Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.49e-0941554GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.49e-0941554GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.49e-0941554GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.74e-0851554GO:0047787
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.18e-0861554GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0771554GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.39e-0781554GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.39e-0781554GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.39e-0781554GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.27e-0791554GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.27e-0791554GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.07e-07101554GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.07e-07101554GO:0032052
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.97e-07241555GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.52e-06261555GO:0004022
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.86e-06271555GO:0008106
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.22e-06301555GO:0018455
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.29e-06141554GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.29e-06141554GO:0001758
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.49e-06321555GO:0004033
GeneOntologyMolecularFunctionactin filament binding

MYH1 MYO1H PSTPIP2 PSTPIP1 NEB MYO5C SPTBN4 XIRP2 MACF1 SCIN

1.15e-0522715510GO:0051015
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-05201554GO:0004303
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

3.46e-05481555GO:0016620
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH1 ANK3 CLIP2 MYO1H NUF2 ADGRV1 PSTPIP2 PSTPIP1 NEB MEFV MYO5C SPTBN4 KIF9 KIF2B KCNC1 XIRP2 SVBP MACF1 SCIN ALDOC MYBPC1 MYBPC2

4.15e-05109915522GO:0008092
GeneOntologyMolecularFunctionNADPH binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.57e-05261554GO:0070402
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C3

7.23e-05111553GO:0030283
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

7.33e-05561555GO:0016903
GeneOntologyMolecularFunctionactin binding

MYH1 MYO1H PSTPIP2 PSTPIP1 NEB MEFV MYO5C SPTBN4 XIRP2 MACF1 SCIN MYBPC1 MYBPC2

9.59e-0547915513GO:0003779
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C4 AKR1C1 AKR1C2 NDUFS1 AKR1C3

1.02e-04601555GO:0016655
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-04331554GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.35e-04341554GO:0016628
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.32e-04391554GO:0016229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.57e-04401554GO:0016709
GeneOntologyMolecularFunctionbeta-catenin binding

CDHR5 TBL1XR1 MED12L CDH4 CDH6 CDH9

3.50e-041201556GO:0008013
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

3.56e-0441552GO:0047718
GeneOntologyMolecularFunctionenzyme regulator activity

STARD13 PPP4R1 DOCK8 FRS2 ADGRV1 SERPINA2 WNK1 ZEB2 RBCK1 ITIH5 PPP1R10 GPC3 SVBP RASGEF1B SH3BP5L HERC1 TEN1 ACAP2 PREX1 EVI5L ARAP2 SOS1 WDR48

6.05e-04141815523GO:0030234
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

SUPT20H ANK3 KAT6A NIPSNAP1 ZMYND8 FRS2 KMT2E WNK1 TBL1XR1 RBCK1 SPTBN4 KMT2D AP2A2 AP2B1 TRIM62 EPC1 MED12L SMARCD1 CAMTA1 SOS1

6.69e-04116015520GO:0030674
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

AKR1C4 AKR1C1 AKR1C2 NDUFS1 AKR1C3

8.73e-04951555GO:0016651
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 ERCC6L TCP1 MYO1H RNF213 CHD2 FANCM ATP10D MYO5C KIF9 KIF2B SHPRH MACF1

1.02e-0361415513GO:0140657
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.37e-03621554GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.37e-03621554GO:0050661
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.49e-031071555GO:0033293
GeneOntologyMolecularFunctionlipid binding

STARD13 AMPH CYP27C1 PCLO PHB2 AKR1C4 AKR1C1 AKR1C2 PITPNM1 SPTBN4 AP2A2 AKR1C3 SCIN ACAP2 PREX1 VPS13B ARAP2

1.76e-0398815517GO:0008289
GeneOntologyMolecularFunctionmonooxygenase activity

CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.04e-031151555GO:0004497
GeneOntologyMolecularFunctiontestosterone dehydrogenase (NAD+) activity

AKR1C4 AKR1C3

2.08e-0391552GO:0047035
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYO1H MYO5C KIF9 KIF2B

2.29e-031181555GO:0003774
GeneOntologyMolecularFunctionribosome binding

SRP19 NCLN NOMO1 NOMO2 NOMO3

2.46e-031201555GO:0043022
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

ERCC6L CHD2 SHPRH

2.94e-03371553GO:0140658
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.14e-031271555GO:0016616
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

MTMR4 SYNJ1

3.14e-03111552GO:0052629
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYO1H MYO5C

3.17e-03381553GO:0000146
GeneOntologyMolecularFunctionmolecular adaptor activity

SUPT20H ANK3 KAT6A NIPSNAP1 ZMYND8 FRS2 KMT2E WNK1 TBL1XR1 RBCK1 SPTBN4 KMT2D AP2A2 AP2B1 TRIM62 EPC1 MED12L SMARCD1 CAMTA1 SOS1

4.21e-03135615520GO:0060090
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.48e-031381555GO:0016614
GeneOntologyMolecularFunctiontranscription coregulator activity

SUPT20H KAT6A ZMYND8 KMT2E TBL1XR1 RBCK1 KMT2D TRIM62 MED12L SMARCD1 CAMTA1

4.50e-0356215511GO:0003712
GeneOntologyMolecularFunctionstructural constituent of muscle

NEB MYBPC1 MYBPC2

4.51e-03431553GO:0008307
GeneOntologyMolecularFunctionphosphatase binding

AMPH PSTPIP1 WNK1 SPTBN4 PPP1R10 MTMR4 ANAPC5

4.62e-032641557GO:0019902
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

MTMR4 SYNJ1

5.12e-03141552GO:0004438
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

MTMR4 SYNJ1

5.88e-03151552GO:0052744
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NADP+) activity

DHRS3 AKR1C3

5.88e-03151552GO:0052650
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.91e-0941534GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.91e-0941534GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.91e-0941534GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.91e-0941534GO:0008208
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-0851534GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.32e-0861534GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.32e-0861534GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.00e-0771534GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.00e-0771534GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.00e-0771534GO:1900052
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.56e-0791534GO:0044597
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NCLN NOMO1 NOMO2 NOMO3

3.56e-0791534GO:0160063
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.89e-07211535GO:0048385
GeneOntologyBiologicalProcessretinal metabolic process

CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.89e-07211535GO:0042574
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.90e-07101534GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.90e-07101534GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.90e-07101534GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.90e-07101534GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.90e-07101534GO:0030647
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

6.35e-07231535GO:0034310
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.23e-07111534GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.23e-07111534GO:0016115
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.75e-06141534GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.75e-06141534GO:0008300
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NCLN WNK1 NOMO1 NOMO2 NOMO3

3.06e-06311535GO:0045048
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 COL18A1 AKR1C3

3.60e-06321535GO:2000353
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.73e-06151534GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.94e-06161534GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.94e-06161534GO:0032351
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.21e-06181534GO:0030656
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.67e-06381535GO:0048384
GeneOntologyBiologicalProcessretinoic acid metabolic process

CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.12e-05401535GO:0042573
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NCLN NOMO1 NOMO3

1.37e-0571533GO:1900108
GeneOntologyBiologicalProcessprimary alcohol metabolic process

DHRS3 CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

1.42e-051061537GO:0034308
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3 SMARCD1

1.43e-05421535GO:0071398
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.58e-05211534GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.58e-05211534GO:0016114
GeneOntologyBiologicalProcessketone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.58e-05211534GO:0042182
GeneOntologyBiologicalProcessparturition

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-05221534GO:0007567
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-05221534GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-05221534GO:0042448
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-05221534GO:1902644
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-05231534GO:0071379
GeneOntologyBiologicalProcessalcohol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

2.51e-05471535GO:0046164
GeneOntologyBiologicalProcessregulation of chromosome organization

KNTC1 TCP1 NUF2 TTK PPP1R10 XRN1 SMARCD1 PARN TEN1 ANAPC5

3.06e-0526615310GO:0033044
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

NCLN NOMO1 NOMO3

3.25e-0591533GO:1900107
GeneOntologyBiologicalProcessprotein insertion into membrane

NCLN WNK1 NOMO1 NOMO2 NOMO3

3.40e-05501535GO:0051205
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.83e-05261534GO:0010566
GeneOntologyBiologicalProcessdetermination of left/right asymmetry in lateral mesoderm

NCLN NOMO1 NOMO3

4.62e-05101533GO:0003140
GeneOntologyBiologicalProcesscellular response to calcium ion

AKR1C4 ADGRV1 WNK1 AKR1C1 AKR1C2 AKR1C3

4.96e-05881536GO:0071277
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.19e-05281534GO:0048025
GeneOntologyBiologicalProcessretinoid metabolic process

DHRS3 CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.28e-05891536GO:0001523
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.98e-05291534GO:0016093
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.98e-05291534GO:0050686
GeneOntologyBiologicalProcessditerpenoid metabolic process

DHRS3 CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.18e-05941536GO:0016101
GeneOntologyBiologicalProcesspositive regulation of epithelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 COL18A1 AKR1C3

8.27e-05601535GO:1904037
GeneOntologyBiologicalProcesslocalization within membrane

FLOT2 ANK3 ZMYND8 SRP19 NCLN WNK1 NOMO1 SPTBN4 GPC3 AP2B1 NOMO2 VPS35 PEX16 MACF1 ACAP2 VPS13B NOMO3

9.25e-0579815317GO:0051668
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.01e-04331534GO:0033119
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.14e-04341534GO:0006706
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.27e-04351534GO:0120255
GeneOntologyBiologicalProcessterpenoid metabolic process

DHRS3 CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.33e-041051536GO:0006721
GeneOntologyBiologicalProcessestablishment of protein localization to membrane

ANK3 SRP19 NCLN WNK1 NOMO1 NOMO2 VPS35 PEX16 MACF1 NOMO3

1.39e-0431915310GO:0090150
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C4 AKR1C1 AKR1C2 ZEB2 AKR1C3

1.40e-04671535GO:0019748
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.43e-04361534GO:0034694
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.43e-04361534GO:0008299
GeneOntologyBiologicalProcessendoplasmic reticulum organization

NCLN MYZAP WNK1 NOMO1 NOMO2 NOMO3

1.47e-041071536GO:0007029
GeneOntologyBiologicalProcessresponse to fatty acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3 SMARCD1

1.61e-04691535GO:0070542
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDH1B1

2.11e-04731535GO:1901616
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 COL18A1 AKR1C3

2.24e-04741535GO:2000351
GeneOntologyBiologicalProcessprotein localization to membrane

FLOT2 ANK3 ZMYND8 SRP19 NCLN WNK1 NOMO1 SPTBN4 GPC3 AP2B1 NOMO2 VPS35 PEX16 MACF1 NOMO3

2.47e-0470515315GO:0072657
GeneOntologyBiologicalProcessendothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 COL18A1 AKR1C3

3.05e-04791535GO:0072577
GeneOntologyBiologicalProcessaxon development

SEMA4D ANK3 B4GAT1 ENPP1 WNT7B LAMC3 ZEB2 B4GALT5 SPTBN4 SLITRK2 SVBP MACF1 CDH4 SOS1

3.12e-0464215314GO:0061564
GeneOntologyBiologicalProcesspositive regulation of establishment of T cell polarity

FLOT2 DOCK8

3.25e-0441532GO:1903905
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.42e-04451534GO:0008207
GeneOntologyBiologicalProcessregulation of cellular component size

SEMA4D WNT7B PCLO CDHR5 NEB WNK1 SPTBN4 MACF1 SCIN CDH4 PREX1

3.47e-0442615311GO:0032535
GeneOntologyBiologicalProcesslateral mesoderm development

NCLN NOMO1 NOMO3

4.16e-04201533GO:0048368
GeneOntologyBiologicalProcessvitamin metabolic process

ENPP1 FPGS AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.77e-041331536GO:0006766
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

NCLN NOMO1 NOMO3

4.83e-04211533GO:0032926
GeneOntologyBiologicalProcessregulation of chromosome segregation

KNTC1 NUF2 TTK KIF2B SMARCD1 ANAPC5

6.03e-041391536GO:0051983
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

KNTC1 NUF2 TTK SMARCD1 ANAPC5

7.13e-04951535GO:0030071
GeneOntologyBiologicalProcessaldehyde metabolic process

CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.13e-04951535GO:0006081
GeneOntologyBiologicalProcessisoprenoid metabolic process

DHRS3 CYP27C1 AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.26e-041441536GO:0006720
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

DHRS3 PHB2 AKR1C4 AKR1C1 AKR1C2 KMT2D AKR1C3

7.91e-042021537GO:0141193
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.92e-04561534GO:0006693
GeneOntologyBiologicalProcessregulation of protein monoubiquitination

FANCM WDR48

8.04e-0461532GO:1902525
GeneOntologyBiologicalProcessregulation of establishment of T cell polarity

FLOT2 DOCK8

8.04e-0461532GO:1903903
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

KNTC1 NUF2 TTK SMARCD1 ANAPC5

8.21e-04981535GO:1902099
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.47e-04571534GO:0006692
GeneOntologyBiologicalProcessketone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.47e-04571534GO:0042181
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

KNTC1 NUF2 TTK SMARCD1 ANAPC5

8.99e-041001535GO:0007091
GeneOntologyBiologicalProcessregulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.05e-04581534GO:0032350
GeneOntologyBiologicalProcessnodal signaling pathway

NCLN NOMO1 NOMO3

9.18e-04261533GO:0038092
GeneOntologyBiologicalProcessregulation of organelle organization

KNTC1 TCP1 ZMYND8 NUF2 NEB TTK ZEB2 SPTBN4 PPP1R10 KIF9 SYNJ1 XIRP2 VPS35 XRN1 SMARCD1 PARN TEN1 SCIN ANAPC5 PREX1 EVI5L

9.40e-04134215321GO:0033043
GeneOntologyBiologicalProcessactin cytoskeleton organization

STARD13 MYO1H PCLO PSTPIP2 THSD7B PSTPIP1 NEB ZEB2 MYO5C SPTBN4 XIRP2 SCIN PREX1 MYBPC1 MYBPC2

9.51e-0480315315GO:0030036
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

DHRS3 ENPP1 CYP27C1 AKR1C4 AKR1C1 AKR1C2 ZEB2 NUDT11 SYNJ1 CPQ VPS35 AKR1C3 ALDH1B1

1.00e-0364115313GO:1901615
GeneOntologyCellularComponentmulti-pass translocon complex

NCLN NOMO1 NOMO2 NOMO3

3.56e-0791554GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NCLN NOMO1 NOMO2 NOMO3

2.75e-06141554GO:0072379
GeneOntologyCellularComponentactin cytoskeleton

KNTC1 MYH1 FLOT2 AMPH MYO1H PSTPIP2 PSTPIP1 MYZAP NEB MYO5C SPTBN4 KIF9 XIRP2 MACF1 SCIN

2.61e-0557615515GO:0015629
MousePhenoparturition failure

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.10e-07101164MP:0012010
MousePhenohypermyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.42e-06111164MP:0010050
MousePhenoincreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.04e-06131164MP:0010160
MousePhenoincreased circulating progesterone level

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.73e-06151164MP:0005186
MousePhenolong stride length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.73e-06151164MP:0010540
MousePhenolong gestation period

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.73e-06151164MP:0002293
MousePhenoabnormal gestational length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.26e-05181164MP:0002292
MousePhenoabnormal ear physiology

MYH1 ENPP1 FRS2 AKR1C4 CACHD1 ADGRV1 PSTPIP2 TBL1XR1 AKR1C1 AKR1C2 PITPNM1 SPTBN4 SLITRK2 ACAN AKR1C3 BZW1 HERC1 ALDOC

1.29e-0568411618MP:0003878
MousePhenoenhanced coordination

AKR1C4 AKR1C1 AKR1C2 SLITRK2 AKR1C3

1.46e-05381165MP:0003858
MousePhenodysmyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.97e-05201164MP:0013438
MousePhenoabnormal auditory brainstem response

MYH1 ENPP1 FRS2 AKR1C4 CACHD1 ADGRV1 TBL1XR1 AKR1C1 AKR1C2 PITPNM1 SPTBN4 ACAN AKR1C3 BZW1 HERC1 ALDOC

2.13e-0557611616MP:0004738
MousePhenoabnormal hearing electrophysiology

MYH1 ENPP1 FRS2 AKR1C4 CACHD1 ADGRV1 TBL1XR1 AKR1C1 AKR1C2 PITPNM1 SPTBN4 ACAN AKR1C3 BZW1 HERC1 ALDOC

3.10e-0559411616MP:0006335
MousePhenodecreased vocalization

AKR1C4 AKR1C1 AKR1C2 AKR1C3 PREX1

3.77e-05461165MP:0020351
MousePhenodecreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.98e-05251164MP:0009808
MousePhenoabnormal hearing physiology

MYH1 ENPP1 FRS2 AKR1C4 CACHD1 ADGRV1 TBL1XR1 AKR1C1 AKR1C2 PITPNM1 SPTBN4 ACAN AKR1C3 BZW1 HERC1 ALDOC

7.96e-0564311616MP:0001963
MousePhenoabnormal locomotor coordination

ANK3 ENPP1 FAM91A1 AKR1C4 CACHD1 NEB AKR1C1 AKR1C2 SPTBN4 ZNF106 KMT2D SYNJ1 ACAN VPS35 AKR1C3 HERC1 CAMTA1

9.86e-0572611617MP:0003312
MousePhenoabnormal gait

ANK3 ENPP1 FAM91A1 AKR1C4 NEB AKR1C1 AKR1C2 SPTBN4 ZNF106 KMT2D ACAN VPS35 AKR1C3 HERC1

1.01e-0452011614MP:0001406
MousePhenoprolonged diestrus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.04e-04301164MP:0009011
MousePhenoabnormal parturition

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.53e-04331164MP:0002907
MousePhenohearing/vestibular/ear phenotype

MYH1 ENPP1 FRS2 AKR1C4 CACHD1 ADGRV1 PSTPIP2 TBL1XR1 AKR1C1 AKR1C2 PITPNM1 SPTBN4 KMT2D SLITRK2 ACAN AKR1C3 BZW1 HERC1 ALDOC

1.56e-0490511619MP:0005377
MousePhenoabnormal diestrus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.93e-04351164MP:0009010
MousePhenoprolonged estrous cycle

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.96e-04391164MP:0009006
MousePhenoabnormal motor coordination/balance

ANK3 CLIP2 MYO1H AKR1C4 CACHD1 AKR1C1 AKR1C2 SPTBN4 ZNF106 KMT2D SLITRK2 SYNJ1 VPS35 AKR1C3 HERC1 CAMTA1 CDH4 VPS13B

2.96e-0487311618MP:0001516
MousePhenoabnormal spine curvature

MYH1 ENPP1 PABPC4 CHD2 PSTPIP1 NEB ATXN1L ZNF106 ACAN MYBPC1

3.12e-0431811610MP:0004174
DomainALDOKETO_REDUCTASE_1

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.66e-07101484PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.66e-07101484PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.66e-07101484PS00063
DomainAldo/ket_reductase_CS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.66e-07101484IPR018170
DomainAldo/keto_reductase

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.66e-07101484IPR020471
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.94e-0641483PF09430
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.94e-0641483IPR019008
Domain-

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.40e-061614843.20.20.100
DomainNADP_OxRdtase_dom

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.32e-06171484IPR023210
DomainAldo_ket_red

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.32e-06171484PF00248
DomainAldo/ket_red/Kv-b

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.32e-06171484IPR001395
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

2.65e-0581483IPR013784
DomainRibosomal_L26

RPL26 RPL26L1

6.24e-0521482PF16906
DomainRibosomal_L26/L24P_euk/arc

RPL26 RPL26L1

6.24e-0521482IPR005756
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

1.32e-04131483IPR014766
Domain-

NOMO1 NOMO2 NOMO3

1.32e-041314832.60.40.1120
DomainZnf_FYVE_PHD

PCLO KAT6A ZMYND8 KMT2E KMT2D MTMR4 SHPRH

1.72e-041471487IPR011011
DomainRibosomal_L24/26_CS

RPL26 RPL26L1

1.86e-0431482IPR005825
DomainRIBOSOMAL_L24

RPL26 RPL26L1

1.86e-0431482PS01108
Domain-

PCLO KAT6A MARCHF6 ZMYND8 RNF213 KMT2E RBCK1 KMT2D MTMR4 TRIM62 SHPRH PDZRN4

2.46e-04449148123.30.40.10
DomainZnf_RING/FYVE/PHD

PCLO KAT6A MARCHF6 ZMYND8 RNF213 KMT2E RBCK1 KMT2D MTMR4 TRIM62 SHPRH PDZRN4

3.00e-0445914812IPR013083
DomainCarboxyPept-like_regulatory

NOMO1 NOMO2 NOMO3

3.06e-04171483IPR008969
DomainPRY

BTN3A1 MEFV BTN3A3 TRIM62

3.35e-04421484PF13765
DomainPRY

BTN3A1 MEFV BTN3A3 TRIM62

5.62e-04481484SM00589
DomainPRY

BTN3A1 MEFV BTN3A3 TRIM62

5.62e-04481484IPR006574
DomainPolyA

PABPC4 PABPC1L

6.14e-0451482SM00517
Domain-

PABPC4 PABPC1L

6.14e-04514821.10.1900.10
DomainPABP

PABPC4 PABPC1L

6.14e-0451482PF00658
DomainPABP_1234

PABPC4 PABPC1L

6.14e-0451482IPR006515
DomainPABC

PABPC4 PABPC1L

6.14e-0451482PS51309
DomainPABP_HYD

PABPC4 PABPC1L

6.14e-0451482IPR002004
DomainSPRY

BTN3A1 MEFV BTN3A3 TRIM62 HERC1

6.40e-04871485SM00449
DomainPHD

KAT6A ZMYND8 KMT2E KMT2D SHPRH

7.10e-04891485SM00249
DomainZnf_PHD

KAT6A ZMYND8 KMT2E KMT2D SHPRH

7.86e-04911485IPR001965
DomainSPRY

BTN3A1 MEFV BTN3A3 TRIM62 HERC1

9.10e-04941485PF00622
DomainSPRY_dom

BTN3A1 MEFV BTN3A3 TRIM62 HERC1

9.10e-04941485IPR003877
DomainB30.2/SPRY

BTN3A1 MEFV BTN3A3 TRIM62 HERC1

9.54e-04951485IPR001870
DomainB302_SPRY

BTN3A1 MEFV BTN3A3 TRIM62 HERC1

9.54e-04951485PS50188
DomainZF_PHD_2

KAT6A ZMYND8 KMT2E KMT2D SHPRH

9.54e-04951485PS50016
DomainCadherin_C

CDH4 CDH6 CDH9

9.87e-04251483PF01049
DomainCadherin_cytoplasmic-dom

CDH4 CDH6 CDH9

9.87e-04251483IPR000233
DomainZF_PHD_1

KAT6A ZMYND8 KMT2E KMT2D SHPRH

1.00e-03961485PS01359
DomainKOW

RPL26 RPL26L1

1.28e-0371482SM00739
DomainCatenin_binding_dom

CDH4 CDH6 CDH9

1.53e-03291483IPR027397
Domain-

CDH4 CDH6 CDH9

1.53e-032914834.10.900.10
DomainARM-type_fold

PPP4R1 DOCK8 AP2A2 AP2B1 VPS35 BZW1 HEATR5B TARBP1 KPNA3

1.55e-033391489IPR016024
DomainAH/BAR-dom

AMPH CIBAR2 ACAP2

1.69e-03301483IPR027267
Domain-

AMPH CIBAR2 ACAP2

1.69e-033014831.20.1270.60
DomainCoatomer/calthrin_app_sub_C

AP2A2 AP2B1

1.69e-0381482IPR009028
DomainConA-like_dom

ADGRV1 BTN3A1 MEFV COL18A1 BTN3A3 TRIM62 HERC1

1.83e-032191487IPR013320
DomainSNF2_N

ERCC6L CHD2 SHPRH

2.04e-03321483IPR000330
DomainSNF2_N

ERCC6L CHD2 SHPRH

2.04e-03321483PF00176
DomainAlpha_adaptinC2

AP2A2 AP2B1

2.16e-0391482PF02883
DomainClathrin_a/b/g-adaptin_app_Ig

AP2A2 AP2B1

2.16e-0391482IPR008152
DomainAlpha_adaptinC2

AP2A2 AP2B1

2.16e-0391482SM00809
DomainButyrophylin

BTN3A1 MEFV BTN3A3 TRIM62

2.31e-03701484IPR003879
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.89e-0791194M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.89e-0791194M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.52e-06111194M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.25e-06131194M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.25e-06131194MM14747
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.31e-06281195MM15188
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.53e-06141194M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.53e-06141194M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.53e-06141194M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.53e-06141194MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.13e-06151194MM14870
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C4 AKR1C1 AKR1C2 GPC3 AKR1C3

3.67e-05451195MM15344
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.78e-05231194M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.78e-05231194MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.78e-05231194MM14741
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

DHRS3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.58e-05491195MM15186
PathwayREACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS

BTN3A2 BTN3A1 BTN3A3

1.22e-04121193M27738
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

DHRS3 AKR1C4 AKR1C1 AKR1C2 GPC3 AKR1C3

1.26e-04921196MM14881
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.63e-04331194M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.63e-04331194MM14737
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

ZEB2 CDH4 CDH6 CDH9

3.49e-04401194MM15060
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.05e-04441194M499
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.51e-04451194MM14751
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

ZEB2 CDH4 CDH6 CDH9

7.05e-04481194MM15069
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C4 AKR1C1 GPC3 AKR1C3

7.05e-04481194M27642
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157420124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157410500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157416508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157419487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157414967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157410393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157415193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157431479646
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157415222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157416191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157415577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157410702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157417034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157417629694
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157429764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157410526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157417888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157417442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157428329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157416018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157417272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157419237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157418667791
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157428259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157421521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-10415748274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157416511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157410803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-104157434590152
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.00e-10415747789999
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PPP4R1 SEMA4D SUPT20H ANK3 B4GAT1 CLIP2 PEG3 ZMYND8 CACHD1 HUNK WDR26 ZEB2 RBCK1 SPTBN4 THOP1 TMEM168 AP2B1 SYNJ1 NOMO2 AKR1C3 MACF1 PREX1 TARBP1 SOS1 KPNA3

7.79e-1012851572535914814
Pubmed

Functional proteomics mapping of a human signaling pathway.

STARD13 ANK3 DOCK8 PABPC4 ZMYND8 ZEB2 NOMO1 PPP1R10 ZNF106 KMT2D MTMR4 AP2A2 TRIM62 VPS35 MACF1 HERC1 NOMO3

1.78e-095911571715231748
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-09515747737980
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157421851338
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157417872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157417064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157410672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157438788959
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157416984997
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-095157418003893
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLOT2 VRK2 TCP1 ENPP1 PABPC4 NIPSNAP1 LAMC3 NCLN WNK1 TTK NDUFS1 COL18A1 ZNF106 MTMR4 THOP1 AP2B1 NOMO2 RPL26L1 GOLIM4 MACF1 PARN BZW1 SRRM2 KPNA3

4.69e-0912971572433545068
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157429107092
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157419273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157415860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157415471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157426748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157417122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.95e-096157417255200
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157426160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157434843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157422529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157433127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157412562828
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-087157416337335
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NCLN NOMO1 NOMO2 NOMO3

2.76e-088157415257293
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.76e-088157433584538
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.76e-088157420837989
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.76e-08815749224647
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL26 FLOT2 AMPH ANK3 CLIP2 TCP1 DOCK8 PCLO PABPC4 NIPSNAP1 PHB2 FAM98A NDUFS1 PITPNM1 SPTBN4 AP2A2 AP2B1 SYNJ1 VPS35 XRN1 MACF1 ALDH1B1 ALDOC KPNA3

3.05e-0814311572437142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

STARD13 KNTC1 RPL26 MYH1 PCLO PABPC4 PHB2 CHD2 FAM98A NEB ZEB2 NDUFS1 SPTBN4 AP2A2 AP2B1 RPL26L1 VPS35 XRN1 MACF1 PABPC1L ALDH1B1 PREX1 MYBPC1 MYBPC2

3.52e-0814421572435575683
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

FLOT2 TCP1 PHB2 RNF213 FAM98A AKR1C2 MYO5C AP2A2 AP2B1 AKR1C3 SRRM2

4.30e-082681571133024031
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NCLN NOMO1 NOMO2 NOMO3

4.95e-089157436261522
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.95e-089157433348080
Pubmed

A protein interaction framework for human mRNA degradation.

PABPC4 PHB2 WNK1 NOMO1 COL18A1 THOP1 NOMO2 XRN1 PARN ALDH1B1 SRRM2 NOMO3

6.72e-083471571215231747
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.22e-0810157436313771
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

9.02e-083157319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

9.02e-083157331780644
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C4 AKR1C1 AKR1C3

9.02e-08315737626489
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

9.02e-083157321232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

9.02e-083157313678667
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

9.02e-083157336011023
Pubmed

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.

BTN3A2 BTN3A1 BTN3A3

9.02e-083157322767497
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

9.02e-083157325576386
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HK3 ANK3 PEG3 FAM91A1 CHD2 AKR1C4 ITGA9 WNK1 ATXN1L AKR1C1 AKR1C2 COL18A1 THOP1 SYNJ1 AKR1C3 MACF1 HERC1 CAMTA1 VPS13B KPNA3

1.07e-0710841572011544199
Pubmed

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

AKR1C4 NEB AKR1C1 AKR1C2 AKR1C3

1.07e-0726157523892084
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NCLN NOMO1 NOMO2 NOMO3

1.29e-0711157432820719
Pubmed

Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.

AKR1C4 AKR1C1 AKR1C2 ACAN AKR1C3

1.59e-0728157521820362
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-0712157421256921
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-0712157428893949
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-0712157425774556
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.77e-0713157411682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.77e-0713157417062636
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.77e-0713157415117747
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.77e-0713157424580729
Pubmed

Defining the membrane proteome of NK cells.

RPL26 FLOT2 ERCC6L DOCK8 MARCHF6 RNF213 NUF2 PSTPIP1 NCLN TTK BTN3A2 NOMO1 BTN3A3 AP2B1 XRN1 PEX16 GOLIM4 BZW1 HEATR5B ACAP2

3.49e-0711681572019946888
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

3.60e-074157331833031
Pubmed

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.

BTN3A2 BTN3A1 BTN3A3

3.60e-074157339142074
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

3.60e-07415739267806
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.86e-0714157419955443
Pubmed

Placental endocrine function shapes cerebellar development and social behavior.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.86e-0714157434400844
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

PEG3 CHD2 NEB KMT2E WNK1 AKR1C2 NDUFS1 GPC3 XIRP2 MED12L MACF1 MYBPC1 MYBPC2

4.65e-074971571323414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

SUPT20H ANK3 ZMYND8 CHD2 NCLN NEB PPP1R10 ZNF106 KIF2B XIRP2 VPS35 SHPRH HERC1

4.65e-074971571336774506
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

TCP1 NOMO1 AP2A2 AP2B1 NOMO2 SMARCD1 ACAP2 NOMO3

5.94e-07156157830409884
Pubmed

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

BTN3A2 BTN3A1 BTN3A3

8.97e-075157329339503
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C1 AKR1C2 AKR1C3

8.97e-075157315212687
Pubmed

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.09e-0717157432243503
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CLIP2 ADGRV1 WNK1 AP2A2 SYNJ1 MACF1 CAMTA1 PREX1 WDR48

9.34e-07225157912168954
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

VRK2 SUPT20H PABPC4 ZMYND8 PUSL1 SRP19 FAM91A1 CHD2 FAM98A TBL1XR1 NDUFS1 NOMO1 PPP1R10 COL18A1 XRN1 GOLIM4 MACF1 PARN HEATR5B ANAPC5 PREX1 KPNA3

1.13e-0614971572231527615
Pubmed

A protein interaction landscape of breast cancer.

FLOT2 ANK3 PABPC4 SRP19 TBL1XR1 PPP1R10 ZNF106 AP2A2 AP2B1 GOLIM4 SMARCD1 MACF1 WDR48 KPNA3

1.24e-066341571434591612
Pubmed

Functional dynamics of H3K9 methylation during meiotic prophase progression.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.47e-0619157417599069
InteractionAKR1C4 interactions

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.13e-0781524int:AKR1C4
InteractionAKR1C3 interactions

AKR1C4 HUNK AKR1C1 AKR1C2 AKR1C3

8.20e-06371525int:AKR1C3
InteractionKIF20A interactions

RPL26 FLOT2 PCLO PABPC4 PHB2 CHD2 FAM98A ZEB2 SPTBN4 ZNF106 AP2A2 AP2B1 RPL26L1 XRN1 MACF1 PABPC1L SH3BP5L ALDH1B1 HERC1 SRRM2 SCIN CDH9

1.36e-05105215222int:KIF20A
InteractionAKR1C1 interactions

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.37e-05201524int:AKR1C1
InteractionXIRP2 interactions

MYH1 PABPC4 NEB TTK XIRP2

3.01e-05481525int:XIRP2
InteractionCIT interactions

RPL26 FLOT2 VRK2 TCP1 MYO1H PCLO PABPC4 NIPSNAP1 ZMYND8 PHB2 RNF213 CHD2 FAM98A NUF2 ADGRV1 SPTBN4 MTMR4 AP2A2 AP2B1 RPL26L1 MACF1 PABPC1L HERC1 SRRM2 TARBP1 KPNA3

3.07e-05145015226int:CIT
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

7.64e-076156310p15-p14
CytobandEnsembl 112 genes in cytogenetic band chr10p15

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.61e-04901564chr10p15
GeneFamilyAldo-keto reductases

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.19e-06151014399
GeneFamilyButyrophilins|V-set domain containing|C2-set domain containing

BTN3A2 BTN3A1 BTN3A3

7.33e-05151013458
GeneFamilyPHD finger proteins

KAT6A ZMYND8 KMT2E KMT2D SHPRH

1.49e-0490101588
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC1 MYBPC2

8.46e-0481012658
GeneFamilyCD molecules|Type II classical cadherins

CDH6 CDH9

2.32e-031310121186
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RPL26 SEMA4D FLOT2 TCP1 DOCK8 GIMAP2 KAT6A MARCHF6 RNF213 CHD2 PSTPIP1 KMT2E WNK1 TBL1XR1 WDR26 BTN3A2 BTN3A1 ZEB2 KMT2D EPC1 XRN1 OXNAD1 MACF1 BZW1 HERC1 ACAP2 PREX1 VPS13B ARAP2 SOS1

3.24e-09149215530M40023
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

KNTC1 DOCK8 WNK1 PPP1R10 ZNF106 MED12L SMARCD1 MACF1 HERC1 ARAP2 SOS1

1.08e-0818015511M8239
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C4 AKR1C1 AKR1C2 AKR1C3 SCIN

3.96e-08171555MM826
CoexpressionDELYS_THYROID_CANCER_DN

STARD13 ENPP1 PCLO NEB AKR1C1 ITIH5 MTMR4 GPC3 CPQ ALDH1B1

1.35e-0623315510M13273
CoexpressionGSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_UP

STARD13 PCLO PEG3 CTRC TBL1XR1 SPTBN4 AKR1C3 CDH6 MYBPC2

2.78e-061971559M4985
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN

MYH1 TCP1 TBL1XR1 PITPNM1 PPP1R10 MACF1 HERC1 TARBP1 KPNA3

2.90e-061981559M4981
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

AKR1C4 AKR1C1 AKR1C2 ITIH5 GPC3 AKR1C3

7.56e-06791556MM535
CoexpressionBUSSLINGER_DUODENAL_IMMUNE_CELLS

RPL26 SEMA4D FLOT2 DOCK8 GIMAP2 KAT6A CHD2 PSTPIP1 KMT2E WNK1 WDR26 BTN3A1 OXNAD1 MACF1 BZW1 HERC1 PREX1 ARAP2

7.90e-0691115518M40038
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.14e-05241554MM766
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.35e-05251554MM480
CoexpressionMARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP

PEG3 ITGA9 NOMO1 GPC3 NOMO2 SRRM2 NOMO3 ARAP2

1.50e-051851558MM1115
CoexpressionRICKMAN_HEAD_AND_NECK_CANCER_F

MYH1 NEB XIRP2 MYBPC1 MYBPC2

1.86e-05551555M2043
CoexpressionGSE11924_TH1_VS_TH17_CD4_TCELL_DN

FAM91A1 CHD2 PSTPIP2 ATP10D PITPNM1 AKR1C3 SH3BP5L REV1

2.54e-051991558M3163
CoexpressionGSE27786_LIN_NEG_VS_MONO_MAC_DN

SEMA4D MYO1H WNT7B ATXN1L WDR26 KMT2D AP2A2 VPS13B

2.64e-052001558M4798
CoexpressionGSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP

KAT6A BTN3A1 NDUFS1 PITPNM1 PPP1R10 THOP1 AP2B1 ALDH1B1

2.64e-052001558M5165
CoexpressionDARWICHE_PAPILLOMA_RISK_HIGH_DN

TCP1 PABPC4 AKR1C4 NUF2 AKR1C1 AKR1C2 PEX16 AKR1C3

2.73e-052011558MM500
CoexpressionMARSON_FOXP3_TARGETS_DN

AKR1C4 AKR1C1 AKR1C2 AKR1C3 BZW1

2.85e-05601555MM847
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.86e-05301554MM853
CoexpressionLI_CISPLATIN_RESISTANCE_DN

AKR1C1 GPC3 XIRP2 AKR1C3

4.21e-05331554M10150
CoexpressionGOLDRATH_IMMUNE_MEMORY

AKR1C4 AKR1C1 AKR1C2 AKR1C3 GOLIM4

5.62e-05691555MM621
CoexpressionDESCARTES_ORGANOGENESIS_INTERMEDIATE_MESODERM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.98e-05361554MM3660
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM

DOCK8 PCLO AKR1C4 AKR1C1 AKR1C2 MYO5C COL18A1 AKR1C3

6.66e-052281558MM1014
CoexpressionWANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.67e-05371554MM630
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

AMPH DHRS3 MARCHF6 SRP19 AKR1C4 NUF2 ITGA9 TTK WDR26 AKR1C1 BTN3A2 AKR1C2 BTN3A1 ATP10D BTN3A3 AP2A2 AKR1C3 HERC1 ANAPC5 KPNA3

6.79e-05127715520MM1032
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP

TBL1XR1 ZEB2 PITPNM1 XRN1 MED12L PREX1 ARAP2

8.51e-051751557M6690
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

SUPT20H DHRS3 RNF213 CHD2 CACHD1 TBL1XR1 AKR1C1 ZEB2 KIF9 CPQ PDGFD HERC1 SRRM2 ANAPC5 REV1

9.32e-0580715515M16651
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

STARD13 PEG3 CHD2 NUF2 HUNK WNK1 TBL1XR1 TTK ZEB2 NDUFS1 COL18A1 GPC3 XRN1 PARN CDH4 PREX1 VPS13B

1.04e-04100915517M157
CoexpressionHOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

VRK2 GIMAP2 RNF213 PSTPIP2 ATP10D RBCK1 BTN3A3 XRN1 MED12L TARBP1

1.25e-0439415510M40996
CoexpressionMARTINEZ_RB1_TARGETS_UP

MYH1 ANK3 PEG3 PHB2 AKR1C4 ITGA9 AKR1C1 AKR1C2 ITIH5 ZNF106 UCP3 AKR1C3 BZW1 WDR48

1.36e-0474115514MM1037
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

AMPH ZEB2 ACAP2 VPS13B ARAP2

1.44e-04841555M13008
CoexpressionVARELA_ZMPSTE24_TARGETS_DN

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.45e-04451554MM1173
CoexpressionDARWICHE_PAPILLOMA_RISK_LOW_UP

TCP1 AKR1C4 AKR1C1 AKR1C2 ACAN AKR1C3 BZW1

1.51e-041921557MM497
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS

ANK3 PCLO MTMR4 NUDT11 AP2B1 EVI5L

1.62e-041361556MM407
CoexpressionGSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP

FLOT2 SUPT20H HK3 CDHR5 NEB ATP10D AKR1C3

1.67e-041951557M3184
CoexpressionGSE12366_GC_VS_NAIVE_BCELL_DN

CHD2 PSTPIP1 BTN3A2 BTN3A1 BTN3A3 MACF1 ARAP2

1.67e-041951557M3170
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

STARD13 AMPH SUPT20H KAT6A MARCHF6 ZMYND8 TTK ZEB2 MACF1 PARN ACAP2 VPS13B ARAP2 SOS1 KPNA3

1.77e-0485615515M4500
CoexpressionGSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP

PCLO LIPJ RNF213 BTN3A2 BTN3A1 RBCK1 XRN1

1.77e-041971557M7545
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH1_UP

AKR1C1 TMEM168 CPQ PEX16 MACF1 HERC1 CAMTA1

1.77e-041971557M5378
CoexpressionEBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION

MYH1 MACF1 MYBPC1 MYBPC2

1.87e-04481554M16123
CoexpressionGSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_UP

HK3 GIMAP2 BTN3A2 MEFV BTN3A3 XRN1 KPNA3

1.89e-041991557M9306
CoexpressionGSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN

FLOT2 VRK2 PHB2 BTN3A2 BTN3A1 RBCK1 BTN3A3

1.89e-041991557M7645
CoexpressionGSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN

MARCHF6 NUF2 WNK1 TBL1XR1 ATP10D HERC1 VPS13B

1.89e-041991557M3070
CoexpressionMASSARWEH_TAMOXIFEN_RESISTANCE_UP

ANK3 DHRS3 PSTPIP2 ATXN1L WDR26 PITPNM1 SYNJ1 TRIM62 BZW1 PREX1 VPS13B ARAP2

1.90e-0458315512M17454
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_B

PCLO MARCHF6 AKR1C4 ITGA9 WNK1 TBL1XR1 AKR1C1 AKR1C2 NDUFS1 PPP1R10 AKR1C3 ANAPC5

1.93e-0458415512MM1080
CoexpressionGSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN

SEMA4D FLOT2 VRK2 DHRS3 MYO1H GOLIM4 PREX1

1.95e-042001557M7162
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN

FLOT2 ERCC6L NUF2 WDR26 ZNF106 AP2A2 VPS13B

1.95e-042001557M8485
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN

RNF213 PPP1R10 TMEM168 RASGEF1B ALDH1B1 ARAP2 KPNA3

1.95e-042001557M9837
CoexpressionGSE360_CTRL_VS_L_DONOVANI_MAC_UP

HK3 MARCHF6 BTN3A2 PPP1R10 GPC3 ALDH1B1 MYBPC2

1.95e-042001557M5157
CoexpressionGSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP

ANK3 TCP1 KAT6A NDUFS1 PPP1R10 KMT2D ALDH1B1

1.95e-042001557M5261
CoexpressionGSE3982_BASOPHIL_VS_TH2_UP

SUPT20H CLIP2 ZMYND8 PSTPIP2 ATP10D MACF1 ARAP2

1.95e-042001557M5566
CoexpressionDARWICHE_SQUAMOUS_CELL_CARCINOMA_DN

PABPC4 AKR1C4 NUF2 AKR1C1 AKR1C2 PEX16 AKR1C3

2.01e-042011557MM502
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_SCG3_POS_LYMPHATIC_ENDOTHELIAL_CELL

SEMA4D PCLO ZMYND8 FAM98A ITGA9 AKR1C1 AKR1C2 ATP10D MYO5C PITPNM1 PDGFD AKR1C3

2.63e-0460415512M45760
CoexpressionMULLIGHAN_MLL_SIGNATURE_2_DN

DHRS3 LAMC3 MYO5C BTN3A3 NUDT11 MACF1 CDH4 ARAP2

2.66e-042791558M16867
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

ANK3 PCLO PEG3 ZMYND8 NEB KMT2E AKR1C1 AKR1C2 KCNC1 SYNJ1 RASGEF1B HERC1 CAMTA1 SCIN CDH4 TARBP1 PDZRN4

3.07e-04110615517M39071
CoexpressionFAN_EMBRYONIC_CTX_ASTROCYTE_2

B4GAT1 CACHD1 SLITRK2 MACF1 ALDOC MYBPC1

3.17e-041541556M39034
CoexpressionRUIZ_TNC_TARGETS_UP

MARCHF6 TBL1XR1 WDR26 BTN3A2 COL18A1 BTN3A3

3.40e-041561556M988
CoexpressionVERHAAK_GLIOBLASTOMA_CLASSICAL

CLIP2 RBCK1 MYO5C CDH4 CDH6 ARAP2

4.02e-041611556M2121
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A

DHRS3 ENPP1 MYO1H CDHR5 AKR1C4 NCLN ITGA9 AKR1C1 AKR1C2 ZEB2 MYO5C ACAN XRN1 AKR1C3 EVI5L

4.27e-0493015515MM893
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DOCK8 RNF213 CHD2 KMT2E ZEB2 RASGEF1B XRN1 MACF1 SRRM2 ARAP2

2.40e-092001561012f1685ce8f218433068e090c9d839cd5a1910bf
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUPT20H PEG3 ZEB2 PPP1R10 ZNF106 XIRP2 XRN1 GOLIM4 MACF1

1.27e-081761569749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL26 CHD2 PPP1R10 ZNF106 RASGEF1B XRN1 MACF1 SRRM2 ARAP2

1.70e-081821569eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD2 PPP1R10 ZNF106 RASGEF1B XRN1 MACF1 SRRM2 ARAP2

2.79e-07183156828cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD2 PPP1R10 ZNF106 RASGEF1B XRN1 MACF1 SRRM2 ARAP2

2.79e-0718315683fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

KNTC1 DOCK8 RNF213 ZEB2 KMT2D NOMO2 SHPRH MACF1

3.03e-071851568a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

MARCHF6 RNF213 CHD2 ZEB2 PPP1R10 MACF1 HERC1 ARAP2

3.42e-071881568ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ANK3 KAT6A CHD2 KMT2E BTN3A2 BTN3A1 OXNAD1 MACF1

4.52e-0719515684bdedd924564a260841a9153604026b57487c83d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

SEMA4D AMPH ANK3 TCP1 KMT2E SVBP ALDOC CDH9

4.70e-071961568dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RNF213 KMT2E BTN3A2 BTN3A1 BTN3A3 MACF1 SRRM2 ARAP2

4.88e-071971568836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

HK3 DOCK8 RNF213 PSTPIP2 PSTPIP1 ZEB2 MEFV PREX1

4.88e-071971568a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

HK3 DOCK8 RNF213 PSTPIP2 PSTPIP1 ZEB2 MEFV PREX1

5.07e-071981568ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DHRS3 RNF213 BTN3A2 BTN3A1 BTN3A3 AKR1C3 MACF1 ARAP2

5.27e-071991568df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

DHRS3 RNF213 BTN3A2 BTN3A1 PDGFD AKR1C3 MACF1 ARAP2

5.27e-071991568e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DHRS3 RNF213 BTN3A2 BTN3A1 BTN3A3 AKR1C3 MACF1 ARAP2

5.27e-071991568ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DHRS3 RNF213 BTN3A2 BTN3A1 PDGFD AKR1C3 MACF1 ARAP2

5.27e-0719915685f914962e2572b0c6372465b81b7496fa663d93c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SEMA4D KAT6A RNF213 CHD2 MACF1 HERC1 ARAP2

2.45e-0617115672e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANK3 RNF213 CHD2 PPP1R10 MACF1 HERC1 ARAP2

3.57e-061811567f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 KAT6A ZEB2 PPP1R10 ZNF106 XRN1 MACF1

3.98e-0618415671154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

KNTC1 DOCK8 RNF213 ZEB2 NOMO2 SHPRH MACF1

4.27e-0618615678571956890fc9894d766ba294a28e376b4aba428
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 CACHD1 THSD7B ZEB2 ITIH5 CDH6 PDZRN4

4.42e-061871567ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 CACHD1 THSD7B ZEB2 ITIH5 CDH6 PDZRN4

4.42e-061871567530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DHRS3 RNF213 ZEB2 PDGFD AKR1C3 MACF1 BZW1

4.58e-0618815679abd78970bbe4ed03b59a83da63bbd334712f605
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DHRS3 RNF213 ZEB2 PDGFD AKR1C3 MACF1 BZW1

4.58e-0618815675ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP1 KAT6A KMT2E ITGA9 WDR26 ITIH5 MACF1

4.91e-061901567d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA4D ANK3 DOCK8 PSTPIP1 OXNAD1 PREX1 ARAP2

5.08e-0619115675a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellbackground-Cholangiocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 WNT7B AKR1C1 ITIH5 PDGFD RASGEF1B CDH6

5.08e-06191156799aa8d685767a72bef9f05e7cc8913126a048c39
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

DHRS3 DOCK8 AKR1C1 AKR1C2 ITIH5 AKR1C3 HEATR5B

5.08e-061911567a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 RNF213 MACF1 PABPC1L HERC1 VPS13B ARAP2

5.44e-0619315679337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 WNT7B PCLO HUNK ITIH5 PDGFD CDH6

5.44e-0619315679152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS3 CTRC ITGA9 ITIH5 MYO5C COL18A1 PDGFD

5.44e-061931567c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCellAdult-Immune-monocyte-D122|Adult / Lineage, Cell type, age group and donor

AMPH HK3 DOCK8 PSTPIP2 PSTPIP1 ZEB2 PREX1

6.02e-06196156716b0acb6157534938ca83d4e909471e33a7d3c52
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

BTN3A2 BTN3A1 RBCK1 RASGEF1B XRN1 TARBP1 ARAP2

6.02e-06196156779632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

HK3 DOCK8 RNF213 PSTPIP2 ZEB2 RASGEF1B PREX1

6.22e-061971567e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

RNF213 BTN3A2 BTN3A1 BTN3A3 PDGFD MACF1 ARAP2

6.22e-061971567d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AMPH ANK3 PCLO PEG3 SPTBN4 HERC1 TARBP1

6.43e-0619815670ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 RNF213 CHD2 MACF1 HERC1 VPS13B ARAP2

6.65e-061991567f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DHRS3 ADGRV1 ZEB2 COL18A1 SLITRK2 PREX1 CDH6

6.65e-061991567f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

ANK3 GIMAP2 RNF213 BTN3A2 RBCK1 XRN1 TARBP1

6.65e-061991567056a0538ca5e825ae6195b4c76c208708a014533
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 ANK3 TBL1XR1 RASGEF1B HERC1 VPS13B SOS1

6.65e-06199156794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA4D DOCK8 RNF213 BTN3A2 ZEB2 PDGFD PREX1

6.65e-061991567eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ANK3 PCLO MARCHF6 AKR1C1 AKR1C2 ZEB2 SVBP

6.87e-0620015671decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellVE|World / Condition, Cell_class and T cell subcluster

SEMA4D RNF213 RBCK1 XRN1 MACF1 SRRM2 ARAP2

6.87e-0620015678ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

RNF213 BTN3A2 BTN3A1 BTN3A3 AKR1C3 MACF1 ARAP2

6.87e-0620015672281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

RNF213 BTN3A2 BTN3A1 BTN3A3 PDGFD MACF1 ARAP2

6.87e-062001567f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RNF213 CHD2 ZEB2 KMT2D MACF1 ARAP2

1.33e-05147156694998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ENPP1 RNF213 BTN3A1 ACAN MACF1 ARAP2

1.87e-051561566afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 DHRS3 CACHD1 ITGA9 AKR1C1 GPC3

1.94e-0515715666ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4D ERCC6L PSTPIP2 MEFV B4GALT5 PREX1

2.01e-051581566b35bab2b93d0af821bfae18a358eb7dddaf3860f
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4D ERCC6L PSTPIP2 MEFV B4GALT5 PREX1

2.01e-0515815667bd4a64a610eb1cbcd3d07ea5258a55107cf6c00
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 NEB TRIM62 MED12L VPS13B ARAP2

2.39e-051631566e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 NEB TRIM62 MED12L VPS13B ARAP2

2.39e-051631566ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 NEB TRIM62 MED12L VPS13B ARAP2

2.39e-051631566ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VRK2 HK3 MEFV ZNF630 XRN1 CDH4

2.74e-051671566a54b8e03987a7b067173121902e1811a3d003692
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnr.Rps24_(Rps24)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RPL26 ERCC6L WNK1 MYO5C MYBPC2

2.85e-051011565c075aa59acf333b05b6533b8172dc0c5c31b6ed3
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnr.Rps24_(Rps24)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RPL26 ERCC6L WNK1 MYO5C MYBPC2

2.85e-051011565be1c3034c2ebe64b7dd7a9b31ea43336ea1eeb73
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RPL26 ERCC6L WNK1 MYO5C MYBPC2

2.85e-0510115658ce6ebda05081dbd7db891e5da8af9cc7d4beacb
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRS2 ITIH5 GPC3 AP2A2 ALDH1B1 SOS1

3.03e-0517015668465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH GPC3 ACAN ALDOC CDH6 PDZRN4

3.13e-0517115664ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

DOCK8 ITIH5 COL18A1 ACAN CDH6 PDZRN4

3.13e-051711566e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D RNF213 NEB FANCM BTN3A2 ZEB2

3.23e-051721566f3c16a62eba1ed190318beee131c71c5150b266a
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DOCK8 PSTPIP1 PDGFD PREX1 ARAP2

3.45e-05174156661aa89b56ebda0eba1ba675d5f036992967f670f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 NEB XIRP2 UCP3 MYBPC1 MYBPC2

3.45e-0517415664a6e04b4f12b87c15fa1409989cbe32c43736369
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF213 BTN3A1 COL18A1 XRN1 OXNAD1 TARBP1

3.56e-05175156697616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L PCLO CACHD1 ADGRV1 MYO5C SCIN

3.56e-051751566fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L PCLO CACHD1 ADGRV1 MYO5C SCIN

3.56e-05175156636c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

ANK3 PCLO HUNK RASGEF1B CDH6 CDH9

3.68e-05176156636f77d878a53b30465b0dea8333a3865dba75613
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

AMPH WNT7B HUNK ITIH5 PDGFD CDH6

3.92e-05178156651c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CYP27C1 CACHD1 AKR1C1 AKR1C2 CDH6 PDZRN4

4.30e-051811566b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL18A1 SLITRK2 PREX1 CDH6 ARAP2 PDZRN4

4.43e-051821566bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 SLITRK2 PREX1 CDH6 ARAP2 PDZRN4

4.43e-051821566b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 KAT6A PSTPIP2 ZEB2 XRN1 MACF1

4.43e-051821566f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 SLITRK2 PREX1 CDH6 ARAP2 PDZRN4

4.43e-051821566f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 NEB XIRP2 UCP3 MYBPC1 MYBPC2

4.43e-051821566edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZEB2 ITIH5 COL18A1 SLITRK2 CDH4 CDH6

4.57e-051831566547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 PCLO ADGRV1 NEB SLITRK2 XIRP2

4.71e-0518415662cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 PCLO ADGRV1 NEB SLITRK2 XIRP2

4.71e-051841566ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS3 WNT7B COL18A1 PDGFD ALDOC CDH6

4.71e-05184156610706441e7695212f95689414f31e8082b5eaf0a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 PCLO ADGRV1 NEB SLITRK2 XIRP2

4.71e-0518415662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS3 WNT7B COL18A1 PDGFD ALDOC CDH6

4.71e-0518415664bb0976a75126ad2b3deb5d2229f0716fafe200e
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

ANK3 KMT2E AP2B1 EPC1 SVBP SRRM2

4.86e-051851566857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ANK3 CYP27C1 CACHD1 ADGRV1 ITGA9 MYO5C

4.86e-051851566cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 KAT6A ZEB2 ZNF106 XRN1 MACF1

4.86e-0518515667adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 SLITRK2 PREX1 CDH6 ARAP2 PDZRN4

4.86e-051851566a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STARD13 ZEB2 ITIH5 COL18A1 SLITRK2 CDH6

4.86e-051851566dd17025d8c423aa0a451ac7f1f301c93528e0229
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 NEB XIRP2 UCP3 MYBPC1 MYBPC2

4.86e-0518515669245c322aae8bb9065d50dada198a5ee143a3444
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK3 PCLO HUNK SCIN CDH6 CDH9

5.16e-051871566d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DHRS3 ZMYND8 PHB2 CACHD1 GPC3 EPC1

5.31e-051881566bcfc426b60d8e5a23a2360bfb68b32868fec9fbf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DHRS3 RNF213 ZEB2 PDGFD AKR1C3 MACF1

5.31e-051881566f7dc29dfec68236883469e848be5db34f5526d6b
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NIPSNAP1 NUF2 MYZAP TTK THOP1 SH3BP5L

5.31e-05188156615146fd2c5592ea84d20b1fdd172b39cd60b5bed
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 ZMYND8 CACHD1 HUNK ITGA9 PDZRN4

5.31e-051881566b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

LAMC3 COL18A1 PXDNL ACAN SCIN CDH6

5.47e-0518915669c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 NEB XIRP2 UCP3 MYBPC1 MYBPC2

5.47e-051891566d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ANK3 DHRS3 CACHD1 ADGRV1 AKR1C1 MYO5C

5.47e-05189156684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF213 BTN3A1 ZEB2 XRN1 MACF1 ARAP2

5.63e-051901566d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2C DOCK8 ZEB2 ITIH5 CDH6 PDZRN4

5.63e-0519015665681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

STARD13 COL18A1 PREX1 CDH6 ARAP2 PDZRN4

5.63e-0519015664a777d8aa19cadd3b61b023772df142421a89113
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 ZEB2 ITIH5 CPQ XRN1 SRRM2

5.80e-0519115667d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DHRS3 DOCK8 ENPP1 PEG3 ACAN SCIN

5.80e-051911566273c4a757292a9301de0eaeacdec91c9866be229
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DHRS3 DOCK8 ENPP1 PEG3 ACAN SCIN

5.80e-051911566f9a46956778a8773d6656340ecf5d218376d79c2
ComputationalNeighborhood of TTN

MYH1 NEB MYBPC1 MYBPC2

1.17e-04261074GNF2_TTN
ComputationalNeighborhood of CASP8

SEMA4D BTN3A2 BTN3A1 BTN3A3

1.37e-04271074GNF2_CASP8
ComputationalNeighborhood of SNRK

SEMA4D BTN3A2 BTN3A1 BTN3A3

1.58e-04281074GNF2_SNRK
Drugcloxazolam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.96e-0941534ctd:C005522
DrugPregnanes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.96e-0941534ctd:D011278
Drugtetralol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.96e-0941534ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.96e-0941534ctd:C018156
DrugHydroxysteroids

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.75e-0951534ctd:D006914
Drugcresolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.75e-0951534ctd:C010092
DrugMedazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.91e-0861534ctd:D008472
DrugNitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.34e-0781534ctd:D009567
Drug4-hydroxybenzoic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.41e-0791534ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.41e-0791534ctd:D004092
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

2.98e-0731533ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

2.98e-0731533ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

2.98e-0731533ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

2.98e-0731533ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

2.98e-0731533ctd:C530610
Drugoctyl gallate

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.99e-07101534ctd:C016627
DrugDihydroxydihydrobenzopyrenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.24e-07111534ctd:D004101
Drugchlordecone alcohol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.24e-07111534CID000013946
Drugp-nitrobenzaldehyde

FRS2 AKR1C4 AKR1C1 AKR1C3 ALDH1B1 ALDOC

8.11e-07481536CID000000541
DrugPhenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.31e-07121534ctd:D020113
Drugtetrahydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

1.18e-0641533ctd:C009413
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

1.18e-0641533ctd:C010969
DrugDBD-H

AKR1C4 AKR1C1 AKR1C3

1.18e-0641533CID000131382
DrugDMBA-3,4-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.34e-06131534CID000050096
Drugflunisolide

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.34e-06131534ctd:C007734
Drug5-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.86e-06141534ctd:D043582
Drug1-acenaphthenol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.86e-06141534CID000022750
DrugMeclofenamic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.86e-06141534ctd:D008469
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

2.95e-0651533CID000257630
DrugAC1L93E5

AKR1C4 AKR1C1 AKR1C3

5.86e-0661533CID000412383
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

5.86e-0661533ctd:D004949
Drug3-hydroxyhexobarbital

AKR1C4 AKR1C2 AKR1C3

5.86e-0661533CID000439898
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

5.86e-0661533ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

5.86e-0661533ctd:C023723
Drugoxcarbazepine

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.02e-06191534ctd:C036006
DrugFlucytosine [2022-85-7]; Down 200; 31uM; HL60; HT_HG-U133A

PCLO FRS2 NEB BTN3A1 MYO5C PITPNM1 PDGFD ALDH1B1 VPS13B

8.37e-0619915393073_DN
Drugbenzo(a)pyrene-7,8-dione

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.74e-06201534ctd:C076588
DrugChrysenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.74e-06201534ctd:D002911
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1C3

1.02e-0571533ctd:C117714
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

1.02e-0571533ctd:C020549
DrugFlunitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-05211534ctd:D005445
DrugDutasteride

AKR1C1 AKR1C2 AKR1C3 SOS1

1.07e-05211534ctd:D000068538
Drugbenzene dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.31e-05221534CID000000418
Drug2-cyclohexen-1-ol

AKR1C4 AKR1C2 AKR1C3

1.63e-0581533CID000013198
DrugGlycyrrhetinic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.88e-05241534ctd:D006034
Drug9,10-phenanthrenequinone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.22e-05251534ctd:C005399
DrugPregnanolone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.22e-05251534ctd:D011280
Drugtestosterone enanthate

ANK3 ENPP1 WNK1 AKR1C1 AKR1C2 AP2B1 AKR1C3 GOLIM4 MACF1 ALDH1B1 SRRM2 ANAPC5 SOS1 WDR48

3.52e-0557515314ctd:C004648
Drug1,2-dihydroxynaphthalene

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDOC

4.05e-05571535CID000011318
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

4.49e-0521532ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

4.49e-0521532DB07768
Drugbaccharin

AKR1C2 AKR1C3

4.49e-0521532ctd:C012764
Drugbenzo(a)pyrene 7,8-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.36e-05311534ctd:C017228
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; HL60; HG-U133A

FPGS SRP19 NCLN AP2B1 ACAN MACF1 ALDH1B1 TARBP1

5.99e-0519815382002_DN
DrugTocainide hydrochloride; Up 200; 17.4uM; HL60; HT_HG-U133A

ANK3 B4GAT1 FRS2 TRIM62 SMARCD1 ALDH1B1 SRRM2 SCIN

6.20e-0519915382931_UP
Drugfenamic acid

AKR1C1 AKR1C2 AKR1C3

6.26e-05121533ctd:C001209
DrugEthosuximide [77-67-8]; Down 200; 28.4uM; PC3; HT_HG-U133A

STARD13 WNT7B BTN3A1 PITPNM1 TRIM62 PEX16 SMARCD1 SRRM2

6.43e-0520015387308_DN
DrugEpivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

PCLO SRP19 PITPNM1 GPC3 SYNJ1 CPQ CDH6 VPS13B

6.43e-0520015386838_UP
DrugFurazolidone [67-45-8]; Up 200; 17.8uM; HL60; HT_HG-U133A

ANK3 ENPP1 CDHR5 RBCK1 KMT2D KCNC1 PEX16 SCIN

6.43e-0520015383019_UP
Drug4-formyl-benzoate

AKR1C4 AKR1C1 AKR1C2

8.10e-05131533CID000012088
DrugDydrogesterone

AKR1C1 AKR1C2 AKR1C3

1.03e-04141533ctd:D004394
Drug6-.beta.-Naltrexol

AKR1C4 AKR1C1 AKR1C2

1.03e-04141533CID000631219
Drug5 beta-pregnane-3,20-dione

CTRC AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.25e-04721535CID000092745
Drugdrospirenone

AKR1C4 AKR1C1 AKR1C2

1.28e-04151533ctd:C035144
DrugMefenamic Acid

NCLN AKR1C1 AKR1C2 AKR1C3

1.34e-04391534ctd:D008528
Drug20 alpha-dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.48e-04401534CID000008956
Drug9-cis-retinal

AKR1C4 AKR1C1 AKR1C3

1.56e-04161533ctd:C031390
Drugo-quinone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.64e-04411534CID000011421
Drugbu-b

SRP19 ADGRV1 TTK GPC3 REV1

1.72e-04771535CID000351065
Drugbenzo(a)pyrene-1,6-quinone

AKR1C1 AKR1C2 AKR1C3

1.89e-04171533ctd:C030233
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

2.25e-04181533CID000002816
DrugRuthenium Compounds

AKR1C1 AKR1C2 AKR1C3

2.25e-04181533ctd:D017975
Drugbenzo(a)pyrene-3,6-quinone

AKR1C1 AKR1C2 AKR1C3

2.25e-04181533ctd:C018003
Drug1,10-phenanthroline

AKR1C4 AKR1C1 AKR1C2 AKR1C3 ALDOC

2.31e-04821535ctd:C025205
DrugFlufenamic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.36e-04451534ctd:D005439
Drugnaphthalene-1,2-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.36e-04451534CID000000362
DrugAC1L8ZBW

AKR1C4 AKR1C1 AKR1C2

2.66e-04191533CID000435356
DrugN,N-Dibenzylethanolamine

WNK1 PEX16

2.67e-0441532CID000022656
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

1.42e-0731553C0027661
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

1.41e-0651553C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

1.41e-0651553C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

1.41e-0651553C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

1.41e-0651553C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

1.41e-0651553C2930619
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

4.90e-0671553C0036875
DiseaseMALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE

AKR1C4 AKR1C2

2.74e-0521552C1839840
Disease46,XY disorder of sex development due to testicular 17,20-desmolase deficiency

AKR1C4 AKR1C2

2.74e-0521552cv:C1839840
Disease46,XY sex reversal 8 (is_implicated_in)

AKR1C4 AKR1C2

2.74e-0521552DOID:0111773 (is_implicated_in)
Disease46,XY SEX REVERSAL 8

AKR1C4 AKR1C2

2.74e-0521552614279
Diseasecognitive function measurement

PPP4R1 KNTC1 SEMA4D FLOT2 VRK2 LAMC3 CHD2 THSD7B KMT2E BTN3A2 SNURFL KMT2D MED12L BZW1 CDH4 PREX1 CDH9 MYBPC2 SOS1 REV1

6.61e-05143415520EFO_0008354
Diseaseresponse to methotrexate

AKR1C1 AKR1C2 CDH9

7.57e-05161553GO_0031427
DiseaseFetal Alcohol Syndrome

ANK3 ERCC6L SLITRK2

9.16e-05171553C0015923
Diseasemigraine disorder

ZMYND8 RNF213 ZEB2 ZNF106 CPQ MACF1 CAMTA1 CDH4 PDZRN4

1.20e-043571559MONDO_0005277
DiseaseAcne Vulgaris

PSTPIP1 MEFV

1.63e-0441552C0001144
DiseaseAcne

PSTPIP1 MEFV

1.63e-0441552C0702166
DiseasePyoderma Gangrenosum

PSTPIP1 MEFV

1.63e-0441552C0085652
Diseaseplatelet component distribution width

SUPT20H DOCK8 ZMYND8 WNK1 COL18A1 KIF9 AP2B1 EPC1 MACF1 HERC1 CAMTA1 PREX1 MYBPC1

1.86e-0475515513EFO_0007984
DiseaseHeadache

MYO1H RNF213 MACF1 SOS1

3.64e-04641554HP_0002315
Diseaseglucagon measurement, glucose tolerance test

MACF1 HERC1

4.06e-0461552EFO_0004307, EFO_0008463
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

4.06e-0461552EFO_0800552
DiseaseHidradenitis Suppurativa

PSTPIP1 MEFV

5.66e-0471552C0162836
Diseaseresponse to 5-fluorouracil, response to antineoplastic agent

SCIN ARAP2

5.66e-0471552GO_0036275, GO_0097327
Diseasecentral serous retinopathy

WNK1 PREX1

7.52e-0481552EFO_0009784
Diseaseblindness (implicated_via_orthology)

RPL26 RPL26L1

7.52e-0481552DOID:1432 (implicated_via_orthology)
DiseaseSclerocystic Ovaries

TTK AKR1C1 AKR1C2 SPTBN4 AKR1C3

1.00e-031441555C1136382
DiseasePolycystic Ovary Syndrome

TTK AKR1C1 AKR1C2 SPTBN4 AKR1C3

1.00e-031441555C0032460
DiseaseInherited obesity

ENPP1 UCP3

1.20e-03101552cv:C4054476
DiseaseObesity

ENPP1 UCP3

1.20e-03101552cv:C0028754
DiseaseOBESITY

ENPP1 UCP3

1.20e-03101552601665
Diseaseprostate cancer (is_marker_for)

KMT2E KMT2D AKR1C3 PREX1 SOS1

1.43e-031561555DOID:10283 (is_marker_for)
DiseaseNeurodevelopmental Disorders

DOCK8 CHD2 KMT2E TBL1XR1

1.49e-03931554C1535926
DiseaseMalignant neoplasm of breast

MYH1 HK3 B4GAT1 TCP1 ITGA9 WNK1 BTN3A2 ZEB2 KMT2D GOLIM4 SMARCD1 MACF1 ANAPC5 VPS13B

1.64e-03107415514C0006142
Diseaseanti-Epstein Barr virus antibody measurement

BTN3A2 MED12L

1.75e-03121552EFO_0009273
DiseaseFetal Alcohol Spectrum Disorders

ANK3 SLITRK2

2.06e-03131552C2985290
DiseaseParkinson's disease symptom measurement

PDGFD RASGEF1B XRN1

2.07e-03481553EFO_0600011
Diseasemyopathy (implicated_via_orthology)

MYH1 COL18A1 MYBPC2

2.07e-03481553DOID:423 (implicated_via_orthology)
Diseaseforced expiratory volume, response to bronchodilator

AMPH DOCK8 ADGRV1 SERPINA2 KIF2B ALDH1B1 CAMTA1 PREX1

2.52e-034451558EFO_0004314, GO_0097366
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYBPC1

2.75e-03151552DOID:0050646 (implicated_via_orthology)
Diseasepemphigus vulgaris

THSD7B PPP1R10

3.13e-03161552EFO_0004719
Diseasefourth ventricle volume measurement

ATP10D XIRP2

3.13e-03161552EFO_0010303
Diseaselevel of Phosphatidylcholine (18:0_20:3) in blood serum

NOMO1 PARN

3.13e-03161552OBA_2045093
DiseaseFamilial Progressive Myoclonic Epilepsy

CHD2 KCNC1

3.54e-03171552C0751777
DiseaseAtypical Inclusion-Body Disease

CHD2 KCNC1

3.54e-03171552C0751776
DiseaseMyoclonic Epilepsies, Progressive

CHD2 KCNC1

3.54e-03171552C0751778
DiseaseBiotin-Responsive Encephalopathy

CHD2 KCNC1

3.54e-03171552C0751780
DiseaseMay-White Syndrome

CHD2 KCNC1

3.54e-03171552C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

CHD2 KCNC1

3.54e-03171552C0751781
Diseaseimmature platelet measurement

PPP4R1 DOCK8 ZMYND8 AP2B1

3.64e-031191554EFO_0803541
DiseaseAction Myoclonus-Renal Failure Syndrome

CHD2 KCNC1

3.97e-03181552C0751779
DiseaseSARS-CoV-2 antibody measurement, response to COVID-19 vaccine

TBL1XR1 CAMTA1 MYBPC1

4.29e-03621553EFO_0803360, EFO_0803362
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

NOMO1 PARN

4.42e-03191552OBA_2045199
Diseaseenergy expenditure measurement

THSD7B KCNC1

4.90e-03201552EFO_0008005
Diseasecortical surface area measurement

SEMA4D VRK2 ANK3 LAMC3 CACHD1 ADGRV1 PSTPIP1 ITIH5 ZNF106 PDGFD RASGEF1B XRN1 MACF1 SOS1 PDZRN4

4.93e-03134515515EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
VVLAKSYNEQRIREN

AKR1C4

266

P17516
ENYVIKRELAVVRQQ

EVI5L

411

Q96CN4
QRAISAQQVYGEKRD

EPC1

56

Q9H2F5
VVYFRQEQEEEGQKR

ACOT7L

101

Q6ZUV0
AKVQDYRQAQVERLE

CIBAR2

76

Q6ZTR7
YRQAQVERLETKVVN

CIBAR2

81

Q6ZTR7
QQEVAAAVIQRCYRK

CAMTA1

1546

Q9Y6Y1
EVQQTVYREIVKNLG

CYP27C1

371

Q4G0S4
RRASEARGKIVVYNQ

CPQ

161

Q9Y646
NNVYTIAKRNVEGQD

AP2B1

871

P63010
SLRQVVNVYADGKEV

BTN3A3

71

O00478
LSEYVRNQQTIGARK

BZW1

241

Q7L1Q6
SLRQVVNVYADGKEV

BTN3A1

71

O00481
AQQETQKAALRYERA

SH3BP5L

126

Q7L8J4
NKNELVQLYQVGEVR

B4GAT1

271

O43505
VVLAKSYNEQRIRQN

AKR1C3

266

P42330
QIGVENTEENRRLYR

ALDOC

46

P09972
QVDKEQFERVLGYIQ

ALDH1B1

361

P30837
YELQGAREQQKIRQE

FLOT2

241

Q14254
DRVNVENQVLKSGYT

ADGRV1

746

Q8WXG9
DVVNRNKQVVEASYT

CACHD1

101

Q5VU97
YERLQRAEAQGKQEV

CLIP2

766

Q9UDT6
RVQGDNKFEVVTTQR

ARAP2

536

Q8WZ64
YGIAQRQRQEEVQEV

C6orf163

221

Q5TEZ5
GNDVINRVYEANVEK

ACAP2

471

Q15057
KGQQADLARYSVTQV

CDHR5

326

Q9HBB8
NVRTIGAQVYEQVLR

B4GALT5

56

O43286
SNLKQRQVVRGYAEQ

ATP10D

216

Q9P241
QIVINRDDVQGYAAK

AP2A2

466

O94973
EYVQNFKRQEAEGTR

AMPH

41

P49418
LQGEVQLTARRYQEK

PDZRN4

181

Q6ZMN7
IQRDIEYFVNQRKTG

PSTPIP2

261

Q9H939
RENVGIYNLSKGVNR

NOMO3

611

P69849
QYQKALRQSAGAVVI

NCLN

96

Q969V3
QLREQYDEKRSQANG

PARN

141

O95453
IEGVYRKAVVLQAQN

ANAPC5

541

Q9UJX4
NSVIYGVRTKQIRAQ

OR52E1

286

Q8NGJ3
RAQAEERYGKELVQI

PSTPIP1

46

O43586
EQLKQERISRYQGVN

PABPC4

281

Q13310
RENVGIYNLSKGVNR

NOMO2

611

Q5JPE7
TISGRKDQVEYLVQQ

KPNA3

396

O00505
RARIYEVEQQIKQRG

MED12L

421

Q86YW9
RYDVNREQSIGDIQV

ITIH5

261

Q86UX2
EGNAYIDLRVVKQTV

LRIT2

361

A6NDA9
QELVERYSQKAARNG

GPC3

426

P51654
AGEEEALRQYQQRKQ

RBCK1

241

Q9BYM8
RTDNNKNLAQRVVVY

LIPJ

36

Q5W064
EVQRVVGALASQDYR

ATXN1L

336

P0C7T5
NVRQSLGNSQREYEK

FAM91A1

21

Q658Y4
EGREERIYNQSQSNK

FANCM

591

Q8IYD8
YQDGIRAAKRNIQIE

HERC1

1706

Q15751
GQDQFVRIYDQRKID

DCAF8L2

386

P0C7V8
RRDETIQVKGNGYVQ

PDGFD

51

Q9GZP0
RQITANEVYGKQISA

PCLO

2756

Q9Y6V0
QEKRGAVYERVTTIN

NUF2

381

Q9BZD4
EQEELYVRVQNGFRK

COL18A1

1471

P39060
YVRVQNGFRKVQLEA

COL18A1

1476

P39060
RENVGIYNLSKGVNR

NOMO1

611

Q15155
QYSEGVQREAQRIAL

KMT2E

291

Q8IZD2
NEQYKLVSDTIGQRV

MACF1

1776

O94854
KTVIEQVYANGIRNI

MARCHF6

786

O60337
ENRRTYQNLVIEKDG

KNTC1

131

P50748
LRKYAEERNGVNVVS

ENPP1

781

P22413
NAEVVTAYRGKKRQE

MYH1

136

P12882
GVFEQNQDRKHRTYV

NUDT11

81

Q96G61
VGQIRKAYDTRVSQD

MEFV

491

O15553
QIAEINSQVRRYLEG

KIF9

391

Q9HAQ2
LYAGRAQKRVERQNE

PABPC1L

261

Q4VXU2
IASGEEQTYRKNVQQ

RASGEF1B

141

Q0VAM2
IRRQGAYNIDVVAVV

HK3

206

P52790
REYTAAVEAKQVAQQ

PHB2

191

Q99623
KRESVIQQRVYEGNA

PEG3

356

Q9GZU2
RQIEAGYKQEVEQLR

MTMR4

1026

Q9NYA4
GYKQEVEQLRRQVRE

MTMR4

1031

Q9NYA4
EGRVRVNSAYQDKVS

ACAN

91

P16112
QGYNTAREKPTREVQ

GOLIM4

266

O00461
REQANKRNGYEIGTI

OXNAD1

196

Q96HP4
IRDEGQVTVYINRGN

ITGA9

331

Q13797
YRKNNISVFEVDGNV

KAT6A

571

Q92794
TVYQEARKIVGAELQ

PXDNL

996

A1KZ92
QDKIYVGEDARNVTV

PXDNL

1341

A1KZ92
EQINNYVEKRTGRKV

SERPINA2

181

P20848
QQIVRAAQDYLQEKR

HEATR5B

1666

Q9P2D3
KTEIENVRNGTQVRY

KCNC1

221

P48547
TYRVAVGKNNLEVED

CTRC

81

Q99895
NKRLITADQREYQQE

DOCK8

2031

Q8NF50
GRYTSQDQQAAQRVK

GIMAP2

116

Q9UG22
SELNKQYQIVERVIA

CHD2

371

O14647
RVPSEVQQRYANVEK

DCDC2C

221

A8MYV0
YVNTTGVQEERKNRT

FRS2

196

Q8WU20
DTYVTKNLRREGQIQ

HUNK

101

P57058
VTVAAGLDREKVQQY

CDH4

341

P55283
GLDREKVQQYTVIVQ

CDH4

346

P55283
VVRYLVQDGAQVEAK

ANK3

481

Q12955
SLRQVVNVYADGKEV

BTN3A2

71

P78410
QTNAGYLEQVKRQRG

FPGS

56

Q05932
RENREQYQVVIQAKD

CDH6

226

P55285
SQGTRYQTRQAVKAV

ZMYND8

856

Q9ULU4
RENREQYQVVIQAKD

CDH9

226

Q9ULB4
DVGNREEVYQTAKAV

DHRS3

96

O75911
IQEGIYVAIQRSDKR

KIF2B

26

Q8N4N8
AVDRVYRIGQKENVV

ERCC6L

566

Q2NKX8
YIERVQREKANGTTV

RPL26L1

81

Q9UNX3
RAIKYRQENQEAVGG

NIPSNAP1

206

Q9BPW8
NHEQSYVGKRSNRVV

PEX16

161

Q9Y5Y5
YVGKRSNRVVRTLQN

PEX16

166

Q9Y5Y5
VRGTQRAVGVQNYLE

PUSL1

31

Q8N0Z8
YVSKEQRLQAVQAAI

STARD13

761

Q9Y3M8
SAQQELKQRQRAEIY

SVBP

26

Q8N300
GYEEQQIQEKVATFR

SRRM2

81

Q9UQ35
VVRYLADQNNQVRKT

PPP4R1

136

Q8TF05
YSKVQQRRQELEQAL

SMARCD1

496

Q96GM5
VQYRGRVRVQLKQED

SRP19

76

P09132
EERQNIYKEVIAVQG

SYNJ1

876

O43426
YVNTEGRAQQTKVAV

NDUFS1

596

P28331
ERLKANQVATGIRYN

SCIN

186

Q9Y6U3
AINQAIANEYEVRRK

FAM98A

206

Q8NCA5
TLVDNIQRYVEDGKN

PREX1

1291

Q8TCU6
RRQNQDRINKTVLYG

SLITRK2

791

Q9H156
RVRNEITSNYKQQTG

SHPRH

1161

Q149N8
KEAVRYINENLIVNT

TCP1

126

P17987
EQAIREQRLYKQERG

TEN1

106

Q86WV5
KDVNYTQIVVDRTQA

SEMA4D

416

Q92854
RRKVAEITGEIQQYQ

SOS1

961

Q07889
VVQTRQQAYRDKLAQ

TBL1XR1

91

Q9BZK7
RYEKERQLNEAVGNV

AKAP3

826

O75969
VVLAKSYNEQRIRQN

AKR1C1

266

Q04828
VVLAKSYNEQRIRQN

AKR1C2

266

P52895
QEDIQKGDVSSVRYR

XIRP2

1201

A4UGR9
QTYIVGRAVRKLQAQ

PITPNM1

1141

O00562
SDVAEKLYIQQIVQR

RNF213

2586

Q63HN8
KYNAAVQVEVVRASR

WNT7B

231

P56706
ENQAVQTARLVQYRG

UCP3

46

P55916
RQNTAGRRKVQVSYV

WDR48

6

Q8TAF3
IRDEVEKYNRNGVNA

WDR48

21

Q8TAF3
ELKAAYDQRQRQGEN

REV1

1031

Q9UBZ9
RLSQLEGVNVERYKQ

VPS35

226

Q96QK1
YIERVQREKANGTTV

RPL26

81

P61254
IGSKTDAERVVNQYQ

SUPT20H

396

Q8NEM7
LTGRKYQINQNGEVR

XRN1

801

Q8IZH2
VEVQVKYRTAALSNQ

SNURFL

21

B1AK76
VRQLQEGAAQLRTVY

SPTBN4

1891

Q9H254
VRKINDQYIAVQGAE

TMEM168

556

Q9H0V1
DRYQGNQDRVLRQVT

ZNF630

126

Q2M218
DKYGQNESFARIQVR

TTK

101

P33981
VDGVRERLSEQQYNR

VPS13B

3941

Q7Z7G8
RVVAQYAQRNAKGGV

TTC37

1201

Q6PGP7
ERVIKTQYQSAQRAE

ERVK-19

486

Q9WJR5
TQYSGKQRTENVLRI

TARBP1

651

Q13395
QDRVLVRKYQGVTQG

WDR26

556

Q9H7D7
QNAAQIYRRVTSGVK

WNK1

426

Q9H4A3
GNATVKQSRYRIIIQ

THSD7B

756

Q9C0I4
KQSRYRIIIQEAANG

THSD7B

761

Q9C0I4
RRKNVVNYDNVVDTG

ZEB2

21

O60315
IEQTKRVYDQVGTQE

THOP1

41

P52888
QERYIQAEREKGILQ

PPP1R10

481

Q96QC0
QRYSQQLRKVQEGAQ

TRIM62

216

Q9BVG3
QRQENDKLGTVATYR

ZNF106

281

Q9H2Y7
EAAQESTRRRQKYQE

VRK2

391

Q86Y07
ANRREKIYEEQNRGI

KMT2D

5436

O14686
YQEVQAAQKALRTAV

LAMC3

1211

Q9Y6N6
LIEKSRVVYQNEGER

MYO1H

186

Q8N1T3
IQQYFRGQQTVRKAI

MYO5C

786

Q9NQX4
KQTYIRRVGEAVNLV

MYBPC1

846

Q00872
VVQEDRGRYQVITNG

MYBPC2

411

Q14324
VVYGVVRRSDQNQQK

MYZAP

71

P0CAP1
QRVKRNQENISSVLY

NEB

6326

P20929