Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	HEXA MGAM GANC ABHD10 KL EDEM1 OGA	2.65e-05	103	168	7	GO:0004553
GeneOntologyMolecularFunction	phosphatidylserine transfer activity	OSBPL5 OSBPL8	7.04e-05	2	168	2	GO:0140343
GeneOntologyMolecularFunction	Rab GDP-dissociation inhibitor activity	GDI1 GDI2	7.04e-05	2	168	2	GO:0005093
GeneOntologyMolecularFunction	modified amino acid binding	LANCL1 NOX4 ASAP1 FASN OSBPL5 OSBPL8 CPNE1	7.83e-05	122	168	7	GO:0072341
GeneOntologyMolecularFunction	glycosyltransferase activity	HEXA POMT2 LARGE2 TMTC2 ST6GAL1 ST3GAL6 CERCAM GALNT6 UPP2 LARGE1	1.69e-04	288	168	10	GO:0016757
GeneOntologyMolecularFunction	ubiquitin-ubiquitin ligase activity	TRAF6 UBE4A UBR5	1.99e-04	14	168	3	GO:0034450
GeneOntologyMolecularFunction	tripeptidyl-peptidase activity	TPP2 ACE	2.10e-04	3	168	2	GO:0008240
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	HEXA MGAM GANC ABHD10 KL EDEM1 OGA	2.20e-04	144	168	7	GO:0016798
GeneOntologyMolecularFunction	glucosidase activity	MGAM GANC KL	2.47e-04	15	168	3	GO:0015926
GeneOntologyMolecularFunction	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	GJC1 GJC3	4.18e-04	4	168	2	GO:0086077
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM GANC	6.92e-04	5	168	2	GO:0004558
GeneOntologyMolecularFunction	gap junction channel activity involved in cardiac conduction electrical coupling	GJC1 GJC3	6.92e-04	5	168	2	GO:0086075
GeneOntologyMolecularFunction	beta-N-acetylhexosaminidase activity	HEXA OGA	1.03e-03	6	168	2	GO:0004563
GeneOntologyBiologicalProcess	carbohydrate derivative catabolic process	HEXA PDE1A STAB2 ENPP1 ABHD10 AOAH APOBEC3G PGLYRP3 VNN1 MFSD8 EDEM1 OGA UPP2	2.26e-06	323	166	13	GO:1901136
GeneOntologyBiologicalProcess	protein O-linked mannosylation	POMT2 LARGE2 TMTC2 LARGE1	1.43e-05	19	166	4	GO:0035269
GeneOntologyBiologicalProcess	carbohydrate derivative metabolic process	HEXA POMT2 PRPSAP1 LARGE2 TPST2 PDE1A STAB2 GANC PDHA1 ENPP1 ABHD10 AOAH APOBEC3G TMTC2 ST6GAL1 PGLYRP3 FASN ST3GAL6 VNN1 MFSD8 GALNT6 EDEM1 OGA UPP2 LARGE1	1.66e-05	1226	166	25	GO:1901135
GeneOntologyBiologicalProcess	protein O-linked glycosylation	POMT2 LARGE2 TMTC2 ST6GAL1 GALNT6 OGA LARGE1	2.26e-05	105	166	7	GO:0006493
GeneOntologyBiologicalProcess	protein mannosylation	POMT2 LARGE2 TMTC2 LARGE1	4.49e-05	25	166	4	GO:0035268
GeneOntologyBiologicalProcess	mannosylation	POMT2 LARGE2 TMTC2 LARGE1	5.27e-05	26	166	4	GO:0097502
GeneOntologyBiologicalProcess	transcription elongation-coupled chromatin remodeling	IWS1 SUPT6H USP7	5.89e-05	10	166	3	GO:0140673
GeneOntologyBiologicalProcess	symbiont-mediated disruption of host anatomical structure	CSNK2B USP7	1.92e-04	3	166	2	GO:0052111
GeneOntologyBiologicalProcess	maltose metabolic process	MGAM GANC	1.92e-04	3	166	2	GO:0000023
GeneOntologyBiologicalProcess	symbiont-mediated disruption of host cell PML body	CSNK2B USP7	1.92e-04	3	166	2	GO:0075342
GeneOntologyBiologicalProcess	symbiont-mediated disruption of host cellular anatomical structure	CSNK2B USP7	1.92e-04	3	166	2	GO:0052008
GeneOntologyBiologicalProcess	glycoprotein metabolic process	HEXA POMT2 LARGE2 GANC TMTC2 ST6GAL1 ST3GAL6 MFSD8 GALNT6 EDEM1 OGA LARGE1	1.96e-04	430	166	12	GO:0009100
Domain	RabGDI	GDI1 GDI2	7.95e-05	2	167	2	IPR000806
Domain	Glycoside_hydrolase_SF	HEXA MGAM GANC KL OGA	1.09e-04	53	167	5	IPR017853
Domain	Filamin	FLNB FLNC MYCBP2	1.10e-04	11	167	3	PF00630
Domain	FILAMIN_REPEAT	FLNB FLNC MYCBP2	1.10e-04	11	167	3	PS50194
Domain	Filamin/ABP280_rpt	FLNB FLNC MYCBP2	1.10e-04	11	167	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC MYCBP2	1.10e-04	11	167	3	IPR017868
Domain	GPS	PKDREJ ADGRG6 ADGRL2 ADGRL3	2.32e-04	34	167	4	SM00303
Domain	Latrophilin	ADGRL2 ADGRL3	2.37e-04	3	167	2	PF02354
Domain	USP7_C2	USP11 USP7	2.37e-04	3	167	2	PF14533
Domain	USP_C	USP11 USP7	2.37e-04	3	167	2	IPR029346
Domain	GPCR_2_latrophilin_rcpt_C	ADGRL2 ADGRL3	2.37e-04	3	167	2	IPR003334
Domain	GPS	PKDREJ ADGRG6 ADGRL2 ADGRL3	3.24e-04	37	167	4	IPR000203
Domain	GDI	GDI1 GDI2	4.71e-04	4	167	2	PF00996
Domain	GDP_dissociation_inhibitor	GDI1 GDI2	4.71e-04	4	167	2	IPR018203
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 FLNB FLNC SMARCA5 MYCBP2 PDHA1 USP11 BMS1 RPS15 PSMD2 TRRAP GDI1 GDI2 NUP205 FASN UTP18 FAM120A RNPEP UBR5 SUPT6H RCL1 USP7 OSBPL8 CPSF1 ASCC3 NUP160	2.38e-16	653	171	26	22586326
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL2 MYH2 FLNB FLNC MYCBP2 VWA8 PDHA1 USP11 DHX40 BMS1 KDM3B PSMD2 CNKSR2 ATE1 TRRAP PREPL NUP205 IWS1 UTP18 UBR5 SUPT6H CSNK2B FBXO7 USP7 CPNE1 ASCC3 OGA NUP160	1.15e-13	1005	171	28	19615732
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNB FLNC SMARCA5 MYCBP2 PDHA1 MYO9A USP11 DHX40 POLR2B BMS1 RPS15 LANCL1 PTPN23 PSMD2 RHOT2 TRRAP ASAP1 NUP205 WDR47 TGM1 GUF1 FASN UTP18 FAM120A UBR5 CSNK2B RCL1 USP7 CPSF1 AP1G2 ASCC3 NUP160	1.41e-13	1353	171	32	29467282
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PRPSAP1 CUL2 TPP2 MYH2 FLNB VWA8 POLR2B BMS1 RPS15 PSMD2 RHOT2 MAB21L2 IFIT3 NUP205 IWS1 UBE4A NBAS FASN UTP18 FAM120A UBR5 CSNK2B USP7 OSBPL8 ASCC3 ADGRL2 ATP1B3	2.37e-09	1440	171	27	30833792
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL2 SMARCA5 USP11 POLR2B ZMYND8 KDM3B MED1 TRRAP GDI2 NUP205 IWS1 FASN RNPEP UBR5 SUPT6H CDC16 CSNK2B USP7 CPSF1 CPNE1 TAF1 MYO15A	6.35e-09	1014	171	22	32416067
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	HEXA VWA8 NUP210L POLR2B PTPN23 PSMD2 TRRAP GDI2 NUP205 FASN UBR5 ZBTB25 SUPT6H CDC16 RCL1 USP7 CPSF1 OGA NUP160	6.95e-09	754	171	19	35906200
Pubmed	Network organization of the human autophagy system.	CUL2 MYH2 FLNC PDHA1 USP11 ENPP1 ABHD10 PSMD2 GDI1 GDI2 NUP205 RAB3GAP2 USP7 OSBPL8	4.03e-08	437	171	14	20562859
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	HEXA PRPSAP1 CUL2 TPP2 FLNB FLNC PDHA1 USP11 POLR2B RPS15 KDM3B PTPN23 PSMD2 ATE1 DPP8 GDI1 GDI2 NUP205 IWS1 FASN CSNK2B RAB3GAP2 USP7 OGA NUP160	5.42e-08	1455	171	25	22863883
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	CUL2 FLNB FLNC USP11 DHX40 BMS1 RPS15 PTPN23 PSMD2 ATE1 PREPL NUP205 FASN FAM120A UBR5 OSBPL8 ASCC3 EDEM1 ADGRL2 NUP160	7.98e-08	974	171	20	28675297
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRPSAP1 TPP2 SMARCA5 PDHA1 POLR2B ZMYND8 PTPN23 RHOT2 TRRAP NUP205 NBAS FASN UBR5 RAB3GAP2 ASCC3 DNAH5 NUP160	8.31e-08	704	171	17	29955894
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CUL2 SMARCA5 VWA8 USP11 POLR2B ZMYND8 PSMD2 UBE4A UTP18 RNPEP SUPT6H CDC16 RAB3GAP2 OSBPL8 NUP160	1.34e-07	560	171	15	35241646
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNB SMARCA5 PDHA1 POLR2B BMS1 LANCL1 PSMD2 GDI2 NUP205 UBE4A FASN UTP18 FAM120A RNPEP SUPT6H CDC16 CSNK2B RAB3GAP2 RCL1 USP7 CPSF1 ATP1B3 DNAH5 NUP160	1.49e-07	1425	171	24	30948266
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CUL2 SMARCA5 PDHA1 USP11 DHX40 POLR2B RPS15 LANCL1 PSMD2 TRRAP GDI1 GDI2 NUP205 FASN FAM120A UBR5 CDC16 CSNK2B RCL1 USP7 ASCC3 ATP1B3 NUP160	1.86e-07	1335	171	23	29229926
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	PRPSAP1 FLNB PILRB USP11 POLR2B FASN UBR5 SUPT6H CDC16 CSNK2B RAB3GAP2 OSBPL8 CPNE1 ATP1B3 OGA SPATA4	2.36e-07	670	171	16	22990118
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 FLNC SMARCA5 USP11 ABHD10 ZMYND8 BMS1 TRRAP NUP205 WDR47 UBE4A TGM1 FASN FAM120A UBR5 ZNF644 ADGRL2 NUP160	2.67e-07	857	171	18	25609649
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	CUL2 FLNB FLNC SMARCA5 BMS1 RPS15 KDM3B PTPN23 PSMD2 GDI1 GDI2 ASAP1 NUP205 IWS1 TGM1 FASN UTP18 ANO6 CSNK2B RCL1 CPNE1 ATP1B3 NUP160	2.82e-07	1367	171	23	32687490
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMARCA5 MYCBP2 USP11 POLR2B MED1 TRRAP NUP205 UBR5 SUPT6H CDC16 CSNK2B ASCC3 NUP160	3.15e-07	440	171	13	34244565
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CUL2 MYCBP2 VWA8 PDHA1 USP11 POLR2B BMS1 PREPL UBE4A NBAS GUF1 UTP18 FAM120A UBR5 ANO6 SUPT6H ZNF644 RAB3GAP2 RCL1 OSBPL8 ASCC3 ADGRL2 ATP1B3 OGA	3.21e-07	1487	171	24	33957083
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 IL12RB1 FLNB FLNC PDHA1 MYO9A RBP3 RPS15 NFASC PSMD2 CNKSR2 GDI1 GDI2 CIT ASAP1 WDR47 TGM1 FASN FAM120A RNPEP USP7 OSBPL8 CNTN2	6.23e-07	1431	171	23	37142655
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SMARCA5 POLR2B BMS1 NUP205 UTP18 CSNK2B RCL1 USP7 OSBPL8 ASCC3 NUP160	8.64e-07	332	171	11	25693804
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MYCBP2 VWA8 PDHA1 USP11 ABHD10 POLR2B BMS1 PSMD2 RHOT2 GDI2 PREPL UBE4A NBAS GUF1 UTP18 FAM120A ZNF644 RAB3GAP2 RCL1 FBXO7 OSBPL8 CPSF1 NUP160	1.33e-06	1496	171	23	32877691
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	AVL9 POLR2B ZMYND8 CIT KDM4D FAM120A CDC16 RCL1 OSBPL8 ASCC3	1.45e-06	281	171	10	24163370
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PRPSAP1 CUL2 MYH2 TRAF6 MYCBP2 PDHA1 USP11 POLR2B PSMD2 CNKSR2 TRRAP GDI1 NUP205 UBE4A UBR5 CSNK2B RAB3GAP2 USP7 EDEM1 ATP1B3 NUP160	1.52e-06	1284	171	21	17353931
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	HEXA CUL2 TPP2 FLNB MYCBP2 ENPP1 POLR2B BMS1 KDM3B LANCL1 PTPN23 PSMD2 TRRAP FASN FAM120A RNPEP UBR5 CSNK2B OSBPL8 CERCAM NUP160	1.78e-06	1297	171	21	33545068
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLNC SMARCA5 MYCBP2 VWA8 ABHD10 POLR2B ZMYND8 BMS1 LANCL1 MED1 TRRAP NUP205 IWS1 SUPT6H RCL1 USP7 CPSF1 CPNE1 TNXB	1.79e-06	1082	171	19	38697112
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYCBP2 KDM3B PTPN23 NFASC UBR5 RAB3GAP2 SLIT1 OSBPL8 OGA	1.90e-06	225	171	9	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VWA8 BMS1 KDM3B NFASC G2E3 PREPL NUP205 SUPT6H OSBPL5 CPNE1 EDEM1 ADGRL2 OGA	2.44e-06	529	171	13	14621295
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	TPP2 FLNB FLNC USP11 POLR2B LANCL1 TRRAP FASN UBR5	2.71e-06	235	171	9	30258100
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SMARCA5 MYCBP2 POLR2B KDM3B PTPN23 MED1 TRRAP FASN CDC16 RAB3GAP2 USP7 TAF1 ASCC3	3.65e-06	549	171	13	38280479
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNB FLNC MYCBP2 USP11 POLR2B RPS15 PSMD2 GDI1 GDI2 PREPL FASN FAM120A RNPEP UBR5 CSNK2B RAB3GAP2 USP7 ASCC3 OGA	4.25e-06	1149	171	19	35446349
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB TRAF6 MYCBP2 USP11 ZMYND8 PSMD2 GDI1 CIT PREPL TXNDC11 WDR47 UBE4A GUF1 FAM120A CSNK2B FBXO7 USP7 OSBPL8 CERCAM TAF1	5.76e-06	1285	171	20	35914814
Pubmed	P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.	USP11 TRRAP UBR5 USP7	6.58e-06	25	171	4	36708875
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNB FLNC MYOM1 MYCBP2 USP11 RPS15 PREPL ITGB5 ASAP1 FAM120A SUPT6H TAF1	7.19e-06	497	171	12	23414517
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SMARCA5 VWA8 USP11 POLR2B AOX1 ZMYND8 RHOT2 GPR108 TRRAP FAM120A BRDT UBR5 CDC16 CSNK2B USP7 TAF1 ASCC3 ADGRL2	1.08e-05	1116	171	18	31753913
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	PRPSAP1 SMARCA5 USP11 GDI1 SUPT6H CPSF1 ASCC3 OGA	1.10e-05	212	171	8	33462405
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	FLNC GBP6 MYCBP2 PDHA1 DHX40 ZMYND8 RPS15 LANCL1 PSMD2 GDI2 FASN FAM120A CSNK2B USP7 ASCC3	1.23e-05	809	171	15	32129710
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FLNB SMARCA5 POLR2B BMS1 RPS15 LAMA3 PSMD2 GDI1 CIT NUP205 FASN UTP18 FAM120A CDC16 RCL1 USP7 CPSF1 ASCC3 NUP160	1.50e-05	1257	171	19	36526897
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PRPSAP1 CUL2 MYCBP2 PDHA1 USP11 POLR2B RPS15 PSMD2 RHOT2 GDI2 NUP205 FASN UBR5 FBXO7 USP7 CPSF1 ASCC3 OGA NUP160	1.50e-05	1257	171	19	37317656
Pubmed	Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.	PRPSAP1 MYCBP2 USP11 PSMD2 USP7	1.76e-05	65	171	5	28276505
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	POMT2 ENPP1 LAMA3 ITGB5 CERCAM GALNT6 EDEM1	1.79e-05	164	171	7	32409323
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	SMARCA5 MYCBP2 APOBEC3G IFIT3 FAM120A CAPN7 USP7 ASCC3	1.85e-05	228	171	8	30471916
Pubmed	Defining the membrane proteome of NK cells.	HEXA MYCBP2 RPS15 PSMD2 RHOT2 MED1 CIT NUP205 NBAS FASN FAM120A UBR5 ANO6 OSBPL5 OSBPL8 ASCC3 OGA LMBRD1	1.98e-05	1168	171	18	19946888
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	CUL2 SMARCA5 MED1 USP7	2.07e-05	33	171	4	33567268
Pubmed	Regulation of coenzyme A levels by degradation: the 'Ins and Outs'.	ENPP1 VNN1	2.40e-05	2	171	2	32234503
Pubmed	INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.	OSBPL5 OSBPL8	2.40e-05	2	171	2	26206935
Pubmed	Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy.	LARGE2 LARGE1	2.40e-05	2	171	2	15661757
Pubmed	Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse.	FOXN1 MED1	2.40e-05	2	171	2	20007298
Pubmed	Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.	FOXN1 KL	2.40e-05	2	171	2	30373854
Pubmed	USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast cancer cell migration and invasion.	ZMYND8 USP7	2.40e-05	2	171	2	39128723
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	2.40e-05	2	171	2	9694715
Pubmed	Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.	ADGRL2 ADGRL3	2.40e-05	2	171	2	30792275
Pubmed	LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE.	LARGE2 LARGE1	2.40e-05	2	171	2	23135544
Pubmed	Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.	FOXN1 TRAF6	2.40e-05	2	171	2	23867620
Pubmed	Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.	OSBPL5 OSBPL8	2.40e-05	2	171	2	29748134
Pubmed	Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences.	OR1D2 OR1D5	2.40e-05	2	171	2	1315913
Pubmed	Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies.	LARGE2 LARGE1	2.40e-05	2	171	2	15958417
Pubmed	PILRα and PILRβ have a siglec fold and provide the basis of binding to sialic acid.	PILRB PILRA	2.40e-05	2	171	2	24843130
Pubmed	Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.	IWS1 SUPT6H	2.40e-05	2	171	2	30208029
Pubmed	ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.	OSBPL5 OSBPL8	2.40e-05	2	171	2	27113756
Pubmed	E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.	UBR5 OGA	2.40e-05	2	171	2	38755129
Pubmed	Latrophilin GPCR signaling mediates synapse formation.	ADGRL2 ADGRL3	2.40e-05	2	171	2	33646123
Pubmed	Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.	GDI1 GDI2	2.40e-05	2	171	2	7585614
Pubmed	A single-amino-acid substitution in herpes simplex virus 1 envelope glycoprotein B at a site required for binding to the paired immunoglobulin-like type 2 receptor alpha (PILRalpha) abrogates PILRalpha-dependent viral entry and reduces pathogenesis.	PILRB PILRA	2.40e-05	2	171	2	20686018
Pubmed	Differences in CD75s- and iso-CD75s-ganglioside content and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in human hepatocellular carcinomas and nontumoral liver tissues.	ST6GAL1 ST3GAL6	2.40e-05	2	171	2	21147760
Pubmed	USP7 attenuates endoplasmic reticulum stress-induced apoptotic cell death through deubiquitination and stabilization of FBXO7.	FBXO7 USP7	2.40e-05	2	171	2	37874827
Pubmed	LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE.	LARGE2 LARGE1	2.40e-05	2	171	2	15752776
Pubmed	Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy.	LARGE2 LARGE1	2.40e-05	2	171	2	12417403
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	2.40e-05	2	171	2	12525170
Pubmed	Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation.	PILRB PILRA	2.40e-05	2	171	2	23142774
Pubmed	Modulation of paired immunoglobulin-like type 2 receptor signaling alters the host response to Staphylococcus aureus-induced pneumonia.	PILRB PILRA	2.40e-05	2	171	2	20065029
Pubmed	Stability and function of RCL1 are dependent on the interaction with BMS1.	BMS1 RCL1	2.40e-05	2	171	2	37451810
Pubmed	PILRα negatively regulates mouse inflammatory arthritis.	PILRB PILRA	2.40e-05	2	171	2	24935926
Pubmed	The Ig-like v-type domain of paired Ig-like type 2 receptor alpha is critical for herpes simplex virus type 1-mediated membrane fusion.	PILRB PILRA	2.40e-05	2	171	2	20573830
Pubmed	ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.	OSBPL5 OSBPL8	2.40e-05	2	171	2	28970484
Pubmed	Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation.	ENPP1 ACE	2.40e-05	2	171	2	17367703
Pubmed	Monocyte infiltration into obese and fibrilized tissues is regulated by PILRα.	PILRB PILRA	2.40e-05	2	171	2	26840635
Pubmed	Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2.	LARGE2 LARGE1	2.40e-05	2	171	2	23125099
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	POLR2B PSMD2 RHOT2 NUP205 FASN CSNK2B CPSF1 ASCC3	2.45e-05	237	171	8	29564676
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	USP11 DHX40 TRRAP UBR5 ZNF644 USP7	2.46e-05	116	171	6	30804394
Pubmed	AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.	POMT2 LARGE2 LARGE1	2.49e-05	12	171	3	24256719
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	CUL2 FLNB POLR2B BMS1 RPS15 GJC1 PSMD2 GDI2 IWS1 FASN FAM120A UBR5 CDC16 USP7 OSBPL8 CPSF1	2.65e-05	971	171	16	33306668
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	HEXA POMT2 LARGE2 TPST2 MYCBP2 ENPP1 SLC38A5 LANCL1 PSMD2 TMTC2 ST6GAL1 ITGB5 TXNDC11 ANO6 CPSF1 CERCAM EDEM1 ATP1B3	2.86e-05	1201	171	18	35696571
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SMARCA5 PDHA1 POLR2B ZMYND8 BMS1 RPS15 KDM3B PSMD2 NUP205 GUF1 FASN UTP18 FAM120A CSNK2B RCL1 FBXO7 OSBPL8 ASCC3 NUP160	2.88e-05	1318	171	19	30463901
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	CUL2 VWA8 POLR2B TRRAP FASN CPSF1	2.97e-05	120	171	6	27320910
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	FLNB FLNC ENPP1 PSMD2 GDI2 NUP205 FASN USP7 ASCC3 ATP1B3 NUP160	3.03e-05	484	171	11	31995728
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	PDHA1 POLR2B PSMD2 MED1 TRRAP GDI1 PREPL ITGB5 NUP205 IWS1 UBE4A NBAS FASN UBR5 CDC16 RAB3GAP2 USP7 CPSF1 OGA	3.15e-05	1327	171	19	32694731
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCA5 MYCBP2 PDHA1 ZMYND8 KDM3B MED1 TRRAP IWS1 FASN UTP18 ZNF644 USP7 CPSF1 OGA	3.17e-05	774	171	14	15302935
Pubmed	Identification and Characterization of USP7 Targets in Cancer Cells.	USP11 DHX40 USP7	3.22e-05	13	171	3	30367141
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	FLNB FLNC SMARCA5 PDHA1 DHX40 BMS1 RPS15 PSMD2 RHOT2 NUP205 FASN UTP18 SUPT6H CSNK2B RCL1 USP7	3.30e-05	989	171	16	36424410
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AVL9 CNKSR2 ASAP1 WDR47 UBR5 ZNF644 RAB3GAP2 SLIT1 ADGRL3 LARGE1	3.66e-05	407	171	10	12693553
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	FLNC PDHA1 BMS1 RPS15 PSMD2 FASN UBR5 OSBPL8 ATP1B3 NUP160	3.73e-05	408	171	10	33766124
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	FLNC MYCBP2 USP11 TRRAP UBR5	3.78e-05	76	171	5	27542412
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	CUL2 USP11 RPS15 LANCL1 PTPN23 MED1 UBR5 RAB3GAP2 USP7 OSBPL8 CPSF1 ASCC3	4.86e-05	604	171	12	38803224
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	BMS1 FAM120A SUPT6H NUP160	4.96e-05	41	171	4	8724849
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	PDHA1 PSMD2 NUP205 FASN FAM120A UBR5 ZBTB25 CDC16	4.97e-05	262	171	8	36880596
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNB FLNC SMARCA5 MYCBP2 POLR2B PSMD2 TRRAP CIT NUP205 FASN UBR5 SUPT6H CSNK2B CPSF1 ASCC3 NUP160	4.98e-05	1024	171	16	24711643
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ZMYND8 KDM3B MED1 TRRAP USP7 OGA	5.52e-05	134	171	6	25452129
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	HEXA FLNB FLNC PSMD2 TRRAP GDI1 FASN FAM120A USP7	5.58e-05	344	171	9	30333137
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	USP11 POLR2B TGM1 FASN UBR5	6.11e-05	84	171	5	29563501
Pubmed	Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.	OR1D4 OR1D2 OR1D5	6.24e-05	16	171	3	10673334
Interaction	SIRT7 interactions	TPP2 FLNB FLNC MYCBP2 PDHA1 USP11 BMS1 RPS15 PSMD2 TRRAP GDI1 GDI2 NUP205 FASN UTP18 FAM120A RNPEP UBR5 SUPT6H RCL1 USP7 OSBPL8 CPSF1 ASCC3 NUP160	9.06e-10	744	159	25	int:SIRT7
Interaction	SIRT6 interactions	FLNB SMARCA5 MYCBP2 USP11 POLR2B PSMD2 MED1 TRRAP HPS3 NUP205 UBR5 SUPT6H CDC16 ZNF644 CSNK2B USP7 ASCC3 EDEM1 NUP160	5.63e-07	628	159	19	int:SIRT6
Interaction	BAGE2 interactions	LARGE2 ENPP1 LAMA3 ST3GAL6 GALNT6 LARGE1	1.90e-05	70	159	6	int:BAGE2
Interaction	DHX40 interactions	USP11 DHX40 BMS1 BRDT UBR5 SUPT6H ZNF644 FBXO7 USP7 TAF1	2.95e-05	249	159	10	int:DHX40
Interaction	C9orf78 interactions	HEXA CUL2 SMARCA5 VWA8 USP11 POLR2B ZMYND8 PSMD2 UBE4A UTP18 RNPEP SUPT6H CDC16 RAB3GAP2 OSBPL8 NUP160	3.31e-05	620	159	16	int:C9orf78
Interaction	CEACAM8 interactions	LARGE2 LAMA3 ITGB5 TXNDC11 GUF1 CERCAM LARGE1	4.46e-05	119	159	7	int:CEACAM8
Interaction	RBM3 interactions	CUL2 RBP3 MAB21L2 TRRAP CIT FAM120A USP7 AP1G2	4.65e-05	163	159	8	int:RBM3
Interaction	OR1M1 interactions	NBAS OSBPL5 OSBPL8 EDEM1	4.87e-05	26	159	4	int:OR1M1
Interaction	FOXI2 interactions	USP11 NUP205 UBE4A FASN NUP160	6.07e-05	53	159	5	int:FOXI2
Interaction	TAF5 interactions	TRRAP CIT BRDT CDC16 CPSF1 TAF1	6.13e-05	86	159	6	int:TAF5
Interaction	OR1D2 interactions	CIT OR1D2	6.19e-05	2	159	2	int:OR1D2
Interaction	CIT interactions	FLNB FLNC SMARCA5 VWA8 PDHA1 POLR2B ZMYND8 BMS1 RPS15 LANCL1 PSMD2 MED1 TRRAP CIT TXNDC11 NUP205 IWS1 OR1D2 NBAS FASN UTP18 FAM120A SUPT6H RCL1 CPSF1 NUP160	6.76e-05	1450	159	26	int:CIT
GeneFamily	Adhesion G protein-coupled receptors, subfamily L	ADGRL2 ADGRL3	2.14e-04	4	109	2	918
GeneFamily	Fibronectin type III domain containing	IL12RB1 IL31RA MYOM1 NFASC TNXB CNTN2	4.18e-04	160	109	6	555
GeneFamily	Glycosyltransferase family 8	LARGE2 LARGE1	1.26e-03	9	109	2	436
GeneFamily	Olfactory receptors, family 1	OR1D4 OR1D2 OR1D5	1.79e-03	40	109	3	147
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL5 OSBPL8	2.28e-03	12	109	2	670
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CUL2 FLNB SMARCA5 MYCBP2 AVL9 POLR2B ZMYND8 KDM3B MED1 TRRAP ADGRG6 NBAS UTP18 UBR5 CDC16 USP7 OSBPL8 ASCC3 NUP160	2.25e-06	856	166	19	M4500
Coexpression	GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP	HEXA GBP6 MYOM1 PILRA ENPP1 LAMA3 ADGRG6 TGM1 GALNT6	5.09e-06	198	166	9	M9778
CoexpressionAtlas	gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3	IL12RB1 TPST2 PILRB PILRA MYO9A AOAH ITGB5 TGM1 CD6 SH2D1B FCN1 ATP1B3 ADGRL3	8.63e-06	393	159	13	GSM476672_500
ToppCell	COVID-19_Moderate-NK_activated\|COVID-19_Moderate / disease group, cell group and cell class	TPST2 MGAM AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 CERCAM IFI6	4.96e-08	189	170	9	8f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STAB2 CYP7A1 CNKSR2 MYO15A DNAH5 ADGRL3 CNTN2	5.59e-07	184	170	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 NPSR1 ST6GAL1 TXNDC11 ENAM NBAS EDEM1 ADGRL2	5.59e-07	184	170	8	42cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STAB2 CYP7A1 CNKSR2 MYO15A DNAH5 ADGRL3 CNTN2	5.59e-07	184	170	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STAB2 CYP7A1 CNKSR2 MYO15A DNAH5 ADGRL3 CNTN2	5.59e-07	184	170	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	ASK440-Immune-NK_cell\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	IL12RB1 TPST2 AOAH APOBEC3G PKDREJ SH2D1B OSBPL5	6.06e-06	180	170	7	340e750356d23fe9af0e8f298f8a273ff426052f
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	NBEAL1 LANCL1 MED1 IWS1 UBE4A ZNF644 TAF1	7.51e-06	186	170	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRPSAP1 FLNB EPB41L4A ACE EXOC3L1 ADGRL2 ADGRL3	9.88e-06	194	170	7	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS-IL1RA-Endothelial-Epi-like-Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TPST2 PTPN23 ACE KL GJC3 FER1L5	1.52e-05	138	170	6	5f8ac8f67e34a7cf560099208e6884102532391e
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	AOX1 ENAM TGM1 FASN SLC4A9 ADGRL3	2.25e-05	148	170	6	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FLNC IL31RA ENPP1 AOX1 KL TNXB	2.82e-05	154	170	6	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF6 AVL9 RHOT2 ACE ITGB5 LMBRD1	4.01e-05	164	170	6	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	droplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 ST6GAL1 TXNDC11 KDM4D SLIT1 ADGRL2	4.15e-05	165	170	6	21a82a975f550080b6674750b06212205cd16742
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP1 ESX1 ST6GAL1 TXNDC11 NBAS EDEM1	4.29e-05	166	170	6	139bf49eb3624d9eec7e8a2cb33d69716d63a7c5
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP1 ESX1 ST6GAL1 TXNDC11 NBAS EDEM1	4.29e-05	166	170	6	85f59c3cc7db8863ec0044f1fcc14580834f830b
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 ESX1 ST6GAL1 TXNDC11 NBAS EDEM1	4.58e-05	168	170	6	41da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 ESX1 ST6GAL1 TXNDC11 NBAS EDEM1	4.58e-05	168	170	6	a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TPST2 TMTC2 ACE ST3GAL6 EDEM1 ADGRL2	4.74e-05	169	170	6	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TPST2 TMTC2 ACE ST3GAL6 EDEM1 ADGRL2	4.74e-05	169	170	6	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 VWA8 ENPP1 WDR47 RNPEP BRDT	5.06e-05	171	170	6	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBX15 MGAM FLNC AOX1 MAB21L2 TNXB	5.57e-05	174	170	6	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-E\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ENPP1 ACE IFIT3 KL ADGRL2 ADGRL3	5.57e-05	174	170	6	4a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 GBP6 NBEAL1 NUP210L IFIT3 ASCC3	6.32e-05	178	170	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	normal_Lymph_Node-Myeloid_cells-CD141+_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	ENPP1 AOAH CYP2S1 TM6SF1 ASAP1 ADGRG6	6.52e-05	179	170	6	ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEXA PILRA MYO9A AOAH ITGB5 ANO6	6.93e-05	181	170	6	a93df1ba23d5b5f249491d69d12bfc0e274dafcf
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	NBEAL1 GJC1 LAMA3 NFASC ASAP1 ADGRL3	6.93e-05	181	170	6	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	GABBR2 EPB41L4A ACE CFAP161 ADGRL2 ADGRL3	6.93e-05	181	170	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX15 PILRA SERINC4 CERCAM TNXB	7.03e-05	112	170	5	88fcd0dc12b5c00804381fb7dd59a6a2a9f37419
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX15 PILRA SERINC4 CERCAM TNXB	7.03e-05	112	170	5	fd4cc5190626cb262aae0a7f04559b0e9757270e
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX15 PILRA SERINC4 CERCAM TNXB	7.03e-05	112	170	5	d652e6fae433a6b56bf2a448fba2cf6c5e558905
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FLNC MYOM1 GJC1 NFASC SLIT1 ADGRL3	7.15e-05	182	170	6	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	facs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POMT2 ENPP1 DHX40 TXNDC11 NBAS EDEM1	7.37e-05	183	170	6	b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	GJC1 NFASC ADGRG6 FGF14 ADGRL2 LARGE1	7.82e-05	185	170	6	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	PDE1A NBEAL1 GJC1 NFASC ASAP1 ADGRL3	7.82e-05	185	170	6	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH2 NFASC MAB21L2 FGF14 GJC3 CDH8	8.06e-05	186	170	6	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	COVID-19_Moderate-NK_activated\|World / disease group, cell group and cell class	MGAM APOBEC3G IFIT3 SH2D1B CERCAM IFI6	8.06e-05	186	170	6	ff8f32f69516bf785224fa12f8139a95359b0279
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	FLNB PDE1A ST6GAL1 EPB41L4A ASAP1 ADGRG6	8.80e-05	189	170	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	FLNB PDE1A ST6GAL1 EPB41L4A ASAP1 ADGRG6	8.80e-05	189	170	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	FOXN1 TPST2 GBP6 PGLYRP3 TGM1 ATP1B3	8.80e-05	189	170	6	533c302df467d13ab639232daf4f8cafb808260b
ToppCell	B_cells-Plasmablasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TPST2 SLC38A5 ST6GAL1 TXNDC11 ENAM EDEM1	8.80e-05	189	170	6	87cb7b6ba9fd57100d68e6eaeecd1ac6ab22d1c6
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	PDE1A GJC1 NFASC EPB41L4A OSBPL5 ADGRL3	9.32e-05	191	170	6	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	normal_Pleural_Fluid-T/NK_cells-NK\|normal_Pleural_Fluid / Location, Cell class and cell subclass	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	9.59e-05	192	170	6	59dd4f5ae9f1cca78adf60b71661092ef09e6641
ToppCell	MS-NK-\|MS / Condition, Cell_class and T cell subcluster	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	9.59e-05	192	170	6	f97f5f8226f5c65ca93072ef35d753231bee2490
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TPST2 TMTC2 EPB41L4A ADGRG6 EXOC3L1 ADGRL3	9.59e-05	192	170	6	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	MS-NK\|MS / Condition, Cell_class and T cell subcluster	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	9.59e-05	192	170	6	f44f5dd30db169fdd16c9d706d17ad44907a17af
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NFASC NOX4 EPB41L4A ADGRG6 ADGRL2 LARGE1	9.59e-05	192	170	6	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX15 ENPP1 ST6GAL1 TXNDC11 EDEM1 ADGRL2	9.59e-05	192	170	6	6417468829517a0f6e04e7e44eec1622001d4c5c
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	TPST2 FLNB ST6GAL1 EPB41L4A ASAP1 ADGRG6	9.87e-05	193	170	6	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	9.87e-05	193	170	6	e325cf49e159c6be205ed93adaa09efdd0c122b4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFASC FBXO7 GJC3 GALNT6 ATP1B3 CNTN2	9.87e-05	193	170	6	4274c95cedad2ae8c6693ad00deda2b1ba5b5682
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	SMARCA5 AVL9 NBEAL1 G2E3 MED1 FAM120A	9.87e-05	193	170	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	GABBR2 EPB41L4A EXOC3L1 CFAP161 ADGRL2 ADGRL3	9.87e-05	193	170	6	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	Leuk-UTI\|World / Disease, Lineage and Cell Type	PILRA NBEAL1 IFIT3 FCN1 EXOC3L1 IFI6	9.87e-05	193	170	6	26119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FLNC ENPP1 NOX4 KL TNXB	1.01e-04	121	170	5	5035e071033cb76a7fc0128716755b14821e8f05
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FLNC ENPP1 NOX4 KL TNXB	1.01e-04	121	170	5	c96115bd33455296378a257583b49442d00b39ca
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L4A ACE IFIT3 EXOC3L1 ADGRL2 ADGRL3	1.02e-04	194	170	6	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L4A ACE IFIT3 EXOC3L1 ADGRL2 ADGRL3	1.02e-04	194	170	6	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L4A ACE IFIT3 EXOC3L1 ADGRL2 ADGRL3	1.02e-04	194	170	6	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TPST2 APOBEC3G SH2D1B OSBPL5 CERCAM IFI6	1.02e-04	194	170	6	a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TPST2 APOBEC3G SH2D1B OSBPL5 CERCAM IFI6	1.02e-04	194	170	6	0abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L4A ACE IFIT3 EXOC3L1 ADGRL2 ADGRL3	1.02e-04	194	170	6	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	BLOOD--(0)_NK_cells_(CD56bright-like)\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	1.02e-04	194	170	6	8d4368d546bba17a420e172bfb5f1f337fe23c44
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPST2 AOAH APOBEC3G IFIT3 SH2D1B OSBPL5	1.02e-04	194	170	6	52e09b14159b609af00264a8f38accf37ba8f464
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PILRB AOAH APOBEC3G CD6 SH2D1B OSBPL5	1.04e-04	195	170	6	e1b7ef4ba2ab14d3c839b6305d91efcfd0826220
ToppCell	3'-Distal_airway-Immune_Lymphocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PILRB AOAH APOBEC3G CD6 SH2D1B OSBPL5	1.04e-04	195	170	6	4a60b51f92830882872f2fe1a911db2970faf071
ToppCell	Bronchial_Biopsy-Immune-Luminal_Macrophages\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	HEXA PILRA ACE IFIT3 UTP18 IFI6	1.04e-04	195	170	6	6800c17026ec6c56132bf4664b8fcd74d7836579
ToppCell	356C\|World / Donor, Lineage, Cell class and subclass (all cells)	TPST2 AOAH SH2D1B FCN1 ATP1B3 IFI6	1.04e-04	195	170	6	b19609f519188cf27859cbdc014e65fc38e24391
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	PILRA AOAH HPS3 FCN1 VNN1 ATP1B3	1.04e-04	195	170	6	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	IL31RA CYP7A1 ENPP1 KL TNXB	1.09e-04	123	170	5	28be15b759c152662b29c323b1cc3f02f7830dbe
ToppCell	Severe-Plasmablast\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TPST2 SLC38A5 ST6GAL1 TXNDC11 EDEM1 IFI6	1.10e-04	197	170	6	1089aa7991812378668d0f3d57f8000e6245a713
ToppCell	BLOOD--(0)_NK_cells_(CD56dim-like)\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	1.10e-04	197	170	6	4c15b3386b89191af9332738e597549e2305de26
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB1 TPST2 APOBEC3G SH2D1B OSBPL5 CERCAM	1.10e-04	197	170	6	76304df40f87224f8e415677e3ee8fb183fe0c03
ToppCell	356C-Lymphocytic-NK_cells\|356C / Donor, Lineage, Cell class and subclass (all cells)	IL12RB1 TPST2 AOAH APOBEC3G SH2D1B OSBPL5	1.10e-04	197	170	6	ae55ac5c714e55061d605dee030cbe29b43cf9c1
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TPST2 EPB41L4A TM6SF1 ASAP1 ADGRG6 ADGRL2	1.10e-04	197	170	6	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	BLOOD--(0)_NK_cell\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	1.10e-04	197	170	6	ce35c3ba6db897235d0107fa7dadc5013bf4da24
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC MYOM1 GJC1 NFASC FGF14 ADGRL3	1.10e-04	197	170	6	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	COVID-19_Severe-NK\|COVID-19_Severe / Disease condition and Cell class	TPST2 AOAH APOBEC3G SH2D1B OSBPL5 CERCAM	1.14e-04	198	170	6	742c4d6016cfa48444a5919a885ab8d02cad7e18
ToppCell	mild-Lymphocytic-NK_cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TPST2 AOAH APOBEC3G SH2D1B OSBPL5 CERCAM	1.14e-04	198	170	6	1d20fc9948965de52a98f758035edfdd12cafc5f
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1A MYOM1 GJC1 NFASC PGLYRP3 ATP1B3	1.14e-04	198	170	6	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	(0)_NK_cells\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	1.14e-04	198	170	6	c91c3ccba118dffb12c0bf8036f51fc76f0e305d
ToppCell	Transverse-T_cell-CD8_T\|T_cell / Region, Cell class and subclass	TPST2 USP11 AOAH APOBEC3G DPP8 ATP1B3	1.14e-04	198	170	6	3b0613171cc7d5320f0b525cc6836f21874b0505
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.14e-04	198	170	6	0e918e9db9b884f5328d438e90efe065e27266ee
ToppCell	Multiple_Sclerosis-Myeloid-cDC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	PILRA AOAH CYP2S1 ADGRG6 ST3GAL6 FCN1	1.14e-04	198	170	6	ac139bfbf52b2feddb0c05b0708c8c9efbe119c9
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-NK\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TPST2 PILRB AOAH APOBEC3G SH2D1B OSBPL5	1.14e-04	198	170	6	d413020012977eb8da0a5641dd16d0b0a60bec38
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.14e-04	198	170	6	ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.14e-04	198	170	6	fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC MYOM1 GJC1 NFASC FGF14 ADGRL3	1.14e-04	198	170	6	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.14e-04	198	170	6	1ef3a6bd681c223eed58300348adfef89df5563c
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TBX15 PDE1A ENPP1 NOX4 CERCAM TNXB	1.17e-04	199	170	6	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB SLC38A5 NOX4 ACE KL ADGRL2	1.17e-04	199	170	6	63c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCell	COVID-19_Severe-Lymphoid_T/NK-NK_activated\|COVID-19_Severe / Disease group, lineage and cell class	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.17e-04	199	170	6	edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCell	COVID-19_Moderate-NK\|COVID-19_Moderate / disease group, cell group and cell class	TPST2 AOAH APOBEC3G SH2D1B OSBPL5 CERCAM	1.17e-04	199	170	6	e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MYCBP2 CNKSR2 GABBR2 PREPL FGF14 ADGRL2	1.20e-04	200	170	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE1A LANCL1 NFASC TMTC2 CERCAM CNTN2	1.20e-04	200	170	6	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE1A LANCL1 NFASC TMTC2 CERCAM CNTN2	1.20e-04	200	170	6	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	COVID-19_Severe-NK_activated\|COVID-19_Severe / Disease condition and Cell class	AOAH APOBEC3G IFIT3 SH2D1B OSBPL5 IFI6	1.20e-04	200	170	6	f1f6c7f7f75f891c9ccf6bf58f4d65b9cf10bbd8
ToppCell	mild-CD163+_Monocytes_(Sample_ID1_d7)\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PILRA IFIT3 TGM1 FCN1 EXOC3L1 IFI6	1.20e-04	200	170	6	82126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-NK\|Leuk-UTI / Disease, condition lineage and cell class	TPST2 PILRB APOBEC3G SH2D1B OSBPL5 CERCAM	1.20e-04	200	170	6	bb37fed4872e71f413ae7c4aa12586fa31075334
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPB41L4A ACE KL CFAP161 ADGRL2 ADGRL3	1.20e-04	200	170	6	105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE1A LANCL1 NFASC TMTC2 CERCAM CNTN2	1.20e-04	200	170	6	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
Disease	glomerular filtration rate, renal transplant outcome measurement	OR1D4 NBAS OR1D5 ADGRL2	4.52e-05	35	167	4	EFO_0005199, EFO_0005208
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	9.52e-05	3	167	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	9.52e-05	3	167	2	DOID:0111190 (implicated_via_orthology)
Disease	MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 1	POMT2 LARGE1	3.15e-04	5	167	2	236670
Disease	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1	POMT2 LARGE1	3.15e-04	5	167	2	cv:C4284790
Disease	Ectodermal Dysplasia	DHX40 BMS1	4.71e-04	6	167	2	C0013575
Disease	laryngeal carcinoma (is_marker_for)	TRAF6 UBR5	4.71e-04	6	167	2	DOID:2600 (is_marker_for)
Disease	contactin-2 measurement	NFASC CNTN2	4.71e-04	6	167	2	EFO_0008100
Disease	Qualitative or quantitative defects of alpha-dystroglycan	POMT2 LARGE1	4.71e-04	6	167	2	cv:C2936406
Disease	Amelogenesis imperfecta local hypoplastic form	LAMA3 ENAM	6.56e-04	7	167	2	C0399367
Disease	renin measurement	NBEAL1 CNTN2	8.72e-04	8	167	2	EFO_0010616
Disease	Intellectual Disability	HEXA KDM3B PTPN23 TRRAP PREPL FASN TAF1 ASCC3 LARGE1	1.06e-03	447	167	9	C3714756
Disease	response to methylphenidate	ST6GAL1 FGF14	1.12e-03	9	167	2	GO_0036271
Disease	revision of total hip arthroplasty, aseptic loosening	GABBR2 EPB41L4A OSBPL5	1.74e-03	42	167	3	EFO_0010725, EFO_0020973
Disease	Congenital muscular dystrophy	POMT2 LARGE1	2.02e-03	12	167	2	cv:C0699743
Disease	middle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement	MYCBP2 CNKSR2	2.38e-03	13	167	2	EFO_0006514, EFO_0010316
Disease	myopathy (implicated_via_orthology)	MYH2 FLNB FLNC	2.55e-03	48	167	3	DOID:423 (implicated_via_orthology)
Disease	Kidney Failure, Chronic	NOX4 ACE FASN	2.55e-03	48	167	3	C0022661
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	POMT2 LARGE1	2.77e-03	14	167	2	C1836373
Disease	alpha-Dystroglycanopathies	POMT2 LARGE1	2.77e-03	14	167	2	C2936406
Disease	Fukuyama Type Congenital Muscular Dystrophy	POMT2 LARGE1	2.77e-03	14	167	2	C0410174
Disease	Muscle eye brain disease	POMT2 LARGE1	2.77e-03	14	167	2	C0457133
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	POMT2 LARGE1	2.77e-03	14	167	2	C4284790
Disease	Walker-Warburg congenital muscular dystrophy	POMT2 LARGE1	3.19e-03	15	167	2	C0265221
Disease	myopia (is_implicated_in)	ZNF644 CPSF1	3.63e-03	16	167	2	DOID:11830 (is_implicated_in)
Disease	thyroid volume	FAM227B DNAH5	3.63e-03	16	167	2	EFO_0004865
Disease	partial epilepsy	SMARCA5 ADGRL3	4.10e-03	17	167	2	EFO_0004263
Disease	Renal Insufficiency	NOX4 ACE	4.10e-03	17	167	2	C1565489
Disease	non-alcoholic steatohepatitis (biomarker_via_orthology)	CYP7A1 NOX4	4.10e-03	17	167	2	DOID:0080547 (biomarker_via_orthology)
Disease	cognitive function measurement, self reported educational attainment	MYCBP2 DPP8 FAM120A OGA TNXB CDH8 NUP160	4.22e-03	355	167	7	EFO_0004784, EFO_0008354
Disease	sleep duration	MYCBP2 KDM3B CNKSR2 ASAP1 UPP2 LMBRD1 NUP160	4.69e-03	362	167	7	EFO_0005271
Disease	neuroticism measurement, cognitive function measurement	TPST2 PDE1A NBEAL1 NUP210L FAM120A RAB40C CPNE1 ASCC3 OGA	5.11e-03	566	167	9	EFO_0007660, EFO_0008354
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A PREPL	5.11e-03	19	167	2	C0751884
Disease	inflammatory bowel disease (is_implicated_in)	NPSR1 ANO6	5.11e-03	19	167	2	DOID:0050589 (is_implicated_in)
Disease	ankylosing spondylitis (is_implicated_in)	ACE ANO6	5.11e-03	19	167	2	DOID:7147 (is_implicated_in)
Disease	lysophosphatidylcholine measurement	MGAM CD6 FGF14	5.27e-03	62	167	3	EFO_0010224

Protein segments in the cluster

Peptide	Gene	Start	Entry
NFGGQSPLILYYLKM	FAM227B	386	Q96M60
YYLKMHELAGISKAP	FAM227B	396	Q96M60
RGKSMAPHYVPYLLA	EXOC3L1	476	Q86VI1
LAHPLDMFLGGAYYA	ESX1	211	Q8N693
YDAVGKMLNLTHTYP	SLC4A9	541	Q96Q91
NVTMGYKYPPLCLGH	ERVK11-1	21	P61568
QKYTLPLYHAMMGGS	RNPEP	601	Q9H4A4
GHIQYFMQYKDLPVA	ACE	991	P12821
LHNYYDVVKNPMDLG	BRDT	306	Q58F21
NNLPKYYILLHIMLG	APOBEC3G	176	Q9HC16
QLGHCLAMEEPKGYY	ADGRG6	521	Q86SQ4
VYYKSMPNLGSRNHV	ADGRL3	1391	Q9HAR2
LAKLLYVHMLGYPAH	AP1G2	51	O75843
YYKSMPNLGAGHQLQ	ADGRL2	1406	O95490
DGYIHYGDKVMLVNP	CFAP161	61	Q6P656
YPGAKLFYLSGMVHG	BMS1	211	Q14692
DKNHLYLVMEYQPGG	CIT	166	O14578
DMLITGGRHPYLGKY	AOX1	841	Q06278
MADLPGNILLYYTAK	NBEAL1	821	Q6ZS30
PDIYIYTDHMKGVNS	RCL1	221	Q9Y2P8
MGSQGSPVKSYDYLL	RAB40C	1	Q96S21
TLKHSGIGRAVMYLY	IWS1	651	Q96ST2
PNKHYSGLYGLMKLV	LARGE2	171	Q8N3Y3
YLGQLHYLQSRVPMG	PTPN23	71	Q9H3S7
HKLYAGQVGYLIAGM	GUF1	311	Q8N442
IPASHNKYYMLVARG	MFSD8	126	Q8NHS3
IAYKPPGFSLMYHLL	NUP205	796	Q92621
RYHPLGQLNKDMTYA	AOAH	431	P28039
QDYHLQPMGKLGLFY	ANO6	651	Q4KMQ2
KGLPHSLSGRMYYSC	CD6	316	P30203
VGKHCRLLYPGYKIM	RAB3GAP2	491	Q9H2M9
ALGLQYHLYGFQMPS	GJC3	151	Q8NFK1
LYPNIMTGHLYAKLV	OR11H2	146	Q8NH07
PMKTIAYGGCLVHLY	OR2G2	91	Q8NGZ5
NGKKVLHMDRNPYYG	GDI2	26	P50395
LSAIYGGTYMLNKPI	GDI2	241	P50395
GQYLASLMHYDPKLE	KLHL33	381	A6NCF5
IPNKHYSGIYGLMKL	LARGE1	211	O95461
DRSKPLPYGHYSMQK	LEXM	241	Q3ZCV2
IFKSPQTYMDGLLHY	LAMA3	2836	Q16787
CHGAPGVIYMLIQAY	LANCL1	276	O43813
RYHAIVYPMKFLQGE	NPSR1	146	Q6W5P4
MLHDKVGEPYSIQAY	IL31RA	401	Q8NI17
TMHYNQVLPDYLKGL	MYO15A	3311	Q9UKN7
YTAYGMSALPLNLIK	LMBRD1	211	Q9NUN5
HMVLNKTYGSYLGVN	AQP7B	61	A0A075B734
LPYLYTLMQKAHTEG	MGAM	1616	O43451
MYAVYKQAHPPTGLE	CPSF1	1	Q10570
VGYTLLLLMKYPHVQ	CYP2S1	311	Q96SQ9
KYMGSHIPESPLQFY	FLNB	1801	O75369
SIYKLTGAVMHYGNL	MYH2	351	Q9UKX2
RKTYHMVGLAYPAAV	PDE1A	136	P54750
YLTPNYLLMGHSDVV	PGLYRP3	306	Q96LB9
YAPTEKGLHQMGIKY	FLNC	1826	Q14315
YYLQMHPDGALDGTK	FGF14	81	Q92915
KMGIYGSVPYLLAHK	GANC	261	Q8TET4
RGLASMNNLYTPYHK	ONECUT1	156	Q9UBC0
YTMIGTHENPGLYAL	KIF24	321	Q5T7B8
LGPKMYNAYGLITAE	KDM3B	1536	Q7LBC6
MDLYSINYLHLGEPK	KDM4D	196	Q6B0I6
LYRTGKSYLMNHLAG	GBP6	46	Q6ZN66
GLYPESHGIIDNKMY	ENPP1	266	P22413
GLMYPYIFHVLTKGE	FAM120A	566	Q9NZB2
HYMLYKNFTALIPGT	ITGB5	341	P18084
QHMVKYIYPTIGGFD	NBAS	1741	A2RRP1
PEYHYLHQMLGLGLC	NOX4	41	Q9NPH5
PYAHCKGILYGTMTL	OSBPL8	571	Q9BZF1
SNLNGLYLMGPHESY	FCN1	286	O00602
LYLMGPHESYANGIN	FCN1	291	O00602
EHPNGIMIGYTLKYV	NFASC	956	O94856
YLYGVTQPKHLSASM	PILRA	31	Q9UKJ1
YYEAGKMLAISLVHG	G2E3	446	Q7L622
GCHLPMLYIGLEYGL	CDC16	366	Q13042
YNPCGKYMVKLHLNG	CAPN7	326	Q9Y6W3
SGVYKLQYMHPLCEG	FBXO7	231	Q9Y3I1
TPSVMYLGYAIHKIA	GJC1	86	P36383
PLIMYSCHGLGGNQY	GALNT6	521	Q8NCL4
YGMPLAIFTKGYLCL	AVL9	396	Q8NBF6
TTGFTLYGMLYKPHD	DPP8	641	Q6V1X1
IGALMGYATHKYLDS	IFI6	111	P09912
ATMYNLLAYIKHLDG	IFIT3	51	O14879
LHYLCTGEVKMNYLG	CUL2	556	Q13617
LGNTVLHYCSMYSKP	ASAP1	636	Q9ULH1
GYKMLYQNDLHLTPT	CNTN2	946	Q02246
RLYGFKIHPMAYQLQ	CSNK2B	186	P67870
LYQATKNPFYLHVGM	EDEM1	501	Q92611
GQPLNNYHMKTLLLY	MAB21L2	266	Q9Y586
LHLGKMPYLSGAAYN	IL12RB1	301	P42701
LQVFHKRAIMPYGVY	ATE1	471	O95260
AFYDAIKYGPNHLMV	GABBR2	116	O75899
FKYGDLPMYIISNGI	KL	861	Q9UEF7
GAYKIYVMATHGILS	PRPSAP1	276	Q14558
LMGKYVHFITNPLSY	CYP7A1	71	P22680
NGKKVLHMDRNPYYG	GDI1	26	P31150
LSAIYGGTYMLNKPV	GDI1	241	P31150
VNKSNYKLPHSEGYM	ENAM	466	Q9NRM1
KNGHYFLYSLLPEMV	CDH8	526	P55286
RYGYMNVPVKSHQGL	CERCAM	266	Q5T4B2
EQYTPKAKYHGNVML	FASN	2431	P49327
LPKYLYEAGFSQHGM	DHX40	86	Q8IX18
KSLEMYGVDLHPVYG	EPB41L4A	201	Q9HCS5
LRHGPFYYMKQPLTT	ZMYND8	61	Q9ULU4
GAYLGSPIYMVKTHL	SLC25A35	116	Q3KQZ1
HYLSPTGVNEYLMAL	CPNE1	306	Q99829
YLDYDLNGPMASGLK	DNAH5	1346	Q8TE73
LTPRSGGHLMNLKYY	MED1	211	Q15648
GGHLMNLKYYVSPSD	MED1	216	Q15648
LLHIGPGNKNYTYMA	NUP210L	1436	Q5VU65
LYPNIMTGHLYAKLV	OR11H1	146	Q8NG94
TLTMPYAHCKGILYG	OSBPL5	531	Q9H0X9
RYSTELGMYQPHCGL	MIOX	171	Q9UGB7
FYGTLCMVYLKPLHT	OR1D2	251	P34982
FYGTLAMVYLQPLHT	OR1D4	251	P47884
FYGTLAMVYLQPLHT	OR1D5	251	P58170
HPLQYRAVMTSGGCY	OR14I1	126	A6ND48
CGSHVGVMALYYLPG	OR52I2	271	Q8NH67
LMRKGSYNPVTHIYT	HEXA	221	P06865
NEKYIPSMHLSSKYG	SPATA17	301	Q96L03
YCMYKTGPVLAISHG	UPP2	101	O95045
YVYDMLAGKLIPVHQ	UTP18	321	Q9Y5J1
PMTRKHYQVTGYGIN	POMT2	431	Q9UKY4
GHYGNKMDLNYKPLV	FER1L5	531	A0AVI2
FSLPHVGYLYMVVKS	HPS3	346	Q969F9
SVYKHHYMDGQTPCL	RHOT2	506	Q8IXI1
YLPYEHGPKGAQMLR	OGA	566	O60502
ALMKHLGYLGYTSGL	SLC38A5	186	Q8WUX1
LGKSHYVLYGLVAAM	PSMD2	811	Q13200
GHMRTNKFCPLYYQT	TAF1	1271	P21675
IDMLYGQPEKNSHRY	PKDREJ	2221	Q9NTG1
DLLMGHTPSCYGQTY	FOXN1	441	O15353
GLAVMYYIAHLLKGA	GPR108	326	Q9NPR9
MRVKITGLDPHQQYY	TBX15	146	Q96SF7
IFIGPTYYQRLKHMV	POLR2B	1041	P30876
LKSPLHYYGNATMSL	ST3GAL6	286	Q9Y274
MGAYHPLLYEKNLVK	ST6GAL1	366	P15907
MTYGGLASPKLDVSY	MYCBP2	2346	O75592
QIPHGATVKRMYIYS	PHAF1	161	Q9BSU1
GHKLRLAYSPTMGLY	NUP160	341	Q12769
YGTLLFMYVQPKSSH	OR8K3	251	Q8NH51
MDLPYYHGRLTKQDC	SH2D1B	1	O14796
IPGYLSYMNGTKALA	ABHD10	81	Q9NUJ1
MRANPLAYGISHKAY	ASCC3	926	Q8N3C0
VAVYPHNGMIDLKYF	ATP1B3	201	P54709
GLGMYIKSTYDGLHV	CNKSR2	226	Q8WXI2
DIFSYLLHIMYTGKG	ZBTB25	71	P24278
AGQHSYYSAMKPIRN	SPATA4	286	Q8NEY3
HFLLYYGRDIPKMQN	SUPT6H	466	Q7KZ85
MIGHYLGEFSITYKP	RPS15	111	P62841
GTNHVEYRYGKAMPL	TPST2	56	O60704
SPGAHYLLTGSYDMK	WDR47	851	O94967
NIHYPSKKMTGSGIY	VNN1	266	O95497
GQRYGSHKDLYILMS	RBP3	831	P10745
GKGPILMELQTYRYH	PDHA1	276	P08559
YTGKPGYKLCMRLHL	TRAF6	381	Q9Y4K3
LDPTKGNCYMHYGQF	TMTC2	706	Q8N394
YYTHPAGCLLNKMLL	SERINC4	246	A6NH21
SGLEPDHKYKMNLYG	TNXB	3116	P22105
QMGSGDAYPHQYSLK	TPP2	866	P29144
KYGLMPQVLRYHVVA	STAB2	1651	Q8WWQ8
KKPLLVHVYGAYGMD	PREPL	471	Q4J6C6
YLYGVTQPKHLSASM	PILRB	31	Q9UKJ0
LYHRSFGPIEYKGPM	TXNDC11	186	Q6PKC3
NYRMIKKSGESYPVH	ZNF644	746	Q9H582
AYKEYRPHLVDQGAM	TGM1	651	P22735
LNYFLQHLVGPKMGA	UBE4A	881	Q14139
HTGVKPCKYMEYGNT	ZNF529	221	Q6P280
ISLLGYMKHYRNIPG	SMARCA5	216	O60264
YPYSILLGHEGKMAV	VWA8	341	A3KMH1
HYTLNSEAPLYVGGM	SLIT1	1276	O75093
MYDPKTRSLNYCGHI	USP7	691	Q93009
HNGKIYPYLVMNDAC	TRRAP	3521	Q9Y4A5
SYYGLMLFGHPLLVS	USP11	606	P51784
SDLMGLIPKYNHLVY	UBR5	1796	O95071
LREGEPYLNTAYGHM	TM6SF1	96	Q9BZW5
GNMLQIGYHLEKYLS	GLYATL2	236	Q8WU03
KLINYIEMHGLYTEG	MYO9A	2081	B2RTY4
ANPGKYIIESRYGMH	MYOM1	321	P52179