Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF410 ZNF138 ZNF117 ZNF613 PATZ1 ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 STOX1 ADNP ZNF418 EPAS1 ZFP37 ZNF367

9.95e-0514597616GO:0000977
DomainZnf_C2H2

ZNF410 ZNF385D ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 TUT7 SCAPER ZNF727 ZNF385B ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

3.31e-118057520IPR007087
DomainZnf_C2H2-like

ZNF410 ZNF385D ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 SCAPER ZNF727 ZNF385B ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

2.24e-107967519IPR015880
DomainZnF_C2H2

ZNF410 ZNF385D ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 SCAPER ZNF727 ZNF385B ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

2.88e-108087519SM00355
DomainZINC_FINGER_C2H2_1

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 TUT7 SCAPER ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

1.18e-097777518PS00028
DomainZINC_FINGER_C2H2_2

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 SCAPER ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

8.35e-097757517PS50157
DomainZnf_C2H2/integrase_DNA-bd

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37 ZNF367

1.23e-086947516IPR013087
Domainzf-C2H2_6

ZNF117 ZNF613 ZNF155 PATZ1 ZNF727 ZNF736 ZNF619 ZNF30 ZNF418 ZFP37 ZNF367

4.79e-083147511PF13912
Domain-

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ZNF418 ZFP37 ZNF367

6.60e-0867975153.30.160.60
Domainzf-C2H2

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ADNP ZNF418 ZFP37

8.61e-086937515PF00096
DomainZnF_U1

ZNF385D TUT7 SCAPER ZNF385B

5.28e-0629754SM00451
DomainZnf_U1

ZNF385D TUT7 SCAPER ZNF385B

5.28e-0629754IPR003604
DomainKRAB

ZNF613 ZNF155 ZNF727 ZNF736 ZNF510 ZNF30 ZNF230 ZNF418 ZFP37

1.30e-05358759PS50805
DomainKRAB

ZNF613 ZNF155 ZNF727 ZNF736 ZNF510 ZNF30 ZNF230 ZNF418 ZFP37

1.30e-05358759PF01352
DomainKRAB

ZNF613 ZNF155 ZNF727 ZNF736 ZNF510 ZNF30 ZNF230 ZNF418 ZFP37

1.66e-05369759SM00349
DomainKRAB

ZNF613 ZNF155 ZNF727 ZNF736 ZNF510 ZNF30 ZNF230 ZNF418 ZFP37

1.69e-05370759IPR001909
DomainTSP_3

THBS1 THBS2

1.58e-045752PF02412
DomainTSP3

THBS1 THBS2

1.58e-045752PS51234
DomainTSP_CTER

THBS1 THBS2

1.58e-045752PS51236
Domain-

THBS1 THBS2

1.58e-0457524.10.1080.10
DomainThrombospondin_C

THBS1 THBS2

1.58e-045752IPR008859
DomainTSP_C

THBS1 THBS2

1.58e-045752PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2

1.58e-045752IPR017897
DomainThrombospondin_3-like_rpt

THBS1 THBS2

1.58e-045752IPR003367
DomainTSP_type-3_rpt

THBS1 THBS2

1.58e-045752IPR028974
DomainZnf_C2H2_matrin

ZNF385D ZNF385B

1.02e-0312752IPR000690
DomainZF_MATRIN

ZNF385D ZNF385B

2.34e-0318752PS50171
DomainZnf_C2H2_jaz

ZNF385D ZNF385B

3.49e-0322752IPR022755
Domainzf-C2H2_jaz

ZNF385D ZNF385B

3.49e-0322752PF12171
DomainTSPN

THBS1 THBS2

3.81e-0323752SM00210
DomainTransl_B-barrel

EEFSEC AARS1

5.23e-0327752IPR009000
DomainVWC

THBS1 THBS2

5.62e-0328752PF00093
DomainUbiquitin-rel_dom

PTPN13 SACS MYO9A PIK3CA

6.43e-03184754IPR029071
DomainSNF2_N

ERCC6L2 CHD6

7.30e-0332752IPR000330
DomainSNF2_N

ERCC6L2 CHD6

7.30e-0332752PF00176
DomainDNA/RNA_helicase_DEAH_CS

ERCC6L2 CHD6

8.69e-0335752IPR002464
DomainVWFC_1

THBS1 THBS2

9.18e-0336752PS01208
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

4.84e-06277216181801
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

4.84e-06277217620335
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

4.84e-06277223660684
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

4.84e-06277239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

4.84e-06277234425286
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

4.84e-06277222930728
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

4.84e-0627728126073
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

4.84e-06277238339060
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

4.84e-06277233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

4.84e-06277221762961
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

4.84e-0627729694593
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

4.84e-06277212213711
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

4.84e-06277212358136
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

4.84e-0627721712771
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

4.84e-06277210027393
Pubmed

Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.

THBS1 EPAS1

4.84e-06277231710666
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

4.84e-06277233981184
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

4.84e-06277218594557
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

4.84e-06277215037577
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

4.84e-06277230928339
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

4.84e-06277217143334
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

4.84e-06277233759165
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

1.45e-05377226241338
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2

1.45e-0537729373030
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

1.45e-05377218787106
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

THBS1 THBS2

1.45e-05377218032585
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

1.45e-05377219818485
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

1.45e-05377217638877
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

1.45e-05377230939949
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

1.45e-05377217442977
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

1.45e-05377219004835
Pubmed

Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.

THBS1 THBS2

1.45e-0537728463250
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2

1.45e-05377212482844
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2

1.45e-05377226168731
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

1.45e-05377216598380
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

1.45e-05377227513329
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

1.45e-05377215347840
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2

1.45e-05377225976449
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

1.45e-05377231092423
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2

1.45e-05377234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2

1.45e-0537721459996
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2

1.45e-05377218178577
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2

1.45e-0537728400410
Pubmed

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway.

PIK3CA WNT5A

1.45e-05377221209903
Pubmed

Cocaine Triggers Astrocyte-Mediated Synaptogenesis.

THBS1 THBS2

1.45e-05377233069367
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS1 THBS2

2.89e-05477219147503
Pubmed

TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition.

TET2 EPAS1

2.89e-05477232234487
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2

2.89e-0547726338048
Pubmed

Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.

THBS1 THBS2

2.89e-05477218089612
Pubmed

Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population.

XIRP1 SCN5A

2.89e-05477229306897
Pubmed

Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.

THBS1 THBS2

2.89e-05477212909644
Pubmed

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.

THBS1 THBS2

2.89e-05477211980922
Pubmed

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.

THBS1 THBS2

2.89e-05477210900205
Pubmed

Spontaneous bacterial keratitis in CD36 knockout mice.

THBS1 THBS2

2.89e-05477220847111
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2

4.82e-05577230622267
Pubmed

TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.

THBS1 EPAS1

4.82e-05577228555642
Pubmed

Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.

THBS1 THBS2

4.82e-05577223806329
Pubmed

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.

THBS1 EPAS1

7.22e-05677226503986
Pubmed

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

SPTLC3 LORICRIN WNT5A

7.68e-053777329044125
Pubmed

Osteoclasts adapt to physioxia perturbation through DNA demethylation.

TET2 EPAS1

1.01e-04777234661337
Pubmed

Jarid2 regulates mouse epidermal stem cell activation and differentiation.

JARID2 LORICRIN

1.01e-04777221811233
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SPTLC3 PTPN13 MYO9A ARHGAP44 BANP SEL1L3 KCNMA1 ZNF385B CHD6 ALCAM PPP4R4 NSMAF

1.01e-041489771228611215
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF155 STOX1 ZNF230

1.13e-044277334673265
Pubmed

Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study.

IL12RB2 WNT5A

1.34e-04877220525402
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 THBS2

1.34e-04877224460873
Pubmed

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

THBS1 THBS2

1.72e-0497721371115
Pubmed

FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade.

PTPN13 PIK3CA

2.63e-041177223604317
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPN13 PTPRN

2.63e-04117727832766
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

ZNF410 SEMG2 THBS1 ZNF736 ADNP PPP4R4

3.95e-0443177633660365
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF410 JARID2 PATZ1 TUT7 SCAPER EPAS1 ZFP37 ZNF367

4.20e-0480877820412781
Pubmed

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

THBS1 THBS2

4.33e-041477228729362
Pubmed

The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.

LORICRIN WNT5A

4.33e-041477217360773
Pubmed

Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.

DRD1 LORICRIN

4.33e-041477211409899
Pubmed

An investigation into the human serum "interactome".

JARID2 SACS SCN5A KCNMA1

4.71e-0416277415174051
Pubmed

Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation.

THBS2 WNT5A

4.99e-041577220458143
Pubmed

Tsukushi controls the hair cycle by regulating TGF-β1 signaling.

LORICRIN WNT5A

4.99e-041577222995554
Pubmed

DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.

TET2 LORICRIN

4.99e-041577236630508
Pubmed

Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration.

THBS1 EPAS1

5.69e-041677231669249
Pubmed

A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.

DRD1 WNT5A

5.69e-041677229659809
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 DLG5 AARS1 PTPN13 MYO9A PATZ1 NADK PPP4R4

6.37e-0486177836931259
Pubmed

Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.

ELOA2 EPAS1

6.44e-041777217170753
Pubmed

SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling.

WNT5A ALCAM

6.44e-041777221471156
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF138 ZNF155

6.44e-04177727557990
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

DLG5 THBS1 PATZ1 USP1

7.29e-0418277431067453
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

BCL9L AARS1 THBS1 SACS GOLGA3

8.66e-0433277537433992
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF155 ZNF230

8.96e-042077212743021
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

THBS1 THBS2 WNT5A

9.36e-048677328327460
Pubmed

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.

PTPN13 GOLGA3

9.89e-042177224923560
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 PTPN13 MYO9A GOLGA3

1.22e-0320977436779422
Pubmed

Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.

THBS1 WNT5A

1.29e-032477224161848
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

SMC3 MYO9A LORICRIN

1.36e-039877334943047
Pubmed

Genome-wide association analyses identify variants in developmental genes associated with hypospadias.

EEFSEC KCNMA1

1.40e-032577225108383
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SACS SEL1L3 ADNP

1.49e-031017739872452
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

TET2 SMC3

1.64e-032777223395962
Pubmed

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

SACS ZNF619 USP1

1.66e-0310577323284306
Pubmed

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.

WNT5A EPAS1

1.76e-032877218367557
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

XIRP1 PATZ1 BANP SCAPER

1.81e-0323377437704626
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF727 ZNF736

1.89e-032977214563677
Pubmed

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

THBS1 THBS2

2.02e-033077222171010
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TET2 AARS1 DMXL2 THBS1 PTPN13 SACS CHD6 ZNF619 GOLGA3

2.11e-03128577935914814
Cytoband7q11.21

ZNF138 ZNF117 ZNF727 ZNF736

1.22e-05837747q11.21
CytobandEnsembl 112 genes in cytogenetic band chr9q22

ERCC6L2 ZNF510 ZNF367 NOL8

3.69e-04200774chr9q22
Cytoband9q22.32

ERCC6L2 ZNF367

9.48e-04277729q22.32
CytobandEnsembl 112 genes in cytogenetic band chr7q11

ZNF138 ZNF117 ZNF727 ZNF736

1.15e-03271774chr7q11
CytobandEnsembl 112 genes in cytogenetic band chr3p22

XIRP1 SCN5A ZNF619

3.73e-03184773chr3p22
CytobandEnsembl 112 genes in cytogenetic band chr10q22

DLG5 KCNMA1 STOX1

5.24e-03208773chr10q22
CytobandEnsembl 112 genes in cytogenetic band chr1p31

IL12RB2 SLC44A5 USP1

6.43e-03224773chr1p31
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF410 ZNF138 ZNF117 ZNF613 ZNF155 PATZ1 SCAPER ZNF727 ZNF736 ZNF510 ZNF619 ZNF30 ZNF230 ZNF418 ZFP37 ZNF367

4.52e-11718501628
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

ZNF138 PTPN13 ASRGL1 ZNF117 SACS SMC3 MYO9A PIK3CA TUT7 ARHGAP44 USP1

2.91e-066567611M18979
CoexpressionZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN

THBS1 SMC3 RTN4IP1 USP1 ZNF367

1.45e-05106765M9160
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

THBS1 THBS2 PIK3CA WNT5A KCNMA1 ZNF385B

7.67e-07185766427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC44A5 ARHGAP44 SEL1L3 ZNF385B ALCAM PPP4R4

7.92e-071867662ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

AARS1 PTPN13 ABCA13 ARHGAP44 ZNF385B PPP4R4

8.43e-07188766ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 SLC44A5 MYO9A ABCA13 WNT5A SEL1L3

9.82e-07193766ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 WNT5A SEL1L3 KCNMA1 ZNF385B

1.04e-061957663f64e2313ec79a6d5f4013a52722d071172f6c5d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 WNT5A SEL1L3 KCNMA1 ZNF385B

1.04e-061957667a5108335353ac160b684650c5da97d6f7f4dbcf
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF138 WNT5A SEL1L3 ZNF736 ZNF367

6.90e-06155765d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PATZ1 WNT5A DEPDC5 RTN4IP1 ZNF736

1.08e-05170765adf73bdc049d508f8873c22539db2ca92052a97b
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THBS1 WNT5A KCNMA1 ZNF385B ZNF30

1.24e-05175765a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

SLC44A5 WNT5A TUT7 SEL1L3 CHD6

1.62e-051857656814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPTLC3 SLC44A5 MYO9A ABCA13 SEL1L3

1.67e-051867653dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC44A5 ARHGAP44 SEL1L3 ZNF385B ALCAM

1.75e-051887650d86044bc340e3efb90d0022dd299873639d831c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_P2ry12|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NUGGC THBS2 DRD1 WDR49

1.80e-05917643f56358ff0dacdf6b8fc22cea64082231bceb851
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 SLC44A5 MYO9A ABCA13 SEL1L3

1.80e-05189765bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPN13 OVCH2 ARHGAP44 ZNF385B ALCAM

1.85e-051907658aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

TET2 JARID2 DMXL2 THBS1 KCNMA1

1.85e-05190765d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 WNT5A KCNMA1 ZNF385B

1.85e-05190765c7bd087f36321cec61b98657433b4d19d135791f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 WNT5A KCNMA1 ZNF385B

1.85e-05190765834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

PTPN13 OVCH2 ARHGAP44 ZNF385B ALCAM

1.89e-05191765d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPN13 ASRGL1 ARHGAP44 ZNF385B PPP4R4

1.94e-05192765cc9911e182a289779a2612bc213daae5607689e7
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPN13 MYO9A ARHGAP44 ZNF385B ALCAM

2.04e-0519476553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

TET2 JARID2 DMXL2 THBS1 KCNMA1

2.04e-051947657d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellControl-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

TET2 JARID2 DMXL2 THBS1 KCNMA1

2.04e-05194765c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS1 THBS2 WNT5A KCNMA1 ZNF385B

2.04e-051947657bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 SLC44A5 MYO9A ABCA13 SEL1L3

2.04e-051947658ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS1 THBS2 WNT5A KCNMA1 ZNF385B

2.04e-0519476519e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPN13 MYO9A ARHGAP44 ZNF385B ALCAM

2.09e-051957659406866f99555198a9be311fbd65751b70f35446
ToppCellControl-Myeloid-Macrophage|Control / Disease state, Lineage and Cell class

JARID2 DMXL2 THBS1 KCNMA1 ALCAM

2.14e-05196765e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 SLC44A5 WNT5A SEL1L3 ALCAM

2.25e-05198765af399569c718f5fd971d73a7926768c9311002a3
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN13 ASRGL1 ABCA13 ALCAM EPAS1

2.25e-05198765484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPN13 ASRGL1 ABCA13 ALCAM EPAS1

2.25e-051987657d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 MYO9A ARHGAP44 SCAPER ZNF385B

2.25e-051987651996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 SLC44A5 WNT5A SEL1L3 ALCAM

2.25e-051987651408e02e053ad3406229bfe8189da03be6366e81
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN13 ASRGL1 ABCA13 ALCAM EPAS1

2.25e-051987654a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WNT5A CCDC62 KCNMA1 ZNF619 STOX1

2.25e-05198765cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTLC3 PTPN13 ARHGAP44 ZNF385B ALCAM

2.30e-05199765725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 MYO9A ARHGAP44 ZNF385B ALCAM

2.30e-051997658587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN13 MYO9A ARHGAP44 ZNF385B ALCAM

2.30e-051997655cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellCOPD-Myeloid-Macrophage|COPD / Disease state, Lineage and Cell class

TET2 JARID2 DMXL2 KCNMA1 ALCAM

2.30e-051997654b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TET2 JARID2 DMXL2 THBS1 NSMAF

2.30e-05199765379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellNS-moderate-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN13 ASRGL1 ABCA13 ALCAM EPAS1

2.36e-0520076585940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DLG5 PTPN13 ABCA13 ALCAM EPAS1

2.36e-0520076597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DLG5 PTPN13 ABCA13 ALCAM EPAS1

2.36e-05200765ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_P2ry12|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NUGGC DLG5 DRD1 EPAS1

7.49e-0513176480630812f8894b9358d36dc2dd03fea7ee870502
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NUGGC DLG5 THBS2 DRD1

9.68e-0514076417005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NUGGC SLC44A5 MYO9A ABCA13

1.05e-041437647a7a9829ba63468c9745904d9e993590051207ab
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS2 SLC44A5 WNT5A ALCAM

1.23e-041497645293c50b3fb41b1edaf9a97354899bd13770078c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

1.30e-0415176416fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 ZNF385B

1.36e-04153764d6526d17826470534b766df144c74e73eb83fdad
ToppCellMS-CD8-memory_CD4|MS / Condition, Cell_class and T cell subcluster

ZNF410 ZNF385D IMPA1 EPAS1

1.40e-04154764aec893cf3e1cf90e18a9117183fc7a1f397425a9
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

TUT7 BANP ZNF367

1.55e-0461763d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TET2 JARID2 THBS1 TUT7

1.62e-041607646ed37d1fd0304932319d6b942502404115ff36a7
ToppCell356C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF155 SEL1L3 STOX1 WDR49

1.78e-04164764fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SMC3 ERCC6L2 DEPDC5 NOL8

1.86e-04166764f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.04e-041707645d5f208682be21ed58320f5fc083a7898f8712da
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF138 SACS SEL1L3 ERCC6L2

2.04e-0417076432917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HGD ALCAM USP1 ZNF367

2.04e-041707644ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TET2 JARID2 THBS1 ALCAM

2.04e-04170764cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 THBS1 ABCA13 NADK

2.09e-04171764ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 THBS1 ABCA13 NADK

2.09e-0417176497ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF385D DLG5 SEL1L3 ALCAM

2.18e-04173764b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular|TCGA-Thryoid / Sample_Type by Project: Shred V9

HGD ASRGL1 ESAM RTN4IP1

2.28e-0417576449211b260bbe3c88354fbd1953dc06f92d3eab09
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

PTPRN SEL1L3 KCNMA1 PPP4R4

2.33e-04176764d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRN CCDC62 ERCC6L2 USP1

2.33e-041767641510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

HGD PTPN13 WNT5A ZNF385B

2.33e-041767643fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB2 PTS RTN4IP1 NSMAF

2.33e-041767643c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.33e-04176764327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.38e-04177764da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|normal_Lymph_Node / Location, Cell class and cell subclass

NUGGC SEL1L3 KCNMA1 ZNF385B

2.43e-04178764d75057e7463558a0d3cebde3c30befbf4704dd9a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.43e-04178764c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

OVCH2 WNT5A ARHGAP44 ZNF385B

2.49e-04179764cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AARS1 SEL1L3 KCNMA1 ZFP37

2.54e-041807648e96f8646c002768b272359af485dc0ab57e0ccd
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 THBS1 XIRP1 KCNMA1

2.54e-04180764d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 THBS1 XIRP1 KCNMA1

2.54e-04180764573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.59e-041817646a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.59e-041817649d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D NUGGC THBS2 WNT5A

2.59e-04181764b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.59e-04181764071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.59e-041817646956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D ASRGL1 ESAM EPAS1

2.65e-041827643cbeaf7904a76c32137a00abb20e302d3d3c8bb8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.65e-04182764eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.70e-04183764738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

OVCH2 ARHGAP44 ZNF385B ALCAM

2.70e-041837647b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.70e-04183764cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.70e-0418376492fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HGD THBS1 PTPRN ESAM

2.76e-04184764a5d904dd030d9c21be0f8b9ec432025f90fb5b8e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 DMXL2 THBS1 TUT7

2.76e-04184764d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellcontrol-Others|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HGD THBS1 PTPRN ESAM

2.76e-04184764a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

THBS2 IMPA1 SEL1L3 NSMAF

2.76e-041847649c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.76e-04184764da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGD THBS1 PTPRN ESAM

2.76e-041847647617a00b2ebd6c5c9386c39a7e8220fdbf8669ff
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HGD THBS1 PTPRN ESAM

2.76e-04184764213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 PTPN13 ABCA13 EPAS1

2.82e-04185764e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 MYO9A ABCA13 SEL1L3

2.88e-041867645c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPN13 ABCA13 ARHGAP44 SEL1L3

2.88e-04186764acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTLC3 SLC44A5 MYO9A ABCA13

2.88e-04186764f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP44 SEL1L3 ZNF385B ALCAM

2.88e-04186764c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTLC3 SLC44A5 MYO9A ABCA13

2.94e-04187764c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP44 SEL1L3 ZNF385B ALCAM

2.94e-04187764a5318c888b334e8695f38971a7d100b93cdaf04b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPN13 MYO9A ARHGAP44 ZNF385B

2.94e-0418776458d48128547ee3513d0bf7f78e61b76b1c472ca9
DiseaseColorectal Carcinoma

TET2 ZNF385D ELOA2 ZNF155 SACS ABCA13 PIK3CA CCDC62 WDR49

7.18e-05702759C0009402
Diseasecervical cancer

ZNF385D JARID2 STOX1

1.46e-0440753MONDO_0002974
DiseasePapillary Renal Cell Carcinoma

TET2 PIK3CA KCNMA1 EPAS1

3.24e-04128754C1306837
DiseaseRenal Cell Carcinoma

TET2 PIK3CA KCNMA1 EPAS1

3.24e-04128754C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

TET2 PIK3CA KCNMA1 EPAS1

3.24e-04128754C1266043
DiseaseChromophobe Renal Cell Carcinoma

TET2 PIK3CA KCNMA1 EPAS1

3.24e-04128754C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

TET2 PIK3CA KCNMA1 EPAS1

3.24e-04128754C1266044
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

TET2 PIK3CA KCNMA1 EPAS1

5.60e-04148754C0279702
DiseaseP wave duration

SCN5A EPAS1

6.55e-0415752EFO_0005094
DiseaseDiabetic Angiopathies

THBS1 THBS2

7.48e-0416752C0011875
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

7.48e-0416752C0025945
DiseaseFetal Alcohol Syndrome

PIK3CA ADNP

8.46e-0417752C0015923
Diseasehepatocellular carcinoma (is_implicated_in)

TET2 PTPN13 SMC3 PIK3CA

1.19e-03181754DOID:684 (is_implicated_in)
Diseasehyperglycemia (biomarker_via_orthology)

DRD1 EPAS1

1.30e-0321752DOID:4195 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NKGNTGLQNKTFHCE

ZNF385D

256

Q9H6B1
AVSNLSGQGKHGKKQ

BANP

266

Q8N9N5
HCRGVGKTQNGQDKT

ADNP

686

Q9H2P0
KSHQNLCTKGQVVSG

EPAS1

291

Q99814
KCHGTGVQNEGKQPS

CCDC62

436

Q6P9F0
GAQKTDCQKNLGTVG

ASRGL1

156

Q7L266
CLQGEGQGHLSQKKT

GSDMD

191

P57764
NGSFKCLGSPQHIKN

ABCA13

4931

Q86UQ4
KQQLLISGGRKGHVC

DMXL2

2911

Q8TDJ6
VHAKNCQTTTGNGKP

DRD1

236

P21728
GCQTHSGEKILENGL

CAPN14

236

A8MX76
QKCLGEQQAAVHGGK

DEPDC5

1051

O75140
CQGQPQGKAVVSHSK

ELOA2

211

Q8IYF1
CATAQGEGNIKKNRH

PTPRN

726

Q16849
CGGKTKEAQKINNGS

KCNMA1

121

Q12791
QGGCSSILGNSKHKA

IL12RB2

506

Q99665
KKTAVHNGLGENGSQ

NADK

251

O95544
KKSQLELGVHLCGGN

DLG5

1506

Q8TDM6
SGKGVPICHQTQQKQ

LORICRIN

291

P23490
NGSLGEVTPCQHAKK

NOL8

621

Q76FK4
HEKGKLTGLGQSNAA

GOLGA3

1116

Q08378
QCKGGLKGALQFNSH

PIK3CA

861

P42336
GCLITLDQHNGKKSQ

ERCC8

221

Q13216
GNKEGQKCSHQDPIE

PATZ1

546

Q9HBE1
QAQEKHGESQEGKPC

CEFIP

1196

Q711Q0
AGGVAQANIKNGKHL

CHD6

1766

Q8TD26
ENKLTNHGKTGNGGA

BCL9L

41

Q86UU0
CSVNVQDKQGKSRGH

ESAM

126

Q96AP7
GHDGSKRGQQQITGK

ENO4

341

A6NNW6
DCIKIGKHGENGANR

NSMAF

81

Q92636
GHFCGQKGTPNENKT

SLC44A5

76

Q8NCS7
GCEKNQDSLGTSKHQ

ERCC6L2

846

Q5T890
CQTGGKSKRTIQGTH

SCAPER

46

Q9BY12
NCHLFVNLQSKGLKG

SACS

71

Q9NZJ4
KEGDNITLKCLGNGN

ALCAM

261

Q13740
GIKHGFQTDNSKICQ

PTPN13

841

Q12923
LHTLCGAGDIKSNNG

HGD

116

Q93099
SLVNQICGKVSGKNG

JARID2

1191

Q92833
AINKVGGLNDKNCTG

RTN4IP1

191

Q8WWV3
GNQGFHQTLKAVCLK

NUGGC

541

Q68CJ6
KAASKGLHQAVNGLG

SEL1L3

756

Q68CR1
KHNVIVGRNGSGKSN

SMC3

26

Q9UQE7
KKLCTLGLQQENGHN

PPP4R4

341

Q6NUP7
GKGAFCNGQKLQVSQ

IMPA1

136

P29218
QVSLKQRQKHICGGS

OVCH2

66

Q7RTZ1
ALHGKKNSTVDCNGV

SCN5A

586

Q14524
RHLNCGEKGIQKGVS

SEMG2

356

Q02383
GGAVCNGKLHNHKKQ

SPTLC3

6

Q9NUV7
THKKLTACLQGQQGA

ARHGAP44

46

Q17R89
KECGKNFSNGHQLTI

ZNF30

151

P17039
GNCKGQKSSYNGIHQ

ZNF727

121

A8MUV8
KKAGQATEGHCPRQQ

EEFSEC

396

P57772
GQGVEHATANKQVCK

THBS1

631

P07996
KGHQGGFNGLNQCLK

ZNF138

61

P52744
NTQKCIRAGGKHNDL

AARS1

71

P49588
IQDCGGHKVKGLTQD

SPEM3

921

A0A1B0GUW6
TGGSQGNHLGKQKVI

STOX1

761

Q6ZVD7
CGKQFTTAGNLKNHR

ZNF410

286

Q86VK4
QKIKQFTGCHGNAEI

WDR49

181

Q8IV35
QLAGLSQGQKKLCHL

WNT5A

71

P41221
NGSKGSGLQNKTFHC

ZNF385B

336

Q569K4
CGKSFSRKGNLIQHQ

ZNF418

431

Q8TF45
DCGKGFIQKGNLIVH

ZNF613

376

Q6PF04
SIIHTGQKPSQNGKC

ZNF230

131

Q9UIE0
IHTGQKPSQGGKCKQ

ZNF155

141

Q12901
QHKGDYSGLNQCLKT

ZNF117

61

Q03924
RTGTGKKHLHLNQCG

ZNF510

301

Q9Y2H8
CGKTFGQKSNLRIHQ

ZNF510

521

Q9Y2H8
LSKKGCQQGQGAEIN

THBS2

221

P35442
DCGKAFVQSGQLKTH

ZNF367

201

Q7RTV3
KQSGLLCKVSAGNEN

TUT7

401

Q5VYS8
CVQGGLHKLSDANGQ

TET2

1811

Q6N021
QLHDTGNKTKIGDCT

ZNF619

131

Q8N2I2
NQCGKVLSHKQGLID

ZFP37

296

Q9Y6Q3
QCGKGFKQIEGLTQH

ZFP37

521

Q9Y6Q3
NLKLFGKCNNPNGHG

PTS

36

Q03393
GQALLHQKGVQDKTG

XIRP1

1706

Q702N8
CSLGKITTNQGVKGQ

USP1

356

O94782
GNCKGQKSSYNGLHQ

ZNF736

121

B4DX44
KNQCIVISGESGSGK

MYO9A

231

B2RTY4