Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	tau-protein kinase activity	TAOK2 SIK3 MARK4 MARK2	5.85e-05	22	197	4	GO:0050321
GeneOntologyMolecularFunction	ankyrin binding	OBSCN IQCJ-SCHIP1 PLEC SPTBN4	7.02e-05	23	197	4	GO:0030506
GeneOntologyMolecularFunction	cytoskeletal protein binding	SPTA1 APC2 OBSCN NOD2 TAOK2 SPTBN5 NF1 DST IQCJ-SCHIP1 JAKMIP1 PLEC AGBL1 UTRN BICD2 VEZT SPAG5 SPTBN4 KIFAP3 MARK4 MACF1 FHDC1 TRAK2 MARK2 MYO15A SMAD4	8.55e-05	1099	197	25	GO:0008092
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RASGRP4 OBSCN DOCK6 RGL2 RIC1 ARHGEF28 SH2D3A MADD ARHGEF3 RINL	1.03e-04	231	197	10	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RASGRP4 OBSCN NF1 SGSM2 SGSM3 DOCK6 RGL2 RIC1 AGAP1 ARHGEF28 SH2D3A MADD ARHGEF3 ARHGAP18 RINL	1.61e-04	507	197	15	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RASGRP4 OBSCN NF1 SGSM2 SGSM3 DOCK6 RGL2 RIC1 AGAP1 ARHGEF28 SH2D3A MADD ARHGEF3 ARHGAP18 RINL	1.61e-04	507	197	15	GO:0030695
GeneOntologyMolecularFunction	mono-olein transacylation activity	PNPLA2 PNPLA3	2.89e-04	3	197	2	GO:0051264
GeneOntologyMolecularFunction	diolein transacylation activity	PNPLA2 PNPLA3	2.89e-04	3	197	2	GO:0051265
GeneOntologyBiologicalProcess	intracellular transport	MKKS ABCA2 AP5S1 VPS13C IFT172 TTC21A BARD1 TSC1 FHIP1B TRIP11 CDR2L SPTBN5 NF1 DST MDN1 SGSM2 PEX16 IFT80 RIC1 BICD2 WASHC4 PPFIA2 ATL3 SPG11 THOC2 LEP HPS3 PEX26 MADD SPAG5 KIFAP3 TRAK2 TRIM37 PCNT	2.45e-06	1496	199	34	GO:0046907
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	MKKS SPTA1 APC2 TSC1 TAOK2 SPTBN5 IQCJ-SCHIP1 BICD2 CARMIL2 WASHC4 CIT SPAG5 SPTBN4 RNH1 KANK3 MARK2 ARHGAP18 TRIM37 SMAD4	3.63e-06	579	199	19	GO:0051493
GeneOntologyBiologicalProcess	microtubule-based process	MKKS CENPA IFT172 TTC21A APC2 CNTROB SPICE1 CDR2L DST TTC12 IFT80 BICD2 ARMC12 DYNLT2 SPG11 SIK3 MADD SPAG5 KIFAP3 MARK4 MACF1 TRAK2 MARK2 TRIM37 SEPTIN12 PCNT	1.14e-05	1058	199	26	GO:0007017
GeneOntologyBiologicalProcess	cytoskeleton-dependent intracellular transport	IFT172 TTC21A CDR2L DST IFT80 BICD2 PPFIA2 SPG11 MADD KIFAP3 TRAK2	1.24e-05	225	199	11	GO:0030705
GeneOntologyBiologicalProcess	regulation of organelle organization	MKKS ATR VPS13C SPTA1 LRSAM1 APC2 TSC1 CNTROB SPICE1 NOD2 TAOK2 SPTBN5 NCAPG IQCJ-SCHIP1 SGSM3 BICD2 CARMIL2 WASHC4 ATL3 TEX14 CIT SPAG5 SPTBN4 RNH1 KANK3 MARK4 MARK2 ARHGAP18 TRIM37 SMAD4	1.43e-05	1342	199	30	GO:0033043
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	MKKS SPTA1 APC2 SPTBN5 IQCJ-SCHIP1 CARMIL2 SPTBN4 KANK3 TRIM37 SMAD4	1.97e-05	194	199	10	GO:0051494
GeneOntologyBiologicalProcess	transport along microtubule	IFT172 TTC21A CDR2L DST IFT80 BICD2 SPG11 MADD KIFAP3 TRAK2	2.25e-05	197	199	10	GO:0010970
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	MKKS SPTA1 SPTBN5 CARMIL2 SPTBN4 KANK3	8.66e-05	75	199	6	GO:0030837
GeneOntologyBiologicalProcess	microtubule-based movement	MKKS IFT172 TTC21A CDR2L DST TTC12 IFT80 BICD2 ARMC12 DYNLT2 SPG11 MADD KIFAP3 TRAK2 SEPTIN12	9.32e-05	493	199	15	GO:0007018
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	MKKS SPTA1 TSC1 TAOK2 SPTBN5 CARMIL2 WASHC4 CIT SPTBN4 RNH1 KANK3 ARHGAP18 SMAD4	9.63e-05	384	199	13	GO:0032956
GeneOntologyCellularComponent	spectrin	SPTA1 SPTBN5 SPTBN4	6.54e-05	9	196	3	GO:0008091
GeneOntologyCellularComponent	ATR-ATRIP complex	ATR ATRIP	8.75e-05	2	196	2	GO:0070310
Domain	Leu-rich_rpt	MFHAS1 LRSAM1 NYX NOD2 LRRIQ1 PPP1R37 FLRT2 NLRC3 NLRP13 GP5 LRRC8E CARMIL2 VASN LRRC40 LRRC58 RNH1 LRMDA	3.65e-09	271	194	17	IPR001611
Domain	-	MFHAS1 LRSAM1 NAIP NYX NOD2 LRRIQ1 PPP1R37 FLRT2 NLRC3 NLRP13 GP5 LRRC8E CARMIL2 VASN LRRC40 LRRC58 RNH1 LRMDA	7.27e-09	321	194	18	3.80.10.10
Domain	L_dom-like	MFHAS1 LRSAM1 NAIP NYX NOD2 LRRIQ1 PPP1R37 FLRT2 NLRC3 NLRP13 GP5 LRRC8E CARMIL2 VASN LRRC40 LRRC58 RNH1 LRMDA	1.02e-08	328	194	18	IPR032675
Domain	Spectrin_repeat	SPTA1 SPTBN5 DST PLEC UTRN SPTBN4 MACF1	1.51e-08	29	194	7	IPR002017
Domain	SPEC	SPTA1 SPTBN5 DST PLEC UTRN SPTBN4 MACF1	3.16e-08	32	194	7	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTBN5 DST PLEC UTRN SPTBN4 MACF1	3.16e-08	32	194	7	IPR018159
Domain	ARM-type_fold	USP34 ATR IFT172 APC2 ITPR1 EFR3A NCAPG NF1 TTC12 BRAT1 AGBL1 ARMC12 WDFY4 KIFAP3 MROH1 PELP1 ARMC5	9.84e-08	339	194	17	IPR016024
Domain	Spectrin	SPTA1 SPTBN5 DST UTRN SPTBN4 MACF1	1.01e-07	23	194	6	PF00435
Domain	ACTININ_2	SPTBN5 DST PLEC UTRN SPTBN4 MACF1	1.01e-07	23	194	6	PS00020
Domain	ACTININ_1	SPTBN5 DST PLEC UTRN SPTBN4 MACF1	1.01e-07	23	194	6	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 DST PLEC UTRN SPTBN4 MACF1	1.01e-07	23	194	6	IPR001589
Domain	ARM-like	ATR APC2 EFR3A NCAPG NF1 TTC12 BRAT1 AGBL1 ARMC12 WDFY4 KIFAP3 MROH1 PELP1 ARMC5	9.29e-07	270	194	14	IPR011989
Domain	LRR_1	MFHAS1 LRSAM1 NYX LRRIQ1 FLRT2 GP5 LRRC8E VASN LRRC40 LRRC58 RNH1 LRMDA	3.22e-06	219	194	12	PF00560
Domain	-	ATR APC2 EFR3A NCAPG NF1 TTC12 BRAT1 ARMC12 WDFY4 KIFAP3 MROH1 ARMC5	3.71e-06	222	194	12	1.25.10.10
Domain	CH	SPTBN5 EHBP1L1 DST PLEC UTRN SPTBN4 MACF1	4.90e-06	65	194	7	SM00033
Domain	SAM_2	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	5.15e-06	43	194	6	PF07647
Domain	CH	SPTBN5 EHBP1L1 DST PLEC UTRN SPTBN4 MACF1	8.07e-06	70	194	7	PF00307
Domain	LRR	MFHAS1 LRSAM1 NOD2 LRRIQ1 PPP1R37 GP5 LRRC8E VASN LRRC40 LRRC58 LRMDA	8.45e-06	201	194	11	PS51450
Domain	-	SPTBN5 EHBP1L1 DST PLEC UTRN SPTBN4 MACF1	8.88e-06	71	194	7	1.10.418.10
Domain	CH	SPTBN5 EHBP1L1 DST PLEC UTRN SPTBN4 MACF1	1.07e-05	73	194	7	PS50021
Domain	CH-domain	SPTBN5 EHBP1L1 DST PLEC UTRN SPTBN4 MACF1	1.28e-05	75	194	7	IPR001715
Domain	LRR_TYP	MFHAS1 LRSAM1 NYX LRRIQ1 FLRT2 GP5 LRRC8E VASN LRRC40 LRRC58	1.66e-05	177	194	10	SM00369
Domain	Leu-rich_rpt_typical-subtyp	MFHAS1 LRSAM1 NYX LRRIQ1 FLRT2 GP5 LRRC8E VASN LRRC40 LRRC58	1.66e-05	177	194	10	IPR003591
Domain	-	DST PLEC MACF1	2.16e-05	6	194	3	3.90.1290.10
Domain	LRR_6	NOD2 PPP1R37 NLRC3 NLRP13 CARMIL2 RNH1	2.21e-05	55	194	6	PF13516
Domain	Plectin	DST PLEC MACF1	3.75e-05	7	194	3	PF00681
Domain	Plectin_repeat	DST PLEC MACF1	3.75e-05	7	194	3	IPR001101
Domain	PLEC	DST PLEC MACF1	3.75e-05	7	194	3	SM00250
Domain	LRR_8	MFHAS1 LRSAM1 NYX FLRT2 GP5 LRRC8E VASN LRRC40 LRRC58	7.66e-05	171	194	9	PF13855
Domain	NACHT	NAIP NOD2 NLRC3 NLRP13	8.56e-05	23	194	4	PS50837
Domain	NACHT_NTPase	NAIP NOD2 NLRC3 NLRP13	8.56e-05	23	194	4	IPR007111
Domain	ABC_A	ABCA2 ABCA13 ABCA7	2.27e-04	12	194	3	IPR026082
Domain	SAM	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	3.11e-04	88	194	6	SM00454
Domain	Laminin_IV_B	LAMB4 LAMB2	3.20e-04	3	194	2	IPR013015
Domain	LAMININ_IVB	LAMB4 LAMB2	3.20e-04	3	194	2	PS51116
Domain	SAM_DOMAIN	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	4.69e-04	95	194	6	PS50105
Domain	SAM	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	5.25e-04	97	194	6	IPR001660
Domain	P-loop_NTPase	ABCA2 SAMD9 ABCA13 MFHAS1 NAIP GAL3ST2 ABCA7 NOD2 MDN1 LRRIQ1 SUPV3L1 AGAP1 NLRP13 DHX58 DDX60 ATL3 DHX30 MYO15A SEPTIN12 TDRD12	5.45e-04	848	194	20	IPR027417
Domain	MARK/par1	MARK4 MARK2	6.35e-04	4	194	2	IPR033624
Domain	ARM_REPEAT	APC2 ARMC12 KIFAP3 ARMC5	7.70e-04	40	194	4	PS50176
Domain	-	ABCA2 SAMD9 ABCA13 MFHAS1 NAIP ABCA7 NOD2 MDN1 SUPV3L1 AGAP1 NLRP13 DHX58 DDX60 ATL3 DHX30 MYO15A SEPTIN12 TDRD12	8.00e-04	746	194	18	3.40.50.300
Domain	RUN	RUNDC3B SGSM2 SGSM3	8.03e-04	18	194	3	SM00593
Domain	-	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	8.39e-04	106	194	6	1.10.150.50
Domain	RUN	RUNDC3B SGSM2 SGSM3	9.46e-04	19	194	3	PS50826
Domain	RUN	RUNDC3B SGSM2 SGSM3	9.46e-04	19	194	3	PF02759
Domain	Run_dom	RUNDC3B SGSM2 SGSM3	9.46e-04	19	194	3	IPR004012
Domain	KA1	MARK4 MARK2	1.05e-03	5	194	2	PF02149
Domain	KA1_dom	MARK4 MARK2	1.05e-03	5	194	2	IPR001772
Domain	PLPL	PNPLA2 PNPLA3	1.05e-03	5	194	2	IPR033562
Domain	KA1	MARK4 MARK2	1.05e-03	5	194	2	PS50032
Domain	-	MARK4 MARK2	1.05e-03	5	194	2	3.30.310.80
Domain	ANK	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	1.28e-03	251	194	9	SM00248
Domain	ANK_REPEAT	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	1.35e-03	253	194	9	PS50088
Domain	Ankyrin_rpt-contain_dom	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	1.39e-03	254	194	9	IPR020683
Domain	ANK_REP_REGION	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	1.39e-03	254	194	9	PS50297
Domain	SAM/pointed	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	1.40e-03	117	194	6	IPR013761
Domain	Armadillo	APC2 ARMC12 KIFAP3 ARMC5	1.42e-03	47	194	4	IPR000225
Domain	HEAT	ATR NCAPG BRAT1 MROH1	1.54e-03	48	194	4	PF02985
Domain	GAR	DST MACF1	1.57e-03	6	194	2	PS51460
Domain	GAS2	DST MACF1	1.57e-03	6	194	2	PF02187
Domain	-	DST MACF1	1.57e-03	6	194	2	3.30.920.20
Domain	Liprin	PPFIBP2 PPFIA2	1.57e-03	6	194	2	IPR029515
Domain	GAS_dom	DST MACF1	1.57e-03	6	194	2	IPR003108
Domain	GAS2	DST MACF1	1.57e-03	6	194	2	SM00243
Domain	Ankyrin_rpt	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	1.72e-03	262	194	9	IPR002110
Domain	Ank_2	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 IBTK KANK3	1.87e-03	215	194	8	PF12796
Domain	KA1/Ssp2_C	MARK4 MARK2	2.18e-03	7	194	2	IPR028375
Domain	Ank	BARD1 BCOR AGAP1 NFKBIZ TEX14 TNNI3K IBTK KANK3	2.69e-03	228	194	8	PF00023
Domain	HEAT	ATR NCAPG BRAT1 MROH1	3.09e-03	58	194	4	IPR000357
Domain	RasGEF	RASGRP4 RGL2 SH2D3A	3.64e-03	30	194	3	PF00617
Domain	-	RASGRP4 RGL2 SH2D3A	3.64e-03	30	194	3	1.10.840.10
Domain	RASGEF_cat_dom	RASGRP4 RGL2 SH2D3A	3.64e-03	30	194	3	IPR001895
Domain	RasGEF	RASGRP4 RGL2 SH2D3A	3.64e-03	30	194	3	SM00147
Domain	Ras_GEF_dom	RASGRP4 RGL2 SH2D3A	3.64e-03	30	194	3	IPR023578
Domain	PH_dom-spectrin-type	SPTBN5 SPTBN4	3.68e-03	9	194	2	IPR001605
Domain	Patatin	PNPLA2 PNPLA3	3.68e-03	9	194	2	PF01734
Domain	-	DHX58 PDE5A	3.68e-03	9	194	2	3.30.450.40
Domain	PNPLA	PNPLA2 PNPLA3	3.68e-03	9	194	2	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA2 PNPLA3	3.68e-03	9	194	2	IPR002641
Domain	GAF_dom-like	DHX58 PDE5A	3.68e-03	9	194	2	IPR029016
Domain	LRRCT	FLRT2 GP5 VASN	4.38e-03	32	194	3	PF01463
Domain	-	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ TEX14 IBTK KANK3	4.48e-03	248	194	8	1.25.40.20
Domain	SAM_1	CNKSR1 SAMD9 PPFIBP2 PPFIA2	5.48e-03	68	194	4	PF00536
Domain	BBOX	TRIM5 TRIM17 TRIM47 TRIM37	5.77e-03	69	194	4	SM00336
Domain	HEAT_REPEAT	ATR NCAPG BRAT1 MROH1	6.07e-03	70	194	4	PS50077
Domain	-	TRIM5 TRIM17 TRIM47 TRIM37	6.38e-03	71	194	4	4.10.45.10
Domain	zf-B_box	TRIM5 TRIM17 TRIM47 TRIM37	6.70e-03	72	194	4	PF00643
Domain	SH3	SPTA1 OBSCN DST SASH3 SGSM3 MACF1 MYO15A	7.50e-03	216	194	7	PS50002
Domain	MIRO-like	MFHAS1 AGAP1	7.77e-03	13	194	2	IPR013684
Domain	Roc	MFHAS1 AGAP1	7.77e-03	13	194	2	PF08477
Domain	ARM	APC2 KIFAP3 ARMC5	8.22e-03	40	194	3	SM00185
Domain	SH3_domain	SPTA1 OBSCN DST SASH3 SGSM3 MACF1 MYO15A	8.25e-03	220	194	7	IPR001452
Domain	PH	CNKSR1 OBSCN SPTBN5 AGAP1 ARHGEF28 CIT SPTBN4 ARHGEF3	8.72e-03	278	194	8	SM00233
Domain	PH_DOMAIN	CNKSR1 OBSCN SPTBN5 AGAP1 ARHGEF28 CIT SPTBN4 ARHGEF3	8.90e-03	279	194	8	PS50003
Domain	PH_domain	CNKSR1 OBSCN SPTBN5 AGAP1 ARHGEF28 CIT SPTBN4 ARHGEF3	9.08e-03	280	194	8	IPR001849
Domain	ZF_BBOX	TRIM5 TRIM17 TRIM47 TRIM37	9.66e-03	80	194	4	PS50119
Domain	Znf_B-box	TRIM5 TRIM17 TRIM47 TRIM37	1.01e-02	81	194	4	IPR000315
Domain	PH	CNKSR1 OBSCN SPTBN5 AGAP1 CIT SPTBN4 ARHGEF3	1.02e-02	229	194	7	PF00169
Domain	Histone_H2A_CS	H2AZ2 H2AZ1	1.03e-02	15	194	2	IPR032458
Pathway	PID_LKB1_PATHWAY	TSC1 SIK3 MARK4 MARK2 SMAD4	6.69e-05	47	129	5	M87
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTA1 SPTBN5 SPTBN4	8.57e-05	10	129	3	MM15112
Pathway	REACTOME_CILIUM_ASSEMBLY	MKKS IFT172 TRIP11 IFT80 FBF1 DYNLT2 KIFAP3 MARK4 PCNT	9.55e-05	201	129	9	M27472
Pathway	REACTOME_INTRAFLAGELLAR_TRANSPORT	IFT172 TRIP11 IFT80 DYNLT2 KIFAP3	1.09e-04	52	129	5	MM15211
Pathway	REACTOME_INTRAFLAGELLAR_TRANSPORT	IFT172 TRIP11 IFT80 DYNLT2 KIFAP3	1.31e-04	54	129	5	M27482
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 ABCA2 MFHAS1 OBSCN EDC4 FHIP1B CNTROB ABCA7 FANCA NOD2 TAOK2 CDR2L EHBP1L1 DST MDN1 SGSM2 PLEC BRAT1 DOCK6 RGL2 RIC1 LRRC8E PNPLA2 LAMB2 CIT MADD DHX30 KANSL3 MROH1 IL17RE KANK3 MARK4 PAXIP1 PCNT	1.86e-15	1105	202	34	35748872
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 CNKSR1 ABCA2 IFT172 LRSAM1 APC2 TRIP11 BFSP1 DST SUPV3L1 SGSM2 JAKMIP1 SGSM3 PLEC UTRN SMYD3 AGAP1 BICD2 WASHC4 B4GAT1 ADAMTS1 ZBTB47 CIT TRIM5 MADD DHX30 SPTBN4 RTRAF MACF1 ATIC TRIM37 PCNT	3.97e-12	1285	202	32	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 ABCA2 VPS13C BCOR EFR3A TAOK2 DST ZBTB21 SLMAP IFT80 DOCK6 AGAP1 WASHC4 FBF1 SPG11 SIK3 KANSL3 IBTK	2.43e-09	529	202	18	14621295
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 EDC4 NF1 DST MDN1 RPF2 ALDH18A1 PLEC UTRN THOC2 DHX30 RNH1 PELP1 BAZ2A GEMIN4 MACF1 ATIC PCNT	6.07e-08	653	202	18	22586326
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT172 TSC1 FHIP1B SGSM2 TET3 BICD2 MADD DHX30 MROH1 BAZ2A MARK4 MACF1 TRAK2 PCNT	1.35e-07	407	202	14	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MCMBP EDC4 TRIP11 SPICE1 CDR2L NF1 DST MDN1 ZBTB21 PLEC DOCK6 RGL2 UTRN ARHGEF28 CARMIL2 SIK3 MADD MARK4 MACF1 MARK2	1.74e-07	861	202	20	36931259
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	SPTA1 ITPR1 NF1 PLEC PPFIA2 SIK3 MADD MARK4 MARK2	2.17e-07	147	202	9	16959763
Pubmed	Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.	PCSK1 VPS13C SGSM2 MADD	5.27e-07	12	202	4	21873549
Pubmed	Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.	IQCJ-SCHIP1 SCHIP1 SPTBN4	7.69e-07	4	202	3	27979964
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	APC2 TSC1 EDC4 BCOR CCDC177 TRIP11 SPICE1 TAOK2 NF1 DST MDN1 ZBTB21 JAKMIP1 SIK3 CIT ATF6B SPTBN4 PELP1 MACF1 PCNT	1.00e-06	963	202	20	28671696
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	BCOR CDR2L DST MDN1 PLEC DDX60 THOC2 DHX30 PELP1 MACF1	1.26e-06	234	202	10	36243803
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TRIP11 EHBP1L1 DST SLMAP ALDH18A1 PLEC UTRN RNH1 MMRN2 MACF1 ATIC PCNT	1.50e-06	360	202	12	33111431
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MCMBP VPS13C TTC21A OBSCN GAL3ST2 FANCA DST MDN1 ALDH18A1 JAKMIP1 UTRN GP5 LAMB4 PPFIA2 LRRC40 ATIC CXCR2	1.64e-06	736	202	17	29676528
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RUNDC3B VPS13C TSC1 TRIP11 ITPR1 DST DOCK6 RIC1 WASHC4 VEZT SPG11 ATF6B HPS3 MADD	1.72e-06	504	202	14	34432599
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	IQCJ-SCHIP1 SCHIP1 SPTBN4	1.91e-06	5	202	3	18550753
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RUNDC3B CNTROB SPICE1 NF1 DST SLMAP ALDH18A1 DOCK6 UTRN FBF1 THOC2 MARK2 TRIM37	2.41e-06	446	202	13	24255178
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	H2AZ2 EDC4 NF1 DST MDN1 RPF2 ZBTB21 PLEC UTRN LAMB2 LRRC40 THOC2 CIT DHX30 PELP1 RTRAF MACF1 ATIC MARK2 PCNT	2.54e-06	1024	202	20	24711643
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 RASGRP4 PKD1L2 DST WASHC4 CIT RTRAF PAXIP1 MACF1 ATIC MARK2	3.27e-06	322	202	11	26514267
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	CD109 OBSCN SPTBN5 KCNH1 SGSM2 RPF2 PLEC SDK1 PPFIA2	4.94e-06	214	202	9	22199357
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	VPS13C TTC21A NAIP OBSCN BARD1 SGSM2 TTC12 RPF2 DOCK6 UTRN TET3 SMYD3 RIC1 AGAP1 VEZT PPFIBP2 PPFIA2 HPS3 KANSL3 SPTBN4 PARP10 MACF1 TMEM143 PCNT	6.62e-06	1489	202	24	28611215
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SAMD9 ATR ITPR1 FANCA DST SUPV3L1 RIC1 ARHGEF28 ATL3 SIK3 MADD SPAG5 IBTK ARMC5 MARK2	6.93e-06	650	202	15	38777146
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	FANCA SPTBN5 ATRIP RPF2 PLEC DOCK6 LAMB2 PTCD1 FER1L4 RTRAF GEMIN4 H2AZ1 MACF1	7.57e-06	496	202	13	31343991
Pubmed	Functional proteomics mapping of a human signaling pathway.	CNKSR1 DST PPP1R37 PLEC UTRN SDK1 PNPLA2 WASHC4 LAMB2 DHX30 PELP1 PAXIP1 MACF1 SMAD4	1.06e-05	591	202	14	15231748
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ABCA2 TAOK2 DST IFT80 MADD SPTBN4 MACF1	1.16e-05	130	202	7	12421765
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	RASGRP4 MAB21L4 EDC4 EHBP1L1 NF1 MDN1 SUPV3L1 ALDH18A1 IFT80 SMYD3 AGAP1 FBF1 ZC3HC1 SIK3 CIT KIFAP3 TRIM17 ARHGAP18 MYO15A LRMDA CXCR2	1.28e-05	1242	202	21	30973865
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	LRSAM1 TSC1 NCAPG NF1 DST MDN1 SUPV3L1 RPF2 PPP1R37 ALDH18A1 PLEC UTRN WASHC4 ATL3 LRRC40 DHX30 CCNT1 RNH1 BAZ2A GEMIN4 MACF1 ATIC	1.44e-05	1353	202	22	29467282
Pubmed	Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics.	H2AZ2 NOTUM SCNN1G	1.58e-05	9	202	3	36237181
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	H2AZ2 EDC4 DST ALDH18A1 BRAT1 CIT DHX30 RNH1 RTRAF MACF1	1.73e-05	315	202	10	26777405
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP34 OBSCN BCOR ITPR1 KCNH1 PLEC UTRN RCCD1 NFKBIZ THOC2 WDFY4 TRIM5 MADD SPAG5 PTCD1 MACF1 ARHGEF3 TRIM37 PCNT	2.07e-05	1084	202	19	11544199
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	H2AZ2 EDC4 BCOR EFR3A TAOK2 DST MDN1 RPF2 PTRH1 ALDH18A1 SGF29 UTRN AGAP1 LAMB2 CIT DHX30 CCNT1 BAZ2A PTCD1 RTRAF GEMIN4 MACF1 MARK2	2.23e-05	1497	202	23	31527615
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	BARD1 EDC4 CNTROB SPICE1 NCAPG DST SGF29 UTRN ZC3HC1 THOC2 SPAG5 NUDT5 PAXIP1 PCNT	2.77e-05	645	202	14	25281560
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	TRIP11 EFR3A EHBP1L1 DST PPP1R37 PLEC UTRN VASN NUDT5 MACF1 ATIC MARK2 ARHGAP18	2.96e-05	565	202	13	25468996
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	VPS13C IFT80 DOCK6 RIC1 ADAMTS1 KANSL3 IBTK	3.33e-05	153	202	7	10718198
Pubmed	SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.	NF1 SMAD4	3.36e-05	2	202	2	29703253
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	3.36e-05	2	202	2	11002341
Pubmed	Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1.	PCSK1 PCSK1N	3.36e-05	2	202	2	11435430
Pubmed	TRIM47 promotes glioma angiogenesis by suppressing Smad4.	TRIM47 SMAD4	3.36e-05	2	202	2	36203070
Pubmed	TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity.	CNTROB TRIM37	3.36e-05	2	202	2	33983387
Pubmed	Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities.	ATR ATRIP	3.36e-05	2	202	2	14729973
Pubmed	MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway.	MARK4 MARK2	3.36e-05	2	202	2	35192892
Pubmed	Aberrant expression of regulatory cytokine IL-35 and pattern recognition receptor NOD2 in patients with allergic asthma.	IL12A NOD2	3.36e-05	2	202	2	25326182
Pubmed	TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4.	TRIM47 SMAD4	3.36e-05	2	202	2	30979374
Pubmed	Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice.	PNPLA2 LEP	3.36e-05	2	202	2	20842343
Pubmed	Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin.	PNPLA2 PNPLA3	3.36e-05	2	202	2	16380488
Pubmed	H2A.Z facilitates licensing and activation of early replication origins.	H2AZ2 H2AZ1	3.36e-05	2	202	2	31875854
Pubmed	Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage.	ATR ATRIP	3.36e-05	2	202	2	15527801
Pubmed	Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.	PCSK1 PCSK1N	3.36e-05	2	202	2	19528091
Pubmed	Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome.	ATR ATRIP	3.36e-05	2	202	2	23144622
Pubmed	Functional consequences of a novel variant of PCSK1.	PCSK1 PCSK1N	3.36e-05	2	202	2	23383060
Pubmed	Histone H2A.Z is required for androgen receptor-mediated effects on fear memory.	H2AZ2 H2AZ1	3.36e-05	2	202	2	32916283
Pubmed	Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.	LEP PNPLA3	3.36e-05	2	202	2	21068004
Pubmed	Novel alterations in IFT172 and KIFAP3 may induce basal cell carcinoma.	IFT172 KIFAP3	3.36e-05	2	202	2	34674729
Pubmed	Mec1/ATR, the Program Manager of Nucleic Acids Inc.	ATR ATRIP	3.36e-05	2	202	2	28036033
Pubmed	ATR-dependent phosphorylation of ATRIP in response to genotoxic stress.	ATR ATRIP	3.36e-05	2	202	2	15451423
Pubmed	Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.	PCSK1 PCSK1N	3.36e-05	2	202	2	20498726
Pubmed	ATR and ATRIP: partners in checkpoint signaling.	ATR ATRIP	3.36e-05	2	202	2	11721054
Pubmed	SMYD3-Mediated H2A.Z.1 Methylation Promotes Cell Cycle and Cancer Proliferation.	SMYD3 H2AZ1	3.36e-05	2	202	2	27569210
Pubmed	H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.	H2AZ2 H2AZ1	3.36e-05	2	202	2	32266374
Pubmed	Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain.	H2AZ2 H2AZ1	3.36e-05	2	202	2	32868857
Pubmed	Leptin regulates the expression of angiopoietin-like 6.	LEP ANGPTL6	3.36e-05	2	202	2	29852166
Pubmed	The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken.	H2AZ2 H2AZ1	3.36e-05	2	202	2	16204459
Pubmed	ATRIP oligomerization is required for ATR-dependent checkpoint signaling.	ATR ATRIP	3.36e-05	2	202	2	16027118
Pubmed	ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.	ATR ATRIP	3.36e-05	2	202	2	20861269
Pubmed	Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates.	H2AZ2 H2AZ1	3.36e-05	2	202	2	20003410
Pubmed	Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification.	H2AZ2 H2AZ1	3.36e-05	2	202	2	38366138
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TSC1 EDC4 BCOR TRIP11 DST ZBTB21 UTRN THOC2 SPAG5 DHX30 CCNT1 IBTK NUDT5 BAZ2A MACF1 ATIC PCNT	3.60e-05	934	202	17	33916271
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MDN1 JAKMIP1 BRAT1 DOCK6 WASHC4 B4GAT1 ADAMTS1 ATL3 SIK3 CIT IBTK RNH1 COMMD9 MARK2 PCNT	3.88e-05	754	202	15	33060197
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ATR EDC4 NCAPG NF1 MDN1 SUPV3L1 PLEC ZC3HC1 LRRC40 GEMIN4 MACF1 MARK2 PCNT	4.02e-05	582	202	13	20467437
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 MCMBP ESRRA LRSAM1 TSC1 BCOR TRIP11 BICD2 KANSL3 NUDT5 MACF1 TRIM37 PCNT	4.46e-05	588	202	13	38580884
Pubmed	Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.	DST PLEC LAMB2	5.29e-05	13	202	3	9670011
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SPTA1 CCDC168 PKD1L2 CNTROB BFSP1 PNPLA3 SEPTIN12	6.03e-05	168	202	7	30631154
Pubmed	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	BCOR KCNH1 CXCR2	6.70e-05	14	202	3	23470693
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	BCOR SLMAP SCNN1G BICD2 DHX58 ADAMTS1 ATL3 ATF6B PARP10 IBTK	6.88e-05	371	202	10	15747579
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	GATB SUPV3L1 PEX16 RIC1 ADAMTS1 THOC2 CCNT1 PARP10 PAXIP1 SMAD4 PCNT	8.22e-05	457	202	11	32968282
Pubmed	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.	SIK3 MARK4 MARK2	8.34e-05	15	202	3	14976552
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	EDC4 MDN1 ALDH18A1 PLEC NLRC3 RCCD1 THOC2 DHX30 KIFAP3 CCNT1 RNH1 PELP1 BAZ2A RTRAF GEMIN4	8.53e-05	809	202	15	32129710
Pubmed	hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.	ATR ATRIP	1.00e-04	3	202	2	21285353
Pubmed	Association of the PNPLA2, SCD1 and Leptin Expression with Fat Distribution in Liver and Adipose Tissue From Obese Subjects.	PNPLA2 LEP	1.00e-04	3	202	2	30754064
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATR ATRIP	1.00e-04	3	202	2	18344416
Pubmed	A novel protein activity mediates DNA binding of an ATR-ATRIP complex.	ATR ATRIP	1.00e-04	3	202	2	14724280
Pubmed	The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b.	UTRN MARK2	1.00e-04	3	202	2	19945424
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST PLEC	1.00e-04	3	202	2	19932097
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.00e-04	3	202	2	12399109
Pubmed	ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function.	ATR FANCA	1.00e-04	3	202	2	19109555
Pubmed	Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.	ATR ATRIP	1.00e-04	3	202	2	18283122
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	IQCJ-SCHIP1 SCHIP1	1.00e-04	3	202	2	17045569
Pubmed	Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.	H2AZ2 H2AZ1	1.00e-04	3	202	2	34525369
Pubmed	HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.	ATR ATRIP	1.00e-04	3	202	2	17384638
Pubmed	Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers.	H2AZ2 H2AZ1	1.00e-04	3	202	2	32694618
Pubmed	LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL).	PNPLA2 LEP	1.00e-04	3	202	2	27759039
Pubmed	Functional genomic screens identify CINP as a genome maintenance protein.	ATR ATRIP	1.00e-04	3	202	2	19889979
Pubmed	Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant.	H2AZ2 H2AZ1	1.00e-04	3	202	2	20299344
Pubmed	TGF-β signals the formation of a unique NF1/Smad4-dependent transcription repressor-complex in human diploid fibroblasts.	NF1 SMAD4	1.00e-04	3	202	2	21782795
Pubmed	ProSAAS and prohormone convertase 1 are broadly expressed during mouse development.	PCSK1 PCSK1N	1.00e-04	3	202	2	15018810
Pubmed	Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis.	PEX16 PEX26	1.00e-04	3	202	2	15713480
Pubmed	A synthetic NOD2 agonist, muramyl dipeptide (MDP)-Lys (L18) and IFN-β synergistically induce dendritic cell maturation with augmented IL-12 production and suppress melanoma growth.	IL12A NOD2	1.00e-04	3	202	2	21411292
Pubmed	Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis.	SAMD9 RGL2	1.00e-04	3	202	2	21160498
Pubmed	Leptin down-regulates γ-ENaC expression: a novel mechanism involved in low endometrial receptivity.	SCNN1G LEP	1.00e-04	3	202	2	25450293
Pubmed	Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation.	PNPLA2 LEP	1.00e-04	3	202	2	31917686
Pubmed	Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.	TET3 LEP	1.00e-04	3	202	2	31953394
Interaction	TOP3B interactions	USP34 ABCA2 MFHAS1 OBSCN EDC4 FHIP1B CNTROB ABCA7 FANCA NOD2 TAOK2 CDR2L EHBP1L1 DST MDN1 SGSM2 PLEC BRAT1 DOCK6 RGL2 RIC1 LRRC8E PNPLA2 LAMB2 THOC2 CIT MADD DHX30 KANSL3 IBTK MROH1 PELP1 IL17RE KANK3 MARK4 PAXIP1 PCNT	1.01e-07	1470	198	37	int:TOP3B
Interaction	DSCAM interactions	APC2 TRIP11 BFSP1 DST SUPV3L1 SGSM3 PLEC WASHC4 ZBTB47 CIT MACF1 TRIM37	1.30e-07	171	198	12	int:DSCAM
Interaction	USP21 interactions	LRSAM1 NF1 ZBTB21 UTRN AGAP1 DHX58 TRIM5 BAZ2A MARK4 MARK2	4.48e-06	161	198	10	int:USP21
Interaction	KXD1 interactions	IFT172 TRIP11 BFSP1 SPICE1 CDR2L SLMAP IFT80 BICD2 SPAG5 TRAK2	7.26e-06	170	198	10	int:KXD1
Interaction	SYNE3 interactions	VPS13C TSC1 CNTROB SPICE1 TAOK2 DST SLMAP PLEC BICD2 B4GAT1 VEZT FBF1 SPAG5 MACF1 TRIM37 PCNT	8.63e-06	444	198	16	int:SYNE3
Interaction	EEF1AKMT3 interactions	USP34 VPS13C FANCA EHBP1L1 NCAPG MDN1 BRAT1 DOCK6 SMYD3 WASHC4 SPG11 GEMIN4 RINL TRIM47	1.56e-05	364	198	14	int:EEF1AKMT3
Interaction	ACTA1 interactions	SPTA1 LRSAM1 APC2 TSC1 ITPR1 EHBP1L1 DST RPF2 PLEC UTRN TNNI3K MARK4 MACF1 TRIM37	1.93e-05	371	198	14	int:ACTA1
Interaction	GPR17 interactions	ATR FHIP1B FANCA NCAPG MDN1 ATRIP BRAT1 WASHC4 VEZT ATL3 SPG11 GEMIN4	2.48e-05	283	198	12	int:GPR17
Interaction	HCST interactions	ATR FANCA NF1 MDN1 ATRIP BRAT1 LRRC8E ATL3 SPG11 GEMIN4	3.68e-05	205	198	10	int:HCST
Interaction	DCP1A interactions	EDC4 CNTROB ZBTB21 PPP1R37 ALDH18A1 RCCD1 PAXIP1 ARHGAP18 SMAD4	3.99e-05	166	198	9	int:DCP1A
Interaction	GSK3A interactions	H2AZ2 LRSAM1 EDC4 CNTROB SPICE1 DST MDN1 UTRN SPAG5 PARP10 IBTK MACF1 ATIC TRAK2 MARK2	5.78e-05	464	198	15	int:GSK3A
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTBN5 SPTBN4	1.11e-05	7	125	3	1113
GeneFamily	EF-hand domain containing\|Plakins	DST PLEC MACF1	1.76e-05	8	125	3	939
GeneFamily	NLR family	NAIP NOD2 NLRC3 NLRP13	2.46e-05	25	125	4	666
GeneFamily	Sterile alpha motif domain containing	CNKSR1 SAMD9 LRSAM1 SASH3 PPFIBP2 PPFIA2	3.30e-05	88	125	6	760
GeneFamily	ATP binding cassette subfamily A	ABCA2 ABCA13 ABCA7	1.11e-04	14	125	3	805
GeneFamily	Small G protein signaling modulators	SGSM2 SGSM3	1.42e-04	3	125	2	751
GeneFamily	Intraflagellar transport proteins\|Tetratricopeptide repeat domain containing	IFT172 TTC21A IFT80	5.87e-04	24	125	3	615
GeneFamily	Ankyrin repeat domain containing	BARD1 ANKRD63 BCOR AGAP1 NFKBIZ IBTK KANK3	1.48e-03	242	125	7	403
GeneFamily	Patatin like phospholipase domain containing	PNPLA2 PNPLA3	2.06e-03	10	125	2	466
GeneFamily	Laminin subunits	LAMB4 LAMB2	2.99e-03	12	125	2	626
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC2 ARMC12 ARMC5	3.25e-03	43	125	3	409
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM5 TRIM17 TRIM47 TRIM37	4.27e-03	95	125	4	59
GeneFamily	DEAH-box helicases	DHX58 DHX30	5.34e-03	16	125	2	500
GeneFamily	AAA ATPases\|Peroxins	PEX16 PEX26	5.34e-03	16	125	2	957
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 ATR CENPA BARD1 ITPR1 EFR3A DST MDN1 FLRT2 AGAP1 SCHIP1 WASHC4 SPG11 SIK3 THOC2 KIFAP3 IBTK MACF1 TRIM37 SMAD4 PCNT	2.96e-06	856	201	21	M4500
Coexpression	HALLMARK_MITOTIC_SPINDLE	TSC1 CNTROB TAOK2 NF1 DST KIFAP3 MARK4 GEMIN4 ARHGEF3 PCNT	3.42e-06	199	201	10	M5893
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 ATR BCOR TRIP11 EFR3A UTRN LRRC58 THOC2 BAZ2A	2.58e-07	193	202	9	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	10x5'-Lung-Lymphocytic_T_CD8-Tnaive/CM_CD8\|Lung / Manually curated celltypes from each tissue	IL12A SPICE1 GP5 VASN ATF6B TRIM17 FHDC1 TMEM143	8.23e-07	163	202	8	c8e4440d1a857e4da83002303940dd42b273c92e
ToppCell	droplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 CTRC PKD1L2 MDN1 LRRC58 WDFY4 ARHGAP18 MYO15A	8.62e-07	164	202	8	a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell	(01)_Cycling_Basal_(homeostasis)\|World / shred by cell type and Timepoint	H2AZ2 CENPA BARD1 NCAPG CIT SPAG5 H2AZ1 XKR5	1.53e-06	177	202	8	05c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	H2AZ2 CENPA PDGFRL NCAPG CIT SPAG5 H2AZ1 PDE5A	2.40e-06	188	202	8	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	SAMD9 ATRIP UTRN DHX58 DDX60 TRIM5 PARP10 ARHGEF3	3.27e-06	196	202	8	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	Mild-CD4+_T_activated\|World / Disease group and Cell class	SAMD9 TTC21A ATRIP DHX58 DDX60 TRIM5 PARP10 ARHGEF3	3.27e-06	196	202	8	417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	SAMD9 DST ATRIP SASH3 SGF29 TRIM5 COMMD9 ARHGEF3	3.39e-06	197	202	8	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 TAOK2 DST DOCK6 UTRN MACF1 ARHGAP18 PCNT	3.79e-06	200	202	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CD109 TAOK2 DST DOCK6 UTRN MACF1 ARHGEF3 ARHGAP18	3.79e-06	200	202	8	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RUNDC3B TTC21A KCNH1 REC8 THAP9 PDE5A ATIC	4.53e-06	145	202	7	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 ABCA13 APC2 NOD2 VASN MYO15A CXCR2	5.67e-06	150	202	7	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Plasma_cells\|B_lymphocytes / Location, Cell class and cell subclass	MFHAS1 EFR3A TAOK2 CCDC157 RIC1 LRRC40 KIFAP3	6.45e-06	153	202	7	a156710217ef07c07a80ca6504fa0784d86380fa
ToppCell	severe_COVID-19-MAIT\|World / disease group, cell group and cell class (v2)	CNKSR1 ABCA2 OBSCN ALDH18A1 JAKMIP1 AGAP1 FHDC1	6.74e-06	154	202	7	65ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SAMD9 AHRR ARMC12 DDX60 RUBCNL ARHGAP18 MYO15A	7.64e-06	157	202	7	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	FANCA DDX60 FBF1 SH2D3A SPG11 PTCD1 TMEM143	8.30e-06	159	202	7	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TIGD7 SGSM3 DDX60 NUDT5 PTCD1 KANK3 TRIM47	9.38e-06	162	202	7	6ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TIGD7 SGSM3 DDX60 NUDT5 PTCD1 KANK3 TRIM47	9.38e-06	162	202	7	bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCell	facs-Lung-EPCAM-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAB21L4 LRRIQ1 LRRC8E ARHGEF28 CARMIL2 FHDC1 MYO15A	1.28e-05	170	202	7	82ccba6ec53f6ca0d19949a1277434c565af2983
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAB21L4 LRRIQ1 LRRC8E ARHGEF28 CARMIL2 FHDC1 MYO15A	1.28e-05	170	202	7	ab19ea729ed8c8361c870e79893d1a95a1e487fa
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPA BARD1 FANCA NCAPG CIT SPAG5 RINL	1.33e-05	171	202	7	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SAMD9 DST UTRN DDX60 NFKBIZ TRIM5 PARP10	2.07e-05	183	202	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASGRP4 H2AZ2 ABCA13 FANCA NOD2 H2AZ1 CXCR2	2.07e-05	183	202	7	01c7f01498a9894920edf8243e41187cbdf90688
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SPTA1 OBSCN PKD1L2 SDK1 PPFIA2 MYO15A	2.14e-05	184	202	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SPTA1 OBSCN PKD1L2 SDK1 PPFIA2 MYO15A	2.14e-05	184	202	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SPTA1 OBSCN PKD1L2 SDK1 PPFIA2 MYO15A	2.14e-05	184	202	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPICE1 DST ATRIP PNPLA2 DDX60 CCNT1 MARK4	2.22e-05	185	202	7	87151ab95530e70d61328b336518df58db584acb
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C FLRT2 PLEC TET3 NBPF8 LAMB4 PPFIA2	2.29e-05	186	202	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 VPS13C ITPR1 NF1 UTRN SIK3 MACF1	2.46e-05	188	202	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	H2AZ2 CENPA NCAPG CIT SPAG5 H2AZ1 XKR5	2.72e-05	191	202	7	b978afe76754cc56e1672abca27be289bb56375b
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	H2AZ2 CENPA NCAPG CIT SPAG5 H2AZ1 PDE5A	2.72e-05	191	202	7	f764cc21fef87ebad765011098f647ae1bdf6158
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CTRC CNTROB BRAT1 REC8 TEX14 MYO15A	2.73e-05	129	202	6	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	droplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AZ2 CENPA BARD1 NCAPG CIT SPAG5 H2AZ1	2.81e-05	192	202	7	96f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCell	BAL-Mild\|BAL / Compartment, Disease Groups and Clusters	MKKS SAMD9 PDGFRL ATRIP DHX58 DDX60 PARP10	2.81e-05	192	202	7	1a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPA RUNDC3B NCAPG JAKMIP1 ARHGAP18 TDRD12	2.86e-05	130	202	6	0f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CENPA RUNDC3B NCAPG JAKMIP1 ARHGAP18 TDRD12	2.86e-05	130	202	6	fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCell	Mild_COVID-19\|World / Disease group,lineage and cell class （2021.01.30）	SAMD9 ATRIP DHX58 DDX60 TRIM5 PARP10 ARHGEF3	2.90e-05	193	202	7	325b0768827bf8701bfb7f686bb11fd8b1a41a5c
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNKSR1 DST LAMB2 SPG11 KIFAP3 TRAK2 TRIM37	3.00e-05	194	202	7	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNKSR1 DST LAMB2 SPG11 KIFAP3 TRAK2 TRIM37	3.00e-05	194	202	7	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 DST PCSK1N MADD PAXIP1 PDE5A FHDC1	3.10e-05	195	202	7	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Plasma_cells\|normal_Pleural_Fluid / Location, Cell class and cell subclass	MFHAS1 TAOK2 CCDC157 RIC1 LRRC40 KIFAP3	3.11e-05	132	202	6	4e37400ae7375e6986f060234c373194603346f8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 FLRT2 DOCK6 UTRN KANK3 MMRN2 LRMDA	3.20e-05	196	202	7	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	CV-Moderate-1\|Moderate / Virus stimulation, Condition and Cluster	SAMD9 UTRN DHX58 DDX60 TRIM5 PARP10 ARHGEF3	3.20e-05	196	202	7	b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCell	Mild\|World / Disease group and Cell class	SAMD9 ATRIP UTRN DHX58 DDX60 PARP10 ARHGEF3	3.20e-05	196	202	7	5e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 FLRT2 DOCK6 UTRN KANK3 MMRN2 LRMDA	3.20e-05	196	202	7	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CENPA NCAPG CIT SPAG5 KANK3 MMRN2 ARHGAP18	3.31e-05	197	202	7	491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CENPA NCAPG CIT SPAG5 KANK3 MMRN2 ARHGAP18	3.31e-05	197	202	7	8e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	SAMD9 UTRN DHX58 DDX60 TRIM5 PARP10 ARHGEF3	3.42e-05	198	202	7	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	H2AZ2 CENPA BARD1 NCAPG RCCD1 SPAG5 H2AZ1	3.42e-05	198	202	7	48d39018c56ea8ba972c72af8ece10cbeb48fbc8
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	H2AZ2 CENPA NCAPG RCCD1 RUBCNL SPAG5 H2AZ1	3.53e-05	199	202	7	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ABCA2 SAMD9 UTRN AGAP1 ADAMTS1 MACF1 ARHGEF3	3.53e-05	199	202	7	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ABCA2 SAMD9 UTRN AGAP1 ADAMTS1 MACF1 ARHGEF3	3.53e-05	199	202	7	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 NF1 UTRN SMYD3 AGAP1 ARHGEF28 SIK3	3.53e-05	199	202	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CENPA CNTROB NCAPG RCCD1 SPAG5 NUDT5 H2AZ1	3.64e-05	200	202	7	5f2fbd789cc16af411a01c3199583888b260ae91
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	H2AZ2 CENPA BARD1 CNTROB NCAPG SPAG5 H2AZ1	3.64e-05	200	202	7	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CD109 DST PLEC DOCK6 RGL2 ARHGEF3 ARHGAP18	3.64e-05	200	202	7	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SAMD9 VPS13C UTRN DDX60 NFKBIZ MACF1	3.64e-05	200	202	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SAMD9 UTRN ADAMTS1 DDX60 MACF1 ARHGEF3 CXCR2	3.64e-05	200	202	7	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CD109 TAOK2 DST DOCK6 RGL2 ARHGEF3 ARHGAP18	3.64e-05	200	202	7	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CD109 DST PLEC DOCK6 RGL2 ARHGEF3 ARHGAP18	3.64e-05	200	202	7	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	H2AZ2 CENPA BARD1 NCAPG CIT SPAG5 H2AZ1	3.64e-05	200	202	7	2154c976f96489d0fa7bfe6ac1cd21edcbefe735
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CENPA BARD1 FANCA NCAPG CIT SPAG5 PCNT	3.64e-05	200	202	7	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 JAKMIP1 NLRC3 REC8 CARMIL2 RINL	4.50e-05	141	202	6	d3ce2218bfa9750795d920e1ef162ea44efb2e66
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC21A SPTBN5 MYO15A TDRD12	4.65e-05	44	202	4	405ac4aeee539322cfe661c7531248f81271be8d
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC21A SPTBN5 MYO15A TDRD12	4.65e-05	44	202	4	a2c99e8ca635590a1f167b68bc390e2aa01e26be
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPA RUNDC3B ABCA13 NCAPG CIT MMRN2	5.47e-05	146	202	6	c0e1836845c083bf9d88a620da27acbfdea9fb20
ToppCell	Int-URO-Lymphocyte-T_NK-CD8_Naive\|Int-URO / Disease, Lineage and Cell Type	IFT172 OBSCN EDC4 ALDH18A1 FHDC1 TRIM47	6.84e-05	152	202	6	52d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CNKSR1 MAB21L4 ATRIP SCNN1G FBF1 SPTBN4	7.09e-05	153	202	6	a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 BARD1 KCNH1 NLRC3 PPFIA2 TEX14	8.77e-05	159	202	6	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 BARD1 KCNH1 NLRC3 PPFIA2 TEX14	8.77e-05	159	202	6	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PKD1L2 SASH3 JAKMIP1 TRIM5 BTBD16 RINL	9.08e-05	160	202	6	4a0ae0a83a10dbfc13591f4d2228ba8bcd2c2275
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRSAM1 NCAPG MDN1 RPF2 KANSL3 ATIC	9.40e-05	161	202	6	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TAOK2 NCAPG RGL2 SPAG5 ARHGAP18 XKR5	1.01e-04	163	202	6	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MAB21L4 SPTBN5 ATRIP SCNN1G FBF1 SPTBN4	1.01e-04	163	202	6	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	BAL-Severe-cDC_8\|Severe / Compartment, Disease Groups and Clusters	CD109 GAL3ST2 CDR2L AHRR SH2D3A THAP9	1.04e-04	164	202	6	e8cbe7e01eca32886eb44e02d5333056b6bebc50
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1N AGBL1 CARMIL2 SPAG5 TNNI3K	1.06e-04	103	202	5	3f4e4600c8a9af3534479ca19905c3d31c4c55bb
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 BARD1 KCNH1 NLRC3 PPFIA2 TEX14	1.11e-04	166	202	6	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 BARD1 KCNH1 NLRC3 PPFIA2 TEX14	1.11e-04	166	202	6	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	H2AZ2 CENPA NCAPG SPAG5 TRIM17 H2AZ1	1.23e-04	169	202	6	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BARD1 FANCA NCAPG CIT SPAG5 XKR5	1.23e-04	169	202	6	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH18A1 REC8 RCCD1 WDFY4 SPTBN4 ARHGAP18	1.23e-04	169	202	6	46f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 TRIP11 SPICE1 NOD2 PTRH1 KANSL3	1.23e-04	169	202	6	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPF2 ALDH18A1 REC8 RCCD1 WDFY4 ARHGAP18	1.23e-04	169	202	6	9c9bb1b32fc6e22359424a262178906c3954415d
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	CENPA NCAPG CIT SPAG5 TRIM17 PAXIP1	1.27e-04	170	202	6	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SAMD9 UTRN TET3 ARHGEF28 DDX60 NUDT5	1.27e-04	170	202	6	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	H2AZ2 CENPA BARD1 NCAPG PPFIA2 SPAG5	1.31e-04	171	202	6	05014cf6746e6663e376fdd681f1b43a7081c603
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	H2AZ2 CENPA BARD1 NCAPG PPFIA2 SPAG5	1.31e-04	171	202	6	d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNKSR1 MAB21L4 SCNN1G AGBL1 MROH1	1.33e-04	108	202	5	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD109 BARD1 NCAPG CIT SPAG5 XKR5	1.35e-04	172	202	6	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ADAMTS1 NFKBIZ LRRC58 HPS3 MACF1	1.39e-04	173	202	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ADAMTS1 NFKBIZ LRRC58 HPS3 MACF1	1.39e-04	173	202	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ADAMTS1 NFKBIZ LRRC58 HPS3 MACF1	1.39e-04	173	202	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA2 FANCA WDFY4 PEX26 ATIC ARHGAP18	1.44e-04	174	202	6	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SAMD9 SASH3 UTRN REC8 DHX58 DDX60	1.48e-04	175	202	6	97616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ADAMTS1 NFKBIZ LRRC58 HPS3 MACF1	1.48e-04	175	202	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAKMIP1 UTRN NLRC3 PTCD1 ARHGEF3 CXCR2	1.53e-04	176	202	6	6b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCell	droplet-Bladder-nan-24m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 RUNDC3B NCAPG SASH3 CARMIL2 RINL	1.53e-04	176	202	6	0089b50d607f4d2f18639fab0f3fc779227baa7a
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BARD1 C8orf48 DST SGSM3 DHX58 MMRN2	1.58e-04	177	202	6	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BARD1 C8orf48 DST SGSM3 DHX58 MMRN2	1.58e-04	177	202	6	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPA PDGFRL NCAPG FLRT2 FER1L4 H2AZ1	1.58e-04	177	202	6	4197cf2b1e743230c821f422836fa5991b155a52
Drug	plakin	SPTA1 SPTBN5 DST PLEC UTRN SPTBN4 PARP10 MACF1	6.54e-07	82	201	8	CID000018752
Disease	obesity (implicated_via_orthology)	PCSK1 MKKS TSC1 ITPR1 PCSK1N SDK1 PNPLA2 LEP ANGPTL6 PNPLA3	1.52e-06	215	191	10	DOID:9970 (implicated_via_orthology)
Disease	C-reactive protein measurement	PCSK1 USP34 CENPA MFHAS1 NUP210L VPS13C IFT172 CCDC168 ITPR1 FANCA PPP1R37 ARHGEF28 SPG11 THOC2 CIT MADD PTCD1 MARK4 MACF1 LRMDA	1.17e-04	1206	191	20	EFO_0004458
Disease	Seckel syndrome 1	ATR PCNT	1.25e-04	3	191	2	C4551474
Disease	Chronic myeloproliferative disorder	ATR ATRIP PCNT	2.40e-04	19	191	3	C1292778
Disease	nuclear protein MDM1 measurement	TRIM5 ARHGEF3	2.48e-04	4	191	2	EFO_0802822
Disease	Monogenic Non-Syndromic Obesity, Autosomal Recessive	PCSK1 LEP	2.48e-04	4	191	2	cv:CN043636
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK4 MARK2	2.48e-04	4	191	2	DOID:0070356 (implicated_via_orthology)
Disease	Seckel syndrome	ATR ATRIP PCNT	3.76e-04	22	191	3	C0265202
Disease	ovarian cancer (is_implicated_in)	BARD1 FANCA NOD2 SMAD4	4.80e-04	56	191	4	DOID:2394 (is_implicated_in)
Disease	Chanarin-Dorfman syndrome (implicated_via_orthology)	PNPLA2 PNPLA3	6.15e-04	6	191	2	DOID:0050729 (implicated_via_orthology)
Disease	Colorectal Carcinoma	PDGFRL ABCA13 APC2 CD109 OBSCN NCAPG NF1 SCNN1G JAKMIP1 HPS3 TNNI3K MMRN2 SMAD4	6.98e-04	702	191	13	C0009402
Disease	Seckel syndrome (implicated_via_orthology)	ATR ATRIP	8.57e-04	7	191	2	DOID:0050569 (implicated_via_orthology)
Disease	Urogenital Abnormalities	SAMD9 APC2	8.57e-04	7	191	2	C0042063
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	8.57e-04	7	191	2	DOID:4644 (is_implicated_in)
Disease	able to hear with hearing aids	AHRR ARHGEF28	8.57e-04	7	191	2	EFO_0009720
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	SPG11 SIK3 MACF1 PNPLA3	9.48e-04	67	191	4	EFO_0008595, EFO_0020946
Disease	peroxisomal biogenesis disorder (is_implicated_in)	PEX16 PEX26	1.14e-03	8	191	2	DOID:0080377 (is_implicated_in)
Disease	autoimmune disease (is_implicated_in)	CENPA NOD2	1.14e-03	8	191	2	DOID:417 (is_implicated_in)
Disease	Alzheimer disease, educational attainment	SAMD9 ABCA7 KCNH1 PPP1R37 AGAP1 LAMB2 MARK4	1.18e-03	247	191	7	EFO_0011015, MONDO_0004975
Disease	Adult Hepatocellular Carcinoma	PDGFRL TSC1	1.46e-03	9	191	2	C0279607
Disease	age at menarche, spine bone mineral density	RUNDC3B KCNH1	1.81e-03	10	191	2	EFO_0004703, EFO_0007701
Disease	Kunitz-type protease inhibitor 2 measurement	RASGRP4 ARHGEF3	1.81e-03	10	191	2	EFO_0008200
Disease	Cognition Disorders	TSC1 LAMB2 SMAD4	1.91e-03	38	191	3	C0009241
Disease	Jeune thoracic dystrophy	IFT172 IFT80	2.21e-03	11	191	2	C0265275
Disease	thyrotoxic periodic paralysis	FHDC1 LRMDA	2.21e-03	11	191	2	MONDO_0019201
Disease	PEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER)	PEX16 PEX26	2.21e-03	11	191	2	C4721541
Disease	sphingomyelin measurement	PDGFRL DOCK6 SDK1 SIK3 MADD PELP1 KANK3	2.31e-03	278	191	7	EFO_0010118
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	EHBP1L1 SPG11 SIK3 MADD MACF1	2.51e-03	144	191	5	EFO_0004611, EFO_0020943
Disease	hemorrhoid	NF1 PLEC BICD2 MYO15A XKR5	2.74e-03	147	191	5	EFO_0009552
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	MFHAS1 DOCK6 SPG11 SIK3 TRIM5 MACF1 PNPLA3	2.98e-03	291	191	7	EFO_0008317, EFO_0020946
Disease	obsolete_red blood cell distribution width	SAMD9 H2AZ2 ATR SPTA1 ABCA7 AHRR EHBP1L1 DOCK6 AGAP1 CARMIL2 RCCD1 ZC3HC1 SIK3 CIT TRIM5 PARP10 MARK4 PNPLA3	2.99e-03	1347	191	18	EFO_0005192
Disease	Zellweger Spectrum	PEX16 PEX26	3.10e-03	13	191	2	C3658299
Disease	Zellweger-Like Syndrome	PEX16 PEX26	3.10e-03	13	191	2	C0751594
Disease	Infantile Refsum Disease (disorder)	PEX16 PEX26	3.10e-03	13	191	2	C0282527
Disease	Malignant neoplasm of salivary gland	FANCA PCSK1N MARK2	3.10e-03	45	191	3	C0220636
Disease	Osteosarcoma	ESRRA BCOR KCNH1	3.51e-03	47	191	3	C0029463
Disease	Salivary Gland Neoplasms	FANCA PCSK1N MARK2	3.51e-03	47	191	3	C0036095
Disease	Adenocarcinoma of large intestine	PDGFRL TNNI3K MARK4 SMAD4	3.56e-03	96	191	4	C1319315
Disease	phospholipids:total lipids ratio	DOCK6 SIK3 TRIM5 MADD MACF1 PNPLA3	3.72e-03	227	191	6	EFO_0020946
Disease	Adenoid Cystic Carcinoma	BCOR FANCA PCSK1N MARK2	4.11e-03	100	191	4	C0010606
Disease	apolipoprotein B measurement	CENPA NCAPG NF1 PPP1R37 PLEC DOCK6 SIK3 TRIM5 PARP10 FER1L4 MARK4	4.12e-03	663	191	11	EFO_0004615
Disease	Peroxisome biogenesis disorders	PEX16 PEX26	4.14e-03	15	191	2	C1832200
Disease	Adrenoleukodystrophy, Neonatal	PEX16 PEX26	4.14e-03	15	191	2	C0282525
Disease	Alzheimer disease	ABCA7 CDR2L PPP1R37 PLEC SDK1 ADAMTS1 MROH1 MARK4 MYO15A	4.52e-03	485	191	9	MONDO_0004975
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SPG11 SIK3 MACF1 PNPLA3	4.57e-03	103	191	4	EFO_0008595, EFO_0020944
Disease	infantile hypertrophic pyloric stenosis	SLMAP SIK3	4.71e-03	16	191	2	EFO_0004707
Disease	level of triacylglycerol (56:6) in blood serum	SIK3 PNPLA3	4.71e-03	16	191	2	OBA_2020007
Disease	Zellweger Syndrome	PEX16 PEX26	4.71e-03	16	191	2	C0043459
Disease	2-hydroxyglutarate measurement	GAL3ST2 PCNT	4.71e-03	16	191	2	EFO_0021506
Disease	Huntington's disease (biomarker_via_orthology)	ITPR1 LEP	4.71e-03	16	191	2	DOID:12858 (biomarker_via_orthology)
Disease	IGFBP-3 measurement	MFHAS1 ATRIP FHDC1	5.20e-03	54	191	3	EFO_0004626
Disease	Oral ulcer	NOD2 IQCJ-SCHIP1 IFT80 SCHIP1	5.23e-03	107	191	4	HP_0000155
Disease	gestational diabetes (is_marker_for)	LEP ANGPTL6	5.32e-03	17	191	2	DOID:11714 (is_marker_for)
Disease	Moyamoya Disease	NF1 PCNT	5.32e-03	17	191	2	C0026654
Disease	Ciliopathies	MKKS TSC1 SCNN1G IFT80	5.76e-03	110	191	4	C4277690
Disease	aspartate aminotransferase measurement	PCSK1 MCMBP MFHAS1 OBSCN ITPR1 NF1 IFT80 AGAP1 TRIM5 MADD BAZ2A PNPLA3 MYO15A	6.21e-03	904	191	13	EFO_0004736
Disease	urate measurement, spine bone mineral density	KCNH1 RIC1 MARK4	6.34e-03	58	191	3	EFO_0004531, EFO_0007701

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLDRATDLILDHIRE	PTRH1	191	Q86Y79
LIELLDSDRQEHQDL	NAIP	756	Q13075
RDRLNAELDHLASLL	AHRR	41	A9YTQ3
AEARQSLFLELLHIL	BRAT1	586	Q6PJG6
QLDLTARDLELTNHR	CDR2L	86	Q86X02
ARDLELTNHRLVLES	CDR2L	91	Q86X02
ADEDLRTAILLLAHG	AGAP1	741	Q9UPQ3
DSLIPLHEELLSQLR	ARHGEF3	171	Q9NR81
LRNLLHDNELSDLKE	BARD1	111	Q99728
ALTQRLELLELDHEQ	BICD2	791	Q8TD16
LEDLLGVLASAHILQ	BTBD16	176	Q32M84
ASVDNLLHLSGLLER	B4GAT1	101	O43505
VQDLLVRLLKAALHD	BAZ2A	896	Q9UIF9
ALLDGLALNTHLRDL	CARMIL2	481	Q6F5E8
HLQLAIRGDEELDSL	H2AZ2	86	Q71UI9
LLDNLTVREHLLLFA	ABCA13	3926	Q86UQ4
DAALTLALVRALLEL	ARMC5	251	Q96C12
LLEHSFTLLNEVGLL	GATB	391	O75879
LDAHENLLLAEGTLR	AP5S1	126	Q9NUS5
LELLDELTHEFLQIL	CCNT1	231	O60563
VHERDVNTDFLLILL	DHX30	561	Q7L2E3
DLDLVTDLVLHIDAR	DHX30	651	Q7L2E3
EEHGQLLALLAELLR	DHX30	1166	Q7L2E3
RSLAEITELIHIALL	PDSS2	146	Q86YH6
DAVENDHLEIVRLLL	BCOR	1536	Q6W2J9
LSHAVLLELVIDRLL	CCDC157	71	Q569K6
LLELETRLREVSLEH	CIT	851	O14578
RAALAQLLKLEELHL	FLRT2	126	O43155
ANLLHDRLAQILELT	EFR3A	771	Q14156
EESRLADRLLALVIH	ARMC12	286	Q5T9G4
HSLLEAAEDLAQELL	ABCA7	181	Q8IZY2
LSAEEDALDQHLQRL	AGBL1	1061	Q96MI9
HLARFVLDALDRSII	ANKRD63	26	C9JTQ0
RQLELGAEHALLLDA	RCCD1	161	A6NED2
LEEASLRLLAKEHAQ	RAX2	161	Q96IS3
LLSLEAVHRAVALEL	REC8	476	O95072
LTDELHLFSLEDLVR	RUBCNL	556	Q9H714
VLEDLLVATSDGLLH	RIC1	151	Q4ADV7
LRLHAFDQQLDLELR	ADAMTS1	76	Q9UHI8
LAELRHSQEELLQRL	EDC4	961	Q6P2E9
ALDEELVLALTHLEL	ARHGEF28	131	Q8N1W1
LLESFLLQERIDEHL	C8orf48	221	Q96LL4
LSEIILISCENDLHL	PAXIP1	1021	Q6ZW49
ARLSLENTEAELHLL	FHDC1	366	Q9C0D6
LLEFALHEDLLTRVL	FHIP1B	96	Q8N612
AASLREEQLHLSLLV	MAB21L4	176	Q08AI8
ILEHLPARLNEALLE	PNPLA2	296	Q96AD5
LLNLGRQLISDHVDL	MKKS	276	Q9NPJ1
NSDELIHFRLRLLEE	MDN1	211	Q9NU22
KNRITDLENLLDHLA	LRMDA	56	Q9H2I8
ALHLAAEEANLELIR	NFKBIZ	616	Q9BYH8
DEDRLLATLLHNLIS	MADD	1366	Q8WXG6
LLVEGLTDLQLREHD	NLRC3	91	Q7RTR2
ALAHLEELDVSFNRL	MFHAS1	156	Q9Y4C4
DRVFHESILLAIALL	ITPR1	1826	Q14643
ERQLVALLEELSAEH	LRSAM1	571	Q6UWE0
DLLFRQILHDTLSEA	MYO15A	2711	Q9UKN7
LALIQIEEHAIQDLL	IBTK	1306	Q9P2D0
FAALLEDALRHEAVL	MMRN2	596	Q9H8L6
EDLRDGHNLISLLEV	DST	61	Q03001
EFHDTRLRLQDLLLE	FER1L4	76	A9Z1Z3
LLLHAADSEAQRRLV	IL17RE	491	Q8NFR9
NLNLIHLSDLNDELL	DDX60	366	Q8IY21
AVQELARALAHLLEA	PCSK1N	71	Q9UHG2
NDLLQRLDALVAEEH	NUDT5	176	Q9UKK9
AADLLVVHLDFRAAL	PEX26	41	Q7Z412
LEILALLIAALSHDL	PDE5A	641	O76074
ALAVRLEGDELLDHL	PNPLA3	291	Q9NST1
LEGDELLDHLRLSIL	PNPLA3	296	Q9NST1
HIDRALDATEILGIL	CXCR2	291	P25025
ANEDLLHLLTLSLDL	RASGRP4	401	Q8TDF6
QHREQLLLEELVSLV	EHBP1L1	1461	Q8N3D4
HSRLAEVLQLGSDIL	KCNH1	181	O95259
LSLHLLVEELRLNPD	MACF1	761	O94854
LENLRDLLHVLAFSK	LEP	101	P41159
ALNLTLRQLDQHLDL	LAMB2	1306	P55268
QHVIDDLSLERERLL	JAKMIP1	406	Q96N16
ALQELDLKDNHLRSI	LRRC8E	606	Q6NSJ5
ATLVLLDHLSLARNL	IL12A	11	P29459
TLHALEDLLTSLLQR	MROH1	896	Q8NDA8
SIHLEALDLLSALIL	PELP1	371	Q8IZL8
AHSAELEAVLLALAR	PCNT	1886	O95613
ILNLIHLEELSLRGN	LRRC58	231	Q96CX6
LHLIEDLRLALEMLE	PPFIBP2	51	Q8ND30
LENLVLLRELHLDDN	LRRIQ1	1031	Q96JM4
LRDGHNLISLLEVLS	MACF1	106	Q9UPN3
HLADLLTDQRDEILL	ALDH18A1	391	P54886
ACNALETLLIHRDLL	ALDH18A1	611	P54886
HLELGQDLLITISLA	PKD1L2	461	Q7Z442
LSKLALEARQLHIAE	IFT172	631	Q9UG01
LALKVNHSLLRLDLD	PPP1R37	411	O75864
VLARLHEEAQLLAEL	OBSCN	716	Q5VST9
SAQQLNEDLRLHLLL	NOTUM	81	Q6P988
EAEELLQALHRLTRL	COMMD9	56	Q9P000
FRLVLIAEHLDESLV	GAL3ST2	221	Q9H3Q3
LEAELDARHLAQALE	APC2	726	O95996
ILEHESLGLLRDATA	ATR	1706	Q13535
LIDTHNRLLLQTAEL	CD109	1221	Q6YHK3
AELLHSQARLAELEA	FBF1	581	Q8TES7
VSLILQAERHFLLVD	IFT80	376	Q9P2H3
LLLRNDIALIKLAEH	CTRC	116	Q99895
RILASKLLHEELALQ	DOCK6	901	Q96HP0
LLALQEAAEAFLVHL	CENPA	91	P49450
IQLLLLGDLLEQLDH	FNDC11	121	Q9BVV2
LRSHQDLNALLLEVE	FANCA	51	O15360
KEADEALLHNLRLQL	BFSP1	146	Q12934
LLIHDTVRAVDALAA	DHX58	291	Q96C10
LGSELEALRQHLEAL	ABCA2	116	Q9BZC7
ELRLHPEALNLSLDE	ABCA2	521	Q9BZC7
QLTSRGDHELLVLLE	ANGPTL6	336	Q8NI99
LASILLQDHIRDLDV	ATL3	46	Q6DD88
IVHRDLKAENLLLDA	MARK2	171	Q7KZI7
NIVHRDLKAENLLLD	MARK4	176	Q96L34
LERLLLHSNRLVSLD	GP5	196	P40197
AERELELLRASLEHQ	KANK3	351	Q6NY19
LLFQLSVHERELDLV	KANSL3	21	Q9P2N6
HLQLAIRGDEELDSL	H2AZ1	86	P0C0S5
LDHVSIRLDLEALFR	LAMB4	111	A4D0S4
LARHQEELLLLEQRA	CCDC177	346	Q9NQR7
AVELLSLLADHDQLA	ATRIP	606	Q8WXE1
LAHLFLSRDQVRLLE	CCDC168	236	Q8NDH2
LLALQLHLLRALAQD	SDK1	86	Q7Z5N4
QHRAKLLTAAELLLD	SASH3	301	O75995
RHLLADLEQETREAL	SCNN1G	111	P51170
EAVEQLREALHEALL	ESRRA	346	P11474
EEILHDSLDRLLAKL	CCDC153	156	Q494R4
QLSEHRELETLRAAL	CNTROB	341	Q8N137
EHEDLLNITLRLLLN	KIFAP3	356	Q92845
LRLLPALTVLDIHDN	LRRC40	101	Q9H9A6
ELKAERNNTRLLLEH	PPFIA2	126	O75334
DDLHQLLVVARCLSL	MCMBP	591	Q9BTE3
AHLRVSDIQELELDL	NUP210L	976	Q5VU65
EHLLLLLLLTDVNSK	OR10G6	6	Q8NH81
EEEAALQLALHRSLE	PARP10	651	Q53GL7
VLEHLLLNDNLLAEL	NYX	231	Q9GZU5
EARILFLLQLLADHV	PEX16	296	Q9Y5Y5
ILLQRIEDSDLAHKL	RUNDC3B	306	Q96NL0
VLNEAAQILRLLHIE	RTRAF	196	Q9Y224
KDLHLLEEIALTLRA	UTRN	1006	P46939
VFLADHLAEQLTLLD	RGL2	241	O15211
HLAEQLTLLDAELFL	RGL2	246	O15211
ELLESLLQEVEHQLR	TRIM37	216	O94972
SFLQELLALRLALED	TRIM47	331	Q96LD4
LTALSRHDLEDNLLS	SPAG5	426	Q96R06
RHDLEDNLLSSLVIL	SPAG5	431	Q96R06
LRLADLLIAEQEHSS	TEX14	286	Q8IWB6
SLLDFERSLIIHIDN	HPS3	171	Q969F9
RSLNEHLQALLTLDE	NBPF8	86	Q3BBV2
VQLLLIRDELHTEQD	SCHIP1	446	P0DPB3
VDDLIALLDLAEHAS	SAMD9	1146	Q5K651
QSLLFLRLCHLILDE	TDRD12	561	Q587J7
EIHLHRALQLLDEVL	SMAD4	526	Q13485
LLDTVALNLHRIDKD	SGSM2	786	O43147
RLDKLLQEHDIELSL	SGSM3	261	Q96HU1
HRDLKAENLLLDANL	SIK3	186	Q9Y2K2
ELLQEHSRAANLIVL	SLC12A1	1041	Q13621
LLARHSLDQDLLRED	TAOK2	651	Q9UL54
ISVLDHALESLDNLR	SUPV3L1	351	Q8IYB8
LVQLLLIRDELHTEQ	IQCJ-SCHIP1	521	B3KU38
AVEGRLSSLLELHLQ	OR6B3	311	Q8NGW1
LLGLLLVHEALEDVT	PDGFRL	6	Q15198
REHSLIEDLILLLEE	SMYD3	406	Q9H7B4
LDLVLRRTHLASDDL	RPF2	221	Q9H7B2
AEVVELLQRHDLLEA	SPTBN5	566	Q9NRC6
ELLLHRHQDLEKLLA	SPTBN5	3456	Q9NRC6
DHRELIDALTAEILR	SPICE1	406	Q8N0Z3
ILDSQLRLHLLDNAD	ANHX	46	E9PGG2
ELLLRDLDQLFLSSD	ATF6B	486	Q99941
SHLAKDLLVLLNEIL	NCAPG	861	Q9BPX3
IRDLLEELSQVLHED	CNKSR1	146	Q969H4
IHALLQSAELLEEEA	SPG11	1931	Q96JI7
LLLHLLEDELDHRTD	ZC3HC1	216	Q86WB0
ELLQDVRHLLTDLQD	RINL	301	Q6ZS11
QSLRELISDLEHRLQ	TRIM5	226	Q9C035
THLLAERDRDLELAA	TRAK2	116	O60296
LLLFLHESLILLSEN	UHRF1BP1L	826	A0JNW5
AHAISLLSALNEERL	ZBTB21	11	Q9ULJ3
DEIRTLRDQLLLLHN	TSC1	686	Q92574
SQRLKDALLDHDLAL	THOC2	726	Q8NI27
ADRLIRLLQETSALH	NOD2	466	Q9HC29
SELLSALALRAQDEH	TMEM143	351	Q96AN5
HDAEDILLLLLGLIV	SPEM2	21	Q0P670
LSEALLDLSDHRRNL	THAP9	701	Q9H5L6
ADSRIAELLTELHQL	SGF29	6	Q96ES7
LELLERHQTLALAGA	SH2D3A	361	Q9BRG2
ELLSARDEILLLHQA	SLMAP	576	Q14BN4
LRDLLIRSHLQDLKD	SEPTIN12	286	Q8IYM1
ADNLELSLFSHLLEI	WDFY4	1476	Q6ZS81
ALLEQNLHTLDSLRI	NF1	2336	P21359
AATLLANHSLRELDL	RNH1	391	P13489
SLEEADALLARHAAL	SPTBN4	1121	Q9H254
ASLDLVLHLEALLSF	VPS13C	1536	Q709C8
DLLHLQLICRDTEDE	SPTA1	791	P02549
DLRDGHNLISLLEVL	PLEC	206	Q15149
DELGIILAHTNLRLF	ATIC	576	P31939
EDLDTLQTALALARH	TET3	251	O43151
LLELVEALRLNGELH	TTC21A	626	Q8NDW8
RFLLESELLLHRQTD	ZBTB47	471	Q9UFB7
QHDAASLLKLFIREL	ARHGAP18	396	Q8N392
LLLLDLSHNSLLALE	VASN	171	Q6EMK4
DRQGHSLELLLLQLE	TRIM17	226	Q9Y577
RDISLDSELHDLRLN	TRIP11	461	Q15643
LLTVLLTLDEIIDNH	WASHC4	196	Q2M389
LIINHLDLTRLLEAL	TTC12	376	Q9H892
SQTTLLDLDALARHL	USP34	1751	Q70CQ2
RLDSLHTILQQEVLL	VEZT	91	Q9HBM0
EADLSALRLLEALLQ	XKR5	106	Q6UX68
LLLALLDEHQVEADL	PTCD1	506	O75127
VLRFHDEDVRALLLL	TIGD7	281	Q6NT04
SLFSLLHEQKRILDL	TNNI3K	546	Q59H18
LLISRLDLHICDDSQ	UHRF1BP1	326	Q6BDS2
VFSHLSLELADRILL	DYNLT2	121	Q8IZS6
LSLDRKDLAIHILEL	GEMIN4	721	P57678
LLNKNIARELEDTLH	NLRP13	591	Q86W25
HRDDRLLQALVDILN	PCSK1	736	P29120