Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	TPP2 RHBDD1 KLK10 KLK14 PRSS58 PRSS36 BMP1 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	2.71e-11	190	185	16	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	TPP2 RHBDD1 KLK10 KLK14 PRSS58 PRSS36 BMP1 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	9.85e-11	207	185	16	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	TPP2 RHBDD1 KLK10 KLK14 PRSS58 PRSS36 BMP1 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	1.41e-10	212	185	16	GO:0017171
GeneOntologyMolecularFunction	peptidase activity	NAPSA TPP2 RHBDD1 USP17L4 KLK10 USP17L2 USP17L1 KLK14 CPB2 PRSS58 PRSS36 ADGRG6 BMP1 CELA3B KLK4 CELA3A USP17L3 PRSS45P MST1L TPSG1 PRSS48 KLK1 ECE2 PROC USP17L8	1.99e-09	654	185	25	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	NAPSA TPP2 RHBDD1 KLK10 KLK14 PRSS58 PRSS36 ADGRG6 BMP1 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 ECE2 PROC	2.04e-08	430	185	19	GO:0004175
GeneOntologyMolecularFunction	complement receptor activity	FPR2 CR1 CR2	2.64e-04	14	185	3	GO:0004875
Domain	Peptidase_S1A	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	7.12e-11	113	181	13	IPR001314
Domain	TRYPSIN_DOM	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	8.91e-11	115	181	13	PS50240
Domain	Tryp_SPc	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	1.11e-10	117	181	13	SM00020
Domain	Trypsin_dom	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	1.70e-10	121	181	13	IPR001254
Domain	Trypsin	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	1.70e-10	121	181	13	PF00089
Domain	Peptidase_S1_PA	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P MST1L TPSG1 PRSS48 KLK1 PROC	2.10e-10	123	181	13	IPR009003
Domain	TRYPSIN_HIS	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P TPSG1 PRSS48 KLK1 PROC	3.38e-10	103	181	12	IPR018114
Domain	TRYPSIN_SER	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P TPSG1 PRSS48 KLK1 PROC	4.74e-10	106	181	12	PS00135
Domain	TRYPSIN_HIS	KLK10 KLK14 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P TPSG1 PRSS48 KLK1 PROC	5.30e-10	107	181	12	PS00134
Domain	CUB	LRP12 ADGRB3 CSMD3 ADGRG6 BMP1 NETO2 SEZ6L	7.56e-07	53	181	7	PS01180
Domain	CUB_dom	LRP12 ADGRB3 CSMD3 ADGRG6 BMP1 NETO2 SEZ6L	1.26e-06	57	181	7	IPR000859
Domain	TRYPSIN_SER	KLK14 PRSS36 CELA3B KLK4 CELA3A PRSS48 KLK1 PROC	2.62e-06	90	181	8	IPR033116
Domain	CUB	LRP12 CSMD3 ADGRG6 BMP1 NETO2 SEZ6L	7.54e-06	49	181	6	PF00431
Domain	CUB	LRP12 CSMD3 ADGRG6 BMP1 NETO2 SEZ6L	8.50e-06	50	181	6	SM00042
Domain	-	LRP12 CSMD3 ADGRG6 BMP1 NETO2 SEZ6L	1.07e-05	52	181	6	2.60.120.290
Domain	GPCR_2_extracellular_dom	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	4.04e-05	40	181	5	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	4.04e-05	40	181	5	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	4.04e-05	40	181	5	PS50227
Domain	LisH	RANBP10 TBL1Y TBL1XR1	7.20e-05	9	181	3	PF08513
Domain	HormR	ADGRB3 CRHR1 CELSR1 CELSR2	9.20e-05	25	181	4	SM00008
Domain	Hyd_WA	TECPR2 TECPR1	9.34e-05	2	181	2	PF06462
Domain	7tm_2	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	1.20e-04	50	181	5	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	1.20e-04	50	181	5	PS00650
Domain	GAIN_dom_N	ADGRB3 CELSR1 CELSR2	1.39e-04	11	181	3	IPR032471
Domain	GAIN	ADGRB3 CELSR1 CELSR2	1.39e-04	11	181	3	PF16489
Domain	HRM	ADGRB3 CRHR1 CELSR1 CELSR2	1.46e-04	28	181	4	PF02793
Domain	TECPR	TECPR2 TECPR1	2.78e-04	3	181	2	SM00706
Domain	Radial_spoke	RSPH4A RSPH6A	2.78e-04	3	181	2	PF04712
Domain	Beta-propeller_rpt_TECPR	TECPR2 TECPR1	2.78e-04	3	181	2	IPR006624
Domain	Radial_spoke	RSPH4A RSPH6A	2.78e-04	3	181	2	IPR006802
Domain	GPCR_2_secretin-like	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	2.87e-04	60	181	5	IPR000832
Domain	GPCR_2-like	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	2.87e-04	60	181	5	IPR017981
Domain	WD40	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	2.95e-04	268	181	10	SM00320
Domain	G_PROTEIN_RECEP_F2_4	ADGRB3 CRHR1 ADGRG6 CELSR1 CELSR2	3.10e-04	61	181	5	PS50261
Domain	GPS	ADGRB3 ADGRG6 CELSR1 CELSR2	3.15e-04	34	181	4	SM00303
Domain	WD40_repeat	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	3.31e-04	272	181	10	IPR001680
Domain	GPS	ADGRB3 ADGRG6 CELSR1 CELSR2	3.53e-04	35	181	4	PF01825
Domain	WD_REPEATS_1	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	3.94e-04	278	181	10	PS00678
Domain	GPS	ADGRB3 ADGRG6 CELSR1 CELSR2	3.94e-04	36	181	4	PS50221
Domain	WD_REPEATS_2	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	4.05e-04	279	181	10	PS50082
Domain	WD_REPEATS_REGION	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	4.05e-04	279	181	10	PS50294
Domain	GPS	ADGRB3 ADGRG6 CELSR1 CELSR2	4.39e-04	37	181	4	IPR000203
Domain	CaMKII_AD	CAMK2B CAMK2G	5.53e-04	4	181	2	PF08332
Domain	Ca/CaM-dep_prot_kinase-assoc	CAMK2B CAMK2G	5.53e-04	4	181	2	IPR013543
Domain	UCH	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	6.28e-04	71	181	5	PF00443
Domain	USP_2	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	6.28e-04	71	181	5	PS00973
Domain	WD40_repeat_dom	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	6.58e-04	297	181	10	IPR017986
Domain	USP_3	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	6.69e-04	72	181	5	PS50235
Domain	USP_dom	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	6.69e-04	72	181	5	IPR028889
Domain	Peptidase_C19_UCH	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	6.69e-04	72	181	5	IPR001394
Domain	WD40	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 WDR62	9.78e-04	259	181	9	PF00400
Domain	-	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	1.56e-03	333	181	10	2.130.10.10
Domain	Sushi	CR1 CR2 CSMD3 SEZ6L	1.61e-03	52	181	4	PF00084
Domain	WD40/YVTN_repeat-like_dom	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 TECPR2 WDR62	1.63e-03	335	181	10	IPR015943
Domain	CCP	CR1 CR2 CSMD3 SEZ6L	1.85e-03	54	181	4	SM00032
Domain	SUSHI	CR1 CR2 CSMD3 SEZ6L	2.12e-03	56	181	4	PS50923
Domain	Sushi_SCR_CCP_dom	CR1 CR2 CSMD3 SEZ6L	2.26e-03	57	181	4	IPR000436
Domain	LisH	RANBP10 TBL1Y TBL1XR1	2.45e-03	28	181	3	IPR006594
Domain	LisH	RANBP10 TBL1Y TBL1XR1	2.45e-03	28	181	3	SM00667
Domain	LISH	RANBP10 TBL1Y TBL1XR1	2.45e-03	28	181	3	PS50896
Pathway	REACTOME_RAS_PROCESSING	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	5.61e-05	45	130	5	MM15671
Pathway	KEGG_WNT_SIGNALING_PATHWAY	TBL1Y CAMK2B CAMK2G WNT9A DVL1 TBL1XR1 WNT10A SMAD3	7.76e-05	151	130	8	M19428
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.11e-09	10	189	5	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	3.45e-09	12	189	5	24695638
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L4 USP17L2 USP17L1 TLR9 USP17L3 USP17L8	3.87e-09	25	189	6	21115691
Pubmed	Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.	OR14J1 OR2J3 OR2J2 OR2H1 OR2H2	5.58e-09	13	189	5	14506126
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.65e-09	14	189	5	11793228
Pubmed	Human and mouse proteases: a comparative genomic approach.	RHBDD1 USP17L4 USP17L2 USP17L1 USP17L3 PRSS45P PRSS48 USP17L8	1.50e-08	81	189	8	12838346
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	4.91e-08	19	189	5	28067227
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	8.52e-08	21	189	5	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-07	22	189	5	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.76e-07	24	189	5	8995226
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	2.69e-07	26	189	5	35816173
Pubmed	Complex transcription and splicing of odorant receptor genes.	OR2J3 OR2J2 OR2H1 OR2H2	2.71e-07	11	189	4	12637542
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	4.80e-07	29	189	5	32527007
Pubmed	Human tissue kallikreins: physiologic roles and applications in cancer.	KLK10 KLK14 KLK4 KLK1	5.81e-07	13	189	4	15192120
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	9.43e-07	33	189	5	20228807
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	20403174
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	11941478
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	20388806
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	20368735
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.10e-06	34	189	5	21448158
Pubmed	Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.	KLK10 KLK14 KLK4 KLK1	1.10e-06	15	189	4	15203212
Pubmed	Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005.	KLK10 KLK14 KLK4 KLK1	1.10e-06	15	189	4	16800723
Pubmed	A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.	KLK10 KLK14 KLK4 KLK1	1.10e-06	15	189	4	16800724
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.28e-06	35	189	5	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.28e-06	35	189	5	21239494
Pubmed	Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer.	KLK10 KLK14 KLK4 KLK1	1.46e-06	16	189	4	20424135
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.48e-06	36	189	5	20147298
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.70e-06	37	189	5	20228808
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RANBP10 SP2 TCAF1 THSD7A RNF213 ARHGAP39 CUL7 CLSTN1 ABLIM3 FCHO1 TULP4 POP1 HELZ2	3.43e-06	493	189	13	15368895
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	WNT9A DVL1 CELSR1 CELSR2 WNT10A	5.73e-06	47	189	5	33141892
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	7.81e-06	50	189	5	31806660
Pubmed	Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.	KLK10 KLK14 KLK4 KLK1	8.24e-06	24	189	4	15331780
Pubmed	Organization and evolution of the glandular kallikrein locus in Mus musculus.	KLK10 KLK14 KLK1	1.84e-05	10	189	3	12437987
Pubmed	Association between kallikrein-related peptidases (KLKs) and macroscopic indicators of semen analysis: their relation to sperm motility.	KLK10 KLK14 KLK1	1.84e-05	10	189	3	19558318
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	ILK CAMK2B CAMK2G CYP26A1 SSTR4 TBL1XR1 PTPRJ NPRL3 TRAPPC10	2.21e-05	276	189	9	28319085
Pubmed	Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.	CR1 CR2	2.94e-05	2	189	2	14635039
Pubmed	Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.	CELA3B CELA3A	2.94e-05	2	189	2	27999401
Pubmed	The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions.	KLK4 KLK1	2.94e-05	2	189	2	11258672
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	2.94e-05	2	189	2	23292348
Pubmed	The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.	CR1 CR2	2.94e-05	2	189	2	11981823
Pubmed	A role for CaMKII in T cell memory.	CAMK2B CAMK2G	2.94e-05	2	189	2	10693762
Pubmed	Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells.	CPB2 PROC	2.94e-05	2	189	2	26663133
Pubmed	Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.	CR1 CR2	2.94e-05	2	189	2	1708808
Pubmed	Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes.	CELA3B CELA3A	2.94e-05	2	189	2	2460440
Pubmed	The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.	CAMK2B CAMK2G	2.94e-05	2	189	2	15294044
Pubmed	MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy.	TLR9 MTMR3	2.94e-05	2	189	2	37414396
Pubmed	Comparative functional evolution of human and mouse CR1 and CR2.	CR1 CR2	2.94e-05	2	189	2	18713965
Pubmed	Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung.	NAPSA SFTPB	2.94e-05	2	189	2	13129928
Pubmed	Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor.	TPP2 RYR3	2.94e-05	2	189	2	23818952
Pubmed	Repression of Smad3 activity by histone demethylase SMCX/JARID1C.	KDM5C SMAD3	2.94e-05	2	189	2	18078810
Pubmed	Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.	CR1 CR2	2.94e-05	2	189	2	37833411
Pubmed	[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].	CR1 CR2	2.94e-05	2	189	2	26189291
Pubmed	Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.	CR1 CR2	2.94e-05	2	189	2	23440418
Pubmed	NETO2 promotes melanoma progression via activation of the Ca2+/CaMKII signaling pathway.	CAMK2G NETO2	2.94e-05	2	189	2	36738427
Pubmed	Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning.	CELA3B CELA3A	2.94e-05	2	189	2	2826474
Pubmed	Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.	SLC22A11 SLC22A9	2.94e-05	2	189	2	10660625
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB3 ADGRG6 CELSR1 CELSR2	3.06e-05	33	189	4	25713288
Pubmed	Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters.	TSPEAR GRIK1 UBASH3A LINC00315	3.45e-05	34	189	4	20494980
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 CRYBG2 DVL1 OBSCN FBRSL1 GEMIN5 ICE1 LYST CELSR1 ARAP3 CELSR2 TULP4 IL17RE HELZ2 MTMR3 NPRL3 MFSD5 WNK2	3.68e-05	1105	189	18	35748872
Pubmed	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	FBRSL1 OR14J1 OR2J3 OR2J2 OR2H1 MPIG6B OR2H2	5.13e-05	175	189	7	19851445
Pubmed	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.	KLK10 KLK4 KLK1	5.50e-05	14	189	3	11054574
Pubmed	Differences in Kallikrein-related peptidase mRNA sequences and KLK6 enzyme activity between mouse strains.	KLK10 KLK14 KLK1	5.50e-05	14	189	3	25666037
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SART3 RANBP10 THSD7A TTC28 CUL7 CLSTN1	8.12e-05	130	189	6	12421765
Pubmed	Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis.	TSPEAR WNT10A	8.78e-05	3	189	2	30046887
Pubmed	Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta.	SLC22A11 SLC22A9	8.78e-05	3	189	2	18501590
Pubmed	Genetic Variation, Stress, and Physiological Stress Response in Adults With Food Allergy or Celiac Disease.	CRHR1 OXTR	8.78e-05	3	189	2	36280595
Pubmed	Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor.	KLK10 KLK14	8.78e-05	3	189	2	19383315
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	8.78e-05	3	189	2	11677057
Pubmed	Processing of pulmonary surfactant protein B by napsin and cathepsin H.	NAPSA SFTPB	8.78e-05	3	189	2	14766755
Pubmed	Calcium/calmodulin-dependent protein kinase II and calmodulin: regulators of the meiotic spindle in mouse eggs.	CAMK2B CAMK2G	8.78e-05	3	189	2	9882483
Pubmed	Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.	CR1 CR2	8.78e-05	3	189	2	7690834
Pubmed	Identification of novel human tumor cell-specific CaMK-II variants.	CAMK2B CAMK2G	8.78e-05	3	189	2	9060999
Pubmed	Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.	CAMK2B CAMK2G	8.78e-05	3	189	2	10819240
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CR1 CR2	8.78e-05	3	189	2	3782802
Pubmed	Surfactant Expression Defines an Inflamed Subtype of Lung Adenocarcinoma Brain Metastases that Correlates with Prolonged Survival.	NAPSA SFTPB	8.78e-05	3	189	2	31953311
Pubmed	Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.	CAMK2B CAMK2G	8.78e-05	3	189	2	20844140
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR2	8.78e-05	3	189	2	2528587
Pubmed	Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.	TLR9 CR2	8.78e-05	3	189	2	29515028
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR2	8.78e-05	3	189	2	7528766
Pubmed	KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cbeta3 on 537-Ser.	CAMK2B CAMK2G	8.78e-05	3	189	2	11325525
Pubmed	Clock gene modulates roles of OXTR and AVPR1b genes in prosociality.	CLOCK OXTR	8.78e-05	3	189	2	25309987
Pubmed	CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid beta 1-42 peptide by up-regulating the expression of the G-protein- coupled receptor mFPR2.	FPR2 TLR9	8.78e-05	3	189	2	16219804
Pubmed	Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1.	GRIK1 NETO2	8.78e-05	3	189	2	26720915
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR2	8.78e-05	3	189	2	2139460
Pubmed	The complete human olfactory subgenome.	OR2J3 OR2J2	8.78e-05	3	189	2	11337468
Pubmed	DNA sequence and analysis of human chromosome 8.	USP17L4 USP17L1 USP17L3 USP17L8	1.36e-04	48	189	4	16421571
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SART3 KDM5C ADGRB3 FBRSL1 G2E3 ICE1 RGP1 CLOCK TECPR2 FAM149B1 WNK2	1.64e-04	529	189	11	14621295
Pubmed	The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors.	GRIK1 NETO2	1.75e-04	4	189	2	26277340
Cytoband	22q12.1	TTC28 MYO18B SEZ6L	3.12e-04	32	189	3	22q12.1
Cytoband	8p23.1	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	4.62e-04	154	189	5	8p23.1
Cytoband	1p36.12	SH2D5 CELA3B CELA3A	5.63e-04	39	189	3	1p36.12
GeneFamily	Kallikreins	KLK10 KLK14 KLK4 KLK1	2.66e-06	16	115	4	616
GeneFamily	Proteases, serine	PRSS58 PRSS36 KLK4 PRSS45P TPSG1 PRSS48	2.94e-06	63	115	6	738
GeneFamily	WD repeat domain containing	WDR7 TBL1Y FBXW4 GEMIN5 WDR54 TBL1XR1 LYST TULP4 WDR62	4.53e-05	262	115	9	362
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.20e-04	3	115	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.20e-04	3	115	2	1189
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CR1 CR2 CSMD3 SEZ6L	4.73e-04	57	115	4	1179
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP1 BMP15	2.12e-03	11	115	2	455
GeneFamily	PHD finger proteins	KDM5C G2E3 PHF8 BRD1	2.61e-03	90	115	4	88
GeneFamily	Adenosine receptors\|V-set domain containing	NPHS1 TIMD4 MXRA8 CD226 TREM2	3.88e-03	163	115	5	590
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	THSD7A CAMK2B WNT9A GABBR2 CLSTN1 ABLIM3 WNT10A DCLK2 TECPR1	6.38e-08	176	188	9	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA CRISPLD2 SFTPB SGCA MXRA8 CPB2 MRPL14 C11orf96 CHRDL1	1.60e-07	196	188	9	988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	RHBDD1 MXRA8 FBRSL1 GEMIN5 ARAP3 NPRL3 LIPT2 GSG1L	8.19e-07	175	188	8	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDD1 KDM5C ABLIM3 SLC4A1AP NQO1 DCLK2 KLHL8 SMOX	1.46e-06	189	188	8	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIWIL4 GJD4 CELSR2 NETO2 IL17RE TEX26 PROC	2.34e-06	141	188	7	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIWIL4 GJD4 CELSR2 NETO2 IL17RE TEX26 PROC	2.34e-06	141	188	7	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIWIL4 GJD4 CELSR2 NETO2 IL17RE TEX26 PROC	2.46e-06	142	188	7	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GABBR2 UBASH3A GALR2 CD226 WNT10A CARD11 PROC	3.69e-06	151	188	7	b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM178B TLR9 CR1 FCHO1 TBC1D8 WNT10A CARD11	3.86e-06	152	188	7	0c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA THSD7A SFTPB KLK14 NETO2 SMOX WNK2	7.17e-06	167	188	7	8fede587572d465cb63f7828141a574185bbb819
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP26A1 GALR2 GJD4 CILP2 NOTUM GSG1L BMP15	9.02e-06	173	188	7	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TIMD4 FBRSL1 TBC1D8 SLC4A1AP DCLRE1A TMEM39A PAN3	1.05e-05	177	188	7	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 TSPEAR CR1 CDC14A RYR3	1.05e-05	177	188	7	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 TSPEAR CR1 CDC14A RYR3	1.09e-05	178	188	7	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NAPSA SFTPB PRSS36 BMP1 MRPL14 NANS TEX26	1.30e-05	183	188	7	5f2db95d44b7de68779de098892892af540fd431
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A GEMIN5 RYR3 EPG5 CELA3B NQO1 TMEM220	1.30e-05	183	188	7	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 TSPEAR CR1 CDC14A RYR3	1.39e-05	185	188	7	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 TSPEAR CR1 CDC14A RYR3	1.39e-05	185	188	7	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRISPLD2 WNT9A ADGRB3 RYR3 C11orf96 DCLK2 SMAD3	1.39e-05	185	188	7	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRISPLD2 SGCA WNT9A ADGRB3 RYR3 ADGRG6 GSG1L	1.55e-05	188	188	7	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A WDR54 DNAH7 TBC1D8 OXTR TEX26 NQO1	1.60e-05	189	188	7	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA KLK10 SFTPB KLK14 CPB2 MRPL14 C11orf96	1.71e-05	191	188	7	1c46f4eabc1fd790069d5d8b29580d3904e2ef41
ToppCell	18-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	CRISPLD2 SGCA NDST4 ABLIM3 NOTUM C11orf96 RPL3	1.71e-05	191	188	7	86ce98d2c90c196474b06869de888cf5d1eed196
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A WDR54 DNAH7 TBC1D8 OXTR TEX26 NQO1	1.71e-05	191	188	7	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SFTPB CPB2 B3GNT8 BMP1 MRPL14 C11orf96	1.96e-05	195	188	7	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SFTPB CPB2 B3GNT8 BMP1 MRPL14 C11orf96	1.96e-05	195	188	7	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAPSA SFTPB CPB2 B3GNT8 BMP1 MRPL14 C11orf96	1.96e-05	195	188	7	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	LAM-Epithelial-AT2\|LAM / Condition, Lineage and Cell class	NAPSA SFTPB CPB2 B3GNT8 BMP1 MRPL14 C11orf96	2.02e-05	196	188	7	9165041ef3d56b4d069497fee03dd1c6e273211d
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LYST DIPK2A ADGRG6 NANS NQO1 TMEM39A HMGCLL1	2.09e-05	197	188	7	ec92d60f802c9d4bdf9877bed5c0a91a5a5ed5d0
ToppCell	LAM-Epithelial-AT2\|Epithelial / Condition, Lineage and Cell class	NAPSA SFTPB CPB2 B3GNT8 BMP1 MRPL14 C11orf96	2.09e-05	197	188	7	27e6eb7bbc27e7635df1aae7c7d75f8a3f1b1cc2
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LYST DIPK2A ADGRG6 NANS NQO1 TMEM39A HMGCLL1	2.09e-05	197	188	7	7bec9c1bc8851064eb229324493b47a31201c83c
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRISPLD2 ILK SGCA RYR3 C11orf96 CHRDL1 GSG1L	2.23e-05	199	188	7	a207b4891881149d4c50721310690fd794157723
ToppCell	Influenza-Influenza_Severe-Myeloid-cDC\|Influenza_Severe / Disease, condition lineage and cell class	FAM178B HPDL RGS12 RYR3 IL17RE TMEM220 SEZ6L	2.30e-05	200	188	7	b8415a68ad6f4fea562236a1b0da0dc376d874fb
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CRISPLD2 WNT9A GJD4 ADGRG6 C11orf96 OR2H2	2.67e-05	138	188	6	8d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	THSD7A TSPEAR GRIK1 RGS12 RYR3 OXTR	4.11e-05	149	188	6	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CAMK2B MXRA8 CR1 CDC14A RYR3	5.90e-05	159	188	6	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CAMK2B MXRA8 CR1 CDC14A RYR3	5.90e-05	159	188	6	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CAMK2B MXRA8 CR1 CDC14A RYR3	5.90e-05	159	188	6	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA OBSCN SSTR4 SH2D5 TBC1D8 KLK1	6.11e-05	160	188	6	237430af14830b38e58da8a4224036e5c6b71c5b
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TLR9 CR1 FCHO1 TBC1D8 WNT10A CARD11	6.11e-05	160	188	6	dee756a2dc9725520d439e7273c489c2284015d8
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ALG1L2 ARAP3 NOTUM TECPR2 SMOX TMEM220	6.33e-05	161	188	6	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A UBASH3A TBL1XR1 FCHO1 CELSR1 CD226	6.77e-05	163	188	6	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A UBASH3A TBL1XR1 FCHO1 CELSR1 CD226	6.77e-05	163	188	6	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAPSA SFTPB KLK14 PIWIL4 RYR3 TMEM220	6.77e-05	163	188	6	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NAPSA SFTPB CPB2 B3GNT8 NOTUM C11orf96	7.01e-05	164	188	6	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NAPSA SFTPB CPB2 B3GNT8 NOTUM C11orf96	7.01e-05	164	188	6	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA CPB2 GALR2 NOTUM CHRDL1 PROC	7.75e-05	167	188	6	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SPAG4 THSD7A GRIK1 OXTR ECE2 PDE11A	7.75e-05	167	188	6	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA CPB2 GALR2 NOTUM CHRDL1 PROC	8.27e-05	169	188	6	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	ASK428-Epithelial-Secretory\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	SPAG4 KLK10 SH2D3A KLK14 ABLIM3 LIPT2	8.54e-05	170	188	6	9e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	TTC28 ADGRB3 TLR9 ALG1L2 DCLK2 PROC	8.54e-05	170	188	6	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA CPB2 GALR2 IL17RE CHRDL1 PROC	8.82e-05	171	188	6	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 KLK10 CAMK2B SSTR4 M1AP WNT10A	8.82e-05	171	188	6	e780e63510ca47036bc36ca40ecff4098596ee9e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	9.11e-05	172	188	6	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLK10 TMCO4 CELSR2 TECPR2 PGAP2 WNK2	9.11e-05	172	188	6	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7A NDST4 GRIK1 RGS12 RYR3 ECE2	9.41e-05	173	188	6	af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	9.71e-05	174	188	6	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF1 CLSTN1 PGAP2 PAN3 ZSWIM4 MFSD5	1.00e-04	175	188	6	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	MXRA8 ADGRB3 NDST4 ADGRG6 KLK4 NOTUM	1.03e-04	176	188	6	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA TLR9 FCHO1 B3GNT8 WNT10A CARD11	1.03e-04	176	188	6	9b58734017ceabe81f490dd0b9f3192bc903d455
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	MXRA8 ADGRB3 NDST4 ADGRG6 KLK4 NOTUM	1.03e-04	176	188	6	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBRSL1 TBC1D8 SLC4A1AP DCLRE1A TMEM39A PAN3	1.03e-04	176	188	6	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP26A1 GALR2 GJD4 CILP2 NOTUM BMP15	1.03e-04	176	188	6	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-CLDN10+_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 CPB2 CELA3B CELA3A WNT10A WNK2	1.13e-04	179	188	6	7eca1e19ae6b5b1f18c721691dc3e860705628f2
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA TLR9 FCHO1 B3GNT8 WNT10A CARD11	1.13e-04	179	188	6	de3245e1ee269e422de0308d0dd3623e4e9eb182
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NAPSA SFTPB TSPEAR BMP1 MRPL14 NANS	1.13e-04	179	188	6	7db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA TLR9 FCHO1 B3GNT8 WNT10A CARD11	1.13e-04	179	188	6	c41c11171dfb40e5ddea6bf97d9373eb03a2321b
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPIG6B UBASH3A LYST SH2D5 CD226 SMOX	1.17e-04	180	188	6	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPIG6B UBASH3A LYST SH2D5 CD226 SMOX	1.17e-04	180	188	6	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	AT1-AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FAM178B MXRA8 GABBR2 GJD4 WNT10A KLK1	1.17e-04	180	188	6	3c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A DNAH7 TBC1D8 OXTR TEX26 NQO1	1.17e-04	180	188	6	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPIG6B UBASH3A LYST SH2D5 CD226 SMOX	1.17e-04	180	188	6	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT9A WDR54 ADGRG6 EFNA4 TECPR2 WDR62	1.21e-04	181	188	6	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 CR1 CDC14A NQO1	1.24e-04	182	188	6	cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	1.28e-04	183	188	6	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	1.28e-04	183	188	6	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH4A MPIG6B HPDL NOTUM IL17RE KLK1	1.28e-04	183	188	6	2df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	1.28e-04	183	188	6	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 KLK10 CAMK2B FCHO1 NQO1 WNT10A	1.32e-04	184	188	6	e0beb016823514eebdbfc13beb0807efb4470f08
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A FAM178B CELA3B EFNA4 OXTR NQO1	1.32e-04	184	188	6	9365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCell	21-Trachea-Mesenchymal-Airway_Smooth_Muscle\|Trachea / Age, Tissue, Lineage and Cell class	SGCA MXRA8 ADGRB3 ABLIM3 NOTUM CHRDL1	1.32e-04	184	188	6	86a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A FAM178B CELA3B EFNA4 OXTR NQO1	1.32e-04	184	188	6	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A FAM178B CELA3B EFNA4 OXTR NQO1	1.32e-04	184	188	6	204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A FAM178B CELA3B EFNA4 OXTR NQO1	1.32e-04	184	188	6	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NAPSA CPB2 UBASH3A FCHO1 CARD11	1.33e-04	116	188	5	f7f0cd61723c94586504b656a8d4e098e98d8e23
ToppCell	megakaryocytic-Platelet\|megakaryocytic / Lineage and Cell class	ABLIM3 PTPRJ TECPR2 CD226 DCLRE1A SMOX	1.36e-04	185	188	6	436f0ab9016c5b8b7315d5974de80af6b3a999d2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7A NDST4 GRIK1 RGS12 NETO2 ECE2	1.36e-04	185	188	6	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7A TTC28 NDST4 GRIK1 RGS12 ECE2	1.36e-04	185	188	6	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 MXRA8 TSPEAR CR1 CDC14A RYR3	1.36e-04	185	188	6	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SFTPB UBASH3A TREM2 TMEM39A HCCS TECPR1	1.40e-04	186	188	6	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHBDD1 TIMD4 SFTPB TXNDC11 NANS KLK1	1.40e-04	186	188	6	a67e818c5ab682c2058fccc85f3fade0e11cb56e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM178B PIWIL4 CSMD3 ADGRG6 CHRDL1 WNK2	1.44e-04	187	188	6	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 THSD7A MXRA8 CR1 CDC14A RYR3	1.44e-04	187	188	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP10 KDM5C FPR2 ARAP3 JRK WDR62	1.44e-04	187	188	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A CLSTN1 CELSR1 CELSR2 WNT10A RPL3	1.53e-04	189	188	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	mild_COVID-19-Platelet\|World / disease group, cell group and cell class (v2)	ILK MPIG6B ABLIM3 OXTR DCLRE1A SMOX	1.53e-04	189	188	6	038ec3c266b89416bb5b774ba522d916394961da
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	SGCA MXRA8 ABLIM3 BMP1 WNT10A CARD11	1.53e-04	189	188	6	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCA RYR3 CILP2 GSG1L MYO18B WNK2	1.53e-04	189	188	6	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCA RYR3 CILP2 GSG1L MYO18B WNK2	1.53e-04	189	188	6	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 TTC28 SGCA MXRA8 HMGCLL1 SEZ6L	1.57e-04	190	188	6	591310e615700321a010a4b90405cbbbbdb3aade
Computational	Genes in the cancer module 107.	NAPSA KLK10 CPB2 BMP1 CELA3A PROC	5.28e-05	79	91	6	MODULE_107
Computational	Neighborhood of RBBP8	CAMK2B CAMK2G CLOCK FCHO1 JRK BRD1 ECE2 WDR62 SEZ6L	7.64e-05	213	91	9	MORF_RBBP8
Computational	Catabolic peptidases.	NAPSA KLK10 CPB2 BMP1 CELA3A PROC	1.03e-04	89	91	6	MODULE_209
Computational	Genes in the cancer module 172.	NAPSA KLK10 CPB2 BMP1 CELA3A PROC	1.57e-04	96	91	6	MODULE_172
Computational	Serine proteases.	KLK10 CELA3A KLK1 PROC	3.15e-04	39	91	4	MODULE_109
Computational	Neighborhood of RFC5	TPP2 CAMK2G CRHR1 JRK WDR62	5.05e-04	78	91	5	MORF_RFC5
Computational	Neighborhood of FOSL1	CAMK2G FPR2 CPB2 GRIK1 CLOCK CRHR1 RYR3 SIX6 JRK BRD1 SEZ6L	6.08e-04	406	91	11	MORF_FOSL1
Computational	Neighborhood of IL13	CAMK2G FPR2 CRHR1 JRK BRD1 ECE2 WDR62 SEZ6L	8.04e-04	234	91	8	MORF_IL13
Computational	Neighborhood of JAG1	CLOCK JRK ECE2 WDR62 SEZ6L	1.24e-03	95	91	5	MORF_JAG1
Computational	Neighborhood of CDC2L5	CAMK2G JRK BRD1 ECE2 WDR62 SEZ6L	1.27e-03	142	91	6	MORF_CDC2L5
Computational	Neighborhood of JAK3	CAMK2G JRK ECE2 WDR62 SEZ6L	1.30e-03	96	91	5	MORF_JAK3
Drug	diisopropylfluorophosphate	TPP2 KLK10 CAMK2B KLK14 CPB2 PRSS58 PRSS36 CELA3B KLK4 CELA3A PRSS45P TPSG1 KLK1 PROC	3.54e-07	321	183	14	CID000005936
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	9.69e-06	46	183	5	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	7.08e-05	69	183	5	DOID:1682 (implicated_via_orthology)
Disease	chronic kidney disease (is_implicated_in)	CPB2 TLR9 KLK1	8.12e-05	14	183	3	DOID:784 (is_implicated_in)
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1	1.14e-04	3	183	2	DOID:0050155 (implicated_via_orthology)
Disease	Antiglaucoma preparations and miotics use measurement	THSD7A SIX6 PTPRJ	5.49e-04	26	183	3	EFO_0009944
Disease	HMG CoA reductase inhibitor use measurement	TIMD4 CYP26A1 RGS12 CELSR2 NQO1 SMAD3	1.20e-03	189	183	6	EFO_0009932
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 KDM5C CUL7 CSMD3 CARD11	1.24e-03	128	183	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 KDM5C CUL7 CSMD3 CARD11	1.24e-03	128	183	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 KDM5C CUL7 CSMD3 CARD11	1.24e-03	128	183	5	C1266044
Disease	Papillary Renal Cell Carcinoma	DNHD1 KDM5C CUL7 CSMD3 CARD11	1.24e-03	128	183	5	C1306837
Disease	Renal Cell Carcinoma	DNHD1 KDM5C CUL7 CSMD3 CARD11	1.24e-03	128	183	5	C0007134
Disease	Autistic Disorder	KDM5C CUL7 GABBR2 CSMD3 TBL1XR1 DIPK2A OXTR	1.27e-03	261	183	7	C0004352
Disease	tooth agenesis (is_implicated_in)	TSPEAR WNT10A	1.67e-03	10	183	2	DOID:0050591 (is_implicated_in)
Disease	systolic blood pressure, self reported educational attainment	THSD7A CDC14A	1.67e-03	10	183	2	EFO_0004784, EFO_0006335
Disease	Cocaine Dependence	ILK CAMK2B CLOCK CRHR1 SMAD3	1.79e-03	139	183	5	C0600427
Disease	cocaine use	GRIK1 CLOCK	2.03e-03	11	183	2	C3496069
Disease	revision of total hip arthroplasty, aseptic loosening	ICE1 GABBR2 CELSR1	2.26e-03	42	183	3	EFO_0010725, EFO_0020973
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 KDM5C CUL7 CSMD3 CARD11	2.35e-03	148	183	5	C0279702
Disease	Oligospermia	PIWIL4 CDC14A	2.42e-03	12	183	2	C0028960
Disease	Crohn's disease of large bowel	FPR2 TLR9 SMAD3	2.58e-03	44	183	3	C0156147
Disease	IIeocolitis	FPR2 TLR9 SMAD3	2.58e-03	44	183	3	C0949272
Disease	Crohn's disease of the ileum	FPR2 TLR9 SMAD3	2.58e-03	44	183	3	C0267380
Disease	Regional enteritis	FPR2 TLR9 SMAD3	2.58e-03	44	183	3	C0678202
Disease	toxic shock syndrome (is_implicated_in)	SFTPB PROC	2.85e-03	13	183	2	DOID:14115 (is_implicated_in)
Disease	caudate nucleus measurement, functional brain measurement, response to reward	CSMD3 CELSR1 OXTR	3.11e-03	47	183	3	EFO_0007849, EFO_0008387, EFO_0008396
Disease	Crohn Disease	FPR2 TLR9 SMAD3	3.71e-03	50	183	3	C0010346
Disease	Major Depressive Disorder	GABBR2 CLOCK GALR2 CRHR1 OXTR PDE11A	4.20e-03	243	183	6	C1269683
Disease	familial hyperlipidemia	TIMD4 CYP26A1 CILP2 CELSR2	4.35e-03	106	183	4	MONDO_0001336
Disease	Colorectal Carcinoma	OBSCN TSPEAR TLR9 CSMD3 CDC14A GJD4 SLC22A9 ARAP3 CD226 NQO1 SMAD3	4.57e-03	702	183	11	C0009402
Disease	response to statin	ADGRB3 GRIK1 CELSR2	5.11e-03	56	183	3	GO_0036273
Disease	coronary artery disease, factor VII measurement	MPIG6B FCHO1 CELSR2 SMAD3	5.12e-03	111	183	4	EFO_0001645, EFO_0004619
Disease	vitamin D measurement	NPHS1 KLK10 CYP26A1 FBRSL1 CILP2 CELSR2 KLHL8	5.15e-03	336	183	7	EFO_0004631
Disease	heel bone mineral density, urate measurement	TMEM135 TBC1D8 IL17RE BRD1 PDE11A	5.66e-03	182	183	5	EFO_0004531, EFO_0009270
Disease	Unipolar Depression	GABBR2 CLOCK GALR2 CRHR1 OXTR PDE11A	5.71e-03	259	183	6	C0041696
Disease	factor XI measurement, coronary artery disease	MPIG6B FCHO1 CELSR2 SMAD3	5.80e-03	115	183	4	EFO_0001645, EFO_0004694
Disease	breast cancer (is_marker_for)	KDM5C WNT9A TLR9 KLK4 NQO1	6.06e-03	185	183	5	DOID:1612 (is_marker_for)
Disease	Cocaine-Related Disorders	ILK CAMK2B CRHR1 SMAD3	6.16e-03	117	183	4	C0236736

Protein segments in the cluster

Peptide	Gene	Start	Entry
FIQTPTWCIVHAAGS	C21orf140	66	B9A014
ATKGHLSQIAPLCWE	ERVPABLB-1	201	P60509
NHILRCPAGVSKWAV	EPG5	481	Q9HCE0
ASILSQKPGRWCAVH	FBRSL1	581	Q9HCM7
LTGSEVWHPICKQAA	ABLIM3	251	O94929
HVVCALWIPEVGFAN	BRD1	291	O95696
AVGKWFSPLSCHQLL	ARAP3	781	Q8WWN8
NCIWTIISDPGSRIH	CSMD3	746	Q7Z407
WSGAILAHCIVDLPS	LINC00269	36	Q8N2A0
AALVQPHTGKLCWFL	PGLS	226	O95336
VSPSQFGCHVLCTWL	ADGRB3	161	O60242
QFSHCRVWRSPALIV	C2orf48	71	Q96LS8
HFQHIQVCIPWLEGR	ALG1L2	121	C9J202
HAEIIAWIRICRPGS	CDC14A	301	Q9UNH5
VPHSVWGCANCRVVL	ADGRG6	31	Q86SQ4
SICNALEVPHIQTRW	GRIK1	121	P39086
AFLTTHWCQGTQRVP	GSG1L	26	Q6UXU4
LPFDRHDWIINRCGT	HCCS	206	P53701
RTKPVCVFWNHSLAV	CELSR1	2406	Q9NYQ6
KPICVFWNHSILVSG	CELSR2	2316	Q9HCU4
HPSKIETQLVVGACW	CLSTN1	491	O94985
QLWVRRCFPHVHAVS	DNHD1	1381	Q96M86
FTVHWTTILGICRPI	BVES-AS1	6	Q5T3Y7
CIWRIQVSEGFHVGL	BMP1	461	P13497
VHCFPISARLGEWQA	RANBP10	241	Q6VN20
STQRTVWHRPQGCDI	ARHGAP39	86	Q9C0H5
AGVWAHCRPQLTATF	KIRREL3-AS3	226	Q8N7Y1
ENELFCSGVLVHPQW	KLK4	51	Q9Y5K2
CSGVLVHPQWVLSAA	KLK4	56	Q9Y5K2
VPLQLSAHWQCGATL	FCHO1	751	O14526
LHCRARGVPNIVFTW	NPHS1	861	O60500
VPQRYVWRFCIGLHS	PGAP2	71	Q9UHJ9
VWRFCIGLHSAPRFL	PGAP2	76	Q9UHJ9
QFCFIWRAISITPVH	CT55	226	Q8WUE5
VQPLPFWCSHISRLV	ESPNL	586	Q6ZVH7
KTITVVHQPWCNITG	PTPRJ	161	Q12913
ATIIHPRLCWQLASV	OR2H2	131	O95918
CSWFIRANPGEIITI	LRP12	76	Q9Y561
IVHIALPSWADICTN	M1AP	26	Q8TC57
STFQCGGILVHRQWV	KLK1	46	P06870
QWVITAAHCGRPILQ	KLK14	76	Q9P0G3
CFTHNCWVLKGIRIP	MST1L	671	Q2TV78
CVLHPVWAQNHRTVS	FPR2	126	P25090
SGPEVSVRLCHQWAL	IL17RE	196	Q8NFR9
CSLHPFQISFRQLGW	BMP15	291	O95972
VEARCTAGQILSHPW	DCLK2	636	Q8N568
PVSHLRFWLIQGVCV	GJD4	71	Q96KN9
SGLFWRVTCPHLRSI	ECE2	66	P0DPD6
GVTIGFVAEHWNLCR	PLSCR4	216	Q9NRQ2
PVLNRWELVGSVSHC	KLHL8	576	Q9P2G9
VACAWNAVPSHVFRR	JRK	366	O75564
PRACRHAVIAVWIAG	OR14J1	136	Q9UGF5
GFHIRSVLCVPIWNS	PDE11A	506	Q9HCR9
QCIWEHGPTSLLVSI	CRISPLD2	96	Q9H0B8
PTFWPVFREQLCRHT	CUL7	971	Q14999
VLVLSRHSWPVASIC	CUL7	1391	Q14999
RWVCSLPFGHVQFSE	EFNA4	96	P52798
LCTSGVVRLHINSWL	NPRL3	211	Q12980
TLQRRCLVPGWYAVH	NDST4	736	Q9H3R1
SSFTFWVPLCGHRLV	OR2J2	161	O76002
WLGCLVASAPQVHIF	OXTR	161	P30559
NVILWPIQSGILHFC	NQO1	166	P15559
CIQPSVIRHVRSWSN	ALDH18A1	31	P54886
GWVSRVDHLTLACTP	HPDL	156	Q96IR7
GAVAFLRSTLCAQPW	OBSCN	7896	Q5VST9
QVKGTSLPRALHCWD	NOTUM	401	Q6P988
LACGAVLIHPSWVLT	PROC	236	P04070
LEGVPVECTHSFIWN	POP1	541	Q99575
RPCHGALVSESWVLA	PRSS36	346	Q5K4E3
GAPWIDLSHIISCLN	PAN3	826	Q58A45
FCKIISREHQWPIGL	FANCD2OS	126	Q96PS1
ILCVWFGQFPLTRAT	GALR2	256	O43603
ASFCWDHRPVQIITS	G2E3	121	Q7L622
SQLPIWGVRQVHCGS	FAM124B	121	Q9H5Z6
LWLCVNTTHRLPGEG	ICE1	211	Q9Y2F5
RVIRCHTDNTWVPGV	CR2	826	P20023
IDCGIHAREWISPAF	CPB2	176	Q96IY4
ISPAFCLWFIGHITQ	CPB2	186	Q96IY4
RSLWNNSVPVCEHIF	CR1	1306	P17927
ESWHPNLRAFGIVEC	CHRDL1	271	Q9BU40
VQVASRWHVPSDGLC	LINC00315	106	P59091
SLIAPDWVVTAGHCI	CELA3A	61	P09093
VEGWSDLVHCPSQRL	DIPK2A	161	Q8NDZ4
LPRQTWSISESGHIC	CRYBG2	1606	Q8N1P7
RDWPGQTVLCVSQIF	DNAH7	1176	Q8WXX0
SPLHWACREGRSAVV	ILK	36	Q13418
AIQCHWSQRPAVIGD	DDX50	366	Q9BQ39
SLIAPDWVVTAGHCI	CELA3B	61	P08861
SPEVHQSNVGWCRLV	CRHR1	206	P34998
VWADPHNATLIFRVC	LYST	1551	Q99698
VWPLASGRLGQCLHT	FBXW4	226	P57775
VALLCSLAPQQVHRW	MBOAT4	71	Q96T53
GCFLAWETRNVSIPA	GABBR2	671	O75899
HWPASVRTILGSGCL	CYP26A1	111	O43174
PCFNGRVVSWLVLAE	DVL1	71	O14640
SLIGQTPRWHVFECL	DCLRE1A	131	Q6PJP8
VSNCSHGRWSVIVIP	CD226	196	Q15762
QLWTVAPGFSLCLEH	HELZ2	1901	Q9BYK8
WLGRHCPTVSFVLRA	B3GNT8	231	Q7Z7M8
QCSCGRWITPAFQIH	DUSP12	306	Q9UNI6
LLENFSAAIPGHRCW	SLC22A11	36	Q9NSA0
SVHNRAIRNCPWTVA	SART3	366	Q15020
FIRLVSDPCRWVHQA	PPP4R1L	246	Q9P1A2
AHWTIQRCSGPVTLH	CARD11	736	Q9BXL7
ALKHPWVCQRSTVAS	CAMK2G	266	Q13555
GVLNWFRVPLHSLAC	MFSD5	376	Q6N075
LTWFEHIVPCGLVGT	LIPT2	176	A6NK58
QRPVLVHCSDGWDRT	MTMR3	406	Q13615
CQQWTASFPHLRILG	FAM149B1	131	Q96BN6
ATIIHPRLCWQLASV	OR2H1	131	Q9GZK4
PRFCHLLAVASWVSG	OR2J3	141	O76001
SWLGGFCHSIIQILV	OR4B1	146	Q8NGF8
VACIHWETSQLSGLP	HMGCLL1	61	Q8TB92
DTHPIQRCRFWGKIL	RSPH4A	346	Q5TD94
QQPIHTCRFWGKILG	RSPH6A	336	Q9H0K4
ALKHPWVCQRSTVAS	CAMK2B	266	Q13554
HVCGGSLLSPQWVLT	TPSG1	61	Q9NRR2
VTIRCILGQPSHWNG	SEZ6L	911	Q9BYH1
PNRFACWVELVAIHL	RHBDD1	171	Q8TEB9
CAGVLIHPLWVITAA	PRSS58	41	Q8IYP2
LLTLVPRGWDAHTTC	SFTPB	346	P07988
SVANVIDNPWGVCLH	TMCO4	361	Q5TGY1
PGGIQTRAVWCAHVE	THSD7A	76	Q9UPZ6
GLWGPFTCVSRVLSH	MRPL14	6	Q6P1L8
LWCVYVHETVLGIPR	TCAF1	781	Q9Y4C2
VACIGAWHPARVAFS	RPL3	251	P39023
PGFCTAIVSLKWRLH	RGP1	311	Q92546
TAFIPGHRCWVHILD	SLC22A9	41	Q8IVM8
WCPSLQEVREAFHSL	FAM178B	366	Q8IXR5
VNLSCGGVSHPIRWV	MPIG6B	31	O95866
LTENIWAFAGISRPC	SH2D5	291	Q6ZV89
VGCVASVNPRITRWF	PIWIL4	636	Q7Z3Z4
HWPFGSVLCRAVLSV	SSTR4	111	P31391
LPRTIWDGEQKTHCF	SIX6	121	O95475
RWVGGQHPCFIIAEI	NANS	11	Q9NR45
GIKHIPATQCGIWVR	NETO2	36	Q8NC67
IQILSNWGHPRFTCL	SPAG4	401	Q9NPE6
LAPHFRVDWCNVTLV	SGCA	236	Q16586
RGHESEVFICAWNPV	TBL1XR1	166	Q9BZK7
QWNSRPEFIVCTHTV	CLOCK	361	O15516
ERVHLNPTRGFWCLN	CILP2	111	Q8IUL8
VLIVSTLHQPGGWIC	C11orf96	21	Q7Z7L8
PSWVVTAAHCIQGTK	PRSS45P	26	Q7RTY3
TRTYTWLGALPVLHC	RNF213	686	Q63HN8
TLIHQIFGGCWRSQI	USP17L3	191	A6NCW0
VQRPIISICWGHRDS	TULP4	341	Q9NRJ4
TLIHQIFGGCWRSQI	USP17L4	191	A6NCW7
CGFNQRWLPVHVLRE	RGS12	531	O14924
AWIILCHSSSKNPVG	TMEM220	106	Q6QAJ8
GLVNCNWLFLKSVPH	TLR9	41	Q9NR96
AIRIFAGQDPSCVWV	RYR3	1331	Q15413
NPVISCRWRGSALHF	SH2D3A	46	Q9BRG2
RQTVTSTPCWIELHL	SMAD3	386	P84022
VRLHTGERPFVCNWF	SP2	546	Q02086
TIWPQGVLVRHSRCL	TMEM39A	376	Q9NV64
VQISCGPHDLLWATL	TECPR1	246	Q7Z6L1
QLVSPWTCGAHTEIL	TBC1D8	866	O95759
PEVQGVSRILAHWAC	VPS16	476	Q9H269
CPNSSVWVRAGHRTL	GEMIN5	1296	Q8TEQ6
QLGKPVRCIHWDQAS	SMOX	256	Q9NWM0
EATHWPNSGRICEVI	TPP2	331	P29144
GHTWHPSCRVSFLQI	TMEM135	16	Q86UB9
WEHVPGLQACQLALS	TECPR2	1306	O15040
TLIHQIFGGCWRSQI	USP17L1	191	Q7RTZ2
KGQSHICATRQPAWI	UBQLNL	366	Q8IYU4
RGHESEVFICAWNPV	TBL1Y	176	Q9BQ87
EKGPCQRVVSTHNLW	TREM2	56	Q9NZC2
LQCEIFHQLGWDPVR	MYO18B	1081	Q8IUG5
RLILTAAHCIQPTWT	PRSS48	61	Q7RTY5
CNTVVLPQWHSFSRT	TXNDC11	451	Q6PKC3
DSCVFIWHLGPEITN	WDR62	736	O43379
SVQLWRLPGCHEFLA	TTC28	1886	Q96AY4
VRTCWRQLAPFHEVG	WNT9A	226	O14904
TLIHQIFGGCWRSQI	USP17L8	191	P0C7I0
TGWIHAVLTPVDCLA	PHF8	351	Q9UPP1
SLCHPGWSVVAQSLL	TPTE2P1	106	Q5T6R2
FVAVHSLPTVGCRDW	TSPEAR	626	Q8WU66
AVSGEPLVHWCTQQL	TRIP4	6	Q15650
PLVHWCTQQLRKTFG	TRIP4	11	Q15650
CLSVHQPWASLLVRG	TRIP4	436	Q15650
IFLWTLPHCQQTGTL	TEX26	106	Q8N6G2
CWQVTPEFRTVGALL	WNT10A	276	Q9GZT5
LHTGKRWFIICPVAE	WNK2	1306	Q9Y3S1
RQLCASVGSVWFVLP	TRAPPC10	756	P48553
VLWGRKAPTHCISAV	WDR7	11	Q9Y4E6
VLGHRVTLPCLYSSW	TIMD4	31	Q96H15
TLCSRIPQVTTHWLE	UNC45A	851	Q9H3U1
TLIHQIFGGCWRSQI	USP17L2	191	Q6R6M4
HFICVGTWSGRVLVF	WDR54	131	Q9H977
QLARAIPLGHSCQWT	UBASH3A	251	P57075
FPRWFILGHLETRQC	ZSWIM4	596	Q9H7M6
IQQESPLRTHWTGVC	ZNF776	71	Q68DI1
QDWFHGRCVSVPRLL	KDM5C	1206	P41229
VLTAAHCGNKPLWAR	KLK10	81	O43240
PALLTCVNRGHVWTD	MXRA8	181	Q9BRK3
EQGHSTWLCRVRLPV	SLC4A1AP	391	Q9BWU0
NLWVPSRRCHFFSVP	NAPSA	101	O96009