Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB46 HIC1 ZNF219 HDAC5 NFATC2 NFATC4 ZNF746 YLPM1	1.15e-04	320	92	8	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZBTB46 HIC1 ZNF219 HDAC5 NFATC2 NFATC4 ZNF746 YLPM1	1.31e-04	326	92	8	GO:0001217
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CDK9 CDX1 ZNF219 HDAC5 ZFHX4 SPIB NFATC2 NFATC4 EGR4 ZNF746 SOX17 HIF3A KLF4 HNF4A IKZF4 ZIC3	1.65e-04	1244	92	16	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	CDK9 CDX1 ZNF219 HDAC5 ZFHX4 SPIB NFATC2 NFATC4 EGR4 ZNF746 SOX17 HIF3A KLF4 HNF4A IKZF4 ZIC3	2.11e-04	1271	92	16	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZBTB46 HIC1 CDX1 ZNF219 HDAC5 ZFHX4 SPIB NFATC2 NFATC4 EGR4 ZNF746 YLPM1 SOX17 HIF3A KLF4 HNF4A ZIC3	2.21e-04	1412	92	17	GO:0000981
GeneOntologyMolecularFunction	transcription coregulator binding	CDK9 HDAC5 CHD6 KLF4 HNF4A	4.76e-04	140	92	5	GO:0001221
GeneOntologyMolecularFunction	SH3 domain binding	SHANK1 EFS INPPL1 BCAR1 CBLB	5.24e-04	143	92	5	GO:0017124
GeneOntologyMolecularFunction	transcription factor binding	CDK9 HDAC5 NFATC2 NFATC4 TLE1 SOX17 CHD6 KLF4 HNF4A MED13 IKZF4	6.80e-04	753	92	11	GO:0008134
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	CDK9 CDX1 ZNF219 HDAC5 ZFHX4 SPIB NFATC2 NFATC4 EGR4 ZNF746 SOX17 HIF3A KLF4 HNF4A IKZF4 ZIC3	9.59e-04	1459	92	16	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	CDX1 SPIB NFATC2 EGR4 SOX17 KLF4 HNF4A ZIC3 MEN1	1.19e-03	566	92	9	GO:0001216
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	CDK9 KMT2C CDX1 ZNF219 HDAC5 SPIB NFATC2 NFATC4 EGR4 ZNF746 SOX17 CHD6 HIF3A KLF4 HNF4A MED13 IKZF4 ZIC3 MEN1	9.87e-06	1390	92	19	GO:0045944
Domain	Med13_N	MED13L MED13	2.35e-05	2	91	2	PF11597
Domain	Mediator_Med13_N_met/fun	MED13L MED13	2.35e-05	2	91	2	IPR021643
Domain	Mediator_Med13	MED13L MED13	2.35e-05	2	91	2	IPR009401
Domain	Med13_C	MED13L MED13	2.35e-05	2	91	2	PF06333
Domain	ZINC_FINGER_C2H2_1	ZC3H7A ZBTB46 HIC1 TRIT1 ZNF219 ZFHX4 EGR4 ZNF746 ZC3H7B KLF4 ZNF598 IKZF4 ZIC3	9.68e-05	777	91	13	PS00028
Domain	Znf_C2H2	ZC3H7A ZBTB46 HIC1 TRIT1 ZNF219 ZFHX4 EGR4 ZNF746 ZC3H7B KLF4 ZNF598 IKZF4 ZIC3	1.38e-04	805	91	13	IPR007087
Domain	DUF3513	EFS BCAR1	1.40e-04	4	91	2	PF12026
Domain	CAS_DUF3513	EFS BCAR1	1.40e-04	4	91	2	IPR021901
Domain	NFAT	NFATC2 NFATC4	2.33e-04	5	91	2	IPR008366
Domain	ZINC_FINGER_C2H2_2	ZC3H7A ZBTB46 HIC1 ZNF219 ZFHX4 EGR4 ZNF746 ZC3H7B KLF4 ZNF598 IKZF4 ZIC3	3.72e-04	775	91	12	PS50157
Domain	Znf_C2H2-like	ZC3H7A ZBTB46 HIC1 ZNF219 ZFHX4 EGR4 ZNF746 ZC3H7B KLF4 ZNF598 IKZF4 ZIC3	4.73e-04	796	91	12	IPR015880
Domain	ZnF_C2H2	ZC3H7A ZBTB46 HIC1 ZNF219 ZFHX4 EGR4 ZNF746 ZC3H7B KLF4 ZNF598 IKZF4 ZIC3	5.41e-04	808	91	12	SM00355
Domain	RHD_dimer	NFATC2 NFATC4	1.03e-03	10	91	2	IPR032397
Domain	RHD_dimer	NFATC2 NFATC4	1.03e-03	10	91	2	PF16179
Domain	NFkB/Dor	NFATC2 NFATC4	1.03e-03	10	91	2	IPR000451
Domain	REL_1	NFATC2 NFATC4	1.03e-03	10	91	2	PS01204
Domain	RHD_DNA_bind_dom	NFATC2 NFATC4	1.03e-03	10	91	2	IPR011539
Domain	RHD_DNA_bind	NFATC2 NFATC4	1.03e-03	10	91	2	PF00554
Domain	REL_2	NFATC2 NFATC4	1.03e-03	10	91	2	PS50254
Domain	-	NFATC2 NFATC4	1.03e-03	10	91	2	2.60.40.340
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CDK9 HDAC5 NFATC2 NFATC4	1.26e-05	32	64	4	M39521
Pathway	WP_MESODERMAL_COMMITMENT_PATHWAY	AMH ZFHX4 SOX17 KLF4 HNF4A ZIC3	6.61e-05	153	64	6	M39546
Pathway	WP_GDNFRET_SIGNALING_AXIS	SOX17 ROBO2 RET	1.29e-04	22	64	3	MM15887
Pathway	WP_GDNFRET_SIGNALING_AXIS	SOX17 ROBO2 RET	1.48e-04	23	64	3	M39814
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	KIAA1671 PRUNE2 AATK HDAC5 NFATC4 INPPL1 YLPM1 CCDC87 RET BCAR1	2.20e-07	430	92	10	35044719
Pubmed	Interaction network of human early embryonic transcription factors.	KIAA1671 KMT2C HDAC5 ZFHX4 WDR6 TLE1 ZNF746 FBRS MIDEAS	4.08e-07	351	92	9	38297188
Pubmed	Human transcription factor protein interaction networks.	KIAA1671 KMT2C HDAC5 ZFHX4 NFATC4 TLE1 ZNF746 YLPM1 FBRS SOX17 CHD6 KLF4 HNF4A MIDEAS ZIC3 SORD	1.00e-06	1429	92	16	35140242
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDK9 SCAF1 KMT2C NDOR1 AATK SZT2 VWA8 INPPL1 CASKIN1 FBRS MED13L ZC3H7B KLF4 MED13	1.24e-06	1105	92	14	35748872
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RALGAPA1 ZC3H7A NEO1 MTMR4 NFATC4 WDR6 TLE1 YLPM1 KIRREL1 TTC17 CHD6	3.87e-06	733	92	11	34672954
Pubmed	SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading.	INPPL1 BCAR1	6.92e-06	2	92	2	11158326
Pubmed	Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.	RET CBLB	6.92e-06	2	92	2	16525057
Pubmed	Role of transcription factor NFAT in glucose and insulin homeostasis.	NFATC2 NFATC4	6.92e-06	2	92	2	16908540
Pubmed	Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse.	MED13L MED13	6.92e-06	2	92	2	29325037
Pubmed	The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.	NDOR1 COL17A1	6.92e-06	2	92	2	31435021
Pubmed	Deletion of the Mitochondrial Protein VWA8 Induces Oxidative Stress and an HNF4α Compensatory Response in Hepatocytes.	VWA8 HNF4A	6.92e-06	2	92	2	31702900
Pubmed	Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban.	COL17A1 ITGA2B	6.92e-06	2	92	2	16487966
Pubmed	Menin regulates the function of hematopoietic stem cells and lymphoid progenitors.	NDOR1 MEN1	6.92e-06	2	92	2	19228930
Pubmed	Ferroptosis is governed by differential regulation of transcription in liver cancer.	HIC1 HNF4A	6.92e-06	2	92	2	31108460
Pubmed	Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family.	RET MEN1	6.92e-06	2	92	2	21678021
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TLE1 YLPM1 FBRS MED13L KLF4 MIDEAS MED13	7.48e-06	268	92	7	33640491
Pubmed	Dual lineage-specific expression of Sox17 during mouse embryogenesis.	SOX17 ITGA2B HNF4A	9.78e-06	16	92	3	22865702
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HIC1 CDX1 SPIB NFATC2 NFATC4 EGR4 KLF4 HNF4A ZIC3	1.44e-05	544	92	9	28473536
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KMT2C HIC1 ZNF219 NFATC2 NFATC4 ZNF746 HIF3A KLF4 HNF4A IKZF4	1.87e-05	709	92	10	22988430
Pubmed	Primary hyperparathyroidism--what the nephrologist should know--an update.	RET MEN1	2.07e-05	3	92	2	17138574
Pubmed	Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs.	EFS BCAR1	2.07e-05	3	92	2	9038154
Pubmed	Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons.	NDOR1 RET	2.07e-05	3	92	2	30018091
Pubmed	Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.	EFS BCAR1	2.07e-05	3	92	2	7479864
Pubmed	Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase.	RET BCAR1	2.07e-05	3	92	2	10208419
Pubmed	The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.	NDOR1 MEN1	2.07e-05	3	92	2	16415155
Pubmed	Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids.	HDAC5 KLF4	2.07e-05	3	92	2	18768922
Pubmed	High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy.	CACNA1A HNF4A	2.07e-05	3	92	2	37342032
Pubmed	The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac.	NDOR1 HNF4A	2.07e-05	3	92	2	34001900
Pubmed	Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.	RET MEN1	2.07e-05	3	92	2	28674121
Pubmed	Biallelic variants in genes previously associated with dominant inheritance: CACNA1A, RET and SLC20A2.	CACNA1A RET	2.07e-05	3	92	2	34267336
Pubmed	BP180 dysfunction triggers spontaneous skin inflammation in mice.	NDOR1 COL17A1	2.07e-05	3	92	2	29866844
Pubmed	Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes.	RET BCAR1	2.07e-05	3	92	2	35031902
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SPTBN4 COL17A1 VWA8 SSPOP MED13	2.56e-05	130	92	5	12421765
Pubmed	Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.	NEO1 SOX17 KLF4	2.66e-05	22	92	3	37823339
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 KMT2C AATK HDAC5 CHD6 MED13L	3.08e-05	225	92	6	12168954
Pubmed	Nuclear factor of activated T cells is activated in the endothelium of retinal microvessels in diabetic mice.	NFATC2 NFATC4	4.14e-05	4	92	2	25918731
Pubmed	Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT.	NFATC2 NFATC4	4.14e-05	4	92	2	9660947
Pubmed	NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis.	NFATC2 NFATC4	4.14e-05	4	92	2	26527057
Pubmed	Functional dissection of the alpha-synuclein promoter: transcriptional regulation by ZSCAN21 and ZNF219.	ZNF219 HNF4A	4.14e-05	4	92	2	19549071
Pubmed	HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.	NFATC2 NFATC4	4.14e-05	4	92	2	16260021
Pubmed	Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model.	EFS BCAR1	4.14e-05	4	92	2	9748319
Pubmed	FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment.	MED13L MED13	4.14e-05	4	92	2	29809150
Pubmed	Ret Signaling Is Required for Tooth Pulp Innervation during Organogenesis.	NDOR1 RET	4.14e-05	4	92	2	30958726
Pubmed	Alternative splicing and expression of human and mouse NFAT genes.	NFATC2 NFATC4	4.14e-05	4	92	2	18675896
Pubmed	Transcription factors of the NFAT family: regulation and function.	NFATC2 NFATC4	4.14e-05	4	92	2	9143705
Pubmed	Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration.	HIC1 NDOR1	4.14e-05	4	92	2	31809738
Pubmed	Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.	HIC1 NDOR1	4.14e-05	4	92	2	31978365
Pubmed	Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.	NFATC2 NFATC4	4.14e-05	4	92	2	23962643
Pubmed	Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.	KMT2C MEN1	4.14e-05	4	92	2	19703992
Pubmed	Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.	NEO1 IGDCC4	4.14e-05	4	92	2	10708514
Pubmed	The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis.	NFATC2 NFATC4	4.14e-05	4	92	2	24970700
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	KMT2C ZNF219 MIDEAS ZIC3 MEN1	4.46e-05	146	92	5	23892456
Pubmed	Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.	NFATC2 NFATC4	6.89e-05	5	92	2	17693409
Pubmed	Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.	NFATC2 NFATC4	6.89e-05	5	92	2	22593154
Pubmed	Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.	NFATC2 EGR4	6.89e-05	5	92	2	12560487
Pubmed	Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif.	NFATC2 NFATC4	6.89e-05	5	92	2	7999066
Pubmed	Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT.	NFATC2 NFATC4	6.89e-05	5	92	2	10089876
Pubmed	Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis.	SOX17 HNF4A	6.89e-05	5	92	2	19913509
Pubmed	Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification.	SOX17 ITGA2B	6.89e-05	5	92	2	20228271
Pubmed	Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder.	SOX17 HNF4A	6.89e-05	5	92	2	29023691
Pubmed	IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus.	ZBTB46 NDOR1	6.89e-05	5	92	2	31434685
Pubmed	NFAT: ubiquitous regulator of cell differentiation and adaptation.	NFATC2 NFATC4	6.89e-05	5	92	2	11877454
Pubmed	Integration of calcium and cyclic AMP signaling pathways by 14-3-3.	NFATC2 NFATC4	6.89e-05	5	92	2	10611249
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 KMT2C SZT2 VWA8 CASKIN1 ROBO2 ZC3H7B MED13	8.26e-05	529	92	8	14621295
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	KMT2C ZNF219 MED13L MIDEAS MED13	8.44e-05	167	92	5	20362541
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK9 KIAA1671 RALGAPA1 MTMR4 DSC2 PIK3C3 INPPL1 OTUD7A BCAR1 ZNF598	9.49e-05	861	92	10	36931259
Pubmed	A SOX17-PDGFB signaling axis regulates aortic root development.	COL15A1 SOX17 KLF4	1.01e-04	34	92	3	35831318
Pubmed	A multipotent progenitor domain guides pancreatic organogenesis.	ZNF219 SOX17 HIF3A HNF4A	1.03e-04	91	92	4	17609113
Pubmed	Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.	NFATC2 NFATC4	1.03e-04	6	92	2	24352425
Pubmed	A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.	NFATC2 NFATC4	1.03e-04	6	92	2	16141075
Pubmed	ROBO2-mediated RALDH2 signaling is required for common nephric duct fusion with primitive bladder.	ROBO2 RET	1.03e-04	6	92	2	32562756
Pubmed	Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.	NFATC2 NFATC4	1.03e-04	6	92	2	12788643
Pubmed	Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux.	ROBO2 RET	1.03e-04	6	92	2	19959718
Pubmed	Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.	SOX17 MEN1	1.03e-04	6	92	2	25866973
Pubmed	Notch2-dependent DC2s mediate splenic germinal center responses.	ZBTB46 KLF4	1.03e-04	6	92	2	30279176
Pubmed	SHIP2 (SH2 domain-containing inositol phosphatase 2) SH2 domain negatively controls SHIP2 monoubiquitination in response to epidermal growth factor.	INPPL1 CBLB	1.03e-04	6	92	2	19880507
Pubmed	Expression Profiling and Functional Analysis of Candidate Col10a1 Regulators Identified by the TRAP Program.	SOX17 KLF4	1.03e-04	6	92	2	34276786
Pubmed	Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering.	NFATC2 NFATC4	1.03e-04	6	92	2	8814265
Pubmed	The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins.	NFATC2 NFATC4	1.03e-04	6	92	2	25728138
Pubmed	Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.	SOX17 HNF4A	1.03e-04	6	92	2	29635272
Pubmed	Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus.	SPIB HNF4A	1.03e-04	6	92	2	37399024
Pubmed	Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells.	NFATC2 NFATC4	1.03e-04	6	92	2	16690925
Pubmed	Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.	CDK9 IKZF4	1.03e-04	6	92	2	23732910
Pubmed	The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.	PIK3C3 HNF4A	1.03e-04	6	92	2	21283715
Pubmed	Axon guidance genes control hepatic artery development.	NEO1 ROBO2 HNF4A	1.20e-04	36	92	3	37497580
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KIAA1671 HDAC5 ZFHX4 WDR6 TLE1 FBRS CHD6	1.25e-04	418	92	7	34709266
Pubmed	NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.	NFATC2 NFATC4	1.44e-04	7	92	2	16554754
Pubmed	Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.	NDOR1 MEN1	1.44e-04	7	92	2	36098964
Pubmed	T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node.	ZBTB46 NDOR1	1.44e-04	7	92	2	28801233
Pubmed	Role of fibroblast growth factor receptor 2 in kidney mesenchyme.	ROBO2 RET	1.44e-04	7	92	2	18670373
Pubmed	Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.	NFATC2 NFATC4	1.44e-04	7	92	2	17430895
Pubmed	The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development.	MED13L MED13	1.44e-04	7	92	2	12093747
Pubmed	Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells.	NFATC2 NFATC4	1.44e-04	7	92	2	18097055
Pubmed	NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.	NFATC2 NFATC4	1.44e-04	7	92	2	18218901
Pubmed	A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells.	NFATC2 KLF4	1.44e-04	7	92	2	8940147
Pubmed	SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation.	CDK9 MEN1	1.44e-04	7	92	2	19818711
Pubmed	Calcium/NFAT signalling promotes early nephrogenesis.	NFATC2 NFATC4	1.44e-04	7	92	2	21295565
Pubmed	A census of human transcription factors: function, expression and evolution.	HIC1 CDX1 ZFHX4 NFATC2 NFATC4 SOX17 HIF3A KLF4 HNF4A MIDEAS	1.46e-04	908	92	10	19274049
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	WDR6 INPPL1 KIRREL1 CBLB	1.66e-04	103	92	4	21706016
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CDK9 KIAA1671 SCAF1 ZNF219 DSC2 ZFHX4 VWA8 WDR6 RSF1 FBRS SEZ6L	1.77e-04	1116	92	11	31753913
Interaction	PAX7 interactions	KMT2C ZFHX4 TLE1 ZNF746 FBRS CHD6 MIDEAS	1.49e-06	124	91	7	int:PAX7
Interaction	NFIB interactions	KMT2C TLE1 FBRS SOX17 HNF4A MIDEAS MEN1	3.67e-06	142	91	7	int:NFIB
Interaction	KDM6A interactions	KMT2C TLE1 PLEKHA4 SOX17 KLF4 HNF4A MEN1	8.75e-06	162	91	7	int:KDM6A
Interaction	EGR2 interactions	KMT2C HDAC5 ZFHX4 TLE1 ZNF746 FBRS MIDEAS	1.25e-05	171	91	7	int:EGR2
Interaction	TBXT interactions	KMT2C ZFHX4 TLE1 ZNF746 FBRS MIDEAS	1.43e-05	116	91	6	int:TBXT
Interaction	MED24 interactions	PLEKHA4 BCAR1 MED13L HNF4A MED13 MEN1	2.50e-05	128	91	6	int:MED24
Interaction	PAX9 interactions	KMT2C ZFHX4 TLE1 FBRS KLF4 MIDEAS	2.73e-05	130	91	6	int:PAX9
Interaction	NUP93 interactions	AATK HDAC5 ARMC5 RSF1 PLEKHA4 SOX17 ZNF598 MEN1	2.96e-05	269	91	8	int:NUP93
Interaction	ZNF281 interactions	ZNF746 PLEKHA4 SOX17 BCAR1 KLF4 HNF4A MEN1	3.10e-05	197	91	7	int:ZNF281
Interaction	GATA2 interactions	KMT2C HDAC5 ZFHX4 TLE1 FBRS CHD6 MIDEAS	3.31e-05	199	91	7	int:GATA2
Interaction	FEV interactions	KMT2C ZFHX4 TLE1 ZNF746 FBRS CHD6 MIDEAS	3.76e-05	203	91	7	int:FEV
Interaction	IRF4 interactions	KMT2C SPIB NFATC2 TLE1 FBRS	4.15e-05	85	91	5	int:IRF4
Interaction	GSC interactions	KMT2C ZFHX4 TLE1 FBRS MIDEAS	4.64e-05	87	91	5	int:GSC
Interaction	ZNF148 interactions	NDOR1 NFATC2 INPPL1 PLEKHA4 HNF4A MEN1	4.85e-05	144	91	6	int:ZNF148
Interaction	SOX17 interactions	KMT2C TLE1 FBRS SOX17 MIDEAS	7.07e-05	95	91	5	int:SOX17
Interaction	CNOT9 interactions	CDK9 KIAA1671 ZC3H7A AATK PLEKHA4 TTC17 ZNF598	8.49e-05	231	91	7	int:CNOT9
Interaction	NUP35 interactions	CDK9 KMT2C TLE1 YLPM1 FBRS PLEKHA4 BCAR1 MIDEAS SORD	1.27e-04	424	91	9	int:NUP35
Cytoband	17q22-q23	MTMR4 MED13	5.93e-05	6	92	2	17q22-q23
Cytoband	19q13.3-q13.4	SCAF1 SPIB	3.05e-04	13	92	2	19q13.3-q13.4
Cytoband	7q36.1	KMT2C ZNF746 SSPOP	4.55e-04	74	92	3	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SHANK1 SPTBN4 SCAF1 LILRB3 SPIB GPATCH1 PLEKHA4 HIF3A ATP4A	6.58e-04	1192	92	9	chr19q13
GeneFamily	Cas scaffolding proteins	EFS BCAR1	9.08e-05	4	71	2	469
GeneFamily	Nuclear factors of activated T-cells	NFATC2 NFATC4	1.51e-04	5	71	2	665
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB46 HIC1 ZNF219 EGR4 ZNF746 KLF4 ZNF598 IKZF4 ZIC3	1.92e-03	718	71	9	28
GeneFamily	Cadherin related	DCHS1 RET	1.99e-03	17	71	2	24
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NEO1 KIRREL1 ROBO2 IGDCC4	3.70e-03	161	71	4	593
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 VWA8 NFATC4 LOXL1 PLEKHA4 SLC19A2 DCHS1 HIF3A KLF4 IGDCC4	3.39e-07	607	92	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#2	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 VWA8 NFATC4 LOXL1 PLEKHA4 SLC19A2 DCHS1 HIF3A KLF4 IGDCC4	8.42e-07	655	92	14	Facebase_RNAseq_e9.5_Olfactory Placode_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 SLC19A2 DCHS1 PLPPR3 HIF3A KLF4 IGDCC4	3.05e-06	731	92	14	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 SLC19A2 DCHS1 HIF3A KLF4 IGDCC4	4.61e-06	652	92	13	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1	ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 SLC19A2 DCHS1 HIF3A KLF4 IGDCC4	8.92e-06	589	92	12	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	9.23e-06	591	92	12	Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#2	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	1.00e-05	596	92	12	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#2	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	2.10e-05	642	92	12	Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#3	ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	3.40e-05	567	92	11	Facebase_RNAseq_e10.5_Olfactory Pit_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 YLPM1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	6.12e-05	834	92	13	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	6.91e-05	726	92	12	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	7.67e-05	734	92	12	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	SPTBN4 ZC3H7A COL15A1 COL17A1 ZFHX4 NFATC4 LOXL1 PLEKHA4 DCHS1 HIF3A KLF4 IGDCC4	8.72e-05	744	92	12	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	HIC1 NEO1 ZFHX4 EFS YLPM1 HIF3A ZC3H7B KLF4 MAP10 SLC4A3 IKZF4 IGDCC4	1.55e-04	791	92	12	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2	SHANK1 CACNA1A HDAC5 SZT2 NFATC4 GPATCH1 ARMC5 SLC19A2 ROBO2 PLPPR3 ITGA2B CBLB SLC4A3 IKZF4 IGDCC4	2.04e-04	1208	92	15	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ZNF219 AATK COL15A1 FIGNL2 PLEKHA4 ZC3H7B PCBP4 MED13	4.66e-09	184	92	8	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	COVID-19_Convalescent-cDC\|COVID-19_Convalescent / Disease condition and Cell class	COL15A1 COL17A1 SPIB NFATC2 FIGNL2 PLEKHA4 SEZ6L	6.76e-08	171	92	7	9ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCell	COVID-19_Convalescent-cDC-\|COVID-19_Convalescent / Disease condition and Cell class	COL15A1 COL17A1 SPIB NFATC2 FIGNL2 PLEKHA4 SEZ6L	6.76e-08	171	92	7	fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KIAA1671 HIC1 COL15A1 SOX17 DCHS1 BCAR1	3.51e-06	198	92	6	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KIAA1671 HIC1 COL15A1 SOX17 DCHS1 BCAR1	3.51e-06	198	92	6	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LILRB3 COL17A1 CCDC87 SSPOP	1.14e-05	67	92	4	820120f1f8500c948ef54280e5237f9b311f1b3e
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LILRB3 COL17A1 CCDC87 SSPOP	1.14e-05	67	92	4	c6a3ac0829f924e0c7822df2ef8f45e7925f2d3d
ToppCell	metastatic_Brain-Myeloid_cells-CD1c+_DCs\|metastatic_Brain / Location, Cell class and cell subclass	HIC1 CDX1 NDOR1 SPIB SEZ6L	1.99e-05	159	92	5	35a63ca521635389a1edc7c81157793b8ad24d38
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D231\|Adult / Lineage, Cell type, age group and donor	SPTBN4 LOXL1 DCHS1 ROBO2 PCBP4	2.30e-05	164	92	5	3d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	EGR4 TLE1 CLIC3 CCDC87 CBLB	2.44e-05	166	92	5	ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1A KMT2C CLIC3 PLEKHA4 KIRREL1	2.59e-05	168	92	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A ZBTB46 CLIC3 DCHS1 SSPOP	3.06e-05	174	92	5	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	LOXL1 PLEKHA4 ROBO2 PCBP4 SLC4A3	3.23e-05	176	92	5	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	LOXL1 PLEKHA4 ROBO2 PCBP4 SLC4A3	3.23e-05	176	92	5	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HIC1 MTMR4 COL15A1 PLEKHA4 KIRREL1	3.41e-05	178	92	5	cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 WDR6 CASKIN1 SLC4A3 ATP4A	3.60e-05	180	92	5	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIAA1671 CDX1 DSC2 ZNF598 HNF4A	3.60e-05	180	92	5	8d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 WDR6 CASKIN1 SLC4A3 ATP4A	3.60e-05	180	92	5	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HIC1 COL15A1 DCHS1 BCAR1 HNF4A	3.79e-05	182	92	5	997d37ca2af661c92a56add888762724dfccc890
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic-DC2\|bone_marrow / Manually curated celltypes from each tissue	ZBTB46 SPIB KLF4 SLC4A3 SEZ6L	3.89e-05	183	92	5	f482e4fe011fa450a475034b1e25587233855bdb
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A EGR4 PLEKHA4 HIF3A RET	3.89e-05	183	92	5	49f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SHANK1 COL15A1 EFS KIRREL1 IGDCC4	4.10e-05	185	92	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZBTB46 HIC1 COL15A1 SOX17 RET	4.21e-05	186	92	5	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	HIC1 SPIB KLF4 SLC4A3 SEZ6L	4.31e-05	187	92	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 KMT2C MED13L CBLB MED13	4.42e-05	188	92	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A PRUNE2 OTUD7A RET PCBP4	4.42e-05	188	92	5	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZBTB46 SPIB KLF4 SLC4A3 SEZ6L	4.54e-05	189	92	5	c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZBTB46 SPIB KLF4 SLC4A3 SEZ6L	4.54e-05	189	92	5	807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	ZBTB46 HIC1 CDX1 SPIB SLC4A3	4.65e-05	190	92	5	468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ZFHX4 PLEKHA4 ROBO2 IGDCC4	4.65e-05	190	92	5	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZNF219 EFS ROBO2 PCBP4 SEZ6L	4.77e-05	191	92	5	48cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDOR1 COL17A1 CLIC3 CHIT1 KLF4	4.77e-05	191	92	5	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZNF219 EFS ROBO2 PCBP4 SEZ6L	4.77e-05	191	92	5	e4c1c533771b582e21683dbec6f93a558d865e00
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK1 ZBTB46 NEO1 TLE1 KLF4	4.89e-05	192	92	5	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL15A1 EFS LOXL1 KIRREL1 IGDCC4	5.14e-05	194	92	5	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	facs-Thymus-Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 MGAT3 COL17A1 SOX17 KLF4	5.14e-05	194	92	5	255d6eead8da740a942a5e7d554dbd895d736d1a
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 ROBO2 RET BCAR1 SEZ6L	5.26e-05	195	92	5	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	facs-Thymus-Epithelium-24m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 MGAT3 COL17A1 SOX17 KLF4	5.26e-05	195	92	5	cc89261bb091ef978bd73cffc68ccdd00a8786d1
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A KMT2C ROBO2 RET SEZ6L	5.26e-05	195	92	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A KMT2C ROBO2 RET SEZ6L	5.26e-05	195	92	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SHANK1 SPIB CLIC3 RET SLC4A3	5.39e-05	196	92	5	b10b386aacc672949560df2dbb0d4f76cf62e213
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CDX1 COL15A1 LOXL1 KIRREL1 ROBO2	5.52e-05	197	92	5	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-tip_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KIAA1671 HIC1 COL15A1 SOX17 BCAR1	5.52e-05	197	92	5	b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MGAT3 AATK COL15A1 EFS ZNF598	5.79e-05	199	92	5	a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MGAT3 AATK COL15A1 EFS ZNF598	5.79e-05	199	92	5	8dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HIC1 COL15A1 SOX17 DCHS1 BCAR1	5.93e-05	200	92	5	77ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HIC1 LOXL1 SLC19A2 KLF4 IGDCC4	5.93e-05	200	92	5	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HIC1 LOXL1 SLC19A2 KLF4 IGDCC4	5.93e-05	200	92	5	05486d86868f6a93429226063cca270f00dd8714
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HIC1 LOXL1 SLC19A2 KLF4 IGDCC4	5.93e-05	200	92	5	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HIC1 DSC2 SOX17 DCHS1 BCAR1	5.93e-05	200	92	5	ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell	5'-Adult-LargeIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDX1 COL17A1 DSC2 KLF4 HNF4A	5.93e-05	200	92	5	3f29823952a4303451997dd5177a51179bd20540
ToppCell	5'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDX1 COL17A1 DSC2 KLF4 HNF4A	5.93e-05	200	92	5	b2fa6e44ace5897766792ed97ffafc11555175e7
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFATC4 LOXL1 PLEKHA4 KIRREL1	1.53e-04	130	92	4	e5acaa9aaa22b10d11410e2c01647b31354c21ed
ToppCell	COVID-19_Convalescent-PLT_3\|World / Disease Group and Platelet Clusters	NFATC2 VWA8 GPATCH1 CHD6	1.87e-04	137	92	4	bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	SPTBN4 AATK ROBO2 SEZ6L	2.03e-04	140	92	4	82b150e9e9962460a5cd6bef7ee04f28f5c05d1a
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SHANK1 VWA8 CHIT1 ZC3H7B	2.14e-04	142	92	4	61eefa32926a057e53747633bf4a81f09ea721c5
ToppCell	COVID-19_Mild-PLT_3\|World / Disease Group and Platelet Clusters	HIC1 NEO1 VWA8 BCAR1	2.44e-04	147	92	4	9d3271aa735ddb6f32ab864d7afcfb0f8754383b
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM170B LOXL1 SEZ6L ZIC3	2.51e-04	148	92	4	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	SPTBN4 AATK ROBO2 SEZ6L	2.57e-04	149	92	4	649eb3441fa859591ea85f1ed5fcf08af272a32b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SHANK1 FIGNL2 KIRREL1 RET	2.57e-04	149	92	4	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	E17.5-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZFHX4 CLIC3 PLEKHA4 CHIT1	2.64e-04	150	92	4	201d5b68e71c6c003285428be96c488e6d526edf
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIC1 LOXL1 ROBO2 RET	2.71e-04	151	92	4	32d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK1 SOX17 HIF3A BEGAIN	2.92e-04	154	92	4	1899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 FBRS PLEKHA4 DCHS1	2.92e-04	154	92	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFATC2 IKZF4 SEZ6L BEGAIN	2.99e-04	155	92	4	d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 NFATC2 CBLB BEGAIN	2.99e-04	155	92	4	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRUNE2 NFATC4 HIF3A PCBP4	2.99e-04	155	92	4	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 NFATC2 CBLB BEGAIN	2.99e-04	155	92	4	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	PBMC-Mild-cDC_6\|Mild / Compartment, Disease Groups and Clusters	HIC1 AATK COL17A1 DCHS1	3.07e-04	156	92	4	3db686849844120b3e376599929d11ad06f0d577
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASSF5 ZNF219 PLEKHA4 ITGA2B	3.14e-04	157	92	4	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASSF5 ZNF219 PLEKHA4 ITGA2B	3.14e-04	157	92	4	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASSF5 ZNF219 PLEKHA4 ITGA2B	3.14e-04	157	92	4	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	HIC1 COL15A1 LOXL1 KIRREL1	3.29e-04	159	92	4	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL1 ROBO2 CBLB SSPOP	3.29e-04	159	92	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL1 ROBO2 CBLB SSPOP	3.29e-04	159	92	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL1 ROBO2 CBLB SSPOP	3.29e-04	159	92	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFS NFATC4 OTUD7A IGDCC4	3.37e-04	160	92	4	778faada072e3abfa76a9a06fd4885fb63de7902
ToppCell	Severe-Lymphoid-NK-\|Severe / Condition, Lineage, Cell class and cell subclass	NDOR1 TLE1 CLIC3 CBLB	3.37e-04	160	92	4	d276c6cb8317d5fb19e7b4fe5238abaf0272d4c6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB46 LOXL1 ROBO2 PCBP4	3.45e-04	161	92	4	580153e131247e6ec12a1a920f050a0a763e7e87
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ZFHX4 PLEKHA4 ITGA2B SSPOP	3.62e-04	163	92	4	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GPATCH1 FIGNL2 KIRREL1 HIF3A	3.70e-04	164	92	4	08c725548e751f815b4df778607270498204b353
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 CACNA1A RET SEZ6L	3.70e-04	164	92	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIAA1671 AATK EGR4 MED13L	3.79e-04	165	92	4	35a6de30438de364ccca948fc932da541a69ef89
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIC3 ROBO2 IGDCC4 BEGAIN	3.79e-04	165	92	4	4cdd80580d5638fd649280ba3893251c2f898f3f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIT1 GPATCH1 OTUD7A SEZ6L	3.79e-04	165	92	4	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIC3 ROBO2 IGDCC4 BEGAIN	3.79e-04	165	92	4	c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EFS NFATC4 HIF3A IGDCC4	3.88e-04	166	92	4	f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A PRUNE2 LILRB3 ZFHX4	3.97e-04	167	92	4	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 MGAT3 RET IKZF4	4.06e-04	168	92	4	04a7810f95196a21325356b42084f96c11af5964
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	HIC1 COL15A1 KIRREL1 IGDCC4	4.06e-04	168	92	4	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL15A1 LOXL1 PLEKHA4 RET	4.06e-04	168	92	4	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL15A1 LOXL1 PLEKHA4 RET	4.06e-04	168	92	4	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LILRB3 COL17A1 CCDC87	4.10e-04	70	92	3	ee86e3790ff1fd684b7dff8c9de70e75133e9046
ToppCell	COVID-19-Heart-Adipocyte\|Heart / Disease (COVID-19 only), tissue and cell type	PRUNE2 AMH ZFHX4 SLC19A2	4.15e-04	169	92	4	bd39f85b48207955f80ca120a11e15a0124117b9
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 CACNA1A RET SEZ6L	4.15e-04	169	92	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 ZBTB46 KLF4 IGDCC4	4.24e-04	170	92	4	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPIB CLIC3 RET SLC4A3	4.34e-04	171	92	4	4fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCell	ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, Lineage and Cell Type	SHANK1 SPIB CLIC3 SLC4A3	4.34e-04	171	92	4	72c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	CACNA1A MGAT3 SPIB TLE1	4.34e-04	171	92	4	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	CACNA1A PRUNE2 TLE1 KIRREL1	4.34e-04	171	92	4	e99ecae66530d1ae09330cee408c8f3950b87e67
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A	PRUNE2 HIC1 ZNF219 AATK ZFHX4 EFS EGR4 ZC3H7B	1.53e-06	200	92	8	3081_UP
Drug	iodoform	CDK9 TRIT1 CHIT1	3.52e-06	8	92	3	CID000006374
Drug	Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A	SHANK1 CACNA1A PRUNE2 ZFHX4 PLPPR3 ZC3H7B SEZ6L	1.39e-05	194	92	7	2311_UP
Drug	Hexestrol [84-16-2]; Up 200; 14.8uM; PC3; HT_HG-U133A	PRUNE2 NDOR1 DCHS1 ITGA2B HNF4A IKZF4 BEGAIN	1.54e-05	197	92	7	5776_UP
Drug	Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A	SHANK1 HDAC5 DSC2 ZFHX4 HIF3A ZC3H7B HNF4A	1.59e-05	198	92	7	2319_UP
Drug	Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; HL60; HT_HG-U133A	CDX1 COL17A1 ZFHX4 MED13L HNF4A IKZF4 BEGAIN	1.69e-05	200	92	7	2434_UP
Disease	Familial vesicoureteral reflux	SOX17 ROBO2	2.75e-05	3	90	2	cv:C4706552
Disease	Multiple Endocrine Neoplasia	RET MEN1	2.75e-05	3	90	2	C0027662
Disease	Vesicoureteral reflux	SOX17 ROBO2	2.75e-05	3	90	2	cv:C0042580
Disease	Familial vesicoureteral reflux	SOX17 ROBO2	2.75e-05	3	90	2	C4706552
Disease	exfoliation syndrome	CACNA1A LOXL1	5.50e-05	4	90	2	EFO_0004235
Disease	Vesico-Ureteral Reflux	SOX17 ROBO2	5.50e-05	4	90	2	C0042580
Disease	vesicoureteral reflux (is_implicated_in)	SOX17 ROBO2	9.15e-05	5	90	2	DOID:9620 (is_implicated_in)
Disease	Exfoliation Syndrome	CACNA1A LOXL1	1.37e-04	6	90	2	C0206368
Disease	familial hemiplegic migraine (implicated_via_orthology)	CACNA1A ATP4A	1.91e-04	7	90	2	DOID:0060178 (implicated_via_orthology)
Disease	pulse pressure measurement	SPTBN4 AMH ZBTB46 HIC1 COL15A1 ZFHX4 NFATC2 LOXL1 COASY BCAR1 ZCCHC2 MED13L SSPOP	3.02e-04	1392	90	13	EFO_0005763
Disease	Liver Diseases, Parasitic	KMT2C ROBO2	3.27e-04	9	90	2	C0023897
Disease	obesity (implicated_via_orthology)	ZFHX4 DCHS1 MED13L HNF4A MED13	5.21e-04	215	90	5	DOID:9970 (implicated_via_orthology)
Disease	Carcinoma, Neuroendocrine	RET MEN1	5.95e-04	12	90	2	C0206695
Disease	Carcinoma of Endocrine Gland	RET MEN1	9.41e-04	15	90	2	C1704374
Disease	Intrahepatic cholestasis of pregnancy	HNF4A ATP4A	1.07e-03	16	90	2	EFO_0009048
Disease	Familial primary pulmonary hypertension	HDAC5 SOX17	1.21e-03	17	90	2	C0340543
Disease	pulmonary hypertension (biomarker_via_orthology)	HDAC5 SOX17 HIF3A	1.90e-03	80	90	3	DOID:6432 (biomarker_via_orthology)
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	RET MEN1	2.23e-03	23	90	2	C1708353
Disease	brain volume measurement	CACNA1A ZFHX4 SZT2 TLE1 LOXL1 GPATCH1 ZIC3	2.31e-03	595	90	7	EFO_0006930
Disease	Intrahepatic Cholangiocarcinoma	KMT2C ROBO2	2.43e-03	24	90	2	C0345905
Disease	stomach carcinoma (is_marker_for)	KMT2C CBLB	2.43e-03	24	90	2	DOID:5517 (is_marker_for)
Disease	Extrahepatic Cholangiocarcinoma	KMT2C ROBO2	2.43e-03	24	90	2	C3805278
Disease	descending aortic diameter	SPTBN4 NFATC4 LOXL1	2.50e-03	88	90	3	EFO_0021788
Disease	Cholangiocarcinoma	KMT2C ROBO2	2.85e-03	26	90	2	C0206698

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGPRRYPGPTAEPLA	CACNA1A	2336	O00555
PGPPGLPGTSYEELL	COL17A1	1151	Q9UMD9
PLLPFYPPEGALEGS	SLC4A3	851	P48751
SPVYPGPARPASLGL	CDX1	11	P47902
LYDVPPGLRRPGPGT	BCAR1	371	P56945
PGLRRPGPGTLYDVP	BCAR1	376	P56945
LSPGRSADPLPGYAP	BEGAIN	501	Q9BUH8
LGPPDFPSLAPRYRE	CLIC3	86	O95833
LLTYVTGAPGPPSPR	ARMC5	551	Q96C12
LEGTRYPPLDSGLPP	CCDC87	366	Q9NVE4
YPPLDSGLPPLLGVV	CCDC87	371	Q9NVE4
GPGDLRLENYPIPEP	SORD	16	Q00796
TTPDGYTPELPLPLI	DSC2	216	Q02487
PGNPALYSRARLGPP	IGDCC4	996	Q8TDY8
PPRYLQSLSGPELPP	RASSF5	21	Q8WWW0
PTPGRPDPLTLYHKG	MEN1	296	O00255
SLPYLPSGTPELEVP	CHIT1	386	Q13231
PYSPLASLSGEPPGR	NFATC2	71	Q13469
TALPTAPPGLLGTPY	PCBP4	336	P57723
LYRPEPLPEVALPGS	DCHS1	476	Q96JQ0
EYLLDEGPAPGTPPR	CASKIN1	726	Q8WXD9
RPGPIVPPVYGLEVS	TRIT1	336	Q9H3H1
LLYGRESAPPPTAPF	KLF4	171	O43474
YARPLLTPAPLDSGP	KMT2C	2026	Q8NEZ4
LLDFPTLLVYPPDGP	MAP10	61	Q9P2G4
SPEPLPIPTLLVGYD	MED13L	1376	Q71F56
ERYPGGSPIPADPRK	KIAA1671	1306	Q9BY89
SPEPGGPDLLRTPLY	MGAT3	61	Q09327
PEPPGRPDGPSLLYR	HIC1	316	Q14526
PLGLAPPPRYPGSLD	HIC1	371	Q14526
YLPVRSSDTPPPGGE	LOXL1	331	Q08397
GSEEYDVPPRLSPPP	CBLB	661	Q13191
SPPGGSGSEPYKLLP	HNF4A	436	P41235
PDPYPDSTLVGLPRV	GPATCH1	626	Q9BRR8
AGPPELALLVLYPGP	AMH	156	P03971
GPPSTPGLGRYLEVL	LILRB3	431	O75022
GSDALLPGPPDLYSP	EGR4	236	Q05215
LPGPPDLYSPDLGAA	EGR4	241	Q05215
APIPFGGIYLPLEVP	OTUD7A	336	Q8TE49
SPRPGPAIPREEGLY	FAM170B	46	A6NMN3
DRVLGLYPPPPGLTE	NDOR1	151	Q9UHB4
PSPVPPLYLDDDGLP	MTMR4	1001	Q9NYA4
LPGPYGALPPGQELS	FBRS	121	Q9HAH7
YLRIPAGEAVPGPLP	HEATR5B	761	Q9P2D3
PFLIPGVSPGLIYPS	CHD6	2611	Q8TD26
GIYDVPLLGPEAPPS	EFS	251	O43281
PPPILSPVREGSGLY	MIDEAS	656	Q6PJG2
LGYPQAPPSGLERTP	KIRREL1	706	Q96J84
LLRLGDTPSPPYPAT	HCFC1R1	116	Q9NWW0
GPEPPYPLASLHEGL	FIGNL2	101	A6NMB9
PLPGPYDSRDDFPLR	HDAC5	241	Q9UQL6
PPELLLGERDYGPPI	CDK9	196	P50750
AQGPPGPPLDLAYLR	COL15A1	1006	P39059
ERYGPLLDLPELPFP	RSF1	31	Q96T23
LRPSEPFLTPYLLGP	SLC19A2	46	O60779
DGPNALRPPRGTPEY	ATP4A	86	P20648
GGPLLYRPRGPLTDP	IKZF4	431	Q9H2S9
YRPRGPLTDPGASPS	IKZF4	436	Q9H2S9
PLPPQGGLPDLDIYL	SZT2	2266	Q5T011
APPLDGYPLPTPDTS	SOX17	211	Q9H6I2
GYPLPTPDTSPLDGV	SOX17	216	Q9H6I2
PLGPYLLPSGAPERG	SEZ6L	41	Q9BYH1
TLLPGLDSYSPIPEG	PRUNE2	461	Q8WUY3
RFPLATYILPPSGDP	SSPOP	2051	A2VEC9
RASPEPGYPGEPLLG	AATK	716	Q6ZMQ8
LALGEPPPYGAAPIG	NFATC4	46	Q14934
LPSYNIRPDGPGAPR	PLEKHA4	101	Q9H4M7
PLGLGPSLLSPYSDE	HIF3A	636	Q9Y2N7
DFGYILGRDPKPLPP	PIK3C3	761	Q8NEB9
GPPTYDPALPSTPLL	NEO1	1371	Q92859
ELQPPRGLPSDYGRP	INPPL1	1151	O15357
RGLPSDYGRPLSFPP	INPPL1	1156	O15357
ESPEPLPIPTFLLGY	MED13	1326	Q9UHV7
LPYAVPPLSLPRGEA	ITGA2B	966	P08514
LAPSLEAPGPGLPAY	SPIB	91	Q01892
PILPSGPLYPGLFDI	SHANK1	2021	Q9Y566
VIPLLDPYGPAGSDP	COASY	266	Q13057
YPLPGSPLAAGVLPS	ZCCHC2	916	Q9C0B9
PGVPLYPPGLSELKV	PRR22	241	Q8IZ63
AGIPEPPSYLLFPGL	ZIC3	151	O60481
AGLRTPLAVPGPYPA	TLE1	356	Q04724
PGLGELSPYISDPAL	ZFHX4	861	Q86UP3
GISLPTAYPGLPGLP	ZFHX4	3046	Q86UP3
AILYGPPPVSGLSEP	RALGAPA1	1611	Q6GYQ0
QDGYSGPRVREPLPP	RBMXL3	231	Q8N7X1
PSLYPTVQARPGLGP	PLPPR3	466	Q6T4P5
VPTSLGLPPGPSSYL	SCAF1	1151	Q9H7N4
GLPPGPSSYLLPGSL	SCAF1	1156	Q9H7N4
PLLRPGGYERGLEPL	SPTBN4	2146	Q9H254
PPVPPLGYVSGALIS	ROBO2	1196	Q9HCK4
PRVPVGGELPTYFLP	TTC17	511	Q96AE7
VLEPPVDPGLPYRLG	WDR6	956	Q9NNW5
SGGLLPDPPRSSYLE	YLPM1	741	P49750
PDPPRSSYLESPRGP	YLPM1	746	P49750
TLGGNPYPGIPPERL	RET	946	P07949
TPGPVGLALPYAIPA	ZNF598	461	Q86UK7
LGTLPIGARYAPPPS	ZC3H7A	326	Q8IWR0
LNPRTGPEGLPYSSP	ZNF746	391	Q6NUN9
LGLPVPRYSGNPLDP	VWA8	241	A3KMH1
PPDLGLLAYEPLGPA	ZNF219	346	Q9P2Y4
LLGGEASYLGPPLTP	ZBTB46	341	Q86UZ6
PPGPTLDPLDLLPYS	ZC3H7B	341	Q9UGR2