Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2A3

6.23e-0735394GO:0015020
GeneOntologyMolecularFunction3-mercaptopyruvate sulfurtransferase activity

MPST TST

3.72e-062392GO:0016784
GeneOntologyMolecularFunctioncholesterol O-acyltransferase activity

SOAT2 SOAT1

1.11e-053392GO:0034736
GeneOntologyMolecularFunctionsterol O-acyltransferase activity

SOAT2 SOAT1

1.11e-053392GO:0004772
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

XYLT1 UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.15e-05153395GO:0008194
GeneOntologyMolecularFunctionretinoic acid binding

UGT2B4 UGT2B15 UGT2B17

2.18e-0528393GO:0001972
GeneOntologyMolecularFunctionthiosulfate sulfurtransferase activity

MPST TST

3.70e-055392GO:0004792
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKX PRKY

7.76e-057392GO:0004691
GeneOntologyMolecularFunctionretinoid binding

UGT2B4 UGT2B15 UGT2B17

1.12e-0448393GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT2B4 UGT2B15 UGT2B17

1.19e-0449393GO:0019840
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKX PRKY

1.33e-049392GO:0004690
GeneOntologyMolecularFunctionO-acyltransferase activity

MOGAT1 SOAT2 SOAT1

2.08e-0459393GO:0008374
GeneOntologyMolecularFunctionglycosyltransferase activity

XYLT1 UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.32e-04288395GO:0016757
GeneOntologyMolecularFunctionsulfurtransferase activity

MPST TST

2.42e-0412392GO:0016783
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2A3

7.46e-04211394GO:0016758
GeneOntologyMolecularFunctionfatty-acyl-CoA binding

SOAT2 SOAT1

8.38e-0422392GO:0000062
GeneOntologyMolecularFunctionfatty acid derivative binding

SOAT2 SOAT1

9.98e-0424392GO:1901567
GeneOntologyMolecularFunctionacyl-CoA binding

SOAT2 SOAT1

1.17e-0326392GO:0120227
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT2B4 UGT2B15 UGT2B17

1.19e-03107393GO:0033293
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TRPM6 ROCK1 PRKX PRKY GRK5

1.67e-03446395GO:0004674
GeneOntologyMolecularFunctionprotein serine kinase activity

TRPM6 ROCK1 PRKX PRKY

5.35e-03363394GO:0106310
GeneOntologyMolecularFunctioncholesterol binding

SOAT2 SOAT1

5.73e-0358392GO:0015485
GeneOntologyMolecularFunctionprotein kinase activity

TRPM6 ROCK1 PRKX PRKY GRK5

5.96e-03600395GO:0004672
GeneOntologyMolecularFunctionsterol binding

SOAT2 SOAT1

8.48e-0371392GO:0032934
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B4 UGT2B15 UGT2B17 UGT2A3

6.38e-0821394GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.58e-0726394GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.58e-0726394GO:0006063
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B15 UGT2B17

3.48e-078393GO:0070980
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT2B4 UGT2B15 UGT2B17 GSTO1

6.89e-0737394GO:0042178
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B15 UGT2B17

7.43e-0710393GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B4 UGT2B15 UGT2B17

1.36e-0612393GO:0052697
GeneOntologyBiologicalProcessestrogen metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.77e-0652394GO:0008210
GeneOntologyBiologicalProcesscyanate catabolic process

MPST TST

3.48e-062392GO:0009440
GeneOntologyBiologicalProcesscyanate metabolic process

MPST TST

3.48e-062392GO:0009439
GeneOntologyBiologicalProcesssteroid metabolic process

UGT2B4 LRP2 UGT2B15 UGT2B17 SOAT2 UGT2A3 SOAT1

5.89e-06376397GO:0008202
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT2B4 UGT2B15 UGT2B17

4.64e-0537393GO:0042537
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B4 UGT2B15 UGT2B17

5.04e-0538393GO:0008209
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT2B4 UGT2B15 UGT2B17 GSTO1

1.43e-04141394GO:0006805
GeneOntologyBiologicalProcesssulfur amino acid catabolic process

MPST TST

1.90e-0411392GO:0000098
GeneOntologyBiologicalProcesshormone metabolic process

UGT2B4 UGT2B15 UGT2B17 ACE UGT2A3

1.94e-04286395GO:0042445
GeneOntologyBiologicalProcessregulation of hormone levels

UGT2B4 UGT2B15 UGT2B17 HCAR2 ACE UGT2A3 CCKAR

2.61e-04684397GO:0010817
GeneOntologyBiologicalProcessvery-low-density lipoprotein particle assembly

SOAT2 SOAT1

3.12e-0414392GO:0034379
GeneOntologyBiologicalProcesscellular catabolic process

UGT2B4 MPST UGT2B15 UGT2B17 ROCK1 LRBA TST ACE GSTO1

4.42e-041253399GO:0044248
GeneOntologyBiologicalProcesssulfur compound metabolic process

XYLT1 MPST TST TM9SF2 GSTO1

5.93e-04365395GO:0006790
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

UGT2B4 GATM MPST UGT2B15 UGT2B17 TST GSTO1 UGT2A3

6.00e-041035398GO:0019752
GeneOntologyBiologicalProcesskidney development

LRP2 GATM MPST ACE PRKX

6.46e-04372395GO:0001822
GeneOntologyBiologicalProcessoxoacid metabolic process

UGT2B4 GATM MPST UGT2B15 UGT2B17 TST GSTO1 UGT2A3

6.93e-041058398GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

UGT2B4 GATM MPST UGT2B15 UGT2B17 TST GSTO1 UGT2A3

7.19e-041064398GO:0006082
GeneOntologyBiologicalProcessrenal system development

LRP2 GATM MPST ACE PRKX

7.63e-04386395GO:0072001
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT2B4 UGT2B15 UGT2B17 GSTO1

8.00e-04222394GO:0071466
GeneOntologyBiologicalProcessangiotensin-activated signaling pathway

ROCK1 ACE

9.37e-0424392GO:0038166
GeneOntologyBiologicalProcesslipid storage

APOC4 SOAT2 SOAT1

1.03e-03105393GO:0019915
GeneOntologyBiologicalProcesscholesterol storage

SOAT2 SOAT1

1.10e-0326392GO:0010878
GeneOntologyCellularComponentnuclear membrane

UGT2B4 UGT2B15 UGT2B17 GSTO1 MACO1 GRK5

3.65e-05349386GO:0031965
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B15 UGT2B17

5.23e-0540383GO:0005640
GeneOntologyCellularComponentendoplasmic reticulum membrane

UGT2B4 CYP4X1 UGT2B15 UGT2B17 LRBA MOGAT1 DERL1 SOAT2 MACO1 SOAT1

7.59e-0512933810GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

UGT2B4 CYP4X1 UGT2B15 UGT2B17 LRBA MOGAT1 DERL1 SOAT2 MACO1 SOAT1

7.89e-0512993810GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

UGT2B4 CYP4X1 UGT2B15 UGT2B17 LRBA MOGAT1 DERL1 SOAT2 MACO1 SOAT1

9.43e-0513273810GO:0042175
GeneOntologyCellularComponentbrush border

TRPM6 LRP2 ACE SOAT2

1.64e-04152384GO:0005903
GeneOntologyCellularComponentorganelle envelope

UGT2B4 GATM MPST UGT2B15 UGT2B17 TST GSTO1 MACO1 GRK5 AFG3L2

1.80e-0414353810GO:0031967
GeneOntologyCellularComponentbrush border membrane

TRPM6 LRP2 ACE

4.61e-0483383GO:0031526
GeneOntologyCellularComponentnuclear envelope

UGT2B4 UGT2B15 UGT2B17 GSTO1 MACO1 GRK5

4.79e-04560386GO:0005635
GeneOntologyCellularComponentmitochondrial inner membrane

GATM MPST UGT2B15 UGT2B17 TST AFG3L2

6.47e-04593386GO:0005743
GeneOntologyCellularComponentcluster of actin-based cell projections

TRPM6 LRP2 ACE SOAT2

7.00e-04223384GO:0098862
GeneOntologyCellularComponentorganelle inner membrane

GATM MPST UGT2B15 UGT2B17 TST AFG3L2

1.06e-03652386GO:0019866
DomainUDPGT

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.50e-0821384PS00375
DomainUDPGT

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.50e-0821384PF00201
DomainUDP_glucos_trans

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.50e-0821384IPR002213
DomainSterol_acyltranf_meta

SOAT2 SOAT1

4.03e-062382IPR030687
DomainRHODANESE_2

MPST TST

4.03e-062382PS00683
DomainRHODANESE_1

MPST TST

4.03e-062382PS00380
DomainThiosulphate_STrfase_CS

MPST TST

1.21e-053382IPR001307
DomainOat_ACAT_DAG_ARE

SOAT2 SOAT1

1.21e-053382IPR014371
DomainAGC-kinase_C

ROCK1 PRKX GRK5

2.00e-0456383IPR000961
DomainAGC_KINASE_CTER

ROCK1 PRKX GRK5

2.00e-0456383PS51285
DomainS_TK_X

ROCK1 PRKX GRK5

2.00e-0456383SM00133
DomainMBOAT_fam

SOAT2 SOAT1

2.19e-0411382IPR004299
DomainMBOAT

SOAT2 SOAT1

2.19e-0411382PF03062
DomainRHOD

MPST TST

9.08e-0422382SM00450
DomainRHODANESE_3

MPST TST

9.93e-0423382PS50206
DomainRhodanese-like_dom

MPST TST

1.08e-0324382IPR001763
Domain-

MPST TST

1.08e-03243823.40.250.10
DomainRhodanese

MPST TST

1.08e-0324382PF00581
Domain-

LRP2 TENM2

2.85e-03393822.120.10.30
Domain6-blade_b-propeller_TolB-like

LRP2 TENM2

3.94e-0346382IPR011042
DomainKinase-like_dom

TRPM6 ROCK1 PRKX PRKY GRK5

4.60e-03542385IPR011009
DomainSer/Thr_kinase_AS

ROCK1 PRKX PRKY GRK5

5.80e-03357384IPR008271
DomainS_TKc

ROCK1 PRKX PRKY GRK5

5.92e-03359384SM00220
DomainPROTEIN_KINASE_ST

ROCK1 PRKX PRKY GRK5

6.09e-03362384PS00108
DomainPkinase

ROCK1 PRKX PRKY GRK5

7.28e-03381384PF00069
DomainPROTEIN_KINASE_ATP

ROCK1 PRKX PRKY GRK5

1.37e-02459384PS00107
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.90e-0724344MM14599
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.44e-0725344M17787
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.44e-0725344MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.44e-0725344M605
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2A3

4.06e-0726344M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B4 UGT2B15 UGT2B17 UGT2A3

5.54e-0728344M19580
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

6.50e-0770345M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

7.49e-0772345M9257
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.68e-0641344M7399
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.58e-0644344M45014
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.92e-0645344MM15694
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT2B4 CYP4X1 UGT2B15 UGT2B17 GSTO1 UGT2A3

4.38e-06183346M39588
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

5.36e-06107345MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

5.87e-06109345M18788
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT2B4 UGT2B15 UGT2B17 UGT2A3

6.50e-0651344M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2A3

7.03e-0652344M14171
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.82e-0655344M14933
PathwayKEGG_RETINOL_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.62e-0564344M9488
PathwayREACTOME_PREDNISONE_ADME

UGT2B4 UGT2B15 UGT2B17

2.20e-0523343MM16639
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

APOC4 SOAT2 SOAT1

7.29e-0534343MM15566
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

APOC4 SOAT2 SOAT1

9.42e-0537343M27847
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B15 UGT2B17

1.10e-0439343MM15695
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.31e-04109344M45012
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

1.67e-04219345MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

1.70e-04220345M10320
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.84e-04119344MM15692
PathwayREACTOME_DEGRADATION_OF_CYSTEINE_AND_HOMOCYSTEINE

MPST TST

4.33e-0413342MM14618
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

APOC4 SOAT2 SOAT1

4.40e-0462343MM14686
PathwayREACTOME_DEGRADATION_OF_CYSTEINE_AND_HOMOCYSTEINE

MPST TST

5.81e-0415342M26981
PathwayKEGG_STEROID_BIOSYNTHESIS

SOAT2 SOAT1

7.51e-0417342M5872
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

APOC4 SOAT2 SOAT1

7.69e-0475343M27032
PathwayREACTOME_LDL_CLEARANCE

SOAT2 SOAT1

8.43e-0418342MM15565
PathwayREACTOME_LDL_CLEARANCE

SOAT2 SOAT1

9.41e-0419342M27846
PathwayWP_CHEMOKINE_SIGNALING_PATHWAY

ROCK1 PRKX PRKY GRK5

9.59e-04184344MM15943
PathwayREACTOME_SULFUR_AMINO_ACID_METABOLISM

MPST TST

1.51e-0324342MM14619
PathwayREACTOME_SULFUR_AMINO_ACID_METABOLISM

MPST TST

2.05e-0328342M547
PathwayWP_DYSREGULATED_MIRNA_TARGETING_IN_INSULINPI3KAKT_SIGNALING

PRKX PRKY

2.05e-0328342MM15957
PathwayWP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19

ROCK1 ACE

2.20e-0329342M40051
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

APOC4 KDM1B

3.57e-0337342M29790
PathwayREACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS

ROCK1 SPTAN1

3.57e-0337342MM14488
PathwayREACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS

ROCK1 SPTAN1

3.76e-0338342M495
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B15 UGT2B17

4.55e-08739326074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B15 UGT2B17

7.27e-08839332093886
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B4 UGT2B15 UGT2B17

7.27e-08839318719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B4 UGT2B15 UGT2B17

7.27e-08839320142249
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B4 UGT2B15 UGT2B17

2.85e-071239320308471
Pubmed

The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.

PRKX PRKY

1.23e-0623927633447
Pubmed

Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies.

SOAT2 SOAT1

1.23e-06239215992359
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

1.23e-06239232660355
Pubmed

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.

SOAT2 SOAT1

1.23e-06239226982734
Pubmed

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.

SOAT2 SOAT1

1.23e-06239216647063
Pubmed

Man to mouse--lessons learned from the distal end of the human X chromosome.

PRKX PRKY

1.23e-0623929414316
Pubmed

Profiles of PrKX expression in developmental mouse embryo and human tissues.

PRKX PRKY

1.23e-06239215879576
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

1.23e-0623921909870
Pubmed

Organization of human ACAT-2 gene and its cell-type-specific promoter activity.

SOAT2 SOAT1

1.23e-06239211401500
Pubmed

Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).

SOAT2 SOAT1

1.23e-06239218000807
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

1.23e-06239224121496
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

1.23e-0623923117546
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

1.23e-06239224267955
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

1.23e-06239222170718
Pubmed

Expression of two isozymes of acyl-coenzyme A: cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma.

SOAT2 SOAT1

1.23e-06239218269457
Pubmed

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

SOAT2 SOAT1

1.23e-06239222811412
Pubmed

Low expression of thiosulfate sulfurtransferase (rhodanese) predicts mortality in hemodialysis patients.

MPST TST

1.23e-06239219695240
Pubmed

Quantitative analysis of the expression of ACAT genes in human tissues by real-time PCR.

SOAT2 SOAT1

1.23e-06239214729857
Pubmed

PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.

PRKX PRKY

1.23e-06239221684272
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

1.23e-0623923105095
Pubmed

Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.

PRKX PRKY

1.23e-0623929302280
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

1.23e-06239217848572
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

1.23e-06239227496708
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

1.23e-06239228228532
Pubmed

The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G-->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects.

SOAT2 SOAT1

1.23e-06239215158756
Pubmed

A novel murine PKA-related protein kinase involved in neuronal differentiation.

PRKX PRKY

1.23e-06239210729225
Pubmed

Ability of serum to decrease cellular acylCoA:cholesterol acyl transferase activity predicts cardiovascular outcomes.

SOAT2 SOAT1

1.23e-06239216230498
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

1.23e-06239215666817
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

1.23e-06239217698910
Pubmed

Proteomic analysis of the mouse liver mitochondrial inner membrane.

MPST UGT2B15 UGT2B17 TST AFG3L2

1.53e-0617539512865426
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

APOC4 ACE SOAT2 SOAT1 CCKAR

2.41e-0619239520602615
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17

3.67e-06339219572376
Pubmed

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

SOAT2 SOAT1

3.67e-0633929756920
Pubmed

Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.

PRKX PRKY

3.67e-06339217980165
Pubmed

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

UGT2B15 UGT2B17

3.67e-06339226163549
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B15

3.67e-0633927835904
Pubmed

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

UGT2B15 UGT2B17

3.67e-06339220736324
Pubmed

FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12-->q13.

PRKX PRKY

3.67e-0633929154127
Pubmed

Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.

UGT2B15 UGT2B17

3.67e-06339226385605
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B17

3.67e-06339229138287
Pubmed

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

UGT2B15 UGT2B17

3.67e-06339228882566
Pubmed

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.

UGT2B15 UGT2B17

3.67e-06339217988216
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B15 UGT2B17

3.67e-06339223223495
Pubmed

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

UGT2B15 UGT2B17

3.67e-06339218302198
Pubmed

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

UGT2B15 UGT2B17

3.67e-06339230689982
Pubmed

ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation.

SOAT2 SOAT1

7.34e-06439222669916
Pubmed

Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase.

SOAT2 SOAT1

7.34e-06439222474282
Pubmed

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

SOAT2 SOAT1

7.34e-06439220133765
Pubmed

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

UGT2B15 UGT2B17

7.34e-06439218281521
Pubmed

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells.

SOAT2 SOAT1

7.34e-06439215308631
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B15 UGT2B17

7.34e-06439226176234
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT2B4 UGT2B15

1.22e-05539215318931
Pubmed

Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase.

MOGAT1 SOAT2

1.22e-05539212077311
Pubmed

Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.

UGT2B15 UGT2B17

1.83e-05639221365123
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP2 SOAT2 CCKAR

2.04e-054739311208732
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

EN2 TENM2

2.56e-05739210625539
Pubmed

Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.

UGT2B4 UGT2B15

2.56e-05739216513443
Pubmed

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

SOAT2 SOAT1

3.42e-0583929756919
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT2B15 UGT2B17

3.42e-05839222579593
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT2B4 UGT2B15

3.42e-05839210748067
Pubmed

Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes.

HCAR2 ACE

3.42e-05839218787507
Pubmed

Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing.

PRKX PRKY

3.42e-05839222641646
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

LRP2 ACE

6.70e-051139222999937
Pubmed

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.

CYP4X1 UGT2B15 UGT2B17 ACE

7.03e-0519739421386911
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ROCK1 KDM1B LRBA GSTO1 SPTAN1 AFG3L2

7.70e-0564539625281560
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT2B4 UGT2B15

8.03e-051239218161889
Pubmed

Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants.

APOC4 SOAT1

1.27e-041539216763159
Pubmed

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.

TM9SF2 DERL1 SOAT1 AFG3L2

1.39e-0423539432614325
Pubmed

Executioner caspase-3 and caspase-7 are functionally distinct proteases.

ROCK1 SPTAN1

1.65e-041739218723680
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT2B4 UGT2B15

1.85e-041839220056724
Pubmed

Perioperative genomic profiles using structure-specific oligonucleotide probes.

ACE PRKY

3.05e-042339219474452
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

GATM ACE

3.33e-042439224625756
Pubmed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

LRP2 UGT2A3

4.23e-042739228167773
Pubmed

Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

LRP2 GATM GSTO1

4.42e-0413239322496890
Pubmed

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

LRP2 SOAT1

5.58e-043139220031551
Pubmed

Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head.

LRP2 EN2

7.96e-043739223592779
Cytoband4q13

UGT2B4 UGT2B15 UGT2B17

2.56e-07153934q13
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B4 UGT2B15 UGT2B17 UGT2A3

9.86e-06157394chr4q13
Cytoband12q24.31

HCAR2 DNAH10

2.13e-038039212q24.31
Cytoband22q13.1

MPST TST

2.40e-038539222q13.1
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.38e-0732274363
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

UGT2B4 GATM UGT2B15 UGT2B17 HCAR2

9.80e-07121395MM935
CoexpressionHSIAO_LIVER_SPECIFIC_GENES

UGT2B4 GATM UGT2B15 APOC4 TST GSTO1

1.74e-06249396M13283
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 SOAT2 UGT2A3

1.18e-05201395MM1294
CoexpressionGUILLAUMOND_KLF10_TARGETS_UP

UGT2B15 UGT2B17 DERL1

9.35e-0559393MM952
CoexpressionDESCARTES_FETAL_LIVER_HEPATOBLASTS

UGT2B4 UGT2B15 APOC4 MOGAT1 SOAT2 UGT2A3

9.44e-05505396M40234
CoexpressionCHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_LD_MTX_UP

TM9SF2 PRKY

9.63e-0510392M11031
CoexpressionHOFFMAN_CLOCK_TARGETS_UP

UGT2B15 UGT2B17

9.63e-0510392M2063
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

1.24e-04330395MM1120
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

UGT2B4 UGT2B15 UGT2B17 APOC4 TST SOAT2

1.29e-04535396MM3635
CoexpressionBUSSLINGER_DUODENAL_LATE_IMMATURE_ENTEROCYTES

GATM UGT2B17 ACE UGT2A3

1.37e-04177394M40028
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.80e-04190394MM1311
CoexpressionGSE15659_RESTING_VS_ACTIVATED_TREG_DN

TRPM6 UGT2B17 ROCK1 PRKX

2.11e-04198394M3563
CoexpressionGSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN

TRPM6 UGT2B17 ROCK1 PRKX

2.15e-04199394M3560
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST ACE CCKAR

3.35e-071663958ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST ACE CCKAR

3.55e-07168395dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST ACE CCKAR

3.88e-0717139505fcc72df50a380a913821b5781d9621df37d328
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST ACE CCKAR

3.88e-0717139548fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

7.61e-071963953cf73ed99f3efa76b632c16a8b98b6b7758ff63f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.00e-07198395a9d72b17adfddb6ac1857c5f094280e86582693b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.00e-07198395b933bd66f544822fcf1f2aa2d928c31500e2b3f4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.00e-0719839572733b6149b797ac11cc108bc80428b77fbbba78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.00e-07198395f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.41e-07200395234e5a927eec0e235226586451ba3754c8a14169
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM MPST TST UGT2A3

8.41e-07200395e118d5e6e5d5bb808877a6667668c36f21afad5b
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CYP4X1 LRBA DNAH10 PRKY

1.04e-0515639410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST CCKAR

1.30e-05165394082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST CCKAR

1.33e-051663940868f45d8d39ad39b5cee5e81ac3dd4dc512775d
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-CLDN10+_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATM UGT2B15 UGT2A3 CCKAR

1.79e-051793947eca1e19ae6b5b1f18c721691dc3e860705628f2
ToppCellThalamus-Macroglia|Thalamus / BrainAtlas - Mouse McCarroll V32

GATM MPST TST EN2

1.87e-051813944f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 GSTO1 TENM2 CCKAR

1.87e-051813944a0f1b121570430afb100c589657d931184e124f
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 GSTO1 TENM2 CCKAR

1.87e-0518139434b49092f71128898af3b311170c4ed8adfefcff
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 GSTO1 TENM2 CCKAR

1.91e-05182394f8eb35eb7f2b8ad47d527ae9ff8a9ddbcd2eedce
ToppCellfacs-Lung-EPCAM-18m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 GSTO1 TENM2 CCKAR

1.91e-051823946685a0abd9c3a79d03b6a578e5d7fa86a9d74117
ToppCellIPF-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

XYLT1 APOBEC3G PRKX PRKY

1.91e-05182394f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 MOGAT1 ACE UGT2A3

1.95e-05183394d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 GATM MOGAT1 UGT2A3

1.95e-051833946878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

XYLT1 APOBEC3G PRKX PRKY

1.95e-0518339449bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 GATM MOGAT1 UGT2A3

1.99e-0518439451ed1ebfdef45149541917c66cbacad87072e51f
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.65e-05198394e3e2233c796d5e9051c8c1b66f70f406f048ed56
ToppCellCOVID-19-kidney-PCT-S3-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 GATM TST UGT2A3

2.65e-0519839436a60397f49f5381ae377155b73e1891448846b7
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.65e-05198394222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCell3'-Child09-12-SmallIntestine-Epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.71e-05199394043c65bdf54a1bf0e483fea9ffc042ff5b271764
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.71e-051993940181c13379f869be47804cdb11bbdabcd30b9b23
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM TST UGT2A3

2.71e-051993944bde35e5df019189433d65d415e29a0c1145ac66
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.71e-05199394ee981046217e8759610eb58a670d98f32cd83abc
ToppCell3'-Child04-06-SmallIntestine-Epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPST UGT2B17 ACE UGT2A3

2.71e-05199394ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell5'-Adult-LargeIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 MPST UGT2B17 TST

2.76e-052003943f29823952a4303451997dd5177a51179bd20540
ToppCell5'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM6 MPST UGT2B17 TST

2.76e-05200394b2fa6e44ace5897766792ed97ffafc11555175e7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 GATM TST UGT2A3

2.76e-05200394825aad08431dd6b54aa636ace6efc821dfaf8014
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATM TST CCKAR

8.39e-059739316947da747504c2edb9f2e7ee6f05babda0fae60
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPM6 HCAR2 GRK5

2.04e-0413139396d300958545714d18e905e860e95469c8ae4efa
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MOGAT1 POLQ DNAH10

2.09e-0413239302491930097b75aaeedab9e8200711b0dc610944
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM6 LRP2 ACE

2.70e-041443931b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 HCAR2 ACE

3.04e-0415039334774b015adecc2be56a471fda8994e89a6ad93e
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOC4 TST UGT2A3

3.10e-04151393cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOC4 TST UGT2A3

3.10e-041513937758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOC4 TST UGT2A3

3.10e-04151393b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOC4 TST UGT2A3

3.16e-041523931febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOC4 TST UGT2A3

3.16e-04152393faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRIT2 APOC4 TST

3.60e-041593930f6ff73410fd6a6f97a53cb865952963a73848dd
ToppCelldroplet-Lung-nan-21m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE GSTO1 GRK5

3.67e-041603934738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCelldroplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE GSTO1 GRK5

3.67e-041603930b8151037b28f52a21918856a1e9336e8d5edb90
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZSWIM9 HCAR2 TST

3.67e-0416039370f3637dd0bcfcef421aa114f946fff0048f192e
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATM MOGAT1 CCKAR

3.74e-04161393b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATM MOGAT1 CCKAR

3.74e-04161393f7a89c481f789f624102857be722c95fbeb47595
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 EN2 UGT2A3

3.74e-04161393b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPST TST GSTO1

3.95e-041643932a00515d91ea03efcfc2a3d3c805dc2711867fcd
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TST GSTO1 CCKAR

4.02e-04165393baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCellClub-club-12|World / Class top

TST GSTO1 CCKAR

4.02e-041653939b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TST GSTO1 CCKAR

4.02e-041653936fdce8b23736409a23884ef3918638ffc067a86f
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TST GSTO1 CCKAR

4.02e-04165393dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATM SOAT2 CCKAR

4.09e-04166393b7f303203068b205f382788815df487a0ea148ed
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.09e-04166393021b9344de7957762f81b09a647504b8c8289cf1
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.16e-04167393ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4X1 SOAT2 GRK5

4.23e-041683934b2d29a7843bf45922038c093ca7ec0600756adc
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.31e-04169393f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.31e-0416939353e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCellP07-Epithelial-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.31e-04169393ec23caecbb0d969307e33e9df8499ddcd1420305
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.38e-041703936c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TST GSTO1 CCKAR

4.38e-041703936de3778e8257c3330db0780c59238ca501fe5059
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRPM6 LRP2 SOAT1

4.38e-04170393d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.38e-041703933fd37e9b377d6485cea1262c31a8507d18a78514
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TST GSTO1 CCKAR

4.38e-0417039360887da674ef1a735bad618235608312d8de63d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4X1 SOAT2 GRK5

4.46e-041713935d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

CYP4X1 HCAR2 TM9SF2

4.46e-04171393adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.46e-04171393007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.46e-041713938e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCellfacs-Trachea-nan-24m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 TST GSTO1

4.46e-04171393d2a10e94b0490120d1420b944302eb841f902c64
ToppCellIonocyte-iono-2|World / Class top

ACE GRK5 SOAT1

4.61e-04173393e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 ACE GRK5

4.61e-04173393c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCellSubstantia_nigra-Macroglia|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GATM MPST TST

4.69e-041743937e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

UGT2B4 UGT2B15 APOC4

4.69e-04174393452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 TST SOAT1

4.77e-041753938a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.77e-04175393076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MOGAT1 TST

4.77e-0417539313843bfc8efe7c01f19ebb6735609c1eec09c698
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MPST ACE

4.77e-04175393445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellfacs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 TST GSTO1

4.77e-04175393eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LRP2 TST SOAT1

4.85e-04176393ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

TST GSTO1 CCKAR

4.85e-04176393cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 LRP2 CCKAR

4.85e-041763935201f003192c033655ba47f0faf8c47a96eae03d
ToppCelldroplet-Kidney-nan-21m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GATM TM9SF2

4.85e-041763930475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCellfacs-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GATM MPST

4.93e-041773937f58286fc8797e9bdcf8ece0849f55680905955d
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GATM MPST

4.93e-04177393d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GATM UGT2A3

4.93e-041773932bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GATM UGT2A3

4.93e-041773939c7c6824b9011363851f084a500d665f025b026e
ToppCellControl-Lymphoid-ILC_B|Control / Disease state, Lineage and Cell class

XYLT1 PRKX PRKY

4.93e-041773933d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 LRP2 CCKAR

5.01e-0417839376e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 LRP2 CCKAR

5.01e-041783935442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 MOGAT1 UGT2A3

5.01e-0417839323a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 DNAH10 TENM2

5.01e-04178393c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 LRP2 CCKAR

5.01e-0417839382f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 LRP2 CCKAR

5.01e-04178393523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellGlobus_pallidus-Macroglia|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GATM TST EN2

5.09e-04179393ab50f711b004b96107f813c9a2526ec21d1c8027
Drugsodium cholate

UGT2B4 LRP2 UGT2B15 UGT2B17 APOC4 SOAT2 UGT2A3 SOAT1 CCKAR

1.80e-08408389CID000000303
DrugC1 11-32

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.98e-0818384CID000443077
DrugC11131

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.98e-0818384CID000443076
DrugT4-G

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.51e-0819384CID000152424
Drugclofibrate

UGT2B4 CYP4X1 UGT2B15 UGT2B17 APOC4 GSTO1 SOAT2 SOAT1

3.79e-08311388CID000002796
Drugestriol-16-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.87e-0821384CID000122281
DrugNSC-110264

LRBA SOAT2 SOAT1

4.28e-085383CID000269324
DrugUDP-alpha-d-xylopyranose

XYLT1 UGT2B4 UGT2B15 UGT2B17 UGT2A3

5.03e-0860385CID000001165
Drugestradiol-3-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

5.71e-0823384CID000066651
DrugL-idaro-1,4-lactone

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.31e-0728384CID000078997
Drug2,2,2-trichloroethanol

UGT2B4 CYP4X1 UGT2B15 UGT2B17 UGT2A3

1.36e-0773385CID000008259
Drug7-hydroxycoumarin glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.52e-0729384CID000125641
DrugAC1Q6OQG

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.61e-0733384CID000009686
DrugAC1NOWCJ

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.33e-0735384CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.33e-0735384CID010436171
Drugestrone-3-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.33e-0735384CID000115255
Drugaminopyrine

UGT2B4 CYP4X1 UGT2B15 UGT2B17 APOC4 UGT2A3

3.72e-07171386CID000006009
Drug2-naphthol

UGT2B4 CYP4X1 UGT2B15 UGT2B17 UGT2A3

4.60e-0793385CID000008663
Drugharmol

UGT2B4 UGT2B15 UGT2B17 UGT2A3

5.77e-0740384CID000068094
Drugtestosterone glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

6.39e-0741384CID000108192
Drug2-AF

UGT2B4 UGT2B15 UGT2B17 UGT2A3

6.39e-0741384CID000005800
Drugacetylshikonin

LRBA SOAT2 SOAT1

7.01e-0711383CID000032464
Drug1,4-benzodiazepine

UGT2B4 UGT2B15 CCKAR

7.01e-0711383CID000148431
Drugandrosterone glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2A3

7.77e-0743384CID000114833
Drugtryptophan-leucine

ACE SOAT2 SOAT1

1.21e-0613383CID000323786
DrugAC1Q7AUJ

UGT2B4 CYP4X1 UGT2B15 UGT2B17 UGT2A3

1.44e-06117385CID000003303
DrugAC1NQGK1

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.69e-0652384CID005195977
Drugoxazepam

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.82e-0653384CID000004616
Drugphenobarbital

UGT2B4 CYP4X1 UGT2B15 UGT2B17 APOC4 GSTO1 UGT2A3

1.93e-06360387CID000004763
Drughexobarbital

UGT2B4 CYP4X1 UGT2B15 UGT2B17 UGT2A3

2.16e-06127385CID000003608
Drug7-methoxycoumarin

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.44e-0657384CID000010748
Drug4-methylumbelliferone

UGT2B4 UGT2B15 UGT2B17 APOC4 UGT2A3

2.61e-06132385CID003364573
Drugphenolphthalein

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.62e-0658384CID000004764
Drugdeserpidine

LRBA ACE

2.71e-062382CID000008550
DrugAC1Q6A3R

SOAT2 SOAT1

2.71e-062382CID000160583
Druggypsetin

SOAT2 SOAT1

2.71e-062382CID000160406
Drugglisoprenin B

SOAT2 SOAT1

2.71e-062382CID006438769
DrugNSC292654

SOAT2 SOAT1

2.71e-062382CID000325064
Drug23-methyl-UDCA

SOAT2 SOAT1

2.71e-062382CID000196679
Drug7,7-difluorocholestanol

SOAT2 SOAT1

2.71e-062382CID000196646
Drug6,6-difluorocholestanol

SOAT2 SOAT1

2.71e-062382CID000196647
DrugAplus

SOAT2 SOAT1

2.71e-062382CID000028221
DrugRo 16-0521

SOAT2 SOAT1

2.71e-062382CID000065657
DrugAC1NT076

SOAT2 SOAT1

2.71e-062382CID005321102
Drugxymedon

SOAT2 SOAT1

2.71e-062382CID000121931
Drugurochloralic acid

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.81e-0659384CID003036914
Drug4-hydroxybiphenyl

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.81e-0659384CID000007103
DrugSN-38G

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.81e-0659384CID000443154
DrugMEDICA 16

APOC4 SOAT2 SOAT1

2.87e-0617383CID000121871
Druganethole trithione

UGT2B4 GATM UGT2B15 UGT2B17

3.66e-0663384CID000002194
Drug3-OHBaP

UGT2B4 UGT2B15 UGT2B17 UGT2A3

3.66e-0663384CID000025890
DrugAC1L1OBF

UGT2B4 UGT2B15 UGT2B17

4.79e-0620383CID000032736
Druggemcabene

UGT2B17 APOC4 SOAT2

4.79e-0620383CID000157691
DrugMeldola

UGT2B4 UGT2B15 UGT2B17 UGT2A3

4.97e-0668384CID000081507
DrugAC1L2AC7

LRP2 ACE SOAT2 SOAT1

5.27e-0669384CID000068733
Drugmethoxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2A3

5.27e-0669384CID000119220
Drug17alpha-estradiol

TRPM6 UGT2B4 LRP2 GATM UGT2B15 UGT2B17 HCAR2 APOC4 POLQ ACE UGT2A3

5.93e-0613033811CID000000450
Drugethanol

MPST HCAR2 APOC4 LRBA POLQ ACE GSTO1 SPTAN1 SOAT1

7.33e-06837389CID000000702
Drug7-hydroxycoumarin

UGT2B4 UGT2B15 UGT2B17 UGT2A3

7.36e-0675384CID005281426
Drugolean-12-ene

SOAT2 SOAT1

8.13e-063382CID000612780
DrugPurpactin A

SOAT2 SOAT1

8.13e-063382CID000131673
Drugglisoprenin A

SOAT2 SOAT1

8.13e-063382CID006438768
DrugNsc692258

SOAT2 SOAT1

8.13e-063382CID000469167
Drugethyl 6-chlorochroman-2-carboxylate

SOAT2 SOAT1

8.13e-063382CID000169516
Drugzaragozic acid D3

SOAT2 SOAT1

8.13e-063382CID006475792
Drug16-epiestriol

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.18e-0677384CID000003269
Drugestrone-d4

UGT2B4 UGT2B15 UGT2B17 ACE UGT2A3

8.49e-06168385CID000000698
DrugAC1N8H7N

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.61e-0678384CID004318740
Drugbenzyloxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2A3

8.61e-0678384CID000114982
DrugHymecromone

UGT2B4 UGT2B15 UGT2B17

9.62e-0625383ctd:D006923
Drugoctimibate

APOC4 SOAT2 SOAT1

9.62e-0625383CID000065676
Drugacridine

UGT2B4 UGT2B15 UGT2B17 POLQ

1.00e-0581384CID000009215
DrugAsp-Lys

ACE SOAT2 SOAT1

1.22e-0527383CID000165361
Druglicochalcone A

UGT2B4 UGT2B15 UGT2B17

1.22e-0527383ctd:C070840
DrugSN-38

UGT2B4 UGT2B15 UGT2B17 ROCK1 UGT2A3

1.32e-05184385CID000104842
Drugmenthol

TRPM6 UGT2B4 UGT2B15 UGT2B17

1.33e-0587384CID000001254
Drugpentoxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.33e-0587384CID000107683
DrugDNCB

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

1.50e-05189385CID000000006
Druguridine 5'-diphosphoglucuronic acid

UGT2B4 UGT2B15 UGT2B17 DERL1 UGT2A3

1.50e-05189385CID000000390
Drug3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid

UGT2B4 UGT2B15 UGT2A3

1.52e-0529383CID000006747
Drugpropofol

UGT2B4 UGT2B15 HCAR2 APOC4 ACE

1.58e-05191385CID000004943
DrugCgs-26214

SOAT2 SOAT1

1.62e-054382CID000133077
DrugAC1L3QAA

SOAT2 SOAT1

1.62e-054382CID000093484
Drugisochromophilone VII

SOAT2 SOAT1

1.62e-054382CID006443571
Drugisochromophilone VIII

SOAT2 SOAT1

1.62e-054382CID006443572
Drugacaterin

SOAT2 SOAT1

1.62e-054382CID000126830
DrugDAB sulfinate

MPST TST

1.62e-054382CID000125472
Drug4-aminobiphenyl

UGT2B4 UGT2B15 UGT2B17 GSTO1

1.66e-0592384CID000007102
Drugp-nitroanisole

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.66e-0592384CID000007485
Drugdimethylnitrosamine

UGT2B4 UGT2B15 UGT2B17 UGT2A3 SOAT1

1.79e-05196385CID000006124
DrugDCNB

UGT2B4 UGT2B15 UGT2B17 UGT2A3

1.88e-0595384CID000007443
Drugbeta-naphthoflavone

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

1.97e-05200385CID000002361
DrugNNAL

UGT2B4 UGT2B15 UGT2B17

2.06e-0532383CID000104856
Drug1-naphthol

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.13e-0598384CID000007005
DrugR(-)-Denopamine

UGT2B4 UGT2B15 UGT2B17

2.26e-0533383CID000003818
DrugBP-3,6-quinol

UGT2B4 UGT2B15 UGT2B17

2.26e-0533383CID000119292
Drug3-hydroxyandrostan-17-one

UGT2B4 UGT2B15 UGT2B17 UGT2A3

2.49e-05102384CID000000225
DrugAroclor 1254

UGT2B4 UGT2B15 UGT2B17 GSTO1 UGT2A3

2.67e-05213385CID000040470
DrugAmobarbital

UGT2B4 UGT2B15

2.70e-055382ctd:D000654
Drugphenolphthalin

UGT2B4 UGT2B15

2.70e-055382CID000066494
DiseaseX-19141 measurement

UGT2B4 UGT2B15 UGT2B17

5.15e-0713373EFO_0800799
Diseaseandrosterone glucuronide measurement

UGT2B4 UGT2B15 UGT2B17

2.04e-0620373EFO_0800317
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

UGT2B15 UGT2B17 HCAR2 APOC4 DNAH10 MACO1

2.48e-06315376EFO_0004612, EFO_0008591
DiseaseX-24947 measurement

UGT2B4 UGT2B15 UGT2B17

2.75e-0622373EFO_0800910
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

4.59e-063372EFO_0800574
DiseaseX-25937 measurement

UGT2B15 UGT2B17

9.17e-064372EFO_0800937
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

UGT2B15 UGT2B17 HCAR2 APOC4 DNAH10

1.28e-05243375EFO_0004612, EFO_0020944
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

UGT2B15 UGT2B17 HCAR2 APOC4 DNAH10

2.36e-05276375EFO_0004612, EFO_0020943
DiseaseX-24574 measurement

UGT2B15 UGT2B17

3.20e-057372EFO_0800897
DiseaseX-24418 measurement

UGT2B4 UGT2B15

3.20e-057372EFO_0800879
Diseasecholesteryl ester 24:4 measurement

SOAT2 SOAT1

3.20e-057372EFO_0021447
Diseasevanillylmandelate (VMA) measurement

UGT2B4 UGT2B15

3.20e-057372EFO_0800119
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

4.26e-058372EFO_0800575
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

UGT2B15 UGT2B17 HCAR2 APOC4 DNAH10

4.84e-05321375EFO_0004612, EFO_0004639
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B15

5.48e-059372EFO_0600040
DiseaseX-12844 measurement

UGT2B4 UGT2B15

5.48e-059372EFO_0021339
Diseaselipid measurement, high density lipoprotein cholesterol measurement

UGT2B15 UGT2B17 HCAR2 APOC4 DNAH10

5.52e-05330375EFO_0004529, EFO_0004612
Diseasehigh density lipoprotein particle size measurement

UGT2B15 UGT2B17 APOC4 DNAH10

6.05e-05170374EFO_0008592
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

6.84e-0510372EFO_0022090
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

8.35e-0511372EFO_0801531
Diseasecholesteryl ester 24:5 measurement

SOAT2 SOAT1

1.00e-0412372EFO_0021448
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

1.00e-0412372EFO_0800291
DiseaseProstatic Neoplasms

LRP2 UGT2B15 UGT2B17 TST ACE GSTO1

1.08e-04616376C0033578
DiseaseMalignant neoplasm of prostate

LRP2 UGT2B15 UGT2B17 TST ACE GSTO1

1.08e-04616376C0376358
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

1.18e-0413372EFO_0800293
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

1.38e-0414372EFO_0800283
DiseaseKidney Diseases

LRP2 GATM ACE

1.85e-0488373C0022658
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

2.31e-0418372EFO_0800288
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

2.58e-0419372EFO_0800362
Diseaseend stage renal disease (implicated_via_orthology)

ACE SOAT2

2.87e-0420372DOID:783 (implicated_via_orthology)
Diseasekidney disease (biomarker_via_orthology)

XYLT1 GATM

3.16e-0421372DOID:557 (biomarker_via_orthology)
Diseasenephrosis (biomarker_via_orthology)

LRP2 ACE

3.48e-0422372DOID:2527 (biomarker_via_orthology)
DiseaseCoronary heart disease

ACE MACO1

4.15e-0424372C0010068
Diseaseomega-3 polyunsaturated fatty acid measurement

UGT2B15 UGT2B17 APOC4

4.39e-04118373EFO_0010119
Diseaseepiandrosterone sulfate measurement

UGT2B15 UGT2B17

4.51e-0425372EFO_0021120
Diseasedocosahexaenoic acid measurement

UGT2B15 UGT2B17 APOC4

5.44e-04127373EFO_0007761
Diseasemetabolite measurement

UGT2B4 GATM UGT2B15 UGT2B17 ACE

6.38e-04560375EFO_0004725
Diseaseandrosterone sulfate measurement

UGT2B15 UGT2B17

7.88e-0433372EFO_0021117
DiseaseCardiovascular Diseases

ACE GRK5

9.38e-0436372C0007222
DiseaseParoxysmal atrial fibrillation

KDM1B DNAH10 ACE

9.87e-04156373C0235480
Diseasefamilial atrial fibrillation

KDM1B DNAH10 ACE

9.87e-04156373C3468561
DiseasePersistent atrial fibrillation

KDM1B DNAH10 ACE

9.87e-04156373C2585653
Diseaselysine measurement

MPST TST

9.91e-0437372EFO_0005002
DiseaseAtrial Fibrillation

KDM1B DNAH10 ACE

1.06e-03160373C0004238
DiseaseDegenerative Diseases, Central Nervous System

GSTO1 SPTAN1

1.10e-0339372C0270715
DiseaseDegenerative Diseases, Spinal Cord

GSTO1 SPTAN1

1.10e-0339372C0751733
DiseaseNeurodegenerative Disorders

GSTO1 SPTAN1

1.10e-0339372C0524851
Diseaserisky sexual behaviour measurement

XYLT1 TENM2 GRK5

1.24e-03169373EFO_0007877

Protein segments in the cluster

PeptideGeneStartEntry
SRWFYSPWLLVECYM

ARMT1

106

Q9H993
AFIPFSYLVDQWRWR

ACE

1061

P12821
IPWDDKDFRMFFLWT

AFG3L2

136

Q9Y4W6
WSKFVYSQRELFEPW

APOBEC3G

161

Q9HC16
WMPIFSANAWRAYDT

CCKAR

326

P32238
WFWSPSTFRGFMQTY

APOC4

71

P55056
WFWCPVFREYVMSVG

MOGAT1

146

Q96PD6
SMIDYLIWPWFERLE

GSTO1

171

P78417
EAPMAWRSRFFEYRA

GATM

181

P50440
WTYPLSMWREFDVLT

LRIT2

286

A6NDA9
PFLMDNYVRRWDWKF

HCAR2

81

Q8TDS4
FTFSSYWMSWVRQAP

IGHV3-7

46

P01780
RFEYLWPFWLFIRSV

MACO1

51

Q8N5G2
WPFWLFIRSVYDSFR

MACO1

56

Q8N5G2
DWFRSIPAITRYWFA

DERL1

6

Q9BUN8
SAVSRPLEFWRLDYW

LRBA

1971

P50851
FFTDWFRPAKIMRAW

LRP2

841

P98164
RWSTDPWIQMAYSFV

KDM1B

756

Q8NB78
PMFEDWTTIDWYRFF

POLQ

656

O75417
MEFSWLETRWARPFY

CYP4X1

1

Q8N118
MLWPAWVYCTRYSDR

EN2

211

P19622
YLDSMFFDRFLQWKW

GRK5

161

P34947
FDWESQLRFYWDREP

DNAH10

1766

Q8IVF4
LRFGDRMFYKDWWNS

SOAT1

396

P35610
GLYSAPRVWWMFRAF

MPST

106

P25325
RLFWTWHEERFLYML

PRKY

111

O43930
ERTVWLPWNSFYAMD

TENM2

991

Q9NT68
RFGDRMFYRDWWNST

SOAT2

371

O75908
RDLLEMTDWPWDFFI

XYLT1

406

Q86Y38
WEPRRDMWVRFRAFE

ZSWIM9

381

Q86XI8
SWSLARDIVFEPYWM

TRPM6

1006

Q9BX84
RWAELPKDTFWSYFS

UGT2B4

96

P06133
PYTWFTMEALEETWR

SPTAN1

2166

Q13813
RLFWTWHDERFLYML

PRKX

111

P51817
FWEERDIMAFANSPW

ROCK1

121

Q13464
IRWASRWDYILESMP

TM9SF2

281

Q99805
AEIWLIRTYWDFEFP

UGT2A3

251

Q6UWM9
MWLIRTYWDFEFPRP

UGT2B15

256

P54855
SFYAPRVWWMFRVFG

TST

106

Q16762
MWLIRTYWDFEFPRP

UGT2B17

256

O75795