP:0100667
HumanPheno	Facial hirsutism	CREBBP EP300	1.37e-03	18	16	2	HP:0009937
HumanPheno	Skin appendage neoplasm	CREBBP EP300	1.37e-03	18	16	2	HP:0012842
HumanPheno	Atypical scarring of skin	ERCC6 CREBBP EP300	1.44e-03	74	16	3	HP:0000987
HumanPheno	Dilatation of the renal pelvis	ERCC6 TRRAP CREBBP EP300 CASZ1	1.50e-03	290	16	5	HP:0010946
HumanPheno	Epicanthus	GNE RPS26 ZMIZ1 TRRAP CREBBP EP300 CASZ1	1.53e-03	614	16	7	HP:0000286
HumanPheno	Broad hallux	ZMIZ1 CREBBP EP300	1.55e-03	76	16	3	HP:0010055
HumanPheno	Abnormal nasal bridge morphology	ERCC6 GNE RPS26 ZMIZ1 TRRAP CREBBP EP300 PLXNA1 CASZ1	1.56e-03	1029	16	9	HP:0000422
HumanPheno	Abnormality of the plantar skin of foot	ERCC6 CREBBP EP300 TAT	1.63e-03	171	16	4	HP:0100872
HumanPheno	Abnormality of the bladder	ERCC6 IKZF1 ZMIZ1 TRRAP CREBBP EP300 PLXNA1	1.64e-03	621	16	7	HP:0000014
HumanPheno	Aplasia/Hypoplasia involving bones of the feet	PHF6 ZMIZ1 TRRAP EP300 CASZ1	1.69e-03	298	16	5	HP:0006494
HumanPheno	Entropion	ERCC6 IKZF1	1.70e-03	20	16	2	HP:0000621
HumanPheno	Absent earlobe	CREBBP EP300	1.70e-03	20	16	2	HP:0000387
HumanPheno	Abnormal renal pelvis morphology	ERCC6 TRRAP CREBBP EP300 CASZ1	1.75e-03	300	16	5	HP:0010944
HumanPheno	Localized hirsutism	CREBBP EP300	1.88e-03	21	16	2	HP:0009889
HumanPheno	Corneal scarring	CREBBP EP300	1.88e-03	21	16	2	HP:0000559
HumanPheno	Abnormal pinna morphology	ERCC6 GNE PHF6 RPS26 ZMIZ1 TRRAP CREBBP EP300 PLXNA1 CASZ1	1.90e-03	1299	16	10	HP:0000377
HumanPheno	Truncal obesity	PHF6 CREBBP EP300	1.94e-03	82	16	3	HP:0001956
HumanPheno	Abnormality of the urethra	IKZF1 RPS26 ZMIZ1 CREBBP EP300 CASZ1	2.02e-03	465	16	6	HP:0000795
HumanPheno	Corneal ulceration	ERCC6 TAT	2.06e-03	22	16	2	HP:0012804
Domain	Znf_C2H2	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ADAMTS17 ZFP28 IKZF1 ZNF385B ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	6.86e-12	805	62	19	IPR007087
Domain	Znf_C2H2-like	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF385B ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	5.63e-11	796	62	18	IPR015880
Domain	ZnF_C2H2	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF385B ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	7.19e-11	808	62	18	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	3.45e-10	775	62	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	3.59e-10	777	62	17	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 ZNF585B	6.18e-10	694	62	16	IPR013087
Domain	-	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF615 ZSCAN25 ZNF454 ZBTB1 ZNF585B	4.18e-09	679	62	15	3.30.160.60
Domain	zf-C2H2	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZNF611 ZFP28 IKZF1 ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	5.50e-09	693	62	15	PF00096
Domain	KRAB	ZNF573 ZNF585A ZNF484 ZNF658 ZNF611 ZFP28 ZNF615 ZSCAN25 ZNF454 ZNF585B	3.46e-07	369	62	10	SM00349
Domain	KRAB	ZNF573 ZNF585A ZNF484 ZNF658 ZNF611 ZFP28 ZNF615 ZSCAN25 ZNF454 ZNF585B	3.55e-07	370	62	10	IPR001909
Domain	KRAB	ZNF573 ZNF585A ZNF484 ZNF658 ZNF611 ZFP28 ZNF615 ZNF454 ZNF585B	2.62e-06	358	62	9	PS50805
Domain	KRAB	ZNF573 ZNF585A ZNF484 ZNF658 ZNF611 ZFP28 ZNF615 ZNF454 ZNF585B	2.62e-06	358	62	9	PF01352
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	1.08e-05	2	62	2	IPR014744
Domain	HAT_KAT11	CREBBP EP300	1.08e-05	2	62	2	PF08214
Domain	KIX	CREBBP EP300	1.08e-05	2	62	2	PS50952
Domain	ZnF_TAZ	CREBBP EP300	1.08e-05	2	62	2	SM00551
Domain	CBP_P300_HAT	CREBBP EP300	1.08e-05	2	62	2	IPR031162
Domain	DUF902	CREBBP EP300	1.08e-05	2	62	2	PF06001
Domain	Ribosomal_S26e	RPS26P11 RPS26	1.08e-05	2	62	2	IPR000892
Domain	-	CREBBP EP300	1.08e-05	2	62	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	1.08e-05	2	62	2	IPR010303
Domain	-	CREBBP EP300	1.08e-05	2	62	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	1.08e-05	2	62	2	PF09030
Domain	RIBOSOMAL_S26E	RPS26P11 RPS26	1.08e-05	2	62	2	PS00733
Domain	Ribosomal_S26e	RPS26P11 RPS26	1.08e-05	2	62	2	PF01283
Domain	-	CREBBP EP300	1.08e-05	2	62	2	1.10.246.20
Domain	zf-TAZ	CREBBP EP300	1.08e-05	2	62	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	1.08e-05	2	62	2	PS50134
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	1.08e-05	2	62	2	IPR013178
Domain	KAT11	CREBBP EP300	1.08e-05	2	62	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	1.08e-05	2	62	2	IPR000197
Domain	KIX_dom	CREBBP EP300	1.08e-05	2	62	2	IPR003101
Domain	KIX	CREBBP EP300	1.08e-05	2	62	2	PF02172
Domain	CBP_P300_HAT	CREBBP EP300	1.08e-05	2	62	2	PS51727
Domain	Bromodomain_CS	BRPF3 CREBBP EP300	8.58e-05	26	62	3	IPR018359
Domain	Nuc_rcpt_coact	CREBBP EP300	1.61e-04	6	62	2	IPR009110
Domain	BROMODOMAIN_1	BRPF3 CREBBP EP300	2.50e-04	37	62	3	PS00633
Domain	Bromodomain	BRPF3 CREBBP EP300	2.71e-04	38	62	3	PF00439
Domain	BROMODOMAIN_2	BRPF3 CREBBP EP300	3.39e-04	41	62	3	PS50014
Domain	BROMO	BRPF3 CREBBP EP300	3.65e-04	42	62	3	SM00297
Domain	Bromodomain	BRPF3 CREBBP EP300	3.65e-04	42	62	3	IPR001487
Domain	-	BRPF3 CREBBP EP300	3.65e-04	42	62	3	1.20.920.10
Domain	ZZ	CREBBP EP300	1.60e-03	18	62	2	PF00569
Domain	ZF_ZZ_2	CREBBP EP300	1.60e-03	18	62	2	PS50135
Domain	ZF_ZZ_1	CREBBP EP300	1.60e-03	18	62	2	PS01357
Domain	Znf_ZZ	CREBBP EP300	1.79e-03	19	62	2	IPR000433
Domain	ZnF_ZZ	CREBBP EP300	1.79e-03	19	62	2	SM00291
Domain	EPHD	BRPF3 PHF6	2.40e-03	22	62	2	PS51805
Domain	C2H2_Znf_fam	ZNF131 ZNF518B	2.85e-03	24	62	2	IPR027775
Domain	zf-C2H2_6	ZNF573 ZNF658 ZNF611 ZFP28 ZNF615	3.85e-03	314	62	5	PF13912
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	BRPF3 ZNF573 ZNF585A ZNF484 ZNF658 HIPK1 ZNF611 HIPK2 ZFP28 ZNF615 ZSCAN25 ZNF454 CREBBP PCGF5 EP300 PPM1A ZNF585B	3.56e-07	1387	44	17	M734
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	ZNF131 HIPK2 CREBBP EP300	1.02e-05	44	44	4	M27295
Pathway	BIOCARTA_PITX2_PATHWAY	TRRAP CREBBP EP300	1.26e-05	15	44	3	MM1439
Pathway	BIOCARTA_PITX2_PATHWAY	TRRAP CREBBP EP300	1.54e-05	16	44	3	M8516
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	BRPF3 ZNF585A HIPK1 HIPK2 ZFP28 ZSCAN25 ZNF454 PCGF5 EP300 PPM1A ZNF585B	1.71e-05	768	44	11	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	BRPF3 ERCC6 ZNF585A HIPK1 HIPK2 ZFP28 ZSCAN25 ZNF454 PCGF5 EP300 PPM1A ZNF585B	4.74e-05	1022	44	12	MM15436
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	IKZF1 CREBBP EP300	6.22e-05	25	44	3	M27880
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	9.46e-05	5	44	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	9.46e-05	5	44	2	M48020
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	9.46e-05	5	44	2	M27228
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	9.46e-05	5	44	2	M48023
Pathway	WP_MIR222_IN_EXERCISEINDUCED_CARDIAC_GROWTH	HIPK1 HIPK2	9.46e-05	5	44	2	MM15988
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	1.42e-04	6	44	2	M22062
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	HIPK2 PCGF5 EP300	1.59e-04	34	44	3	MM15531
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	1.98e-04	7	44	2	MM1573
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	HIPK2 PCGF5 EP300	2.05e-04	37	44	3	M27797
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	ZNF131 HIPK2 EP300	2.59e-04	40	44	3	MM15000
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	2.63e-04	8	44	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	2.63e-04	8	44	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	2.63e-04	8	44	2	M48024
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	2.63e-04	8	44	2	M46443
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	3.38e-04	9	44	2	M47451
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	CREBBP EP300	4.22e-04	10	44	2	M27945
Pathway	REACTOME_SIGNALING_BY_NOTCH3	IKZF1 CREBBP EP300	4.73e-04	49	44	3	M618
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	5.14e-04	11	44	2	MM1521
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300	5.14e-04	11	44	2	M48021
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	5.14e-04	11	44	2	M26924
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	6.16e-04	12	44	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	6.16e-04	12	44	2	M27765
Pathway	PID_P53_REGULATION_PATHWAY	HIPK2 CREBBP EP300	8.16e-04	59	44	3	M261
Pathway	REACTOME_PHYSIOLOGICAL_FACTORS	HIPK1 HIPK2	8.46e-04	14	44	2	M27459
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP EP300	8.46e-04	14	44	2	M27808
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	9.74e-04	15	44	2	MM1339
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	9.74e-04	15	44	2	M10183
Pathway	KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27	PCGF5 EP300	9.74e-04	15	44	2	M47973
Pathway	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	HIPK1 HIPK2	9.74e-04	15	44	2	M603
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP EP300	9.74e-04	15	44	2	M953
Pathway	REACTOME_HATS_ACETYLATE_HISTONES	BRPF3 TRRAP CREBBP EP300	9.80e-04	142	44	4	M27233
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.11e-03	16	44	2	M1296
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.11e-03	16	44	2	MM1420
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP EP300	1.11e-03	16	44	2	M27121
Pathway	WP_BDNF_PATHWAY	LPA NTRK2	1.11e-03	16	44	2	MM15816
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES	CREBBP EP300	1.11e-03	16	44	2	M27940
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	1.26e-03	17	44	2	MM1509
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	CREBBP EP300	1.26e-03	17	44	2	M48025
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	CREBBP EP300	1.41e-03	18	44	2	M26942
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	BRPF3 HIPK1 HIPK2 EP300	1.42e-03	157	44	4	MM15226
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	BRPF3 TRRAP CREBBP UTY EP300	1.51e-03	272	44	5	M29619
Pathway	PID_E2F_PATHWAY	TRRAP CREBBP EP300	1.52e-03	73	44	3	M40
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	BRPF3 HIPK1 HIPK2 EP300	1.52e-03	160	44	4	M27498
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	1.57e-03	19	44	2	M18933
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	CREBBP EP300	1.57e-03	19	44	2	M46442
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	1.75e-03	20	44	2	M27881
Pathway	PID_MYC_ACTIV_PATHWAY	TRRAP CREBBP EP300	1.90e-03	79	44	3	M66
Pathway	WP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX	CREBBP EP300	1.93e-03	21	44	2	M39593
Pathway	REACTOME_CD209_DC_SIGN_SIGNALING	CREBBP EP300	1.93e-03	21	44	2	M27485
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300	2.11e-03	22	44	2	MM1443
Pathway	BIOCARTA_VDR_PATHWAY	CREBBP EP300	2.11e-03	22	44	2	MM1370
Pathway	PID_CMYB_PATHWAY	HIPK2 CREBBP EP300	2.27e-03	84	44	3	M195
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300	2.31e-03	23	44	2	M2821
Pathway	BIOCARTA_VDR_PATHWAY	CREBBP EP300	2.52e-03	24	44	2	M13404
Pathway	REACTOME_SUMOYLATION	ZNF131 HIPK2 CREBBP EP300	2.80e-03	189	44	4	M27214
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	TRRAP CREBBP EP300	2.85e-03	91	44	3	M27101
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	ZMIZ1 CREBBP EP300	2.85e-03	91	44	3	M39700
Pathway	BIOCARTA_CARM_ER_PATHWAY	CREBBP EP300	2.95e-03	26	44	2	M2499
Pathway	PID_HDAC_CLASSIII_PATHWAY	CREBBP EP300	2.95e-03	26	44	2	M32
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	TRRAP EP300	2.95e-03	26	44	2	MM14793
Pathway	REACTOME_ATTENUATION_PHASE	CREBBP EP300	3.42e-03	28	44	2	M27254
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	BRPF3 EP300	3.66e-03	29	44	2	MM15340
Pathway	PID_RETINOIC_ACID_PATHWAY	CREBBP EP300	3.92e-03	30	44	2	M207
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	BRPF3 EP300	3.92e-03	30	44	2	M27637
Pathway	REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION	ERCC6 EP300	3.92e-03	30	44	2	MM15173
Pathway	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	CREBBP EP300	3.92e-03	30	44	2	M936
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CREBBP EP300	4.45e-03	32	44	2	M39521
Pathway	WP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA	CREBBP EP300	5.01e-03	34	44	2	M39771
Pathway	PID_HIF2PATHWAY	CREBBP EP300	5.01e-03	34	44	2	M44
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53	BRPF3 HIPK1 HIPK2 CREBBP EP300	5.07e-03	360	44	5	M27267
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	CREBBP EP300	5.31e-03	35	44	2	M48246
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	6.23e-03	38	44	2	M27757
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	CREBBP EP300	6.23e-03	38	44	2	M27255
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	HIPK2 CREBBP PCGF5 EP300	6.24e-03	237	44	4	M27786
Pathway	REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS	CREBBP EP300 MEIS1	6.47e-03	122	44	3	M29689
Pubmed	Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.	HIPK1 HIPK2 EP300	1.13e-07	6	63	3	16917507
Pubmed	Human ING1 proteins differentially regulate histone acetylation.	TRRAP CREBBP EP300	1.97e-07	7	63	3	12015309
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF585A ZFP28 ZNF585B	1.97e-07	7	63	3	3143103
Pubmed	Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression.	HIPK1 HIPK2 IKZF1	4.72e-07	9	63	3	16940173
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	3.23e-06	2	63	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	3.23e-06	2	63	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	3.23e-06	2	63	2	19729597
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	3.23e-06	2	63	2	37668106
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	3.23e-06	2	63	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	3.23e-06	2	63	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	3.23e-06	2	63	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	3.23e-06	2	63	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	3.23e-06	2	63	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	3.23e-06	2	63	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	3.23e-06	2	63	2	30135524
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	3.23e-06	2	63	2	39287984
Pubmed	Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.	HIPK1 HIPK2	3.23e-06	2	63	2	20231426
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	3.23e-06	2	63	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	3.23e-06	2	63	2	29217654
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	3.23e-06	2	63	2	20717166
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	3.23e-06	2	63	2	10049825
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	3.23e-06	2	63	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	3.23e-06	2	63	2	29170789
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	3.23e-06	2	63	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	3.23e-06	2	63	2	11559821
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	3.23e-06	2	63	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	3.23e-06	2	63	2	12646247
Pubmed	p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function.	HIPK2 EP300	3.23e-06	2	63	2	29170424
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	3.23e-06	2	63	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	3.23e-06	2	63	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	3.23e-06	2	63	2	24522976
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	3.23e-06	2	63	2	11867645
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	3.23e-06	2	63	2	21847097
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	3.23e-06	2	63	2	11963968
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	3.23e-06	2	63	2	34813504
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	3.23e-06	2	63	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	3.23e-06	2	63	2	12696060
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	3.23e-06	2	63	2	20301699
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	3.23e-06	2	63	2	36109165
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	3.23e-06	2	63	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	3.23e-06	2	63	2	37816914
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	3.23e-06	2	63	2	12242694
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	3.23e-06	2	63	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	3.23e-06	2	63	2	10918613
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	3.23e-06	2	63	2	31182547
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	3.23e-06	2	63	2	35502657
Pubmed	Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.	CREBBP EP300	3.23e-06	2	63	2	30635043
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	3.23e-06	2	63	2	31898871
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	3.23e-06	2	63	2	27648933
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	3.23e-06	2	63	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	3.23e-06	2	63	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	3.23e-06	2	63	2	19272189
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	3.23e-06	2	63	2	10610021
Pubmed	Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.	CREBBP EP300	3.23e-06	2	63	2	37314181
Pubmed	Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.	CREBBP EP300	3.23e-06	2	63	2	12397173
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	3.23e-06	2	63	2	15641773
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	3.23e-06	2	63	2	32690000
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.	CREBBP EP300	3.23e-06	2	63	2	9733868
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	3.23e-06	2	63	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	3.23e-06	2	63	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	3.23e-06	2	63	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	3.23e-06	2	63	2	24089570
Pubmed	Rubinstein-Taybi syndrome in Chinese population with four novel mutations.	CREBBP EP300	3.23e-06	2	63	2	33063428
Pubmed	EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.	CREBBP EP300	3.23e-06	2	63	2	34506759
Pubmed	Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.	CREBBP EP300	3.23e-06	2	63	2	22177454
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	3.23e-06	2	63	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	3.23e-06	2	63	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	3.23e-06	2	63	2	22303793
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	3.23e-06	2	63	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	3.23e-06	2	63	2	34019788
Pubmed	NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.	CREBBP PCGF5 EP300	3.78e-06	17	63	3	34637754
Pubmed	Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.	TRRAP CREBBP EP300	3.78e-06	17	63	3	12464179
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF585A ZNF185 ZFP28 IKZF1 ZBTB1 CREBBP PLXNA1 MEIS1 ZNF585B	5.12e-06	709	63	9	22988430
Pubmed	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.	CREBBP EP300	9.68e-06	3	63	2	14716005
Pubmed	The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.	CREBBP EP300	9.68e-06	3	63	2	18070920
Pubmed	The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.	CREBBP EP300	9.68e-06	3	63	2	21967847
Pubmed	CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.	CREBBP EP300	9.68e-06	3	63	2	19252086
Pubmed	Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.	CREBBP EP300	9.68e-06	3	63	2	27903646
Pubmed	Inhibition of p300/CBP by early B-cell factor.	CREBBP EP300	9.68e-06	3	63	2	12748286
Pubmed	p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.	CREBBP EP300	9.68e-06	3	63	2	10075656
Pubmed	Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.	CREBBP EP300	9.68e-06	3	63	2	24340053
Pubmed	Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.	CREBBP EP300	9.68e-06	3	63	2	19273602
Pubmed	Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.	CREBBP EP300	9.68e-06	3	63	2	15649887
Pubmed	Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.	CREBBP EP300	9.68e-06	3	63	2	22179676
Pubmed	CBP/p300 are bimodal regulators of Wnt signaling.	CREBBP EP300	9.68e-06	3	63	2	17410209
Pubmed	DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.	CREBBP EP300	9.68e-06	3	63	2	26951377
Pubmed	CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.	CREBBP EP300	9.68e-06	3	63	2	21789216
Pubmed	Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.	CREBBP EP300	9.68e-06	3	63	2	12050117
Pubmed	Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.	CREBBP EP300	9.68e-06	3	63	2	16237459
Pubmed	A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.	CREBBP EP300	9.68e-06	3	63	2	12384703
Pubmed	Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.	CREBBP EP300	9.68e-06	3	63	2	10350644
Pubmed	Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.	CREBBP EP300	9.68e-06	3	63	2	29145650
Pubmed	Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.	CREBBP EP300	9.68e-06	3	63	2	7870179
Pubmed	The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.	CREBBP EP300	9.68e-06	3	63	2	19041714
Pubmed	Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.	HIPK2 CREBBP	9.68e-06	3	63	2	11740489
Pubmed	Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.	CREBBP EP300	9.68e-06	3	63	2	12776737
Pubmed	Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.	CREBBP EP300	9.68e-06	3	63	2	30836930
Pubmed	Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.	CREBBP EP300	9.68e-06	3	63	2	14759370
Pubmed	Activation of Smad1-mediated transcription by p300/CBP.	CREBBP EP300	9.68e-06	3	63	2	10673036
Pubmed	Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.	CREBBP EP300	9.68e-06	3	63	2	12456660
Interaction	HOXD4 interactions	HIPK1 CREBBP EP300 MEIS1	2.24e-06	30	63	4	int:HOXD4
Interaction	HOXB4 interactions	CREBBP EP300 MEIS1	3.72e-05	21	63	3	int:HOXB4
Interaction	HOXA10 interactions	BRPF3 CREBBP EP300 MEIS1	4.22e-05	62	63	4	int:HOXA10
Interaction	FOXO3 interactions	HIPK2 TRRAP CREBBP EP300 PPM1A	4.30e-05	124	63	5	int:FOXO3
Interaction	NR6A1 interactions	TRRAP CREBBP EP300	5.62e-05	24	63	3	int:NR6A1
Interaction	MYB interactions	ZNF131 HIPK2 PHF6 CREBBP EP300	6.00e-05	133	63	5	int:MYB
Interaction	RUNX1 interactions	ZNF131 HIPK1 HIPK2 IKZF1 CREBBP PCGF5 EP300	6.65e-05	324	63	7	int:RUNX1
Cytoband	Ensembl 112 genes in cytogenetic band chr14q23	ZBTB25 GPR135 CHURC1 ZBTB1 PPM1A GPHB5	2.73e-08	130	63	6	chr14q23
Cytoband	19q13.12	ZNF573 ZNF585A ZNF585B	1.37e-04	72	63	3	19q13.12
Cytoband	14q23.3	CHURC1 ZBTB1	5.90e-04	26	63	2	14q23.3
Cytoband	14q23.1	GPR135 PPM1A	1.93e-03	47	63	2	14q23.1
Cytoband	22q12.2	PLA2G3 PRR14L	2.92e-03	58	63	2	22q12.2
Cytoband	19q13.41	ZNF611 ZNF615	5.20e-03	78	63	2	19q13.41
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF573 ZNF585A ZNF611 ZFP28 ZNF615 ZNF585B	5.84e-03	1192	63	6	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF131 CTCFL ZNF573 ZNF585A ZNF484 ZNF658 ZBTB25 ZNF611 ZFP28 IKZF1 ZNF518B ZNF615 ZSCAN25 ZNF454 ZBTB1 CASZ1 ZNF585B	2.49e-12	718	49	17	28
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	9.53e-04	17	49	2	486
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.07e-03	18	49	2	91
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PTPRK PLA2G3 ZNF385B ZNF518B ZNF615 ZSCAN25 MEIS1	3.81e-09	166	63	7	89e2b8453180983533faccb4275867861876d7ee
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|356C / Donor, Lineage, Cell class and subclass (all cells)	PLA2G3 ZNF518B ZNF615 ZSCAN25 MEIS1	3.08e-06	159	63	5	24f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PTPRK PLA2G3 ZNF385B ZNF518B MEIS1	3.38e-06	162	63	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHF6 ZBTB1 ACBD3 PLXNA1 CASZ1	5.80e-06	181	63	5	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	NBEAL1 PHF6 CHURC1 CREBBP EP300	6.62e-06	186	63	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm\|5w / Sample Type, Dataset, Time_group, and Cell type.	ERCC6 GNE ZSCAN25 EP300 PLEKHM1	9.41e-06	200	63	5	0927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GNE ADAMTS17 CASZ1 MEIS1 DOP1B	9.41e-06	200	63	5	85c0f038bcfb42669dca2b80273b0f8a1421405e
Disease	Menke-Hennekam syndrome	CREBBP EP300	4.20e-06	2	61	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	4.20e-06	2	61	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	4.20e-06	2	61	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	4.20e-06	2	61	2	C4551859
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	4.20e-06	2	61	2	180849
Disease	Abnormality of the urinary system	ZMIZ1 TRRAP	4.20e-06	2	61	2	C4021821
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	4.20e-06	2	61	2	cv:C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	4.20e-06	2	61	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	4.20e-06	2	61	2	C0035934
Disease	Diamond-Blackfan anemia (implicated_via_orthology)	RPS26P11 RPS26	1.87e-04	10	61	2	DOID:1339 (implicated_via_orthology)
Disease	Diffuse Large B-Cell Lymphoma	IKZF1 CREBBP EP300	2.04e-04	55	61	3	C0079744
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	IKZF1 CREBBP EP300	2.78e-04	61	61	3	C1961102
Disease	Microcephaly	ERCC6 ZMIZ1 TRRAP	3.66e-04	67	61	3	C0025958
Disease	lymphocyte count	ZNF131 SLFN12L PCDHGB3 ZBTB25 IKZF1 RPS26 ZSCAN25 ZMIZ1 ZBTB1 CASZ1	7.83e-04	1464	61	10	EFO_0004587
Disease	idiopathic pulmonary fibrosis (is_marker_for)	NTRK2 EP300	1.03e-03	23	61	2	DOID:0050156 (is_marker_for)
Disease	Carcinoma of lung	ERCC6 NTRK2	1.03e-03	23	61	2	C0684249
Disease	congestive heart failure (is_implicated_in)	PHF6 EP300	1.43e-03	27	61	2	DOID:6000 (is_implicated_in)
Disease	Stevens-Johnson Syndrome	IKZF1 EP300	1.76e-03	30	61	2	C0038325
Disease	colorectal cancer (is_implicated_in)	ERCC6 IKZF1 EP300	2.04e-03	121	61	3	DOID:9256 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FVYTCNECKHHVETR	EP300	1666	Q09472
KPYECHICHTRFTQS	CTCFL	396	Q8NI51
SHIYEKQDRCCHKTV	ALPK2	221	Q86TB3
AACQFSLKVTHYHCT	CASZ1	1446	Q86V15
RFKEQEYSTEHHLVC	ASB4	221	Q9Y574
RYCMERASVHCAHVF	GYS2	241	P54840
DRFVYTCNECKHHVE	CREBBP	1701	Q92793
AIQCHKVNCYTAFHV	BRPF3	336	Q9ULD4
TCEKGFQHREVTCVY	ADAMTS17	876	Q8TE56
HCVCVTKEYSHILVG	NBEAL1	2631	Q6ZS30
KVHELCDNFCHRYIS	MEIS1	161	O00470
CDVALHVKCSVEYHT	ERCC6	1046	P0DP91
HTFCKTCIVQHFEDS	PCGF5	36	Q86SE9
VRAYECFQHKNHTCL	HIPK2	261	Q9H2X6
CSRIQEFCEQHYHCA	TAT	431	P17735
FVRSYECFQHKNHTC	HIPK1	251	Q86Z02
KETREHHVTCVELFY	DOP1B	886	Q9Y3R5
KYRHVCTHNVADCAF	PLXNA1	681	Q9UIW2
YCKSHVITRAFCLHQ	OR51B2	166	Q9Y5P1
NRCCHLFSTYVASHK	ACBD3	166	Q9H3P7
VYKCEHCRVLFLDHV	IKZF1	461	Q13422
HHTAYCKVQIDISDE	PCDHGB3	326	Q9Y5G1
CHYHICKTVRLSDVR	GPR135	296	Q8IZ08
TKLAHYHVCCTRSAE	GNE	151	Q9Y223
YHVCCTRSAEQHLIS	GNE	156	Q9Y223
YIEAHHRVCTYNETK	GPHB5	76	Q86YW7
EVCNHYKYICAEHLA	LPA	1966	P08519
SEHCEQEVAYHCRRS	CNTNAP5	671	Q8WYK1
ITKYENAFQHRDHCC	PRR14L	821	Q5THK1
NITRCHTFNVTICYH	PTPRK	416	Q15262
KIIHHYVSSCQDICL	MROH2A	806	A6NES4
IEFASQHVYHCDLCT	PLEKHM1	981	Q9Y4G2
NTQKTYIVHCHDCAR	UTY	1296	O14607
RNYRFHTISHCDCDT	PLA2G3	201	Q9NZ20
CKNCHHVIARHEYTF	CHURC1	61	Q8WUH1
CTKIHVTNHTEYHGC	NTRK2	331	Q16620
TENSVKIHLCHYCGE	ZBTB25	231	P24278
QRTHTELKHYECTEC	ZNF615	251	Q8N8J6
YECDVCRKAFSHHAS	ZFP28	561	Q8NHY6
TIGCDVKTCHRTYHY	PHF6	91	Q8IWS0
TVHQRFHTGEKTYEC	ZNF573	206	Q86YE8
VHHFCVEKGTINYLC	SLFN12L	291	Q6IEE8
LHYCVSCAIHSKVVR	RPS26P11	71	Q5JNZ5
QVAKYCCEHLLDHIT	PPM1A	66	P35813
HQRTHEEKSYGCVEC	ZSCAN25	366	Q6NSZ9
QKIHTGERQYECHEC	ZNF585B	541	Q52M93
KTFHCEICDVHVNSE	ZNF385B	346	Q569K4
QKIHTGERQYECHEC	ZNF585A	541	Q6P3V2
SSHYLAKHIENICAC	ZBTB1	436	Q9Y2K1
YECVECEKTFSHKTH	ZNF658	546	Q5TYW1
SYVECCRTQEHAHSE	YAE1	181	Q9NRH1
IHQKCHTGERHYECS	ZNF484	541	Q5JVG2
YECRECGKAFHQSTH	ZNF454	216	Q8N9F8
EQYLACHDRCHTVEK	ZNF611	271	Q8N823
LHYCVSCAIHSKVVR	RPS26	71	P62854
KIHVCQYCEKQFDHF	ZNF131	326	P52739
HIQTYCEVSVDGHKC	WDR31	231	Q8NA23
TCYLHACRHQNESKS	TRRAP	3181	Q9Y4A5
QIFIHRDTIHCGKCY	ZNF185	671	O15231
RPEECDCHKISYHTQ	SULF2	656	Q8IWU5
HLYICHTCQIEAEKI	USP33	806	Q8TEY7
HDCKHVQCFDLESYL	ZMIZ1	756	Q9ULJ6
QHEEIKFICSHCSYI	ZNF518B	156	Q9C0D4
YECVECEKTFSHKTH	ZNF658B	306	Q4V348