Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK4 GRK6

1.26e-057162GO:0004703
GeneOntologyMolecularFunction14-3-3 protein binding

KCNH1 HLA-E

5.09e-0442162GO:0071889
DomainGPCR_kinase

GRK4 GRK6

1.44e-057162IPR000239
DomainRGS

GRK4 GRK6

4.03e-0435162PF00615
DomainRGS

GRK4 GRK6

4.03e-0435162SM00315
DomainRGS

GRK4 GRK6

4.26e-0436162PS50132
DomainRGS

GRK4 GRK6

5.01e-0439162IPR016137
DomainAGC-kinase_C

GRK4 GRK6

1.03e-0356162IPR000961
DomainAGC_KINASE_CTER

GRK4 GRK6

1.03e-0356162PS51285
DomainS_TK_X

GRK4 GRK6

1.03e-0356162SM00133
DomainKinase-like_dom

ALPK2 GRK4 GRK6

1.03e-02542163IPR011009
PathwayKEGG_ENDOCYTOSIS

GRK4 GRK6 HLA-E

2.34e-04181103M1519
Pubmed

Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor.

GRK4 GRK6

1.19e-06416210379886
Pubmed

The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.

GRK4 GRK6

2.97e-06616210506199
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK4 GRK6

4.16e-0671628672451
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK4 GRK6

4.16e-06716211517230
Pubmed

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis.

UHRF1 VWC2

5.44e-052416237414952
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

VWC2 VPS13C POP1 PPFIA3

2.96e-0473616429676528
CoexpressionZHANG_TARGETS_OF_EWSR1_FLI1_FUSION

MYO10 PPFIA3 HLA-E

1.92e-0587163M18322
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

MYO10 EML1 HLA-E MCTP1

5.98e-0719516450a193475db1bb1e05b8590225a553688c372c14
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

MYO10 ALPK2 EML1

1.64e-051411637671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

MYO10 ALPK2 EML1

2.53e-0516316326661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

MYO10 ALPK2 EML1

2.53e-051631636ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

MYO10 EML1 HLA-E

4.05e-05191163c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

MYO10 EML1 HLA-E

4.11e-051921638a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO10 HLA-E MCTP1

4.11e-051921635a0615fdc217554ccd611504b16e5d97628e207d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E MCTP1

4.11e-0519216328eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E MCTP1

4.18e-051931636a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

EML1 HLA-E MCTP1

4.18e-05193163e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

EML1 HLA-E MCTP1

4.24e-051941637b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

EML1 HLA-E MCTP1

4.31e-0519516319e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E MCTP1

4.37e-05196163145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

EML1 HLA-E MCTP1

4.44e-05197163ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

EML1 HLA-E MCTP1

4.44e-05197163f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

VPS13C HLA-E MCTP1

4.51e-05198163dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO10 HLA-E MCTP1

4.57e-05199163b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|PND01-03-samps / Age Group, Lineage, Cell class and subclass

VWC2 MCTP1

9.98e-04132162617644597726e881cd343e57f6edb5a98473b421
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

EML1 PPFIA3

1.04e-03135162cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

EML1 PPFIA3

1.09e-0313816205de2cef97c0912fb23f138dd45348f565a14d74
ToppCellCOVID-19-Mast_cells-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

UHRF1 PPFIA3

1.14e-031411620fc06c2325249aa4ae65c0ace1ec3f953372f2e4
ToppCellCOVID-19_Mild-PLT_3|World / Disease Group and Platelet Clusters

UHRF1 HLA-E

1.23e-031471629d3271aa735ddb6f32ab864d7afcfb0f8754383b
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UHRF1 ALPK2

1.28e-0315016257f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCellCOVID-19-Mast_cells-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

VWC2 POP1

1.28e-0315016210697c2d22cb25376827cc7c570ff1adc94c1acd
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UHRF1 ALPK2

1.32e-031521620c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UHRF1 EML1

1.37e-031551625d157478669b609e1f0f0a75afd0112571fc2c46
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

UHRF1 VWC2

1.37e-031551627c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

UHRF1 PPFIA3

1.39e-03156162ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UHRF1 MCTP1

1.39e-03156162af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UHRF1 VWC2

1.39e-031561621928c86deb3bcd01db4ae76919a351066aadb39a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E

1.39e-03156162f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

VWC2 KCNH1

1.39e-03156162fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

UHRF1 ALPK2

1.44e-0315916285501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ALPK2 MCTP1

1.44e-03159162210ac7fa89514a84f38d9f42254e38fbc2bc5f42
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VWC2 ARMCX1

1.44e-031591626115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VWC2 ARMCX1

1.46e-03160162a90eb621481fd07a821495db07d1032e109fd386
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UHRF1 HLA-E

1.46e-03160162830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ALPK2 MCTP1

1.46e-03160162c9fe3438f747e2a98e3f27a56ba4c12a3789c2f2
ToppCellHealthy/Control-CD8+_T_naive|Healthy/Control / Disease group and Cell class

MYO10 EML1

1.46e-03160162e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UHRF1 KCNH1

1.48e-03161162f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALPK2 GRK6

1.48e-0316116298be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALPK2 GRK6

1.48e-031611627af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALPK2 MCTP1

1.50e-0316216293bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellPBMC-Severe-Myeloid-cDC-cDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UHRF1 ARMCX1

1.51e-03163162ec8336b68c8369e27d507c04c827be07bb48a7f6
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VWC2 MYO10

1.53e-03164162f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWC2 MCTP1

1.53e-031641622c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VWC2 MYO10

1.53e-03164162b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALPK2 PPFIA3

1.55e-031651628a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-E MCTP1

1.55e-03165162a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX1 MCTP1

1.57e-031661627a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX1 MCTP1

1.57e-03166162bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

EML1 HLA-E

1.59e-031671625af9127bae05768a5164d5708a4ad37edca99324
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWC2 ARMCX1

1.59e-03167162f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

VWC2 MCTP1

1.63e-03169162fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

VWC2 MCTP1

1.64e-03170162c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 ALPK2

1.64e-031701627653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

EML1 HLA-E

1.66e-03171162bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UHRF1 ALPK2

1.66e-031711621eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

KCNH1 ARMCX1

1.68e-03172162dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

KCNH1 ARMCX1

1.68e-0317216204fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UHRF1 POP1

1.68e-0317216276c06a968d3333441eed103abef1e636a1c3e7a1
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E

1.68e-0317216294093d356b0252b440deda4e1b0ac332b31513f6
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UHRF1 MYO10

1.68e-0317216220ea9db009370aa6235365ce93e153eb5b28db94
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

GRK6 HLA-E

1.70e-03173162b06d6e7acb7086bb99600b680cf404c0ef06b52c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E

1.70e-03173162f193c63cc536d891c9d23043765e320252bb6e65
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML1 HLA-E

1.70e-03173162afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO10 ARMCX1

1.70e-03173162090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALPK2 GRK6

1.72e-03174162fbf998dd33ac27dad7639ea85fca393ba2835307
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

VWC2 MCTP1

1.72e-03174162e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO10 ARMCX1

1.72e-03174162a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

VWC2 MCTP1

1.72e-0317416205525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EML1 MCTP1

1.72e-031741626b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALPK2 GRK6

1.72e-031741628bdf5a97faf1cf0426d1a8851f8a3e27578f7598
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UHRF1 PPFIA3

1.74e-03175162a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

VWC2 MYO10

1.74e-03175162eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UHRF1 ARMCX1

1.74e-03175162db6be3e9e339918418fcaf9001ea15207aa6c993
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UHRF1 ARMCX1

1.74e-031751628acac10c9eedccebcf3a3fe31bfee35afa54579f
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

VWC2 MYO10

1.74e-03175162ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|356C / Donor, Lineage, Cell class and subclass (all cells)

GRK6 HLA-E

1.76e-031761629399e174d14e81cc977fcb48facf844ee6726603
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

VWC2 MCTP1

1.76e-03176162473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-E MCTP1

1.76e-031761621df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK4 MCTP1

1.80e-03178162f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 VPS13C

1.80e-0317816201dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UHRF1 ARMCX1

1.80e-031781625ac5257d88fa0dc67714881d6f005f6cea925710
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO10 MCTP1

1.82e-0317916214fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADH6 ALPK2

1.82e-03179162d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 EML1

1.84e-0318016228bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

EML1 HLA-E

1.84e-03180162162cec1734e560c068cd61717e40e18dcf92308c
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

EML1 HLA-E

1.84e-0318016233c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 EML1

1.84e-03180162f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

MYO10 VPS13C

1.84e-03180162adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 EML1

1.84e-0318016253db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

EML1 HLA-E

1.84e-03180162b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EML1 MCTP1

1.84e-0318016230cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX1 MCTP1

1.86e-031811624d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO10 MCTP1

1.88e-031821620346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-E MCTP1

1.88e-03182162d996ceb77c83591df4cef144ca72862f31d9777f
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO10 MCTP1

1.88e-031821627b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX1 MCTP1

1.90e-031831623427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell3'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-E MCTP1

1.90e-03183162f8212bf8a8b8312434ae030261c558c147f61747
ComputationalNeighborhood of CD48

GRK6 HLA-E

5.56e-0432122GNF2_CD48
ComputationalNeighborhood of VAV1

GRK6 HLA-E

7.05e-0436122GNF2_VAV1
ComputationalNeighborhood of INPP5D

GRK6 HLA-E

1.01e-0343122GNF2_INPP5D
ComputationalNeighborhood of HLA-C

GRK6 HLA-E

1.20e-0347122GNF2_HLA_C
ComputationalNeighborhood of PTPN6

GRK6 HLA-E

1.20e-0347122GNF2_PTPN6
ComputationalNeighborhood of CD53

GRK6 HLA-E

1.82e-0358122GNF2_CD53
ComputationalNeighborhood of PTPRC

GRK6 HLA-E

2.50e-0368122GNF2_PTPRC
ComputationalNeighborhood of STAT6

GRK6 HLA-E

3.36e-0379122GNF2_STAT6
Druglinalool

KCNH1 ALPK2

1.86e-0429162CID000006549
Drug2-phenylethanol

KCNH1 ALPK2

1.99e-0430162CID000006054
DrugLanatoside C [17575-22-3]; Down 200; 4uM; MCF7; HT_HG-U133A

ARMCX1 POP1 PPFIA3

2.65e-041831633963_DN
Drugthapsigargin; Down 200; 0.1uM; MCF7; HT_HG-U133A

MYO10 GRK6 POP1

3.00e-041911637100_DN
DrugDigitoxigenin [143-62-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ARMCX1 POP1 PPFIA3

3.05e-041921634801_DN
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A

ARMCX1 GRK6 POP1

3.05e-0419216323_UP
DrugCarbamazepine [298-46-4]; Down 200; 17uM; PC3; HT_HG-U133A

MYO10 GRK6 PPFIA3

3.10e-041931631805_DN
DrugAnisomycin [22862-76-6]; Down 200; 15uM; MCF7; HT_HG-U133A

ARMCX1 GRK6 PPFIA3

3.14e-041941632658_DN
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; PC3; HT_HG-U133A

ADH6 KCNH1 GRK4

3.19e-041951634634_UP
DrugAdenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; MCF7; HT_HG-U133A

EML1 POP1 PPFIA3

3.19e-041951635359_DN
DrugAceclofenac [89796-99-6]; Down 200; 11.2uM; PC3; HT_HG-U133A

GRK6 EML1 PPFIA3

3.24e-041961637269_DN
DrugBacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A

GRK6 EML1 PPFIA3

3.24e-041961637448_DN
Drugprostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

GRK4 EML1 MCTP1

3.29e-041971636547_DN
DrugMeptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

MYO10 GRK6 PPFIA3

3.29e-041971634774_DN
DrugFluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MYO10 EML1 PPFIA3

3.29e-041971635356_DN
DrugGuaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A

EML1 PPFIA3 MCTP1

3.29e-041971633431_UP
DrugLY294002; Down 200; 10uM; PC3; HG-U133A

ADH6 EML1 PPFIA3

3.29e-04197163429_DN
DrugCortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A

VPS13C GRK6 EML1

3.34e-041981637416_DN
DrugDihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A

GRK6 EML1 POP1

3.34e-041981636228_DN
DrugHydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HG-U133A

GRK6 EML1 PPFIA3

3.34e-041981631906_UP
Drugthioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

GRK6 POP1 PPFIA3

3.34e-041981631655_DN
DrugCefaclor [70356-03-5]; Up 200; 10.4uM; HL60; HT_HG-U133A

MYO10 KCNH1 PPFIA3

3.39e-041991632483_UP
DrugRiboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A

GRK6 EML1 PPFIA3

3.39e-041991632760_DN
DrugBumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A

MYO10 GRK6 EML1

3.39e-041991635542_DN
DrugDelsoline [509-18-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A

GRK6 EML1 PPFIA3

3.39e-041991636075_DN
DrugNaphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; HL60; HG-U133A

VPS13C GRK6 POP1

3.44e-042001631966_DN
DrugICI 182,780; Down 200; 0.01uM; MCF7; HG-U133A

MYO10 GRK6 POP1

3.44e-04200163310_DN
Drugbutirosin A from Bacillus vitellinus; Up 200; 10uM; PC3; HG-U133A

ADH6 MYO10 GRK6

3.44e-04200163666_UP
Drughexanol

KCNH1 ALPK2

6.97e-0456162CID000008103
Diseasevasoactive peptide measurement

KCNH1 GRK6

4.13e-066162EFO_0005196
Diseaseneuroticism measurement, cognitive function measurement

UHRF1 GRK6 MCTP1

3.26e-03566163EFO_0007660, EFO_0008354
Diseasecardiac troponin I measurement

MYO10 GRK6

4.02e-03176162EFO_0010071
Diseasealcohol use disorder (implicated_via_orthology)

GRK4 GRK6

4.91e-03195162DOID:1574 (implicated_via_orthology)
Diseasealcohol use disorder measurement

ADH6 GRK4

5.88e-03214162EFO_0009458
Diseasecortical surface area measurement, neuroimaging measurement

EML1 MCTP1

6.59e-03227162EFO_0004346, EFO_0010736
DiseaseQRS duration

ADH6 EML1

1.11e-02298162EFO_0005055

Protein segments in the cluster

PeptideGeneStartEntry
SGRSLKGSVFGGWKS

ADH6

311

P28332
GGKDLWSKRGSRKSA

ALPK2

521

Q86TB3
AVIWRKKSSGGKGGS

HLA-E

326

P13747
GSGAGSRWSGFKKRK

MCTP1

71

Q6DN14
SKSKGLPKSAWGGGT

NCKAP5L

371

Q9HCH0
GSGRAGKRGRWSGVK

PPFIA3

536

O75145
KKGGGSSTLSRRNWK

MYO10

1221

Q9HD67
GGGGDCAKRKSWARF

KCNH1

826

O95259
SSKGMFRKKGGWKAG

POP1

76

Q99575
FRKKGGWKAGPEGTS

POP1

81

Q99575
SGGGKDRKLISWSGN

EML1

476

O00423
RQGGYGKKSGRSKKW

GRK4

16

P32298
REGGGGNRKGKSKKW

GRK6

16

P43250
AGGRASGKSKGKARS

ARMCX1

161

Q9P291
GSGRDWKSKSGRGLA

VWC2

71

Q2TAL6
KKSADTGEKRGGWFS

VPS13C

461

Q709C8
RTGKGKWKRKSAGGG

UHRF1

641

Q96T88
KWKRKSAGGGPSRAG

UHRF1

646

Q96T88