Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K27 trimethyltransferase activity	EZH1 EZH2	1.92e-05	3	51	2	GO:0140951
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	EZH1 EZH2	9.53e-05	6	51	2	GO:0046976
GeneOntologyBiologicalProcess	hepatocyte homeostasis	EZH1 EZH2	5.76e-06	2	50	2	GO:0036333
GeneOntologyBiologicalProcess	response to tetrachloromethane	EZH1 EZH2	5.73e-05	5	50	2	GO:1904772
Domain	EZH2_WD-Binding	EZH1 EZH2	7.31e-06	2	51	2	PF11616
Domain	EZH1/EZH2	EZH1 EZH2	7.31e-06	2	51	2	IPR021654
Domain	CXC_dom	EZH1 EZH2	7.31e-06	2	51	2	IPR026489
Domain	CXC	EZH1 EZH2	7.31e-06	2	51	2	PS51633
Domain	Znf_CCCH	MBNL2 MBNL1 ZC3H12D MBNL3	1.88e-05	58	51	4	IPR000571
Domain	ZF_C3H1	MBNL2 MBNL1 ZC3H12D MBNL3	1.88e-05	58	51	4	PS50103
Domain	Tesmin/TSO1-like_CXC	EZH1 EZH2	1.09e-04	6	51	2	IPR033467
Domain	CXC	EZH1 EZH2	1.09e-04	6	51	2	SM01114
Domain	RNase_Zc3h12a	KHNYN ZC3H12D	1.52e-04	7	51	2	PF11977
Domain	RNase_Zc3h12_NYN	KHNYN ZC3H12D	1.52e-04	7	51	2	IPR021869
Domain	-	MBNL2 MBNL1 MBNL3	1.76e-04	40	51	3	4.10.1000.10
Domain	ZnF_C3H1	MBNL2 MBNL1 MBNL3	3.04e-04	48	51	3	SM00356
Domain	zf-CCCH	MBNL2 MBNL1 MBNL3	3.23e-04	49	51	3	PF00642
Domain	RICIN	GALNT14 PLA2R1	2.64e-03	28	51	2	SM00458
Domain	RICIN_B_LECTIN	GALNT14 PLA2R1	2.64e-03	28	51	2	PS50231
Domain	Ricin_B_lectin	GALNT14 PLA2R1	3.03e-03	30	51	2	IPR000772
Domain	JMJC	KDM5B JMJD7	3.44e-03	32	51	2	PS51184
Domain	JmjC_dom	KDM5B JMJD7	3.44e-03	32	51	2	IPR003347
Domain	JmjC	KDM5B JMJD7	3.66e-03	33	51	2	SM00558
Domain	SET	EZH1 EZH2	5.60e-03	41	51	2	PF00856
Domain	SET	EZH1 EZH2	7.01e-03	46	51	2	SM00317
Domain	P-loop_NTPase	MPP2 SAMD9L MYO5A ARHGAP35 OLA1 AQR SMC1B	7.87e-03	848	51	7	IPR027417
Domain	SET_dom	EZH1 EZH2	8.24e-03	50	51	2	IPR001214
Domain	SANT	EZH1 EZH2	8.24e-03	50	51	2	SM00717
Domain	SET	EZH1 EZH2	8.24e-03	50	51	2	PS50280
Domain	SANT/Myb	EZH1 EZH2	8.88e-03	52	51	2	IPR001005
Pubmed	Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	19095965
Pubmed	Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	32332745
Pubmed	Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	11929853
Pubmed	Muscleblind proteins regulate alternative splicing.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	15257297
Pubmed	Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	28698297
Pubmed	Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.	MBNL2 MBNL1 MBNL3	2.97e-09	3	51	3	25263597
Pubmed	Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation.	MBNL2 MBNL1 MBNL3	1.19e-08	4	51	3	26501102
Pubmed	Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.	MBNL2 MBNL1 MBNL3	1.19e-08	4	51	3	12915312
Pubmed	MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.	MBNL2 MBNL1 MBNL3	5.92e-08	6	51	3	19720736
Pubmed	Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.	MBNL2 MBNL1 MBNL3	6.47e-07	12	51	3	37143315
Pubmed	Distal Alternative Last Exons Localize mRNAs to Neural Projections.	MBNL2 MBNL1	2.11e-06	2	51	2	26907613
Pubmed	Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy.	MBNL2 MBNL1	2.11e-06	2	51	2	35567413
Pubmed	The competitive mechanism of EZH1 and EZH2 in promoting oral squamous cell carcinoma.	EZH1 EZH2	2.11e-06	2	51	2	38309675
Pubmed	MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.	MBNL2 MBNL1	2.11e-06	2	51	2	23739326
Pubmed	Compound loss of muscleblind-like function in myotonic dystrophy.	MBNL2 MBNL1	2.11e-06	2	51	2	24293317
Pubmed	Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.	EZH1 EZH2	2.11e-06	2	51	2	32428001
Pubmed	Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.	EZH1 EZH2	2.11e-06	2	51	2	9214638
Pubmed	PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.	EZH1 EZH2	2.11e-06	2	51	2	28939884
Pubmed	Alternative splicing mediates the compensatory upregulation of MBNL2 upon MBNL1 loss-of-function.	MBNL2 MBNL1	2.11e-06	2	51	2	36617982
Pubmed	FOXM1-Dependent Transcriptional Regulation of EZH2 Induces Proliferation and Progression in Prostate Cancer.	FOXM1 EZH2	2.11e-06	2	51	2	32735528
Pubmed	EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.	EZH1 EZH2	2.11e-06	2	51	2	21317239
Pubmed	Aberrant differential expression of EZH1 and EZH2 in Polycomb repressive complex 2 among B- and T/NK-cell neoplasms.	EZH1 EZH2	2.11e-06	2	51	2	27311868
Pubmed	MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain.	MBNL2 MBNL1	2.11e-06	2	51	2	26257173
Pubmed	Optical Mapping Approaches on Muscleblind-Like Compound Knockout Mice for Understanding Mechanistic Insights Into Ventricular Arrhythmias in Myotonic Dystrophy.	MBNL2 MBNL1	2.11e-06	2	51	2	28416514
Pubmed	Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.	EZH1 EZH2	2.11e-06	2	51	2	8921387
Pubmed	Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells.	MBNL2 MBNL1	2.11e-06	2	51	2	29735517
Pubmed	Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.	EZH1 EZH2	2.11e-06	2	51	2	25578878
Pubmed	The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration.	EZH1 EZH2	2.11e-06	2	51	2	25477280
Pubmed	Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration.	MBNL2 MBNL1	2.11e-06	2	51	2	38473933
Pubmed	EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.	EZH1 EZH2	2.11e-06	2	51	2	30522506
Pubmed	Increased Muscleblind levels by chloroquine treatment improve myotonic dystrophy type 1 phenotypes in in vitro and in vivo models.	MBNL2 MBNL1	2.11e-06	2	51	2	31754023
Pubmed	Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy.	MBNL2 MBNL1	2.11e-06	2	51	2	29331264
Pubmed	Mbnl1 and Mbnl2 regulate brain structural integrity in mice.	MBNL2 MBNL1	2.11e-06	2	51	2	34848815
Pubmed	The role of EZH1 and EZH2 in development and cancer.	EZH1 EZH2	2.11e-06	2	51	2	36476271
Pubmed	Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.	MBNL2 MBNL1	2.11e-06	2	51	2	20098426
Pubmed	Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2.	EZH1 EZH2	2.11e-06	2	51	2	9473645
Pubmed	Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins.	MBNL2 MBNL1	2.11e-06	2	51	2	22901804
Pubmed	Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.	EZH1 EZH2	2.11e-06	2	51	2	31747604
Pubmed	Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.	EZH1 EZH2	2.11e-06	2	51	2	27526204
Pubmed	The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.	EZH1 EZH2	2.11e-06	2	51	2	10051331
Pubmed	EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.	EZH1 EZH2	2.11e-06	2	51	2	30867289
Pubmed	Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2.	MBNL2 MBNL1	2.11e-06	2	51	2	24440524
Pubmed	EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy.	EZH1 EZH2	2.11e-06	2	51	2	27897169
Pubmed	Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.	MBNL1 MBNL3	2.11e-06	2	51	2	10970838
Pubmed	Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.	EZH1 EZH2	2.11e-06	2	51	2	30689973
Pubmed	Conserved developmental alternative splicing of muscleblind-like (MBNL) transcripts regulates MBNL localization and activity.	MBNL2 MBNL1	2.11e-06	2	51	2	20009516
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	LIG3 KDM5B EZH1 EZH2 BIRC6 GTF3C4 AQR	5.38e-06	469	51	7	27634302
Pubmed	Signaling function of PRC2 is essential for TCR-driven T cell responses.	EZH1 EZH2	6.32e-06	3	51	2	29523590
Pubmed	Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts.	EZH1 EZH2	6.32e-06	3	51	2	27823969
Pubmed	Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.	EZH1 EZH2	6.32e-06	3	51	2	30396150
Pubmed	Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.	MBNL2 MBNL1	6.32e-06	3	51	2	27063795
Pubmed	Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner.	EZH1 EZH2	6.32e-06	3	51	2	26219303
Pubmed	The polycomb-group gene Ezh2 is required for early mouse development.	EZH1 EZH2	6.32e-06	3	51	2	11390661
Pubmed	Chronic Myelogenous Leukemia- Initiating Cells Require Polycomb Group Protein EZH2.	EZH1 EZH2	6.32e-06	3	51	2	27630126
Pubmed	RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1.	MBNL2 MBNL1	6.32e-06	3	51	2	16273094
Pubmed	Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.	EZH1 EZH2	6.32e-06	3	51	2	22042701
Pubmed	Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells.	EZH1 EZH2	6.32e-06	3	51	2	23673358
Pubmed	Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.	MBNL2 MBNL1	6.32e-06	3	51	2	26339785
Pubmed	Long non-coding RNA FOXP4-AS1 facilitates the biological functions of hepatocellular carcinoma cells via downregulating ZC3H12D by mediating H3K27me3 through recruitment of EZH2.	ZC3H12D EZH2	6.32e-06	3	51	2	34545456
Pubmed	Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.	EZH1 EZH2	1.26e-05	4	51	2	23932971
Pubmed	Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.	EZH1 EZH2	1.26e-05	4	51	2	37105173
Pubmed	EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.	EZH1 EZH2	1.26e-05	4	51	2	19026780
Pubmed	Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.	EZH1 EZH2	1.26e-05	4	51	2	19026781
Pubmed	HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer.	FOXM1 EZH2	1.26e-05	4	51	2	27303043
Pubmed	Regulation of embryonic haematopoietic multipotency by EZH1.	EZH1 EZH2	1.26e-05	4	51	2	29342143
Pubmed	Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.	EZH1 EZH2	1.26e-05	4	51	2	31189531
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	THOP1 ZSCAN4 FARP1 MBNL1 OSBPL9 BIRC6	1.50e-05	363	51	6	14691545
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5B EZH1 EZH2	1.57e-05	33	51	3	26864203
Pubmed	miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models.	MBNL2 MBNL1	2.10e-05	5	51	2	29946070
Pubmed	Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy.	MBNL2 MBNL1	2.10e-05	5	51	2	33503262
Pubmed	A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.	EZH1 EZH2	2.10e-05	5	51	2	28320739
Pubmed	NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.	MBNL2 MBNL1	2.10e-05	5	51	2	25168381
Pubmed	PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.	EZH1 EZH2	2.10e-05	5	51	2	32820269
Pubmed	Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.	EZH1 EZH2	2.10e-05	5	51	2	9584197
Pubmed	Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing.	MBNL2 MBNL1	3.15e-05	6	51	2	16946708
Pubmed	A protein interaction landscape of breast cancer.	MYO5A RIN2 PIP4K2C OLA1 EZH1 EZH2 GTF3C4	3.74e-05	634	51	7	34591612
Pubmed	Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice.	MBNL1 MBNL3	4.41e-05	7	51	2	23660517
Pubmed	Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.	ZC3H12D MBNL3	4.41e-05	7	51	2	18682727
Pubmed	X chromosome reactivation and regulation in cloned embryos.	EZH1 EZH2	4.41e-05	7	51	2	15733677
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	THOP1 MYO5A UBE4B MBNL2 FARP1 RIN2 MBNL1 OSBPL9 ARHGAP35 CFAP69	5.15e-05	1489	51	10	28611215
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM5B EZH1 EZH2	5.22e-05	49	51	3	34368113
Pubmed	Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer.	FOXM1 EZH2	5.87e-05	8	51	2	31661141
Pubmed	Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles.	EZH1 EZH2	5.87e-05	8	51	2	38419656
Pubmed	Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.	EZH1 EZH2	5.87e-05	8	51	2	20144788
Pubmed	New insights into BS69 functions.	EZH1 EZH2	5.87e-05	8	51	2	16565076
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	ZFAND2A MYO5A UBE4B PIK3C2B KHNYN OLA1	7.21e-05	481	51	6	28190767
Pubmed	PRC2 directly methylates GATA4 and represses its transcriptional activity.	EZH1 EZH2	7.54e-05	9	51	2	22215809
Pubmed	EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.	EZH1 EZH2	7.54e-05	9	51	2	28254491
Pubmed	Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis.	EZH1 EZH2	7.54e-05	9	51	2	37435868
Pubmed	JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.	EZH1 EZH2	7.54e-05	9	51	2	20075857
Pubmed	Precise temporal regulation of alternative splicing during neural development.	MBNL2 MBNL1	7.54e-05	9	51	2	29875359
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM5B EZH2 GTF3C4	8.22e-05	57	51	3	18022353
Pubmed	Neurodegeneration with Brain Iron Accumulation Disorders Overview	FA2H ATP13A2	9.42e-05	10	51	2	23447832
Pubmed	The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians.	MBNL2 MBNL3	9.42e-05	10	51	2	35476669
Pubmed	Divergent Requirements for EZH1 in Heart Development Versus Regeneration.	EZH1 EZH2	9.42e-05	10	51	2	28512107
Pubmed	EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.	EZH1 EZH2	9.42e-05	10	51	2	31451685
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	FOXM1 GALNT14 KHNYN BIRC6 KCNH5	9.57e-05	313	51	5	20800603
Pubmed	Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.	EZH1 EZH2	1.15e-04	11	51	2	22438827
Pubmed	Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise.	MBNL2 MBNL1	1.15e-04	11	51	2	22846424
Pubmed	An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.	EZH1 EZH2	1.15e-04	11	51	2	23273982
GeneFamily	Zinc fingers CCCH-type	MBNL2 MBNL1 ZC3H12D MBNL3	8.29e-07	35	38	4	73
GeneFamily	Lysine methyltransferases\|Myb/SANT domain containing\|Polycomb repressive complex 2	EZH1 EZH2	6.42e-05	6	38	2	1347
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EZH1 EZH2	2.31e-03	34	38	2	487
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	EZH1 EZH2	5.54e-03	53	38	2	532
Coexpression	MALTA_CURATED_STEMNESS_MARKERS	KDM5B ZSCAN4 EZH2	8.48e-06	21	50	3	M30411
Coexpression	GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP	ZHX3 UBE4B MBNL2 POU1F1 EZH1	3.58e-05	196	50	5	M7666
Coexpression	GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP	ZHX3 LIG3 MBNL1 CFAP69 GTF3C4	3.94e-05	200	50	5	M8975
Coexpression	GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_UP	ZHX3 UBE4B ARHGAP35 EZH1 AQR	3.94e-05	200	50	5	M6832
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#3_top-relative-expression-ranked_500	MYO5A BIRC6 MBNL3 SMC1B	3.31e-05	79	49	4	gudmap_developingGonad_P2_ovary_500_k3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA ZC3H12D EZH2 BANK1 GTF3C4	2.56e-06	190	51	5	0db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCell	Caecum-B_cell-B_cell_cycling\|Caecum / Region, Cell class and subclass	FOXM1 GALNT14 THOP1 FA2H CFAP69	3.13e-06	198	51	5	61294fe99a5641ad359796022c3d038470076b3c
ToppCell	Caecum-(2)_B_cell-(24)_B_cell_cycling\|Caecum / shred on region, Cell_type, and subtype	FOXM1 GALNT14 THOP1 FA2H CFAP69	3.13e-06	198	51	5	568d47770cd20c6569ca84ea1eafde367642d68b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	PLA2R1 KHNYN MBNL3 KCNH5	2.18e-05	143	51	4	0118772a5bc7c48465e9b314be55203412e8d67c
ToppCell	Mild/Remission-B_naive-4\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZHX3 HLA-DRA MBNL1 BANK1	2.49e-05	148	51	4	dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MPP2 THOP1 FA2H ARHGAP35	2.69e-05	151	51	4	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FSIP2 PIK3C2B HLA-DRA BANK1	3.22e-05	158	51	4	41cf950983f47a9e55d56041b301006b42853b37
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GALNT14 SAMD9L HLA-DRA BANK1	3.81e-05	165	51	4	8003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	PLA2R1 KHNYN MBNL3 KCNH5	3.99e-05	167	51	4	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZHX3 HLA-DRA MBNL1 BANK1	4.18e-05	169	51	4	c3a6179a64589a370108fea809b157839347759c
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRHDE FSIP2 HLA-DRA RIN2	4.90e-05	176	51	4	23fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PIK3C2B ZC3H12D BANK1	4.90e-05	176	51	4	9b58734017ceabe81f490dd0b9f3192bc903d455
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRHDE FSIP2 HLA-DRA RIN2	4.90e-05	176	51	4	30adf8f1638c6244586f8101c2590bb964dfae00
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PIK3C2B ZC3H12D BANK1	5.23e-05	179	51	4	de3245e1ee269e422de0308d0dd3623e4e9eb182
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PIK3C2B ZC3H12D BANK1	5.23e-05	179	51	4	c41c11171dfb40e5ddea6bf97d9373eb03a2321b
ToppCell	facs-Heart-LV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FA2H ZC3H12D B3GNT7 BANK1	5.46e-05	181	51	4	8855812c85ef45c1be6bd511619b2dfe5e441264
ToppCell	facs-Heart-LV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FA2H ZC3H12D B3GNT7 BANK1	5.46e-05	181	51	4	57f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9L HLA-DRA ZC3H12D BANK1	5.70e-05	183	51	4	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	facs-BAT-Fat-18m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D B3GNT7 BANK1	5.82e-05	184	51	4	fd72663bf990266da2fba70d4f2260f8d48067ee
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAMD9L MBNL1 BIRC6 AQR	5.82e-05	184	51	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-GAT-Fat-18m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D B3GNT7 BANK1	5.95e-05	185	51	4	1eba3b058e23a7d19024b4363dfeb522a8af313d
ToppCell	COVID-cycling-\|COVID / Condition, Cell_class and T cell subcluster	FOXM1 PLA2R1 EZH2 SMC1B	5.95e-05	185	51	4	eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCell	COVID-cycling\|COVID / Condition, Cell_class and T cell subcluster	FOXM1 PLA2R1 EZH2 SMC1B	5.95e-05	185	51	4	5112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 ZHX3 FARP1	6.07e-05	186	51	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	facs-MAT-Fat-18m-Lymphocytic-B_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D B3GNT7 BANK1	6.07e-05	186	51	4	cee9faec3fb7baa56c87592fb166d32d0bf8fe94
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 ZHX3 FARP1	6.33e-05	188	51	4	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE GALNT14 FARP1 FA2H	6.33e-05	188	51	4	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE GALNT14 PLA2R1 FARP1	6.73e-05	191	51	4	de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE GALNT14 PLA2R1 FARP1	6.87e-05	192	51	4	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MBNL2 HLA-DRA EZH2 BANK1	7.01e-05	193	51	4	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KDM5B BIRC6 GTF3C4 AQR	7.01e-05	193	51	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	(18)_cycling_gd_T\|World / shred on Cell_type and subtype	FOXM1 B3GNT7 EZH2 SMC1B	8.52e-05	203	51	4	7d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	JMJD7 PIK3C2B ARHGAP35	3.68e-04	122	51	3	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	PND01-03-samps-Lymphocyte-B_cell-B_cell_1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SAMD9L ZC3H12D BANK1	4.24e-04	128	51	3	5d82247ceda55017628720ed8b6c36ff7cec8437
ToppCell	PND01-03-samps-Lymphocyte-B_cell\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SAMD9L ZC3H12D BANK1	4.24e-04	128	51	3	7661402dd7cd533c1bfe8d9247cecd88c1be9a5e
ToppCell	PND01-03-samps-Lymphocyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SAMD9L ZC3H12D BANK1	4.24e-04	128	51	3	d3158825a2178244b57ac5ad2676617fd58d8466
ToppCell	PND07-28-samps-Lymphocyte-B_cell-B_cell_2\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PIK3C2B KHNYN BANK1	5.17e-04	137	51	3	2544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCell	PND07-28-samps-Lymphocyte-B_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PIK3C2B KHNYN BANK1	5.17e-04	137	51	3	874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-13\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIK3C2B HLA-DRA BANK1	5.97e-04	144	51	3	b2a9f3b5dd46d27689467f4a5fd717cd5827821f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FARP1 RIN2 ZC3H12D	6.60e-04	149	51	3	aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCell	P15-Hematopoietic-Immune\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZC3H12D B3GNT7 BANK1	6.86e-04	151	51	3	a54045cac65a66197e3ad2b002fa6c511102834a
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HINT3 ATP13A2 BANK1	6.86e-04	151	51	3	7270b8bbfae659e110bd9d513b602120b25de3dd
ToppCell	P15-Hematopoietic-Immune-immune_cell_unspecified\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZC3H12D B3GNT7 BANK1	6.86e-04	151	51	3	6b905d309f2a9b8828399b36f4942aec8696bee6
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PIK3C2B HLA-DRA BANK1	6.86e-04	151	51	3	0f8f07e44c6edaf09574930b416fdce14d67095a
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	FSIP2 ZC3H12D SARDH	7.12e-04	153	51	3	cda759ab83a271974651fe4faa21ed4f7ecbb3ae
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRAPPC11 HLA-DRA BANK1	7.54e-04	156	51	3	cea7b4f133272499e77ed451db91f699cff6a4bb
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	7.82e-04	158	51	3	66c011e9de002224f70725dfe8e7871c8d304492
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5A ATP13A2 BANK1	8.11e-04	160	51	3	18954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCell	facs-Trachea-nan-18m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H12D HINT3 BANK1	8.11e-04	160	51	3	5c9281706009558c8361bfa76169f43ffc0f7947
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRHDE MPP2 FA2H	8.26e-04	161	51	3	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3C2B ZC3H12D BANK1	8.26e-04	161	51	3	98be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3C2B ZC3H12D BANK1	8.26e-04	161	51	3	7af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 FARP1	8.71e-04	164	51	3	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	Int-URO-Myeloid-cDC1\|Int-URO / Disease, Lineage and Cell Type	GALNT14 OSBPL9 B3GNT7	8.71e-04	164	51	3	f4628a7ff0dc765a5337ab499b3d61fc25573a16
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 FARP1	8.71e-04	164	51	3	382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIK3C2B HLA-DRA BANK1	8.86e-04	165	51	3	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO5A ATP13A2 MBNL3	8.86e-04	165	51	3	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT7 BANK1 MBNL3	9.02e-04	166	51	3	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT7 BANK1 MBNL3	9.02e-04	166	51	3	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SAMD9L HLA-DRA BANK1	9.34e-04	168	51	3	907692c1f03d3c9889ba1bed5a4844e2c379db8e
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA CFAP69 BANK1	9.34e-04	168	51	3	ba127d97697202a8558a0d50bcdafa30b0509de1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FA2H HLA-DRA BANK1	9.50e-04	169	51	3	e3ec9468141b6456398dca17dd8eeaabd2462710
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 BANK1 GTF3C4	9.50e-04	169	51	3	b66ffc2b2b6bfcc3a6e639d9d31d3de95f4a94e1
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|390C / Donor, Lineage, Cell class and subclass (all cells)	MYO5A HLA-DRA RIN2	9.50e-04	169	51	3	2c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAPPC11 THOP1 GTF3C4	9.66e-04	170	51	3	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXM1 PIK3C2B EZH2	9.66e-04	170	51	3	e08a6c5ac34c456da8c7318f104e06fca585be1f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA MBNL1 BANK1	9.83e-04	171	51	3	a350a5f840e0fb0ccd29bb29cacc23a89abd8404
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCMBP PIK3C2B BIRC6	9.83e-04	171	51	3	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA MBNL1 BANK1	9.83e-04	171	51	3	e0a99ca8d4c86b58f54af7755ffd8e0ffbfae5e1
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B B3GNT7 BANK1	9.83e-04	171	51	3	a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B B3GNT7 BANK1	9.83e-04	171	51	3	43d8fd9b9546e84a652564fe96b514b34b06262b
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZHX3 HLA-DRA B3GNT7	9.83e-04	171	51	3	04346d4eb726875e3537e215ea081a0318ca4ddd
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FOXM1 GALNT14 FA2H	9.83e-04	171	51	3	13126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA ATP13A2 BANK1	9.83e-04	171	51	3	a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 FARP1	9.99e-04	172	51	3	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 EZH2 SMC1B	9.99e-04	172	51	3	8d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell	facs-Lung-nan-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE B3GNT7 BANK1	9.99e-04	172	51	3	7af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCell	severe_influenza-B_memory\|World / disease group, cell group and cell class (v2)	FA2H HLA-DRA BANK1	9.99e-04	172	51	3	0ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE GALNT14 FARP1	9.99e-04	172	51	3	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK\|bone_marrow / Manually curated celltypes from each tissue	FOXM1 EZH2 SMC1B	1.02e-03	173	51	3	8a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCell	facs-Trachea-nan-24m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	1.02e-03	173	51	3	71c90c57225e452c73bf7bea46b454c472bf5f76
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	FA2H EZH2 BANK1	1.02e-03	173	51	3	67f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE PLA2R1 KCNH5	1.02e-03	173	51	3	8ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A PIK3C2B BANK1	1.03e-03	174	51	3	01eff218e71a04201189a0313aaf91437fffed95
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	1.03e-03	174	51	3	9f7b983459d47b12a1b64e17e29b85a6ff4dc258
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A PIK3C2B BANK1	1.03e-03	174	51	3	f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A PIK3C2B BANK1	1.03e-03	174	51	3	2f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	1.03e-03	174	51	3	ba909e8789a62968e90bc1c4ab614de738c130f7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE PLA2R1 KCNH5	1.03e-03	174	51	3	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LIG3 PIP4K2C MBNL3	1.05e-03	175	51	3	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 SAMD9L PIK3C2B	1.05e-03	175	51	3	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FOXM1 EZH2 SMC1B	1.05e-03	175	51	3	553e68e8b439a2293efb969e1e2aa017ceb80daf
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FOXM1 EZH2 SMC1B	1.05e-03	175	51	3	16d4e97271df1db9a0d167fc82a90d84d20dd1f2
ToppCell	Healthy_donor-Plasmablast\|World / disease group, cell group and cell class (v2)	FOXM1 GALNT14 FA2H	1.05e-03	175	51	3	5293e00fda63a291aa393bdf82ebd4b80265049f
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FOXM1 EZH2 SMC1B	1.05e-03	175	51	3	289d2aa7164bc02b1876b99f2fb67baa8e030c4e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	1.05e-03	175	51	3	5092c5159f697e20bf8aa450c414ffd997738d25
ToppCell	IIF-Lymphocyte-B-B_intermediate\|IIF / Disease, Lineage and Cell Type	FA2H HLA-DRA BANK1	1.05e-03	175	51	3	327f8ee3669c3fc5ba50abc3b4f3e068637fd8d8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B ZC3H12D BANK1	1.05e-03	175	51	3	82482f3fc716701bed46dc65c2044577aed15427
ToppCell	facs-Trachea-24m-Hematologic-lymphocytic-B_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3C2B ZC3H12D BANK1	1.07e-03	176	51	3	318dc722b95e269002fb01a0feb91c0c8539e150
ToppCell	wk_08-11-Hematologic_Lymphocytic-B-Large_pre-B\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HLA-DRA BANK1 SMC1B	1.07e-03	176	51	3	78417a5ac2e45e97e7b4c56c78c25879a1b58f97
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	MPP2 LIG3 THOP1 MBNL2 ARHGAP35 AQR	4.24e-06	195	50	6	5252_DN
Drug	7-heptacosene	EZH1 EZH2	1.42e-05	3	50	2	CID006430696
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A	ZHX3 UBE4B GLE1 MBNL1 MBNL3	4.17e-05	176	50	5	5612_DN
Drug	Cycloheximide [66-81-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A	FOXM1 GALNT14 UBE4B GLE1 ATP13A2	4.76e-05	181	50	5	6220_DN
Drug	Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	MCMBP FA2H ARHGAP35 EZH1 BANK1	6.62e-05	194	50	5	1814_DN
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	MBNL2 FA2H ARHGAP35 EZH1 VPS53	6.95e-05	196	50	5	5261_DN
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	MPP2 POU1F1 ARHGAP35 CFAP69 MBNL3	6.95e-05	196	50	5	7167_UP
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; HL60; HT_HG-U133A	GLE1 FARP1 MBNL1 ATP13A2 BANK1	6.95e-05	196	50	5	3016_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZHX3 LIG3 UBE4B EZH1 ATP13A2	7.12e-05	197	50	5	3566_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA	MPP2 ZHX3 FA2H ARHGAP35 VPS53	7.12e-05	197	50	5	1013_UP
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A	GALNT14 MBNL2 FARP1 EZH1 VPS53	7.12e-05	197	50	5	4966_DN
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A	MCMBP MBNL2 ARHGAP35 CFAP69 VPS53	7.29e-05	198	50	5	3754_DN
Drug	Nicergoline; Up 200; 8.2uM; MCF7; HT_HG-U133A	MBNL2 FARP1 EZH1 CFAP69 VPS53	7.29e-05	198	50	5	6251_UP
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A	MPP2 RIN2 ARHGAP35 CFAP69 MBNL3	7.29e-05	198	50	5	6104_DN
Drug	Pregnenolone [145-13-1]; Up 200; 12.6uM; HL60; HT_HG-U133A	LIG3 MBNL2 PIP4K2C ATP13A2 MBNL3	7.47e-05	199	50	5	2497_UP
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A	MBNL2 POU1F1 EZH1 CFAP69 BANK1	7.47e-05	199	50	5	2109_UP
Drug	Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A	MPP2 ZHX3 MBNL2 FARP1 CFAP69	7.47e-05	199	50	5	6212_UP
Drug	haloperidol; Up 200; 10uM; HL60; HT_HG-U133A	GALNT14 LIG3 KDM5B MBNL2 ARHGAP35	7.65e-05	200	50	5	2704_UP
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; PC3; HT_HG-U133A	GALNT14 LIG3 FA2H KHNYN CFAP69	7.65e-05	200	50	5	5043_DN
Drug	VDM11	FOXM1 FA2H	9.86e-05	7	50	2	CID009887748
Disease	myotonic disease (implicated_via_orthology)	MBNL2 MBNL1 MBNL3	4.04e-09	3	48	3	DOID:450 (implicated_via_orthology)
Disease	myotonic dystrophy type 2 (implicated_via_orthology)	MBNL2 MBNL1 MBNL3	4.03e-08	5	48	3	DOID:0050759 (implicated_via_orthology)
Disease	myotonic dystrophy type 1 (implicated_via_orthology)	MBNL2 MBNL1 MBNL3	8.05e-08	6	48	3	DOID:11722 (implicated_via_orthology)
Disease	autoimmune thyroiditis (is_implicated_in)	HLA-DRA BANK1	1.69e-04	12	48	2	DOID:7188 (is_implicated_in)
Disease	Neurodegeneration with brain iron accumulation	FA2H ATP13A2	2.00e-04	13	48	2	cv:C2931845
Disease	health study participation	MPP2 OLA1 BIRC6 BANK1	2.87e-04	195	48	4	EFO_0010130
Disease	sensory peripheral neuropathy, remission	FOXM1 MPP2	6.41e-04	23	48	2	EFO_0009785, MONDO_0002321
Disease	upper aerodigestive tract neoplasm	FOXM1 FA2H HLA-DRA BIRC6	6.88e-04	246	48	4	EFO_0004284
Disease	pallidum volume	MPP2 BIRC6	7.59e-04	25	48	2	EFO_0006933
Disease	testosterone measurement	FOXM1 ZHX3 THOP1 MYO5A RIN2 MBNL1 BIRC6 BANK1	9.61e-04	1275	48	8	EFO_0004908
Disease	cognition	FOXM1 MPP2	1.58e-03	36	48	2	EFO_0003925
Disease	free androgen index	ZHX3 THOP1 UBE4B MBNL1	3.18e-03	374	48	4	EFO_0007005

Protein segments in the cluster

Peptide	Gene	Start	Entry
HARKAFPCFDEPIYK	TRHDE	271	Q9UKU6
KYTHFKELPTLLHCA	BANK1	336	Q8NDB2
NPSPCFKEVIHKHFY	BIRC6	4746	Q9NR09
LAHLHKKCPYSVPFY	GLE1	521	Q53GS7
PDHFPFFFKHILKAA	AQR	116	O60306
FDFLCQYHKPASKIP	OLA1	71	Q9NTK5
HHPPISAFYAECFNK	OSBPL9	501	Q96SU4
YCVVSGEKHFLFHPP	JMJD7	186	P0C870
LICFKDIKPAATHHY	HINT3	71	Q9NQE9
HLFLPDCHPSKYSLF	KIAA1109	591	Q2LD37
KTPPHIILHYCAFKT	KCNH5	201	Q8NCM2
KLPSCFKEHLIPHSY	FSIP2	4091	Q5CZC0
KYDCFLHPFHATPNT	EZH2	291	Q15910
LSHPFCYHPEVIKYT	OR51T1	176	Q8NGJ9
LHHVKELCSCPPYKY	KDM5B	716	Q9UGL1
PHLPRQVFVKCHFDY	MPP2	246	Q14168
HKVAHFKDYIPQAFP	LIG3	536	P49916
FLCRHEKIFHPNKGY	PIK3C2B	1371	O00750
VGHVFRKKHPYVFPD	GALNT14	331	Q96FL9
DYCFHTLTPEKPHLK	FA2H	356	Q7L5A8
ILHPRPINFKFYKHS	ATP13A2	411	Q9NQ11
KSLIFPNFEPLHKFH	FARP1	581	Q9Y4F1
EDHLFRKFHYLPFLP	HLA-DRA	166	P01903
REKCKYFHPPAHLQA	MBNL1	231	Q9NR56
YFHPPAHLQAKIKAA	MBNL1	236	Q9NR56
CKYFHPPAHLQAKIK	MBNL2	231	Q5VZF2
REKCKYFHPPAHLQA	MBNL3	226	Q9NUK0
IEDHFPYFKHIAKPG	FOXM1	266	Q08050
EIHYPPKLHCIFLGA	KHNYN	81	O15037
LKKFTPHHLVYCDFP	DCAF8L1	376	A6NGE4
HFLKWLDIYCPHVPF	B3GNT7	221	Q8NFL0
KCIVDFYHAEPPKKH	CFAP69	161	A5D8W1
PLHYLKPNSFVKFRC	MCMBP	56	Q9BTE3
RENLPSHFKFKEYCP	PIP4K2C	91	Q8TBX8
FEKKCNPAFLKFHPY	SPATA48	56	A4D263
PCLYKFPDHTLSHGF	POU1F1	76	P28069
PIFAKIINLYHHPGC	SAMD9L	731	Q8IVG5
KHIHFVYHPTKETCP	ARHGAP35	546	Q9NRY4
IRKPDTDYFKPHHCV	PLA2R1	1341	Q13018
TDYFKPHHCVALRIP	PLA2R1	1346	Q13018
YTFAFPPHHDTIKKE	SARDH	546	Q9UL12
HFPYAAHKCPFAFQK	ZFAND2A	36	Q8N6M9
PHIFHFVYKRIKNDP	RIN2	866	Q8WYP3
PFVQCKAKFHAPSFH	TRAPPC11	586	Q7Z392
FGRLFDLCHPIHKKY	SMC1B	516	Q8NDV3
PPHSKCFEDHLEQKY	SPATA31D1	486	Q6ZQQ2
PKFPTECFFLTLHAH	UBE4B	751	O95155
DCFLHPFHATPNVYK	EZH1	306	Q92800
VHSIKCVPLYHPYQK	GTF3C4	371	Q9UKN8
PFHGIVSKCFEPHLY	VPS53	416	Q5VIR6
ECPKVFKYLCHLLAH	ZSCAN4	316	Q8NAM6
KCKFYHPERPHHAQL	ZC3H12D	271	A2A288
YPHYFPLLKKCHVPE	THOP1	221	P52888
NSFHKFPYPTKAELC	ZHX3	321	Q9H4I2
HYVRCIKPNDFKFPF	MYO5A	656	Q9Y4I1