Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

POTEF ACTB ACTG1 POTEE POTEI

2.04e-08111735GO:0098973
GeneOntologyMolecularFunctionstructural constituent of postsynapse

POTEF ACTB ACTG1 POTEE POTEI

7.68e-06321735GO:0099186
GeneOntologyMolecularFunctionstructural constituent of synapse

POTEF ACTB ACTG1 POTEE POTEI

3.02e-05421735GO:0098918
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

GDPD5 PLCB3 PLCL1 PLCH1

7.01e-05261734GO:0004435
GeneOntologyMolecularFunctionphospholipase C activity

GDPD5 PLCB3 PLCL1 PLCH1

1.09e-04291734GO:0004629
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

BEST2 SLC26A9 SLC4A3 SLC26A7

1.62e-04321734GO:0015106
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A9 SLC4A3 SLC26A7

1.71e-04131733GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A9 SLC4A3 SLC26A7

1.71e-04131733GO:0140829
GeneOntologyMolecularFunctionexoribonuclease II activity

ISG20 HELZ2

2.23e-0431732GO:0008859
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A5 EXT2 UGT1A4 UGT1A3

2.31e-04351734GO:0015020
GeneOntologyMolecularFunctionadipokinetic hormone receptor activity

ADIPOR1 CMKLR1

4.43e-0441732GO:0097003
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D7 CYP2D6

4.43e-0441732GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D7 CYP2D6

4.43e-0441732GO:0062188
GeneOntologyMolecularFunctionsteroid 21-monooxygenase activity

CYP2D7 CYP2D6

4.43e-0441732GO:0004509
GeneOntologyMolecularFunctionprogesterone 21-hydroxylase activity

CYP2D7 CYP2D6

4.43e-0441732GO:0106309
GeneOntologyMolecularFunctionhelicase activity

DHX40 MCM2 ZNFX1 FANCM DDX54 HELZ2 HELLS

4.62e-041581737GO:0004386
GeneOntologyMolecularFunctionphospholipase activity

PGAP6 GDE1 GDPD5 PLCB3 PLCL1 PLCH1

4.78e-041141736GO:0004620
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

ATP7B TRPM2 SLC30A2 SLC25A28

5.64e-04441734GO:0046915
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRR2 BEST2 SLC26A9 SLC4A3 SLC12A3 SLC26A7

7.77e-041251736GO:0015108
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRR2 ATP7B TSPOAP1 NOX5 BEST2 TRPM2 SLC26A9 SLC30A2 SLC4A3 RYR2 KCNT2 SLC12A3 SLC26A7 PKD1 SLC25A28 ATP4A

9.37e-0475817316GO:0015318
GeneOntologyMolecularFunctionATP-dependent activity

ATP7B DHX40 ACTB MCM2 ZNFX1 SMC2 FANCM ACSBG1 DDX54 HELZ2 MYO15A ATP4A SLC27A5 HELLS

9.46e-0461417314GO:0140657
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

ANK2 POTEF ACTB ACTG1 POTEE POTEI

9.53e-041301736GO:0005200
GeneOntologyMolecularFunctionglycerophosphodiester phosphodiesterase activity

GDE1 GDPD5

1.09e-0361732GO:0008889
GeneOntologyMolecularFunctionanandamide 14,15 epoxidase activity

CYP2D7 CYP2D6

1.09e-0361732GO:0062189
GeneOntologyMolecularFunctionanandamide epoxidase activity

CYP2D7 CYP2D6

1.09e-0361732GO:0062186
GeneOntologyMolecularFunctionlipase activity

PGAP6 GDE1 GDPD5 PLCB3 PLCL1 PLCH1

1.30e-031381736GO:0016298
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRR2 ATP7B TSPOAP1 NOX5 BEST2 TRPM2 SLC26A9 SLC30A2 SLC4A3 RYR2 KCNT2 SLC12A3 SLC26A7 PKD1 SLC25A28 ATP4A

1.50e-0379317316GO:0015075
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

GDE1 GDPD5 PLCB3 PLCL1 PLCH1

1.56e-03971735GO:0008081
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A5 UGT1A4 UGT1A3

1.79e-03281733GO:0001972
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ABHD17A ISG20 DCLRE1B FANCM PGAP6 GDE1 PPM1A GDPD5 DUSP26 SSH1 PTPRQ PANK4 HELZ2 PLCB3 PLCL1 PLCH1

1.79e-0380717316GO:0016788
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

GDE1 PPM1A GDPD5 DUSP26 SSH1 PTPRQ PANK4 PLCB3 PLCL1 PLCH1

2.03e-0338617310GO:0042578
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRR2 BEST2 SLC26A9 SLC4A3 SLC12A3 SLC26A7

2.05e-031511736GO:0008509
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

MGAT4B UGT1A5 EXT2 UGT1A4 UGT1A3 CERCAM

2.19e-031531736GO:0008194
GeneOntologyMolecularFunctioncalcium ion binding

FAT4 NOX5 PCDHGA7 TRPM2 CDH23 RYR2 FAT1 CDH24 FAT2 HMCN1 OTOF C1S PLCB3 DSG4 PLCH1

2.25e-0374917315GO:0005509
GeneOntologyMolecularFunctionhexosyltransferase activity

MGAT4B UGT1A5 EXT2 POMT1 UGT1A4 UGT1A3 CERCAM

2.47e-032111737GO:0016758
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC26A9 SLC4A3 SLC26A7

2.64e-03321733GO:0005452
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

BEST2 TRPM2 RYR2

2.88e-03331733GO:0005217
GeneOntologyMolecularFunctionvery long-chain fatty acid-CoA ligase activity

ACSBG1 SLC27A5

3.21e-03101732GO:0031957
GeneOntologyMolecularFunctionoxalate transmembrane transporter activity

SLC26A9 SLC26A7

3.21e-03101732GO:0019531
GeneOntologyMolecularFunctionvirion binding

HIPK2 PTX3

3.21e-03101732GO:0046790
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT4 PCDHGA7 CDH23 IGSF11 FAT1 CDH24 FAT2 HMCN1 PKD1 DSG4 IGSF9B

5.03e-0718717211GO:0007156
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GABRR2 FLNA ATP7B ANK2 TSPOAP1 NOX5 BEST2 TRPM2 SLC26A9 RGS9 SLC30A2 SLC4A3 OPA1 RYR2 AKAP9 KCNT2 SLC12A3 SLC26A7 MTOR PKD1 PLCB3 PLCH1 SLC25A28 ATP4A

4.09e-06101717224GO:0098660
GeneOntologyBiologicalProcesspostsynaptic actin cytoskeleton organization

POTEF ACTB ACTG1 POTEE POTEI

5.42e-06311725GO:0098974
GeneOntologyBiologicalProcesspostsynaptic cytoskeleton organization

POTEF ACTB ACTG1 POTEE POTEI

1.01e-05351725GO:0099188
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

FAT4 PCDHGA7 CDH23 IGSF11 FAT1 CDH24 FAT2 HMCN1 PKD1 DSG4 IGSF9B MDGA1

1.31e-0531317212GO:0098742
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GABRR2 FLNA ATP7B ANK2 TSPOAP1 NOX5 BEST2 TRPM2 SLC26A9 RGS9 SLC30A2 SLC4A3 OPA1 RYR2 AKAP9 KCNT2 SLC12A3 SLC26A7 MTOR PKD1 PLCB3 PLCH1 SLC25A28 ATP4A

1.89e-05111517224GO:0034220
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

FAT4 ACTB ACTG1 FAT1 PAFAH1B1 PKHD1

3.30e-05731726GO:0001738
GeneOntologyBiologicalProcessprotein localization to cell-cell junction

FLNA ACTB ACTG1 VCL

4.36e-05241724GO:0150105
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO1 NOMO2 NOMO3

4.61e-0591723GO:0160063
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A5 UGT1A4 UGT1A3 SORD

6.05e-05261724GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A5 UGT1A4 UGT1A3 SORD

6.05e-05261724GO:0006063
GeneOntologyBiologicalProcesssynapse organization

ABHD17A FLNA POTEF ACTB ACTG1 IGSF11 ADNP OPA1 SORT1 POTEE SSH1 PAFAH1B1 SYN1 SEPTIN11 IGSF9B POTEI MDGA1

6.23e-0568517217GO:0050808
GeneOntologyBiologicalProcesscell junction organization

ABHD17A FLNA ANK2 POTEF ACTB ACTG1 IGSF11 ADNP OPA1 SORT1 POTEE CDH24 SSH1 PAFAH1B1 PKHD1 SYN1 SEPTIN11 IGSF9B POTEI MDGA1 VCL

6.42e-0597417221GO:0034330
GeneOntologyBiologicalProcessregulation of cardiac muscle cell action potential

ANK2 SLC4A3 RYR2 AKAP9

1.08e-04301724GO:0098901
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

GABRR2 BEST2 SLC26A9 SLC4A3 SLC12A3 SLC26A7 MTOR

1.34e-041341727GO:0098661
GeneOntologyBiologicalProcessmonoatomic ion transport

GABRR2 FLNA ATP7B ANK2 TSPOAP1 NOX5 BEST2 TRPM2 CDH23 SLC26A9 RGS9 SLC30A2 SLC4A3 OPA1 RYR2 AKAP9 KCNT2 SLC12A3 SLC26A7 MTOR PKD1 PLCB3 PLCH1 SLC25A28 ATP4A

1.89e-04137417225GO:0006811
GeneOntologyBiologicalProcessserotonin biosynthetic process from tryptophan

CYP2D7 CYP2D6

2.06e-0431722GO:0006587
GeneOntologyBiologicalProcessregulation of SA node cell action potential

ANK2 RYR2

2.06e-0431722GO:0098907
GeneOntologyBiologicalProcesscell-cell adhesion

FLNA FAT4 PCDHGA7 ACTB ACTG1 CDH23 IGSF11 OPA1 FAT1 CDH24 FAT2 HMCN1 MTOR PKD1 PKHD1 CERCAM DSG4 IGSF9B MDGA1 VCL PNP

2.58e-04107717221GO:0098609
GeneOntologyBiologicalProcessbicarbonate transport

BEST2 SLC26A9 SLC4A3 SLC26A7

2.76e-04381724GO:0015701
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

FLNA ATP7B ANK2 TSPOAP1 TRPM2 CDH23 SLC26A9 EXT2 SLC30A2 SLC4A3 RYR2 SLC12A3 PKHD1 PLCB3 PLCH1 ATP4A

2.84e-0470517216GO:0055080
GeneOntologyBiologicalProcesssequestering of calcium ion

FLNA ATP7B ANK2 TRPM2 RYR2 PLCB3 PLCH1

3.03e-041531727GO:0051208
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRR2 BEST2 SLC26A9 SLC4A3 SLC12A3 SLC26A7 MTOR

3.03e-041531727GO:0098656
GeneOntologyBiologicalProcessmaintenance of location in cell

FLNA ATP7B ANK2 TRPM2 RYR2 AKAP9 PAFAH1B1 PLCB3 PLCH1

3.35e-042591729GO:0051651
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

FLNA ATP7B ANK2 TSPOAP1 NOX5 BEST2 TRPM2 RGS9 SLC30A2 OPA1 RYR2 AKAP9 KCNT2 SLC12A3 PKD1 PLCB3 PLCH1 SLC25A28 ATP4A

3.39e-0494217219GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

FLNA ATP7B ANK2 TSPOAP1 TRPM2 CDH23 SLC26A9 EXT2 SLC30A2 SLC4A3 RYR2 SLC12A3 PKHD1 PLCB3 PLCH1 ATP4A

3.42e-0471717216GO:0050801
GeneOntologyBiologicalProcesschloride transmembrane transport

GABRR2 BEST2 SLC26A9 SLC4A3 SLC12A3 SLC26A7

3.55e-041121726GO:1902476
GeneOntologyBiologicalProcessregulation of transepithelial transport

ACTB ACTG1

4.10e-0441722GO:0150111
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell action potential

ANK2 RYR2

4.10e-0441722GO:0098910
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell communication

FLNA ANK2 RYR2

5.00e-04191723GO:0086066
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell signaling

FLNA ANK2 RYR2

5.00e-04191723GO:0086026
GeneOntologyBiologicalProcessatrial cardiac muscle cell action potential

FLNA ANK2 RYR2

5.00e-04191723GO:0086014
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

6.51e-06321755GO:0035267
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

6.51e-06321755GO:0043189
GeneOntologyCellularComponentH4 histone acetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

3.62e-05451755GO:1902562
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO1 NOMO2 NOMO3

4.67e-0591753GO:0160064
GeneOntologyCellularComponentaxon

GABRR2 FLNA TSPOAP1 POTEF CYTH2 KATNB1 ACTB CNTNAP3 ACTG1 TXNRD2 ADNP OPA1 POTEE GDPD5 SSH1 PAFAH1B1 SYN1 SEPTIN11 POTEI MDGA1

5.95e-0589117520GO:0030424
GeneOntologyCellularComponentER membrane insertion complex

NOMO1 NOMO2 NOMO3

1.96e-04141753GO:0072379
GeneOntologyCellularComponentactin filament

FLNA POTEF ACTB ACTG1 POTEE POTEI VCL

2.33e-041461757GO:0005884
GeneOntologyCellularComponentpostsynaptic specialization of symmetric synapse

SEPTIN11 IGSF9B

4.14e-0441752GO:0099629
GeneOntologyCellularComponentcell-cell junction

FLNA EPPK1 ATP7B ANK2 CYTH2 ACTB ACTG1 IGSF11 FAT1 CDH24 FAT2 HMCN1 DSG4 VCL

4.70e-0459117514GO:0005911
GeneOntologyCellularComponentapical part of cell

FAT4 ATP7B ANK2 ACTG1 CDH23 SLC26A9 FAT1 SLC12A3 OTOF SLC26A7 NPC1L1 PTPRQ PKHD1 ATP4A

4.78e-0459217514GO:0045177
GeneOntologyCellularComponentcostamere

ANK2 ACTG1 VCL

7.90e-04221753GO:0043034
GeneOntologyCellularComponentcochlear hair cell ribbon synapse

CDH23 OTOF

1.02e-0361752GO:0098683
GeneOntologyCellularComponentextrinsic component of plasma membrane

ANK2 CYTH2 CDH23 RYR2 CDH24 AKAP9

1.05e-031371756GO:0019897
GeneOntologyCellularComponenthistone acetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

1.17e-03941755GO:0000123
GeneOntologyCellularComponentendoplasmic reticulum membrane

MBTPS1 CYP2D6 NOX5 UGT1A5 SLC26A9 SEC11C EXT2 POMT1 LCLAT1 RYR2 NOMO1 SORT1 UGT1A4 UGT1A3 GDPD5 OTOF NOMO2 MTOR HHAT ATG9A NOMO3 SLC27A5

1.21e-03129317522GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

MBTPS1 CYP2D6 NOX5 UGT1A5 SLC26A9 SEC11C EXT2 POMT1 LCLAT1 RYR2 NOMO1 SORT1 UGT1A4 UGT1A3 GDPD5 OTOF NOMO2 MTOR HHAT ATG9A NOMO3 SLC27A5

1.29e-03129917522GO:0098827
GeneOntologyCellularComponentdense body

ACTB ACTG1

1.42e-0371752GO:0097433
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

MBTPS1 CYP2D6 NOX5 UGT1A5 SLC26A9 SEC11C EXT2 POMT1 LCLAT1 RYR2 NOMO1 SORT1 UGT1A4 UGT1A3 GDPD5 OTOF NOMO2 MTOR HHAT ATG9A NOMO3 SLC27A5

1.68e-03132717522GO:0042175
GeneOntologyCellularComponentprotein acetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

1.83e-031041755GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

POTEF ACTB ACTG1 POTEE POTEI

2.25e-031091755GO:1902493
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle membrane

OTOF SYN1

2.41e-0391752GO:0060203
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle

OTOF SYN1

2.41e-0391752GO:0060199
GeneOntologyCellularComponentstereocilium

CDH23 PAFAH1B1 PTPRQ MYO15A

2.69e-03691754GO:0032420
GeneOntologyCellularComponentcluster of actin-based cell projections

FLNA ACTB CDH23 PAFAH1B1 NPC1L1 PTPRQ MYO15A

2.79e-032231757GO:0098862
HumanPhenoGray matter heterotopia

RALGAPA1 FLNA FAT4 KATNB1 ACTB POMT1 MTOR PAFAH1B1 TRAPPC10 PLCH1

4.84e-061296610HP:0002282
MousePhenoshort outer hair cell stereocilia

ACTB PTPRQ MYO15A

8.69e-0651353MP:0004531
MousePhenoabnormal outer hair cell stereocilia length

ACTB PTPRQ MYO15A

8.69e-0651353MP:0014411
MousePhenoabnormal cochlear hair cell stereociliary bundle morphology

FAT4 ACTB ACTG1 CDH23 OTOF PTPRQ MYO15A

2.76e-05911357MP:0004521
MousePhenoabnormal outer hair cell stereociliary bundle morphology

FAT4 ACTB ACTG1 CDH23 PTPRQ MYO15A

4.86e-05681356MP:0004527
MousePhenoincreased susceptibility to age-related hearing loss

ACTB ACTG1 CDH23 PTPRQ

6.39e-05231354MP:0004748
MousePhenodecreased cochlear hair cell stereocilia number

ACTB ACTG1 CDH23 PTPRQ

1.05e-04261354MP:0004523
DomainActin_CS

POTEF ACTB ACTG1 POTEE POTEI

2.24e-07161685IPR004001
DomainACTINS_2

POTEF ACTB ACTG1 POTEE POTEI

3.15e-07171685PS00432
DomainActin/actin-like_CS

POTEF ACTB ACTG1 POTEE POTEI

4.32e-07181685IPR020902
DomainACTINS_ACT_LIKE

POTEF ACTB ACTG1 POTEE POTEI

5.83e-07191685PS01132
Domain-

GDE1 GDPD5 PLCB3 PLCL1 PLCH1

2.55e-062516853.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

GDE1 GDPD5 PLCB3 PLCL1 PLCH1

2.55e-06251685IPR017946
DomainDUF2012

NOMO1 NOMO2 NOMO3

2.84e-0641683PF09430
DomainDUF2012

NOMO1 NOMO2 NOMO3

2.84e-0641683IPR019008
DomainActin

POTEF ACTB ACTG1 POTEE POTEI

7.80e-06311685IPR004000
DomainActin

POTEF ACTB ACTG1 POTEE POTEI

7.80e-06311685PF00022
DomainACTIN

POTEF ACTB ACTG1 POTEE POTEI

7.80e-06311685SM00268
DomainCadherin

FAT4 PCDHGA7 CDH23 KIAA0319 FAT1 CDH24 FAT2 DSG4

1.15e-051181688IPR002126
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

3.87e-0581683IPR013784
DomainCadherin_CS

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

5.80e-051091687IPR020894
DomainCADHERIN_1

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

7.30e-051131687PS00232
DomainCadherin

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

7.30e-051131687PF00028
DomainCADHERIN_2

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

7.72e-051141687PS50268
Domain-

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

7.72e-0511416872.60.40.60
DomainCA

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

8.15e-051151687SM00112
DomainCadherin-like

FAT4 PCDHGA7 CDH23 FAT1 CDH24 FAT2 DSG4

8.61e-051161687IPR015919
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

1.91e-04131683IPR014766
Domain-

NOMO1 NOMO2 NOMO3

1.91e-041316832.60.40.1120
Domain-

FAT4 CNTNAP3 ADGRG4 FAT1 FAT2 PTX3

2.17e-049516862.60.120.200
DomainIg-like_fold

FLNA TSPOAP1 REL IGSF11 TGM6 IL18R1 NOMO1 KIAA0319 HMCN1 NOMO2 VSTM2L WFIKKN2 PKHD1 IGSF9B MDGA1 NOMO3 ADGRA3

2.18e-0470616817IPR013783
DomainEF-hand_like

PLCB3 PLCL1 PLCH1

3.00e-04151683PF09279
DomainPI-PLC-Y

PLCB3 PLCL1 PLCH1

3.00e-04151683PF00387
DomainPLCYc

PLCB3 PLCL1 PLCH1

3.00e-04151683SM00149
DomainPLipase_C_Pinositol-sp_Y

PLCB3 PLCL1 PLCH1

3.00e-04151683IPR001711
DomainPIPLC_Y_DOMAIN

PLCB3 PLCL1 PLCH1

3.00e-04151683PS50008
DomainPI-PLC_fam

PLCB3 PLCL1 PLCH1

3.00e-04151683IPR001192
DomainPLC_EF-hand-like

PLCB3 PLCL1 PLCH1

3.00e-04151683IPR015359
Domain-

FLNA TSPOAP1 REL IGSF11 TGM6 IL18R1 NOMO1 HMCN1 NOMO2 VSTM2L WFIKKN2 PKHD1 IGSF9B MDGA1 NOMO3 ADGRA3

3.28e-04663168162.60.40.10
DomainLAM_G_DOMAIN

FAT4 CNTNAP3 FAT1 FAT2

3.67e-04381684PS50025
DomainCarboxyPept-like_regulatory

NOMO1 NOMO2 NOMO3

4.43e-04171683IPR008969
DomainLaminin_G_2

FAT4 CNTNAP3 FAT1 FAT2

4.48e-04401684PF02210
DomainPI-PLC-X

PLCB3 PLCL1 PLCH1

5.28e-04181683PF00388
DomainPLCXc

PLCB3 PLCL1 PLCH1

5.28e-04181683SM00148
DomainPIPLC_X_DOMAIN

PLCB3 PLCL1 PLCH1

6.23e-04191683PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB3 PLCL1 PLCH1

6.23e-04191683IPR000909
DomainLamG

FAT4 CNTNAP3 FAT1 FAT2

6.48e-04441684SM00282
DomainConA-like_dom

FAT4 CNTNAP3 ADGRG4 RYR2 FAT1 FAT2 PTX3 MDGA1

8.41e-042191688IPR013320
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

8.44e-04211683PF00201
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

8.44e-04211683PS00375
DomainUDP_glucos_trans

UGT1A5 UGT1A4 UGT1A3

8.44e-04211683IPR002213
DomainPKD/REJ-like

KIAA0319 PKD1

1.18e-0361682IPR002859
DomainREJ

KIAA0319 PKD1

1.18e-0361682PF02010
DomainGP_PDE_dom

GDE1 GDPD5

1.64e-0371682IPR030395
DomainGlyceroP-diester-Pdiesterase

GDE1 GDPD5

1.64e-0371682IPR004129
DomainGDPD

GDE1 GDPD5

1.64e-0371682PF03009
DomainGP_PDE

GDE1 GDPD5

1.64e-0371682PS51704
DomainLaminin_G

FAT4 CNTNAP3 FAT1 FAT2

1.84e-03581684IPR001791
PathwayWP_GPR40_PATHWAY

PKD1 PLCB3 PLCL1 PLCH1

9.26e-06151324M39526
PathwayREACTOME_ASPIRIN_ADME

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

6.04e-05451325MM15694
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY

ACTB ACTG1 VCL

6.47e-0591323M47725
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND

ACTB ACTG1 CDH23 OTOF SYN1 MYO15A

8.27e-05771326M41822
Pubmed

Identification of a novel actin isoform in hepatocellular carcinoma.

POTEF ACTB ACTG1 POTEE POTEI

9.04e-0915176516824795
Pubmed

Impact of altered actin gene expression on vinculin, talin, cell spreading, and motility.

ACTB ACTG1 VCL

1.27e-07317637646816
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

1.27e-073176336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

1.27e-073176325576386
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

FLNA ACTG1 MCM2 PFAS SMC2 NOMO1 NOMO2 SUPT16H HELZ2 SEPTIN11 NOMO3 VCL

2.14e-073441761230333137
Pubmed

β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance.

ACTB ACTG1 CDH23

5.08e-074176320976199
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

5.08e-074176331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

5.08e-07417639267806
Pubmed

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.

FLNA ACTB NOMO1 KLK4 NOMO3 SORD

7.49e-0762176615862967
Pubmed

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

FLNA ACTB ACTG1

2.52e-066176312679033
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA ACLY DHX40 FAT2 OTOF SUPT16H DDX54 PLCH1 VPS13B

3.32e-06234176936243803
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT1 FAT2

4.39e-067176316059920
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO1 NOMO2 NOMO3

7.00e-068176315257293
Pubmed

Defining the membrane proteome of NK cells.

ABHD17A FLNA ATP7B ACLY HTATIP2 KATNB1 ACTB RNF149 ACTG1 EXT2 OPA1 LCLAT1 NOMO1 NUP205 ADIPOR1 MTOR DDX54 HELZ2 ATG9A

8.18e-0611681761919946888
Pubmed

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.

MCM2 SMC2 ADNP SUPT16H

8.69e-0626176434162889
Pubmed

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

FLNA ACTB ACTG1 VCL

8.69e-0626176423382103
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANK2 CYTH2 ACTB DPYSL4 ZNFX1 SMC2 ADNP OPA1 KIAA0319 AKAP9 SSH1 MTOR SUPT16H SYN1 SEPTIN11 PLCL1 RASAL2

8.85e-069631761728671696
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA CAND2 ACLY DHX40 MCM2 PFAS EXT2 SMC2 OPA1 NOMO1 NUP205 DUSP26 SSH1 TELO2 MTOR DDX54 VCL

1.02e-059741761728675297
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A5 UGT1A4 UGT1A3

1.05e-059176322511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A5 UGT1A4 UGT1A3

1.05e-05917631339448
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO1 NOMO2 NOMO3

1.05e-059176336261522
Pubmed

The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.

EPPK1 POTEF ACTB ACTG1 POTEE PNP

1.24e-05100176621800051
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A5 UGT1A4 UGT1A3

1.49e-0510176323642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A5 UGT1A4 UGT1A3

1.49e-0510176311465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A5 UGT1A4 UGT1A3

1.49e-0510176323371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A5 UGT1A4 UGT1A3

1.49e-0510176322558097
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

ACTB NOMO1 NOMO2 NOMO3

1.79e-0531176419136429
Pubmed

HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells.

ACTB ACTG1 VCL

2.04e-0511176314597672
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO1 NOMO2 NOMO3

2.04e-0511176332820719
Pubmed

Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.

ACTB ACTG1

2.55e-052176221778137
Pubmed

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.

ACTB ACTG1

2.55e-052176222366783
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A5 UGT1A3

2.55e-05217628068691
Pubmed

Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair?

MTOR PKD1

2.55e-052176217102641
Pubmed

Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.

ACTB ACTG1

2.55e-052176232588558
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome.

ACTB ACTG1

2.55e-052176227625340
Pubmed

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

UGT1A4 UGT1A3

2.55e-052176224641623
Pubmed

Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.

CYP2D7 CYP2D6

2.55e-052176225808902
Pubmed

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

CYP2D7 CYP2D6

2.55e-052176211207030
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

2.55e-052176219669888
Pubmed

Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.

ACTB ACTG1

2.55e-05217623221869
Pubmed

The T cell receptor from an influenza-A specific murine CTL clone.

TRBV12-4 TRBV12-3

2.55e-05217622784852
Pubmed

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.

PKD1 PKHD1

2.55e-052176211919560
Pubmed

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

CYP2D7 CYP2D6

2.55e-05217623123997
Pubmed

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.

ACTB ACTG1

2.55e-052176221502360
Pubmed

The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.

ACTB ACTG1

2.55e-05217626686106
Pubmed

Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.

ACTB ACTG1

2.55e-0521762213279
Pubmed

The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.

ACTB ACTG1

2.55e-052176233334799
Pubmed

Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families.

OTOF MYO15A

2.55e-052176237189200
Pubmed

MCM2 and TIP30 are prognostic markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of the gallbladder.

HTATIP2 MCM2

2.55e-052176227748889
Pubmed

β-Actin specifically controls cell growth, migration, and the G-actin pool.

ACTB ACTG1

2.55e-052176221900491
Pubmed

Interaction between superantigen and T-cell receptor Vbeta element determines levels of superantigen-dependent cell-mediated cytotoxicity of CD8(+) T cells in induction and effector phases.

TRBV12-4 TRBV12-3

2.55e-052176219659929
Pubmed

Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.

TGM6 FAT2

2.55e-052176229053796
Pubmed

Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.

ACTB ACTG1

2.55e-052176219638415
Pubmed

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.

CDH23 OTOF

2.55e-052176217967520
Pubmed

Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.

ACTB ACTG1

2.55e-05217623335520
Pubmed

Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

ACTB ACTG1

2.55e-05217629288906
Pubmed

High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.

ACTB ACTG1

2.55e-05217621577857
Pubmed

Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.

CYP2D7 CYP2D6

2.55e-052176211032406
Pubmed

Clinicopathologic significance of minichromosome maintenance protein 2 and Tat-interacting protein 30 expression in benign and malignant lesions of the gallbladder.

HTATIP2 MCM2

2.55e-052176221543106
Pubmed

Baraitser-Winter Cerebrofrontofacial Syndrome

ACTB ACTG1

2.55e-052176226583190
Pubmed

Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.

ACTB ACTG1

2.55e-052176232326615
Pubmed

Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.

ACTB ACTG1

2.55e-052176223756437
Pubmed

Vinculin and metavinculin: oligomerization and interactions with F-actin.

ACTB VCL

2.55e-052176223466368
Pubmed

Pathogenicity analysis of novel variations in Chinese Han patients with polycystic kidney disease.

PKD1 PKHD1

2.55e-052176228578020
Pubmed

Whole Exome Sequencing Is the Minimal Technological Approach in Probands Born to Consanguineous Couples.

KATNB1 FAT1

2.55e-052176234202629
Pubmed

Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.

ACTB ACTG1

2.55e-05217628482333
Pubmed

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.

ACTB ACTG1

2.55e-052176229265728
Pubmed

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

ACTB ACTG1

2.55e-052176222246323
Pubmed

A conserved sequence in the T-cell receptor beta-chain promoter region.

TRBV12-4 TRBV12-3

2.55e-05217623259318
Pubmed

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

CYP2D7 CYP2D6

2.55e-052176219594327
Pubmed

Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.

ACTB ACTG1

2.55e-05217622837653
Pubmed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.

CYP2D7 CYP2D6

2.55e-052176226297049
Pubmed

Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.

ACTB ACTG1

2.55e-052176232349449
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.

ACTB ACTG1

2.55e-052176232506774
Pubmed

Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.

ACTB ACTG1

2.55e-052176220847274
Pubmed

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.

CYP2D7 CYP2D6

2.55e-052176215051713
Pubmed

N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.

UGT1A4 UGT1A3

2.55e-052176214570768
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A5 UGT1A4 UGT1A3

2.71e-0512176319419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A5 UGT1A4 UGT1A3

2.71e-0512176311434514
Pubmed

Genetic Hearing Loss Overview

ACTG1 CDH23 OTOF PTPRQ MYO15A

2.91e-0570176520301607
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA EPPK1 ACLY PFAS ADNP TTF1 NUP205 MTOR DDX54 HELZ2 WDR12 VCL PNP

3.11e-056531761322586326
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNA EPPK1 GTPBP6 ACLY ACTB RNF149 ACTG1 MCM2 EXT2 FAT1 NOMO2 PAFAH1B1 SEPTIN11 CERCAM WDR12 ATG9A PNP SORD HELLS

3.46e-0512971761933545068
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A5 UGT1A4 UGT1A3

3.51e-0513176322085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A5 UGT1A4 UGT1A3

3.51e-0513176325246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A5 UGT1A4 UGT1A3

4.45e-0514176321646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A5 UGT1A4 UGT1A3

4.45e-0514176310836148
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A5 UGT1A4 UGT1A3

4.45e-051417639295054
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A5 UGT1A4 UGT1A3

4.45e-0514176314672974
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLNA ANK2 GTPBP6 PCDHGA7 POTEF ACTB ACTG1 REL SMC2 SLC30A2 SLC4A3 RYR2 NUP205 SPATC1 POTEE SLC22A14 SUPT16H PKHD1 POTEI PLCH1

4.57e-0514421762035575683
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 FLNA CRYBG2 MGAT4B EPPK1 GTPBP6 PFAS MIB2 TXNRD2 GDPD5 FAT1 SSH1 MTOR PKD1 HELZ2 HMGXB3 ATG9A

5.02e-0511051761735748872
Pubmed

SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons.

ACTB ACTG1 VCL

5.54e-0515176324623780
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

THEMIS2 ABHD17A CAND2 CDH23 ISG20 TGM6 DUSP26 SMYD4 AKAP9 MTOR WFIKKN2 TRAPPC10 HMGXB3 CFAP61 MYO15A SLC25A28 MTRF1L RASAL2

6.44e-0512421761830973865
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

CAND2 ACTB PFAS OPA1 NOMO1 SORT1 TELO2 NOMO2 MTOR PANK4 DDX54 NOMO3

6.63e-056061761236538041
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A5 UGT1A4 UGT1A3

6.80e-0516176319414484
Pubmed

Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines.

MTOR PKD1

7.61e-053176231251475
Pubmed

Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.

ACTB ACTG1

7.61e-05317629245787
Pubmed

WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway.

SORT1 SLC12A3

7.61e-053176219875813
Pubmed

Characterization of PKD protein-positive exosome-like vesicles.

PKD1 PKHD1

7.61e-053176219158352
Pubmed

Analysis of the T cell receptor (TcR) regions in the NOD, NON and CTS mouse strains define new TcR V alpha haplotypes and new deletions in the TcR V beta region.

TRBV12-4 TRBV12-3

7.61e-05317621532150
Pubmed

Angiostatin and plasminogen share binding to endothelial cell surface actin.

ACTB ACTG1

7.61e-053176215746964
InteractionSHBG interactions

FLNA ACTB NOMO1 KLK4 NOMO3 TMEM236 SORD

1.79e-06691697int:SHBG
InteractionACTG2 interactions

POTEF ACTB ACTG1 MCM2 POTEE POTEI

3.30e-06491696int:ACTG2
InteractionSCIN interactions

POTEF ACTB ACTG1 SSH1 ATG9A POTEI

8.98e-06581696int:SCIN
GeneFamilyCadherin related

FAT4 CDH23 FAT1 FAT2

4.39e-0617122424
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEE POTEI

8.16e-05131223685
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB3 PLCL1 PLCH1

2.68e-04191223832
GeneFamilyActins

ACTB ACTG1

6.66e-0461222929
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGSF11 HMCN1 WFIKKN2 IGSF9B MDGA1 ADGRA3

7.85e-041611226593
GeneFamilyActins|Deafness associated genes

ACTG1 CDH23 OTOF PTPRQ MYO15A

1.01e-0311312251152
GeneFamilyAnkyrin repeat domain containing

ASZ1 ANK2 POTEF MIB2 POTEE KANK4 POTEI

1.28e-032421227403
GeneFamilyUDP glucuronosyltransferases

UGT1A5 UGT1A4 UGT1A3

1.29e-03321223363
GeneFamilyUPF1 like RNA helicases

ZNFX1 HELZ2

2.39e-031112221169
CoexpressionGSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

MGAT4B ACLY CYTH2 ACTG1 DOK2 ARL5B BCO2 VCL PNP

2.73e-061751749M8892
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 ANK2 NCKAP5 RYR2 SORT1 BCO2 PLCL1 CFAP61 VCL

7.99e-081931769dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 FAT1 HMCN1 PTPRQ PKHD1 PLCH1 MYO15A

7.27e-0718417682cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 FAT1 HMCN1 PTPRQ PKHD1 PLCH1 MYO15A

7.27e-0718417682b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 FAT1 HMCN1 PTPRQ PKHD1 PLCH1 MYO15A

7.27e-071841768ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

DOCK3 ANK2 NCKAP5 RYR2 SH3RF2 PLCL1 CFAP61 VCL

8.90e-0718917689c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRR2 CRYBG2 RGSL1 OTOF NPC1L1 PTPRQ PKHD1 GAPDHS

1.04e-061931768315840bc48899f3a36d57b19197509de19716e3d
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GABRR2 RNF149 MCM2 ADNP WFIKKN2 WDR12 HELLS

2.29e-0615017677bc61eb4b8c4a1909f4b7bcd1c6a88ef46102669
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS9 TRPM2 RGS9 SLC4A3 OTOF VSTM2L SRRM3

7.07e-0617817671bddbc083c36657bd6910f7466126ab325e88176
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS9 TRPM2 RGS9 SLC4A3 OTOF VSTM2L SRRM3

7.07e-061781767a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

REL ISG20 ARL5B PTX3 SLC25A28 VPS13B PNP

9.09e-061851767a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

TFAP2D CDH24 SLC26A7 PTX3 PTPRQ

9.14e-067117657623b110bc3db0f5b99803c8fbb881ae8846b817
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A FLNA TRPM2 ACTG1 PGAP6 GDE1 VCL

9.75e-0618717678c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

TSPOAP1 RUBCNL NCKAP5 ISG20 SH3RF2 PARM1 FAM149A

1.01e-05188176747bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellControl-PLT_3|World / Disease Group and Platelet Clusters

ABHD17A FLNA MGAT4B ACTB ACTG1 ACSBG1 VCL

1.04e-051891767f65c261fe25479e900d5ed1a0d25a9dec302a57b
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

MCM2 SMC2 LCLAT1 NUP205 SUPT16H CDT1 HELLS

1.08e-05190176784ee185939bdefb10705b621a70da27701eadcee
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

FLNA RNF149 ZNFX1 ISG20 OTOF HELZ2 ELF2

1.24e-051941767d1366b169d14011194e61d16b6b0953349febc78
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 ANK2 NCKAP5 RYR2 BCO2 PLCL1 CFAP61

1.28e-051951767f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A FLNA TSPOAP1 HIPK2 RGS9 MIB2 TRAPPC10

1.37e-051971767f84263c5aaf3a5cd46d6e06358e8de6c6e6eaa3b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGSL1 ACTB CDH23 REL ZNFX1 POTEE PNP

1.37e-051971767b597c292fc1cb381a4325fed15a32966c38def28
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A FLNA FAT4 HIPK2 ACTG1 MIB2 DOK2

1.41e-051981767716c27d2a37b5f865b9d191e1851917340b400af
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM2 SEC11C SMC2 NOMO1 CDT1 PARM1 HELLS

1.41e-0519817672d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A FLNA FAT4 HIPK2 ACTG1 MIB2 DOK2

1.41e-051981767b12914c3c5b8dd628cb456cb40283c5016641872
ToppCellmild-Lymphocytic-NK_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABHD17A FLNA TSPOAP1 HIPK2 RGS9 CERCAM CMKLR1

1.41e-051981767dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCell(2)_NK/T-(20)_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

ABHD17A FLNA TSPOAP1 ACTB RGS9 DOK2 CMKLR1

1.41e-0519817672e4851e49457940e841660c5d781499ffb4a2bf1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A FLNA FAT4 HIPK2 ACTG1 MIB2 DOK2

1.41e-0519817671a189b2b213099505c5d871fb8aedd55a97d44e0
ToppCell(2)_NK/T-(200)_CD56+_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

ABHD17A FLNA TSPOAP1 ACTB RGS9 DOK2 CMKLR1

1.41e-05198176703477a6356a3c08c6e723165c0aac3464ef01667
ToppCellLPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_only / Treatment groups by lineage, cell group, cell type

ACTB SEC11C RGS9 ISG20 DOK2 SEPTIN11 HELLS

1.46e-051991767b62a756b5472972156d05051a58671a58bef1f16
ToppCellCD8+_Memory_T_cell-CV-2|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ACTB ACTG1 MCM2 SEC11C WDR12 PNP HELLS

1.46e-0519917671e33d8e2e0d6a54ef6e2e13f986e19fd209275a8
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLNA RYR2 FAT1 KCNT2 PLCL1 CMKLR1 VCL

1.51e-052001767c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

ANK2 HIPK2 SLC12A3 SLC26A7 PKHD1 SEPTIN11 PLCL1

1.51e-0520017671f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellPBMC-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

FLNA OTOF NOMO2 PLCB3 ATG9A

1.74e-058117656d1e524f000b71c935359afc801a1d31f218fec8
ToppCellE17.5-Hematopoietic-Erythroid|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPOAP1 ISG20 TXNRD2 ADIPOR1 SYN1

1.85e-05821765e0b12b9fb3cd56902b068dc0d921241481aa70a9
ToppCellE17.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPOAP1 ISG20 TXNRD2 ADIPOR1 SYN1

1.85e-058217658917c6fd4a6e3cb7a3a2af489ccc3fdc55c26698
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 CYTH2 TRPM2 CDT1 MYO15A PARM1

2.17e-051421766a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 CYTH2 TRPM2 CDT1 MYO15A PARM1

2.17e-051421766d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FLNA ASZ1 ZNFX1 ISG20 FAT1 VCL

2.35e-0514417660b94d978262a826c9254145aa98c6c30240243f9
ToppCellBLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ABHD17A FLNA ACTB HIPK2 ACTG1 DOK2

2.44e-0514517666dd81d53d006fcc206a10969374a11c372f92133
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 RGSL1 BEST2 PTPRQ PKHD1 MYO15A

2.44e-05145176696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP7B KATNB1 MCM2 SMC2 NOMO1 NOMO3

3.30e-0515317664eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP7B KATNB1 MCM2 SMC2 NOMO1 NOMO3

3.30e-05153176626b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP7B KATNB1 MCM2 SMC2 NOMO1 NOMO3

3.30e-0515317660f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM2 SEC11C DOK2 FANCM IL18R1 HELLS

4.09e-05159176695128a2367ff2a639b21913c0350924c174faef8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTB SEC11C DOK2 IL18R1 ACSBG1 SEPTIN11

4.09e-0515917665c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 KCNT2 HMCN1 PTPRQ PKHD1 C1S

4.24e-051601766c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 KCNT2 HMCN1 PTPRQ PKHD1 C1S

4.24e-05160176625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM2 IL18R1 BCO2 CDT1 PARM1 HELLS

4.39e-0516117661670108afc0af90861eb80a84e59995571c0da1b
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM2 IL18R1 BCO2 CDT1 PARM1 HELLS

4.39e-0516117661d446f5ba57d84949823a35cbedaee8f448fe40f
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGAPA1 TRPM2 MIB2 IGSF11 BCO2 IGSF9B

4.86e-051641766b895674ed2df87db8fbfb30b7e31620945588491
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

DOCK3 FLNA ACTB POTEE WFIKKN2 PARM1

5.03e-051651766531804467601e1ee1f771cffa21501f6d464ae10
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM2 RNF149 ADNP GDPD5 VSTM2L PLCH1

5.38e-0516717669efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM2 RNF149 ADNP GDPD5 VSTM2L PLCH1

5.38e-051671766904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTATIP2 CDH23 SEC11C ISG20 DCLRE1B SLC12A3

5.75e-051691766e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTATIP2 CDH23 SEC11C ISG20 DCLRE1B SLC12A3

5.75e-0516917663167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TELO2 CERCAM L3HYPDH ATG9A FAM149A HELLS

5.94e-051701766b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 ANK2 RYR2 BCO2 PLCL1 CFAP61

5.94e-0517017663f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 MCM2 SMC2 PLCH1 PARM1 HELLS

6.13e-0517117661eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CRYBG2 ACTB F8 VSTM2L SEPTIN11 POTEI

6.13e-051711766bdd30100b74e012eec3090799c22635aa57fa91d
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Habenula_(inferomedial_and_lateral))-|Thalamus / BrainAtlas - Mouse McCarroll V32

SLC26A7 PTX3 PTPRQ SLC27A5

6.14e-05541764c74878f5c7a20aeb813cc8f05a71216262c4dcad
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Habenula_(inferomedial_and_lateral))|Thalamus / BrainAtlas - Mouse McCarroll V32

SLC26A7 PTX3 PTPRQ SLC27A5

6.14e-05541764a2669b3f714c50fd51f7f32ea893282333f6ddac
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MCM2 SMC2 SMYD4 CDT1 PLCH1 HELLS

6.33e-0517217667c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTATIP2 CDH23 SEC11C ISG20 DCLRE1B MDGA1

6.54e-05173176660e427f6c7d953cef5f692043670ff0b49cdce72
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGAPA1 POMT1 SMC2 HHAT MED25 HELLS

6.75e-051741766c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTATIP2 CDH23 SEC11C ISG20 DCLRE1B MDGA1

6.75e-051741766c92eec5a14ca5269673582dd115ead8516e64c3e
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGAPA1 POMT1 SMC2 HHAT MED25 HELLS

6.75e-05174176672df66319f6efbd88ecf439013d97409fbf3cb52
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAND2 PCDHGA7 EXT2 TELO2 PANK4 PLCL1

6.75e-05174176655cc8300489d11322724159ec7d0e1d32a702e91
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

DOCK3 ANK2 DPYSL4 CDH24 GAPDHS SRRM3

6.97e-0517517668d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

DOCK3 ANK2 DPYSL4 CDH24 GAPDHS SRRM3

6.97e-0517517664db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

SLC4A3 RYR2 KLK4 CERCAM SRRM3 FAM149A

7.19e-051761766852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SLC4A3 RYR2 KLK4 CERCAM SRRM3 FAM149A

7.19e-051761766d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell3'_v3-blood-Lymphocytic_B_plasma-Plasmablasts|blood / Manually curated celltypes from each tissue

SEC11C ZNF215 SMC2 CDT1 PARM1 HELLS

7.90e-0517917667d3bd1f9e126a4a9e0a84720a6cc0b3d235e65ee
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3 HMCN1 NOMO2 SH3RF2 SLC22A14 APCDD1L

7.90e-0517917668c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA POTEF ACTB POTEE POTEI VCL

8.14e-051801766fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HIPK2 RYR2 NOMO1 BCO2 PANK4 PARM1

8.14e-0518017668e96f8646c002768b272359af485dc0ab57e0ccd
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA POTEF ACTB POTEE POTEI VCL

8.14e-051801766beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAND2 ANK2 MIB2 C1S PARM1 HELLS

8.39e-051811766274c0b768925cd5804483303f8c5ebd17a534c41
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

CRYBG2 NCKAP5 IL18R1 SLC4A3 PARM1 FAM149A

8.39e-0518117665a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 RYR2 KCNT2 HMCN1 C1S MDGA1

8.39e-051811766b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 ANK2 RYR2 BCO2 PLCL1 CFAP61

8.39e-051811766719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

THEMIS2 KATNB1 ACTB HIPK2 ACTG1 TRAPPC10

8.65e-051821766c6172aca2475bf0948a78e39f0dae6388504a915
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 NCKAP5 LCLAT1 RYR2 SORT1 BCO2

8.65e-051821766287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 HIPK2 RYR2 FAT1 KCNT2 ADGRA3

8.65e-051821766ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RUBCNL ZNFX1 ISG20 APCDD1L HELZ2 SLC25A28

8.92e-051831766dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

CRYBG2 ISG20 IL18R1 SLC4A3 PARM1 FAM149A

9.19e-051841766b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

TSPOAP1 RUBCNL ISG20 SH3RF2 PARM1 FAM149A

9.19e-051841766c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

TSPOAP1 RUBCNL NCKAP5 SH3RF2 PARM1 FAM149A

9.19e-05184176642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 ANK2 SLC4A3 RYR2 BCO2 CFAP61

9.19e-051841766e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HIPK2 CDH23 NCKAP5 HHAT KANK4 SEPTIN11

9.47e-0518517661ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

NCKAP5 KCNT2 SH3RF2 VSTM2L PTPRQ RASAL2

9.47e-05185176632b4e68e551d435a732f253f6ad83408c759a642
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FAT4 HIPK2 NCKAP5 RYR2 HHAT KANK4

9.75e-0518617667def03dd856b765bd3f493288641981c4f7fd26e
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ANK2 NCKAP5 SH3RF2 VSTM2L KANK4 VCL

1.00e-041871766f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 DOCK3 DOK2 FAT2 SYN1 SLC25A28

1.00e-041871766d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

DOCK3 NCKAP5 LCLAT1 SH3RF2 PLCL1 CFAP61

1.00e-04187176678cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

FLNA RYR2 SORT1 RASAL2 VCL PARM1

1.03e-04188176634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK2 CNTNAP3 SEC11C POTEI SRRM3 FAM149A

1.03e-041881766c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

FLNA ACTB HIPK2 SORT1 IGSF9B PARM1

1.03e-0418817669ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 SLC30A2 TGFBRAP1 ATG9A MDGA1

1.06e-041181765c351e465ece4f3767b2c19e695eca3c263c68777
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK2 RYR2 FAT1 KCNT2 PLCL1

1.13e-0419117667853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD17A RUBCNL ACTB REL DDX54 SEPTIN11

1.13e-04191176610644258b97f9c99eb0e199b64b970f6b986aa41
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

TSPOAP1 RUBCNL NCKAP5 SH3RF2 PARM1 FAM149A

1.13e-0419117663480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD17A RUBCNL ACTB REL DDX54 SEPTIN11

1.13e-041911766408942fc8db939239aeee6ae07a21362133c9e2e
DrugN-benzylformamide

CYP2D7 CYP2D6 UGT1A5 F8 UGT1A4 UGT1A3 SUPT16H SORD

1.10e-07761728CID000080654
Drug9-OH-risperidone

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

2.48e-07191725CID000475100
DrugBenzamidoxime hydrochloride

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

4.28e-07211725CID000069186
Drugtritanol

UGT1A5 UGT1A4 UGT1A3 PNP

2.13e-06131724CID000006457
Drugp-nitroanisole

CYP2D7 CYP2D6 NOX5 UGT1A5 UGT1A4 UGT1A3 SORD

6.34e-06921727CID000007485
Drug6beta-hydroxytestosterone

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

8.32e-06371725CID000065543
DrugAC1MRGT8

CYP2D7 CYP2D6 UGT1A5 MC2R UGT1A4 UGT1A3

1.16e-05671726CID003517815
Drugimipramine

GABRR2 CYP2D7 CYP2D6 TSPOAP1 UGT1A5 UGT1A4 UGT1A3 SYN1 PLCB3 PLCH1

1.26e-0523517210CID000003696
Drugtestosterone glucuronide

UGT1A5 MC2R OPA1 UGT1A4 UGT1A3

1.40e-05411725CID000108192
Drug1h1q

DOCK3 CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

1.50e-05701726CID000001540
Drug3,4-dihydroxymethamphetamine

CYP2D7 CYP2D6 TSPOAP1

2.31e-0581723CID000161126
Drugbenzyloxyresorufin

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3 SORD

2.79e-05781726CID000114982
DrugAC1Q7AUJ

CYP2D7 CYP2D6 NOX5 UGT1A5 UGT1A4 UGT1A3 SORD

3.07e-051171727CID000003303
Drugsodium

GABRR2 ATP7B ANK2 NOX5 TRPM2 ACTB ACTG1 SLC26A9 SLC4A3 RYR2 PPM1A NOMO1 KLK4 AKAP9 KCNT2 SLC12A3 SLC26A7 MTOR PKD1 ATP4A

3.19e-0594417220CID000000923
Drugbenzphetamine

CYP2D7 CYP2D6 NOX5 UGT1A5 UGT1A4 UGT1A3 SORD

3.42e-051191727CID000002341
DrugAC1MRQNQ

UGT1A5 UGT1A4 UGT1A3

3.44e-0591723CID003522271
DrugDHPASiU

UGT1A5 UGT1A4 UGT1A3

3.44e-0591723CID000197602
Drug3-iodophenol

UGT1A5 UGT1A4 UGT1A3

3.44e-0591723CID000012272
DrugAC1L4J7U

UGT1A5 UGT1A4 UGT1A3

3.44e-0591723CID000186631
DrugChebi:32663

UGT1A5 UGT1A4 UGT1A3

3.44e-0591723CID005460873
Druglamotrigine

CYP2D6 MC2R UGT1A4 UGT1A3

3.51e-05251724ctd:C047781
Drugniflumic acid

BEST2 UGT1A5 MC2R SLC26A9 UGT1A4 UGT1A3 PNP

4.69e-051251727CID000004488
Drugtangeretin

UGT1A5 REL ISG20 UGT1A4 UGT1A3

5.44e-05541725CID000068077
DrugN-hydroxy-4-aminobiphenyl

DOCK3 UGT1A5 UGT1A4 UGT1A3

5.59e-05281724CID000081261
Drugcupreidine

CYP2D7 CYP2D6

5.67e-0521722CID000051196
Drugafloqualone

UGT1A4 UGT1A3

5.67e-0521722ctd:C033541
Drug3-methoxyphenethylamine

CYP2D7 CYP2D6

5.67e-0521722CID000074866
DrugAC1L1JAL

UGT1A5 PPM1A UGT1A4 UGT1A3

6.45e-05291724CID000004954
DrugInvader

UGT1A5 CDH23 EXT2 UGT1A4 UGT1A3

6.49e-05561725CID006442259
Drug4-nitrophenyl)imidazole

UGT1A5 UGT1A4 UGT1A3

6.69e-05111723CID000123155
DrugAC1O5XMV

UGT1A5 UGT1A4 UGT1A3

6.69e-05111723CID006442661
Drugthrombin receptor-activating peptide SFLLRNPNDKY

FLNA ACTB ACTG1 VCL

7.39e-05301724ctd:C096900
Drug2-naphthol

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3 KLK4

7.54e-05931726CID000008663
Drugmorphine hydrochloride

GABRR2 CYP2D7 CYP2D6 TSPOAP1 ACLY UGT1A5 RGS9 SORT1 UGT1A4 UGT1A3 SYN1 PLCB3 CMKLR1

7.85e-0548117213CID000004253
Drugethoxyresorufin

DOCK3 CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

8.49e-05951726CID000003294
DrugN-OH-DABZ

UGT1A5 UGT1A4 UGT1A3

8.87e-05121723CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A5 UGT1A4 UGT1A3

8.87e-05121723CID000088735
Drug2,4,6-TCB

UGT1A5 UGT1A4 UGT1A3

8.87e-05121723CID000037247
Drugnonanoyl-N-methylglucamide

UGT1A5 UGT1A4 UGT1A3

8.87e-05121723CID000160090
DrugD02861

CYP2D7 CYP2D6 ACTG1

8.87e-05121723CID011954281
Drug7,7,7-triphenylheptanoic acid

UGT1A5 UGT1A4 UGT1A3

8.87e-05121723CID000276709
Druganiline

DOCK3 CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3 SORD

1.05e-041421727CID000006115
Drugglycerophosphoinositol

ACTB ACTG1 GDE1 GDPD5 ACSBG1

1.06e-04621725CID000167572
Drug6-methylsalicylic acid

ASZ1 UGT1A5 UGT1A4 UGT1A3

1.08e-04331724CID000011279
Druggeniposide

NOX5 UGT1A5 UGT1A4 UGT1A3

1.08e-04331724CID000107848
Drug5-azido-UDP-glucuronic acid

UGT1A5 UGT1A4 UGT1A3

1.15e-04131723CID003081279
Drugcotinine-N-glucuronide

UGT1A5 UGT1A4 UGT1A3

1.15e-04131723CID000000411
Drugestragole

UGT1A5 UGT1A4 UGT1A3 MTOR

1.22e-04341724CID000008815
DrugABT-538

CYP2D7 CYP2D6 UGT1A5 ACTG1 REL UGT1A4 UGT1A3

1.36e-041481727CID000005076
Drugammonia

CYP2D7 CYP2D6 UGT1A5 ACTB ACTG1 SLC26A9 TGM6 SLC4A3 UGT1A4 UGT1A3 PKD1 GAPDHS PNP

1.38e-0450917213CID000000222
Drugmexiletine

CYP2D7 CYP2D6 ANK2 FAT1 VCL

1.43e-04661725CID000004178
Drugpropranolol glucuronide

UGT1A5 UGT1A4 UGT1A3

1.45e-04141723CID000119515
DrugPCB-61

UGT1A5 UGT1A4 UGT1A3

1.45e-04141723CID000036401
DrugAC1L9DGV

FLNA UGT1A5 UGT1A4 UGT1A3

1.53e-04361724CID000417381
Drug4-(dimethylamino)benzoic acid

F8 OPA1

1.69e-0431722CID000012092
Drug2,4,6-trimethylbenzaldoxime

CYP2D7 CYP2D6

1.69e-0431722CID000283782
DrugO-demethyl encainide

CYP2D7 CYP2D6

1.69e-0431722CID000054736
Drugchlorpromazine N-oxide

CYP2D7 CYP2D6

1.69e-0431722CID000443037
Drugacotiamide

UGT1A5 UGT1A4 UGT1A3 VCL

1.71e-04371724CID005282338
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A5 UGT1A4 UGT1A3

1.80e-04151723CID000040469
Drugafloqualone

UGT1A5 UGT1A4 UGT1A3

1.80e-04151723CID000002040
Drugnaphthyl sulphate

UGT1A5 UGT1A4 UGT1A3

1.80e-04151723CID000114775
Drugcoumarin-3-carboxylic acid

UGT1A5 UGT1A4 UGT1A3

1.80e-04151723CID000010752
Drugsulforaphane nitrile

UGT1A5 UGT1A4 UGT1A3

1.80e-04151723CID000543743
Drugtrifluoperazine

NOX5 UGT1A5 ACTB ACTG1 UGT1A4 UGT1A3 SYN1 MYO15A ATP4A VCL

1.86e-0432417210CID000005566
Drugnitrosamine

CYP2D7 CYP2D6 UGT1A5 UGT1A4 UGT1A3

1.89e-04701725CID000037183
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A4 UGT1A3 RASAL2

2.65e-06181644EFO_0801382
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0800692
DiseaseX-24849 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A4 UGT1A3

9.25e-0681643EFO_0800766
DiseaseX-11442 measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0801036
DiseaseX-11880 measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A4 UGT1A3

1.38e-0591643EFO_0004570, GO_0009410
Diseaseurate measurement, spine bone mineral density

UGT1A5 UGT1A4 UGT1A3 SLC27A5 SORD

1.80e-05581645EFO_0004531, EFO_0007701
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A4 UGT1A3

1.97e-05101643EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A4 UGT1A3

1.97e-05101643EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A4 UGT1A3

1.97e-05101643EFO_0802185
DiseaseX-23974 measurement

UGT1A5 UGT1A4 UGT1A3

1.97e-05101643EFO_0800867
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A4 UGT1A3

2.69e-05111643EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A4 UGT1A3

2.69e-05111643EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

2.69e-05111643EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A5 UGT1A4 UGT1A3

2.69e-05111643EFO_0010219
DiseaseBaraitser-Winter syndrome

ACTB ACTG1

3.07e-0521642cv:C1853623
DiseaseIris Coloboma with Ptosis, Hypertelorism, and Mental Retardation

ACTB ACTG1

3.07e-0521642C1855722
DiseaseFryns-Aftimos Syndrome

ACTB ACTG1

3.07e-0521642C1853623
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A4 UGT1A3

3.57e-05121643EFO_0800079
Diseasebiliverdin measurement

UGT1A5 UGT1A4 UGT1A3

3.57e-05121643EFO_0021033
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A4 UGT1A3

4.63e-05131643EFO_0802007
DiseaseNonsyndromic genetic hearing loss

ACTG1 CDH23 OTOF PTPRQ MYO15A

6.70e-05761645cv:C5680182
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKD1 PKHD1

8.95e-05161643DOID:0110861 (implicated_via_orthology)
Diseasehormone measurement

UGT1A5 RYR2 UGT1A4 UGT1A3 SLC27A5

1.08e-04841645EFO_0004730
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A4 UGT1A3

1.08e-04171643EFO_0004611, EFO_0007800
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

MTOR PKD1

1.83e-0441642DOID:898 (is_implicated_in)
Diseasesolanidine measurement

CYP2D7 CYP2D6

1.83e-0441642EFO_0800966
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

CDH23 OTOF PTPRQ MYO15A

1.88e-04511644cv:CN043650
Diseasetissue factor measurement

UGT1A5 UGT1A4 UGT1A3

2.08e-04211643EFO_0010623
Diseaselissencephaly (is_implicated_in)

POMT1 PAFAH1B1

3.04e-0451642DOID:0050453 (is_implicated_in)
DiseaseFamilial Glucocorticoid Deficiency Type 1

MC2R TXNRD2

3.04e-0451642C4049650
DiseaseArsenic Induced Polyneuropathy

AKAP9 PTX3 TRAPPC10 PNP

3.99e-04621644C0751852
DiseaseArsenic Encephalopathy

AKAP9 PTX3 TRAPPC10 PNP

3.99e-04621644C0751851
DiseaseArsenic Poisoning

AKAP9 PTX3 TRAPPC10 PNP

3.99e-04621644C0311375
DiseaseArsenic Poisoning, Inorganic

AKAP9 PTX3 TRAPPC10 PNP

3.99e-04621644C0274861
DiseaseNervous System, Organic Arsenic Poisoning

AKAP9 PTX3 TRAPPC10 PNP

3.99e-04621644C0274862
DiseaseSchizophrenia

CYP2D6 ACTB RGS9 ADNP IL18R1 OPA1 UGT1A3 SLC26A7 MTOR HHAT PAFAH1B1 SYN1 SEPTIN11 MDGA1

4.37e-0488316414C0036341
Diseasepancreatic carcinoma

RNF149 SEC11C DOK2 SMC2 MED24 DDX54

4.41e-041741646EFO_0002618
Diseaseneuropathy (implicated_via_orthology)

MED24 SORD

4.54e-0461642DOID:870 (implicated_via_orthology)
Diseasexanthurenate measurement

UGT1A5 UGT1A4 UGT1A3

5.54e-04291643EFO_0010551
Diseasesugar consumption measurement

IGSF11 HHAT PKHD1 IGSF9B VPS13B

5.68e-041201645EFO_0010158
Diseaseresponse to dolutegravir

UGT1A5 UGT1A4 UGT1A3

6.13e-04301643EFO_0600017
DiseaseUveoretinal Coloboma

ACTB ACTG1

6.33e-0471642C4554007
DiseaseMoyamoya disease (implicated_via_orthology)

ACTB ACTG1

8.41e-0481642DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTB ACTG1

8.41e-0481642DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTB ACTG1

8.41e-0481642DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTB ACTG1

8.41e-0481642DOID:14004 (implicated_via_orthology)
DiseaseCongenital ocular coloboma (disorder)

ACTB ACTG1

1.08e-0391642C0009363
Diseasecataract (implicated_via_orthology)

PANK4 VPS13B SORD

1.23e-03381643DOID:83 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTB ACTG1

1.34e-03101642DOID:10486 (implicated_via_orthology)
DiseaseCongenital neurologic anomalies

ACTB ACTG1

1.34e-03101642C0497552
DiseaseCranioschisis

ACTB ACTG1

1.34e-03101642C0265541
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTB ACTG1

1.34e-03101642DOID:13832 (implicated_via_orthology)
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 RYR2

1.34e-03101642C1631597
DiseaseHereditary hearing loss and deafness

ACTG1 CDH23 OTOF PTPRQ MYO15A

1.37e-031461645cv:C0236038
Diseasecholelithiasis

UGT1A5 UGT1A4 UGT1A3 VPS13B

1.49e-03881644EFO_0004799
Diseasepregnenetriol sulfate measurement

UGT1A5 UGT1A4

1.63e-03111642EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A5 UGT1A4

1.63e-03111642EFO_0600039
Diseasehearing impairment

ACTG1 CDH23 OTOF MYO15A

2.21e-03981644C1384666
Diseasecircadian rhythm

HIKESHI SEC11C AKAP9 PLCL1 MTRF1L

2.22e-031631645EFO_0004354
DiseaseIGFBP-1 measurement

IGSF11 TGFBRAP1

2.30e-03131642EFO_0005118
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 PTPRQ

2.30e-03131642C1846647
Diseasepregnenetriol disulfate measurement

UGT1A5 UGT1A4

2.30e-03131642EFO_0800587
DiseaseRomano-Ward Syndrome

ANK2 AKAP9

3.50e-03161642C0035828
Diseaseidiopathic scoliosis (implicated_via_orthology)

MBTPS1 KATNB1

3.50e-03161642DOID:0060250 (implicated_via_orthology)
Diseasechronotype measurement

DOCK3 RGSL1 ANK2 SEC11C KCNT2 PAFAH1B1 PKHD1 PLCL1 CFAP61 MDGA1 MTRF1L ADGRA3

3.94e-0388216412EFO_0008328
DiseaseDystonia, Limb

CYP2D6 ACTB

3.95e-03171642C0751093
DiseaseDystonia, Diurnal

CYP2D6 ACTB

3.95e-03171642C0393610
DiseaseX-21441 measurement

UGT1A5 UGT1A4

3.95e-03171642EFO_0800814
Diseasebacteriemia

DOCK3 SH3RF2

3.95e-03171642EFO_0003033
Diseasemetabolite measurement

CYP2D7 CYP2D6 UGT1A5 MC2R UGT1A4 UGT1A3 L3HYPDH MDGA1 PNP

4.24e-035601649EFO_0004725
DiseaseDystonia, Paroxysmal

CYP2D6 ACTB

4.43e-03181642C0393588
Diseaseparahippocampal gyrus volume measurement

TFAP2D SORD

4.43e-03181642EFO_0010318
DiseasePost-Traumatic Osteoporosis

ACTG1 VCL PNP

4.79e-03611643C0751406
DiseaseOsteoporosis, Senile

ACTG1 VCL PNP

4.79e-03611643C0029459
DiseaseOsteoporosis, Age-Related

ACTG1 VCL PNP

4.79e-03611643C0001787
DiseaseOsteoporosis

ACTG1 VCL PNP

5.24e-03631643C0029456

Protein segments in the cluster

PeptideGeneStartEntry
HGIVVFSLGSMVSEI

UGT1A3

301

P35503
MEGESSRFEIHTPVS

TTF1

1

Q15361
VTAMIGHTNVVVPRS

ADNP

251

Q9H2P0
FPTIDHVVEAGFMTR

BEST2

151

Q8NFU1
HVNALTVMRTAIAPG

SLC4A3

1056

P48751
GSPRLFTSVMAVHRA

BBS5

116

Q8N3I7
TVIPESTIMRTLHSG

AKAP9

76

Q99996
MSVLTSPRGKVEVVH

CFAP61

1

Q8NHU2
VTQIVMTDAGRPHSE

CNTNAP3

761

Q9BZ76
FLMNEVVHTSPTIGS

ARL5B

36

Q96KC2
VTHMFSLPVNGSSVV

ADGRG4

1011

Q8IZF6
FDKTGTITHGVPRVM

ATP7B

1026

P35670
MTPSHRQVVFEGDSL

ADGRA3

246

Q8IWK6
IVMDSGDGVTHTVPI

ACTB

151

P60709
IVMDSGDGVTHTVPI

ACTG1

151

P63261
VPQMSSTGTVHITVI

FAT4

3591

Q6V0I7
LVFEVTRAHVTPMDQ

APCDD1L

351

Q8NCL9
DTIVGMLHNRSETPT

CDT1

201

Q9H211
AAVVLHSPLTSGMRV

ABHD17A

206

Q96GS6
GSEMTTVPLLHAAIR

SORD

276

Q00796
RSHSATAVDFLPVMV

BCO2

11

Q9BYV7
RVTMLTAPLGFSVHL

DCLRE1B

421

Q9H816
FHVDMDSGLVTTQRP

CDH23

2556

Q9H251
TPIMYAARDGHTQVV

ASZ1

151

Q8WWH4
MSTTFPGLVHDAEIR

TFAP2D

1

Q7Z6R9
EPVFHVMGFSVTGRV

NOMO3

321

P69849
PLSRETHIFMQVADT

PCDHGA7

431

Q9Y5G6
STEVHMVRPGYSHRV

RUBCNL

131

Q9H714
VVRTMSPHGESADSI

TSPOAP1

1056

O95153
VLVTSVPHAMTGSDV

RGS9

41

O75916
DYRTRVSGVTPQHMV

ISG20

51

Q96AZ6
VTRVIFHPVFSVMVS

PAFAH1B1

111

P43034
LMPVVAGAVFTLTAH

NUP205

1331

Q92621
RFPGVMENLTISAAH

NOX5

196

Q96PH1
EPGSQMVEASLSVRH

KLK4

91

Q9Y5K2
ATGSIPITVRHIESM

MCM2

756

P49736
SPDVTNIRGETALHM

ANK2

456

Q01484
EPMLTVHQTVSDVRG

MDGA1

131

Q8NFP4
RTDMFAIHPTSGVIV

FAT1

191

Q14517
TVQVHDMGTPRLFAE

FAT1

1846

Q14517
HTIFVRAVDGGMPTL

FAT1

2356

Q14517
IVMDSGDGVTHTVPI

POTEF

851

A5A3E0
EPVFHVMGFSVTGRV

NOMO2

321

Q5JPE7
LSGVVPTMHFTIAEG

ADIPOR1

276

Q96A54
SAVTVGPHKEFAVTM

DOK2

141

O60496
HPVVITSFEIAMRDR

HELLS

326

Q9NRZ9
DIPGHVFTRGMIIAV

IL18R1

321

Q13478
SVQHATVIPETMAGT

HIPK2

731

Q9H2X6
ASGHSVPVVTVVRAM

HTATIP2

196

Q9BUP3
GHVMITVASPAETES

MBTPS1

581

Q14703
MGIPSVRREVHSYLT

MGAT4B

146

Q9UQ53
TGVDHMASPLVQTSR

FAM149A

641

A5PLN7
THVTEMQDSFVRPEG

ITPRID1

571

Q6ZRS4
DVTAHAGTLPSRMTV

GTPBP6

331

O43824
MTHLAAAPGTQVSRE

MYO15A

2621

Q9UKN7
PIIRVMTFVGHASGK

FANCM

501

Q8IYD8
IMSLTGHTSPVESVR

KATNB1

56

Q9BVA0
FVPGERSVIIMNHRT

LCLAT1

111

Q6UWP7
IATPGRLVHVAVEMS

DDX54

221

Q8TDD1
VVDVREGPAFHPSTM

DSG4

376

Q86SJ6
HATVPEMSNVGTSVI

CDH24

156

Q86UP0
HPQVGESVSVVTVMR

HMGXB3

256

Q12766
SEMFAIHPTSGVVTV

FAT2

191

Q9NYQ8
THFVALMVTEPGLQA

LENG9

321

Q96B70
IHVFGIVESGVLVSM

OR51H1

106

Q8NH63
LIFFVPVIGVSMVHR

OR51L1

251

Q8NGJ5
EPVFHVMGFSVTGRV

NOMO1

321

Q15155
ITGHITGMASAFRTV

SLC25A28

301

Q96A46
EHASVMLDVPIRLTG

RASAL2

721

Q9UJF2
TDVSQDPRHMVLVRG

MED25

211

Q71SY5
TLPGRHTVEMLVISF

METTL23

171

Q86XA0
APFLHVGAVAAVTML

GDPD5

161

Q8WTR4
VIGMGTTPEVHSIFL

F8

276

P00451
PVHSIIASMGTVAID

KCNT2

586

Q6UVM3
MDVVSVHFQPLDRVS

PGAP6

361

Q9HCN3
SAHVTVVILFFGPLM

OR4F15

241

Q8NGB8
TFPRVIMQEVEHALS

PARM1

241

Q6UWI2
RMPFLVETLHASSVE

HMCN1

5051

Q96RW7
RRLVPFTEHMISVSA

PTPRQ

576

Q9UMZ3
IRGHPVTMRTITYSI

PANK4

326

Q9NVE7
TPGVAMVLLHTTISF

HHAT

111

Q5VTY9
ITMGSVRPSVEQFHK

NPC1L1

996

Q9UHC9
IVMDSGDGVTHTVPI

POTEE

851

Q6S8J3
ILVFRSGPHDQIMSS

POMT1

286

Q9Y6A1
SIVTDLVSQMDPHGR

OPA1

446

O60313
FITHGFTMTTEVPLR

PLCB3

376

Q01970
TTMILDHVFPDTGVS

DPYSL4

101

O14531
ESINHVVVFMLGTIP

HIKESHI

31

Q53FT3
GIPVLMHDNTVDRTT

GDE1

106

Q9NZC3
ISHATLERIGAVPVM

IGSF11

406

Q5DX21
FVRGTLGSMPSTVHI

DOCK3

811

Q8IZD9
RFVPAEMGTHTVSVK

FLNA

2201

P21333
FGDIVPLGVTHMTSR

CYP2D6

366

P10635
PLGVTHMTSRDIEVQ

CYP2D6

371

P10635
HMTSRDIEVQGFRIP

CYP2D6

376

P10635
VTVTVCRSFIPDQHM

ATG9A

416

Q7Z3C6
VDATAVTDVPFQRMH

TMEM132E-DT

36

A2RUQ5
AATVLPMVRSEHVTV

CRYBG2

401

Q8N1P7
VVEGNHMVYRISAPT

CYTH2

346

Q99418
LTAAHVVEGNREPTM

C1S

471

P09871
VNTLREVEPTSHMGV

ACSBG1

361

Q96GR2
VSTPEFIHAAMRPDV

ELF2

126

Q15723
FIHAAMRPDVITETV

ELF2

131

Q15723
DVMVNTDPVHGLLTR

KANK4

411

Q5T7N3
VLAGDHMQVTPRLFS

HELZ2

691

Q9BYK8
PMVHSTFLASLRAEG

CERCAM

211

Q5T4B2
IHERFGIVEGLMTTV

GAPDHS

236

O14556
LAEHMPVLVSGIIFS

CAND2

471

O75155
SGHVTRLGLSMVEFP

DHX40

476

Q8IX18
GVSVHFRHVVPSIME

SLC22A14

406

Q9Y267
HVSSMRPNIFLGVSE

RYR2

651

Q92736
AVGMSTVPEVIVARH

PNP

216

P00491
GIRVIMVTGDHPITA

ATP4A

621

P20648
EALRTHPEMVFARTS

ATP4A

691

P20648
TTTDNIMLRVFPDGH

GABRR2

151

P28476
FPDGHVLYSMRITVT

GABRR2

161

P28476
SHSTGEVVVTMEPEV

OTOF

1261

Q9HC10
HVTMVFPDAGTFSIR

PKD1

1851

P98161
ATTVEMATGHIVPEG

PTX3

291

P26022
MAEFIGQTGTVHRIT

MIB2

286

Q96AX9
VFMHDNSPGRIVSIK

MTOR

1081

P42345
RDHIIEVVGSSMPLI

SYN1

381

P17600
LDRSVFHGAIMSVFP

RGSL1

956

A5PLK6
VLTTFHVPLVIMTFG

SORT1

126

Q99523
MEPRRITSAASVLFH

SRRM3

571

A6NNA2
LYVVEVRHGPSSVEM

SMYD4

726

Q8IYR2
IVVVLSGSMEPAFHR

SEC11C

61

Q9BY50
ATMSVHLPFAVVGST

SEPTIN11

226

Q9NVA2
HQMVPGTFAVISILV

SLC26A9

121

Q7LBE3
AIVHSTSDPIMTARG

NCKAP5

1786

O14513
QGRVHTSTMTVAILP

MTRF1L

211

Q9UGC7
GVTVPSTREVMSLHE

EPPK1

1901

P58107
FPTVHAVILLEGTMN

MED24

241

O75448
GMIVAEVVSARIHPE

TELO2

406

Q9Y4R8
IVMDSGDGVTHTVPI

POTEI

851

P0CG38
FHRMSIGLANTPEVS

PKHD1

2571

P08F94
ETVIMPVFGIATPFH

SUPT16H

536

Q9Y5B9
VRTRGTLEEMPTVQH

DUSP26

26

Q9BV47
SVVDMHTGGEPLRIV

L3HYPDH

21

Q96EM0
VSTAGRMHIFKPVSV

SSH1

161

Q8WYL5
PIHVFGTETHMTAIV

ACLY

401

P53396
TGITMVIFSHHVPTV

MC2R

161

Q01718
PVGYSRHMVVTVTRF

CMKLR1

211

Q99788
DIVPLGVTHMTSRDI

CYP2D7

386

A0A087X1C5
VPLRSFVGDIMEHVT

PLCL1

826

Q15111
VTMTIGVGTRHVQEF

RNF149

181

Q8NC42
MFATVAGISQRAPVH

TGFBRAP1

231

Q8WUH2
VEVIFHVSTRMPSDS

RALGAPA1

1876

Q6GYQ0
GVPDLVHVMRTLASE

PPM1A

326

P35813
PHFIRIQDAMEVTST

SLC27A5

626

Q9Y2P5
HAPGSVRVQVSMTTA

IGSF9B

511

Q9UPX0
RVVVETVHPGMLADA

SPATC1

556

Q76KD6
TVIFPSSHSFILIMG

TAS2R9

271

Q9NYW1
SSGHVTFTMDPIRDL

TRPM2

611

O94759
HPTVLVQRGHSSMFV

SPATA31D1

516

Q6ZQQ2
PHAMVRVSVNGAVVL

PFAS

986

O15067
FMSTHRIVTEGRVVT

THEMIS2

111

Q5TEJ8
ASVFGTMPLKVVEHR

EXT2

681

Q93063
MPVFHTRTIESILEP

VCL

1

P18206
SPRHEVTEMGQEVTL

TRBV12-3

26

P01733
HGIVVFSLGSMVSEI

UGT1A5

301

P35504
MEPTVADVHLVPRTT

TMPRSS9

1

Q7Z410
VAMHTVGFAETVRDL

SLC12A3

231

P55017
LFSHDAVVREMPTGV

REL

366

Q04864
MTRTVTLGGDVFDPH

SMC2

646

O95347
TFTVHMPEIALVRFL

PLCH1

796

Q4KWH8
MPAKTFAGVRVHVVD

ZNFX1

1171

Q9P2E3
SPRHEVTEMGQEVTL

TRBV12-4

26

A0A0B4J2E0
MRTVGIHPTCSEEVV

TXNRD2

491

Q9NNW7
PEVHMALDVVLVRGS

VPS13B

3866

Q7Z7G8
VIMTRLTESGHPSSD

ZNF215

251

Q9UL58
SGRHMVEISTPVLIS

SH3RF2

316

Q8TEC5
ARVTQTPRHKVTEMG

TRBV12-5

21

A0A1B0GX78
TRTPIVTLSGHMEAV

WDR12

246

Q9GZL7
GVISMPVAARATHRV

TRAPPC10

1131

P48553
ALFTETPHDMTARTG

VSTM2L

41

Q96N03
EPVISAMTTGAATHV

SLC26A7

176

Q8TE54
FTMETGPRASEALHT

TGM6

56

O95932
SDTIEMVRVAGHPNV

TMEM236

246

Q5W0B7
PSVRAAFIHVIGDFM

SLC30A2

166

Q9BRI3
HGIVVFSLGSMVSEI

UGT1A4

301

P22310
PVHQSVTMGETVSFL

WFIKKN2

216

Q8TEU8
ETTRIMRVSHTFPVV

KIAA0319

41

Q5VV43